Incidental Mutation 'R4842:Myh7b'
| ID |
371889 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh7b
|
| Ensembl Gene |
ENSMUSG00000074652 |
| Gene Name |
myosin, heavy chain 7B, cardiac muscle, beta |
| Synonyms |
Myh14 |
| MMRRC Submission |
042455-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4842 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
155453132-155476227 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 155475909 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Leucine to Methionine
at position 1935
(L1935M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000090672
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041059]
[ENSMUST00000092995]
[ENSMUST00000103140]
|
| AlphaFold |
A2AQP0 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041059
|
| SMART Domains |
Protein: ENSMUSP00000037574
Gene: ENSMUSG00000038324
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
35 |
N/A |
INTRINSIC |
|
low complexity region
|
38 |
53 |
N/A |
INTRINSIC |
|
Pfam:DUF3689
|
407 |
714 |
5.2e-135 |
PFAM |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000092995
AA Change: L1935M
PolyPhen 2
Score 0.447 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000090672
Gene: ENSMUSG00000074652
AA Change: L1935M
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
32 |
72 |
4.7e-14 |
PFAM |
|
MYSc
|
78 |
786 |
N/A |
SMART |
|
IQ
|
787 |
809 |
2.6e0 |
SMART |
|
Pfam:Myosin_tail_1
|
850 |
1931 |
5.5e-149 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000103140
|
| SMART Domains |
Protein: ENSMUSP00000099429
Gene: ENSMUSG00000038324
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
35 |
N/A |
INTRINSIC |
|
low complexity region
|
38 |
53 |
N/A |
INTRINSIC |
|
Pfam:DUF3689
|
399 |
710 |
1.1e-138 |
PFAM |
|
low complexity region
|
716 |
727 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124415
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143115
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146484
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000152548
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000154656
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000153246
|
| Meta Mutation Damage Score |
0.0690 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.6%
|
| Validation Efficiency |
95% (107/113) |
| MGI Phenotype |
FUNCTION: This gene encodes a myosin heavy chain. The encoded protein forms a hexamer comprised of two heavy chains, two alkali light chains, and two regulatory light chain components. This complex functions in muscle contraction. [provided by RefSeq, Jun 2013]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1600012H06Rik |
A |
T |
17: 15,164,001 (GRCm39) |
I43L |
possibly damaging |
Het |
| 4930449A18Rik |
T |
A |
3: 59,749,153 (GRCm39) |
|
noncoding transcript |
Het |
| Abcc8 |
T |
C |
7: 45,800,252 (GRCm39) |
K510R |
probably damaging |
Het |
| Adamtsl3 |
C |
T |
7: 82,178,069 (GRCm39) |
R511C |
probably damaging |
Het |
| Arhgap11a |
T |
C |
2: 113,670,107 (GRCm39) |
S339G |
probably damaging |
Het |
| C2cd3 |
A |
G |
7: 100,065,397 (GRCm39) |
T728A |
probably benign |
Het |
| Cand1 |
C |
A |
10: 119,049,451 (GRCm39) |
|
probably null |
Het |
| Catspere1 |
A |
T |
1: 177,699,624 (GRCm39) |
|
noncoding transcript |
Het |
| Ccdc121rt2 |
A |
T |
5: 112,598,106 (GRCm39) |
K218* |
probably null |
Het |
| Cd209c |
G |
T |
8: 3,995,905 (GRCm39) |
R2S |
probably benign |
Het |
| Cdc16 |
A |
G |
8: 13,831,644 (GRCm39) |
|
probably benign |
Het |
| Ces1g |
C |
T |
8: 94,060,323 (GRCm39) |
E99K |
probably benign |
Het |
| Chrna7 |
A |
C |
7: 62,862,196 (GRCm39) |
L10R |
probably benign |
Het |
| Clnk |
C |
T |
5: 38,870,412 (GRCm39) |
|
probably null |
Het |
| Cntrob |
C |
G |
11: 69,206,220 (GRCm39) |
L315F |
possibly damaging |
Het |
| Ctdp1 |
A |
G |
18: 80,451,941 (GRCm39) |
S145P |
unknown |
Het |
| Dennd2a |
T |
C |
6: 39,474,044 (GRCm39) |
D430G |
probably damaging |
Het |
| Dnajc16 |
A |
G |
4: 141,501,936 (GRCm39) |
F298S |
probably damaging |
Het |
| Dock5 |
T |
C |
14: 68,055,012 (GRCm39) |
D618G |
probably damaging |
Het |
| Drc3 |
G |
A |
11: 60,261,361 (GRCm39) |
A171T |
probably benign |
Het |
| Ecel1 |
A |
T |
1: 87,081,023 (GRCm39) |
N322K |
probably damaging |
Het |
| Eftud2 |
A |
G |
11: 102,745,640 (GRCm39) |
F362L |
probably damaging |
Het |
| Egfr |
C |
T |
11: 16,861,607 (GRCm39) |
H1129Y |
probably benign |
Het |
| Eif2b1 |
A |
G |
5: 124,714,971 (GRCm39) |
S102P |
probably damaging |
Het |
| Erich3 |
T |
A |
3: 154,410,480 (GRCm39) |
F112I |
possibly damaging |
Het |
| Fam107b |
T |
C |
2: 3,779,580 (GRCm39) |
L261S |
probably damaging |
Het |
| Fat3 |
A |
C |
9: 15,908,883 (GRCm39) |
V2373G |
probably damaging |
Het |
| Fcgbpl1 |
T |
A |
7: 27,850,147 (GRCm39) |
C1198S |
probably damaging |
Het |
| Gadd45a |
A |
T |
6: 67,013,873 (GRCm39) |
L58Q |
probably damaging |
Het |
| Gask1b |
G |
A |
3: 79,843,912 (GRCm39) |
R377H |
probably damaging |
Het |
| Gipr |
C |
T |
7: 18,896,601 (GRCm39) |
R165H |
probably damaging |
Het |
| Gje1 |
C |
T |
10: 14,593,082 (GRCm39) |
G45R |
probably null |
Het |
| Gldc |
T |
A |
19: 30,111,132 (GRCm39) |
N548I |
possibly damaging |
Het |
| Gm13035 |
A |
G |
4: 146,009,993 (GRCm39) |
|
noncoding transcript |
Het |
| Gm27013 |
T |
A |
6: 130,497,700 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5436 |
A |
T |
12: 84,305,584 (GRCm39) |
|
noncoding transcript |
Het |
| Grik3 |
C |
A |
4: 125,584,969 (GRCm39) |
N612K |
probably damaging |
Het |
| H2bc13 |
C |
T |
13: 21,900,234 (GRCm39) |
|
probably benign |
Het |
| Hfm1 |
C |
A |
5: 107,040,617 (GRCm39) |
W716L |
probably damaging |
Het |
| Il5ra |
T |
C |
6: 106,715,336 (GRCm39) |
Y166C |
probably damaging |
Het |
| Iqcb1 |
A |
G |
16: 36,655,952 (GRCm39) |
E113G |
probably benign |
Het |
| Kcnk10 |
A |
T |
12: 98,401,175 (GRCm39) |
M486K |
probably benign |
Het |
| Kcnv2 |
A |
G |
19: 27,301,190 (GRCm39) |
D347G |
probably damaging |
Het |
| Kif21b |
C |
A |
1: 136,072,958 (GRCm39) |
H119N |
probably damaging |
Het |
| Lamb1 |
C |
T |
12: 31,337,432 (GRCm39) |
H388Y |
probably damaging |
Het |
| Leng9 |
T |
C |
7: 4,152,385 (GRCm39) |
D97G |
probably damaging |
Het |
| Lmbr1 |
G |
A |
5: 29,492,424 (GRCm39) |
T55I |
probably damaging |
Het |
| Lrp1 |
G |
T |
10: 127,419,805 (GRCm39) |
R935S |
probably damaging |
Het |
| Lrp2 |
A |
T |
2: 69,299,755 (GRCm39) |
V3099E |
probably benign |
Het |
| Lrrcc1 |
C |
A |
3: 14,627,571 (GRCm39) |
D503E |
probably benign |
Het |
| Map1a |
T |
A |
2: 121,132,567 (GRCm39) |
S890T |
probably damaging |
Het |
| Msh2 |
C |
A |
17: 88,030,841 (GRCm39) |
A906E |
probably benign |
Het |
| Mybph |
A |
T |
1: 134,126,233 (GRCm39) |
E349V |
probably damaging |
Het |
| Myh9 |
T |
C |
15: 77,653,453 (GRCm39) |
E1348G |
probably damaging |
Het |
| Myzap |
A |
G |
9: 71,456,037 (GRCm39) |
S328P |
probably damaging |
Het |
| Nbeal1 |
T |
C |
1: 60,292,534 (GRCm39) |
L1062P |
probably damaging |
Het |
| Nepro |
G |
A |
16: 44,555,160 (GRCm39) |
S412N |
probably null |
Het |
| Nr1h3 |
A |
G |
2: 91,020,563 (GRCm39) |
F257L |
probably benign |
Het |
| Nudt5 |
T |
C |
2: 5,869,239 (GRCm39) |
V155A |
probably benign |
Het |
| Ofcc1 |
G |
A |
13: 40,168,864 (GRCm39) |
T841I |
probably damaging |
Het |
| Or13a25 |
A |
T |
7: 140,247,502 (GRCm39) |
I94F |
probably damaging |
Het |
| Or52d3 |
A |
T |
7: 104,229,422 (GRCm39) |
I190L |
probably benign |
Het |
| Or6ae1 |
A |
G |
7: 139,742,602 (GRCm39) |
L87P |
possibly damaging |
Het |
| Pde1a |
T |
A |
2: 79,959,181 (GRCm39) |
|
probably benign |
Het |
| Pde4dip |
T |
A |
3: 97,700,844 (GRCm39) |
H220L |
probably damaging |
Het |
| Pde9a |
T |
A |
17: 31,662,135 (GRCm39) |
|
probably null |
Het |
| Pnkp |
C |
A |
7: 44,511,070 (GRCm39) |
|
probably null |
Het |
| Pnpla7 |
A |
G |
2: 24,870,064 (GRCm39) |
T15A |
probably benign |
Het |
| Polq |
G |
T |
16: 36,869,145 (GRCm39) |
|
probably null |
Het |
| Ppfia2 |
C |
T |
10: 106,690,818 (GRCm39) |
T553I |
probably benign |
Het |
| Ptk6 |
T |
G |
2: 180,838,784 (GRCm39) |
N323T |
possibly damaging |
Het |
| Rhox3c |
G |
A |
X: 36,652,077 (GRCm39) |
A60T |
probably damaging |
Het |
| Rnf4 |
T |
A |
5: 34,506,053 (GRCm39) |
V61E |
probably damaging |
Het |
| Rnf5 |
A |
G |
17: 34,820,977 (GRCm39) |
|
probably benign |
Het |
| Sardh |
A |
G |
2: 27,081,967 (GRCm39) |
V853A |
probably benign |
Het |
| Scfd1 |
T |
C |
12: 51,436,109 (GRCm39) |
V86A |
probably damaging |
Het |
| Scube3 |
G |
A |
17: 28,383,097 (GRCm39) |
C425Y |
probably damaging |
Het |
| Sema5a |
C |
T |
15: 32,609,563 (GRCm39) |
H490Y |
probably benign |
Het |
| Sfta2 |
T |
C |
17: 35,960,773 (GRCm39) |
|
probably benign |
Het |
| Sh3d19 |
T |
C |
3: 86,031,049 (GRCm39) |
Y738H |
probably damaging |
Het |
| Shc2 |
T |
C |
10: 79,458,295 (GRCm39) |
R463G |
probably damaging |
Het |
| Socs7 |
T |
A |
11: 97,267,829 (GRCm39) |
I320N |
possibly damaging |
Het |
| Speer2 |
A |
T |
16: 69,654,988 (GRCm39) |
M159K |
probably benign |
Het |
| Sppl2c |
A |
C |
11: 104,078,478 (GRCm39) |
H426P |
probably benign |
Het |
| Stag3 |
T |
G |
5: 138,307,627 (GRCm39) |
|
probably null |
Het |
| Stxbp5 |
C |
A |
10: 9,638,635 (GRCm39) |
V1055L |
probably benign |
Het |
| Synpo |
A |
T |
18: 60,736,684 (GRCm39) |
S421T |
probably damaging |
Het |
| Taf6l |
A |
G |
19: 8,759,770 (GRCm39) |
V135A |
possibly damaging |
Het |
| Tas2r116 |
G |
A |
6: 132,832,660 (GRCm39) |
S87N |
probably benign |
Het |
| Tomm6 |
T |
C |
17: 47,998,994 (GRCm39) |
|
probably benign |
Het |
| Trabd |
T |
C |
15: 88,966,915 (GRCm39) |
M113T |
probably benign |
Het |
| Trim58 |
G |
A |
11: 58,542,150 (GRCm39) |
G370E |
probably damaging |
Het |
| Ttc41 |
C |
T |
10: 86,566,989 (GRCm39) |
R552C |
probably benign |
Het |
| Vit |
T |
C |
17: 78,909,308 (GRCm39) |
S252P |
probably benign |
Het |
| Vma21-ps |
T |
A |
4: 52,496,943 (GRCm39) |
D101V |
probably damaging |
Het |
| Vmn1r173 |
A |
T |
7: 23,402,361 (GRCm39) |
I199F |
probably damaging |
Het |
| Vmn2r114 |
T |
A |
17: 23,529,336 (GRCm39) |
R255S |
probably benign |
Het |
| Vmn2r17 |
A |
G |
5: 109,582,246 (GRCm39) |
N545S |
probably damaging |
Het |
| Zfp865 |
A |
G |
7: 5,034,640 (GRCm39) |
Y875C |
probably damaging |
Het |
|
| Other mutations in Myh7b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00931:Myh7b
|
APN |
2 |
155,472,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01604:Myh7b
|
APN |
2 |
155,474,327 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02179:Myh7b
|
APN |
2 |
155,456,411 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02729:Myh7b
|
APN |
2 |
155,467,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02804:Myh7b
|
APN |
2 |
155,467,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02851:Myh7b
|
APN |
2 |
155,470,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02956:Myh7b
|
APN |
2 |
155,467,874 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02956:Myh7b
|
APN |
2 |
155,474,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02992:Myh7b
|
APN |
2 |
155,463,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03060:Myh7b
|
APN |
2 |
155,474,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03061:Myh7b
|
APN |
2 |
155,462,031 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03226:Myh7b
|
APN |
2 |
155,462,403 (GRCm39) |
nonsense |
probably null |
|
|
IGL03246:Myh7b
|
APN |
2 |
155,459,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03382:Myh7b
|
APN |
2 |
155,465,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
euclidian
|
UTSW |
2 |
155,475,319 (GRCm39) |
missense |
probably benign |
0.32 |
|
imaginary
|
UTSW |
2 |
155,474,175 (GRCm39) |
missense |
probably benign |
0.36 |
|
Irrational
|
UTSW |
2 |
155,472,592 (GRCm39) |
unclassified |
probably benign |
|
|
Muscoli
|
UTSW |
2 |
155,462,038 (GRCm39) |
nonsense |
probably null |
|
|
R0015:Myh7b
|
UTSW |
2 |
155,464,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0015:Myh7b
|
UTSW |
2 |
155,464,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Myh7b
|
UTSW |
2 |
155,453,594 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0309:Myh7b
|
UTSW |
2 |
155,472,592 (GRCm39) |
unclassified |
probably benign |
|
|
R0567:Myh7b
|
UTSW |
2 |
155,468,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0619:Myh7b
|
UTSW |
2 |
155,453,642 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0927:Myh7b
|
UTSW |
2 |
155,462,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R0973:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R0974:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R1137:Myh7b
|
UTSW |
2 |
155,464,634 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1261:Myh7b
|
UTSW |
2 |
155,463,003 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1268:Myh7b
|
UTSW |
2 |
155,455,966 (GRCm39) |
nonsense |
probably null |
|
|
R1537:Myh7b
|
UTSW |
2 |
155,473,707 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1632:Myh7b
|
UTSW |
2 |
155,462,445 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1694:Myh7b
|
UTSW |
2 |
155,455,113 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1697:Myh7b
|
UTSW |
2 |
155,462,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1730:Myh7b
|
UTSW |
2 |
155,467,592 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1762:Myh7b
|
UTSW |
2 |
155,472,778 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1783:Myh7b
|
UTSW |
2 |
155,467,592 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2105:Myh7b
|
UTSW |
2 |
155,471,377 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2140:Myh7b
|
UTSW |
2 |
155,462,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2971:Myh7b
|
UTSW |
2 |
155,474,175 (GRCm39) |
missense |
probably benign |
0.36 |
|
R3838:Myh7b
|
UTSW |
2 |
155,474,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4074:Myh7b
|
UTSW |
2 |
155,460,678 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4191:Myh7b
|
UTSW |
2 |
155,475,319 (GRCm39) |
missense |
probably benign |
0.32 |
|
R4689:Myh7b
|
UTSW |
2 |
155,472,434 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4695:Myh7b
|
UTSW |
2 |
155,456,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4697:Myh7b
|
UTSW |
2 |
155,471,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4771:Myh7b
|
UTSW |
2 |
155,468,314 (GRCm39) |
nonsense |
probably null |
|
|
R4794:Myh7b
|
UTSW |
2 |
155,465,186 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4871:Myh7b
|
UTSW |
2 |
155,455,420 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5022:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5023:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5025:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5050:Myh7b
|
UTSW |
2 |
155,473,670 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5055:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5056:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5161:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5284:Myh7b
|
UTSW |
2 |
155,474,234 (GRCm39) |
missense |
probably benign |
|
|
R5422:Myh7b
|
UTSW |
2 |
155,472,954 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5505:Myh7b
|
UTSW |
2 |
155,474,592 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5946:Myh7b
|
UTSW |
2 |
155,463,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6089:Myh7b
|
UTSW |
2 |
155,464,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6103:Myh7b
|
UTSW |
2 |
155,460,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Myh7b
|
UTSW |
2 |
155,473,719 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6292:Myh7b
|
UTSW |
2 |
155,474,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6350:Myh7b
|
UTSW |
2 |
155,470,680 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6484:Myh7b
|
UTSW |
2 |
155,470,563 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6760:Myh7b
|
UTSW |
2 |
155,462,038 (GRCm39) |
nonsense |
probably null |
|
|
R6896:Myh7b
|
UTSW |
2 |
155,464,488 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6945:Myh7b
|
UTSW |
2 |
155,464,152 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7020:Myh7b
|
UTSW |
2 |
155,473,671 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7052:Myh7b
|
UTSW |
2 |
155,456,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7102:Myh7b
|
UTSW |
2 |
155,464,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Myh7b
|
UTSW |
2 |
155,464,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7303:Myh7b
|
UTSW |
2 |
155,460,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7360:Myh7b
|
UTSW |
2 |
155,474,460 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7652:Myh7b
|
UTSW |
2 |
155,474,156 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7678:Myh7b
|
UTSW |
2 |
155,459,698 (GRCm39) |
splice site |
probably null |
|
|
R7703:Myh7b
|
UTSW |
2 |
155,462,356 (GRCm39) |
missense |
probably null |
1.00 |
|
R7711:Myh7b
|
UTSW |
2 |
155,462,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7923:Myh7b
|
UTSW |
2 |
155,467,886 (GRCm39) |
missense |
probably benign |
|
|
R7967:Myh7b
|
UTSW |
2 |
155,456,119 (GRCm39) |
splice site |
probably null |
|
|
R8045:Myh7b
|
UTSW |
2 |
155,455,101 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8176:Myh7b
|
UTSW |
2 |
155,467,886 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8272:Myh7b
|
UTSW |
2 |
155,474,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8560:Myh7b
|
UTSW |
2 |
155,465,124 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8706:Myh7b
|
UTSW |
2 |
155,453,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8824:Myh7b
|
UTSW |
2 |
155,472,301 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8832:Myh7b
|
UTSW |
2 |
155,475,182 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9079:Myh7b
|
UTSW |
2 |
155,465,174 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9151:Myh7b
|
UTSW |
2 |
155,474,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Myh7b
|
UTSW |
2 |
155,463,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Myh7b
|
UTSW |
2 |
155,470,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9357:Myh7b
|
UTSW |
2 |
155,463,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9388:Myh7b
|
UTSW |
2 |
155,472,983 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9583:Myh7b
|
UTSW |
2 |
155,459,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Myh7b
|
UTSW |
2 |
155,455,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9738:Myh7b
|
UTSW |
2 |
155,455,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0013:Myh7b
|
UTSW |
2 |
155,473,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCCATTTTAGTTACCAACGGG -3'
(R):5'- GTCCATGATGTTCTGTTCCCAG -3'
Sequencing Primer
(F):5'- GAAACAAGGCTCTGCATATGGCTC -3'
(R):5'- AGTGGCTACTGCTGCAGAC -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation