Incidental Mutation 'R4828:Alpk2'
| ID |
372627 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Alpk2
|
| Ensembl Gene |
ENSMUSG00000032845 |
| Gene Name |
alpha-kinase 2 |
| Synonyms |
Hak |
| MMRRC Submission |
042444-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4828 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
65398600-65526959 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 65482184 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Glycine
at position 141
(E141G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000114658
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035548]
[ENSMUST00000141250]
|
| AlphaFold |
Q91ZB0 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000035548
AA Change: E608G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000048752
Gene: ENSMUSG00000032845
AA Change: E608G
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
24 |
94 |
9.34e-4 |
SMART |
|
low complexity region
|
196 |
209 |
N/A |
INTRINSIC |
|
low complexity region
|
722 |
734 |
N/A |
INTRINSIC |
|
low complexity region
|
1025 |
1037 |
N/A |
INTRINSIC |
|
low complexity region
|
1337 |
1353 |
N/A |
INTRINSIC |
|
IG
|
1766 |
1849 |
2.27e-2 |
SMART |
|
Alpha_kinase
|
1879 |
2098 |
3.72e-79 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000141250
AA Change: E141G
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000114658
Gene: ENSMUSG00000032845
AA Change: E141G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
255 |
267 |
N/A |
INTRINSIC |
|
low complexity region
|
558 |
570 |
N/A |
INTRINSIC |
|
low complexity region
|
870 |
886 |
N/A |
INTRINSIC |
|
IG
|
1299 |
1382 |
2.27e-2 |
SMART |
|
Alpha_kinase
|
1412 |
1603 |
2.45e-56 |
SMART |
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.8%
|
| Validation Efficiency |
98% (106/108) |
| Allele List at MGI |
All alleles(1) : Targeted, knock-out(1) |
| Other mutations in this stock |
Total: 96 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca14 |
A |
T |
7: 119,815,470 (GRCm39) |
R239S |
probably damaging |
Het |
| Adat3 |
T |
C |
10: 80,442,881 (GRCm39) |
S240P |
probably benign |
Het |
| Agbl5 |
G |
A |
5: 31,048,059 (GRCm39) |
R111H |
probably damaging |
Het |
| Alg2 |
A |
G |
4: 47,471,563 (GRCm39) |
V415A |
probably benign |
Het |
| Ampd1 |
A |
C |
3: 102,988,413 (GRCm39) |
T115P |
probably damaging |
Het |
| Ankrd12 |
A |
G |
17: 66,291,632 (GRCm39) |
L1267P |
probably damaging |
Het |
| Arfgef3 |
A |
T |
10: 18,528,441 (GRCm39) |
S315R |
probably damaging |
Het |
| Atp10d |
A |
C |
5: 72,396,461 (GRCm39) |
D222A |
probably benign |
Het |
| B9d1 |
A |
G |
11: 61,398,461 (GRCm39) |
E47G |
probably damaging |
Het |
| Bag2 |
T |
C |
1: 33,785,968 (GRCm39) |
D118G |
probably damaging |
Het |
| Bnip3l |
G |
T |
14: 67,246,208 (GRCm39) |
P9Q |
probably damaging |
Het |
| Casp8ap2 |
A |
G |
4: 32,639,807 (GRCm39) |
N287S |
probably benign |
Het |
| Ccdc190 |
A |
G |
1: 169,761,465 (GRCm39) |
D189G |
probably damaging |
Het |
| Ccdc88a |
A |
G |
11: 29,413,210 (GRCm39) |
K583E |
probably damaging |
Het |
| Cd84 |
A |
T |
1: 171,700,315 (GRCm39) |
N144I |
probably damaging |
Het |
| Chrnd |
A |
G |
1: 87,119,293 (GRCm39) |
|
probably benign |
Het |
| Clca3b |
G |
T |
3: 144,550,273 (GRCm39) |
T224K |
probably benign |
Het |
| Crcp |
A |
G |
5: 130,088,603 (GRCm39) |
T119A |
probably damaging |
Het |
| Cul2 |
T |
C |
18: 3,431,013 (GRCm39) |
Y596H |
probably damaging |
Het |
| Dip2c |
T |
A |
13: 9,610,715 (GRCm39) |
W356R |
probably damaging |
Het |
| Dlc1 |
T |
A |
8: 37,317,400 (GRCm39) |
Q425L |
possibly damaging |
Het |
| Dnah7b |
T |
A |
1: 46,167,272 (GRCm39) |
V588D |
possibly damaging |
Het |
| Dock4 |
G |
T |
12: 40,718,436 (GRCm39) |
G245W |
probably damaging |
Het |
| Dpf3 |
A |
G |
12: 83,341,273 (GRCm39) |
I160T |
possibly damaging |
Het |
| Dstyk |
A |
G |
1: 132,361,875 (GRCm39) |
T102A |
probably benign |
Het |
| Eif3d |
A |
T |
15: 77,844,229 (GRCm39) |
L425* |
probably null |
Het |
| Elac2 |
A |
G |
11: 64,886,153 (GRCm39) |
E477G |
probably damaging |
Het |
| Ephb3 |
G |
A |
16: 21,033,745 (GRCm39) |
R23H |
possibly damaging |
Het |
| Exd1 |
C |
T |
2: 119,350,807 (GRCm39) |
A485T |
probably benign |
Het |
| Ext2 |
G |
A |
2: 93,626,112 (GRCm39) |
T316I |
probably benign |
Het |
| Fbf1 |
A |
G |
11: 116,039,777 (GRCm39) |
V694A |
probably benign |
Het |
| Fgg |
G |
A |
3: 82,915,677 (GRCm39) |
|
probably benign |
Het |
| Flnb |
G |
A |
14: 7,919,238 (GRCm38) |
V1664I |
probably benign |
Het |
| Flnc |
G |
A |
6: 29,455,166 (GRCm39) |
D1932N |
probably damaging |
Het |
| Gm1818 |
A |
T |
12: 48,602,409 (GRCm39) |
|
noncoding transcript |
Het |
| Gnai1 |
G |
A |
5: 18,496,470 (GRCm39) |
S151L |
probably damaging |
Het |
| Golph3l |
G |
A |
3: 95,499,059 (GRCm39) |
R67H |
possibly damaging |
Het |
| Grk5 |
T |
A |
19: 60,976,213 (GRCm39) |
C42* |
probably null |
Het |
| Herc1 |
G |
A |
9: 66,404,625 (GRCm39) |
|
probably null |
Het |
| Hey2 |
A |
T |
10: 30,710,179 (GRCm39) |
H191Q |
possibly damaging |
Het |
| Il11 |
A |
G |
7: 4,779,481 (GRCm39) |
V8A |
probably benign |
Het |
| Il23r |
G |
A |
6: 67,408,635 (GRCm39) |
P402L |
probably benign |
Het |
| Irf5 |
A |
G |
6: 29,531,140 (GRCm39) |
N2S |
probably damaging |
Het |
| Lamb1 |
T |
C |
12: 31,348,929 (GRCm39) |
Y606H |
probably benign |
Het |
| Larp4b |
C |
T |
13: 9,220,934 (GRCm39) |
R650C |
probably damaging |
Het |
| Lrpap1 |
T |
C |
5: 35,259,765 (GRCm39) |
E111G |
possibly damaging |
Het |
| Lrrc36 |
T |
A |
8: 106,181,862 (GRCm39) |
S388T |
probably benign |
Het |
| Med27 |
T |
C |
2: 29,267,950 (GRCm39) |
|
probably benign |
Het |
| Mrc1 |
T |
G |
2: 14,275,017 (GRCm39) |
D439E |
probably damaging |
Het |
| Notch4 |
A |
T |
17: 34,789,034 (GRCm39) |
E444D |
probably damaging |
Het |
| Nrm |
G |
A |
17: 36,175,082 (GRCm39) |
V137I |
possibly damaging |
Het |
| Nxpe5 |
T |
A |
5: 138,228,795 (GRCm39) |
L4Q |
possibly damaging |
Het |
| Obscn |
A |
G |
11: 58,977,496 (GRCm39) |
V2052A |
possibly damaging |
Het |
| Oc90 |
A |
T |
15: 65,753,408 (GRCm39) |
Y304N |
probably damaging |
Het |
| Or13f5 |
T |
C |
4: 52,826,138 (GRCm39) |
V247A |
probably damaging |
Het |
| Or52d3 |
T |
A |
7: 104,229,180 (GRCm39) |
F109Y |
possibly damaging |
Het |
| Or5p1 |
T |
C |
7: 107,916,677 (GRCm39) |
V192A |
probably benign |
Het |
| Or8b101 |
T |
C |
9: 38,020,036 (GRCm39) |
I13T |
probably damaging |
Het |
| Or8k1 |
T |
A |
2: 86,047,877 (GRCm39) |
H59L |
possibly damaging |
Het |
| Parp10 |
A |
T |
15: 76,127,281 (GRCm39) |
I52N |
probably benign |
Het |
| Pdgfrb |
C |
A |
18: 61,206,315 (GRCm39) |
R608S |
probably damaging |
Het |
| Pecam1 |
A |
G |
11: 106,590,634 (GRCm39) |
C47R |
probably damaging |
Het |
| Pirb |
C |
T |
7: 3,720,602 (GRCm39) |
G299S |
probably benign |
Het |
| Pkhd1l1 |
A |
G |
15: 44,392,801 (GRCm39) |
E1712G |
possibly damaging |
Het |
| Plce1 |
T |
C |
19: 38,757,943 (GRCm39) |
I1958T |
probably damaging |
Het |
| Plch2 |
C |
T |
4: 155,069,092 (GRCm39) |
R1073Q |
probably benign |
Het |
| Pld5 |
A |
C |
1: 176,102,433 (GRCm39) |
I3S |
probably benign |
Het |
| Polr1a |
T |
C |
6: 71,943,385 (GRCm39) |
W1207R |
possibly damaging |
Het |
| Polr2m |
T |
G |
9: 71,391,050 (GRCm39) |
I51L |
possibly damaging |
Het |
| Ppl |
G |
A |
16: 4,922,790 (GRCm39) |
R234C |
probably damaging |
Het |
| Ppp1r42 |
C |
T |
1: 10,069,636 (GRCm39) |
R142H |
probably benign |
Het |
| Prokr1 |
A |
G |
6: 87,558,224 (GRCm39) |
V387A |
probably benign |
Het |
| Prss23 |
A |
T |
7: 89,159,108 (GRCm39) |
Y320* |
probably null |
Het |
| Ptprk |
A |
T |
10: 28,436,050 (GRCm39) |
M804L |
probably damaging |
Het |
| Rdh16f2 |
A |
G |
10: 127,710,823 (GRCm39) |
S147G |
probably benign |
Het |
| Rgs7bp |
T |
C |
13: 105,189,532 (GRCm39) |
H89R |
possibly damaging |
Het |
| Rilpl2 |
G |
T |
5: 124,607,875 (GRCm39) |
T115K |
possibly damaging |
Het |
| Rnf212 |
G |
A |
5: 108,877,334 (GRCm39) |
S153F |
probably damaging |
Het |
| Rnf213 |
A |
G |
11: 119,307,455 (GRCm39) |
D705G |
possibly damaging |
Het |
| Selenbp2 |
A |
G |
3: 94,611,426 (GRCm39) |
N379S |
probably benign |
Het |
| Sema3e |
G |
A |
5: 14,276,654 (GRCm39) |
V312M |
probably damaging |
Het |
| Sh2d5 |
T |
A |
4: 137,985,566 (GRCm39) |
L338Q |
probably damaging |
Het |
| Shank3 |
A |
G |
15: 89,384,402 (GRCm39) |
|
probably benign |
Het |
| Skor2 |
G |
T |
18: 76,948,113 (GRCm39) |
G612C |
probably damaging |
Het |
| Slc22a16 |
A |
G |
10: 40,449,636 (GRCm39) |
Y24C |
probably damaging |
Het |
| Slc4a1ap |
T |
A |
5: 31,688,053 (GRCm39) |
Y312* |
probably null |
Het |
| Slc5a7 |
A |
T |
17: 54,583,827 (GRCm39) |
F488I |
probably benign |
Het |
| Snrnp200 |
A |
G |
2: 127,053,527 (GRCm39) |
D130G |
probably damaging |
Het |
| Sorbs2 |
T |
A |
8: 46,194,652 (GRCm39) |
|
probably benign |
Het |
| Tmem91 |
T |
G |
7: 25,368,803 (GRCm39) |
T161P |
probably damaging |
Het |
| Tpd52l1 |
G |
A |
10: 31,222,697 (GRCm39) |
T99M |
probably damaging |
Het |
| Trps1 |
A |
G |
15: 50,524,073 (GRCm39) |
*1036Q |
probably null |
Het |
| Tshr |
A |
T |
12: 91,504,564 (GRCm39) |
T501S |
probably damaging |
Het |
| Tubgcp3 |
T |
C |
8: 12,721,987 (GRCm39) |
N15S |
probably benign |
Het |
| Unc5b |
A |
G |
10: 60,608,127 (GRCm39) |
S669P |
possibly damaging |
Het |
| Zfp970 |
A |
G |
2: 177,167,146 (GRCm39) |
E240G |
probably damaging |
Het |
|
| Other mutations in Alpk2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00468:Alpk2
|
APN |
18 |
65,438,894 (GRCm39) |
missense |
probably benign |
0.27 |
|
IGL00478:Alpk2
|
APN |
18 |
65,440,297 (GRCm39) |
nonsense |
probably null |
|
|
IGL00898:Alpk2
|
APN |
18 |
65,483,644 (GRCm39) |
missense |
probably benign |
0.29 |
|
IGL00978:Alpk2
|
APN |
18 |
65,424,605 (GRCm39) |
splice site |
probably benign |
|
|
IGL01093:Alpk2
|
APN |
18 |
65,482,400 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01094:Alpk2
|
APN |
18 |
65,439,673 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01109:Alpk2
|
APN |
18 |
65,440,211 (GRCm39) |
missense |
probably benign |
0.09 |
|
IGL01370:Alpk2
|
APN |
18 |
65,483,662 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL01393:Alpk2
|
APN |
18 |
65,440,779 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
IGL01629:Alpk2
|
APN |
18 |
65,433,113 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01872:Alpk2
|
APN |
18 |
65,437,824 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01983:Alpk2
|
APN |
18 |
65,483,753 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02294:Alpk2
|
APN |
18 |
65,439,146 (GRCm39) |
missense |
possibly damaging |
0.45 |
|
IGL02333:Alpk2
|
APN |
18 |
65,482,551 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02493:Alpk2
|
APN |
18 |
65,483,402 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02551:Alpk2
|
APN |
18 |
65,505,822 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02864:Alpk2
|
APN |
18 |
65,440,670 (GRCm39) |
missense |
probably benign |
0.12 |
|
IGL02901:Alpk2
|
APN |
18 |
65,439,482 (GRCm39) |
missense |
probably benign |
|
|
IGL02954:Alpk2
|
APN |
18 |
65,439,207 (GRCm39) |
missense |
probably benign |
|
|
IGL03257:Alpk2
|
APN |
18 |
65,482,945 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03389:Alpk2
|
APN |
18 |
65,437,937 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
3-1:Alpk2
|
UTSW |
18 |
65,437,959 (GRCm39) |
missense |
probably damaging |
0.99 |
|
PIT4131001:Alpk2
|
UTSW |
18 |
65,439,450 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0098:Alpk2
|
UTSW |
18 |
65,482,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0098:Alpk2
|
UTSW |
18 |
65,482,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0414:Alpk2
|
UTSW |
18 |
65,439,230 (GRCm39) |
missense |
probably benign |
0.04 |
|
R0546:Alpk2
|
UTSW |
18 |
65,439,788 (GRCm39) |
missense |
probably benign |
0.05 |
|
R0628:Alpk2
|
UTSW |
18 |
65,440,367 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R0658:Alpk2
|
UTSW |
18 |
65,482,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0731:Alpk2
|
UTSW |
18 |
65,438,461 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0919:Alpk2
|
UTSW |
18 |
65,440,544 (GRCm39) |
missense |
probably benign |
|
|
R1069:Alpk2
|
UTSW |
18 |
65,438,085 (GRCm39) |
missense |
probably benign |
0.25 |
|
R1186:Alpk2
|
UTSW |
18 |
65,427,412 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R1508:Alpk2
|
UTSW |
18 |
65,482,376 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1535:Alpk2
|
UTSW |
18 |
65,483,275 (GRCm39) |
missense |
probably benign |
|
|
R1558:Alpk2
|
UTSW |
18 |
65,483,301 (GRCm39) |
missense |
probably benign |
|
|
R1600:Alpk2
|
UTSW |
18 |
65,511,108 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1664:Alpk2
|
UTSW |
18 |
65,482,944 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1672:Alpk2
|
UTSW |
18 |
65,414,030 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1829:Alpk2
|
UTSW |
18 |
65,427,165 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R2110:Alpk2
|
UTSW |
18 |
65,440,151 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R2111:Alpk2
|
UTSW |
18 |
65,482,845 (GRCm39) |
missense |
probably benign |
|
|
R2113:Alpk2
|
UTSW |
18 |
65,438,754 (GRCm39) |
missense |
probably benign |
0.31 |
|
R2126:Alpk2
|
UTSW |
18 |
65,483,439 (GRCm39) |
nonsense |
probably null |
|
|
R2198:Alpk2
|
UTSW |
18 |
65,483,255 (GRCm39) |
missense |
probably benign |
0.42 |
|
R2227:Alpk2
|
UTSW |
18 |
65,511,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2245:Alpk2
|
UTSW |
18 |
65,438,234 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2282:Alpk2
|
UTSW |
18 |
65,440,697 (GRCm39) |
missense |
probably benign |
|
|
R2421:Alpk2
|
UTSW |
18 |
65,439,687 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2512:Alpk2
|
UTSW |
18 |
65,483,591 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3105:Alpk2
|
UTSW |
18 |
65,483,281 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R3700:Alpk2
|
UTSW |
18 |
65,438,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4205:Alpk2
|
UTSW |
18 |
65,438,282 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R4239:Alpk2
|
UTSW |
18 |
65,433,212 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4353:Alpk2
|
UTSW |
18 |
65,424,523 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4572:Alpk2
|
UTSW |
18 |
65,414,075 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4584:Alpk2
|
UTSW |
18 |
65,440,035 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4591:Alpk2
|
UTSW |
18 |
65,438,894 (GRCm39) |
missense |
probably benign |
0.27 |
|
R4595:Alpk2
|
UTSW |
18 |
65,422,819 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4648:Alpk2
|
UTSW |
18 |
65,482,953 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4815:Alpk2
|
UTSW |
18 |
65,483,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4910:Alpk2
|
UTSW |
18 |
65,399,357 (GRCm39) |
nonsense |
probably null |
|
|
R5042:Alpk2
|
UTSW |
18 |
65,483,579 (GRCm39) |
nonsense |
probably null |
|
|
R5295:Alpk2
|
UTSW |
18 |
65,438,109 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5375:Alpk2
|
UTSW |
18 |
65,505,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5475:Alpk2
|
UTSW |
18 |
65,440,083 (GRCm39) |
missense |
probably benign |
0.16 |
|
R5480:Alpk2
|
UTSW |
18 |
65,482,979 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5486:Alpk2
|
UTSW |
18 |
65,427,425 (GRCm39) |
splice site |
probably null |
|
|
R5503:Alpk2
|
UTSW |
18 |
65,439,312 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5595:Alpk2
|
UTSW |
18 |
65,399,319 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5648:Alpk2
|
UTSW |
18 |
65,482,988 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5714:Alpk2
|
UTSW |
18 |
65,438,532 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R5862:Alpk2
|
UTSW |
18 |
65,440,360 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5894:Alpk2
|
UTSW |
18 |
65,414,143 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5898:Alpk2
|
UTSW |
18 |
65,440,694 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5936:Alpk2
|
UTSW |
18 |
65,483,591 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6142:Alpk2
|
UTSW |
18 |
65,438,456 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6291:Alpk2
|
UTSW |
18 |
65,438,972 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6339:Alpk2
|
UTSW |
18 |
65,482,877 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6407:Alpk2
|
UTSW |
18 |
65,422,809 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6487:Alpk2
|
UTSW |
18 |
65,399,254 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R6667:Alpk2
|
UTSW |
18 |
65,440,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6786:Alpk2
|
UTSW |
18 |
65,439,705 (GRCm39) |
missense |
probably benign |
|
|
R6833:Alpk2
|
UTSW |
18 |
65,439,480 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6984:Alpk2
|
UTSW |
18 |
65,438,749 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6999:Alpk2
|
UTSW |
18 |
65,437,584 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7157:Alpk2
|
UTSW |
18 |
65,399,348 (GRCm39) |
nonsense |
probably null |
|
|
R7167:Alpk2
|
UTSW |
18 |
65,440,049 (GRCm39) |
missense |
probably benign |
0.40 |
|
R7225:Alpk2
|
UTSW |
18 |
65,438,270 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7409:Alpk2
|
UTSW |
18 |
65,440,023 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7533:Alpk2
|
UTSW |
18 |
65,437,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7576:Alpk2
|
UTSW |
18 |
65,439,887 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7589:Alpk2
|
UTSW |
18 |
65,433,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7598:Alpk2
|
UTSW |
18 |
65,437,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7664:Alpk2
|
UTSW |
18 |
65,440,073 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7711:Alpk2
|
UTSW |
18 |
65,439,555 (GRCm39) |
missense |
probably benign |
|
|
R7722:Alpk2
|
UTSW |
18 |
65,483,228 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7783:Alpk2
|
UTSW |
18 |
65,439,325 (GRCm39) |
nonsense |
probably null |
|
|
R7806:Alpk2
|
UTSW |
18 |
65,482,487 (GRCm39) |
missense |
probably benign |
|
|
R7953:Alpk2
|
UTSW |
18 |
65,482,901 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8024:Alpk2
|
UTSW |
18 |
65,438,106 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8043:Alpk2
|
UTSW |
18 |
65,482,901 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8063:Alpk2
|
UTSW |
18 |
65,483,417 (GRCm39) |
missense |
probably benign |
0.15 |
|
R8171:Alpk2
|
UTSW |
18 |
65,439,054 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8280:Alpk2
|
UTSW |
18 |
65,440,274 (GRCm39) |
missense |
probably benign |
|
|
R8383:Alpk2
|
UTSW |
18 |
65,438,469 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8414:Alpk2
|
UTSW |
18 |
65,440,542 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8791:Alpk2
|
UTSW |
18 |
65,438,597 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8872:Alpk2
|
UTSW |
18 |
65,413,977 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9352:Alpk2
|
UTSW |
18 |
65,439,783 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9449:Alpk2
|
UTSW |
18 |
65,424,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9525:Alpk2
|
UTSW |
18 |
65,399,288 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9564:Alpk2
|
UTSW |
18 |
65,439,014 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9710:Alpk2
|
UTSW |
18 |
65,482,646 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0023:Alpk2
|
UTSW |
18 |
65,424,471 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0027:Alpk2
|
UTSW |
18 |
65,440,542 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
X0063:Alpk2
|
UTSW |
18 |
65,440,434 (GRCm39) |
missense |
probably benign |
|
|
X0064:Alpk2
|
UTSW |
18 |
65,482,755 (GRCm39) |
missense |
probably benign |
0.09 |
|
Z1176:Alpk2
|
UTSW |
18 |
65,438,682 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTTCGCAAGTACCCCGACAG -3'
(R):5'- AGGCACTCTAGATCTCCTCC -3'
Sequencing Primer
(F):5'- CCGACAGCACTGGAATATGTATTTTG -3'
(R):5'- GCACTCTAGATCTCCTCCCCAAAG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation