Incidental Mutation 'R4831:Ralgapa2'
| ID |
372790 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ralgapa2
|
| Ensembl Gene |
ENSMUSG00000037110 |
| Gene Name |
Ral GTPase activating protein, alpha subunit 2 (catalytic) |
| Synonyms |
AS250, A230067G21Rik, RGC2 |
| MMRRC Submission |
042447-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.250)
|
| Stock # |
R4831 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
146081799-146354264 bp(-) (GRCm39) |
| Type of Mutation |
intron |
| DNA Base Change (assembly) |
A to G
at 146246987 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000153734
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000109986]
[ENSMUST00000131824]
[ENSMUST00000228797]
|
| AlphaFold |
A3KGS3 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000109986
|
| SMART Domains |
Protein: ENSMUSP00000105613
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
1017 |
1028 |
N/A |
INTRINSIC |
|
low complexity region
|
1296 |
1301 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1701 |
1877 |
6.8e-48 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131824
|
| SMART Domains |
Protein: ENSMUSP00000122039
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
469 |
480 |
N/A |
INTRINSIC |
|
low complexity region
|
979 |
990 |
N/A |
INTRINSIC |
|
low complexity region
|
1258 |
1263 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1663 |
1842 |
1.3e-66 |
PFAM |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000146024
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000148784
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000149499
|
| SMART Domains |
Protein: ENSMUSP00000122017
Gene: ENSMUSG00000037110
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
140 |
151 |
N/A |
INTRINSIC |
|
low complexity region
|
650 |
661 |
N/A |
INTRINSIC |
|
low complexity region
|
929 |
934 |
N/A |
INTRINSIC |
|
Pfam:Rap_GAP
|
1334 |
1511 |
2.4e-48 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000228797
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.3%
|
| Validation Efficiency |
99% (96/97) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele exhibit increased incidence and severity of induced urothelial bladder tumors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2810408A11Rik |
C |
T |
11: 69,791,403 (GRCm39) |
V59I |
possibly damaging |
Het |
| 4930544M13Rik |
T |
G |
13: 114,744,183 (GRCm39) |
|
noncoding transcript |
Het |
| Abca13 |
A |
T |
11: 9,492,077 (GRCm39) |
K4373* |
probably null |
Het |
| Abtb2 |
A |
T |
2: 103,513,820 (GRCm39) |
T410S |
probably benign |
Het |
| Adamts13 |
T |
C |
2: 26,873,142 (GRCm39) |
|
probably null |
Het |
| Ahnak2 |
C |
G |
12: 112,742,183 (GRCm39) |
D630H |
probably damaging |
Het |
| Aox3 |
T |
C |
1: 58,191,725 (GRCm39) |
S426P |
probably damaging |
Het |
| Atxn10 |
C |
T |
15: 85,271,260 (GRCm39) |
S266F |
probably benign |
Het |
| B4galnt4 |
G |
T |
7: 140,647,634 (GRCm39) |
M407I |
probably damaging |
Het |
| B4galnt4 |
T |
A |
7: 140,644,470 (GRCm39) |
|
probably null |
Het |
| Bclaf1 |
T |
A |
10: 20,197,872 (GRCm39) |
|
probably benign |
Het |
| C4b |
C |
T |
17: 34,955,864 (GRCm39) |
|
probably null |
Het |
| Cdc42bpg |
T |
C |
19: 6,361,365 (GRCm39) |
F297S |
probably damaging |
Het |
| Cdh10 |
A |
T |
15: 19,013,664 (GRCm39) |
T755S |
probably benign |
Het |
| Ceacam12 |
T |
A |
7: 17,811,305 (GRCm39) |
|
probably null |
Het |
| Cfap65 |
C |
A |
1: 74,956,454 (GRCm39) |
V1042F |
possibly damaging |
Het |
| Cfap77 |
T |
C |
2: 28,875,844 (GRCm39) |
I89V |
probably benign |
Het |
| Cfh |
T |
C |
1: 140,014,125 (GRCm39) |
D688G |
probably benign |
Het |
| Clip1 |
C |
G |
5: 123,721,664 (GRCm39) |
A1182P |
probably damaging |
Het |
| Cyp2b10 |
T |
A |
7: 25,614,921 (GRCm39) |
Y309* |
probably null |
Het |
| Dcaf5 |
T |
C |
12: 80,385,858 (GRCm39) |
E756G |
probably benign |
Het |
| Dctn1 |
A |
T |
6: 83,176,753 (GRCm39) |
Q1231L |
possibly damaging |
Het |
| Dennd1c |
T |
A |
17: 57,373,428 (GRCm39) |
R682* |
probably null |
Het |
| Eml6 |
C |
A |
11: 29,727,052 (GRCm39) |
E1319* |
probably null |
Het |
| Erap1 |
T |
C |
13: 74,838,766 (GRCm39) |
I904T |
probably damaging |
Het |
| Eri1 |
A |
T |
8: 35,943,673 (GRCm39) |
I207N |
possibly damaging |
Het |
| Farp1 |
G |
A |
14: 121,514,469 (GRCm39) |
A933T |
probably damaging |
Het |
| Fcna |
T |
A |
2: 25,515,353 (GRCm39) |
Q210L |
probably benign |
Het |
| Fhad1 |
A |
T |
4: 141,643,378 (GRCm39) |
|
probably null |
Het |
| Fut8 |
T |
G |
12: 77,440,603 (GRCm39) |
Y197D |
probably damaging |
Het |
| Garem1 |
G |
A |
18: 21,262,825 (GRCm39) |
T663I |
probably benign |
Het |
| Gfm2 |
T |
C |
13: 97,301,546 (GRCm39) |
S450P |
probably damaging |
Het |
| Gstk1 |
T |
G |
6: 42,222,938 (GRCm39) |
|
probably benign |
Het |
| Helz2 |
C |
T |
2: 180,879,210 (GRCm39) |
A803T |
probably damaging |
Het |
| Igsf9 |
T |
A |
1: 172,319,455 (GRCm39) |
I280N |
probably damaging |
Het |
| Klhl10 |
A |
G |
11: 100,336,669 (GRCm39) |
K219E |
probably benign |
Het |
| L3mbtl4 |
T |
A |
17: 68,768,558 (GRCm39) |
V222D |
probably damaging |
Het |
| Lrrc9 |
A |
T |
12: 72,546,453 (GRCm39) |
N1214Y |
probably damaging |
Het |
| Ltbp2 |
C |
T |
12: 84,840,414 (GRCm39) |
E1051K |
possibly damaging |
Het |
| Mettl17 |
T |
C |
14: 52,122,440 (GRCm39) |
F13S |
probably benign |
Het |
| Mettl24 |
C |
A |
10: 40,559,413 (GRCm39) |
A21D |
possibly damaging |
Het |
| Mfsd6l |
T |
A |
11: 68,447,331 (GRCm39) |
C61S |
probably benign |
Het |
| Mob4 |
T |
G |
1: 55,191,899 (GRCm39) |
D204E |
probably benign |
Het |
| Mtus1 |
C |
G |
8: 41,536,189 (GRCm39) |
R509T |
probably damaging |
Het |
| Nlrp4a |
T |
A |
7: 26,149,844 (GRCm39) |
F484I |
possibly damaging |
Het |
| Nsrp1 |
T |
C |
11: 76,941,444 (GRCm39) |
N88S |
probably benign |
Het |
| Odad2 |
G |
T |
18: 7,222,564 (GRCm39) |
H568Q |
possibly damaging |
Het |
| Or10d5 |
C |
T |
9: 39,861,408 (GRCm39) |
V220I |
probably benign |
Het |
| Or2g25 |
T |
A |
17: 37,970,969 (GRCm39) |
H85L |
probably benign |
Het |
| Or51b6b |
T |
C |
7: 103,309,678 (GRCm39) |
T260A |
probably benign |
Het |
| Or6c2 |
T |
A |
10: 129,362,449 (GRCm39) |
Y118N |
probably damaging |
Het |
| Parg |
A |
G |
14: 31,924,408 (GRCm39) |
N69S |
probably benign |
Het |
| Pcdh9 |
A |
C |
14: 94,125,377 (GRCm39) |
N264K |
probably damaging |
Het |
| Pcdhb22 |
G |
T |
18: 37,653,615 (GRCm39) |
L694F |
probably damaging |
Het |
| Pcnt |
T |
C |
10: 76,248,335 (GRCm39) |
E928G |
probably damaging |
Het |
| Pdzk1 |
G |
A |
3: 96,775,751 (GRCm39) |
G373D |
probably benign |
Het |
| Pea15a |
A |
G |
1: 172,026,740 (GRCm39) |
I89T |
probably damaging |
Het |
| Phc1 |
T |
A |
6: 122,313,964 (GRCm39) |
|
probably benign |
Het |
| Pikfyve |
T |
A |
1: 65,235,900 (GRCm39) |
C191S |
probably damaging |
Het |
| Pitpnm1 |
T |
A |
19: 4,158,130 (GRCm39) |
D573E |
probably damaging |
Het |
| Pld5 |
A |
G |
1: 176,102,450 (GRCm39) |
|
probably benign |
Het |
| Plscr2 |
A |
T |
9: 92,173,130 (GRCm39) |
N89I |
possibly damaging |
Het |
| Pm20d2 |
A |
C |
4: 33,179,293 (GRCm39) |
N315K |
probably damaging |
Het |
| Pnpla1 |
T |
A |
17: 29,097,518 (GRCm39) |
M228K |
probably benign |
Het |
| Prim2 |
T |
C |
1: 33,709,217 (GRCm39) |
|
probably benign |
Het |
| Rgs22 |
G |
T |
15: 36,050,294 (GRCm39) |
H719N |
probably benign |
Het |
| Ror2 |
C |
T |
13: 53,272,880 (GRCm39) |
D250N |
probably damaging |
Het |
| Saal1 |
A |
G |
7: 46,349,071 (GRCm39) |
V281A |
probably benign |
Het |
| Selenof |
A |
T |
3: 144,296,411 (GRCm39) |
K94N |
probably damaging |
Het |
| Slamf9 |
T |
A |
1: 172,304,831 (GRCm39) |
C148* |
probably null |
Het |
| Slc4a7 |
T |
C |
14: 14,772,699 (GRCm38) |
|
probably null |
Het |
| Slco1a5 |
A |
G |
6: 142,180,431 (GRCm39) |
I657T |
probably benign |
Het |
| St3gal2 |
A |
T |
8: 111,684,480 (GRCm39) |
H46L |
probably benign |
Het |
| Sucnr1 |
T |
G |
3: 59,994,069 (GRCm39) |
M199R |
probably damaging |
Het |
| Taok1 |
T |
A |
11: 77,444,500 (GRCm39) |
E525V |
probably null |
Het |
| Tbc1d10c |
T |
A |
19: 4,235,445 (GRCm39) |
E298V |
probably damaging |
Het |
| Tll2 |
T |
A |
19: 41,118,951 (GRCm39) |
H259L |
probably damaging |
Het |
| Tpcn1 |
A |
T |
5: 120,691,554 (GRCm39) |
F300Y |
probably damaging |
Het |
| Uba6 |
T |
A |
5: 86,279,197 (GRCm39) |
I642L |
probably benign |
Het |
| Ubqln5 |
T |
A |
7: 103,778,829 (GRCm39) |
|
probably benign |
Het |
| Vmn1r27 |
A |
T |
6: 58,192,827 (GRCm39) |
L9Q |
possibly damaging |
Het |
| Vmn2r100 |
C |
T |
17: 19,741,672 (GRCm39) |
T128I |
probably benign |
Het |
| Vmn2r109 |
C |
T |
17: 20,761,494 (GRCm39) |
G621D |
probably benign |
Het |
| Vmn2r49 |
C |
T |
7: 9,720,352 (GRCm39) |
D380N |
probably benign |
Het |
| Vps13a |
C |
T |
19: 16,655,356 (GRCm39) |
V1891I |
probably benign |
Het |
| Wbp2 |
G |
T |
11: 115,971,463 (GRCm39) |
Y147* |
probably null |
Het |
| Wdr46 |
T |
A |
17: 34,160,810 (GRCm39) |
N191K |
probably benign |
Het |
| Wdr46 |
T |
C |
17: 34,168,373 (GRCm39) |
|
probably benign |
Het |
| Wnt2 |
A |
C |
6: 18,023,285 (GRCm39) |
F121L |
probably benign |
Het |
| Xpnpep1 |
T |
A |
19: 53,003,053 (GRCm39) |
D100V |
probably benign |
Het |
| Xpo4 |
T |
C |
14: 57,827,559 (GRCm39) |
Y879C |
probably damaging |
Het |
| Zswim4 |
A |
T |
8: 84,938,948 (GRCm39) |
V978D |
probably damaging |
Het |
|
| Other mutations in Ralgapa2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00666:Ralgapa2
|
APN |
2 |
146,327,056 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
IGL00915:Ralgapa2
|
APN |
2 |
146,184,442 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01012:Ralgapa2
|
APN |
2 |
146,263,659 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL01018:Ralgapa2
|
APN |
2 |
146,252,112 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01018:Ralgapa2
|
APN |
2 |
146,252,113 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL01902:Ralgapa2
|
APN |
2 |
146,156,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02160:Ralgapa2
|
APN |
2 |
146,190,360 (GRCm39) |
splice site |
probably benign |
|
|
IGL02321:Ralgapa2
|
APN |
2 |
146,254,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02412:Ralgapa2
|
APN |
2 |
146,254,052 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL03026:Ralgapa2
|
APN |
2 |
146,302,695 (GRCm39) |
splice site |
probably benign |
|
|
IGL03115:Ralgapa2
|
APN |
2 |
146,266,734 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03256:Ralgapa2
|
APN |
2 |
146,302,632 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL03379:Ralgapa2
|
APN |
2 |
146,199,907 (GRCm39) |
missense |
probably benign |
0.01 |
|
Chow
|
UTSW |
2 |
146,188,638 (GRCm39) |
nonsense |
probably null |
|
|
purina
|
UTSW |
2 |
146,175,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
P4748:Ralgapa2
|
UTSW |
2 |
146,188,731 (GRCm39) |
nonsense |
probably null |
|
|
R0012:Ralgapa2
|
UTSW |
2 |
146,254,672 (GRCm39) |
missense |
probably benign |
|
|
R0012:Ralgapa2
|
UTSW |
2 |
146,254,672 (GRCm39) |
missense |
probably benign |
|
|
R0165:Ralgapa2
|
UTSW |
2 |
146,230,407 (GRCm39) |
splice site |
probably benign |
|
|
R0344:Ralgapa2
|
UTSW |
2 |
146,188,714 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0402:Ralgapa2
|
UTSW |
2 |
146,276,729 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0419:Ralgapa2
|
UTSW |
2 |
146,270,592 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R0638:Ralgapa2
|
UTSW |
2 |
146,184,112 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0704:Ralgapa2
|
UTSW |
2 |
146,293,704 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0722:Ralgapa2
|
UTSW |
2 |
146,230,451 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0866:Ralgapa2
|
UTSW |
2 |
146,277,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1065:Ralgapa2
|
UTSW |
2 |
146,292,478 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1212:Ralgapa2
|
UTSW |
2 |
146,199,902 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1395:Ralgapa2
|
UTSW |
2 |
146,230,420 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1614:Ralgapa2
|
UTSW |
2 |
146,230,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1686:Ralgapa2
|
UTSW |
2 |
146,199,920 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1799:Ralgapa2
|
UTSW |
2 |
146,184,648 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1905:Ralgapa2
|
UTSW |
2 |
146,229,621 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1956:Ralgapa2
|
UTSW |
2 |
146,302,679 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2144:Ralgapa2
|
UTSW |
2 |
146,230,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2148:Ralgapa2
|
UTSW |
2 |
146,273,807 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2219:Ralgapa2
|
UTSW |
2 |
146,263,599 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2220:Ralgapa2
|
UTSW |
2 |
146,263,599 (GRCm39) |
missense |
probably benign |
0.09 |
|
R2261:Ralgapa2
|
UTSW |
2 |
146,184,603 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2402:Ralgapa2
|
UTSW |
2 |
146,195,112 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2495:Ralgapa2
|
UTSW |
2 |
146,203,320 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R3752:Ralgapa2
|
UTSW |
2 |
146,263,551 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3953:Ralgapa2
|
UTSW |
2 |
146,277,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3956:Ralgapa2
|
UTSW |
2 |
146,277,884 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4177:Ralgapa2
|
UTSW |
2 |
146,327,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4182:Ralgapa2
|
UTSW |
2 |
146,277,914 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4193:Ralgapa2
|
UTSW |
2 |
146,184,493 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4332:Ralgapa2
|
UTSW |
2 |
146,102,288 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4507:Ralgapa2
|
UTSW |
2 |
146,195,168 (GRCm39) |
missense |
probably benign |
0.11 |
|
R4574:Ralgapa2
|
UTSW |
2 |
146,277,919 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4585:Ralgapa2
|
UTSW |
2 |
146,156,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4627:Ralgapa2
|
UTSW |
2 |
146,203,373 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R4647:Ralgapa2
|
UTSW |
2 |
146,229,549 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4677:Ralgapa2
|
UTSW |
2 |
146,187,387 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4724:Ralgapa2
|
UTSW |
2 |
146,187,453 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4760:Ralgapa2
|
UTSW |
2 |
146,188,669 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4962:Ralgapa2
|
UTSW |
2 |
146,276,754 (GRCm39) |
nonsense |
probably null |
|
|
R4993:Ralgapa2
|
UTSW |
2 |
146,289,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5041:Ralgapa2
|
UTSW |
2 |
146,327,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5120:Ralgapa2
|
UTSW |
2 |
146,254,004 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5185:Ralgapa2
|
UTSW |
2 |
146,230,406 (GRCm39) |
splice site |
probably null |
|
|
R5393:Ralgapa2
|
UTSW |
2 |
146,187,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5428:Ralgapa2
|
UTSW |
2 |
146,176,414 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5439:Ralgapa2
|
UTSW |
2 |
146,184,430 (GRCm39) |
missense |
probably benign |
0.08 |
|
R5476:Ralgapa2
|
UTSW |
2 |
146,289,356 (GRCm39) |
missense |
probably benign |
|
|
R5695:Ralgapa2
|
UTSW |
2 |
146,175,397 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5705:Ralgapa2
|
UTSW |
2 |
146,291,193 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5718:Ralgapa2
|
UTSW |
2 |
146,295,326 (GRCm39) |
splice site |
probably null |
|
|
R5817:Ralgapa2
|
UTSW |
2 |
146,175,406 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Ralgapa2
|
UTSW |
2 |
146,230,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5994:Ralgapa2
|
UTSW |
2 |
146,203,373 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6048:Ralgapa2
|
UTSW |
2 |
146,276,765 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6158:Ralgapa2
|
UTSW |
2 |
146,266,596 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R6169:Ralgapa2
|
UTSW |
2 |
146,292,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6280:Ralgapa2
|
UTSW |
2 |
146,184,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6301:Ralgapa2
|
UTSW |
2 |
146,169,331 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6650:Ralgapa2
|
UTSW |
2 |
146,230,422 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6959:Ralgapa2
|
UTSW |
2 |
146,184,621 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7020:Ralgapa2
|
UTSW |
2 |
146,188,638 (GRCm39) |
nonsense |
probably null |
|
|
R7035:Ralgapa2
|
UTSW |
2 |
146,353,777 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7167:Ralgapa2
|
UTSW |
2 |
146,190,374 (GRCm39) |
missense |
probably benign |
|
|
R7186:Ralgapa2
|
UTSW |
2 |
146,230,406 (GRCm39) |
splice site |
probably null |
|
|
R7252:Ralgapa2
|
UTSW |
2 |
146,184,671 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7266:Ralgapa2
|
UTSW |
2 |
146,176,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7371:Ralgapa2
|
UTSW |
2 |
146,189,046 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7432:Ralgapa2
|
UTSW |
2 |
146,276,776 (GRCm39) |
missense |
probably benign |
0.41 |
|
R7470:Ralgapa2
|
UTSW |
2 |
146,266,587 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7663:Ralgapa2
|
UTSW |
2 |
146,260,335 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7780:Ralgapa2
|
UTSW |
2 |
146,184,334 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7973:Ralgapa2
|
UTSW |
2 |
146,230,481 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8018:Ralgapa2
|
UTSW |
2 |
146,182,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8063:Ralgapa2
|
UTSW |
2 |
146,285,775 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8070:Ralgapa2
|
UTSW |
2 |
146,195,199 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8264:Ralgapa2
|
UTSW |
2 |
146,175,370 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8309:Ralgapa2
|
UTSW |
2 |
146,246,786 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8409:Ralgapa2
|
UTSW |
2 |
146,086,897 (GRCm39) |
missense |
|
|
|
R8474:Ralgapa2
|
UTSW |
2 |
146,266,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8487:Ralgapa2
|
UTSW |
2 |
146,230,463 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8492:Ralgapa2
|
UTSW |
2 |
146,184,524 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R8733:Ralgapa2
|
UTSW |
2 |
146,266,683 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8856:Ralgapa2
|
UTSW |
2 |
146,184,139 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8858:Ralgapa2
|
UTSW |
2 |
146,102,285 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8862:Ralgapa2
|
UTSW |
2 |
146,266,731 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9146:Ralgapa2
|
UTSW |
2 |
146,184,252 (GRCm39) |
missense |
probably benign |
|
|
R9324:Ralgapa2
|
UTSW |
2 |
146,302,645 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9439:Ralgapa2
|
UTSW |
2 |
146,254,058 (GRCm39) |
missense |
probably benign |
|
|
R9457:Ralgapa2
|
UTSW |
2 |
146,176,474 (GRCm39) |
missense |
probably damaging |
0.99 |
|
RF019:Ralgapa2
|
UTSW |
2 |
146,203,423 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
X0019:Ralgapa2
|
UTSW |
2 |
146,230,572 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
Z1088:Ralgapa2
|
UTSW |
2 |
146,276,825 (GRCm39) |
missense |
probably benign |
0.20 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTCAGTTGTAACCAGTGGCG -3'
(R):5'- TTGGAACTCATGGAATAACTGAGC -3'
Sequencing Primer
(F):5'- TAACCAGTGGCGGGCATCAG -3'
(R):5'- AAAGCCTATTAATGCCTCACTCTTGG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation