Mutagenetix > Incidental Mutation

Incidental Mutation 'R4856:Fat3'

373970

Institutional Source

Beutler Lab

Gene Symbol

Fat3

Ensembl Gene

ENSMUSG00000074505

Gene Name

FAT atypical cadherin 3

Synonyms

D430038H04Rik, LOC382129, LOC234973, 9430076A06Rik

MMRRC Submission

042467-MU

Accession Numbers

Essential gene?

Possibly essential (E-score: 0.714) question?

Stock #

R4856 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

15821485-16412581 bp(-) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 15932626 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Phenylalanine at position 1436 (I1436F)

Ref Sequence

ENSEMBL: ENSMUSP00000148968 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000082170] [ENSMUST00000217308]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000082170
AA Change: I1436F

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000080808
Gene: ENSMUSG00000074505
AA Change: I1436F

Domain	Start	End	E-Value	Type
signal peptide	1	27	N/A	INTRINSIC
CA	65	151	3e-7	SMART
CA	175	259	8.9e-22	SMART
CA	280	368	8.9e-4	SMART
CA	389	465	2.6e-11	SMART
CA	489	571	2e-29	SMART
low complexity region	684	697	N/A	INTRINSIC
CA	743	824	1e-24	SMART
low complexity region	830	840	N/A	INTRINSIC
CA	848	929	7.6e-26	SMART
CA	953	1034	1.5e-25	SMART
CA	1060	1141	6.6e-32	SMART
CA	1165	1247	1.5e-30	SMART
CA	1273	1349	1.8e-8	SMART
CA	1375	1453	2.9e-12	SMART
CA	1477	1559	3e-22	SMART
CA	1583	1664	3.1e-16	SMART
CA	1688	1762	4.2e-22	SMART
CA	1793	1876	2.5e-26	SMART
CA	1900	1975	1.5e-8	SMART
low complexity region	1983	1994	N/A	INTRINSIC
CA	1999	2077	1.4e-18	SMART
CA	2101	2179	6.6e-10	SMART
CA	2203	2280	4.9e-19	SMART
CA	2304	2387	4.3e-29	SMART
CA	2411	2489	4.2e-11	SMART
CA	2513	2593	2.8e-22	SMART
CA	2617	2701	4.3e-10	SMART
CA	2719	2807	2.5e-7	SMART
CA	2831	2917	3.3e-27	SMART
CA	2941	3022	9.4e-23	SMART
CA	3046	3124	2.4e-26	SMART
CA	3148	3229	1.3e-32	SMART
CA	3253	3334	1.3e-29	SMART
CA	3358	3439	4.9e-28	SMART
CA	3463	3544	6.4e-12	SMART
EGF	3793	3828	1.3e-1	SMART
LamG	3852	3989	4.3e-25	SMART
EGF	4019	4053	2.7e-6	SMART
EGF	4058	4091	4.5e-6	SMART
EGF_CA	4093	4129	3.9e-11	SMART
transmembrane domain	4151	4170	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000217308
AA Change: I1436F

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

Coding Region Coverage

1x: 99.1%
3x: 98.4%
10x: 96.4%
20x: 92.8%

Validation Efficiency

MGI Phenotype

PHENOTYPE: Mice homozgyous for a knock-out allele exhibit abnormal amacrine cell differentiation and migration that result in the formation of two additional plexiform layers and thickened retinal ganglion layer. [provided by MGI curators]

Allele List at MGI

All alleles(3) : Gene trapped(3)

Other mutations in this stock

Total: 85 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aebp2	G	A	6: 140,589,799 (GRCm39)		probably null	Het
Arsi	G	A	18: 61,049,723 (GRCm39)	G202E	probably benign	Het
Atp2b4	T	A	1: 133,634,518 (GRCm39)	I1177L	probably benign	Het
Bub3	A	T	7: 131,163,297 (GRCm39)	D76V	probably damaging	Het
Cacna2d4	G	A	6: 119,255,217 (GRCm39)	R578Q	possibly damaging	Het
Caprin2	A	C	6: 148,774,509 (GRCm39)	S268A	probably benign	Het
Card6	T	C	15: 5,134,623 (GRCm39)		probably null	Het
Cdk13	A	G	13: 17,894,319 (GRCm39)	S1103P	probably benign	Het
Cfap221	T	C	1: 119,861,934 (GRCm39)	T614A	probably damaging	Het
Cfap221	T	A	1: 119,912,488 (GRCm39)	Y133F	probably damaging	Het
Clcc1	A	G	3: 108,584,154 (GRCm39)	T513A	probably benign	Het
Clec4g	T	A	8: 3,766,419 (GRCm39)		probably benign	Het
Cntln	A	C	4: 84,889,466 (GRCm39)	E316D	probably benign	Het
Cpne2	T	A	8: 95,290,592 (GRCm39)	D392E	probably benign	Het
Cry1	G	T	10: 84,984,634 (GRCm39)	P147T	probably damaging	Het
Cyp4a29	T	C	4: 115,110,078 (GRCm39)	V440A	probably benign	Het
Ddx46	A	G	13: 55,786,012 (GRCm39)	D64G	unknown	Het
Dhx34	A	G	7: 15,949,367 (GRCm39)	S354P	possibly damaging	Het
Ecm2	A	T	13: 49,676,263 (GRCm39)	I327F	possibly damaging	Het
Elavl3	T	C	9: 21,937,614 (GRCm39)	K189E	possibly damaging	Het
Enam	A	T	5: 88,636,593 (GRCm39)	R82*	probably null	Het
Erf	A	G	7: 24,945,636 (GRCm39)	V45A	probably damaging	Het
Flnc	T	C	6: 29,447,889 (GRCm39)	Y1231H	probably damaging	Het
Ggta1	T	A	2: 35,292,803 (GRCm39)	H180L	possibly damaging	Het
Grin2c	T	C	11: 115,151,616 (GRCm39)	T115A	probably damaging	Het
H6pd	C	T	4: 150,067,235 (GRCm39)	V384M	possibly damaging	Het
Hba-x	A	G	11: 32,227,008 (GRCm39)	E39G	probably benign	Het
Hnrnpul2	C	T	19: 8,807,191 (GRCm39)	P618S	probably benign	Het
Hpse2	C	T	19: 42,777,396 (GRCm39)	R590H	probably damaging	Het
Ighv1-54	C	A	12: 115,157,423 (GRCm39)	G75C	probably damaging	Het
Ighv8-11	C	A	12: 115,530,774 (GRCm39)	R118L	possibly damaging	Het
Iqcm	A	T	8: 76,615,228 (GRCm39)	R436S	possibly damaging	Het
Islr	T	C	9: 58,064,889 (GRCm39)	D206G	probably damaging	Het
Itih1	A	G	14: 30,658,658 (GRCm39)		probably null	Het
Jam2	G	A	16: 84,598,490 (GRCm39)	D34N	probably benign	Het
Klhl14	A	T	18: 21,691,029 (GRCm39)		probably null	Het
Lama2	TTTGCGCATT	TTT	10: 26,919,639 (GRCm39)		probably null	Het
Lrrc66	A	G	5: 73,765,910 (GRCm39)	F378L	probably benign	Het
Map10	T	A	8: 126,397,431 (GRCm39)	Y275N	probably damaging	Het
Mpi	T	C	9: 57,452,590 (GRCm39)	Y314C	probably damaging	Het
Mpp3	A	G	11: 101,915,962 (GRCm39)	Y55H	probably benign	Het
Nectin4	T	C	1: 171,212,383 (GRCm39)	V327A	possibly damaging	Het
Nlrp12	T	A	7: 3,289,072 (GRCm39)	D480V	probably damaging	Het
Nolc1	GAGCAGCAGCAGCAGCAGCAGCAGCAGC	GAGCAGCAGCAGCAGCAGCAGCAGC	19: 46,071,594 (GRCm39)		probably benign	Het
Notch2	A	T	3: 98,009,735 (GRCm39)	Y554F	probably damaging	Het
Nrsn2	T	C	2: 152,211,531 (GRCm39)	K167E	probably benign	Het
Olr1	T	A	6: 129,470,559 (GRCm39)	K203*	probably null	Het
Or14j8	A	T	17: 38,262,962 (GRCm39)	S318T	probably benign	Het
Or2ag13	T	A	7: 106,473,177 (GRCm39)	I92F	probably damaging	Het
Or5b117	T	C	19: 13,431,885 (GRCm39)		probably null	Het
Or8b3	A	T	9: 38,314,764 (GRCm39)	N195I	probably damaging	Het
Or9i2	T	A	19: 13,815,643 (GRCm39)	E298V	probably damaging	Het
Osbpl9	T	C	4: 108,925,564 (GRCm39)	N485S	probably benign	Het
Pbk	T	A	14: 66,052,650 (GRCm39)	H164Q	probably damaging	Het
Pfn2	G	T	3: 57,754,874 (GRCm39)	N10K	probably damaging	Het
Pik3ca	A	G	3: 32,491,312 (GRCm39)	D133G	probably damaging	Het
Pramel27	G	T	4: 143,579,873 (GRCm39)	R486L	probably benign	Het
Prl6a1	A	T	13: 27,502,983 (GRCm39)	D193V	probably damaging	Het
Rad21	G	T	15: 51,831,896 (GRCm39)	P395Q	probably damaging	Het
Reps1	T	A	10: 17,999,373 (GRCm39)	I720N	probably damaging	Het
Rpn2	T	C	2: 157,159,964 (GRCm39)		probably null	Het
Rreb1	G	A	13: 38,115,034 (GRCm39)	V798M	possibly damaging	Het
Sardh	C	T	2: 27,134,489 (GRCm39)	R9H	probably benign	Het
Scgb3a2	C	T	18: 43,899,819 (GRCm39)	P36S	probably damaging	Het
Scn10a	C	A	9: 119,523,375 (GRCm39)	G6V	possibly damaging	Het
Scn10a	C	T	9: 119,523,376 (GRCm39)	G6R	possibly damaging	Het
Scn3a	T	C	2: 65,291,376 (GRCm39)	D1790G	probably damaging	Het
Sec24b	A	T	3: 129,777,619 (GRCm39)	H1226Q	probably benign	Het
Shroom3	G	T	5: 93,090,945 (GRCm39)	V1151F	probably damaging	Het
Slc12a3	G	A	8: 95,078,438 (GRCm39)		probably null	Het
Slitrk6	T	C	14: 110,989,315 (GRCm39)	T131A	probably damaging	Het
Spata1	C	G	3: 146,175,529 (GRCm39)	D326H	probably damaging	Het
Tex52	A	T	6: 128,361,951 (GRCm39)		probably null	Het
Tma16	A	C	8: 66,934,129 (GRCm39)	C75W	probably damaging	Het
Tmem67	G	A	4: 12,089,416 (GRCm39)		probably benign	Het
Trgv4	T	C	13: 19,369,236 (GRCm39)	V29A	probably benign	Het
Trmt10a	A	T	3: 137,854,146 (GRCm39)	K75*	probably null	Het
Ttc3	T	C	16: 94,191,142 (GRCm39)	V228A	probably benign	Het
Ttn	T	C	2: 76,561,644 (GRCm39)	D28954G	probably damaging	Het
Uggt2	A	G	14: 119,273,376 (GRCm39)		probably null	Het
Vars1	T	A	17: 35,234,702 (GRCm39)	V1177E	probably benign	Het
Vmn1r59	T	C	7: 5,457,532 (GRCm39)	D76G	possibly damaging	Het
Vmn2r114	G	T	17: 23,527,008 (GRCm39)	A508E	probably benign	Het
Vps41	G	A	13: 19,013,425 (GRCm39)	V348M	probably damaging	Het
Zbtb43	T	C	2: 33,343,944 (GRCm39)	H427R	probably damaging	Het

Other mutations in Fat3

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00662:Fat3	APN	9	15,907,723 (GRCm39)	missense	possibly damaging	0.77
IGL00962:Fat3	APN	9	15,826,815 (GRCm39)	missense	probably benign	0.14
IGL00966:Fat3	APN	9	15,910,390 (GRCm39)	missense	possibly damaging	0.69
IGL01100:Fat3	APN	9	16,286,524 (GRCm39)	missense	probably damaging	1.00
IGL01104:Fat3	APN	9	16,287,024 (GRCm39)	missense	possibly damaging	0.92
IGL01104:Fat3	APN	9	15,909,756 (GRCm39)	missense	probably damaging	1.00
IGL01121:Fat3	APN	9	15,909,697 (GRCm39)	missense	probably benign	0.00
IGL01407:Fat3	APN	9	16,289,319 (GRCm39)	missense	probably benign	0.01
IGL01444:Fat3	APN	9	15,910,144 (GRCm39)	missense	probably damaging	1.00
IGL01634:Fat3	APN	9	15,909,654 (GRCm39)	missense	probably damaging	1.00
IGL01649:Fat3	APN	9	16,288,015 (GRCm39)	missense	possibly damaging	0.95
IGL01839:Fat3	APN	9	15,909,168 (GRCm39)	missense	probably damaging	1.00
IGL01867:Fat3	APN	9	16,289,197 (GRCm39)	missense	probably benign	0.03
IGL01894:Fat3	APN	9	16,287,145 (GRCm39)	missense	probably benign
IGL01913:Fat3	APN	9	15,910,086 (GRCm39)	missense	probably damaging	0.99
IGL02033:Fat3	APN	9	15,826,648 (GRCm39)	missense	possibly damaging	0.50
IGL02035:Fat3	APN	9	16,289,266 (GRCm39)	missense	probably benign	0.06
IGL02146:Fat3	APN	9	15,910,878 (GRCm39)	missense	probably benign
IGL02147:Fat3	APN	9	15,907,281 (GRCm39)	missense	probably damaging	1.00
IGL02161:Fat3	APN	9	15,908,346 (GRCm39)	missense	probably benign	0.10
IGL02161:Fat3	APN	9	15,908,347 (GRCm39)	nonsense	probably null
IGL02164:Fat3	APN	9	15,942,720 (GRCm39)	splice site	probably benign
IGL02269:Fat3	APN	9	15,826,873 (GRCm39)	missense	possibly damaging	0.84
IGL02314:Fat3	APN	9	15,881,134 (GRCm39)	missense	possibly damaging	0.61
IGL02393:Fat3	APN	9	15,899,708 (GRCm39)	nonsense	probably null
IGL02410:Fat3	APN	9	15,909,141 (GRCm39)	missense	probably damaging	1.00
IGL02504:Fat3	APN	9	15,871,094 (GRCm39)	missense	probably damaging	1.00
IGL02572:Fat3	APN	9	15,871,802 (GRCm39)	missense	probably benign
IGL02623:Fat3	APN	9	15,908,433 (GRCm39)	missense	probably damaging	1.00
IGL02654:Fat3	APN	9	15,908,271 (GRCm39)	missense	possibly damaging	0.84
IGL02749:Fat3	APN	9	15,918,007 (GRCm39)	missense	possibly damaging	0.93
IGL02810:Fat3	APN	9	16,288,146 (GRCm39)	missense	probably damaging	1.00
IGL02839:Fat3	APN	9	15,830,466 (GRCm39)	missense	probably damaging	1.00
IGL02890:Fat3	APN	9	15,826,636 (GRCm39)	missense	probably benign	0.03
IGL02892:Fat3	APN	9	16,288,858 (GRCm39)	missense	probably damaging	1.00
IGL03090:Fat3	APN	9	16,288,535 (GRCm39)	nonsense	probably null
IGL03144:Fat3	APN	9	16,286,541 (GRCm39)	missense	probably damaging	1.00
IGL03199:Fat3	APN	9	16,288,344 (GRCm39)	missense	possibly damaging	0.83
IGL03365:Fat3	APN	9	15,907,765 (GRCm39)	missense	probably damaging	1.00
IGL03392:Fat3	APN	9	15,915,158 (GRCm39)	missense	probably benign
IGL03408:Fat3	APN	9	15,909,253 (GRCm39)	nonsense	probably null
gagged	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
hushed	UTSW	9	15,871,165 (GRCm39)	missense	possibly damaging	0.72
Muffled	UTSW	9	15,849,287 (GRCm39)	critical splice donor site	probably null
muted	UTSW	9	15,908,773 (GRCm39)	missense	possibly damaging	0.93
Softened	UTSW	9	16,289,481 (GRCm39)	missense	probably benign
BB001:Fat3	UTSW	9	15,910,593 (GRCm39)	missense	probably damaging	1.00
BB002:Fat3	UTSW	9	15,942,656 (GRCm39)	missense	possibly damaging	0.77
BB011:Fat3	UTSW	9	15,910,593 (GRCm39)	missense	probably damaging	1.00
BB012:Fat3	UTSW	9	15,942,656 (GRCm39)	missense	possibly damaging	0.77
F6893:Fat3	UTSW	9	15,918,085 (GRCm39)	missense	probably damaging	0.99
IGL03050:Fat3	UTSW	9	15,907,896 (GRCm39)	missense	probably benign	0.04
PIT4142001:Fat3	UTSW	9	15,903,414 (GRCm39)	critical splice donor site	probably null
PIT4283001:Fat3	UTSW	9	15,917,897 (GRCm39)	missense	possibly damaging	0.77
PIT4378001:Fat3	UTSW	9	16,288,104 (GRCm39)	missense	probably benign	0.05
PIT4434001:Fat3	UTSW	9	15,907,612 (GRCm39)	missense	probably benign	0.00
PIT4468001:Fat3	UTSW	9	15,907,647 (GRCm39)	missense	probably benign	0.06
R0001:Fat3	UTSW	9	16,289,169 (GRCm39)	missense	probably damaging	0.99
R0005:Fat3	UTSW	9	15,874,162 (GRCm39)	missense	probably damaging	1.00
R0005:Fat3	UTSW	9	15,874,162 (GRCm39)	missense	probably damaging	1.00
R0038:Fat3	UTSW	9	15,826,306 (GRCm39)	missense	probably damaging	1.00
R0046:Fat3	UTSW	9	15,877,275 (GRCm39)	missense	possibly damaging	0.65
R0089:Fat3	UTSW	9	15,849,501 (GRCm39)	missense	probably benign
R0135:Fat3	UTSW	9	15,918,073 (GRCm39)	missense	probably damaging	1.00
R0255:Fat3	UTSW	9	15,881,002 (GRCm39)	splice site	probably benign
R0349:Fat3	UTSW	9	15,942,476 (GRCm39)	missense	probably damaging	1.00
R0361:Fat3	UTSW	9	15,909,699 (GRCm39)	missense	possibly damaging	0.77
R0382:Fat3	UTSW	9	15,871,052 (GRCm39)	missense	probably damaging	1.00
R0418:Fat3	UTSW	9	16,158,192 (GRCm39)	missense	probably damaging	1.00
R0419:Fat3	UTSW	9	15,903,552 (GRCm39)	missense	probably damaging	1.00
R0437:Fat3	UTSW	9	15,908,228 (GRCm39)	missense	probably damaging	1.00
R0441:Fat3	UTSW	9	15,856,304 (GRCm39)	splice site	probably benign
R0480:Fat3	UTSW	9	15,909,025 (GRCm39)	missense	probably benign	0.00
R0510:Fat3	UTSW	9	15,910,981 (GRCm39)	nonsense	probably null
R0665:Fat3	UTSW	9	15,908,698 (GRCm39)	missense	probably benign
R0715:Fat3	UTSW	9	16,286,419 (GRCm39)	missense	probably benign
R0727:Fat3	UTSW	9	15,907,995 (GRCm39)	missense	probably damaging	1.00
R0882:Fat3	UTSW	9	15,942,664 (GRCm39)	missense	possibly damaging	0.84
R0946:Fat3	UTSW	9	15,909,100 (GRCm39)	missense	possibly damaging	0.95
R1068:Fat3	UTSW	9	15,881,330 (GRCm39)	missense	probably benign
R1081:Fat3	UTSW	9	16,286,580 (GRCm39)	missense	possibly damaging	0.62
R1082:Fat3	UTSW	9	15,917,911 (GRCm39)	missense	probably damaging	1.00
R1148:Fat3	UTSW	9	15,908,070 (GRCm39)	missense	probably damaging	1.00
R1148:Fat3	UTSW	9	15,908,070 (GRCm39)	missense	probably damaging	1.00
R1233:Fat3	UTSW	9	15,834,041 (GRCm39)	missense	probably benign
R1306:Fat3	UTSW	9	16,287,975 (GRCm39)	missense	probably damaging	1.00
R1311:Fat3	UTSW	9	15,932,706 (GRCm39)	missense	probably damaging	1.00
R1338:Fat3	UTSW	9	15,836,387 (GRCm39)	missense	probably benign	0.00
R1395:Fat3	UTSW	9	16,158,212 (GRCm39)	missense	probably benign	0.00
R1466:Fat3	UTSW	9	16,286,778 (GRCm39)	missense	probably damaging	0.96
R1466:Fat3	UTSW	9	16,286,778 (GRCm39)	missense	probably damaging	0.96
R1510:Fat3	UTSW	9	15,871,351 (GRCm39)	missense	probably damaging	1.00
R1528:Fat3	UTSW	9	15,836,387 (GRCm39)	missense	probably benign	0.00
R1531:Fat3	UTSW	9	15,908,761 (GRCm39)	missense	probably damaging	1.00
R1659:Fat3	UTSW	9	15,908,479 (GRCm39)	missense	possibly damaging	0.91
R1697:Fat3	UTSW	9	15,856,176 (GRCm39)	missense	probably benign	0.05
R1699:Fat3	UTSW	9	15,849,694 (GRCm39)	missense	probably damaging	1.00
R1728:Fat3	UTSW	9	15,907,611 (GRCm39)	missense	possibly damaging	0.65
R1729:Fat3	UTSW	9	15,907,611 (GRCm39)	missense	possibly damaging	0.65
R1731:Fat3	UTSW	9	15,907,233 (GRCm39)	missense	probably benign
R1784:Fat3	UTSW	9	15,907,611 (GRCm39)	missense	possibly damaging	0.65
R1789:Fat3	UTSW	9	16,288,281 (GRCm39)	missense	probably benign	0.00
R1794:Fat3	UTSW	9	15,908,434 (GRCm39)	missense	probably benign	0.15
R1794:Fat3	UTSW	9	15,908,432 (GRCm39)	nonsense	probably null
R1830:Fat3	UTSW	9	15,826,636 (GRCm39)	missense	probably benign	0.03
R1835:Fat3	UTSW	9	15,909,384 (GRCm39)	missense	probably damaging	1.00
R1887:Fat3	UTSW	9	15,878,357 (GRCm39)	missense	probably damaging	1.00
R1898:Fat3	UTSW	9	15,871,426 (GRCm39)	missense	probably damaging	1.00
R1909:Fat3	UTSW	9	15,909,411 (GRCm39)	missense	probably benign
R1912:Fat3	UTSW	9	15,881,284 (GRCm39)	missense	probably damaging	1.00
R1917:Fat3	UTSW	9	15,908,353 (GRCm39)	missense	possibly damaging	0.55
R1967:Fat3	UTSW	9	15,879,591 (GRCm39)	missense	probably benign	0.00
R2070:Fat3	UTSW	9	15,910,666 (GRCm39)	missense	probably benign	0.21
R2100:Fat3	UTSW	9	16,288,726 (GRCm39)	missense	possibly damaging	0.73
R2104:Fat3	UTSW	9	15,909,813 (GRCm39)	missense	possibly damaging	0.77
R2113:Fat3	UTSW	9	15,911,082 (GRCm39)	missense	probably damaging	1.00
R2132:Fat3	UTSW	9	16,158,015 (GRCm39)	critical splice donor site	probably null
R2136:Fat3	UTSW	9	16,288,347 (GRCm39)	missense	probably benign	0.01
R2146:Fat3	UTSW	9	15,901,808 (GRCm39)	missense	probably benign	0.01
R2233:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2234:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2273:Fat3	UTSW	9	15,826,558 (GRCm39)	missense	probably benign
R2285:Fat3	UTSW	9	16,287,469 (GRCm39)	missense	probably damaging	1.00
R2363:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2365:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2367:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2403:Fat3	UTSW	9	15,881,167 (GRCm39)	missense	probably damaging	1.00
R2447:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R2496:Fat3	UTSW	9	15,877,399 (GRCm39)	missense	probably benign	0.01
R2509:Fat3	UTSW	9	15,836,310 (GRCm39)	missense	possibly damaging	0.82
R2932:Fat3	UTSW	9	16,287,240 (GRCm39)	missense	probably damaging	1.00
R2986:Fat3	UTSW	9	15,903,424 (GRCm39)	missense	probably damaging	1.00
R3054:Fat3	UTSW	9	15,871,792 (GRCm39)	missense	probably benign
R3056:Fat3	UTSW	9	15,871,792 (GRCm39)	missense	probably benign
R3729:Fat3	UTSW	9	16,158,337 (GRCm39)	splice site	probably benign
R3745:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3806:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3859:Fat3	UTSW	9	15,908,524 (GRCm39)	nonsense	probably null
R3862:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3890:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3892:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3950:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R3972:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4004:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4005:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4086:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4111:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4113:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4227:Fat3	UTSW	9	16,288,989 (GRCm39)	missense	probably damaging	1.00
R4352:Fat3	UTSW	9	16,158,074 (GRCm39)	missense	possibly damaging	0.55
R4394:Fat3	UTSW	9	15,834,088 (GRCm39)	missense	probably benign	0.11
R4403:Fat3	UTSW	9	15,856,169 (GRCm39)	missense	probably damaging	1.00
R4433:Fat3	UTSW	9	15,942,448 (GRCm39)	missense	probably damaging	0.99
R4453:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4479:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4480:Fat3	UTSW	9	15,909,567 (GRCm39)	missense	probably damaging	1.00
R4521:Fat3	UTSW	9	15,834,238 (GRCm39)	missense	probably null	0.71
R4620:Fat3	UTSW	9	15,908,190 (GRCm39)	missense	probably damaging	1.00
R4700:Fat3	UTSW	9	15,942,469 (GRCm39)	missense	probably damaging	1.00
R4721:Fat3	UTSW	9	15,941,262 (GRCm39)	missense	probably damaging	1.00
R4790:Fat3	UTSW	9	15,909,780 (GRCm39)	missense	probably damaging	1.00
R4796:Fat3	UTSW	9	15,911,028 (GRCm39)	missense	probably benign	0.17
R4823:Fat3	UTSW	9	15,907,803 (GRCm39)	missense	probably benign
R4836:Fat3	UTSW	9	16,289,019 (GRCm39)	missense	probably damaging	1.00
R4842:Fat3	UTSW	9	15,908,883 (GRCm39)	missense	probably damaging	1.00
R4849:Fat3	UTSW	9	16,289,244 (GRCm39)	missense	probably benign	0.03
R4869:Fat3	UTSW	9	16,288,773 (GRCm39)	missense	probably damaging	0.98
R4886:Fat3	UTSW	9	15,932,626 (GRCm39)	missense	probably benign
R4899:Fat3	UTSW	9	15,881,095 (GRCm39)	missense	probably damaging	1.00
R4941:Fat3	UTSW	9	16,286,448 (GRCm39)	missense	probably damaging	1.00
R4986:Fat3	UTSW	9	15,909,636 (GRCm39)	missense	probably damaging	1.00
R5058:Fat3	UTSW	9	15,908,154 (GRCm39)	missense	probably damaging	1.00
R5079:Fat3	UTSW	9	15,910,423 (GRCm39)	missense	probably benign	0.01
R5080:Fat3	UTSW	9	15,910,634 (GRCm39)	missense	probably benign	0.35
R5174:Fat3	UTSW	9	15,910,866 (GRCm39)	missense	probably damaging	1.00
R5183:Fat3	UTSW	9	15,871,609 (GRCm39)	missense	probably damaging	0.99
R5203:Fat3	UTSW	9	16,289,438 (GRCm39)	missense	possibly damaging	0.79
R5216:Fat3	UTSW	9	16,288,833 (GRCm39)	missense	probably damaging	1.00
R5230:Fat3	UTSW	9	15,901,856 (GRCm39)	missense	possibly damaging	0.51
R5318:Fat3	UTSW	9	16,287,925 (GRCm39)	missense	probably damaging	1.00
R5377:Fat3	UTSW	9	16,287,739 (GRCm39)	missense	probably benign	0.05
R5385:Fat3	UTSW	9	15,833,971 (GRCm39)	missense	possibly damaging	0.82
R5436:Fat3	UTSW	9	15,871,810 (GRCm39)	missense	probably benign	0.02
R5437:Fat3	UTSW	9	15,996,604 (GRCm39)	missense	probably damaging	1.00
R5453:Fat3	UTSW	9	15,908,160 (GRCm39)	missense	probably damaging	1.00
R5460:Fat3	UTSW	9	15,830,463 (GRCm39)	missense	probably damaging	1.00
R5516:Fat3	UTSW	9	15,910,005 (GRCm39)	missense	probably damaging	1.00
R5568:Fat3	UTSW	9	16,288,219 (GRCm39)	nonsense	probably null
R5628:Fat3	UTSW	9	15,877,392 (GRCm39)	missense	probably damaging	1.00
R5835:Fat3	UTSW	9	16,287,129 (GRCm39)	missense	probably damaging	1.00
R5845:Fat3	UTSW	9	16,288,506 (GRCm39)	missense	probably damaging	1.00
R5898:Fat3	UTSW	9	15,849,757 (GRCm39)	missense	probably benign	0.15
R5941:Fat3	UTSW	9	15,910,797 (GRCm39)	missense	probably benign	0.07
R5974:Fat3	UTSW	9	15,917,824 (GRCm39)	critical splice donor site	probably null
R5986:Fat3	UTSW	9	15,909,613 (GRCm39)	missense	probably benign	0.22
R6015:Fat3	UTSW	9	16,287,346 (GRCm39)	missense	possibly damaging	0.55
R6031:Fat3	UTSW	9	15,899,788 (GRCm39)	missense	probably benign	0.02
R6031:Fat3	UTSW	9	15,899,788 (GRCm39)	missense	probably benign	0.02
R6042:Fat3	UTSW	9	16,289,113 (GRCm39)	missense	probably benign	0.12
R6051:Fat3	UTSW	9	16,286,751 (GRCm39)	missense	possibly damaging	0.83
R6052:Fat3	UTSW	9	15,833,975 (GRCm39)	missense	probably null
R6119:Fat3	UTSW	9	16,287,864 (GRCm39)	missense	possibly damaging	0.82
R6161:Fat3	UTSW	9	16,288,818 (GRCm39)	missense	probably damaging	1.00
R6254:Fat3	UTSW	9	15,907,441 (GRCm39)	missense	probably benign	0.19
R6318:Fat3	UTSW	9	15,828,280 (GRCm39)	intron	probably benign
R6347:Fat3	UTSW	9	15,909,668 (GRCm39)	missense	probably damaging	1.00
R6348:Fat3	UTSW	9	15,849,287 (GRCm39)	critical splice donor site	probably null
R6351:Fat3	UTSW	9	15,849,694 (GRCm39)	missense	probably damaging	1.00
R6450:Fat3	UTSW	9	15,910,466 (GRCm39)	missense	possibly damaging	0.51
R6460:Fat3	UTSW	9	15,878,296 (GRCm39)	missense	probably damaging	1.00
R6524:Fat3	UTSW	9	15,903,552 (GRCm39)	missense	probably damaging	1.00
R6533:Fat3	UTSW	9	15,910,195 (GRCm39)	missense	probably benign	0.02
R6565:Fat3	UTSW	9	15,826,623 (GRCm39)	missense	probably benign
R6576:Fat3	UTSW	9	16,288,506 (GRCm39)	missense	probably damaging	1.00
R6649:Fat3	UTSW	9	16,288,038 (GRCm39)	missense	probably damaging	1.00
R6716:Fat3	UTSW	9	15,830,565 (GRCm39)	missense	probably benign
R6719:Fat3	UTSW	9	15,907,440 (GRCm39)	missense	probably benign
R6753:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6754:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6755:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6792:Fat3	UTSW	9	16,286,940 (GRCm39)	missense	probably damaging	1.00
R6802:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6803:Fat3	UTSW	9	15,908,083 (GRCm39)	missense	probably damaging	0.99
R6831:Fat3	UTSW	9	16,287,847 (GRCm39)	missense	probably damaging	0.98
R6831:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6833:Fat3	UTSW	9	15,826,357 (GRCm39)	missense	possibly damaging	0.82
R6877:Fat3	UTSW	9	15,910,564 (GRCm39)	missense	probably benign
R6894:Fat3	UTSW	9	15,909,072 (GRCm39)	missense	probably damaging	1.00
R6915:Fat3	UTSW	9	16,289,044 (GRCm39)	missense	probably benign	0.37
R6931:Fat3	UTSW	9	15,871,238 (GRCm39)	missense	possibly damaging	0.89
R6934:Fat3	UTSW	9	16,288,252 (GRCm39)	missense	probably damaging	0.98
R6940:Fat3	UTSW	9	15,828,096 (GRCm39)	splice site	probably null
R6959:Fat3	UTSW	9	15,908,181 (GRCm39)	missense	possibly damaging	0.91
R6969:Fat3	UTSW	9	15,941,212 (GRCm39)	missense	probably benign	0.29
R6986:Fat3	UTSW	9	15,932,631 (GRCm39)	missense	probably damaging	1.00
R6993:Fat3	UTSW	9	15,830,517 (GRCm39)	missense	probably damaging	1.00
R7039:Fat3	UTSW	9	16,287,561 (GRCm39)	missense	probably damaging	1.00
R7051:Fat3	UTSW	9	16,289,123 (GRCm39)	missense	probably damaging	1.00
R7089:Fat3	UTSW	9	15,908,214 (GRCm39)	missense	probably benign	0.01
R7136:Fat3	UTSW	9	16,289,481 (GRCm39)	missense	probably benign
R7137:Fat3	UTSW	9	15,908,444 (GRCm39)	missense	probably damaging	1.00
R7154:Fat3	UTSW	9	15,908,160 (GRCm39)	missense	probably damaging	1.00
R7170:Fat3	UTSW	9	15,917,870 (GRCm39)	missense	probably damaging	0.99
R7183:Fat3	UTSW	9	15,834,133 (GRCm39)	missense	possibly damaging	0.81
R7237:Fat3	UTSW	9	16,288,510 (GRCm39)	missense	probably damaging	1.00
R7288:Fat3	UTSW	9	15,909,888 (GRCm39)	missense	probably damaging	1.00
R7293:Fat3	UTSW	9	15,826,592 (GRCm39)	missense
R7293:Fat3	UTSW	9	15,826,336 (GRCm39)	missense
R7381:Fat3	UTSW	9	16,158,283 (GRCm39)	missense	probably damaging	1.00
R7438:Fat3	UTSW	9	15,899,778 (GRCm39)	missense	probably benign
R7537:Fat3	UTSW	9	15,849,615 (GRCm39)	missense	probably damaging	1.00
R7560:Fat3	UTSW	9	15,908,138 (GRCm39)	missense	probably damaging	1.00
R7585:Fat3	UTSW	9	15,909,558 (GRCm39)	missense	probably benign	0.03
R7623:Fat3	UTSW	9	15,899,620 (GRCm39)	missense	probably damaging	1.00
R7624:Fat3	UTSW	9	15,871,165 (GRCm39)	missense	possibly damaging	0.72
R7684:Fat3	UTSW	9	15,899,564 (GRCm39)	critical splice donor site	probably null
R7690:Fat3	UTSW	9	15,909,477 (GRCm39)	missense	probably damaging	1.00
R7804:Fat3	UTSW	9	15,901,888 (GRCm39)	missense	probably benign	0.01
R7809:Fat3	UTSW	9	15,917,924 (GRCm39)	missense	probably damaging	1.00
R7924:Fat3	UTSW	9	15,910,593 (GRCm39)	missense	probably damaging	1.00
R7925:Fat3	UTSW	9	15,942,656 (GRCm39)	missense	possibly damaging	0.77
R7954:Fat3	UTSW	9	15,909,708 (GRCm39)	missense	probably damaging	1.00
R8021:Fat3	UTSW	9	15,910,405 (GRCm39)	missense	probably damaging	0.99
R8118:Fat3	UTSW	9	15,871,400 (GRCm39)	missense	probably benign
R8141:Fat3	UTSW	9	15,908,362 (GRCm39)	missense	possibly damaging	0.79
R8163:Fat3	UTSW	9	15,871,055 (GRCm39)	missense	probably damaging	1.00
R8170:Fat3	UTSW	9	15,858,792 (GRCm39)	missense	probably damaging	0.97
R8201:Fat3	UTSW	9	15,908,773 (GRCm39)	missense	possibly damaging	0.93
R8258:Fat3	UTSW	9	15,901,887 (GRCm39)	missense	possibly damaging	0.79
R8259:Fat3	UTSW	9	15,901,887 (GRCm39)	missense	possibly damaging	0.79
R8274:Fat3	UTSW	9	16,288,786 (GRCm39)	nonsense	probably null
R8275:Fat3	UTSW	9	16,158,046 (GRCm39)	missense	probably damaging	1.00
R8345:Fat3	UTSW	9	15,910,570 (GRCm39)	missense	probably benign	0.08
R8350:Fat3	UTSW	9	15,826,435 (GRCm39)	missense
R8405:Fat3	UTSW	9	15,907,167 (GRCm39)	missense	probably damaging	1.00
R8421:Fat3	UTSW	9	15,909,480 (GRCm39)	missense	probably damaging	1.00
R8450:Fat3	UTSW	9	15,826,435 (GRCm39)	missense
R8472:Fat3	UTSW	9	16,286,563 (GRCm39)	missense	possibly damaging	0.90
R8482:Fat3	UTSW	9	16,158,263 (GRCm39)	missense	probably benign	0.02
R8680:Fat3	UTSW	9	15,908,703 (GRCm39)	missense	probably damaging	0.99
R8690:Fat3	UTSW	9	15,878,397 (GRCm39)	missense	probably benign	0.45
R8748:Fat3	UTSW	9	15,834,161 (GRCm39)	missense	possibly damaging	0.70
R8756:Fat3	UTSW	9	16,287,885 (GRCm39)	missense	probably damaging	1.00
R8834:Fat3	UTSW	9	15,942,493 (GRCm39)	missense	probably damaging	1.00
R8848:Fat3	UTSW	9	15,878,398 (GRCm39)	missense	probably damaging	1.00
R8884:Fat3	UTSW	9	15,941,280 (GRCm39)	missense	probably damaging	1.00
R8898:Fat3	UTSW	9	15,858,822 (GRCm39)	missense	probably benign	0.04
R8930:Fat3	UTSW	9	15,910,819 (GRCm39)	missense	probably benign	0.06
R8932:Fat3	UTSW	9	15,910,819 (GRCm39)	missense	probably benign	0.06
R8954:Fat3	UTSW	9	16,287,864 (GRCm39)	missense	probably benign	0.00
R8995:Fat3	UTSW	9	16,286,898 (GRCm39)	missense	probably damaging	1.00
R9000:Fat3	UTSW	9	15,918,095 (GRCm39)	missense	probably benign	0.12
R9000:Fat3	UTSW	9	15,871,816 (GRCm39)	missense	possibly damaging	0.82
R9060:Fat3	UTSW	9	15,910,782 (GRCm39)	missense	possibly damaging	0.80
R9116:Fat3	UTSW	9	15,909,421 (GRCm39)	missense	probably benign	0.34
R9136:Fat3	UTSW	9	15,833,738 (GRCm39)	missense
R9193:Fat3	UTSW	9	15,910,248 (GRCm39)	missense	probably benign
R9235:Fat3	UTSW	9	15,833,674 (GRCm39)	missense	probably null
R9257:Fat3	UTSW	9	15,907,863 (GRCm39)	missense	probably benign
R9297:Fat3	UTSW	9	15,908,996 (GRCm39)	missense	probably damaging	1.00
R9307:Fat3	UTSW	9	15,932,719 (GRCm39)	missense	probably damaging	1.00
R9412:Fat3	UTSW	9	15,908,703 (GRCm39)	missense	probably damaging	0.99
R9427:Fat3	UTSW	9	16,288,691 (GRCm39)	nonsense	probably null
R9430:Fat3	UTSW	9	16,287,381 (GRCm39)	missense	probably damaging	1.00
R9480:Fat3	UTSW	9	15,942,703 (GRCm39)	missense	probably damaging	1.00
R9497:Fat3	UTSW	9	15,903,504 (GRCm39)	missense	probably damaging	0.99
R9547:Fat3	UTSW	9	15,911,142 (GRCm39)	missense	possibly damaging	0.86
R9569:Fat3	UTSW	9	15,830,495 (GRCm39)	missense
R9591:Fat3	UTSW	9	16,288,336 (GRCm39)	missense	probably benign	0.01
R9615:Fat3	UTSW	9	16,289,343 (GRCm39)	missense	probably benign	0.00
R9649:Fat3	UTSW	9	15,908,054 (GRCm39)	missense	possibly damaging	0.57
R9671:Fat3	UTSW	9	16,286,871 (GRCm39)	missense	possibly damaging	0.93
R9750:Fat3	UTSW	9	15,915,157 (GRCm39)	missense	probably benign	0.00
R9777:Fat3	UTSW	9	15,826,537 (GRCm39)	missense	probably benign
RF006:Fat3	UTSW	9	15,909,913 (GRCm39)	missense	probably benign	0.36
X0021:Fat3	UTSW	9	15,941,227 (GRCm39)	missense	probably null	0.66
X0026:Fat3	UTSW	9	15,907,629 (GRCm39)	missense	probably benign
X0064:Fat3	UTSW	9	15,830,573 (GRCm39)	missense	probably benign
Z1176:Fat3	UTSW	9	16,286,913 (GRCm39)	missense	probably benign
Z1176:Fat3	UTSW	9	16,286,725 (GRCm39)	missense	probably damaging	1.00
Z1176:Fat3	UTSW	9	15,858,822 (GRCm39)	missense	probably damaging	0.98
Z1177:Fat3	UTSW	9	15,877,287 (GRCm39)	missense	possibly damaging	0.68
Z1177:Fat3	UTSW	9	15,858,834 (GRCm39)	missense	probably damaging	1.00
Z1177:Fat3	UTSW	9	15,834,322 (GRCm39)	missense	possibly damaging	0.81
Z1177:Fat3	UTSW	9	15,881,131 (GRCm39)	missense	probably damaging	0.99

Predicted Primers

PCR Primer
(F):5'- AGCCAAATTCTGCACCACTTATAG -3'
(R):5'- ACCCTGTAAAGACATATGCGTC -3'

Sequencing Primer
(F):5'- GCACCACTTATAGAACCCTTTG -3'
(R):5'- CTGTAAAGACATATGCGTCCATTAAC -3'

Posted On

2016-03-01