Incidental Mutation 'R4857:Ptprf'
| ID |
374034 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ptprf
|
| Ensembl Gene |
ENSMUSG00000033295 |
| Gene Name |
protein tyrosine phosphatase receptor type F |
| Synonyms |
RPTP-LAR, LAR |
| MMRRC Submission |
042468-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.698)
|
| Stock # |
R4857 (G1)
|
| Quality Score |
157 |
|
Status
|
Validated
|
| Chromosome |
4 |
| Chromosomal Location |
118065410-118148602 bp(-) (GRCm39) |
| Type of Mutation |
splice site |
| DNA Base Change (assembly) |
A to G
at 118074394 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000049074]
|
| AlphaFold |
A2A8L5 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000049074
|
| SMART Domains |
Protein: ENSMUSP00000039368
Gene: ENSMUSG00000033295
| Domain | Start | End | E-Value | Type |
|---|
|
IGc2
|
45 |
114 |
2.64e-12 |
SMART |
|
IGc2
|
147 |
214 |
1.48e-15 |
SMART |
|
IG
|
238 |
316 |
1.06e-11 |
SMART |
|
FN3
|
319 |
398 |
6.9e-14 |
SMART |
|
FN3
|
414 |
497 |
5.73e-11 |
SMART |
|
FN3
|
512 |
591 |
4.06e-11 |
SMART |
|
FN3
|
606 |
693 |
8.69e-11 |
SMART |
|
FN3
|
709 |
797 |
8.83e-12 |
SMART |
|
FN3
|
812 |
892 |
3.2e-9 |
SMART |
|
FN3
|
907 |
988 |
2.53e-12 |
SMART |
|
FN3
|
1003 |
1079 |
3.48e-1 |
SMART |
|
coiled coil region
|
1146 |
1175 |
N/A |
INTRINSIC |
|
transmembrane domain
|
1253 |
1275 |
N/A |
INTRINSIC |
|
PTPc
|
1342 |
1600 |
1.12e-138 |
SMART |
|
PTPc
|
1629 |
1891 |
3.4e-129 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000123484
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000124758
|
| SMART Domains |
Protein: ENSMUSP00000119954
Gene: ENSMUSG00000033295
| Domain | Start | End | E-Value | Type |
|---|
|
FN3
|
37 |
116 |
4.06e-11 |
SMART |
|
FN3
|
132 |
220 |
8.83e-12 |
SMART |
|
FN3
|
235 |
315 |
3.2e-9 |
SMART |
|
FN3
|
330 |
411 |
2.53e-12 |
SMART |
|
FN3
|
426 |
502 |
3.48e-1 |
SMART |
|
coiled coil region
|
568 |
597 |
N/A |
INTRINSIC |
|
transmembrane domain
|
676 |
698 |
N/A |
INTRINSIC |
|
PTPc
|
776 |
1034 |
1.12e-138 |
SMART |
|
PTPc
|
1063 |
1325 |
3.4e-129 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000150096
|
| SMART Domains |
Protein: ENSMUSP00000117313
Gene: ENSMUSG00000033295
| Domain | Start | End | E-Value | Type |
|---|
|
FN3
|
14 |
66 |
2.7e1 |
SMART |
|
FN3
|
82 |
165 |
5.73e-11 |
SMART |
|
FN3
|
180 |
259 |
4.06e-11 |
SMART |
|
FN3
|
275 |
372 |
6.69e-12 |
SMART |
|
FN3
|
385 |
461 |
2.83e-1 |
SMART |
|
coiled coil region
|
527 |
556 |
N/A |
INTRINSIC |
|
transmembrane domain
|
635 |
657 |
N/A |
INTRINSIC |
|
PTPc
|
735 |
993 |
1.12e-138 |
SMART |
|
PTPc
|
1022 |
1284 |
3.4e-129 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.3%
- 20x: 92.3%
|
| Validation Efficiency |
97% (115/119) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is a member of the protein tyrosine phosphatase (PTP) family. PTPs are known to be signaling molecules that regulate a variety of cellular processes including cell growth, differentiation, mitotic cycle, and oncogenic transformation. This PTP possesses an extracellular region, a single transmembrane region, and two tandem intracytoplasmic catalytic domains, and thus represents a receptor-type PTP. The extracellular region contains three Ig-like domains, and nine non-Ig like domains similar to that of neural-cell adhesion molecule. This PTP was shown to function in the regulation of epithelial cell-cell contacts at adherents junctions, as well as in the control of beta-catenin signaling. An increased expression level of this protein was found in the insulin-responsive tissue of obese, insulin-resistant individuals, and may contribute to the pathogenesis of insulin resistance. Two alternatively spliced transcript variants of this gene, which encode distinct proteins, have been reported. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygous null females have premature involution of the mammary glands leading to an inability to feed pups. Other characteristics of null mice include defective nerve regeneration and hyperactivity. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 101 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930548G14Rik |
C |
T |
15: 46,488,927 (GRCm39) |
|
noncoding transcript |
Het |
| Aasdh |
A |
T |
5: 77,035,131 (GRCm39) |
F428L |
probably benign |
Het |
| Abca13 |
A |
G |
11: 9,244,143 (GRCm39) |
N2002S |
probably benign |
Het |
| Acot7 |
T |
G |
4: 152,322,211 (GRCm39) |
F248V |
possibly damaging |
Het |
| Acsf2 |
A |
G |
11: 94,460,164 (GRCm39) |
I396T |
probably benign |
Het |
| Agbl1 |
A |
G |
7: 76,069,583 (GRCm39) |
N372D |
probably benign |
Het |
| Ahctf1 |
A |
T |
1: 179,626,922 (GRCm39) |
|
probably benign |
Het |
| Akap11 |
T |
C |
14: 78,736,300 (GRCm39) |
D1830G |
|
Het |
| Bcl7b |
A |
G |
5: 135,202,033 (GRCm39) |
*59W |
probably null |
Het |
| Bdh1 |
A |
G |
16: 31,266,366 (GRCm39) |
|
probably null |
Het |
| Bin3 |
A |
G |
14: 70,366,344 (GRCm39) |
N69S |
probably benign |
Het |
| Bltp3b |
A |
T |
10: 89,615,825 (GRCm39) |
N156I |
probably damaging |
Het |
| Bsdc1 |
T |
C |
4: 129,365,685 (GRCm39) |
|
probably benign |
Het |
| Cacna1i |
T |
C |
15: 80,253,863 (GRCm39) |
V700A |
probably damaging |
Het |
| Calcr |
T |
C |
6: 3,708,511 (GRCm39) |
N225S |
probably benign |
Het |
| Cby2 |
C |
T |
14: 75,830,478 (GRCm39) |
E8K |
probably damaging |
Het |
| Cdh23 |
A |
G |
10: 60,227,563 (GRCm39) |
S1173P |
probably damaging |
Het |
| Cftr |
C |
T |
6: 18,320,974 (GRCm39) |
T1428M |
possibly damaging |
Het |
| Chd1l |
T |
C |
3: 97,479,975 (GRCm39) |
K591E |
probably benign |
Het |
| Chrd |
C |
T |
16: 20,557,508 (GRCm39) |
P709L |
possibly damaging |
Het |
| Ckap4 |
T |
C |
10: 84,369,352 (GRCm39) |
R127G |
possibly damaging |
Het |
| Cnbd2 |
T |
C |
2: 156,209,485 (GRCm39) |
F476S |
probably benign |
Het |
| Dclk3 |
T |
C |
9: 111,297,716 (GRCm39) |
V420A |
probably benign |
Het |
| Dnah5 |
A |
G |
15: 28,345,953 (GRCm39) |
D2431G |
probably benign |
Het |
| Duox1 |
T |
A |
2: 122,146,212 (GRCm39) |
I10N |
probably benign |
Het |
| Ece2 |
T |
A |
16: 20,436,556 (GRCm39) |
V126D |
probably damaging |
Het |
| Elfn1 |
T |
C |
5: 139,958,840 (GRCm39) |
Y615H |
probably damaging |
Het |
| Epha1 |
T |
C |
6: 42,338,416 (GRCm39) |
D720G |
probably benign |
Het |
| Fras1 |
A |
G |
5: 96,926,018 (GRCm39) |
I3741V |
probably benign |
Het |
| Gm53 |
A |
T |
11: 96,142,562 (GRCm39) |
|
noncoding transcript |
Het |
| Grb10 |
G |
T |
11: 11,901,469 (GRCm39) |
|
probably benign |
Het |
| Grid2ip |
A |
G |
5: 143,368,384 (GRCm39) |
H568R |
probably damaging |
Het |
| Gsap |
A |
T |
5: 21,492,797 (GRCm39) |
|
probably null |
Het |
| Gse1 |
T |
C |
8: 121,299,496 (GRCm39) |
|
probably benign |
Het |
| Gstm1 |
T |
C |
3: 107,923,724 (GRCm39) |
R94G |
possibly damaging |
Het |
| Gtf2ird1 |
A |
G |
5: 134,391,398 (GRCm39) |
F866L |
probably damaging |
Het |
| Haao |
T |
A |
17: 84,146,009 (GRCm39) |
|
probably null |
Het |
| Hcn4 |
A |
T |
9: 58,766,853 (GRCm39) |
I805F |
unknown |
Het |
| Hemk1 |
A |
T |
9: 107,206,647 (GRCm39) |
|
probably benign |
Het |
| Il12rb1 |
A |
T |
8: 71,263,232 (GRCm39) |
Y33F |
possibly damaging |
Het |
| Il19 |
T |
A |
1: 130,863,683 (GRCm39) |
I103F |
probably damaging |
Het |
| Itpr1 |
A |
G |
6: 108,387,828 (GRCm39) |
N1522S |
probably benign |
Het |
| Klhdc8a |
A |
G |
1: 132,230,843 (GRCm39) |
Y236C |
probably damaging |
Het |
| Klhl3 |
C |
T |
13: 58,166,620 (GRCm39) |
G404S |
probably damaging |
Het |
| Large2 |
T |
C |
2: 92,196,979 (GRCm39) |
|
probably benign |
Het |
| Lgi1 |
C |
A |
19: 38,294,698 (GRCm39) |
A490E |
probably damaging |
Het |
| Lmbr1 |
A |
G |
5: 29,528,807 (GRCm39) |
L112P |
probably damaging |
Het |
| Lmo7 |
T |
A |
14: 102,124,784 (GRCm39) |
|
probably null |
Het |
| Lpin1 |
A |
C |
12: 16,613,631 (GRCm39) |
I479S |
possibly damaging |
Het |
| Lrrc40 |
T |
A |
3: 157,771,866 (GRCm39) |
|
probably benign |
Het |
| Lrrc9 |
A |
G |
12: 72,546,466 (GRCm39) |
N1218S |
possibly damaging |
Het |
| Map3k9 |
A |
G |
12: 81,771,401 (GRCm39) |
V729A |
probably benign |
Het |
| Marf1 |
A |
T |
16: 13,946,475 (GRCm39) |
Y1215* |
probably null |
Het |
| Moap1 |
T |
A |
12: 102,708,824 (GRCm39) |
I242L |
probably benign |
Het |
| Mpo |
A |
G |
11: 87,687,107 (GRCm39) |
K218E |
probably benign |
Het |
| Mpz |
C |
T |
1: 170,986,379 (GRCm39) |
R98C |
probably damaging |
Het |
| Neb |
T |
G |
2: 52,091,992 (GRCm39) |
K5024T |
probably damaging |
Het |
| Nlrp4b |
C |
T |
7: 10,449,225 (GRCm39) |
T109I |
probably benign |
Het |
| Noc3l |
T |
A |
19: 38,781,244 (GRCm39) |
|
probably null |
Het |
| Nosip |
G |
A |
7: 44,726,102 (GRCm39) |
V220I |
probably benign |
Het |
| Nyap1 |
A |
C |
5: 137,733,840 (GRCm39) |
S398A |
probably damaging |
Het |
| Or12d17 |
A |
G |
17: 37,777,714 (GRCm39) |
M206V |
possibly damaging |
Het |
| Or4a68 |
T |
G |
2: 89,269,967 (GRCm39) |
I219L |
probably damaging |
Het |
| Or4f54 |
A |
G |
2: 111,123,488 (GRCm39) |
N292D |
possibly damaging |
Het |
| Osbpl7 |
T |
C |
11: 96,947,495 (GRCm39) |
|
probably benign |
Het |
| Pard3 |
A |
T |
8: 128,050,535 (GRCm39) |
Y199F |
probably damaging |
Het |
| Pcdha11 |
G |
A |
18: 37,144,505 (GRCm39) |
V199I |
probably benign |
Het |
| Pcdhga8 |
A |
T |
18: 37,859,967 (GRCm39) |
N341I |
probably damaging |
Het |
| Pcsk4 |
A |
G |
10: 80,160,873 (GRCm39) |
S318P |
probably damaging |
Het |
| Phldb1 |
C |
A |
9: 44,607,389 (GRCm39) |
R1272L |
probably damaging |
Het |
| Phlpp2 |
A |
G |
8: 110,603,642 (GRCm39) |
T103A |
probably damaging |
Het |
| Pibf1 |
T |
A |
14: 99,423,937 (GRCm39) |
Y503* |
probably null |
Het |
| Pkn1 |
A |
T |
8: 84,410,856 (GRCm39) |
|
probably null |
Het |
| Pramel22 |
A |
T |
4: 143,383,158 (GRCm39) |
N20K |
possibly damaging |
Het |
| Rbm19 |
C |
A |
5: 120,270,898 (GRCm39) |
|
probably benign |
Het |
| Rcan1 |
T |
C |
16: 92,262,794 (GRCm39) |
D5G |
possibly damaging |
Het |
| Recql5 |
A |
T |
11: 115,819,038 (GRCm39) |
L176Q |
probably damaging |
Het |
| Rev3l |
T |
A |
10: 39,714,455 (GRCm39) |
L2393Q |
probably damaging |
Het |
| Rp1 |
C |
A |
1: 4,422,539 (GRCm39) |
K180N |
probably damaging |
Het |
| Rp1 |
T |
A |
1: 4,422,540 (GRCm39) |
K180M |
probably damaging |
Het |
| Sdk1 |
T |
C |
5: 142,147,531 (GRCm39) |
V1461A |
probably benign |
Het |
| Sdk2 |
A |
T |
11: 113,712,208 (GRCm39) |
L1653* |
probably null |
Het |
| Shroom3 |
G |
T |
5: 93,090,945 (GRCm39) |
V1151F |
probably damaging |
Het |
| Skint10 |
A |
T |
4: 112,603,830 (GRCm39) |
V119D |
possibly damaging |
Het |
| Sncaip |
T |
C |
18: 53,002,297 (GRCm39) |
S273P |
probably benign |
Het |
| Sp1 |
T |
G |
15: 102,339,409 (GRCm39) |
I449S |
probably damaging |
Het |
| Spata31h1 |
T |
C |
10: 82,119,682 (GRCm39) |
T4443A |
possibly damaging |
Het |
| Spats2 |
T |
C |
15: 99,072,301 (GRCm39) |
L78P |
probably damaging |
Het |
| Stambp |
T |
A |
6: 83,533,348 (GRCm39) |
N305I |
probably benign |
Het |
| Stim2 |
A |
T |
5: 54,275,888 (GRCm39) |
S688C |
probably damaging |
Het |
| Sytl3 |
A |
G |
17: 7,003,980 (GRCm39) |
N355S |
probably damaging |
Het |
| Taf4b |
C |
T |
18: 14,937,635 (GRCm39) |
A236V |
probably null |
Het |
| Tnfaip6 |
A |
G |
2: 51,941,086 (GRCm39) |
|
probably null |
Het |
| Trpc2 |
T |
A |
7: 101,733,176 (GRCm39) |
S416T |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,569,210 (GRCm39) |
T27228A |
probably damaging |
Het |
| Ush2a |
T |
A |
1: 188,269,917 (GRCm39) |
D1721E |
probably benign |
Het |
| Usp47 |
T |
A |
7: 111,681,759 (GRCm39) |
H523Q |
probably damaging |
Het |
| Vmn1r8 |
A |
T |
6: 57,013,338 (GRCm39) |
I130F |
probably benign |
Het |
| Vps13b |
A |
G |
15: 35,456,800 (GRCm39) |
S749G |
probably benign |
Het |
| Xrcc5 |
C |
A |
1: 72,365,424 (GRCm39) |
T283K |
possibly damaging |
Het |
| Ydjc |
A |
G |
16: 16,966,002 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Ptprf |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00090:Ptprf
|
APN |
4 |
118,080,417 (GRCm39) |
splice site |
probably benign |
|
|
IGL01337:Ptprf
|
APN |
4 |
118,093,488 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01482:Ptprf
|
APN |
4 |
118,069,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01743:Ptprf
|
APN |
4 |
118,106,095 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL01987:Ptprf
|
APN |
4 |
118,134,567 (GRCm39) |
missense |
probably benign |
|
|
IGL02189:Ptprf
|
APN |
4 |
118,070,839 (GRCm39) |
splice site |
probably benign |
|
|
IGL03067:Ptprf
|
APN |
4 |
118,067,910 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
PIT4677001:Ptprf
|
UTSW |
4 |
118,070,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0382:Ptprf
|
UTSW |
4 |
118,080,591 (GRCm39) |
splice site |
probably benign |
|
|
R0788:Ptprf
|
UTSW |
4 |
118,083,663 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1164:Ptprf
|
UTSW |
4 |
118,114,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1478:Ptprf
|
UTSW |
4 |
118,069,302 (GRCm39) |
nonsense |
probably null |
|
|
R1483:Ptprf
|
UTSW |
4 |
118,093,161 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R1611:Ptprf
|
UTSW |
4 |
118,093,430 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1721:Ptprf
|
UTSW |
4 |
118,082,096 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R1817:Ptprf
|
UTSW |
4 |
118,080,462 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1818:Ptprf
|
UTSW |
4 |
118,067,068 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1860:Ptprf
|
UTSW |
4 |
118,081,129 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2208:Ptprf
|
UTSW |
4 |
118,126,369 (GRCm39) |
splice site |
probably benign |
|
|
R2406:Ptprf
|
UTSW |
4 |
118,126,501 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R2912:Ptprf
|
UTSW |
4 |
118,106,177 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3111:Ptprf
|
UTSW |
4 |
118,068,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3498:Ptprf
|
UTSW |
4 |
118,082,127 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3499:Ptprf
|
UTSW |
4 |
118,082,127 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3615:Ptprf
|
UTSW |
4 |
118,095,080 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3616:Ptprf
|
UTSW |
4 |
118,095,080 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4038:Ptprf
|
UTSW |
4 |
118,114,805 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4243:Ptprf
|
UTSW |
4 |
118,083,649 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4260:Ptprf
|
UTSW |
4 |
118,083,280 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4693:Ptprf
|
UTSW |
4 |
118,068,219 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4726:Ptprf
|
UTSW |
4 |
118,069,414 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4746:Ptprf
|
UTSW |
4 |
118,082,236 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4802:Ptprf
|
UTSW |
4 |
118,067,526 (GRCm39) |
intron |
probably benign |
|
|
R5071:Ptprf
|
UTSW |
4 |
118,069,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5221:Ptprf
|
UTSW |
4 |
118,082,305 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5327:Ptprf
|
UTSW |
4 |
118,093,586 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5336:Ptprf
|
UTSW |
4 |
118,092,831 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5356:Ptprf
|
UTSW |
4 |
118,083,535 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5373:Ptprf
|
UTSW |
4 |
118,083,238 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R5555:Ptprf
|
UTSW |
4 |
118,082,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5693:Ptprf
|
UTSW |
4 |
118,093,374 (GRCm39) |
nonsense |
probably null |
|
|
R5860:Ptprf
|
UTSW |
4 |
118,068,486 (GRCm39) |
intron |
probably benign |
|
|
R5869:Ptprf
|
UTSW |
4 |
118,067,579 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5890:Ptprf
|
UTSW |
4 |
118,081,932 (GRCm39) |
missense |
probably benign |
|
|
R5932:Ptprf
|
UTSW |
4 |
118,068,964 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6028:Ptprf
|
UTSW |
4 |
118,070,826 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6030:Ptprf
|
UTSW |
4 |
118,068,245 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6030:Ptprf
|
UTSW |
4 |
118,068,245 (GRCm39) |
missense |
probably benign |
0.19 |
|
R6088:Ptprf
|
UTSW |
4 |
118,067,952 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6089:Ptprf
|
UTSW |
4 |
118,068,281 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6108:Ptprf
|
UTSW |
4 |
118,080,453 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6320:Ptprf
|
UTSW |
4 |
118,070,011 (GRCm39) |
missense |
probably benign |
|
|
R6741:Ptprf
|
UTSW |
4 |
118,080,565 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6744:Ptprf
|
UTSW |
4 |
118,093,562 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6750:Ptprf
|
UTSW |
4 |
118,088,928 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6906:Ptprf
|
UTSW |
4 |
118,126,474 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7021:Ptprf
|
UTSW |
4 |
118,081,101 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7153:Ptprf
|
UTSW |
4 |
118,088,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7326:Ptprf
|
UTSW |
4 |
118,088,866 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7337:Ptprf
|
UTSW |
4 |
118,068,322 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7374:Ptprf
|
UTSW |
4 |
118,114,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7375:Ptprf
|
UTSW |
4 |
118,070,011 (GRCm39) |
missense |
probably benign |
|
|
R7399:Ptprf
|
UTSW |
4 |
118,083,720 (GRCm39) |
missense |
probably benign |
0.28 |
|
R7417:Ptprf
|
UTSW |
4 |
118,069,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7448:Ptprf
|
UTSW |
4 |
118,092,864 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7530:Ptprf
|
UTSW |
4 |
118,069,945 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7593:Ptprf
|
UTSW |
4 |
118,069,593 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8172:Ptprf
|
UTSW |
4 |
118,068,275 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8239:Ptprf
|
UTSW |
4 |
118,069,309 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R8257:Ptprf
|
UTSW |
4 |
118,083,476 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8331:Ptprf
|
UTSW |
4 |
118,083,263 (GRCm39) |
missense |
probably benign |
0.27 |
|
R8441:Ptprf
|
UTSW |
4 |
118,075,255 (GRCm39) |
splice site |
probably benign |
|
|
R8681:Ptprf
|
UTSW |
4 |
118,088,844 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8771:Ptprf
|
UTSW |
4 |
118,068,987 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8815:Ptprf
|
UTSW |
4 |
118,095,125 (GRCm39) |
missense |
possibly damaging |
0.52 |
|
R8998:Ptprf
|
UTSW |
4 |
118,083,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8999:Ptprf
|
UTSW |
4 |
118,083,671 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9389:Ptprf
|
UTSW |
4 |
118,093,236 (GRCm39) |
missense |
probably benign |
|
|
R9508:Ptprf
|
UTSW |
4 |
118,126,776 (GRCm39) |
nonsense |
probably null |
|
|
R9581:Ptprf
|
UTSW |
4 |
118,092,257 (GRCm39) |
missense |
probably benign |
0.00 |
|
X0067:Ptprf
|
UTSW |
4 |
118,093,223 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
Z1177:Ptprf
|
UTSW |
4 |
118,126,812 (GRCm39) |
missense |
probably benign |
0.04 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATATCCTCGACCTCAGGTGG -3'
(R):5'- GACATGCTTCTGTGTGCTCAC -3'
Sequencing Primer
(F):5'- ACCTCAGGTGGGACCCAG -3'
(R):5'- GTACACACACCTCCATCTCTGG -3'
|
| Posted On |
2016-03-01 |
Incidental Mutation