Mutagenetix > Incidental Mutation

Incidental Mutation 'R4879:Zfp462'

375113

Institutional Source

Beutler Lab

Gene Symbol

Zfp462

Ensembl Gene

ENSMUSG00000060206

Gene Name

zinc finger protein 462

Synonyms

9430078C22Rik, Zfpip, Gt4-2

MMRRC Submission

042488-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.881) question?

Stock #

R4879 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

54945048-55083563 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 55009444 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Valine to Aspartic acid at position 470 (V470D)

Ref Sequence

ENSEMBL: ENSMUSP00000095677 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000030131] [ENSMUST00000079605] [ENSMUST00000098070] [ENSMUST00000133895]

AlphaFold

B1AWL2

Predicted Effect

probably benign
Transcript: ENSMUST00000030131

SMART Domains

Protein: ENSMUSP00000030131
Gene: ENSMUSG00000060206

Domain	Start	End	E-Value	Type
ZnF_C2H2	35	58	4.81e0	SMART
ZnF_C2H2	106	129	6.67e-2	SMART
ZnF_C2H2	153	176	3.47e0	SMART
ZnF_C2H2	210	233	7.29e0	SMART
ZnF_C2H2	311	334	2.17e-1	SMART
ZnF_C2H2	356	379	6.57e0	SMART
ZnF_C2H2	418	441	5.34e-1	SMART
low complexity region	450	463	N/A	INTRINSIC
ZnF_C2H2	501	524	8.22e-2	SMART
ZnF_C2H2	538	561	5.34e0	SMART
ZnF_C2H2	608	631	6.4e0	SMART
low complexity region	655	676	N/A	INTRINSIC
ZnF_C2H2	687	711	3.05e1	SMART
ZnF_C2H2	733	755	1.08e-1	SMART
low complexity region	757	771	N/A	INTRINSIC
ZnF_C2H2	809	831	1.51e0	SMART
ZnF_C2H2	892	914	3.11e-2	SMART
ZnF_C2H2	926	948	4.11e-2	SMART
ZnF_C2H2	955	978	4.98e-1	SMART
ZnF_C2H2	984	1007	5.5e-3	SMART
ZnF_C2H2	1092	1115	7.05e-1	SMART
ZnF_C2H2	1121	1144	5.48e0	SMART
ZnF_C2H2	1155	1177	6.13e-1	SMART
ZnF_C2H2	1201	1223	1.26e-2	SMART
ZnF_C2H2	1229	1252	2.02e-1	SMART
low complexity region	1273	1296	N/A	INTRINSIC
ZnF_C2H2	1315	1337	2.2e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000079605

SMART Domains

Protein: ENSMUSP00000078555
Gene: ENSMUSG00000060206

Domain	Start	End	E-Value	Type
ZnF_C2H2	35	58	4.81e0	SMART
ZnF_C2H2	106	129	6.67e-2	SMART
ZnF_C2H2	153	176	3.47e0	SMART
ZnF_C2H2	210	233	7.29e0	SMART
ZnF_C2H2	311	334	2.17e-1	SMART
ZnF_C2H2	356	379	6.57e0	SMART
ZnF_C2H2	418	441	5.34e-1	SMART
low complexity region	450	463	N/A	INTRINSIC
ZnF_C2H2	501	524	8.22e-2	SMART
ZnF_C2H2	538	561	5.34e0	SMART
ZnF_C2H2	608	631	6.4e0	SMART
low complexity region	655	676	N/A	INTRINSIC
ZnF_C2H2	687	711	3.05e1	SMART
ZnF_C2H2	733	755	1.08e-1	SMART
low complexity region	757	771	N/A	INTRINSIC
ZnF_C2H2	809	831	1.51e0	SMART
ZnF_C2H2	893	915	3.11e-2	SMART
ZnF_C2H2	927	949	4.11e-2	SMART
ZnF_C2H2	956	979	4.98e-1	SMART
ZnF_C2H2	985	1008	5.5e-3	SMART
ZnF_C2H2	1093	1116	7.05e-1	SMART
ZnF_C2H2	1122	1145	5.48e0	SMART
ZnF_C2H2	1156	1178	6.13e-1	SMART
ZnF_C2H2	1202	1224	1.26e-2	SMART
ZnF_C2H2	1230	1253	2.02e-1	SMART
low complexity region	1274	1297	N/A	INTRINSIC
ZnF_C2H2	1316	1338	2.2e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000098070
AA Change: V470D

PolyPhen 2 Score 0.019 (Sensitivity: 0.95; Specificity: 0.80)

SMART Domains

Protein: ENSMUSP00000095677
Gene: ENSMUSG00000060206
AA Change: V470D

Domain	Start	End	E-Value	Type
ZnF_C2H2	4	27	5.81e-2	SMART
low complexity region	81	94	N/A	INTRINSIC
ZnF_C2H2	108	131	1.79e-2	SMART
ZnF_C2H2	162	185	4.65e-1	SMART
low complexity region	194	215	N/A	INTRINSIC
ZnF_C2H2	243	266	4.98e-1	SMART
low complexity region	332	343	N/A	INTRINSIC
ZnF_C2H2	440	463	1.01e-1	SMART
ZnF_C2H2	471	493	2.86e-1	SMART
low complexity region	503	515	N/A	INTRINSIC
low complexity region	536	592	N/A	INTRINSIC
ZnF_C2H2	593	616	2.53e-2	SMART
low complexity region	707	736	N/A	INTRINSIC
ZnF_C2H2	835	858	5.62e0	SMART
ZnF_C2H2	878	900	2.14e0	SMART
ZnF_C2H2	917	940	6.67e-2	SMART
ZnF_C2H2	1023	1046	5.72e-1	SMART
low complexity region	1092	1100	N/A	INTRINSIC
ZnF_C2H2	1107	1130	4.23e0	SMART
ZnF_C2H2	1183	1206	4.81e0	SMART
ZnF_C2H2	1254	1277	6.67e-2	SMART
ZnF_C2H2	1301	1324	3.47e0	SMART
ZnF_C2H2	1358	1381	7.29e0	SMART
ZnF_C2H2	1459	1482	2.17e-1	SMART
ZnF_C2H2	1504	1527	6.57e0	SMART
ZnF_C2H2	1566	1589	5.34e-1	SMART
low complexity region	1598	1611	N/A	INTRINSIC
ZnF_C2H2	1649	1672	8.22e-2	SMART
ZnF_C2H2	1686	1709	5.34e0	SMART
ZnF_C2H2	1756	1779	6.4e0	SMART
low complexity region	1803	1824	N/A	INTRINSIC
ZnF_C2H2	1835	1859	3.05e1	SMART
ZnF_C2H2	1881	1903	1.08e-1	SMART
low complexity region	1905	1919	N/A	INTRINSIC
ZnF_C2H2	1957	1979	1.51e0	SMART
ZnF_C2H2	2014	2036	4.11e-2	SMART
ZnF_C2H2	2043	2066	4.98e-1	SMART
ZnF_C2H2	2072	2095	5.5e-3	SMART
ZnF_C2H2	2180	2203	7.05e-1	SMART
ZnF_C2H2	2209	2232	5.48e0	SMART
ZnF_C2H2	2243	2265	6.13e-1	SMART
ZnF_C2H2	2289	2311	1.26e-2	SMART
ZnF_C2H2	2317	2340	2.02e-1	SMART
low complexity region	2361	2384	N/A	INTRINSIC
ZnF_C2H2	2403	2425	2.2e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000133895

SMART Domains

Protein: ENSMUSP00000122775
Gene: ENSMUSG00000060206

Domain	Start	End	E-Value	Type
ZnF_C2H2	4	27	5.81e-2	SMART
low complexity region	81	93	N/A	INTRINSIC

Meta Mutation Damage Score

0.1505

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 97.0%
20x: 94.4%

Validation Efficiency

97% (86/89)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene belongs to C2H2-type zinc finger family of proteins. It contains multiple C2H2-type zinc fingers and may be involved in transcriptional regulation. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq, Dec 2016]

Allele List at MGI

Other mutations in this stock

Total: 78 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca6	T	A	11: 110,110,526 (GRCm39)	Y541F	probably damaging	Het
Acot12	T	A	13: 91,911,083 (GRCm39)	V136E	probably benign	Het
Aftph	A	G	11: 20,648,311 (GRCm39)		probably null	Het
Ambra1	C	T	2: 91,603,039 (GRCm39)		probably benign	Het
Anks6	C	T	4: 47,030,795 (GRCm39)	G601S	probably damaging	Het
Ano9	T	C	7: 140,690,415 (GRCm39)	D73G	probably benign	Het
Asap3	G	A	4: 135,969,975 (GRCm39)	D778N	probably benign	Het
Atp8a2	G	T	14: 60,245,918 (GRCm39)	Y591*	probably null	Het
Blk	T	C	14: 63,613,414 (GRCm39)	T365A	probably benign	Het
C4b	G	T	17: 34,962,621 (GRCm39)	S27Y	probably damaging	Het
C6	G	T	15: 4,833,129 (GRCm39)		probably null	Het
Ccdc33	T	A	9: 57,974,839 (GRCm39)	I345F	possibly damaging	Het
Cetn3	T	A	13: 81,940,268 (GRCm39)		probably benign	Het
Cntn3	T	A	6: 102,244,389 (GRCm39)	I387L	possibly damaging	Het
Cog8	A	G	8: 107,782,984 (GRCm39)	C102R	probably damaging	Het
Cspg4b	T	C	13: 113,456,321 (GRCm39)	I789T	probably benign	Het
Cyp2c55	CA	C	19: 39,030,522 (GRCm39)		probably null	Het
Defa40	T	A	8: 21,740,380 (GRCm39)	L62Q	probably damaging	Het
Dmxl1	C	T	18: 50,022,534 (GRCm39)	A1624V	probably damaging	Het
Dnah1	T	G	14: 31,022,705 (GRCm39)	E1144A	possibly damaging	Het
Dnah12	T	A	14: 26,439,201 (GRCm39)		probably null	Het
Dnah2	G	A	11: 69,367,517 (GRCm39)	T1794I	probably damaging	Het
Entrep1	T	C	19: 23,953,019 (GRCm39)		probably null	Het
Erbin	A	T	13: 103,971,282 (GRCm39)	M778K	probably benign	Het
Fbxw10	G	T	11: 62,738,573 (GRCm39)	A156S	probably damaging	Het
Flnc	T	A	6: 29,460,805 (GRCm39)	F2632Y	probably damaging	Het
Frmd4a	A	G	2: 4,534,628 (GRCm39)	K160E	probably damaging	Het
Glipr1l2	A	G	10: 111,943,029 (GRCm39)	K295E	probably benign	Het
Herc1	T	A	9: 66,370,119 (GRCm39)	C465*	probably null	Het
Hoxb4	A	G	11: 96,211,014 (GRCm39)	I205V	probably damaging	Het
Ikbke	GCC	G	1: 131,203,004 (GRCm39)		probably null	Het
Il36a	A	G	2: 24,106,032 (GRCm39)	N29S	probably benign	Het
Ilk	A	G	7: 105,391,011 (GRCm39)	S292G	probably benign	Het
Itgb5	G	C	16: 33,696,348 (GRCm39)	G180R	probably damaging	Het
Josd1-ps	T	C	7: 27,648,768 (GRCm39)		noncoding transcript	Het
Kcnip4	T	C	5: 48,567,207 (GRCm39)	D120G	possibly damaging	Het
Kin	A	G	2: 10,085,455 (GRCm39)	D5G	probably benign	Het
Lrrtm2	C	A	18: 35,346,372 (GRCm39)	G310V	probably damaging	Het
Med1	T	C	11: 98,046,186 (GRCm39)		probably benign	Het
Mepce	C	A	5: 137,783,544 (GRCm39)		probably benign	Het
Nckipsd	T	A	9: 108,691,114 (GRCm39)		probably benign	Het
Notch3	T	A	17: 32,366,937 (GRCm39)	Q866L	probably benign	Het
Or52b4	A	T	7: 102,183,962 (GRCm39)	T3S	probably benign	Het
Or5l14	A	T	2: 87,793,040 (GRCm39)	H65Q	possibly damaging	Het
Or8k20	A	T	2: 86,106,107 (GRCm39)	C241*	probably null	Het
Orai1	T	C	5: 123,149,894 (GRCm39)		probably benign	Het
Pate12	G	A	9: 36,344,089 (GRCm39)	C24Y	probably damaging	Het
Pcdhb8	A	T	18: 37,489,219 (GRCm39)	E299V	probably damaging	Het
Pcnx4	G	A	12: 72,613,959 (GRCm39)	D635N	probably damaging	Het
Pex5	T	C	6: 124,375,322 (GRCm39)	I567V	probably benign	Het
Ppfibp2	T	C	7: 107,328,390 (GRCm39)	S485P	probably benign	Het
Sbno1	T	C	5: 124,542,087 (GRCm39)	Y356C	probably damaging	Het
Sdcbp	T	C	4: 6,381,056 (GRCm39)	I67T	possibly damaging	Het
Slc5a7	A	G	17: 54,583,679 (GRCm39)	I537T	probably benign	Het
Slc66a1	A	T	4: 139,029,095 (GRCm39)		probably null	Het
Smad4	A	G	18: 73,774,974 (GRCm39)	C442R	probably damaging	Het
Smpd5	A	G	15: 76,179,070 (GRCm39)	H146R	possibly damaging	Het
Snai2	A	G	16: 14,524,605 (GRCm39)	Y37C	probably benign	Het
Snapc4	C	T	2: 26,256,004 (GRCm39)	S840N	possibly damaging	Het
Stpg2	T	C	3: 138,921,134 (GRCm39)	I113T	probably benign	Het
Tbc1d32	T	C	10: 55,925,125 (GRCm39)		probably null	Het
Tfg	A	T	16: 56,521,520 (GRCm39)	S39R	probably damaging	Het
Thsd7b	T	A	1: 130,116,236 (GRCm39)	S1330T	possibly damaging	Het
Tnfaip3	T	C	10: 18,881,321 (GRCm39)	T322A	probably benign	Het
Tpra1	A	G	6: 88,888,691 (GRCm39)	Y291C	probably damaging	Het
Trcg1	A	G	9: 57,154,003 (GRCm39)	D658G	probably damaging	Het
Trip4	C	T	9: 65,782,304 (GRCm39)	V143I	probably benign	Het
Trp53bp1	T	C	2: 121,033,084 (GRCm39)	K1691E	probably damaging	Het
Ttc8	T	A	12: 98,908,562 (GRCm39)	M77K	possibly damaging	Het
Tubb2a	A	T	13: 34,258,572 (GRCm39)	M406K	probably benign	Het
Txnrd1	T	A	10: 82,717,751 (GRCm39)		probably null	Het
Ugt2a3	C	A	5: 87,479,144 (GRCm39)	R268L	probably benign	Het
Usp34	T	G	11: 23,323,410 (GRCm39)	M982R	possibly damaging	Het
Vmn2r43	T	A	7: 8,258,102 (GRCm39)	K370N	probably benign	Het
Vopp1	A	T	6: 57,739,355 (GRCm39)		probably benign	Het
Vps11	A	C	9: 44,264,597 (GRCm39)	C660G	probably benign	Het
Wnk1	T	C	6: 119,926,338 (GRCm39)	H1137R	probably damaging	Het
Wtap	A	G	17: 13,188,322 (GRCm39)	Y193H	probably damaging	Het

Other mutations in Zfp462

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00162:Zfp462	APN	4	55,011,483 (GRCm39)	splice site	probably null
IGL00421:Zfp462	APN	4	55,023,576 (GRCm39)	missense	probably benign	0.00
IGL00899:Zfp462	APN	4	55,007,732 (GRCm39)	missense	probably damaging	1.00
IGL01549:Zfp462	APN	4	55,013,181 (GRCm39)	missense	probably damaging	1.00
IGL01627:Zfp462	APN	4	55,008,912 (GRCm39)	missense	possibly damaging	0.93
IGL01715:Zfp462	APN	4	55,008,586 (GRCm39)	missense	probably benign	0.20
IGL01862:Zfp462	APN	4	55,023,441 (GRCm39)	missense	probably damaging	1.00
IGL01878:Zfp462	APN	4	55,010,613 (GRCm39)	missense	probably damaging	1.00
IGL01913:Zfp462	APN	4	55,012,138 (GRCm39)	missense	probably benign	0.04
IGL02029:Zfp462	APN	4	55,079,395 (GRCm39)	splice site	probably benign
IGL02338:Zfp462	APN	4	55,010,292 (GRCm39)	missense	possibly damaging	0.88
IGL02552:Zfp462	APN	4	55,010,613 (GRCm39)	missense	probably damaging	1.00
IGL02623:Zfp462	APN	4	55,012,986 (GRCm39)	missense	probably damaging	1.00
IGL02750:Zfp462	APN	4	55,060,236 (GRCm39)	missense	probably null	1.00
IGL02815:Zfp462	APN	4	55,051,303 (GRCm39)	missense	probably damaging	1.00
IGL03204:Zfp462	APN	4	55,080,785 (GRCm39)	missense	possibly damaging	0.80
FR4304:Zfp462	UTSW	4	55,009,758 (GRCm39)	unclassified	probably benign
FR4304:Zfp462	UTSW	4	55,009,757 (GRCm39)	unclassified	probably benign
FR4737:Zfp462	UTSW	4	55,009,760 (GRCm39)	unclassified	probably benign
FR4737:Zfp462	UTSW	4	55,009,758 (GRCm39)	unclassified	probably benign
FR4976:Zfp462	UTSW	4	55,009,761 (GRCm39)	unclassified	probably benign
FR4976:Zfp462	UTSW	4	55,009,760 (GRCm39)	unclassified	probably benign
P0035:Zfp462	UTSW	4	55,009,086 (GRCm39)	missense	probably benign
R0052:Zfp462	UTSW	4	55,011,762 (GRCm39)	missense	probably benign	0.03
R0143:Zfp462	UTSW	4	55,023,402 (GRCm39)	splice site	probably benign
R0145:Zfp462	UTSW	4	55,010,529 (GRCm39)	missense	probably damaging	1.00
R0315:Zfp462	UTSW	4	55,079,314 (GRCm39)	missense	probably damaging	0.99
R0349:Zfp462	UTSW	4	55,008,768 (GRCm39)	missense	probably benign
R0359:Zfp462	UTSW	4	55,013,689 (GRCm39)	missense	probably damaging	1.00
R0413:Zfp462	UTSW	4	55,010,534 (GRCm39)	missense	probably damaging	0.99
R0554:Zfp462	UTSW	4	55,013,689 (GRCm39)	missense	probably damaging	1.00
R0616:Zfp462	UTSW	4	55,011,951 (GRCm39)	missense	probably damaging	1.00
R0631:Zfp462	UTSW	4	55,007,563 (GRCm39)	start codon destroyed	possibly damaging	0.60
R1086:Zfp462	UTSW	4	55,013,000 (GRCm39)	missense	probably damaging	1.00
R1499:Zfp462	UTSW	4	55,060,046 (GRCm39)	missense	probably damaging	1.00
R1509:Zfp462	UTSW	4	55,007,667 (GRCm39)	missense	probably damaging	1.00
R1526:Zfp462	UTSW	4	55,009,002 (GRCm39)	missense	probably benign
R1541:Zfp462	UTSW	4	55,008,928 (GRCm39)	missense	possibly damaging	0.53
R1691:Zfp462	UTSW	4	55,013,489 (GRCm39)	missense	possibly damaging	0.70
R1843:Zfp462	UTSW	4	55,010,010 (GRCm39)	missense	possibly damaging	0.88
R2086:Zfp462	UTSW	4	55,010,830 (GRCm39)	missense	probably damaging	1.00
R2109:Zfp462	UTSW	4	55,008,496 (GRCm39)	missense	probably benign	0.00
R2148:Zfp462	UTSW	4	55,013,670 (GRCm39)	missense	probably benign	0.01
R2179:Zfp462	UTSW	4	55,009,524 (GRCm39)	missense	possibly damaging	0.73
R2325:Zfp462	UTSW	4	55,013,712 (GRCm39)	missense	probably benign
R2352:Zfp462	UTSW	4	55,008,313 (GRCm39)	missense	probably null
R2566:Zfp462	UTSW	4	55,008,522 (GRCm39)	missense	probably benign	0.00
R3879:Zfp462	UTSW	4	55,060,095 (GRCm39)	missense	probably damaging	1.00
R3969:Zfp462	UTSW	4	55,012,402 (GRCm39)	missense	probably damaging	1.00
R4273:Zfp462	UTSW	4	55,008,411 (GRCm39)	missense	probably benign	0.00
R4413:Zfp462	UTSW	4	55,012,672 (GRCm39)	missense	probably damaging	0.99
R4510:Zfp462	UTSW	4	55,008,934 (GRCm39)	missense	possibly damaging	0.86
R4511:Zfp462	UTSW	4	55,008,934 (GRCm39)	missense	possibly damaging	0.86
R4609:Zfp462	UTSW	4	55,011,889 (GRCm39)	missense	probably damaging	1.00
R4632:Zfp462	UTSW	4	55,012,981 (GRCm39)	missense	probably damaging	1.00
R4649:Zfp462	UTSW	4	55,009,349 (GRCm39)	missense	probably benign
R4682:Zfp462	UTSW	4	55,011,376 (GRCm39)	missense	probably damaging	1.00
R4696:Zfp462	UTSW	4	55,008,612 (GRCm39)	missense	probably benign
R4744:Zfp462	UTSW	4	55,011,598 (GRCm39)	missense	probably damaging	1.00
R4747:Zfp462	UTSW	4	55,013,476 (GRCm39)	missense	probably benign	0.00
R4819:Zfp462	UTSW	4	55,060,044 (GRCm39)	missense	probably damaging	1.00
R4827:Zfp462	UTSW	4	55,012,213 (GRCm39)	missense	probably damaging	1.00
R4854:Zfp462	UTSW	4	55,010,668 (GRCm39)	missense	probably damaging	1.00
R4891:Zfp462	UTSW	4	55,060,055 (GRCm39)	missense	probably damaging	1.00
R4993:Zfp462	UTSW	4	55,051,204 (GRCm39)	missense	possibly damaging	0.62
R5118:Zfp462	UTSW	4	55,010,667 (GRCm39)	missense	probably damaging	1.00
R5171:Zfp462	UTSW	4	55,016,986 (GRCm39)	splice site	probably null
R5173:Zfp462	UTSW	4	55,011,115 (GRCm39)	missense	probably damaging	0.99
R5221:Zfp462	UTSW	4	55,016,887 (GRCm39)	missense	possibly damaging	0.86
R5268:Zfp462	UTSW	4	55,012,299 (GRCm39)	missense	probably benign
R5314:Zfp462	UTSW	4	55,013,178 (GRCm39)	missense	probably damaging	1.00
R5429:Zfp462	UTSW	4	55,060,077 (GRCm39)	missense	probably damaging	1.00
R5518:Zfp462	UTSW	4	55,009,818 (GRCm39)	missense	probably damaging	0.99
R5525:Zfp462	UTSW	4	55,050,281 (GRCm39)	missense	possibly damaging	0.73
R5620:Zfp462	UTSW	4	55,013,464 (GRCm39)	missense	probably benign	0.01
R5775:Zfp462	UTSW	4	55,010,590 (GRCm39)	missense	probably damaging	0.99
R6126:Zfp462	UTSW	4	55,023,573 (GRCm39)	missense	probably benign	0.01
R6280:Zfp462	UTSW	4	55,010,253 (GRCm39)	missense	probably benign	0.00
R6325:Zfp462	UTSW	4	55,080,680 (GRCm39)	missense	probably benign	0.04
R6542:Zfp462	UTSW	4	55,023,433 (GRCm39)	missense	probably damaging	1.00
R6612:Zfp462	UTSW	4	55,012,324 (GRCm39)	splice site	probably null
R6663:Zfp462	UTSW	4	55,008,933 (GRCm39)	missense	possibly damaging	0.53
R6872:Zfp462	UTSW	4	55,012,326 (GRCm39)	missense	probably benign	0.01
R6889:Zfp462	UTSW	4	55,007,671 (GRCm39)	missense	probably damaging	1.00
R6896:Zfp462	UTSW	4	55,009,544 (GRCm39)	missense	possibly damaging	0.72
R6913:Zfp462	UTSW	4	55,007,775 (GRCm39)	missense	probably benign	0.25
R6988:Zfp462	UTSW	4	55,080,716 (GRCm39)	missense	probably benign	0.00
R7131:Zfp462	UTSW	4	55,009,380 (GRCm39)	missense	probably benign
R7151:Zfp462	UTSW	4	55,051,271 (GRCm39)	missense	probably damaging	0.99
R7684:Zfp462	UTSW	4	55,008,908 (GRCm39)	missense	probably benign
R7741:Zfp462	UTSW	4	55,008,637 (GRCm39)	missense	probably benign	0.00
R7750:Zfp462	UTSW	4	55,016,958 (GRCm39)	missense	probably benign	0.06
R7812:Zfp462	UTSW	4	55,008,509 (GRCm39)	missense	probably benign	0.00
R7863:Zfp462	UTSW	4	55,007,747 (GRCm39)	missense	probably benign
R7898:Zfp462	UTSW	4	55,012,995 (GRCm39)	missense	probably damaging	0.98
R7993:Zfp462	UTSW	4	55,011,907 (GRCm39)	missense	probably damaging	1.00
R7995:Zfp462	UTSW	4	55,011,907 (GRCm39)	missense	probably damaging	1.00
R8023:Zfp462	UTSW	4	55,073,106 (GRCm39)	critical splice donor site	probably null
R8394:Zfp462	UTSW	4	55,011,862 (GRCm39)	missense	probably damaging	1.00
R8669:Zfp462	UTSW	4	55,051,313 (GRCm39)	missense	probably damaging	0.99
R8877:Zfp462	UTSW	4	55,011,097 (GRCm39)	missense	probably damaging	0.98
R8980:Zfp462	UTSW	4	55,009,681 (GRCm39)	unclassified	probably benign
R9023:Zfp462	UTSW	4	55,007,563 (GRCm39)	start codon destroyed	probably null	0.00
R9243:Zfp462	UTSW	4	55,009,595 (GRCm39)	nonsense	probably null
R9378:Zfp462	UTSW	4	55,011,510 (GRCm39)	missense	probably benign	0.00
R9417:Zfp462	UTSW	4	55,016,988 (GRCm39)	missense	probably benign	0.26
R9476:Zfp462	UTSW	4	55,080,735 (GRCm39)	missense	probably benign
R9510:Zfp462	UTSW	4	55,080,735 (GRCm39)	missense	probably benign
R9610:Zfp462	UTSW	4	55,009,545 (GRCm39)	missense	possibly damaging	0.73
R9628:Zfp462	UTSW	4	55,009,423 (GRCm39)	missense	probably benign

Predicted Primers

PCR Primer
(F):5'- GCTCTGATGAGGACTTAAATGAGG -3'
(R):5'- CCATTGATGCTGGAGCTCTC -3'

Sequencing Primer
(F):5'- TCAGGACTGTCTGCAGAGC -3'
(R):5'- ATGCTGGAGCTCTCGTAAGATACC -3'

Posted On

2016-03-17