Incidental Mutation 'R0281:Zfp318'
| ID |
37576 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zfp318
|
| Ensembl Gene |
ENSMUSG00000015597 |
| Gene Name |
zinc finger protein 318 |
| Synonyms |
2610034E08Rik, TZF, D530032D06Rik |
| MMRRC Submission |
038503-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0281 (G1)
|
| Quality Score |
202 |
|
Status
|
Validated
|
| Chromosome |
17 |
| Chromosomal Location |
46694657-46731846 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 46723540 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Serine
at position 1848
(P1848S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109109
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000113481]
[ENSMUST00000138127]
[ENSMUST00000152472]
|
| AlphaFold |
Q99PP2 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113481
AA Change: P1848S
PolyPhen 2
Score 0.054 (Sensitivity: 0.94; Specificity: 0.84)
|
| SMART Domains |
Protein: ENSMUSP00000109109
Gene: ENSMUSG00000015597
AA Change: P1848S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
30 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
169 |
N/A |
INTRINSIC |
|
low complexity region
|
208 |
221 |
N/A |
INTRINSIC |
|
low complexity region
|
291 |
304 |
N/A |
INTRINSIC |
|
coiled coil region
|
348 |
376 |
N/A |
INTRINSIC |
|
SCOP:d1eq1a_
|
916 |
995 |
2e-4 |
SMART |
|
low complexity region
|
1018 |
1055 |
N/A |
INTRINSIC |
|
ZnF_U1
|
1085 |
1119 |
5.99e-7 |
SMART |
|
ZnF_C2H2
|
1088 |
1112 |
4.5e1 |
SMART |
|
ZnF_U1
|
1155 |
1189 |
2.1e-11 |
SMART |
|
ZnF_C2H2
|
1158 |
1180 |
4.62e1 |
SMART |
|
low complexity region
|
1225 |
1238 |
N/A |
INTRINSIC |
|
low complexity region
|
1358 |
1371 |
N/A |
INTRINSIC |
|
low complexity region
|
1640 |
1651 |
N/A |
INTRINSIC |
|
Blast:HNHc
|
1660 |
1710 |
3e-17 |
BLAST |
|
low complexity region
|
2001 |
2013 |
N/A |
INTRINSIC |
|
low complexity region
|
2110 |
2121 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000123733
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000136017
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000138127
|
| SMART Domains |
Protein: ENSMUSP00000116544
Gene: ENSMUSG00000015597
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
3 |
15 |
N/A |
INTRINSIC |
|
low complexity region
|
30 |
127 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
169 |
N/A |
INTRINSIC |
|
low complexity region
|
208 |
221 |
N/A |
INTRINSIC |
|
low complexity region
|
291 |
304 |
N/A |
INTRINSIC |
|
coiled coil region
|
348 |
376 |
N/A |
INTRINSIC |
|
Blast:HOLI
|
854 |
1114 |
8e-19 |
BLAST |
|
SCOP:d1eq1a_
|
916 |
995 |
6e-5 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000152472
|
| SMART Domains |
Protein: ENSMUSP00000116132
Gene: ENSMUSG00000015597
| Domain | Start | End | E-Value | Type |
|---|
|
coiled coil region
|
3 |
30 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1016 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 93.9%
|
| Validation Efficiency |
98% (104/106) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for an ENU-induced allele exhibit reduced male fertility and altered IgM and IgD levels. Null mutants displayed normal level of circulating B cells with decreased IgD and increased IgM levels. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 101 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933430I17Rik |
A |
T |
4: 62,464,304 (GRCm39) |
R374* |
probably null |
Het |
| 5930422O12Rik |
A |
T |
8: 33,919,407 (GRCm39) |
R76* |
probably null |
Het |
| A1cf |
G |
A |
19: 31,923,214 (GRCm39) |
A505T |
probably benign |
Het |
| Abcc5 |
T |
A |
16: 20,241,150 (GRCm39) |
I12F |
probably damaging |
Het |
| Abcf2 |
T |
C |
5: 24,771,562 (GRCm39) |
E555G |
probably damaging |
Het |
| Acan |
A |
T |
7: 78,750,033 (GRCm39) |
E1601D |
probably damaging |
Het |
| Acsbg3 |
T |
A |
17: 57,192,169 (GRCm39) |
Y577* |
probably null |
Het |
| Adam2 |
T |
A |
14: 66,275,055 (GRCm39) |
K559N |
probably benign |
Het |
| Akap11 |
A |
C |
14: 78,747,529 (GRCm39) |
D1619E |
possibly damaging |
Het |
| Ankrd11 |
T |
C |
8: 123,622,307 (GRCm39) |
D515G |
probably benign |
Het |
| Ankrd27 |
T |
A |
7: 35,318,796 (GRCm39) |
N562K |
probably damaging |
Het |
| Atp10b |
T |
C |
11: 43,044,131 (GRCm39) |
I119T |
probably benign |
Het |
| Atr |
T |
C |
9: 95,819,619 (GRCm39) |
I2202T |
probably benign |
Het |
| Bltp2 |
C |
T |
11: 78,162,750 (GRCm39) |
L871F |
possibly damaging |
Het |
| Brd4 |
T |
A |
17: 32,432,514 (GRCm39) |
|
probably benign |
Het |
| Catsperg2 |
C |
T |
7: 29,405,996 (GRCm39) |
C634Y |
possibly damaging |
Het |
| Cep192 |
A |
G |
18: 67,961,553 (GRCm39) |
|
probably benign |
Het |
| Cfap65 |
T |
A |
1: 74,966,230 (GRCm39) |
I366F |
probably damaging |
Het |
| Cnga4 |
G |
T |
7: 105,056,875 (GRCm39) |
R326L |
probably damaging |
Het |
| Cntnap5b |
T |
A |
1: 99,999,878 (GRCm39) |
M212K |
probably benign |
Het |
| Col6a6 |
T |
A |
9: 105,661,315 (GRCm39) |
M265L |
probably benign |
Het |
| Cspg4b |
A |
T |
13: 113,505,677 (GRCm39) |
I727F |
probably damaging |
Het |
| Cyp26b1 |
A |
T |
6: 84,551,538 (GRCm39) |
F417Y |
probably damaging |
Het |
| Dhx15 |
A |
T |
5: 52,308,088 (GRCm39) |
M768K |
probably benign |
Het |
| Drc7 |
G |
A |
8: 95,797,881 (GRCm39) |
R433H |
possibly damaging |
Het |
| Duox2 |
C |
T |
2: 122,122,785 (GRCm39) |
V550M |
probably benign |
Het |
| Elmo2 |
A |
G |
2: 165,138,810 (GRCm39) |
L456P |
probably damaging |
Het |
| Fbxo39 |
T |
C |
11: 72,208,356 (GRCm39) |
I236T |
probably benign |
Het |
| Fezf2 |
A |
G |
14: 12,343,977 (GRCm38) |
C305R |
probably damaging |
Het |
| Fndc3b |
C |
A |
3: 27,511,155 (GRCm39) |
C785F |
probably benign |
Het |
| Gm12253 |
T |
C |
11: 58,330,838 (GRCm39) |
|
probably benign |
Het |
| Gnat2 |
T |
A |
3: 108,002,878 (GRCm39) |
Y95* |
probably null |
Het |
| Gopc |
T |
C |
10: 52,226,774 (GRCm39) |
K220E |
probably damaging |
Het |
| Hectd4 |
G |
A |
5: 121,392,314 (GRCm39) |
D193N |
possibly damaging |
Het |
| Hexa |
G |
A |
9: 59,461,509 (GRCm39) |
|
probably null |
Het |
| Hspa4l |
T |
C |
3: 40,739,840 (GRCm39) |
|
probably benign |
Het |
| Hspa5 |
T |
C |
2: 34,664,332 (GRCm39) |
S301P |
probably damaging |
Het |
| Ice1 |
A |
T |
13: 70,752,166 (GRCm39) |
S1307T |
possibly damaging |
Het |
| Igtp |
T |
C |
11: 58,096,880 (GRCm39) |
L17P |
probably damaging |
Het |
| Itk |
T |
C |
11: 46,244,743 (GRCm39) |
Y225C |
probably damaging |
Het |
| Kifc3 |
A |
G |
8: 95,830,088 (GRCm39) |
V560A |
probably damaging |
Het |
| Lama1 |
A |
G |
17: 68,124,564 (GRCm39) |
N2875D |
probably damaging |
Het |
| Lasp1 |
C |
A |
11: 97,697,677 (GRCm39) |
C32* |
probably null |
Het |
| Lcp2 |
T |
A |
11: 34,019,854 (GRCm39) |
|
probably benign |
Het |
| Lhx9 |
C |
T |
1: 138,760,642 (GRCm39) |
G236D |
probably benign |
Het |
| Lrrc38 |
A |
T |
4: 143,076,979 (GRCm39) |
I81F |
probably damaging |
Het |
| Ly6a |
C |
T |
15: 74,867,236 (GRCm39) |
V94M |
probably benign |
Het |
| Map3k13 |
A |
G |
16: 21,732,907 (GRCm39) |
E503G |
probably damaging |
Het |
| Mertk |
T |
C |
2: 128,624,541 (GRCm39) |
|
probably benign |
Het |
| Mrtfb |
T |
A |
16: 13,230,027 (GRCm39) |
I915N |
probably damaging |
Het |
| Msantd2 |
G |
A |
9: 37,434,515 (GRCm39) |
D252N |
possibly damaging |
Het |
| Mtmr12 |
T |
A |
15: 12,257,792 (GRCm39) |
L290* |
probably null |
Het |
| Myo3a |
T |
C |
2: 22,250,409 (GRCm39) |
I92T |
probably benign |
Het |
| Naglu |
T |
A |
11: 100,964,853 (GRCm39) |
N313K |
probably damaging |
Het |
| Nceh1 |
T |
C |
3: 27,276,953 (GRCm39) |
V92A |
possibly damaging |
Het |
| Ncf4 |
A |
G |
15: 78,135,083 (GRCm39) |
T47A |
probably damaging |
Het |
| Nrp1 |
T |
A |
8: 129,187,164 (GRCm39) |
F403L |
probably damaging |
Het |
| Nxph3 |
T |
C |
11: 95,402,082 (GRCm39) |
T111A |
possibly damaging |
Het |
| Obscn |
T |
A |
11: 58,929,441 (GRCm39) |
E6061V |
probably damaging |
Het |
| Obsl1 |
C |
A |
1: 75,469,571 (GRCm39) |
G1149W |
probably damaging |
Het |
| Or14c39 |
A |
G |
7: 86,344,068 (GRCm39) |
T135A |
probably benign |
Het |
| Or2k2 |
A |
T |
4: 58,784,981 (GRCm39) |
V247E |
probably damaging |
Het |
| Or2p2 |
T |
A |
13: 21,256,544 (GRCm39) |
Y309F |
probably benign |
Het |
| Or5b123 |
A |
G |
19: 13,596,849 (GRCm39) |
T65A |
probably benign |
Het |
| Or5d14 |
C |
T |
2: 87,880,756 (GRCm39) |
V71I |
possibly damaging |
Het |
| Or5p68 |
A |
C |
7: 107,946,121 (GRCm39) |
D22E |
probably benign |
Het |
| Or6c70 |
T |
A |
10: 129,710,415 (GRCm39) |
L70F |
possibly damaging |
Het |
| Pde9a |
T |
C |
17: 31,674,080 (GRCm39) |
V55A |
probably damaging |
Het |
| Pip4k2c |
A |
T |
10: 127,041,690 (GRCm39) |
|
probably null |
Het |
| Plvap |
T |
C |
8: 71,964,026 (GRCm39) |
N112S |
probably damaging |
Het |
| Pop1 |
T |
A |
15: 34,530,004 (GRCm39) |
|
probably null |
Het |
| Ppip5k2 |
T |
C |
1: 97,644,278 (GRCm39) |
H1113R |
possibly damaging |
Het |
| Ptprk |
A |
T |
10: 28,449,388 (GRCm39) |
I962F |
probably damaging |
Het |
| Rad51ap2 |
T |
C |
12: 11,507,043 (GRCm39) |
S322P |
possibly damaging |
Het |
| Rasal1 |
A |
G |
5: 120,812,670 (GRCm39) |
T565A |
probably benign |
Het |
| Rbm15 |
C |
A |
3: 107,238,471 (GRCm39) |
R642S |
probably damaging |
Het |
| Rpsa |
G |
A |
9: 119,960,069 (GRCm39) |
E211K |
possibly damaging |
Het |
| Ryr3 |
A |
G |
2: 112,517,155 (GRCm39) |
S3303P |
probably damaging |
Het |
| Scg2 |
T |
A |
1: 79,413,229 (GRCm39) |
N458I |
possibly damaging |
Het |
| Setx |
A |
G |
2: 29,069,655 (GRCm39) |
T2487A |
probably benign |
Het |
| Slc4a5 |
G |
A |
6: 83,244,549 (GRCm39) |
|
probably benign |
Het |
| Slc8a2 |
T |
A |
7: 15,874,914 (GRCm39) |
D387E |
probably benign |
Het |
| Smarcc2 |
A |
G |
10: 128,310,591 (GRCm39) |
T407A |
probably benign |
Het |
| Snap25 |
A |
G |
2: 136,619,384 (GRCm39) |
D179G |
probably damaging |
Het |
| Socs4 |
T |
C |
14: 47,527,325 (GRCm39) |
S74P |
probably benign |
Het |
| Sp6 |
T |
A |
11: 96,912,751 (GRCm39) |
Y155N |
probably benign |
Het |
| Srrt |
C |
T |
5: 137,294,389 (GRCm39) |
|
probably benign |
Het |
| Steap1 |
C |
T |
5: 5,786,431 (GRCm39) |
M335I |
probably benign |
Het |
| Stra6 |
A |
T |
9: 58,052,772 (GRCm39) |
Y250F |
probably benign |
Het |
| Svil |
T |
C |
18: 5,094,582 (GRCm39) |
S1421P |
probably damaging |
Het |
| Tcea3 |
G |
A |
4: 135,998,677 (GRCm39) |
C317Y |
probably damaging |
Het |
| Tmco6 |
T |
C |
18: 36,870,757 (GRCm39) |
L117S |
probably damaging |
Het |
| Trp53bp1 |
T |
C |
2: 121,100,718 (GRCm39) |
K89E |
probably damaging |
Het |
| Trp63 |
T |
A |
16: 25,583,052 (GRCm39) |
|
probably benign |
Het |
| Ube2d2a |
A |
G |
18: 35,933,185 (GRCm39) |
Y74C |
probably damaging |
Het |
| Usp19 |
T |
G |
9: 108,375,708 (GRCm39) |
F885V |
probably damaging |
Het |
| Utp18 |
T |
A |
11: 93,773,003 (GRCm39) |
|
probably benign |
Het |
| Vmn2r116 |
T |
C |
17: 23,620,387 (GRCm39) |
I707T |
possibly damaging |
Het |
| Vmn2r68 |
T |
A |
7: 84,882,457 (GRCm39) |
|
probably benign |
Het |
| Vmn2r68 |
C |
G |
7: 84,882,466 (GRCm39) |
|
probably null |
Het |
| Zfp984 |
G |
T |
4: 147,839,722 (GRCm39) |
N376K |
probably benign |
Het |
|
| Other mutations in Zfp318 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00705:Zfp318
|
APN |
17 |
46,723,398 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00978:Zfp318
|
APN |
17 |
46,724,652 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01016:Zfp318
|
APN |
17 |
46,711,003 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01310:Zfp318
|
APN |
17 |
46,724,153 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01453:Zfp318
|
APN |
17 |
46,719,942 (GRCm39) |
splice site |
probably null |
|
|
IGL01887:Zfp318
|
APN |
17 |
46,710,094 (GRCm39) |
missense |
probably benign |
0.07 |
|
IGL02025:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02026:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02070:Zfp318
|
APN |
17 |
46,707,644 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02182:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02187:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02188:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02189:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02190:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02191:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02192:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02203:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02224:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02230:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02231:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02232:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02233:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02234:Zfp318
|
APN |
17 |
46,707,736 (GRCm39) |
nonsense |
probably null |
|
|
IGL02412:Zfp318
|
APN |
17 |
46,720,043 (GRCm39) |
nonsense |
probably null |
|
|
IGL02792:Zfp318
|
APN |
17 |
46,720,104 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02826:Zfp318
|
APN |
17 |
46,709,680 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Wonton
|
UTSW |
17 |
46,720,618 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
I0000:Zfp318
|
UTSW |
17 |
46,710,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0206:Zfp318
|
UTSW |
17 |
46,709,945 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0240:Zfp318
|
UTSW |
17 |
46,707,739 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0240:Zfp318
|
UTSW |
17 |
46,707,739 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0350:Zfp318
|
UTSW |
17 |
46,724,124 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0383:Zfp318
|
UTSW |
17 |
46,724,222 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0453:Zfp318
|
UTSW |
17 |
46,707,634 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1014:Zfp318
|
UTSW |
17 |
46,723,462 (GRCm39) |
nonsense |
probably null |
|
|
R1166:Zfp318
|
UTSW |
17 |
46,720,618 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1208:Zfp318
|
UTSW |
17 |
46,723,446 (GRCm39) |
unclassified |
probably benign |
|
|
R1208:Zfp318
|
UTSW |
17 |
46,723,446 (GRCm39) |
unclassified |
probably benign |
|
|
R1327:Zfp318
|
UTSW |
17 |
46,724,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1330:Zfp318
|
UTSW |
17 |
46,724,684 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1737:Zfp318
|
UTSW |
17 |
46,710,403 (GRCm39) |
missense |
probably benign |
0.35 |
|
R1800:Zfp318
|
UTSW |
17 |
46,722,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1846:Zfp318
|
UTSW |
17 |
46,724,592 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1848:Zfp318
|
UTSW |
17 |
46,716,981 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1861:Zfp318
|
UTSW |
17 |
46,722,366 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1913:Zfp318
|
UTSW |
17 |
46,723,450 (GRCm39) |
unclassified |
probably benign |
|
|
R1913:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R2059:Zfp318
|
UTSW |
17 |
46,707,950 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2085:Zfp318
|
UTSW |
17 |
46,720,590 (GRCm39) |
splice site |
probably null |
|
|
R2122:Zfp318
|
UTSW |
17 |
46,724,297 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2339:Zfp318
|
UTSW |
17 |
46,710,389 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4526:Zfp318
|
UTSW |
17 |
46,723,284 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4564:Zfp318
|
UTSW |
17 |
46,723,741 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4689:Zfp318
|
UTSW |
17 |
46,710,560 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4795:Zfp318
|
UTSW |
17 |
46,722,988 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5256:Zfp318
|
UTSW |
17 |
46,722,995 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5317:Zfp318
|
UTSW |
17 |
46,723,463 (GRCm39) |
unclassified |
probably benign |
|
|
R5323:Zfp318
|
UTSW |
17 |
46,697,662 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5436:Zfp318
|
UTSW |
17 |
46,723,975 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5485:Zfp318
|
UTSW |
17 |
46,723,180 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R5627:Zfp318
|
UTSW |
17 |
46,724,062 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5643:Zfp318
|
UTSW |
17 |
46,720,170 (GRCm39) |
intron |
probably benign |
|
|
R5782:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R5783:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R5820:Zfp318
|
UTSW |
17 |
46,723,699 (GRCm39) |
missense |
probably benign |
|
|
R5895:Zfp318
|
UTSW |
17 |
46,709,959 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6189:Zfp318
|
UTSW |
17 |
46,723,440 (GRCm39) |
unclassified |
probably benign |
|
|
R6385:Zfp318
|
UTSW |
17 |
46,721,932 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6428:Zfp318
|
UTSW |
17 |
46,710,262 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6471:Zfp318
|
UTSW |
17 |
46,710,431 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6666:Zfp318
|
UTSW |
17 |
46,720,140 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6812:Zfp318
|
UTSW |
17 |
46,723,468 (GRCm39) |
unclassified |
probably benign |
|
|
R6852:Zfp318
|
UTSW |
17 |
46,723,464 (GRCm39) |
unclassified |
probably benign |
|
|
R6852:Zfp318
|
UTSW |
17 |
46,723,459 (GRCm39) |
unclassified |
probably benign |
|
|
R6852:Zfp318
|
UTSW |
17 |
46,723,460 (GRCm39) |
unclassified |
probably benign |
|
|
R6854:Zfp318
|
UTSW |
17 |
46,723,468 (GRCm39) |
unclassified |
probably benign |
|
|
R6980:Zfp318
|
UTSW |
17 |
46,708,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6999:Zfp318
|
UTSW |
17 |
46,710,969 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7164:Zfp318
|
UTSW |
17 |
46,716,865 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7164:Zfp318
|
UTSW |
17 |
46,708,232 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7175:Zfp318
|
UTSW |
17 |
46,697,774 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7233:Zfp318
|
UTSW |
17 |
46,716,978 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7339:Zfp318
|
UTSW |
17 |
46,722,173 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7426:Zfp318
|
UTSW |
17 |
46,710,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7600:Zfp318
|
UTSW |
17 |
46,695,210 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7608:Zfp318
|
UTSW |
17 |
46,710,935 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7779:Zfp318
|
UTSW |
17 |
46,710,820 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8057:Zfp318
|
UTSW |
17 |
46,710,692 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R8273:Zfp318
|
UTSW |
17 |
46,723,301 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8274:Zfp318
|
UTSW |
17 |
46,723,915 (GRCm39) |
missense |
probably benign |
|
|
R8695:Zfp318
|
UTSW |
17 |
46,723,576 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8822:Zfp318
|
UTSW |
17 |
46,723,831 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8851:Zfp318
|
UTSW |
17 |
46,710,761 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8913:Zfp318
|
UTSW |
17 |
46,722,699 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8953:Zfp318
|
UTSW |
17 |
46,731,356 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9031:Zfp318
|
UTSW |
17 |
46,723,433 (GRCm39) |
missense |
probably benign |
0.15 |
|
R9327:Zfp318
|
UTSW |
17 |
46,721,892 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9329:Zfp318
|
UTSW |
17 |
46,722,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9352:Zfp318
|
UTSW |
17 |
46,721,284 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9633:Zfp318
|
UTSW |
17 |
46,710,421 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9662:Zfp318
|
UTSW |
17 |
46,724,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9728:Zfp318
|
UTSW |
17 |
46,707,713 (GRCm39) |
missense |
probably benign |
0.10 |
|
R9755:Zfp318
|
UTSW |
17 |
46,722,055 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0026:Zfp318
|
UTSW |
17 |
46,721,564 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
X0054:Zfp318
|
UTSW |
17 |
46,723,535 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
X0065:Zfp318
|
UTSW |
17 |
46,721,915 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1176:Zfp318
|
UTSW |
17 |
46,716,904 (GRCm39) |
missense |
probably benign |
0.03 |
|
| Predicted Primers |
PCR Primer
(F):5'- GGCCACCTGGTACAGATTCAACTTC -3'
(R):5'- GATTCCTCAGAGATGCAAACCCCTC -3'
Sequencing Primer
(F):5'- CAACGGACCTCAGAAGTTGATAG -3'
(R):5'- CTACCTCTAAGTGTGTAGTGTCAAAG -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation