Incidental Mutation 'R4897:Pcdha7'
| ID |
375847 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Pcdha7
|
| Ensembl Gene |
ENSMUSG00000104318 |
| Gene Name |
protocadherin alpha 7 |
| Synonyms |
Crnr4, Cnr4 |
| MMRRC Submission |
042501-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.099)
|
| Stock # |
R4897 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
18 |
| Chromosomal Location |
37106864-37320716 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 37108646 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 557
(D557G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000142156
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000070797]
[ENSMUST00000115661]
[ENSMUST00000115662]
[ENSMUST00000192168]
[ENSMUST00000192295]
[ENSMUST00000192503]
[ENSMUST00000192512]
[ENSMUST00000192631]
[ENSMUST00000194544]
[ENSMUST00000194751]
[ENSMUST00000193839]
[ENSMUST00000193777]
[ENSMUST00000193389]
[ENSMUST00000195590]
|
| AlphaFold |
Q91Y13 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000070797
|
| SMART Domains |
Protein: ENSMUSP00000068828
Gene: ENSMUSG00000103442
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
22 |
132 |
3.09e-2 |
SMART |
|
CA
|
156 |
241 |
6.14e-20 |
SMART |
|
CA
|
265 |
349 |
3.92e-27 |
SMART |
|
CA
|
373 |
454 |
4.94e-24 |
SMART |
|
CA
|
478 |
564 |
1e-24 |
SMART |
|
CA
|
592 |
672 |
4.55e-14 |
SMART |
|
transmembrane domain
|
694 |
716 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_tail
|
797 |
931 |
5.3e-58 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115661
|
| SMART Domains |
Protein: ENSMUSP00000111325
Gene: ENSMUSG00000103458
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
20 |
131 |
5.3e-2 |
SMART |
|
CA
|
155 |
240 |
1.51e-19 |
SMART |
|
CA
|
264 |
348 |
7.6e-25 |
SMART |
|
CA
|
372 |
453 |
1.42e-24 |
SMART |
|
CA
|
477 |
563 |
1.42e-24 |
SMART |
|
CA
|
594 |
674 |
4.12e-12 |
SMART |
|
low complexity region
|
706 |
721 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_tail
|
796 |
930 |
3.9e-58 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000115662
|
| SMART Domains |
Protein: ENSMUSP00000111326
Gene: ENSMUSG00000104148
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
45 |
131 |
6.34e-2 |
SMART |
|
CA
|
155 |
240 |
2.98e-18 |
SMART |
|
CA
|
264 |
348 |
2.17e-29 |
SMART |
|
CA
|
372 |
453 |
2.84e-24 |
SMART |
|
CA
|
477 |
563 |
5.02e-25 |
SMART |
|
CA
|
594 |
675 |
8.16e-16 |
SMART |
|
transmembrane domain
|
695 |
717 |
N/A |
INTRINSIC |
|
low complexity region
|
916 |
940 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192168
|
| SMART Domains |
Protein: ENSMUSP00000142293
Gene: ENSMUSG00000103092
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
21 |
131 |
2.2e-2 |
SMART |
|
CA
|
155 |
240 |
2.05e-21 |
SMART |
|
CA
|
264 |
348 |
8.81e-21 |
SMART |
|
CA
|
372 |
453 |
2.01e-24 |
SMART |
|
CA
|
477 |
563 |
1.42e-24 |
SMART |
|
CA
|
591 |
673 |
1.63e-15 |
SMART |
|
transmembrane domain
|
693 |
715 |
N/A |
INTRINSIC |
|
low complexity region
|
902 |
926 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192295
|
| SMART Domains |
Protein: ENSMUSP00000142103
Gene: ENSMUSG00000104252
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
20 |
131 |
5.3e-2 |
SMART |
|
CA
|
155 |
240 |
1.51e-19 |
SMART |
|
CA
|
264 |
348 |
7.6e-25 |
SMART |
|
CA
|
372 |
453 |
1.42e-24 |
SMART |
|
CA
|
477 |
568 |
5.38e-1 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192503
|
| SMART Domains |
Protein: ENSMUSP00000141989
Gene: ENSMUSG00000102312
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
17 |
N/A |
INTRINSIC |
|
CA
|
42 |
128 |
3.78e-2 |
SMART |
|
CA
|
152 |
237 |
8.94e-22 |
SMART |
|
CA
|
261 |
345 |
3.74e-24 |
SMART |
|
CA
|
369 |
450 |
1.09e-25 |
SMART |
|
CA
|
474 |
560 |
1.42e-24 |
SMART |
|
CA
|
588 |
670 |
2.96e-13 |
SMART |
|
transmembrane domain
|
692 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
910 |
934 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000192512
|
| SMART Domains |
Protein: ENSMUSP00000141408
Gene: ENSMUSG00000104252
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
20 |
131 |
5.3e-2 |
SMART |
|
CA
|
155 |
240 |
1.51e-19 |
SMART |
|
CA
|
264 |
348 |
7.6e-25 |
SMART |
|
CA
|
372 |
453 |
1.42e-24 |
SMART |
|
CA
|
477 |
563 |
1.42e-24 |
SMART |
|
CA
|
594 |
674 |
4.12e-12 |
SMART |
|
low complexity region
|
706 |
721 |
N/A |
INTRINSIC |
|
low complexity region
|
915 |
939 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000192631
AA Change: D557G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000142156
Gene: ENSMUSG00000104318
AA Change: D557G
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
21 |
131 |
2.58e-2 |
SMART |
|
CA
|
155 |
240 |
4.27e-19 |
SMART |
|
CA
|
264 |
348 |
1.42e-24 |
SMART |
|
CA
|
372 |
453 |
9.36e-25 |
SMART |
|
CA
|
477 |
563 |
1.42e-24 |
SMART |
|
CA
|
594 |
671 |
4.03e-6 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
low complexity region
|
905 |
929 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194501
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194544
|
| SMART Domains |
Protein: ENSMUSP00000141847
Gene: ENSMUSG00000102836
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:CA
|
18 |
66 |
5e-20 |
BLAST |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000194751
|
| SMART Domains |
Protein: ENSMUSP00000142285
Gene: ENSMUSG00000103707
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
15 |
21 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_2
|
29 |
112 |
4.5e-32 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193839
|
| SMART Domains |
Protein: ENSMUSP00000142308
Gene: ENSMUSG00000103442
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
22 |
132 |
3.09e-2 |
SMART |
|
CA
|
156 |
241 |
6.14e-20 |
SMART |
|
CA
|
265 |
349 |
3.92e-27 |
SMART |
|
CA
|
373 |
454 |
4.94e-24 |
SMART |
|
CA
|
478 |
564 |
1e-24 |
SMART |
|
CA
|
592 |
672 |
4.55e-14 |
SMART |
|
transmembrane domain
|
694 |
716 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193777
|
| SMART Domains |
Protein: ENSMUSP00000141587
Gene: ENSMUSG00000103707
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
21 |
131 |
5.67e-2 |
SMART |
|
CA
|
155 |
240 |
4.72e-21 |
SMART |
|
CA
|
264 |
348 |
1.9e-25 |
SMART |
|
CA
|
372 |
453 |
3.31e-25 |
SMART |
|
CA
|
477 |
563 |
1.42e-24 |
SMART |
|
CA
|
594 |
676 |
5.91e-13 |
SMART |
|
low complexity region
|
914 |
938 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193389
|
| SMART Domains |
Protein: ENSMUSP00000141459
Gene: ENSMUSG00000103707
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
21 |
131 |
5.67e-2 |
SMART |
|
CA
|
155 |
240 |
4.72e-21 |
SMART |
|
CA
|
264 |
348 |
1.9e-25 |
SMART |
|
CA
|
372 |
453 |
3.31e-25 |
SMART |
|
CA
|
477 |
563 |
1.42e-24 |
SMART |
|
CA
|
594 |
676 |
5.91e-13 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000195590
|
| SMART Domains |
Protein: ENSMUSP00000141355
Gene: ENSMUSG00000104148
| Domain | Start | End | E-Value | Type |
|---|
|
CA
|
45 |
131 |
6.34e-2 |
SMART |
|
CA
|
155 |
240 |
2.98e-18 |
SMART |
|
CA
|
264 |
348 |
2.17e-29 |
SMART |
|
CA
|
372 |
453 |
2.84e-24 |
SMART |
|
CA
|
477 |
563 |
5.02e-25 |
SMART |
|
CA
|
594 |
675 |
8.16e-16 |
SMART |
|
transmembrane domain
|
695 |
717 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000193984
|
| Meta Mutation Damage Score |
0.5949 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.1%
|
| Validation Efficiency |
100% (79/79) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene is a member of the protocadherin alpha gene cluster, one of three related gene clusters tandemly linked on chromosome five that demonstrate an unusual genomic organization similar to that of B-cell and T-cell receptor gene clusters. The alpha gene cluster is composed of 15 cadherin superfamily genes related to the mouse CNR genes and consists of 13 highly similar and 2 more distantly related coding sequences. The tandem array of 15 N-terminal exons, or variable exons, are followed by downstream C-terminal exons, or constant exons, which are shared by all genes in the cluster. The large, uninterrupted N-terminal exons each encode six cadherin ectodomains while the C-terminal exons encode the cytoplasmic domain. These neural cadherin-like cell adhesion proteins are integral plasma membrane proteins that most likely play a critical role in the establishment and function of specific cell-cell connections in the brain. Alternative splicing has been observed and additional variants have been suggested but their full-length nature has yet to be determined. [provided by RefSeq, Jul 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 73 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930402F06Rik |
C |
A |
2: 35,266,309 (GRCm39) |
M120I |
probably damaging |
Het |
| 4933427D14Rik |
A |
T |
11: 72,082,342 (GRCm39) |
L328Q |
probably damaging |
Het |
| Adgrv1 |
A |
C |
13: 81,709,704 (GRCm39) |
|
probably null |
Het |
| Ankrd46 |
A |
T |
15: 36,484,279 (GRCm39) |
|
probably benign |
Het |
| Arhgef18 |
A |
T |
8: 3,494,979 (GRCm39) |
M413L |
probably benign |
Het |
| Atp6v1e1 |
G |
A |
6: 120,781,044 (GRCm39) |
T87M |
probably null |
Het |
| Bap1 |
T |
C |
14: 30,980,402 (GRCm39) |
|
probably benign |
Het |
| Brf1 |
A |
G |
12: 112,929,507 (GRCm39) |
L385P |
probably benign |
Het |
| C1qtnf1 |
A |
T |
11: 118,338,938 (GRCm39) |
N203Y |
probably damaging |
Het |
| Catsperb |
A |
T |
12: 101,569,025 (GRCm39) |
N899I |
probably damaging |
Het |
| Ccnjl |
A |
C |
11: 43,470,718 (GRCm39) |
D162A |
probably damaging |
Het |
| Cd248 |
A |
C |
19: 5,119,195 (GRCm39) |
I348L |
probably benign |
Het |
| Cdc20 |
T |
C |
4: 118,293,029 (GRCm39) |
T265A |
probably benign |
Het |
| Cdca5 |
T |
A |
19: 6,140,427 (GRCm39) |
L196* |
probably null |
Het |
| Cdk4 |
T |
A |
10: 126,900,444 (GRCm39) |
|
probably benign |
Het |
| Cldn10 |
G |
A |
14: 119,025,725 (GRCm39) |
G53S |
possibly damaging |
Het |
| Clec4b2 |
G |
T |
6: 123,177,999 (GRCm39) |
E105* |
probably null |
Het |
| Dapk1 |
T |
A |
13: 60,909,600 (GRCm39) |
D1404E |
probably benign |
Het |
| Dnah1 |
T |
C |
14: 30,989,496 (GRCm39) |
Y3308C |
probably damaging |
Het |
| Dnah17 |
A |
C |
11: 117,969,419 (GRCm39) |
Y2260D |
probably damaging |
Het |
| Dock8 |
T |
G |
19: 25,159,001 (GRCm39) |
S1720A |
probably benign |
Het |
| Erc1 |
A |
G |
6: 119,754,947 (GRCm39) |
|
probably null |
Het |
| Ergic1 |
A |
G |
17: 26,848,597 (GRCm39) |
I66V |
probably benign |
Het |
| Fam186a |
T |
C |
15: 99,843,158 (GRCm39) |
T1029A |
possibly damaging |
Het |
| Fat4 |
A |
T |
3: 39,034,781 (GRCm39) |
Y2811F |
probably damaging |
Het |
| Flt3 |
A |
G |
5: 147,306,110 (GRCm39) |
M310T |
probably damaging |
Het |
| Ganab |
T |
A |
19: 8,892,355 (GRCm39) |
C844S |
probably benign |
Het |
| Gas2l2 |
C |
A |
11: 83,320,041 (GRCm39) |
V72F |
probably damaging |
Het |
| Gm14401 |
T |
A |
2: 176,778,573 (GRCm39) |
C220S |
probably damaging |
Het |
| Hmmr |
A |
T |
11: 40,619,261 (GRCm39) |
V73E |
probably benign |
Het |
| Idi2l |
T |
G |
13: 8,990,637 (GRCm39) |
|
probably benign |
Het |
| Ifih1 |
G |
T |
2: 62,465,358 (GRCm39) |
|
probably benign |
Het |
| Jak3 |
A |
G |
8: 72,138,048 (GRCm39) |
E833G |
probably damaging |
Het |
| Lama2 |
TTTGCGCATT |
TTT |
10: 26,919,639 (GRCm39) |
|
probably null |
Het |
| Ldb1 |
G |
A |
19: 46,023,132 (GRCm39) |
A217V |
probably benign |
Het |
| Lrrc8c |
A |
G |
5: 105,755,955 (GRCm39) |
T577A |
probably benign |
Het |
| Mfn1 |
T |
A |
3: 32,600,711 (GRCm39) |
|
probably benign |
Het |
| Mki67 |
G |
A |
7: 135,298,474 (GRCm39) |
P2187S |
probably damaging |
Het |
| Mrc1 |
T |
A |
2: 14,323,952 (GRCm39) |
D1096E |
probably benign |
Het |
| Msi1 |
A |
G |
5: 115,573,654 (GRCm39) |
|
probably benign |
Het |
| Msto1 |
T |
A |
3: 88,819,559 (GRCm39) |
I152F |
probably benign |
Het |
| Myo9a |
A |
G |
9: 59,803,800 (GRCm39) |
R2060G |
probably benign |
Het |
| Nnt |
A |
T |
13: 119,541,107 (GRCm39) |
C44* |
probably null |
Het |
| Nup210l |
A |
G |
3: 90,100,378 (GRCm39) |
D1468G |
probably damaging |
Het |
| Or1j16 |
T |
C |
2: 36,530,906 (GRCm39) |
L285P |
probably damaging |
Het |
| Or4c10b |
A |
G |
2: 89,711,476 (GRCm39) |
E102G |
probably benign |
Het |
| Or5d46 |
C |
A |
2: 88,174,686 (GRCm39) |
C129F |
possibly damaging |
Het |
| Or7a40 |
T |
C |
16: 16,491,482 (GRCm39) |
D121G |
probably damaging |
Het |
| P2rx3 |
G |
A |
2: 84,855,270 (GRCm39) |
T62I |
probably damaging |
Het |
| Pabpc4l |
G |
T |
3: 46,401,578 (GRCm39) |
T22K |
probably damaging |
Het |
| Pcdhb20 |
A |
G |
18: 37,639,298 (GRCm39) |
K608R |
possibly damaging |
Het |
| Pcnx1 |
A |
G |
12: 81,964,939 (GRCm39) |
S369G |
probably damaging |
Het |
| Plod1 |
T |
C |
4: 148,004,736 (GRCm39) |
I455V |
probably benign |
Het |
| Prune2 |
A |
T |
19: 17,099,219 (GRCm39) |
E1574D |
probably benign |
Het |
| Ptar1 |
T |
A |
19: 23,680,472 (GRCm39) |
L96H |
probably damaging |
Het |
| Rabgap1 |
T |
C |
2: 37,450,583 (GRCm39) |
S904P |
probably benign |
Het |
| Rps6ka4 |
C |
T |
19: 6,815,467 (GRCm39) |
V176I |
probably benign |
Het |
| Rufy4 |
T |
C |
1: 74,186,822 (GRCm39) |
C537R |
probably damaging |
Het |
| Runx1t1 |
T |
A |
4: 13,771,459 (GRCm39) |
M1K |
probably null |
Het |
| Serinc4 |
T |
A |
2: 121,282,905 (GRCm39) |
Y419F |
probably damaging |
Het |
| Serpina12 |
A |
T |
12: 104,004,056 (GRCm39) |
M192K |
possibly damaging |
Het |
| Spata21 |
T |
A |
4: 140,832,261 (GRCm39) |
M474K |
probably damaging |
Het |
| Stpg1 |
T |
C |
4: 135,246,676 (GRCm39) |
S135P |
possibly damaging |
Het |
| Tdrkh |
A |
G |
3: 94,336,671 (GRCm39) |
D481G |
probably damaging |
Het |
| Ube2e1 |
A |
C |
14: 18,285,268 (GRCm38) |
S68R |
probably damaging |
Het |
| Vcpip1 |
A |
C |
1: 9,817,572 (GRCm39) |
N270K |
probably damaging |
Het |
| Vmn2r79 |
T |
C |
7: 86,650,675 (GRCm39) |
F154L |
probably benign |
Het |
| Vwa3b |
A |
G |
1: 37,153,684 (GRCm39) |
|
probably benign |
Het |
| Xdh |
C |
A |
17: 74,207,703 (GRCm39) |
V885L |
probably benign |
Het |
| Zfp141 |
A |
T |
7: 42,125,629 (GRCm39) |
V281D |
probably benign |
Het |
| Zfp317 |
T |
A |
9: 19,558,143 (GRCm39) |
I119N |
probably benign |
Het |
| Zfp345 |
G |
A |
2: 150,314,608 (GRCm39) |
R310C |
probably benign |
Het |
| Zfp760 |
G |
A |
17: 21,942,229 (GRCm39) |
C468Y |
probably benign |
Het |
|
| Other mutations in Pcdha7 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
R2511:Pcdha7
|
UTSW |
18 |
37,107,786 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3881:Pcdha7
|
UTSW |
18 |
37,108,432 (GRCm39) |
missense |
probably benign |
0.44 |
|
R4212:Pcdha7
|
UTSW |
18 |
37,108,027 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4533:Pcdha7
|
UTSW |
18 |
37,108,460 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R4608:Pcdha7
|
UTSW |
18 |
37,108,870 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R4766:Pcdha7
|
UTSW |
18 |
37,107,560 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4808:Pcdha7
|
UTSW |
18 |
37,107,281 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5030:Pcdha7
|
UTSW |
18 |
37,108,501 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5173:Pcdha7
|
UTSW |
18 |
37,107,705 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5333:Pcdha7
|
UTSW |
18 |
37,107,619 (GRCm39) |
missense |
probably benign |
0.14 |
|
R5342:Pcdha7
|
UTSW |
18 |
37,107,724 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R5463:Pcdha7
|
UTSW |
18 |
37,108,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5536:Pcdha7
|
UTSW |
18 |
37,108,303 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5848:Pcdha7
|
UTSW |
18 |
37,108,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5858:Pcdha7
|
UTSW |
18 |
37,109,279 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5887:Pcdha7
|
UTSW |
18 |
37,108,960 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6115:Pcdha7
|
UTSW |
18 |
37,107,788 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6496:Pcdha7
|
UTSW |
18 |
37,107,638 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R6522:Pcdha7
|
UTSW |
18 |
37,106,995 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6653:Pcdha7
|
UTSW |
18 |
37,107,539 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6815:Pcdha7
|
UTSW |
18 |
37,108,174 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7313:Pcdha7
|
UTSW |
18 |
37,107,471 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7519:Pcdha7
|
UTSW |
18 |
37,109,285 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7520:Pcdha7
|
UTSW |
18 |
37,108,366 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7857:Pcdha7
|
UTSW |
18 |
37,108,892 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7939:Pcdha7
|
UTSW |
18 |
37,109,063 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8229:Pcdha7
|
UTSW |
18 |
37,107,776 (GRCm39) |
nonsense |
probably null |
|
|
R9592:Pcdha7
|
UTSW |
18 |
37,109,045 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9711:Pcdha7
|
UTSW |
18 |
37,107,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Pcdha7
|
UTSW |
18 |
37,108,893 (GRCm39) |
missense |
probably benign |
0.14 |
|
| Predicted Primers |
PCR Primer
(F):5'- GTCAGCGATGGATGCTGATG -3'
(R):5'- CAACTGGCTGCAGCTCAAAAG -3'
Sequencing Primer
(F):5'- AGAATGCGCTGGTGTCCTACTC -3'
(R):5'- GACAACCACGCATTGTATCCAGAG -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation