Mutagenetix > Incidental Mutation

Incidental Mutation 'R4898:Neurl4'

375944

Institutional Source

Beutler Lab

Gene Symbol

Neurl4

Ensembl Gene

ENSMUSG00000047284

Gene Name

neuralized E3 ubiquitin protein ligase 4

Synonyms

0610025P10Rik

MMRRC Submission

042502-MU

Accession Numbers

Essential gene?

Non essential (E-score: 0.000) question?

Stock #

R4898 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

69792545-69804648 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

A to G at 69793997 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Aspartic acid to Glycine at position 151 (D151G)

Ref Sequence

ENSEMBL: ENSMUSP00000135277 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000018714] [ENSMUST00000061837] [ENSMUST00000100969] [ENSMUST00000102580] [ENSMUST00000108617] [ENSMUST00000108621] [ENSMUST00000128046] [ENSMUST00000177138] [ENSMUST00000177476] [ENSMUST00000133203] [ENSMUST00000129234] [ENSMUST00000144431] [ENSMUST00000129475]

AlphaFold

Q5NCX5

Predicted Effect

probably benign
Transcript: ENSMUST00000018714

SMART Domains

Protein: ENSMUSP00000018714
Gene: ENSMUSG00000018570

Domain	Start	End	E-Value	Type
low complexity region	86	108	N/A	INTRINSIC
low complexity region	115	127	N/A	INTRINSIC
low complexity region	132	144	N/A	INTRINSIC
Pfam:IPP-2	150	277	1.3e-44	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000061837
AA Change: D151G

PolyPhen 2 Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000053235
Gene: ENSMUSG00000047284
AA Change: D151G

Domain	Start	End	E-Value	Type
low complexity region	3	44	N/A	INTRINSIC
NEUZ	47	165	1.02e-28	SMART
low complexity region	207	237	N/A	INTRINSIC
NEUZ	317	442	7.22e-52	SMART
low complexity region	492	503	N/A	INTRINSIC
NEUZ	520	644	6.15e-46	SMART
low complexity region	686	700	N/A	INTRINSIC
NEUZ	716	840	7.81e-39	SMART
NEUZ	913	1043	2.27e-17	SMART
low complexity region	1108	1117	N/A	INTRINSIC
NEUZ	1130	1250	4.93e-6	SMART
low complexity region	1453	1464	N/A	INTRINSIC
low complexity region	1474	1483	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000100969

SMART Domains

Protein: ENSMUSP00000098529
Gene: ENSMUSG00000018570

Domain	Start	End	E-Value	Type
low complexity region	86	108	N/A	INTRINSIC
low complexity region	115	127	N/A	INTRINSIC
low complexity region	132	144	N/A	INTRINSIC
Pfam:IPP-2	150	272	5.7e-41	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000102580

SMART Domains

Protein: ENSMUSP00000099640
Gene: ENSMUSG00000018570

Domain	Start	End	E-Value	Type
low complexity region	86	108	N/A	INTRINSIC
low complexity region	115	127	N/A	INTRINSIC
low complexity region	132	144	N/A	INTRINSIC
Pfam:IPP-2	153	270	6.2e-31	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000108617
AA Change: D151G

PolyPhen 2 Score 0.964 (Sensitivity: 0.78; Specificity: 0.95)

SMART Domains

Protein: ENSMUSP00000104257
Gene: ENSMUSG00000047284
AA Change: D151G

Domain	Start	End	E-Value	Type
low complexity region	3	44	N/A	INTRINSIC
NEUZ	47	165	3.5e-31	SMART
low complexity region	207	237	N/A	INTRINSIC
NEUZ	295	420	2.5e-54	SMART
low complexity region	470	481	N/A	INTRINSIC
NEUZ	498	622	2e-48	SMART
low complexity region	664	678	N/A	INTRINSIC
NEUZ	694	818	2.6e-41	SMART
NEUZ	891	1021	7.6e-20	SMART
low complexity region	1086	1095	N/A	INTRINSIC
NEUZ	1108	1228	1.7e-8	SMART
low complexity region	1431	1442	N/A	INTRINSIC
low complexity region	1452	1461	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000108621

SMART Domains

Protein: ENSMUSP00000104261
Gene: ENSMUSG00000018570

Domain	Start	End	E-Value	Type
low complexity region	86	108	N/A	INTRINSIC
low complexity region	115	127	N/A	INTRINSIC
low complexity region	132	144	N/A	INTRINSIC
Pfam:IPP-2	150	277	1.3e-44	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000128046

SMART Domains

Protein: ENSMUSP00000137547
Gene: ENSMUSG00000018570

Domain	Start	End	E-Value	Type
Pfam:IPP-2	1	77	1.7e-26	PFAM

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000175742

Predicted Effect

probably damaging
Transcript: ENSMUST00000177138
AA Change: D151G

PolyPhen 2 Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000135277
Gene: ENSMUSG00000047284
AA Change: D151G

Domain	Start	End	E-Value	Type
low complexity region	3	44	N/A	INTRINSIC
NEUZ	47	165	1.02e-28	SMART
low complexity region	207	237	N/A	INTRINSIC
NEUZ	295	420	7.22e-52	SMART
low complexity region	470	481	N/A	INTRINSIC
NEUZ	498	622	6.15e-46	SMART
low complexity region	664	678	N/A	INTRINSIC
NEUZ	694	818	7.81e-39	SMART
NEUZ	889	1019	2.27e-17	SMART
low complexity region	1084	1093	N/A	INTRINSIC
NEUZ	1106	1226	4.93e-6	SMART
low complexity region	1429	1440	N/A	INTRINSIC
low complexity region	1450	1459	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000177160

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000176614

Predicted Effect

probably damaging
Transcript: ENSMUST00000177476
AA Change: D151G

PolyPhen 2 Score 0.983 (Sensitivity: 0.75; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000135185
Gene: ENSMUSG00000047284
AA Change: D151G

Domain	Start	End	E-Value	Type
low complexity region	3	44	N/A	INTRINSIC
NEUZ	47	165	1.02e-28	SMART
low complexity region	207	237	N/A	INTRINSIC
NEUZ	317	442	7.22e-52	SMART
low complexity region	492	503	N/A	INTRINSIC
NEUZ	520	644	6.15e-46	SMART
low complexity region	686	700	N/A	INTRINSIC
NEUZ	716	840	7.81e-39	SMART
NEUZ	911	1041	2.27e-17	SMART
low complexity region	1106	1115	N/A	INTRINSIC
NEUZ	1128	1248	4.93e-6	SMART
low complexity region	1451	1462	N/A	INTRINSIC
low complexity region	1472	1481	N/A	INTRINSIC

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000142121

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000153041

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000137122

Predicted Effect

probably benign
Transcript: ENSMUST00000133203

SMART Domains

Protein: ENSMUSP00000117917
Gene: ENSMUSG00000047284

Domain	Start	End	E-Value	Type
NEUZ	60	185	7.22e-52	SMART
low complexity region	235	246	N/A	INTRINSIC
NEUZ	263	387	6.15e-46	SMART
low complexity region	429	443	N/A	INTRINSIC
NEUZ	459	583	7.81e-39	SMART
NEUZ	656	786	2.27e-17	SMART
low complexity region	851	860	N/A	INTRINSIC
Pfam:Neuralized	875	942	6.5e-10	PFAM

Predicted Effect

probably benign
Transcript: ENSMUST00000129234

SMART Domains

Protein: ENSMUSP00000136835
Gene: ENSMUSG00000018570

Domain	Start	End	E-Value	Type
low complexity region	86	108	N/A	INTRINSIC
low complexity region	115	127	N/A	INTRINSIC
low complexity region	132	144	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000144431

SMART Domains

Protein: ENSMUSP00000135926
Gene: ENSMUSG00000018570

Domain	Start	End	E-Value	Type
low complexity region	86	108	N/A	INTRINSIC
low complexity region	115	127	N/A	INTRINSIC
low complexity region	132	144	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000129475

SMART Domains

Protein: ENSMUSP00000135733
Gene: ENSMUSG00000047284

Domain	Start	End	E-Value	Type
NEUZ	1	119	4.22e-44	SMART
low complexity region	169	180	N/A	INTRINSIC
low complexity region	182	201	N/A	INTRINSIC
internal_repeat_1	206	246	1.46e-10	PROSPERO

Coding Region Coverage

1x: 99.1%
3x: 98.5%
10x: 96.8%
20x: 93.9%

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is predicted and it includes two isoforms resulting from two alternatively spliced transcript variants. [provided by RefSeq, Jul 2008]

Allele List at MGI

Other mutations in this stock

Total: 116 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abcc6	T	C	7: 45,639,111 (GRCm39)	Y944C	probably damaging	Het
Acacb	T	C	5: 114,370,999 (GRCm39)	V1747A	probably benign	Het
Acad8	C	T	9: 26,889,698 (GRCm39)	R332H	probably damaging	Het
Acrbp	A	C	6: 125,027,501 (GRCm39)	T50P	probably damaging	Het
Ahctf1	G	T	1: 179,583,077 (GRCm39)	N1500K	probably benign	Het
Aoc1l3	A	G	6: 48,964,651 (GRCm39)	T220A	possibly damaging	Het
Arfgef1	A	G	1: 10,229,798 (GRCm39)	I1301T	possibly damaging	Het
Arhgef15	T	C	11: 68,842,171 (GRCm39)	S478G	probably benign	Het
Armh1	T	C	4: 117,094,977 (GRCm39)	D21G	probably damaging	Het
Atp13a4	A	T	16: 29,227,779 (GRCm39)	L1045*	probably null	Het
Atp2a3	T	A	11: 72,873,506 (GRCm39)	L793H	probably damaging	Het
B4galnt4	C	A	7: 140,648,173 (GRCm39)	P563Q	probably benign	Het
Bcl2a1b	A	T	9: 89,081,713 (GRCm39)	K94*	probably null	Het
Bod1	T	A	11: 31,616,853 (GRCm39)	Q136L	possibly damaging	Het
C2cd3	A	G	7: 100,055,166 (GRCm39)	K443R	probably damaging	Het
Cadps	A	G	14: 12,411,588 (GRCm38)	V1250A	possibly damaging	Het
Car12	T	A	9: 66,671,600 (GRCm39)	Y332*	probably null	Het
Ccdc186	A	T	19: 56,790,432 (GRCm39)		probably null	Het
Cdh6	T	C	15: 13,034,774 (GRCm39)	T629A	probably damaging	Het
Cep112	T	A	11: 108,397,471 (GRCm39)	D353E	probably damaging	Het
Cep152	T	C	2: 125,428,301 (GRCm39)	S777G	probably benign	Het
Clec4b2	A	C	6: 123,181,163 (GRCm39)	K183Q	probably benign	Het
Cngb3	T	C	4: 19,395,926 (GRCm39)	Y323H	probably benign	Het
Cnp	G	T	11: 100,467,202 (GRCm39)	E48D	probably benign	Het
Ctrb1	T	A	8: 112,413,783 (GRCm39)	I194F	probably benign	Het
Cyp2d11	T	A	15: 82,275,224 (GRCm39)	D241V	probably benign	Het
D5Ertd579e	T	A	5: 36,772,285 (GRCm39)	E703D	probably damaging	Het
Dlg1	T	C	16: 31,676,764 (GRCm39)	V731A	probably damaging	Het
Dlgap5	T	C	14: 47,651,276 (GRCm39)	S86G	probably benign	Het
Dock3	A	G	9: 106,807,266 (GRCm39)	F1354L	probably damaging	Het
Dock3	C	A	9: 106,870,171 (GRCm39)	V638F	possibly damaging	Het
Eif3c	A	T	7: 126,156,626 (GRCm39)	M407K	probably benign	Het
Eif4a3l1	A	T	6: 136,305,737 (GRCm39)	Q66L	possibly damaging	Het
Epha4	T	A	1: 77,366,712 (GRCm39)	K578*	probably null	Het
Erc2	C	T	14: 27,375,285 (GRCm39)	L168F	probably damaging	Het
Esyt2	A	G	12: 116,305,708 (GRCm39)	I313V	probably benign	Het
Far1	T	A	7: 113,167,432 (GRCm39)	Y506N	probably damaging	Het
Fbxw26	T	A	9: 109,547,037 (GRCm39)	N463Y	possibly damaging	Het
Fgg	A	G	3: 82,915,847 (GRCm39)	D96G	probably benign	Het
Gfer	A	G	17: 24,914,274 (GRCm39)	S130P	probably damaging	Het
Hdac10	A	T	15: 89,012,650 (GRCm39)	M1K	probably null	Het
Hsd3b1	A	T	3: 98,760,642 (GRCm39)	S110R	probably benign	Het
Ints15	A	G	5: 143,287,592 (GRCm39)	S438P	probably benign	Het
Itga6	T	C	2: 71,668,717 (GRCm39)	L552P	possibly damaging	Het
Klk14	G	A	7: 43,341,501 (GRCm39)	C51Y	probably damaging	Het
Lama2	TTTGCGCATT	TTT	10: 26,919,639 (GRCm39)		probably null	Het
Llgl1	C	T	11: 60,600,394 (GRCm39)	P581L	probably benign	Het
Lrrc8a	A	G	2: 30,147,214 (GRCm39)	K676R	probably benign	Het
Lrrc8b	A	T	5: 105,628,080 (GRCm39)	Y142F	probably benign	Het
Lyz2	T	A	10: 117,114,614 (GRCm39)	D105V	possibly damaging	Het
Mamdc4	T	C	2: 25,460,035 (GRCm39)	D76G	probably damaging	Het
Map7d1	T	C	4: 126,127,018 (GRCm39)	K731E	unknown	Het
Mgam	A	C	6: 40,619,988 (GRCm39)	I26L	probably benign	Het
Mmp13	A	T	9: 7,272,953 (GRCm39)	E104D	probably benign	Het
Morc2a	C	T	11: 3,626,664 (GRCm39)	R241*	probably null	Het
Mtfmt	C	A	9: 65,359,386 (GRCm39)	H354N	probably benign	Het
Myh3	T	C	11: 66,990,233 (GRCm39)	I1626T	probably benign	Het
Ndst1	A	T	18: 60,825,059 (GRCm39)	V753D	probably benign	Het
Nlrx1	T	C	9: 44,168,194 (GRCm39)	S568G	probably benign	Het
Or10g3b	G	C	14: 52,586,999 (GRCm39)	P168R	probably damaging	Het
Or2t45	T	C	11: 58,669,132 (GRCm39)	Y60H	possibly damaging	Het
Or2t46	T	G	11: 58,472,546 (GRCm39)	L292R	probably damaging	Het
Or4c52	T	C	2: 89,845,762 (GRCm39)	F163L	probably damaging	Het
Or52s1	A	G	7: 102,861,747 (GRCm39)	I216V	probably damaging	Het
Or6c66	A	T	10: 129,461,468 (GRCm39)	I154N	probably benign	Het
Or8b42	A	T	9: 38,342,111 (GRCm39)	M178L	probably benign	Het
Osbpl7	A	G	11: 96,950,976 (GRCm39)	I608V	probably damaging	Het
Pard3b	T	C	1: 61,807,159 (GRCm39)	I58T	probably damaging	Het
Pcare	A	G	17: 72,058,066 (GRCm39)	M537T	probably damaging	Het
Pcdhga1	A	C	18: 37,795,407 (GRCm39)	E137A	possibly damaging	Het
Pde6c	G	A	19: 38,139,072 (GRCm39)	V301I	possibly damaging	Het
Pdia5	G	C	16: 35,230,786 (GRCm39)	N338K	possibly damaging	Het
Pex11g	T	C	8: 3,514,042 (GRCm39)	Y40C	probably damaging	Het
Plekhg3	A	G	12: 76,610,899 (GRCm39)	Y183C	probably damaging	Het
Pole	A	C	5: 110,438,090 (GRCm39)		probably null	Het
Ppfia1	A	G	7: 144,045,313 (GRCm39)	L948P	probably damaging	Het
Prdm2	A	T	4: 142,860,761 (GRCm39)	V843E	probably damaging	Het
Prss56	C	A	1: 87,115,708 (GRCm39)	F527L	probably damaging	Het
Psmd11	T	C	11: 80,329,146 (GRCm39)	L88P	probably damaging	Het
Ptx3	G	C	3: 66,132,412 (GRCm39)	G311A	probably damaging	Het
Rars1	A	T	11: 35,699,385 (GRCm39)	L636H	probably damaging	Het
Rnft2	A	G	5: 118,375,507 (GRCm39)	S81P	probably benign	Het
Rufy4	T	C	1: 74,186,822 (GRCm39)	C537R	probably damaging	Het
Rxra	T	A	2: 27,631,195 (GRCm39)	I142N	probably damaging	Het
Scin	T	C	12: 40,154,931 (GRCm39)	M221V	probably benign	Het
Sfmbt2	G	A	2: 10,584,069 (GRCm39)	V809I	possibly damaging	Het
Sirt1	T	A	10: 63,157,783 (GRCm39)	I505F	probably benign	Het
Six5	T	C	7: 18,829,096 (GRCm39)	Y179H	probably damaging	Het
Slc12a4	A	C	8: 106,671,241 (GRCm39)	M982R	probably damaging	Het
Slco4c1	T	A	1: 96,765,237 (GRCm39)	L404F	probably damaging	Het
Smn1	T	C	13: 100,268,931 (GRCm39)	L259P	probably damaging	Het
Sorl1	T	G	9: 41,952,935 (GRCm39)	D702A	probably damaging	Het
Spta1	A	G	1: 174,065,400 (GRCm39)	E1983G	possibly damaging	Het
Srsf1	T	A	11: 87,940,788 (GRCm39)		probably null	Het
Stard9	C	T	2: 120,536,900 (GRCm39)	R4224*	probably null	Het
Sybu	T	G	15: 44,538,895 (GRCm39)	M383L	probably benign	Het
Tbx15	A	C	3: 99,259,583 (GRCm39)	N485H	possibly damaging	Het
Tcerg1l	A	T	7: 137,819,786 (GRCm39)	F485I	probably damaging	Het
Tdrd7	C	A	4: 46,005,616 (GRCm39)	T474N	possibly damaging	Het
Thada	A	T	17: 84,755,470 (GRCm39)		probably null	Het
Tnik	A	T	3: 28,704,235 (GRCm39)	I1020F	probably damaging	Het
Tnxb	A	G	17: 34,914,566 (GRCm39)	D1884G	possibly damaging	Het
Tprn	T	C	2: 25,158,845 (GRCm39)	M623T	probably damaging	Het
Trdn	T	A	10: 33,350,413 (GRCm39)	Y661N	probably damaging	Het
Ttc41	T	C	10: 86,612,056 (GRCm39)	S1110P	possibly damaging	Het
Ttc6	A	C	12: 57,707,026 (GRCm39)	R644S	probably benign	Het
Ttyh1	A	T	7: 4,136,735 (GRCm39)	M448L	probably benign	Het
Unc79	G	T	12: 103,128,079 (GRCm39)	C2250F	probably damaging	Het
Ush2a	A	G	1: 188,358,805 (GRCm39)	I2110M	probably benign	Het
Uvssa	G	T	5: 33,571,257 (GRCm39)	E634*	probably null	Het
Vac14	A	C	8: 111,372,440 (GRCm39)	T384P	probably benign	Het
Wdr11	A	G	7: 129,235,445 (GRCm39)	E1169G	probably benign	Het
Zfp36l1	T	A	12: 80,157,298 (GRCm39)	T28S	probably benign	Het
Zfp715	A	T	7: 42,949,106 (GRCm39)	Y285N	possibly damaging	Het
Zfp91	A	T	19: 12,747,424 (GRCm39)	D566E	probably damaging	Het
Zgrf1	G	A	3: 127,396,085 (GRCm39)	V544M	probably damaging	Het

Other mutations in Neurl4

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00339:Neurl4	APN	11	69,795,413 (GRCm39)	missense	probably damaging	1.00
IGL00516:Neurl4	APN	11	69,801,219 (GRCm39)	missense	probably damaging	0.98
IGL01409:Neurl4	APN	11	69,797,925 (GRCm39)	missense	probably damaging	1.00
IGL01951:Neurl4	APN	11	69,800,449 (GRCm39)	missense	probably damaging	1.00
IGL02056:Neurl4	APN	11	69,796,616 (GRCm39)	missense	probably damaging	1.00
IGL02206:Neurl4	APN	11	69,801,166 (GRCm39)	missense	probably damaging	1.00
IGL02557:Neurl4	APN	11	69,797,161 (GRCm39)	missense	probably damaging	1.00
IGL02878:Neurl4	APN	11	69,797,657 (GRCm39)	missense	probably damaging	1.00
P0022:Neurl4	UTSW	11	69,799,891 (GRCm39)	missense	possibly damaging	0.86
PIT4377001:Neurl4	UTSW	11	69,801,232 (GRCm39)	missense	probably benign	0.41
R0388:Neurl4	UTSW	11	69,802,559 (GRCm39)	splice site	probably benign
R0421:Neurl4	UTSW	11	69,799,360 (GRCm39)	missense	probably damaging	1.00
R0449:Neurl4	UTSW	11	69,796,393 (GRCm39)	missense	probably damaging	0.99
R1174:Neurl4	UTSW	11	69,794,547 (GRCm39)	critical splice donor site	probably null
R1345:Neurl4	UTSW	11	69,794,702 (GRCm39)	missense	probably benign	0.21
R1536:Neurl4	UTSW	11	69,794,252 (GRCm39)	nonsense	probably null
R1642:Neurl4	UTSW	11	69,794,485 (GRCm39)	missense	probably benign	0.03
R1857:Neurl4	UTSW	11	69,796,361 (GRCm39)	missense	probably damaging	1.00
R1935:Neurl4	UTSW	11	69,797,959 (GRCm39)	missense	probably damaging	1.00
R1936:Neurl4	UTSW	11	69,797,959 (GRCm39)	missense	probably damaging	1.00
R1967:Neurl4	UTSW	11	69,794,036 (GRCm39)	missense	possibly damaging	0.90
R1973:Neurl4	UTSW	11	69,800,118 (GRCm39)	missense	probably benign
R2046:Neurl4	UTSW	11	69,799,523 (GRCm39)	missense	probably damaging	1.00
R2165:Neurl4	UTSW	11	69,794,047 (GRCm39)	missense	probably benign
R2393:Neurl4	UTSW	11	69,797,900 (GRCm39)	missense	probably damaging	1.00
R3810:Neurl4	UTSW	11	69,794,859 (GRCm39)	missense	probably damaging	1.00
R4299:Neurl4	UTSW	11	69,799,887 (GRCm39)	missense	probably damaging	1.00
R4749:Neurl4	UTSW	11	69,801,894 (GRCm39)	missense	probably benign	0.00
R4968:Neurl4	UTSW	11	69,798,134 (GRCm39)	missense	probably damaging	1.00
R4969:Neurl4	UTSW	11	69,801,913 (GRCm39)	missense	probably damaging	1.00
R5503:Neurl4	UTSW	11	69,797,194 (GRCm39)	missense	probably damaging	1.00
R6655:Neurl4	UTSW	11	69,801,742 (GRCm39)	critical splice donor site	probably null
R6791:Neurl4	UTSW	11	69,799,336 (GRCm39)	missense	probably damaging	1.00
R7029:Neurl4	UTSW	11	69,801,562 (GRCm39)	missense	probably damaging	0.99
R7216:Neurl4	UTSW	11	69,801,088 (GRCm39)	missense	probably damaging	1.00
R7361:Neurl4	UTSW	11	69,802,905 (GRCm39)	missense	probably benign	0.01
R7367:Neurl4	UTSW	11	69,799,408 (GRCm39)	missense	probably damaging	1.00
R7804:Neurl4	UTSW	11	69,796,700 (GRCm39)	missense	probably benign	0.00
R7871:Neurl4	UTSW	11	69,794,012 (GRCm39)	missense	probably benign
R8092:Neurl4	UTSW	11	69,801,891 (GRCm39)	missense	probably benign
R8121:Neurl4	UTSW	11	69,799,056 (GRCm39)	splice site	probably null
R8131:Neurl4	UTSW	11	69,800,067 (GRCm39)	missense	probably benign	0.12
R8289:Neurl4	UTSW	11	69,800,206 (GRCm39)	critical splice donor site	probably null
R8354:Neurl4	UTSW	11	69,800,062 (GRCm39)	missense	probably damaging	0.97
R8494:Neurl4	UTSW	11	69,801,871 (GRCm39)	missense	probably benign	0.02
R8529:Neurl4	UTSW	11	69,799,613 (GRCm39)	missense	probably damaging	1.00
R8850:Neurl4	UTSW	11	69,794,788 (GRCm39)	unclassified	probably benign
R8992:Neurl4	UTSW	11	69,798,958 (GRCm39)	missense	possibly damaging	0.69
R9334:Neurl4	UTSW	11	69,796,792 (GRCm39)	missense	probably damaging	1.00
R9509:Neurl4	UTSW	11	69,792,971 (GRCm39)	nonsense	probably null
R9705:Neurl4	UTSW	11	69,799,679 (GRCm39)	missense	probably damaging	0.97
R9707:Neurl4	UTSW	11	69,799,679 (GRCm39)	missense	probably damaging	0.97
R9746:Neurl4	UTSW	11	69,798,301 (GRCm39)	missense	probably damaging	1.00
X0025:Neurl4	UTSW	11	69,797,627 (GRCm39)	missense	probably damaging	1.00
Z1177:Neurl4	UTSW	11	69,794,916 (GRCm39)	missense	possibly damaging	0.65

Predicted Primers

PCR Primer
(F):5'- TAGGTCAACTCCTGGAGTGG -3'
(R):5'- ACAGGGCTGAATCTTCTGGAG -3'

Sequencing Primer
(F):5'- GCTCCATTGAGATTGGAGTGACAG -3'
(R):5'- CTGAATCTTCTGGAGGGGCC -3'

Posted On

2016-03-17