Incidental Mutation 'R4868:Tnn'
| ID |
376288 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Tnn
|
| Ensembl Gene |
ENSMUSG00000026725 |
| Gene Name |
tenascin N |
| Synonyms |
tenascin-W, Tnw |
| MMRRC Submission |
042478-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.298)
|
| Stock # |
R4868 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
159912599-159981150 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 159958443 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Glycine
at position 467
(R467G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000039452
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039178]
[ENSMUST00000131919]
|
| AlphaFold |
Q80Z71 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000039178
AA Change: R467G
PolyPhen 2
Score 0.645 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000039452
Gene: ENSMUSG00000026725
AA Change: R467G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.34e-9 |
SMART |
|
FN3
|
883 |
960 |
9.04e-9 |
SMART |
|
FN3
|
971 |
1048 |
1.07e-10 |
SMART |
|
FN3
|
1059 |
1136 |
7.57e-11 |
SMART |
|
FN3
|
1147 |
1224 |
4.59e-10 |
SMART |
|
FN3
|
1235 |
1312 |
1.95e-4 |
SMART |
|
FBG
|
1327 |
1539 |
1.16e-114 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000131919
AA Change: R467G
PolyPhen 2
Score 0.217 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000115685
Gene: ENSMUSG00000026725
AA Change: R467G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
26 |
N/A |
INTRINSIC |
|
coiled coil region
|
100 |
132 |
N/A |
INTRINSIC |
|
EGF_like
|
170 |
198 |
3.5e1 |
SMART |
|
EGF
|
201 |
229 |
2.29e1 |
SMART |
|
EGF_like
|
232 |
260 |
2.86e1 |
SMART |
|
FN3
|
262 |
341 |
1.81e-8 |
SMART |
|
FN3
|
351 |
432 |
1.08e-6 |
SMART |
|
FN3
|
443 |
521 |
1.19e-8 |
SMART |
|
FN3
|
531 |
608 |
2.64e-10 |
SMART |
|
FN3
|
619 |
696 |
1.6e-9 |
SMART |
|
FN3
|
707 |
784 |
9.04e-9 |
SMART |
|
FN3
|
795 |
872 |
7.57e-11 |
SMART |
|
FN3
|
883 |
960 |
4.59e-10 |
SMART |
|
FN3
|
971 |
1048 |
1.95e-4 |
SMART |
|
FBG
|
1063 |
1275 |
1.16e-114 |
SMART |
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.1%
- 20x: 94.7%
|
| Validation Efficiency |
99% (91/92) |
| Allele List at MGI |
All alleles(2) : Targeted, other(2)
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933405L10Rik |
A |
G |
8: 106,436,729 (GRCm39) |
*299W |
probably null |
Het |
| 4933412E24Rik |
G |
A |
15: 59,887,817 (GRCm39) |
L208F |
possibly damaging |
Het |
| Abca8b |
G |
A |
11: 109,865,338 (GRCm39) |
A373V |
probably benign |
Het |
| Actn3 |
A |
T |
19: 4,914,482 (GRCm39) |
W549R |
probably benign |
Het |
| Adamts4 |
C |
T |
1: 171,080,000 (GRCm39) |
|
probably benign |
Het |
| Adcy4 |
T |
C |
14: 56,011,179 (GRCm39) |
I615V |
probably benign |
Het |
| Akap1 |
A |
G |
11: 88,735,379 (GRCm39) |
S428P |
possibly damaging |
Het |
| Akap13 |
A |
T |
7: 75,393,252 (GRCm39) |
R2476W |
probably damaging |
Het |
| Alx3 |
A |
G |
3: 107,507,943 (GRCm39) |
S151G |
possibly damaging |
Het |
| Aoah |
T |
A |
13: 21,099,151 (GRCm39) |
Y243* |
probably null |
Het |
| Asap1 |
A |
G |
15: 63,966,030 (GRCm39) |
V1025A |
probably benign |
Het |
| Atp8b1 |
A |
T |
18: 64,684,937 (GRCm39) |
I728N |
probably damaging |
Het |
| Baz2b |
C |
A |
2: 59,755,226 (GRCm39) |
V1001L |
possibly damaging |
Het |
| Bmpr2 |
T |
A |
1: 59,909,615 (GRCm39) |
S1030T |
probably benign |
Het |
| Cacna2d3 |
A |
T |
14: 28,678,743 (GRCm39) |
|
probably null |
Het |
| Casp3 |
A |
T |
8: 47,087,314 (GRCm39) |
N87I |
probably benign |
Het |
| Ccdc171 |
T |
A |
4: 83,612,569 (GRCm39) |
L995Q |
probably damaging |
Het |
| Ccdc80 |
T |
A |
16: 44,924,776 (GRCm39) |
Y637N |
probably damaging |
Het |
| Ccr4 |
A |
G |
9: 114,321,901 (GRCm39) |
F55L |
probably benign |
Het |
| Cmah |
T |
A |
13: 24,648,247 (GRCm39) |
V494E |
probably damaging |
Het |
| Cnot6l |
A |
G |
5: 96,230,882 (GRCm39) |
Y362H |
probably damaging |
Het |
| Coq6 |
T |
C |
12: 84,417,726 (GRCm39) |
V222A |
probably damaging |
Het |
| Ctdspl2 |
C |
A |
2: 121,823,879 (GRCm39) |
T240N |
possibly damaging |
Het |
| D430041D05Rik |
T |
C |
2: 104,085,754 (GRCm39) |
T248A |
possibly damaging |
Het |
| Dctn6 |
A |
T |
8: 34,559,230 (GRCm39) |
|
probably benign |
Het |
| Dhx34 |
T |
C |
7: 15,933,727 (GRCm39) |
D955G |
probably benign |
Het |
| Dnaaf5 |
A |
G |
5: 139,155,941 (GRCm39) |
M541V |
probably benign |
Het |
| Dnah17 |
A |
T |
11: 117,999,038 (GRCm39) |
S912T |
probably benign |
Het |
| Dnah2 |
A |
T |
11: 69,354,474 (GRCm39) |
V2248E |
probably damaging |
Het |
| Dysf |
T |
C |
6: 84,156,675 (GRCm39) |
W1502R |
probably damaging |
Het |
| Dzip1 |
A |
T |
14: 119,114,626 (GRCm39) |
V843E |
probably damaging |
Het |
| Esp23 |
G |
T |
17: 39,384,915 (GRCm39) |
T27K |
probably benign |
Het |
| Esp3 |
A |
T |
17: 40,944,420 (GRCm39) |
M21L |
possibly damaging |
Het |
| Fam43b |
T |
A |
4: 138,123,108 (GRCm39) |
T71S |
probably benign |
Het |
| Fpgs |
G |
A |
2: 32,582,673 (GRCm39) |
R63C |
probably damaging |
Het |
| H2-M11 |
G |
T |
17: 36,859,811 (GRCm39) |
W268L |
probably damaging |
Het |
| Inpp5b |
T |
C |
4: 124,645,203 (GRCm39) |
S210P |
probably damaging |
Het |
| Itsn1 |
T |
A |
16: 91,582,205 (GRCm39) |
S51T |
probably damaging |
Het |
| Kctd2 |
G |
A |
11: 115,320,205 (GRCm39) |
V246I |
probably damaging |
Het |
| Krt75 |
C |
T |
15: 101,476,556 (GRCm39) |
G403E |
probably damaging |
Het |
| Lamp3 |
T |
A |
16: 19,520,040 (GRCm39) |
T48S |
probably benign |
Het |
| Lyzl4 |
C |
A |
9: 121,412,075 (GRCm39) |
V114L |
probably damaging |
Het |
| Maml3 |
C |
A |
3: 52,011,345 (GRCm39) |
E74* |
probably null |
Het |
| Map2k7 |
G |
A |
8: 4,297,751 (GRCm39) |
|
probably benign |
Het |
| Mapk8ip3 |
A |
G |
17: 25,120,389 (GRCm39) |
V883A |
probably benign |
Het |
| Mbtps1 |
C |
T |
8: 120,235,667 (GRCm39) |
V1004I |
probably benign |
Het |
| Metap1 |
G |
T |
3: 138,188,850 (GRCm39) |
H48Q |
probably damaging |
Het |
| Mical2 |
T |
A |
7: 111,917,831 (GRCm39) |
V396E |
probably damaging |
Het |
| Mks1 |
T |
A |
11: 87,744,549 (GRCm39) |
|
probably benign |
Het |
| Ndst1 |
T |
C |
18: 60,828,548 (GRCm39) |
T669A |
probably benign |
Het |
| Obox3 |
T |
C |
7: 15,361,235 (GRCm39) |
K10R |
probably damaging |
Het |
| Opn3 |
T |
C |
1: 175,491,127 (GRCm39) |
Y302C |
probably damaging |
Het |
| Or4f62 |
T |
A |
2: 111,986,916 (GRCm39) |
S207T |
probably damaging |
Het |
| Or6b6 |
C |
T |
7: 106,570,974 (GRCm39) |
M192I |
probably benign |
Het |
| Or9g8 |
T |
G |
2: 85,606,970 (GRCm39) |
V14G |
possibly damaging |
Het |
| Pdzph1 |
A |
T |
17: 59,281,751 (GRCm39) |
V177D |
probably benign |
Het |
| Pex5l |
T |
A |
3: 33,006,639 (GRCm39) |
I577F |
probably damaging |
Het |
| Pmpcb |
T |
A |
5: 21,953,851 (GRCm39) |
Y366* |
probably null |
Het |
| Prr14l |
A |
T |
5: 32,987,281 (GRCm39) |
M738K |
probably benign |
Het |
| Prx |
T |
C |
7: 27,217,004 (GRCm39) |
S641P |
probably benign |
Het |
| Ptchd3 |
A |
G |
11: 121,721,883 (GRCm39) |
Y252C |
possibly damaging |
Het |
| Reg3a |
A |
G |
6: 78,358,883 (GRCm39) |
E27G |
probably damaging |
Het |
| Ripor2 |
A |
G |
13: 24,878,124 (GRCm39) |
T300A |
possibly damaging |
Het |
| Sdf4 |
T |
A |
4: 156,093,642 (GRCm39) |
S259T |
probably damaging |
Het |
| Sike1 |
A |
G |
3: 102,904,730 (GRCm39) |
|
probably null |
Het |
| Sis |
T |
G |
3: 72,850,881 (GRCm39) |
I606L |
probably benign |
Het |
| Slc30a9 |
T |
C |
5: 67,482,026 (GRCm39) |
I94T |
probably benign |
Het |
| Slc5a4a |
T |
C |
10: 76,014,065 (GRCm39) |
I424T |
probably damaging |
Het |
| Spx |
C |
T |
6: 142,362,116 (GRCm39) |
R72* |
probably null |
Het |
| St7 |
C |
A |
6: 17,819,265 (GRCm39) |
N56K |
probably damaging |
Het |
| Tcte2 |
C |
A |
17: 13,948,270 (GRCm39) |
G3V |
probably damaging |
Het |
| Tent5b |
A |
G |
4: 133,213,393 (GRCm39) |
|
probably null |
Het |
| Tgfb3 |
T |
C |
12: 86,108,955 (GRCm39) |
D258G |
probably benign |
Het |
| Timeless |
G |
T |
10: 128,083,230 (GRCm39) |
G659V |
probably benign |
Het |
| Tor1b |
T |
C |
2: 30,846,589 (GRCm39) |
|
probably null |
Het |
| Trank1 |
T |
A |
9: 111,194,709 (GRCm39) |
L911Q |
probably damaging |
Het |
| Ttll2 |
C |
T |
17: 7,618,998 (GRCm39) |
V310I |
probably benign |
Het |
| Ttyh3 |
A |
T |
5: 140,615,221 (GRCm39) |
I389N |
probably damaging |
Het |
| Tut4 |
T |
C |
4: 108,406,417 (GRCm39) |
|
probably benign |
Het |
| Ube3b |
T |
C |
5: 114,536,488 (GRCm39) |
V216A |
probably benign |
Het |
| Vezf1 |
T |
A |
11: 87,965,520 (GRCm39) |
V254E |
probably damaging |
Het |
| Vmn1r122 |
T |
C |
7: 20,867,227 (GRCm39) |
E276G |
probably benign |
Het |
| Vmn1r167 |
T |
A |
7: 23,204,161 (GRCm39) |
N285I |
probably benign |
Het |
| Vmn2r45 |
T |
A |
7: 8,484,480 (GRCm39) |
I442F |
probably benign |
Het |
| Vwa8 |
C |
A |
14: 79,420,522 (GRCm39) |
A1741E |
probably damaging |
Het |
| Wdr20 |
T |
A |
12: 110,704,668 (GRCm39) |
V69E |
probably damaging |
Het |
| Xkr4 |
T |
G |
1: 3,287,074 (GRCm39) |
Q372P |
probably damaging |
Het |
|
| Other mutations in Tnn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00095:Tnn
|
APN |
1 |
159,953,021 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
IGL00433:Tnn
|
APN |
1 |
159,925,776 (GRCm39) |
splice site |
probably benign |
|
|
IGL00858:Tnn
|
APN |
1 |
159,915,962 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00939:Tnn
|
APN |
1 |
159,975,100 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01569:Tnn
|
APN |
1 |
159,948,124 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01591:Tnn
|
APN |
1 |
159,953,144 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01628:Tnn
|
APN |
1 |
159,975,172 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL01811:Tnn
|
APN |
1 |
159,934,705 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01813:Tnn
|
APN |
1 |
159,916,008 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02340:Tnn
|
APN |
1 |
159,972,775 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02488:Tnn
|
APN |
1 |
159,968,163 (GRCm39) |
missense |
probably benign |
0.21 |
|
IGL02535:Tnn
|
APN |
1 |
159,950,222 (GRCm39) |
splice site |
probably null |
|
|
IGL02563:Tnn
|
APN |
1 |
159,942,123 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02572:Tnn
|
APN |
1 |
159,913,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02740:Tnn
|
APN |
1 |
159,968,347 (GRCm39) |
splice site |
probably benign |
|
|
IGL02818:Tnn
|
APN |
1 |
159,943,848 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03284:Tnn
|
APN |
1 |
159,953,022 (GRCm39) |
missense |
probably benign |
0.01 |
|
1mM(1):Tnn
|
UTSW |
1 |
159,924,911 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4305001:Tnn
|
UTSW |
1 |
159,913,647 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R0023:Tnn
|
UTSW |
1 |
159,932,498 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0234:Tnn
|
UTSW |
1 |
159,916,036 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0316:Tnn
|
UTSW |
1 |
159,948,137 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0492:Tnn
|
UTSW |
1 |
159,948,327 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0547:Tnn
|
UTSW |
1 |
159,943,907 (GRCm39) |
intron |
probably benign |
|
|
R1067:Tnn
|
UTSW |
1 |
159,952,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1563:Tnn
|
UTSW |
1 |
159,952,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1565:Tnn
|
UTSW |
1 |
159,924,835 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1615:Tnn
|
UTSW |
1 |
159,945,978 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1637:Tnn
|
UTSW |
1 |
159,975,170 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1707:Tnn
|
UTSW |
1 |
159,972,714 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1758:Tnn
|
UTSW |
1 |
159,975,154 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R1797:Tnn
|
UTSW |
1 |
159,968,258 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1847:Tnn
|
UTSW |
1 |
159,943,752 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R1925:Tnn
|
UTSW |
1 |
159,924,799 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2182:Tnn
|
UTSW |
1 |
159,968,170 (GRCm39) |
splice site |
probably null |
|
|
R2196:Tnn
|
UTSW |
1 |
159,924,798 (GRCm39) |
nonsense |
probably null |
|
|
R2225:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2227:Tnn
|
UTSW |
1 |
159,975,035 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2286:Tnn
|
UTSW |
1 |
159,938,079 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2850:Tnn
|
UTSW |
1 |
159,966,857 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3110:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3111:Tnn
|
UTSW |
1 |
159,934,625 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3112:Tnn
|
UTSW |
1 |
159,943,856 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R3729:Tnn
|
UTSW |
1 |
159,973,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4183:Tnn
|
UTSW |
1 |
159,924,925 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4439:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4441:Tnn
|
UTSW |
1 |
159,943,650 (GRCm39) |
missense |
probably benign |
|
|
R4588:Tnn
|
UTSW |
1 |
159,972,681 (GRCm39) |
missense |
probably benign |
0.25 |
|
R4646:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4647:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4648:Tnn
|
UTSW |
1 |
159,973,612 (GRCm39) |
missense |
probably benign |
|
|
R4701:Tnn
|
UTSW |
1 |
159,975,338 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R4703:Tnn
|
UTSW |
1 |
159,943,815 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4737:Tnn
|
UTSW |
1 |
159,973,659 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4802:Tnn
|
UTSW |
1 |
159,972,603 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4977:Tnn
|
UTSW |
1 |
159,948,188 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5011:Tnn
|
UTSW |
1 |
159,953,949 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R5026:Tnn
|
UTSW |
1 |
159,973,707 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5027:Tnn
|
UTSW |
1 |
159,972,781 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5049:Tnn
|
UTSW |
1 |
159,968,308 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5119:Tnn
|
UTSW |
1 |
159,948,122 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5128:Tnn
|
UTSW |
1 |
159,950,464 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R5234:Tnn
|
UTSW |
1 |
159,972,569 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5398:Tnn
|
UTSW |
1 |
159,975,092 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5424:Tnn
|
UTSW |
1 |
159,950,272 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5452:Tnn
|
UTSW |
1 |
159,937,831 (GRCm39) |
missense |
probably benign |
0.13 |
|
R5466:Tnn
|
UTSW |
1 |
159,948,106 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R6022:Tnn
|
UTSW |
1 |
159,937,928 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6062:Tnn
|
UTSW |
1 |
159,925,848 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6086:Tnn
|
UTSW |
1 |
159,913,690 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6132:Tnn
|
UTSW |
1 |
159,973,641 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6324:Tnn
|
UTSW |
1 |
159,972,774 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6455:Tnn
|
UTSW |
1 |
159,942,289 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6563:Tnn
|
UTSW |
1 |
159,915,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6650:Tnn
|
UTSW |
1 |
159,942,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6806:Tnn
|
UTSW |
1 |
159,948,278 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6810:Tnn
|
UTSW |
1 |
159,932,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7157:Tnn
|
UTSW |
1 |
159,953,947 (GRCm39) |
nonsense |
probably null |
|
|
R7243:Tnn
|
UTSW |
1 |
159,934,687 (GRCm39) |
missense |
probably benign |
0.07 |
|
R7340:Tnn
|
UTSW |
1 |
159,973,592 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7472:Tnn
|
UTSW |
1 |
159,937,917 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7502:Tnn
|
UTSW |
1 |
159,937,929 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7527:Tnn
|
UTSW |
1 |
159,946,074 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R7608:Tnn
|
UTSW |
1 |
159,915,984 (GRCm39) |
nonsense |
probably null |
|
|
R7746:Tnn
|
UTSW |
1 |
159,942,255 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8096:Tnn
|
UTSW |
1 |
159,950,411 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8136:Tnn
|
UTSW |
1 |
159,934,630 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8191:Tnn
|
UTSW |
1 |
159,953,088 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8334:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8335:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8337:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8338:Tnn
|
UTSW |
1 |
159,946,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8427:Tnn
|
UTSW |
1 |
159,958,256 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8433:Tnn
|
UTSW |
1 |
159,924,790 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R8479:Tnn
|
UTSW |
1 |
159,950,397 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8505:Tnn
|
UTSW |
1 |
159,973,593 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8554:Tnn
|
UTSW |
1 |
159,937,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8717:Tnn
|
UTSW |
1 |
159,943,846 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R8850:Tnn
|
UTSW |
1 |
159,937,814 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8928:Tnn
|
UTSW |
1 |
159,953,099 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9209:Tnn
|
UTSW |
1 |
159,953,986 (GRCm39) |
missense |
probably benign |
0.02 |
|
X0019:Tnn
|
UTSW |
1 |
159,913,716 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Tnn
|
UTSW |
1 |
159,973,863 (GRCm39) |
missense |
probably benign |
|
|
Z1177:Tnn
|
UTSW |
1 |
159,954,097 (GRCm39) |
missense |
probably damaging |
0.98 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATTCTCCCGTTACCTGTGAGG -3'
(R):5'- GCCTGTCATGGTTGAAAGAGAG -3'
Sequencing Primer
(F):5'- CCGTTACCTGTGAGGGCCTTG -3'
(R):5'- CATGGTTGAAAGAGAGACTCCTTTG -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation