Incidental Mutation 'R4868:D430041D05Rik'
| ID |
376294 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
D430041D05Rik
|
| Ensembl Gene |
ENSMUSG00000068373 |
| Gene Name |
RIKEN cDNA D430041D05 gene |
| Synonyms |
G2 |
| MMRRC Submission |
042478-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.212)
|
| Stock # |
R4868 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
103973418-104241358 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 104085754 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Threonine to Alanine
at position 248
(T248A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000155023
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000089726]
[ENSMUST00000136156]
[ENSMUST00000141159]
[ENSMUST00000149466]
[ENSMUST00000230671]
|
| AlphaFold |
A0A2R8VKG2 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000089726
AA Change: T248A
PolyPhen 2
Score 0.613 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000106756
Gene: ENSMUSG00000068373
AA Change: T248A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
55 |
70 |
N/A |
INTRINSIC |
|
low complexity region
|
206 |
215 |
N/A |
INTRINSIC |
|
low complexity region
|
218 |
230 |
N/A |
INTRINSIC |
|
low complexity region
|
234 |
253 |
N/A |
INTRINSIC |
|
Pfam:DUF3827
|
498 |
1134 |
2.4e-282 |
PFAM |
|
low complexity region
|
1196 |
1217 |
N/A |
INTRINSIC |
|
low complexity region
|
1331 |
1351 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1372 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000136156
AA Change: T248A
PolyPhen 2
Score 0.732 (Sensitivity: 0.86; Specificity: 0.92)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000139015
|
| SMART Domains |
Protein: ENSMUSP00000124519
Gene: ENSMUSG00000068373
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
159 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
174 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000141159
AA Change: T133A
|
| SMART Domains |
Protein: ENSMUSP00000117041
Gene: ENSMUSG00000068373
AA Change: T133A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
55 |
70 |
N/A |
INTRINSIC |
|
low complexity region
|
91 |
100 |
N/A |
INTRINSIC |
|
low complexity region
|
103 |
115 |
N/A |
INTRINSIC |
|
low complexity region
|
119 |
138 |
N/A |
INTRINSIC |
|
Pfam:DUF3827
|
383 |
1020 |
8.2e-280 |
PFAM |
|
low complexity region
|
1082 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1217 |
1237 |
N/A |
INTRINSIC |
|
low complexity region
|
1246 |
1258 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000149165
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000149466
AA Change: T76A
PolyPhen 2
Score 0.659 (Sensitivity: 0.86; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000124980
Gene: ENSMUSG00000068373
AA Change: T76A
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
34 |
43 |
N/A |
INTRINSIC |
|
low complexity region
|
46 |
58 |
N/A |
INTRINSIC |
|
low complexity region
|
62 |
81 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000150450
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000151310
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000230671
AA Change: T932A
PolyPhen 2
Score 0.469 (Sensitivity: 0.89; Specificity: 0.90)
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 97.1%
- 20x: 94.7%
|
| Validation Efficiency |
99% (91/92) |
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 87 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4933405L10Rik |
A |
G |
8: 106,436,729 (GRCm39) |
*299W |
probably null |
Het |
| 4933412E24Rik |
G |
A |
15: 59,887,817 (GRCm39) |
L208F |
possibly damaging |
Het |
| Abca8b |
G |
A |
11: 109,865,338 (GRCm39) |
A373V |
probably benign |
Het |
| Actn3 |
A |
T |
19: 4,914,482 (GRCm39) |
W549R |
probably benign |
Het |
| Adamts4 |
C |
T |
1: 171,080,000 (GRCm39) |
|
probably benign |
Het |
| Adcy4 |
T |
C |
14: 56,011,179 (GRCm39) |
I615V |
probably benign |
Het |
| Akap1 |
A |
G |
11: 88,735,379 (GRCm39) |
S428P |
possibly damaging |
Het |
| Akap13 |
A |
T |
7: 75,393,252 (GRCm39) |
R2476W |
probably damaging |
Het |
| Alx3 |
A |
G |
3: 107,507,943 (GRCm39) |
S151G |
possibly damaging |
Het |
| Aoah |
T |
A |
13: 21,099,151 (GRCm39) |
Y243* |
probably null |
Het |
| Asap1 |
A |
G |
15: 63,966,030 (GRCm39) |
V1025A |
probably benign |
Het |
| Atp8b1 |
A |
T |
18: 64,684,937 (GRCm39) |
I728N |
probably damaging |
Het |
| Baz2b |
C |
A |
2: 59,755,226 (GRCm39) |
V1001L |
possibly damaging |
Het |
| Bmpr2 |
T |
A |
1: 59,909,615 (GRCm39) |
S1030T |
probably benign |
Het |
| Cacna2d3 |
A |
T |
14: 28,678,743 (GRCm39) |
|
probably null |
Het |
| Casp3 |
A |
T |
8: 47,087,314 (GRCm39) |
N87I |
probably benign |
Het |
| Ccdc171 |
T |
A |
4: 83,612,569 (GRCm39) |
L995Q |
probably damaging |
Het |
| Ccdc80 |
T |
A |
16: 44,924,776 (GRCm39) |
Y637N |
probably damaging |
Het |
| Ccr4 |
A |
G |
9: 114,321,901 (GRCm39) |
F55L |
probably benign |
Het |
| Cmah |
T |
A |
13: 24,648,247 (GRCm39) |
V494E |
probably damaging |
Het |
| Cnot6l |
A |
G |
5: 96,230,882 (GRCm39) |
Y362H |
probably damaging |
Het |
| Coq6 |
T |
C |
12: 84,417,726 (GRCm39) |
V222A |
probably damaging |
Het |
| Ctdspl2 |
C |
A |
2: 121,823,879 (GRCm39) |
T240N |
possibly damaging |
Het |
| Dctn6 |
A |
T |
8: 34,559,230 (GRCm39) |
|
probably benign |
Het |
| Dhx34 |
T |
C |
7: 15,933,727 (GRCm39) |
D955G |
probably benign |
Het |
| Dnaaf5 |
A |
G |
5: 139,155,941 (GRCm39) |
M541V |
probably benign |
Het |
| Dnah17 |
A |
T |
11: 117,999,038 (GRCm39) |
S912T |
probably benign |
Het |
| Dnah2 |
A |
T |
11: 69,354,474 (GRCm39) |
V2248E |
probably damaging |
Het |
| Dysf |
T |
C |
6: 84,156,675 (GRCm39) |
W1502R |
probably damaging |
Het |
| Dzip1 |
A |
T |
14: 119,114,626 (GRCm39) |
V843E |
probably damaging |
Het |
| Esp23 |
G |
T |
17: 39,384,915 (GRCm39) |
T27K |
probably benign |
Het |
| Esp3 |
A |
T |
17: 40,944,420 (GRCm39) |
M21L |
possibly damaging |
Het |
| Fam43b |
T |
A |
4: 138,123,108 (GRCm39) |
T71S |
probably benign |
Het |
| Fpgs |
G |
A |
2: 32,582,673 (GRCm39) |
R63C |
probably damaging |
Het |
| H2-M11 |
G |
T |
17: 36,859,811 (GRCm39) |
W268L |
probably damaging |
Het |
| Inpp5b |
T |
C |
4: 124,645,203 (GRCm39) |
S210P |
probably damaging |
Het |
| Itsn1 |
T |
A |
16: 91,582,205 (GRCm39) |
S51T |
probably damaging |
Het |
| Kctd2 |
G |
A |
11: 115,320,205 (GRCm39) |
V246I |
probably damaging |
Het |
| Krt75 |
C |
T |
15: 101,476,556 (GRCm39) |
G403E |
probably damaging |
Het |
| Lamp3 |
T |
A |
16: 19,520,040 (GRCm39) |
T48S |
probably benign |
Het |
| Lyzl4 |
C |
A |
9: 121,412,075 (GRCm39) |
V114L |
probably damaging |
Het |
| Maml3 |
C |
A |
3: 52,011,345 (GRCm39) |
E74* |
probably null |
Het |
| Map2k7 |
G |
A |
8: 4,297,751 (GRCm39) |
|
probably benign |
Het |
| Mapk8ip3 |
A |
G |
17: 25,120,389 (GRCm39) |
V883A |
probably benign |
Het |
| Mbtps1 |
C |
T |
8: 120,235,667 (GRCm39) |
V1004I |
probably benign |
Het |
| Metap1 |
G |
T |
3: 138,188,850 (GRCm39) |
H48Q |
probably damaging |
Het |
| Mical2 |
T |
A |
7: 111,917,831 (GRCm39) |
V396E |
probably damaging |
Het |
| Mks1 |
T |
A |
11: 87,744,549 (GRCm39) |
|
probably benign |
Het |
| Ndst1 |
T |
C |
18: 60,828,548 (GRCm39) |
T669A |
probably benign |
Het |
| Obox3 |
T |
C |
7: 15,361,235 (GRCm39) |
K10R |
probably damaging |
Het |
| Opn3 |
T |
C |
1: 175,491,127 (GRCm39) |
Y302C |
probably damaging |
Het |
| Or4f62 |
T |
A |
2: 111,986,916 (GRCm39) |
S207T |
probably damaging |
Het |
| Or6b6 |
C |
T |
7: 106,570,974 (GRCm39) |
M192I |
probably benign |
Het |
| Or9g8 |
T |
G |
2: 85,606,970 (GRCm39) |
V14G |
possibly damaging |
Het |
| Pdzph1 |
A |
T |
17: 59,281,751 (GRCm39) |
V177D |
probably benign |
Het |
| Pex5l |
T |
A |
3: 33,006,639 (GRCm39) |
I577F |
probably damaging |
Het |
| Pmpcb |
T |
A |
5: 21,953,851 (GRCm39) |
Y366* |
probably null |
Het |
| Prr14l |
A |
T |
5: 32,987,281 (GRCm39) |
M738K |
probably benign |
Het |
| Prx |
T |
C |
7: 27,217,004 (GRCm39) |
S641P |
probably benign |
Het |
| Ptchd3 |
A |
G |
11: 121,721,883 (GRCm39) |
Y252C |
possibly damaging |
Het |
| Reg3a |
A |
G |
6: 78,358,883 (GRCm39) |
E27G |
probably damaging |
Het |
| Ripor2 |
A |
G |
13: 24,878,124 (GRCm39) |
T300A |
possibly damaging |
Het |
| Sdf4 |
T |
A |
4: 156,093,642 (GRCm39) |
S259T |
probably damaging |
Het |
| Sike1 |
A |
G |
3: 102,904,730 (GRCm39) |
|
probably null |
Het |
| Sis |
T |
G |
3: 72,850,881 (GRCm39) |
I606L |
probably benign |
Het |
| Slc30a9 |
T |
C |
5: 67,482,026 (GRCm39) |
I94T |
probably benign |
Het |
| Slc5a4a |
T |
C |
10: 76,014,065 (GRCm39) |
I424T |
probably damaging |
Het |
| Spx |
C |
T |
6: 142,362,116 (GRCm39) |
R72* |
probably null |
Het |
| St7 |
C |
A |
6: 17,819,265 (GRCm39) |
N56K |
probably damaging |
Het |
| Tcte2 |
C |
A |
17: 13,948,270 (GRCm39) |
G3V |
probably damaging |
Het |
| Tent5b |
A |
G |
4: 133,213,393 (GRCm39) |
|
probably null |
Het |
| Tgfb3 |
T |
C |
12: 86,108,955 (GRCm39) |
D258G |
probably benign |
Het |
| Timeless |
G |
T |
10: 128,083,230 (GRCm39) |
G659V |
probably benign |
Het |
| Tnn |
T |
C |
1: 159,958,443 (GRCm39) |
R467G |
possibly damaging |
Het |
| Tor1b |
T |
C |
2: 30,846,589 (GRCm39) |
|
probably null |
Het |
| Trank1 |
T |
A |
9: 111,194,709 (GRCm39) |
L911Q |
probably damaging |
Het |
| Ttll2 |
C |
T |
17: 7,618,998 (GRCm39) |
V310I |
probably benign |
Het |
| Ttyh3 |
A |
T |
5: 140,615,221 (GRCm39) |
I389N |
probably damaging |
Het |
| Tut4 |
T |
C |
4: 108,406,417 (GRCm39) |
|
probably benign |
Het |
| Ube3b |
T |
C |
5: 114,536,488 (GRCm39) |
V216A |
probably benign |
Het |
| Vezf1 |
T |
A |
11: 87,965,520 (GRCm39) |
V254E |
probably damaging |
Het |
| Vmn1r122 |
T |
C |
7: 20,867,227 (GRCm39) |
E276G |
probably benign |
Het |
| Vmn1r167 |
T |
A |
7: 23,204,161 (GRCm39) |
N285I |
probably benign |
Het |
| Vmn2r45 |
T |
A |
7: 8,484,480 (GRCm39) |
I442F |
probably benign |
Het |
| Vwa8 |
C |
A |
14: 79,420,522 (GRCm39) |
A1741E |
probably damaging |
Het |
| Wdr20 |
T |
A |
12: 110,704,668 (GRCm39) |
V69E |
probably damaging |
Het |
| Xkr4 |
T |
G |
1: 3,287,074 (GRCm39) |
Q372P |
probably damaging |
Het |
|
| Other mutations in D430041D05Rik |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00838:D430041D05Rik
|
APN |
2 |
104,031,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01114:D430041D05Rik
|
APN |
2 |
104,088,511 (GRCm39) |
nonsense |
probably null |
|
|
IGL01669:D430041D05Rik
|
APN |
2 |
104,085,306 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02015:D430041D05Rik
|
APN |
2 |
104,060,749 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02037:D430041D05Rik
|
APN |
2 |
104,038,559 (GRCm39) |
splice site |
probably benign |
|
|
IGL02268:D430041D05Rik
|
APN |
2 |
104,071,500 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02294:D430041D05Rik
|
APN |
2 |
104,085,351 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL02457:D430041D05Rik
|
APN |
2 |
104,079,690 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02601:D430041D05Rik
|
APN |
2 |
104,060,631 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02647:D430041D05Rik
|
APN |
2 |
104,078,611 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02679:D430041D05Rik
|
APN |
2 |
104,060,650 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
IGL02926:D430041D05Rik
|
APN |
2 |
104,044,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03171:D430041D05Rik
|
APN |
2 |
104,071,508 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL03178:D430041D05Rik
|
APN |
2 |
104,051,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03371:D430041D05Rik
|
APN |
2 |
104,078,719 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0027:D430041D05Rik
|
UTSW |
2 |
104,085,389 (GRCm39) |
missense |
probably benign |
|
|
R0064:D430041D05Rik
|
UTSW |
2 |
104,079,502 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0135:D430041D05Rik
|
UTSW |
2 |
104,085,379 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R0227:D430041D05Rik
|
UTSW |
2 |
104,035,545 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R0265:D430041D05Rik
|
UTSW |
2 |
103,998,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0268:D430041D05Rik
|
UTSW |
2 |
103,998,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0282:D430041D05Rik
|
UTSW |
2 |
104,031,589 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0366:D430041D05Rik
|
UTSW |
2 |
104,085,685 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0402:D430041D05Rik
|
UTSW |
2 |
103,998,509 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0436:D430041D05Rik
|
UTSW |
2 |
103,998,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0441:D430041D05Rik
|
UTSW |
2 |
103,998,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0540:D430041D05Rik
|
UTSW |
2 |
104,063,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0607:D430041D05Rik
|
UTSW |
2 |
104,063,790 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0613:D430041D05Rik
|
UTSW |
2 |
103,998,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0626:D430041D05Rik
|
UTSW |
2 |
103,998,295 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0747:D430041D05Rik
|
UTSW |
2 |
104,060,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0864:D430041D05Rik
|
UTSW |
2 |
104,060,773 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R0980:D430041D05Rik
|
UTSW |
2 |
104,079,690 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1014:D430041D05Rik
|
UTSW |
2 |
104,088,674 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1254:D430041D05Rik
|
UTSW |
2 |
104,031,648 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1364:D430041D05Rik
|
UTSW |
2 |
103,985,363 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1456:D430041D05Rik
|
UTSW |
2 |
104,038,428 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1574:D430041D05Rik
|
UTSW |
2 |
104,051,553 (GRCm39) |
small deletion |
probably benign |
|
|
R1604:D430041D05Rik
|
UTSW |
2 |
104,035,487 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1605:D430041D05Rik
|
UTSW |
2 |
104,085,915 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1623:D430041D05Rik
|
UTSW |
2 |
103,983,308 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1634:D430041D05Rik
|
UTSW |
2 |
104,051,556 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1834:D430041D05Rik
|
UTSW |
2 |
103,998,446 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1885:D430041D05Rik
|
UTSW |
2 |
104,060,800 (GRCm39) |
missense |
probably benign |
0.39 |
|
R2080:D430041D05Rik
|
UTSW |
2 |
103,987,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2101:D430041D05Rik
|
UTSW |
2 |
103,979,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2240:D430041D05Rik
|
UTSW |
2 |
103,987,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2923:D430041D05Rik
|
UTSW |
2 |
104,085,660 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3751:D430041D05Rik
|
UTSW |
2 |
104,085,403 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R3862:D430041D05Rik
|
UTSW |
2 |
104,044,522 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R3863:D430041D05Rik
|
UTSW |
2 |
104,044,522 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R3864:D430041D05Rik
|
UTSW |
2 |
104,044,522 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R3949:D430041D05Rik
|
UTSW |
2 |
104,087,713 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4493:D430041D05Rik
|
UTSW |
2 |
104,086,684 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4526:D430041D05Rik
|
UTSW |
2 |
104,022,778 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4592:D430041D05Rik
|
UTSW |
2 |
104,063,824 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R4598:D430041D05Rik
|
UTSW |
2 |
104,038,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4599:D430041D05Rik
|
UTSW |
2 |
104,038,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4647:D430041D05Rik
|
UTSW |
2 |
104,088,788 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4765:D430041D05Rik
|
UTSW |
2 |
104,044,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4808:D430041D05Rik
|
UTSW |
2 |
104,031,455 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4982:D430041D05Rik
|
UTSW |
2 |
104,085,732 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5144:D430041D05Rik
|
UTSW |
2 |
104,088,847 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5255:D430041D05Rik
|
UTSW |
2 |
104,086,945 (GRCm39) |
missense |
probably benign |
0.26 |
|
R5356:D430041D05Rik
|
UTSW |
2 |
104,085,754 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5368:D430041D05Rik
|
UTSW |
2 |
104,078,629 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5963:D430041D05Rik
|
UTSW |
2 |
104,078,630 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5993:D430041D05Rik
|
UTSW |
2 |
103,998,412 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6122:D430041D05Rik
|
UTSW |
2 |
104,086,637 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6410:D430041D05Rik
|
UTSW |
2 |
103,998,548 (GRCm39) |
splice site |
probably null |
|
|
R6804:D430041D05Rik
|
UTSW |
2 |
103,979,371 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6850:D430041D05Rik
|
UTSW |
2 |
104,031,604 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6853:D430041D05Rik
|
UTSW |
2 |
104,071,500 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7034:D430041D05Rik
|
UTSW |
2 |
104,022,883 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7146:D430041D05Rik
|
UTSW |
2 |
104,088,698 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7250:D430041D05Rik
|
UTSW |
2 |
104,086,961 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7251:D430041D05Rik
|
UTSW |
2 |
104,051,511 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7313:D430041D05Rik
|
UTSW |
2 |
104,085,910 (GRCm39) |
missense |
probably benign |
|
|
R7359:D430041D05Rik
|
UTSW |
2 |
104,044,482 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7361:D430041D05Rik
|
UTSW |
2 |
104,085,363 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7436:D430041D05Rik
|
UTSW |
2 |
104,087,447 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7472:D430041D05Rik
|
UTSW |
2 |
104,240,484 (GRCm39) |
missense |
unknown |
|
|
R7492:D430041D05Rik
|
UTSW |
2 |
104,031,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7631:D430041D05Rik
|
UTSW |
2 |
103,979,363 (GRCm39) |
nonsense |
probably null |
|
|
R7672:D430041D05Rik
|
UTSW |
2 |
104,071,581 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7721:D430041D05Rik
|
UTSW |
2 |
104,088,874 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7754:D430041D05Rik
|
UTSW |
2 |
104,087,504 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7882:D430041D05Rik
|
UTSW |
2 |
104,087,974 (GRCm39) |
nonsense |
probably null |
|
|
R7896:D430041D05Rik
|
UTSW |
2 |
104,088,385 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7986:D430041D05Rik
|
UTSW |
2 |
104,087,096 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8005:D430041D05Rik
|
UTSW |
2 |
104,088,599 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
R8016:D430041D05Rik
|
UTSW |
2 |
104,022,864 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8054:D430041D05Rik
|
UTSW |
2 |
103,985,390 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8058:D430041D05Rik
|
UTSW |
2 |
103,979,128 (GRCm39) |
makesense |
probably null |
|
|
R8100:D430041D05Rik
|
UTSW |
2 |
104,087,287 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8461:D430041D05Rik
|
UTSW |
2 |
103,998,280 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8695:D430041D05Rik
|
UTSW |
2 |
104,085,299 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8885:D430041D05Rik
|
UTSW |
2 |
104,071,538 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9007:D430041D05Rik
|
UTSW |
2 |
104,087,930 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9009:D430041D05Rik
|
UTSW |
2 |
104,240,521 (GRCm39) |
start gained |
probably benign |
|
|
R9335:D430041D05Rik
|
UTSW |
2 |
104,078,674 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9348:D430041D05Rik
|
UTSW |
2 |
104,088,337 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9384:D430041D05Rik
|
UTSW |
2 |
104,087,920 (GRCm39) |
missense |
probably benign |
|
|
R9483:D430041D05Rik
|
UTSW |
2 |
104,087,563 (GRCm39) |
missense |
probably benign |
0.44 |
|
R9489:D430041D05Rik
|
UTSW |
2 |
104,087,189 (GRCm39) |
missense |
probably benign |
0.20 |
|
R9605:D430041D05Rik
|
UTSW |
2 |
104,087,189 (GRCm39) |
missense |
probably benign |
0.20 |
|
R9613:D430041D05Rik
|
UTSW |
2 |
104,060,737 (GRCm39) |
missense |
probably benign |
0.09 |
|
R9698:D430041D05Rik
|
UTSW |
2 |
103,985,396 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0024:D430041D05Rik
|
UTSW |
2 |
104,022,911 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
Z1176:D430041D05Rik
|
UTSW |
2 |
104,087,201 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:D430041D05Rik
|
UTSW |
2 |
103,985,280 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:D430041D05Rik
|
UTSW |
2 |
104,071,536 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCAGTGTGCATGGCTTGTG -3'
(R):5'- GGTCCAGTGACAAACTTTTCC -3'
Sequencing Primer
(F):5'- TTGTGGACAACAGGCCG -3'
(R):5'- GGTCCAGTGACAAACTTTTCCTTTTC -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation