Incidental Mutation 'R4871:Myh7b'
| ID |
376557 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Myh7b
|
| Ensembl Gene |
ENSMUSG00000074652 |
| Gene Name |
myosin, heavy chain 7B, cardiac muscle, beta |
| Synonyms |
Myh14 |
| MMRRC Submission |
042481-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4871 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
155453132-155476227 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 155455420 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Methionine to Lysine
at position 89
(M89K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000090672
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000092995]
|
| AlphaFold |
A2AQP0 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000092995
AA Change: M89K
PolyPhen 2
Score 0.178 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000090672
Gene: ENSMUSG00000074652
AA Change: M89K
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Myosin_N
|
32 |
72 |
4.7e-14 |
PFAM |
|
MYSc
|
78 |
786 |
N/A |
SMART |
|
IQ
|
787 |
809 |
2.6e0 |
SMART |
|
Pfam:Myosin_tail_1
|
850 |
1931 |
5.5e-149 |
PFAM |
|
| Meta Mutation Damage Score |
0.2684 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.1%
|
| Validation Efficiency |
93% (99/107) |
| MGI Phenotype |
FUNCTION: This gene encodes a myosin heavy chain. The encoded protein forms a hexamer comprised of two heavy chains, two alkali light chains, and two regulatory light chain components. This complex functions in muscle contraction. [provided by RefSeq, Jun 2013]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adcyap1r1 |
A |
G |
6: 55,457,078 (GRCm39) |
T270A |
probably null |
Het |
| Adgrv1 |
A |
T |
13: 81,681,241 (GRCm39) |
|
probably benign |
Het |
| Aldh1b1 |
A |
T |
4: 45,803,383 (GRCm39) |
D307V |
probably benign |
Het |
| Aldh3a2 |
A |
T |
11: 61,153,065 (GRCm39) |
C220* |
probably null |
Het |
| Ank2 |
T |
C |
3: 126,753,444 (GRCm39) |
Y279C |
probably damaging |
Het |
| Anks1 |
T |
C |
17: 28,210,351 (GRCm39) |
Y444H |
probably benign |
Het |
| Asph |
G |
T |
4: 9,531,968 (GRCm39) |
T383K |
probably benign |
Het |
| Asphd1 |
G |
T |
7: 126,547,747 (GRCm39) |
S185R |
possibly damaging |
Het |
| Bcl2a1d |
T |
A |
9: 88,613,748 (GRCm39) |
I9F |
probably damaging |
Het |
| Bcl2l11 |
T |
C |
2: 127,970,961 (GRCm39) |
|
probably benign |
Het |
| C2cd3 |
T |
G |
7: 100,062,581 (GRCm39) |
S656A |
possibly damaging |
Het |
| Cd5l |
T |
C |
3: 87,274,929 (GRCm39) |
V156A |
probably damaging |
Het |
| Cdh8 |
G |
C |
8: 99,757,536 (GRCm39) |
N687K |
probably damaging |
Het |
| Cdk19 |
A |
G |
10: 40,352,232 (GRCm39) |
D338G |
probably benign |
Het |
| Cenpf |
A |
G |
1: 189,390,728 (GRCm39) |
C1035R |
probably damaging |
Het |
| Cep290 |
A |
G |
10: 100,384,776 (GRCm39) |
R1845G |
probably benign |
Het |
| Cep295nl |
G |
T |
11: 118,224,650 (GRCm39) |
Q65K |
probably damaging |
Het |
| Ciz1 |
T |
C |
2: 32,262,300 (GRCm39) |
|
probably benign |
Het |
| Clasrp |
T |
C |
7: 19,324,173 (GRCm39) |
D234G |
possibly damaging |
Het |
| Dctd |
C |
T |
8: 48,590,449 (GRCm39) |
|
probably benign |
Het |
| Ddr2 |
A |
G |
1: 169,832,340 (GRCm39) |
V150A |
probably benign |
Het |
| Dennd10 |
A |
G |
19: 60,819,252 (GRCm39) |
E120G |
probably damaging |
Het |
| Dnah7b |
T |
C |
1: 46,120,604 (GRCm39) |
S74P |
probably benign |
Het |
| Dnttip2 |
C |
A |
3: 122,078,750 (GRCm39) |
A743E |
probably damaging |
Het |
| Dysf |
A |
T |
6: 84,044,005 (GRCm39) |
Q281L |
possibly damaging |
Het |
| Ece2 |
A |
G |
16: 20,462,905 (GRCm39) |
E610G |
probably damaging |
Het |
| Edem3 |
T |
G |
1: 151,679,982 (GRCm39) |
|
probably null |
Het |
| Ext1 |
G |
T |
15: 52,955,773 (GRCm39) |
N441K |
probably benign |
Het |
| Fam118a |
A |
G |
15: 84,942,969 (GRCm39) |
R333G |
probably damaging |
Het |
| Fat4 |
C |
T |
3: 38,945,754 (GRCm39) |
T1549I |
probably damaging |
Het |
| Fbxo4 |
A |
G |
15: 4,005,394 (GRCm39) |
V162A |
probably damaging |
Het |
| Fgd2 |
A |
G |
17: 29,592,223 (GRCm39) |
H385R |
possibly damaging |
Het |
| Garnl3 |
A |
T |
2: 32,977,100 (GRCm39) |
M1K |
probably null |
Het |
| Gm37267 |
T |
G |
1: 180,338,083 (GRCm39) |
|
noncoding transcript |
Het |
| Gpbar1 |
C |
T |
1: 74,318,702 (GRCm39) |
A315V |
probably damaging |
Het |
| Grm2 |
T |
C |
9: 106,524,844 (GRCm39) |
I624V |
probably benign |
Het |
| Hmcn1 |
T |
C |
1: 150,468,836 (GRCm39) |
I5042V |
probably benign |
Het |
| Hnf4g |
T |
C |
3: 3,716,448 (GRCm39) |
Y291H |
possibly damaging |
Het |
| Ighm |
A |
G |
12: 113,385,241 (GRCm39) |
S240P |
unknown |
Het |
| Igkv4-91 |
A |
G |
6: 68,745,604 (GRCm39) |
I98T |
probably damaging |
Het |
| Krt72 |
T |
C |
15: 101,694,469 (GRCm39) |
N142S |
probably damaging |
Het |
| Kynu |
T |
A |
2: 43,569,830 (GRCm39) |
Y371N |
possibly damaging |
Het |
| Ly9 |
G |
T |
1: 171,434,898 (GRCm39) |
|
probably benign |
Het |
| Man1a2 |
C |
A |
3: 100,524,372 (GRCm39) |
V359F |
probably damaging |
Het |
| Mast1 |
T |
C |
8: 85,647,287 (GRCm39) |
I623M |
probably damaging |
Het |
| Mb |
A |
G |
15: 76,906,687 (GRCm39) |
|
probably null |
Het |
| Mcm4 |
A |
C |
16: 15,452,374 (GRCm39) |
L113* |
probably null |
Het |
| Mcub |
C |
T |
3: 129,710,685 (GRCm39) |
W249* |
probably null |
Het |
| Mme |
T |
A |
3: 63,247,453 (GRCm39) |
V246E |
probably benign |
Het |
| Mplkipl1 |
C |
T |
19: 61,164,364 (GRCm39) |
G24R |
unknown |
Het |
| Mrpl38 |
A |
G |
11: 116,025,098 (GRCm39) |
Y232H |
probably damaging |
Het |
| Notch4 |
A |
G |
17: 34,796,536 (GRCm39) |
S892G |
possibly damaging |
Het |
| Nt5dc3 |
A |
G |
10: 86,652,941 (GRCm39) |
Y245C |
probably damaging |
Het |
| Ntn1 |
CCTTCTTCT |
CCTTCT |
11: 68,103,852 (GRCm39) |
|
probably benign |
Het |
| Or12d12 |
T |
A |
17: 37,611,095 (GRCm39) |
T73S |
probably benign |
Het |
| Or12d14-ps1 |
A |
T |
17: 37,673,337 (GRCm39) |
I107L |
probably benign |
Het |
| Or14a259 |
A |
T |
7: 86,012,692 (GRCm39) |
N284K |
probably damaging |
Het |
| Or5m12 |
T |
A |
2: 85,734,715 (GRCm39) |
I228F |
probably benign |
Het |
| Or8b36 |
G |
T |
9: 37,937,822 (GRCm39) |
C240F |
probably damaging |
Het |
| Or8k28 |
A |
T |
2: 86,286,153 (GRCm39) |
I154N |
possibly damaging |
Het |
| Palld |
A |
T |
8: 62,002,815 (GRCm39) |
|
probably benign |
Het |
| Pcdhga10 |
T |
C |
18: 37,881,253 (GRCm39) |
V338A |
probably damaging |
Het |
| Pcdhga11 |
A |
G |
18: 37,890,459 (GRCm39) |
Y489C |
probably damaging |
Het |
| Pgm2 |
T |
C |
5: 64,261,237 (GRCm39) |
Y244H |
probably benign |
Het |
| Phactr4 |
A |
T |
4: 132,105,759 (GRCm39) |
S102R |
probably damaging |
Het |
| Plekha5 |
A |
G |
6: 140,471,636 (GRCm39) |
Y20C |
probably damaging |
Het |
| Rdh19 |
A |
G |
10: 127,696,013 (GRCm39) |
D255G |
probably benign |
Het |
| Rgs3 |
T |
C |
4: 62,549,532 (GRCm39) |
V438A |
probably benign |
Het |
| Rnf186 |
A |
G |
4: 138,695,254 (GRCm39) |
T265A |
probably benign |
Het |
| Ror1 |
T |
C |
4: 100,283,195 (GRCm39) |
F420S |
probably benign |
Het |
| Rtkn2 |
A |
G |
10: 67,841,463 (GRCm39) |
K204E |
probably damaging |
Het |
| Rundc1 |
A |
G |
11: 101,324,874 (GRCm39) |
T527A |
probably benign |
Het |
| Samd4 |
T |
C |
14: 47,303,920 (GRCm39) |
S301P |
probably damaging |
Het |
| Scaf1 |
G |
A |
7: 44,655,303 (GRCm39) |
|
probably benign |
Het |
| Srgap2 |
A |
G |
1: 131,217,210 (GRCm39) |
V1034A |
probably benign |
Het |
| Stab2 |
T |
C |
10: 86,778,099 (GRCm39) |
D743G |
probably damaging |
Het |
| Stim1 |
A |
T |
7: 102,003,779 (GRCm39) |
I71F |
probably damaging |
Het |
| Stk17b |
T |
C |
1: 53,796,693 (GRCm39) |
D358G |
probably benign |
Het |
| Sun2 |
A |
G |
15: 79,611,765 (GRCm39) |
Y551H |
probably damaging |
Het |
| Tas2r110 |
A |
T |
6: 132,845,091 (GRCm39) |
T41S |
probably benign |
Het |
| Tead3 |
T |
A |
17: 28,552,589 (GRCm39) |
E268V |
probably damaging |
Het |
| Tead3 |
A |
G |
17: 28,553,962 (GRCm39) |
S131P |
probably benign |
Het |
| Tepsin |
A |
T |
11: 119,982,351 (GRCm39) |
M505K |
possibly damaging |
Het |
| Trbv28 |
A |
G |
6: 41,248,668 (GRCm39) |
Y66C |
possibly damaging |
Het |
| Ttc6 |
A |
G |
12: 57,749,142 (GRCm39) |
Q1358R |
probably damaging |
Het |
| Ttll2 |
C |
T |
17: 7,618,998 (GRCm39) |
V310I |
probably benign |
Het |
| Uaca |
T |
C |
9: 60,753,283 (GRCm39) |
V76A |
probably damaging |
Het |
| Vwf |
A |
T |
6: 125,663,425 (GRCm39) |
T2789S |
probably benign |
Het |
| Yipf4 |
T |
C |
17: 74,801,089 (GRCm39) |
F136L |
probably benign |
Het |
| Zdhhc1 |
CGGGGG |
CGGGGGG |
8: 106,210,376 (GRCm39) |
|
probably null |
Het |
| Zfp804b |
A |
T |
5: 6,926,479 (GRCm39) |
D51E |
probably damaging |
Het |
| Zfyve9 |
C |
T |
4: 108,538,183 (GRCm39) |
G969R |
probably damaging |
Het |
|
| Other mutations in Myh7b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00931:Myh7b
|
APN |
2 |
155,472,212 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01604:Myh7b
|
APN |
2 |
155,474,327 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02179:Myh7b
|
APN |
2 |
155,456,411 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02729:Myh7b
|
APN |
2 |
155,467,609 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02804:Myh7b
|
APN |
2 |
155,467,643 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02851:Myh7b
|
APN |
2 |
155,470,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02956:Myh7b
|
APN |
2 |
155,467,874 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
IGL02956:Myh7b
|
APN |
2 |
155,474,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02992:Myh7b
|
APN |
2 |
155,463,330 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL03060:Myh7b
|
APN |
2 |
155,474,671 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03061:Myh7b
|
APN |
2 |
155,462,031 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03226:Myh7b
|
APN |
2 |
155,462,403 (GRCm39) |
nonsense |
probably null |
|
|
IGL03246:Myh7b
|
APN |
2 |
155,459,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03382:Myh7b
|
APN |
2 |
155,465,399 (GRCm39) |
missense |
probably damaging |
1.00 |
|
euclidian
|
UTSW |
2 |
155,475,319 (GRCm39) |
missense |
probably benign |
0.32 |
|
imaginary
|
UTSW |
2 |
155,474,175 (GRCm39) |
missense |
probably benign |
0.36 |
|
Irrational
|
UTSW |
2 |
155,472,592 (GRCm39) |
unclassified |
probably benign |
|
|
Muscoli
|
UTSW |
2 |
155,462,038 (GRCm39) |
nonsense |
probably null |
|
|
R0015:Myh7b
|
UTSW |
2 |
155,464,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0015:Myh7b
|
UTSW |
2 |
155,464,206 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Myh7b
|
UTSW |
2 |
155,453,594 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0309:Myh7b
|
UTSW |
2 |
155,472,592 (GRCm39) |
unclassified |
probably benign |
|
|
R0567:Myh7b
|
UTSW |
2 |
155,468,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0619:Myh7b
|
UTSW |
2 |
155,453,642 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0927:Myh7b
|
UTSW |
2 |
155,462,040 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0973:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R0973:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R0974:Myh7b
|
UTSW |
2 |
155,462,347 (GRCm39) |
missense |
probably benign |
|
|
R1137:Myh7b
|
UTSW |
2 |
155,464,634 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1261:Myh7b
|
UTSW |
2 |
155,463,003 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1268:Myh7b
|
UTSW |
2 |
155,455,966 (GRCm39) |
nonsense |
probably null |
|
|
R1537:Myh7b
|
UTSW |
2 |
155,473,707 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1632:Myh7b
|
UTSW |
2 |
155,462,445 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1694:Myh7b
|
UTSW |
2 |
155,455,113 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1697:Myh7b
|
UTSW |
2 |
155,462,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1730:Myh7b
|
UTSW |
2 |
155,467,592 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R1762:Myh7b
|
UTSW |
2 |
155,472,778 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1783:Myh7b
|
UTSW |
2 |
155,467,592 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R2105:Myh7b
|
UTSW |
2 |
155,471,377 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2140:Myh7b
|
UTSW |
2 |
155,462,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2971:Myh7b
|
UTSW |
2 |
155,474,175 (GRCm39) |
missense |
probably benign |
0.36 |
|
R3838:Myh7b
|
UTSW |
2 |
155,474,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4074:Myh7b
|
UTSW |
2 |
155,460,678 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4191:Myh7b
|
UTSW |
2 |
155,475,319 (GRCm39) |
missense |
probably benign |
0.32 |
|
R4689:Myh7b
|
UTSW |
2 |
155,472,434 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R4695:Myh7b
|
UTSW |
2 |
155,456,097 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4697:Myh7b
|
UTSW |
2 |
155,471,242 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4771:Myh7b
|
UTSW |
2 |
155,468,314 (GRCm39) |
nonsense |
probably null |
|
|
R4794:Myh7b
|
UTSW |
2 |
155,465,186 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4842:Myh7b
|
UTSW |
2 |
155,475,909 (GRCm39) |
missense |
probably benign |
0.45 |
|
R5022:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5023:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5025:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5050:Myh7b
|
UTSW |
2 |
155,473,670 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5055:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5056:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5161:Myh7b
|
UTSW |
2 |
155,474,293 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R5284:Myh7b
|
UTSW |
2 |
155,474,234 (GRCm39) |
missense |
probably benign |
|
|
R5422:Myh7b
|
UTSW |
2 |
155,472,954 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5505:Myh7b
|
UTSW |
2 |
155,474,592 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5946:Myh7b
|
UTSW |
2 |
155,463,315 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6089:Myh7b
|
UTSW |
2 |
155,464,409 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6103:Myh7b
|
UTSW |
2 |
155,460,663 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Myh7b
|
UTSW |
2 |
155,473,719 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R6292:Myh7b
|
UTSW |
2 |
155,474,316 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6350:Myh7b
|
UTSW |
2 |
155,470,680 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6484:Myh7b
|
UTSW |
2 |
155,470,563 (GRCm39) |
missense |
probably benign |
0.05 |
|
R6760:Myh7b
|
UTSW |
2 |
155,462,038 (GRCm39) |
nonsense |
probably null |
|
|
R6896:Myh7b
|
UTSW |
2 |
155,464,488 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6945:Myh7b
|
UTSW |
2 |
155,464,152 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7020:Myh7b
|
UTSW |
2 |
155,473,671 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7052:Myh7b
|
UTSW |
2 |
155,456,053 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7102:Myh7b
|
UTSW |
2 |
155,464,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7248:Myh7b
|
UTSW |
2 |
155,464,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7303:Myh7b
|
UTSW |
2 |
155,460,660 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7360:Myh7b
|
UTSW |
2 |
155,474,460 (GRCm39) |
missense |
probably benign |
0.38 |
|
R7652:Myh7b
|
UTSW |
2 |
155,474,156 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7678:Myh7b
|
UTSW |
2 |
155,459,698 (GRCm39) |
splice site |
probably null |
|
|
R7703:Myh7b
|
UTSW |
2 |
155,462,356 (GRCm39) |
missense |
probably null |
1.00 |
|
R7711:Myh7b
|
UTSW |
2 |
155,462,323 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7923:Myh7b
|
UTSW |
2 |
155,467,886 (GRCm39) |
missense |
probably benign |
|
|
R7967:Myh7b
|
UTSW |
2 |
155,456,119 (GRCm39) |
splice site |
probably null |
|
|
R8045:Myh7b
|
UTSW |
2 |
155,455,101 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8176:Myh7b
|
UTSW |
2 |
155,467,886 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8272:Myh7b
|
UTSW |
2 |
155,474,824 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8560:Myh7b
|
UTSW |
2 |
155,465,124 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R8706:Myh7b
|
UTSW |
2 |
155,453,669 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8824:Myh7b
|
UTSW |
2 |
155,472,301 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8832:Myh7b
|
UTSW |
2 |
155,475,182 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9079:Myh7b
|
UTSW |
2 |
155,465,174 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9151:Myh7b
|
UTSW |
2 |
155,474,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Myh7b
|
UTSW |
2 |
155,463,253 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9332:Myh7b
|
UTSW |
2 |
155,470,722 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9357:Myh7b
|
UTSW |
2 |
155,463,268 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9388:Myh7b
|
UTSW |
2 |
155,472,983 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9583:Myh7b
|
UTSW |
2 |
155,459,641 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Myh7b
|
UTSW |
2 |
155,455,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9738:Myh7b
|
UTSW |
2 |
155,455,963 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0013:Myh7b
|
UTSW |
2 |
155,473,089 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ATATTAGCCCCTCTGACCCTGG -3'
(R):5'- AGAGCCCTCTTCTAGCCTAG -3'
Sequencing Primer
(F):5'- CAGCTGGATCCACAGAGTG -3'
(R):5'- TAGCCTAGCCACTCCTAGTCACG -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation