Incidental Mutation 'R4876:Dennd4a'
| ID |
376886 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dennd4a
|
| Ensembl Gene |
ENSMUSG00000053641 |
| Gene Name |
DENN domain containing 4A |
| Synonyms |
F730015K02Rik |
| MMRRC Submission |
042485-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.489)
|
| Stock # |
R4876 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
64718622-64826949 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 64803872 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 1070
(N1070K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000037915
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000038890]
|
| AlphaFold |
E9Q8V6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000038890
AA Change: N1070K
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| SMART Domains |
Protein: ENSMUSP00000037915
Gene: ENSMUSG00000053641
AA Change: N1070K
| Domain | Start | End | E-Value | Type |
|---|
|
internal_repeat_1
|
45 |
93 |
3.26e-5 |
PROSPERO |
|
uDENN
|
169 |
276 |
1.71e-28 |
SMART |
|
DENN
|
309 |
493 |
2.4e-73 |
SMART |
|
dDENN
|
559 |
633 |
4.15e-27 |
SMART |
|
low complexity region
|
724 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
936 |
950 |
N/A |
INTRINSIC |
|
low complexity region
|
1176 |
1191 |
N/A |
INTRINSIC |
|
low complexity region
|
1249 |
1262 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1417 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000216098
|
| Meta Mutation Damage Score |
0.0618 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.4%
- 20x: 92.5%
|
| Validation Efficiency |
99% (97/98) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a DENN domain-containing protein that may function as a guanine nucleotide exchange factor that specifically activates ras-related protein Rab-10. This protein also contains a interferon stimulated response element-binding domain and may be involved in regulating the v-myc avian myelocytomatosis viral (MYC) oncogene. Alternate splicing results in multiple transcript variants. A pseudogene of this gene is found on chromosome 8. [provided by RefSeq, Mar 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930562C15Rik |
T |
C |
16: 4,667,536 (GRCm39) |
F309S |
unknown |
Het |
| A630001G21Rik |
C |
T |
1: 85,646,761 (GRCm39) |
V167M |
probably damaging |
Het |
| Anks6 |
C |
T |
4: 47,030,795 (GRCm39) |
G601S |
probably damaging |
Het |
| Ano4 |
A |
G |
10: 88,948,697 (GRCm39) |
F138L |
probably damaging |
Het |
| Aoc1 |
T |
C |
6: 48,883,681 (GRCm39) |
V519A |
possibly damaging |
Het |
| Arhgef37 |
A |
T |
18: 61,631,310 (GRCm39) |
Y558* |
probably null |
Het |
| Atxn3 |
T |
A |
12: 101,914,638 (GRCm39) |
S29C |
probably damaging |
Het |
| Bbs2 |
T |
C |
8: 94,796,788 (GRCm39) |
|
probably benign |
Het |
| Bicral |
A |
T |
17: 47,136,502 (GRCm39) |
I236N |
probably damaging |
Het |
| Cabcoco1 |
A |
G |
10: 68,377,599 (GRCm39) |
V30A |
probably benign |
Het |
| Cap2 |
A |
G |
13: 46,684,497 (GRCm39) |
M1V |
probably null |
Het |
| Ccdc153 |
T |
C |
9: 44,152,305 (GRCm39) |
M1T |
probably null |
Het |
| Ccnf |
A |
T |
17: 24,449,311 (GRCm39) |
V489D |
probably damaging |
Het |
| Cdin1 |
A |
C |
2: 115,500,539 (GRCm39) |
H159P |
probably damaging |
Het |
| Cntnap3 |
T |
C |
13: 64,935,520 (GRCm39) |
T448A |
probably benign |
Het |
| Cpa4 |
G |
A |
6: 30,590,814 (GRCm39) |
D371N |
probably benign |
Het |
| Csl |
T |
A |
10: 99,594,402 (GRCm39) |
Y221F |
possibly damaging |
Het |
| Dalrd3 |
T |
C |
9: 108,448,635 (GRCm39) |
|
probably benign |
Het |
| Dipk2a |
C |
T |
9: 94,419,630 (GRCm39) |
R100H |
probably damaging |
Het |
| Dmwd |
A |
T |
7: 18,814,472 (GRCm39) |
D374V |
probably damaging |
Het |
| Eea1 |
G |
T |
10: 95,831,475 (GRCm39) |
A189S |
probably benign |
Het |
| Fasn |
A |
G |
11: 120,703,138 (GRCm39) |
V1629A |
probably damaging |
Het |
| Fcgbpl1 |
A |
T |
7: 27,842,225 (GRCm39) |
|
probably benign |
Het |
| Fndc1 |
T |
C |
17: 7,990,471 (GRCm39) |
D1075G |
unknown |
Het |
| Fsip2 |
A |
G |
2: 82,805,202 (GRCm39) |
N507S |
possibly damaging |
Het |
| Gabra5 |
T |
G |
7: 57,063,413 (GRCm39) |
E337A |
probably damaging |
Het |
| Gsg1l |
A |
G |
7: 125,490,841 (GRCm39) |
Y288H |
probably benign |
Het |
| H2-M11 |
A |
T |
17: 36,858,401 (GRCm39) |
D65V |
probably benign |
Het |
| Hmgxb3 |
A |
T |
18: 61,279,606 (GRCm39) |
C736S |
possibly damaging |
Het |
| Hsd3b3 |
A |
T |
3: 98,649,960 (GRCm39) |
I121N |
probably damaging |
Het |
| Ikbke |
GCC |
G |
1: 131,203,004 (GRCm39) |
|
probably null |
Het |
| Il16 |
A |
C |
7: 83,322,302 (GRCm39) |
S338A |
probably benign |
Het |
| Itpr1 |
G |
A |
6: 108,459,867 (GRCm39) |
A2054T |
probably damaging |
Het |
| Lamp3 |
T |
A |
16: 19,474,220 (GRCm39) |
I385F |
probably damaging |
Het |
| Limch1 |
G |
A |
5: 67,039,270 (GRCm39) |
V66I |
possibly damaging |
Het |
| Lmod2 |
A |
G |
6: 24,604,278 (GRCm39) |
R418G |
probably benign |
Het |
| Ly6g6c |
A |
T |
17: 35,288,416 (GRCm39) |
D96V |
probably damaging |
Het |
| Map2k2 |
G |
A |
10: 80,950,947 (GRCm39) |
V131M |
probably damaging |
Het |
| Mapk9 |
T |
C |
11: 49,745,152 (GRCm39) |
V22A |
probably damaging |
Het |
| Mettl2 |
T |
C |
11: 105,019,894 (GRCm39) |
I177T |
probably damaging |
Het |
| Mob4 |
C |
T |
1: 55,191,995 (GRCm39) |
|
probably benign |
Het |
| Mybpc1 |
A |
T |
10: 88,372,286 (GRCm39) |
N781K |
probably benign |
Het |
| Mybpc1 |
T |
C |
10: 88,358,853 (GRCm39) |
I1113V |
probably benign |
Het |
| Myom1 |
A |
G |
17: 71,384,405 (GRCm39) |
T707A |
probably damaging |
Het |
| Ncam2 |
G |
A |
16: 81,287,234 (GRCm39) |
A383T |
probably benign |
Het |
| Nomo1 |
T |
C |
7: 45,715,915 (GRCm39) |
S761P |
probably damaging |
Het |
| Nsd3 |
T |
A |
8: 26,181,161 (GRCm39) |
S921T |
possibly damaging |
Het |
| Omp |
A |
T |
7: 97,794,233 (GRCm39) |
D131E |
probably benign |
Het |
| Or10d1c |
A |
T |
9: 38,893,922 (GRCm39) |
C139* |
probably null |
Het |
| Or4f7d-ps1 |
C |
G |
2: 111,675,040 (GRCm39) |
|
noncoding transcript |
Het |
| Or8d4 |
C |
T |
9: 40,038,514 (GRCm39) |
V248I |
probably damaging |
Het |
| Pard3 |
T |
C |
8: 128,287,950 (GRCm39) |
|
probably benign |
Het |
| Parg |
A |
G |
14: 31,993,625 (GRCm39) |
T286A |
probably damaging |
Het |
| Parp1 |
T |
A |
1: 180,396,600 (GRCm39) |
M1K |
probably null |
Het |
| Pclo |
T |
A |
5: 14,861,694 (GRCm39) |
S4882R |
unknown |
Het |
| Pcnx2 |
C |
T |
8: 126,498,847 (GRCm39) |
E1551K |
probably damaging |
Het |
| Pcyox1l |
A |
G |
18: 61,832,565 (GRCm39) |
Y161H |
probably damaging |
Het |
| Pdzd8 |
A |
T |
19: 59,289,236 (GRCm39) |
C721* |
probably null |
Het |
| Piwil4 |
T |
C |
9: 14,651,761 (GRCm39) |
D90G |
probably benign |
Het |
| Plxdc2 |
T |
A |
2: 16,708,129 (GRCm39) |
C306S |
probably damaging |
Het |
| Plxna2 |
T |
A |
1: 194,326,083 (GRCm39) |
F6I |
probably benign |
Het |
| Prkaa1 |
T |
C |
15: 5,203,886 (GRCm39) |
M265T |
probably benign |
Het |
| Prrc2b |
T |
C |
2: 32,104,212 (GRCm39) |
V1230A |
probably benign |
Het |
| Rfx2 |
T |
C |
17: 57,091,706 (GRCm39) |
E329G |
probably benign |
Het |
| Scg2 |
T |
C |
1: 79,413,636 (GRCm39) |
I322M |
probably damaging |
Het |
| Scly |
T |
A |
1: 91,247,850 (GRCm39) |
N399K |
probably damaging |
Het |
| Sec23b |
T |
A |
2: 144,428,281 (GRCm39) |
|
probably null |
Het |
| Sephs2 |
A |
T |
7: 126,872,219 (GRCm39) |
Y291* |
probably null |
Het |
| Slc45a3 |
T |
C |
1: 131,909,285 (GRCm39) |
I494T |
possibly damaging |
Het |
| Slc6a21 |
C |
A |
7: 44,929,535 (GRCm39) |
Y76* |
probably null |
Het |
| Slfn14 |
T |
A |
11: 83,167,098 (GRCm39) |
I806L |
possibly damaging |
Het |
| Slfn4 |
T |
A |
11: 83,077,844 (GRCm39) |
S211T |
probably benign |
Het |
| Sptbn4 |
A |
G |
7: 27,071,577 (GRCm39) |
V1624A |
probably damaging |
Het |
| Sugp1 |
T |
A |
8: 70,523,834 (GRCm39) |
M567K |
probably damaging |
Het |
| Tmem121 |
A |
T |
12: 113,152,348 (GRCm39) |
M189L |
probably benign |
Het |
| Tmem201 |
A |
G |
4: 149,806,727 (GRCm39) |
S444P |
probably damaging |
Het |
| Tmem63a |
T |
C |
1: 180,800,751 (GRCm39) |
V744A |
probably benign |
Het |
| Tnrc18 |
G |
A |
5: 142,717,380 (GRCm39) |
S2358F |
unknown |
Het |
| Ubash3b |
A |
G |
9: 40,929,405 (GRCm39) |
V404A |
probably benign |
Het |
| Unc13c |
A |
T |
9: 73,656,821 (GRCm39) |
C1127S |
probably damaging |
Het |
| Unc5a |
T |
C |
13: 55,145,042 (GRCm39) |
V253A |
probably benign |
Het |
| Vmn1r-ps123 |
C |
T |
13: 23,180,535 (GRCm39) |
|
noncoding transcript |
Het |
| Wdr74 |
A |
G |
19: 8,716,849 (GRCm39) |
E253G |
possibly damaging |
Het |
| Wwox |
T |
C |
8: 115,174,988 (GRCm39) |
Y107H |
probably damaging |
Het |
| Zdhhc22 |
A |
T |
12: 87,035,012 (GRCm39) |
Y147N |
probably damaging |
Het |
| Zfp131 |
T |
C |
13: 120,250,491 (GRCm39) |
H44R |
possibly damaging |
Het |
| Zfp235 |
A |
G |
7: 23,840,384 (GRCm39) |
T268A |
probably benign |
Het |
| Zfp280d |
T |
C |
9: 72,206,140 (GRCm39) |
|
probably benign |
Het |
| Zfp358 |
T |
C |
8: 3,546,170 (GRCm39) |
S251P |
probably damaging |
Het |
|
| Other mutations in Dennd4a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00476:Dennd4a
|
APN |
9 |
64,819,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01610:Dennd4a
|
APN |
9 |
64,814,166 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01788:Dennd4a
|
APN |
9 |
64,749,903 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01827:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL01828:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL01829:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL01979:Dennd4a
|
APN |
9 |
64,801,691 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02100:Dennd4a
|
APN |
9 |
64,816,988 (GRCm39) |
splice site |
probably benign |
|
|
IGL02339:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL02341:Dennd4a
|
APN |
9 |
64,749,843 (GRCm39) |
nonsense |
probably null |
|
|
IGL02584:Dennd4a
|
APN |
9 |
64,758,580 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02607:Dennd4a
|
APN |
9 |
64,769,609 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02654:Dennd4a
|
APN |
9 |
64,817,473 (GRCm39) |
splice site |
probably benign |
|
|
IGL02701:Dennd4a
|
APN |
9 |
64,804,635 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL03051:Dennd4a
|
APN |
9 |
64,769,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03257:Dennd4a
|
APN |
9 |
64,779,156 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
IGL03346:Dennd4a
|
APN |
9 |
64,795,808 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL03349:Dennd4a
|
APN |
9 |
64,796,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03398:Dennd4a
|
APN |
9 |
64,779,164 (GRCm39) |
missense |
probably benign |
0.32 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,803,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0010:Dennd4a
|
UTSW |
9 |
64,803,997 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0129:Dennd4a
|
UTSW |
9 |
64,800,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0220:Dennd4a
|
UTSW |
9 |
64,759,727 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0396:Dennd4a
|
UTSW |
9 |
64,769,673 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0881:Dennd4a
|
UTSW |
9 |
64,758,665 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1225:Dennd4a
|
UTSW |
9 |
64,818,957 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1311:Dennd4a
|
UTSW |
9 |
64,817,286 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1448:Dennd4a
|
UTSW |
9 |
64,813,327 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1450:Dennd4a
|
UTSW |
9 |
64,818,947 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1630:Dennd4a
|
UTSW |
9 |
64,779,164 (GRCm39) |
missense |
probably benign |
0.32 |
|
R1709:Dennd4a
|
UTSW |
9 |
64,796,887 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1824:Dennd4a
|
UTSW |
9 |
64,766,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1851:Dennd4a
|
UTSW |
9 |
64,769,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1870:Dennd4a
|
UTSW |
9 |
64,804,516 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1900:Dennd4a
|
UTSW |
9 |
64,804,618 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1911:Dennd4a
|
UTSW |
9 |
64,796,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1938:Dennd4a
|
UTSW |
9 |
64,749,772 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1954:Dennd4a
|
UTSW |
9 |
64,759,749 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1955:Dennd4a
|
UTSW |
9 |
64,759,749 (GRCm39) |
missense |
probably benign |
0.02 |
|
R2049:Dennd4a
|
UTSW |
9 |
64,796,887 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2129:Dennd4a
|
UTSW |
9 |
64,813,256 (GRCm39) |
splice site |
probably null |
|
|
R2138:Dennd4a
|
UTSW |
9 |
64,796,619 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2929:Dennd4a
|
UTSW |
9 |
64,759,699 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R3083:Dennd4a
|
UTSW |
9 |
64,813,363 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3108:Dennd4a
|
UTSW |
9 |
64,819,669 (GRCm39) |
missense |
probably benign |
0.23 |
|
R3176:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3177:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3276:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3277:Dennd4a
|
UTSW |
9 |
64,796,275 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3890:Dennd4a
|
UTSW |
9 |
64,779,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3953:Dennd4a
|
UTSW |
9 |
64,759,857 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3963:Dennd4a
|
UTSW |
9 |
64,769,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4059:Dennd4a
|
UTSW |
9 |
64,819,174 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4499:Dennd4a
|
UTSW |
9 |
64,817,405 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4500:Dennd4a
|
UTSW |
9 |
64,817,405 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4501:Dennd4a
|
UTSW |
9 |
64,817,405 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R4671:Dennd4a
|
UTSW |
9 |
64,801,689 (GRCm39) |
missense |
probably benign |
|
|
R4701:Dennd4a
|
UTSW |
9 |
64,804,639 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R4821:Dennd4a
|
UTSW |
9 |
64,804,531 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4829:Dennd4a
|
UTSW |
9 |
64,796,338 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4881:Dennd4a
|
UTSW |
9 |
64,746,126 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R4962:Dennd4a
|
UTSW |
9 |
64,813,285 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5225:Dennd4a
|
UTSW |
9 |
64,796,210 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5557:Dennd4a
|
UTSW |
9 |
64,811,509 (GRCm39) |
missense |
probably benign |
0.07 |
|
R5649:Dennd4a
|
UTSW |
9 |
64,758,491 (GRCm39) |
splice site |
probably null |
|
|
R5868:Dennd4a
|
UTSW |
9 |
64,804,011 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5876:Dennd4a
|
UTSW |
9 |
64,819,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6052:Dennd4a
|
UTSW |
9 |
64,794,227 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6411:Dennd4a
|
UTSW |
9 |
64,779,181 (GRCm39) |
missense |
probably benign |
0.04 |
|
R6596:Dennd4a
|
UTSW |
9 |
64,759,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6668:Dennd4a
|
UTSW |
9 |
64,794,247 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6915:Dennd4a
|
UTSW |
9 |
64,759,771 (GRCm39) |
nonsense |
probably null |
|
|
R7056:Dennd4a
|
UTSW |
9 |
64,814,205 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7107:Dennd4a
|
UTSW |
9 |
64,801,681 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R7203:Dennd4a
|
UTSW |
9 |
64,803,756 (GRCm39) |
missense |
probably benign |
0.05 |
|
R7238:Dennd4a
|
UTSW |
9 |
64,769,238 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7373:Dennd4a
|
UTSW |
9 |
64,804,551 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7454:Dennd4a
|
UTSW |
9 |
64,759,852 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7546:Dennd4a
|
UTSW |
9 |
64,780,326 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7590:Dennd4a
|
UTSW |
9 |
64,795,869 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7662:Dennd4a
|
UTSW |
9 |
64,759,713 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7782:Dennd4a
|
UTSW |
9 |
64,814,202 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7909:Dennd4a
|
UTSW |
9 |
64,780,275 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R7976:Dennd4a
|
UTSW |
9 |
64,759,794 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8026:Dennd4a
|
UTSW |
9 |
64,780,312 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8034:Dennd4a
|
UTSW |
9 |
64,795,850 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8089:Dennd4a
|
UTSW |
9 |
64,756,457 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8298:Dennd4a
|
UTSW |
9 |
64,814,157 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8397:Dennd4a
|
UTSW |
9 |
64,796,391 (GRCm39) |
missense |
probably benign |
|
|
R8425:Dennd4a
|
UTSW |
9 |
64,746,256 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8495:Dennd4a
|
UTSW |
9 |
64,794,161 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8855:Dennd4a
|
UTSW |
9 |
64,819,672 (GRCm39) |
missense |
probably benign |
|
|
R9219:Dennd4a
|
UTSW |
9 |
64,796,376 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9275:Dennd4a
|
UTSW |
9 |
64,749,906 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9376:Dennd4a
|
UTSW |
9 |
64,819,974 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9485:Dennd4a
|
UTSW |
9 |
64,814,388 (GRCm39) |
nonsense |
probably null |
|
|
R9672:Dennd4a
|
UTSW |
9 |
64,800,640 (GRCm39) |
missense |
probably benign |
|
|
R9746:Dennd4a
|
UTSW |
9 |
64,801,793 (GRCm39) |
missense |
probably benign |
|
|
X0026:Dennd4a
|
UTSW |
9 |
64,804,602 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
Z1088:Dennd4a
|
UTSW |
9 |
64,779,304 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTTGAGGACACAAATGAAGCAC -3'
(R):5'- GACACCGCCCACTTTTGATC -3'
Sequencing Primer
(F):5'- GCAGGTGCTTTAGGAAAAGGC -3'
(R):5'- GATCCATCTGTTTCAGTGTCTAAATC -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation