Incidental Mutation 'R4887:Alpk1'
| ID |
376954 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Alpk1
|
| Ensembl Gene |
ENSMUSG00000028028 |
| Gene Name |
alpha-kinase 1 |
| Synonyms |
8430410J10Rik |
| MMRRC Submission |
041979-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4887 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
127463959-127574176 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 127467124 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glycine to Arginine
at position 1052
(G1052R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000143223
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029662]
[ENSMUST00000198955]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000029662
AA Change: G1052R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000029662
Gene: ENSMUSG00000028028
AA Change: G1052R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
85 |
97 |
N/A |
INTRINSIC |
|
low complexity region
|
618 |
628 |
N/A |
INTRINSIC |
|
low complexity region
|
700 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
902 |
914 |
N/A |
INTRINSIC |
|
low complexity region
|
924 |
947 |
N/A |
INTRINSIC |
|
Alpha_kinase
|
1008 |
1215 |
1.03e-81 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000160586
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000198955
AA Change: G1052R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000143223
Gene: ENSMUSG00000028028
AA Change: G1052R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
85 |
97 |
N/A |
INTRINSIC |
|
low complexity region
|
618 |
628 |
N/A |
INTRINSIC |
|
low complexity region
|
700 |
714 |
N/A |
INTRINSIC |
|
low complexity region
|
902 |
914 |
N/A |
INTRINSIC |
|
low complexity region
|
924 |
947 |
N/A |
INTRINSIC |
|
Alpha_kinase
|
1008 |
1215 |
1.03e-81 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes an alpha kinase. Mice which were homozygous for disrupted copies of this gene exhibited coordination defects (PMID: 21208416). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Dec 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310009B15Rik |
A |
C |
1: 138,779,903 (GRCm39) |
Y116* |
probably null |
Het |
| Abtb3 |
C |
T |
10: 85,223,242 (GRCm39) |
T17M |
unknown |
Het |
| Acer3 |
T |
C |
7: 97,906,908 (GRCm39) |
T91A |
possibly damaging |
Het |
| Acsbg3 |
A |
T |
17: 57,183,324 (GRCm39) |
I22F |
possibly damaging |
Het |
| Adam12 |
T |
C |
7: 133,774,550 (GRCm39) |
K20E |
possibly damaging |
Het |
| Adamtsl3 |
T |
C |
7: 82,223,822 (GRCm39) |
V275A |
possibly damaging |
Het |
| Afg1l |
C |
T |
10: 42,330,374 (GRCm39) |
V98I |
probably benign |
Het |
| Ajm1 |
G |
A |
2: 25,469,759 (GRCm39) |
R51C |
possibly damaging |
Het |
| Anln |
A |
T |
9: 22,291,484 (GRCm39) |
S115T |
possibly damaging |
Het |
| Apob |
T |
A |
12: 8,063,099 (GRCm39) |
N3827K |
probably damaging |
Het |
| Aqr |
G |
A |
2: 113,980,990 (GRCm39) |
L264F |
probably damaging |
Het |
| Arhgap33 |
T |
C |
7: 30,231,617 (GRCm39) |
S123G |
probably damaging |
Het |
| Arvcf |
C |
T |
16: 18,216,863 (GRCm39) |
R333* |
probably null |
Het |
| Brca2 |
T |
A |
5: 150,480,402 (GRCm39) |
L2724Q |
probably damaging |
Het |
| C2cd6 |
T |
A |
1: 59,133,893 (GRCm39) |
T43S |
probably benign |
Het |
| Cacna1h |
A |
G |
17: 25,596,261 (GRCm39) |
V1920A |
possibly damaging |
Het |
| Capsl |
A |
T |
15: 9,457,858 (GRCm39) |
I26F |
possibly damaging |
Het |
| Card10 |
A |
T |
15: 78,665,724 (GRCm39) |
V673E |
possibly damaging |
Het |
| Catspere2 |
A |
G |
1: 177,931,515 (GRCm39) |
Y478C |
unknown |
Het |
| Ccar1 |
A |
G |
10: 62,588,997 (GRCm39) |
S829P |
unknown |
Het |
| Ccdc121 |
A |
G |
5: 31,643,596 (GRCm39) |
I109V |
probably benign |
Het |
| Cdc42bpa |
T |
C |
1: 179,972,200 (GRCm39) |
M1334T |
possibly damaging |
Het |
| Ceacam2 |
C |
T |
7: 25,220,257 (GRCm39) |
C267Y |
probably benign |
Het |
| Cep68 |
G |
A |
11: 20,189,239 (GRCm39) |
T591M |
probably benign |
Het |
| Chil4 |
T |
C |
3: 106,111,460 (GRCm39) |
K218R |
probably benign |
Het |
| Cldn14 |
G |
T |
16: 93,716,747 (GRCm39) |
T33K |
possibly damaging |
Het |
| Copa |
T |
A |
1: 171,919,843 (GRCm39) |
C140S |
probably benign |
Het |
| Coq6 |
T |
C |
12: 84,419,070 (GRCm39) |
L358P |
probably damaging |
Het |
| Cyfip1 |
C |
T |
7: 55,521,816 (GRCm39) |
P40L |
probably damaging |
Het |
| Dennd2a |
A |
C |
6: 39,474,093 (GRCm39) |
S414A |
probably benign |
Het |
| Dpm1 |
T |
C |
2: 168,059,679 (GRCm39) |
N139S |
probably benign |
Het |
| Dpp7 |
T |
A |
2: 25,242,770 (GRCm39) |
|
probably null |
Het |
| Ednrb |
T |
C |
14: 104,057,447 (GRCm39) |
I372V |
possibly damaging |
Het |
| Edrf1 |
G |
T |
7: 133,260,339 (GRCm39) |
M83I |
probably damaging |
Het |
| Fam135a |
G |
A |
1: 24,063,334 (GRCm39) |
Q1087* |
probably null |
Het |
| Fancg |
T |
C |
4: 43,006,866 (GRCm39) |
T275A |
probably benign |
Het |
| Fbn1 |
T |
A |
2: 125,151,694 (GRCm39) |
H2520L |
probably damaging |
Het |
| Fmn2 |
T |
C |
1: 174,409,527 (GRCm39) |
S587P |
unknown |
Het |
| Foxr2 |
A |
G |
X: 151,913,312 (GRCm39) |
Q61R |
probably damaging |
Het |
| Frrs1 |
A |
G |
3: 116,696,065 (GRCm39) |
*124W |
probably null |
Het |
| Gm7535 |
T |
A |
17: 18,131,333 (GRCm39) |
|
probably benign |
Het |
| H4c1 |
T |
C |
13: 23,944,935 (GRCm39) |
D69G |
probably damaging |
Het |
| Herc3 |
T |
C |
6: 58,864,484 (GRCm39) |
V706A |
probably damaging |
Het |
| Hivep3 |
A |
G |
4: 119,980,131 (GRCm39) |
E1723G |
probably damaging |
Het |
| Igsf9b |
A |
G |
9: 27,233,946 (GRCm39) |
I382V |
probably benign |
Het |
| Ints1 |
G |
T |
5: 139,756,911 (GRCm39) |
T467N |
possibly damaging |
Het |
| Iqca1 |
G |
A |
1: 89,973,423 (GRCm39) |
T783M |
probably damaging |
Het |
| Kng1 |
A |
G |
16: 22,886,448 (GRCm39) |
K131R |
possibly damaging |
Het |
| Krt35 |
T |
C |
11: 99,983,956 (GRCm39) |
Y348C |
probably damaging |
Het |
| Ldlrad3 |
A |
G |
2: 101,943,881 (GRCm39) |
C64R |
probably damaging |
Het |
| Lilrb4b |
C |
T |
10: 51,360,616 (GRCm39) |
A272V |
possibly damaging |
Het |
| Lrrc37 |
T |
C |
11: 103,505,698 (GRCm39) |
H2090R |
probably benign |
Het |
| Ltn1 |
A |
T |
16: 87,195,697 (GRCm39) |
C1276* |
probably null |
Het |
| Matn1 |
G |
A |
4: 130,679,425 (GRCm39) |
A360T |
probably benign |
Het |
| Minpp1 |
G |
A |
19: 32,475,784 (GRCm39) |
V306I |
probably benign |
Het |
| Mkx |
G |
A |
18: 6,992,904 (GRCm39) |
R127W |
probably damaging |
Het |
| Mrpl48 |
G |
T |
7: 100,195,616 (GRCm39) |
|
probably benign |
Het |
| Ms4a2 |
A |
G |
19: 11,595,793 (GRCm39) |
L166S |
possibly damaging |
Het |
| Mtus2 |
T |
A |
5: 148,013,913 (GRCm39) |
Y235* |
probably null |
Het |
| Myh4 |
G |
T |
11: 67,131,880 (GRCm39) |
W113C |
probably damaging |
Het |
| Nav2 |
T |
A |
7: 49,198,182 (GRCm39) |
C1270* |
probably null |
Het |
| Ncoa5 |
A |
G |
2: 164,844,070 (GRCm39) |
L111P |
probably damaging |
Het |
| Nup107 |
T |
C |
10: 117,606,383 (GRCm39) |
Y453C |
probably damaging |
Het |
| Oca2 |
C |
T |
7: 55,980,106 (GRCm39) |
Q604* |
probably null |
Het |
| Or13a19 |
T |
C |
7: 139,903,014 (GRCm39) |
M134T |
probably benign |
Het |
| Or13p5 |
A |
C |
4: 118,591,885 (GRCm39) |
H53P |
probably benign |
Het |
| Or14j10 |
A |
T |
17: 37,934,782 (GRCm39) |
V248D |
probably damaging |
Het |
| Or5p58 |
T |
A |
7: 107,694,303 (GRCm39) |
N158I |
probably benign |
Het |
| Or8g33 |
T |
C |
9: 39,337,531 (GRCm39) |
T279A |
possibly damaging |
Het |
| Pde3a |
G |
T |
6: 141,416,668 (GRCm39) |
G514V |
possibly damaging |
Het |
| Pik3cb |
A |
T |
9: 98,983,381 (GRCm39) |
C76S |
probably damaging |
Het |
| Plk1 |
T |
C |
7: 121,767,828 (GRCm39) |
V411A |
probably damaging |
Het |
| Pole |
C |
T |
5: 110,472,619 (GRCm39) |
P1600L |
probably damaging |
Het |
| Prr36 |
T |
C |
8: 4,260,881 (GRCm39) |
T979A |
probably benign |
Het |
| Rdh7 |
T |
A |
10: 127,721,590 (GRCm39) |
T229S |
probably benign |
Het |
| Rnpepl1 |
A |
T |
1: 92,842,835 (GRCm39) |
T140S |
probably damaging |
Het |
| Rps6kc1 |
A |
T |
1: 190,530,891 (GRCm39) |
S947T |
probably benign |
Het |
| Rtl1 |
A |
G |
12: 109,558,138 (GRCm39) |
F1234L |
probably damaging |
Het |
| Sdc1 |
G |
A |
12: 8,841,708 (GRCm39) |
M279I |
probably damaging |
Het |
| Siae |
T |
C |
9: 37,539,096 (GRCm39) |
L169P |
possibly damaging |
Het |
| Slc22a22 |
C |
T |
15: 57,113,148 (GRCm39) |
V364I |
probably benign |
Het |
| Sltm |
G |
T |
9: 70,496,260 (GRCm39) |
V932F |
probably damaging |
Het |
| Smad1 |
A |
G |
8: 80,076,381 (GRCm39) |
L279P |
probably damaging |
Het |
| Spag17 |
G |
T |
3: 99,958,147 (GRCm39) |
G935V |
probably damaging |
Het |
| Srgap3 |
A |
G |
6: 112,723,895 (GRCm39) |
S546P |
probably damaging |
Het |
| Stxbp5 |
T |
C |
10: 9,684,844 (GRCm39) |
I519V |
probably benign |
Het |
| Syt16 |
A |
T |
12: 74,176,160 (GRCm39) |
I10F |
probably damaging |
Het |
| Trim43b |
C |
G |
9: 88,973,365 (GRCm39) |
G123R |
probably damaging |
Het |
| Ubr3 |
T |
C |
2: 69,843,475 (GRCm39) |
Y1572H |
probably damaging |
Het |
| Umodl1 |
G |
A |
17: 31,227,639 (GRCm39) |
R1324H |
probably benign |
Het |
| Vmn2r44 |
A |
T |
7: 8,380,985 (GRCm39) |
W303R |
probably benign |
Het |
| Wdr93 |
T |
C |
7: 79,435,522 (GRCm39) |
Y684H |
probably damaging |
Het |
| Wnk2 |
G |
A |
13: 49,224,478 (GRCm39) |
R268C |
probably damaging |
Het |
| Zfp438 |
C |
T |
18: 5,213,776 (GRCm39) |
C394Y |
possibly damaging |
Het |
|
| Other mutations in Alpk1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00096:Alpk1
|
APN |
3 |
127,474,692 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00722:Alpk1
|
APN |
3 |
127,473,862 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01066:Alpk1
|
APN |
3 |
127,473,874 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL01351:Alpk1
|
APN |
3 |
127,466,011 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL01412:Alpk1
|
APN |
3 |
127,473,621 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
IGL01469:Alpk1
|
APN |
3 |
127,471,401 (GRCm39) |
splice site |
probably null |
|
|
IGL01585:Alpk1
|
APN |
3 |
127,473,462 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02308:Alpk1
|
APN |
3 |
127,522,931 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02325:Alpk1
|
APN |
3 |
127,473,552 (GRCm39) |
missense |
probably benign |
0.43 |
|
IGL02458:Alpk1
|
APN |
3 |
127,474,968 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02553:Alpk1
|
APN |
3 |
127,466,970 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02717:Alpk1
|
APN |
3 |
127,474,749 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL02729:Alpk1
|
APN |
3 |
127,474,721 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
IGL02832:Alpk1
|
APN |
3 |
127,473,592 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
IGL02892:Alpk1
|
APN |
3 |
127,473,771 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL03178:Alpk1
|
APN |
3 |
127,473,870 (GRCm39) |
nonsense |
probably null |
|
|
R0427:Alpk1
|
UTSW |
3 |
127,464,720 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0981:Alpk1
|
UTSW |
3 |
127,473,051 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R1174:Alpk1
|
UTSW |
3 |
127,474,459 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1793:Alpk1
|
UTSW |
3 |
127,471,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1859:Alpk1
|
UTSW |
3 |
127,474,749 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R2173:Alpk1
|
UTSW |
3 |
127,477,239 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2235:Alpk1
|
UTSW |
3 |
127,474,569 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2373:Alpk1
|
UTSW |
3 |
127,473,457 (GRCm39) |
missense |
probably benign |
0.00 |
|
R3803:Alpk1
|
UTSW |
3 |
127,473,486 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R3927:Alpk1
|
UTSW |
3 |
127,471,365 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4356:Alpk1
|
UTSW |
3 |
127,523,022 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4357:Alpk1
|
UTSW |
3 |
127,523,022 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4358:Alpk1
|
UTSW |
3 |
127,523,022 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4379:Alpk1
|
UTSW |
3 |
127,523,022 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4381:Alpk1
|
UTSW |
3 |
127,523,022 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4470:Alpk1
|
UTSW |
3 |
127,473,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4471:Alpk1
|
UTSW |
3 |
127,473,175 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4473:Alpk1
|
UTSW |
3 |
127,473,667 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4474:Alpk1
|
UTSW |
3 |
127,473,667 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4476:Alpk1
|
UTSW |
3 |
127,473,667 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4512:Alpk1
|
UTSW |
3 |
127,478,120 (GRCm39) |
intron |
probably benign |
|
|
R4594:Alpk1
|
UTSW |
3 |
127,477,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4678:Alpk1
|
UTSW |
3 |
127,473,507 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4707:Alpk1
|
UTSW |
3 |
127,481,241 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4784:Alpk1
|
UTSW |
3 |
127,481,241 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4785:Alpk1
|
UTSW |
3 |
127,481,241 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4820:Alpk1
|
UTSW |
3 |
127,464,708 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5088:Alpk1
|
UTSW |
3 |
127,478,969 (GRCm39) |
splice site |
probably benign |
|
|
R5169:Alpk1
|
UTSW |
3 |
127,464,750 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5280:Alpk1
|
UTSW |
3 |
127,474,813 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5351:Alpk1
|
UTSW |
3 |
127,522,941 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5478:Alpk1
|
UTSW |
3 |
127,471,368 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5627:Alpk1
|
UTSW |
3 |
127,474,296 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5781:Alpk1
|
UTSW |
3 |
127,473,684 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5842:Alpk1
|
UTSW |
3 |
127,474,618 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5847:Alpk1
|
UTSW |
3 |
127,473,723 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5940:Alpk1
|
UTSW |
3 |
127,464,595 (GRCm39) |
missense |
probably benign |
|
|
R6187:Alpk1
|
UTSW |
3 |
127,466,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6306:Alpk1
|
UTSW |
3 |
127,479,965 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6414:Alpk1
|
UTSW |
3 |
127,473,858 (GRCm39) |
missense |
probably benign |
|
|
R6701:Alpk1
|
UTSW |
3 |
127,522,985 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6735:Alpk1
|
UTSW |
3 |
127,518,098 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6850:Alpk1
|
UTSW |
3 |
127,523,012 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R7173:Alpk1
|
UTSW |
3 |
127,478,024 (GRCm39) |
nonsense |
probably null |
|
|
R7258:Alpk1
|
UTSW |
3 |
127,518,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7412:Alpk1
|
UTSW |
3 |
127,489,382 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7412:Alpk1
|
UTSW |
3 |
127,466,143 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7498:Alpk1
|
UTSW |
3 |
127,473,427 (GRCm39) |
missense |
probably benign |
0.22 |
|
R7635:Alpk1
|
UTSW |
3 |
127,489,310 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7660:Alpk1
|
UTSW |
3 |
127,474,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7682:Alpk1
|
UTSW |
3 |
127,466,195 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7732:Alpk1
|
UTSW |
3 |
127,478,041 (GRCm39) |
missense |
|
|
|
R7827:Alpk1
|
UTSW |
3 |
127,473,700 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8029:Alpk1
|
UTSW |
3 |
127,522,934 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8383:Alpk1
|
UTSW |
3 |
127,518,085 (GRCm39) |
missense |
probably benign |
0.41 |
|
R8478:Alpk1
|
UTSW |
3 |
127,522,961 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8765:Alpk1
|
UTSW |
3 |
127,466,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Alpk1
|
UTSW |
3 |
127,478,024 (GRCm39) |
nonsense |
probably null |
|
|
R8907:Alpk1
|
UTSW |
3 |
127,474,642 (GRCm39) |
nonsense |
probably null |
|
|
R8972:Alpk1
|
UTSW |
3 |
127,473,232 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8974:Alpk1
|
UTSW |
3 |
127,473,580 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9039:Alpk1
|
UTSW |
3 |
127,473,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9202:Alpk1
|
UTSW |
3 |
127,479,938 (GRCm39) |
missense |
|
|
|
R9394:Alpk1
|
UTSW |
3 |
127,466,187 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9421:Alpk1
|
UTSW |
3 |
127,467,069 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9436:Alpk1
|
UTSW |
3 |
127,478,924 (GRCm39) |
missense |
|
|
|
R9785:Alpk1
|
UTSW |
3 |
127,473,594 (GRCm39) |
missense |
probably benign |
0.22 |
|
Z1176:Alpk1
|
UTSW |
3 |
127,467,087 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Alpk1
|
UTSW |
3 |
127,478,956 (GRCm39) |
missense |
|
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCTTGTTTAATTAACTCATGCTTTACC -3'
(R):5'- AAGTTGAGAGAGTTGATATTGACTAGA -3'
Sequencing Primer
(F):5'- GCTTTACCAGTAATATTGTAGAGGG -3'
(R):5'- ACACCTGCTACATATGTGTGG -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation