Incidental Mutation 'R4887:Ltn1'
| ID |
377017 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ltn1
|
| Ensembl Gene |
ENSMUSG00000052299 |
| Gene Name |
listerin E3 ubiquitin protein ligase 1 |
| Synonyms |
Listerin, Zfp294, Rnf160, 4930528H02Rik |
| MMRRC Submission |
041979-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4887 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
87173539-87229500 bp(-) (GRCm39) |
| Type of Mutation |
nonsense |
| DNA Base Change (assembly) |
A to T
at 87195697 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Cysteine to Stop codon
at position 1276
(C1276*)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000038775
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039449]
|
| AlphaFold |
Q6A009 |
| Predicted Effect |
probably null
Transcript: ENSMUST00000039449
AA Change: C1276*
|
| SMART Domains |
Protein: ENSMUSP00000038775
Gene: ENSMUSG00000052299
AA Change: C1276*
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
160 |
176 |
N/A |
INTRINSIC |
|
low complexity region
|
400 |
410 |
N/A |
INTRINSIC |
|
low complexity region
|
509 |
522 |
N/A |
INTRINSIC |
|
low complexity region
|
553 |
569 |
N/A |
INTRINSIC |
|
low complexity region
|
815 |
832 |
N/A |
INTRINSIC |
|
low complexity region
|
1380 |
1392 |
N/A |
INTRINSIC |
|
low complexity region
|
1427 |
1451 |
N/A |
INTRINSIC |
|
RING
|
1716 |
1762 |
1.05e-1 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Like most RING finger proteins, LTN1 functions as an E3 ubiquitin ligase (Chu et al., 2009 [PubMed 19196968]).[supplied by OMIM, Nov 2010]
PHENOTYPE: Mice homozygous for a gene trap allele display embryonic lethality. Mice homozygous for a point mutation display progressive neuron degeneration and age dependent motor deficits. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 94 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310009B15Rik |
A |
C |
1: 138,779,903 (GRCm39) |
Y116* |
probably null |
Het |
| Abtb3 |
C |
T |
10: 85,223,242 (GRCm39) |
T17M |
unknown |
Het |
| Acer3 |
T |
C |
7: 97,906,908 (GRCm39) |
T91A |
possibly damaging |
Het |
| Acsbg3 |
A |
T |
17: 57,183,324 (GRCm39) |
I22F |
possibly damaging |
Het |
| Adam12 |
T |
C |
7: 133,774,550 (GRCm39) |
K20E |
possibly damaging |
Het |
| Adamtsl3 |
T |
C |
7: 82,223,822 (GRCm39) |
V275A |
possibly damaging |
Het |
| Afg1l |
C |
T |
10: 42,330,374 (GRCm39) |
V98I |
probably benign |
Het |
| Ajm1 |
G |
A |
2: 25,469,759 (GRCm39) |
R51C |
possibly damaging |
Het |
| Alpk1 |
C |
T |
3: 127,467,124 (GRCm39) |
G1052R |
probably damaging |
Het |
| Anln |
A |
T |
9: 22,291,484 (GRCm39) |
S115T |
possibly damaging |
Het |
| Apob |
T |
A |
12: 8,063,099 (GRCm39) |
N3827K |
probably damaging |
Het |
| Aqr |
G |
A |
2: 113,980,990 (GRCm39) |
L264F |
probably damaging |
Het |
| Arhgap33 |
T |
C |
7: 30,231,617 (GRCm39) |
S123G |
probably damaging |
Het |
| Arvcf |
C |
T |
16: 18,216,863 (GRCm39) |
R333* |
probably null |
Het |
| Brca2 |
T |
A |
5: 150,480,402 (GRCm39) |
L2724Q |
probably damaging |
Het |
| C2cd6 |
T |
A |
1: 59,133,893 (GRCm39) |
T43S |
probably benign |
Het |
| Cacna1h |
A |
G |
17: 25,596,261 (GRCm39) |
V1920A |
possibly damaging |
Het |
| Capsl |
A |
T |
15: 9,457,858 (GRCm39) |
I26F |
possibly damaging |
Het |
| Card10 |
A |
T |
15: 78,665,724 (GRCm39) |
V673E |
possibly damaging |
Het |
| Catspere2 |
A |
G |
1: 177,931,515 (GRCm39) |
Y478C |
unknown |
Het |
| Ccar1 |
A |
G |
10: 62,588,997 (GRCm39) |
S829P |
unknown |
Het |
| Ccdc121 |
A |
G |
5: 31,643,596 (GRCm39) |
I109V |
probably benign |
Het |
| Cdc42bpa |
T |
C |
1: 179,972,200 (GRCm39) |
M1334T |
possibly damaging |
Het |
| Ceacam2 |
C |
T |
7: 25,220,257 (GRCm39) |
C267Y |
probably benign |
Het |
| Cep68 |
G |
A |
11: 20,189,239 (GRCm39) |
T591M |
probably benign |
Het |
| Chil4 |
T |
C |
3: 106,111,460 (GRCm39) |
K218R |
probably benign |
Het |
| Cldn14 |
G |
T |
16: 93,716,747 (GRCm39) |
T33K |
possibly damaging |
Het |
| Copa |
T |
A |
1: 171,919,843 (GRCm39) |
C140S |
probably benign |
Het |
| Coq6 |
T |
C |
12: 84,419,070 (GRCm39) |
L358P |
probably damaging |
Het |
| Cyfip1 |
C |
T |
7: 55,521,816 (GRCm39) |
P40L |
probably damaging |
Het |
| Dennd2a |
A |
C |
6: 39,474,093 (GRCm39) |
S414A |
probably benign |
Het |
| Dpm1 |
T |
C |
2: 168,059,679 (GRCm39) |
N139S |
probably benign |
Het |
| Dpp7 |
T |
A |
2: 25,242,770 (GRCm39) |
|
probably null |
Het |
| Ednrb |
T |
C |
14: 104,057,447 (GRCm39) |
I372V |
possibly damaging |
Het |
| Edrf1 |
G |
T |
7: 133,260,339 (GRCm39) |
M83I |
probably damaging |
Het |
| Fam135a |
G |
A |
1: 24,063,334 (GRCm39) |
Q1087* |
probably null |
Het |
| Fancg |
T |
C |
4: 43,006,866 (GRCm39) |
T275A |
probably benign |
Het |
| Fbn1 |
T |
A |
2: 125,151,694 (GRCm39) |
H2520L |
probably damaging |
Het |
| Fmn2 |
T |
C |
1: 174,409,527 (GRCm39) |
S587P |
unknown |
Het |
| Foxr2 |
A |
G |
X: 151,913,312 (GRCm39) |
Q61R |
probably damaging |
Het |
| Frrs1 |
A |
G |
3: 116,696,065 (GRCm39) |
*124W |
probably null |
Het |
| Gm7535 |
T |
A |
17: 18,131,333 (GRCm39) |
|
probably benign |
Het |
| H4c1 |
T |
C |
13: 23,944,935 (GRCm39) |
D69G |
probably damaging |
Het |
| Herc3 |
T |
C |
6: 58,864,484 (GRCm39) |
V706A |
probably damaging |
Het |
| Hivep3 |
A |
G |
4: 119,980,131 (GRCm39) |
E1723G |
probably damaging |
Het |
| Igsf9b |
A |
G |
9: 27,233,946 (GRCm39) |
I382V |
probably benign |
Het |
| Ints1 |
G |
T |
5: 139,756,911 (GRCm39) |
T467N |
possibly damaging |
Het |
| Iqca1 |
G |
A |
1: 89,973,423 (GRCm39) |
T783M |
probably damaging |
Het |
| Kng1 |
A |
G |
16: 22,886,448 (GRCm39) |
K131R |
possibly damaging |
Het |
| Krt35 |
T |
C |
11: 99,983,956 (GRCm39) |
Y348C |
probably damaging |
Het |
| Ldlrad3 |
A |
G |
2: 101,943,881 (GRCm39) |
C64R |
probably damaging |
Het |
| Lilrb4b |
C |
T |
10: 51,360,616 (GRCm39) |
A272V |
possibly damaging |
Het |
| Lrrc37 |
T |
C |
11: 103,505,698 (GRCm39) |
H2090R |
probably benign |
Het |
| Matn1 |
G |
A |
4: 130,679,425 (GRCm39) |
A360T |
probably benign |
Het |
| Minpp1 |
G |
A |
19: 32,475,784 (GRCm39) |
V306I |
probably benign |
Het |
| Mkx |
G |
A |
18: 6,992,904 (GRCm39) |
R127W |
probably damaging |
Het |
| Mrpl48 |
G |
T |
7: 100,195,616 (GRCm39) |
|
probably benign |
Het |
| Ms4a2 |
A |
G |
19: 11,595,793 (GRCm39) |
L166S |
possibly damaging |
Het |
| Mtus2 |
T |
A |
5: 148,013,913 (GRCm39) |
Y235* |
probably null |
Het |
| Myh4 |
G |
T |
11: 67,131,880 (GRCm39) |
W113C |
probably damaging |
Het |
| Nav2 |
T |
A |
7: 49,198,182 (GRCm39) |
C1270* |
probably null |
Het |
| Ncoa5 |
A |
G |
2: 164,844,070 (GRCm39) |
L111P |
probably damaging |
Het |
| Nup107 |
T |
C |
10: 117,606,383 (GRCm39) |
Y453C |
probably damaging |
Het |
| Oca2 |
C |
T |
7: 55,980,106 (GRCm39) |
Q604* |
probably null |
Het |
| Or13a19 |
T |
C |
7: 139,903,014 (GRCm39) |
M134T |
probably benign |
Het |
| Or13p5 |
A |
C |
4: 118,591,885 (GRCm39) |
H53P |
probably benign |
Het |
| Or14j10 |
A |
T |
17: 37,934,782 (GRCm39) |
V248D |
probably damaging |
Het |
| Or5p58 |
T |
A |
7: 107,694,303 (GRCm39) |
N158I |
probably benign |
Het |
| Or8g33 |
T |
C |
9: 39,337,531 (GRCm39) |
T279A |
possibly damaging |
Het |
| Pde3a |
G |
T |
6: 141,416,668 (GRCm39) |
G514V |
possibly damaging |
Het |
| Pik3cb |
A |
T |
9: 98,983,381 (GRCm39) |
C76S |
probably damaging |
Het |
| Plk1 |
T |
C |
7: 121,767,828 (GRCm39) |
V411A |
probably damaging |
Het |
| Pole |
C |
T |
5: 110,472,619 (GRCm39) |
P1600L |
probably damaging |
Het |
| Prr36 |
T |
C |
8: 4,260,881 (GRCm39) |
T979A |
probably benign |
Het |
| Rdh7 |
T |
A |
10: 127,721,590 (GRCm39) |
T229S |
probably benign |
Het |
| Rnpepl1 |
A |
T |
1: 92,842,835 (GRCm39) |
T140S |
probably damaging |
Het |
| Rps6kc1 |
A |
T |
1: 190,530,891 (GRCm39) |
S947T |
probably benign |
Het |
| Rtl1 |
A |
G |
12: 109,558,138 (GRCm39) |
F1234L |
probably damaging |
Het |
| Sdc1 |
G |
A |
12: 8,841,708 (GRCm39) |
M279I |
probably damaging |
Het |
| Siae |
T |
C |
9: 37,539,096 (GRCm39) |
L169P |
possibly damaging |
Het |
| Slc22a22 |
C |
T |
15: 57,113,148 (GRCm39) |
V364I |
probably benign |
Het |
| Sltm |
G |
T |
9: 70,496,260 (GRCm39) |
V932F |
probably damaging |
Het |
| Smad1 |
A |
G |
8: 80,076,381 (GRCm39) |
L279P |
probably damaging |
Het |
| Spag17 |
G |
T |
3: 99,958,147 (GRCm39) |
G935V |
probably damaging |
Het |
| Srgap3 |
A |
G |
6: 112,723,895 (GRCm39) |
S546P |
probably damaging |
Het |
| Stxbp5 |
T |
C |
10: 9,684,844 (GRCm39) |
I519V |
probably benign |
Het |
| Syt16 |
A |
T |
12: 74,176,160 (GRCm39) |
I10F |
probably damaging |
Het |
| Trim43b |
C |
G |
9: 88,973,365 (GRCm39) |
G123R |
probably damaging |
Het |
| Ubr3 |
T |
C |
2: 69,843,475 (GRCm39) |
Y1572H |
probably damaging |
Het |
| Umodl1 |
G |
A |
17: 31,227,639 (GRCm39) |
R1324H |
probably benign |
Het |
| Vmn2r44 |
A |
T |
7: 8,380,985 (GRCm39) |
W303R |
probably benign |
Het |
| Wdr93 |
T |
C |
7: 79,435,522 (GRCm39) |
Y684H |
probably damaging |
Het |
| Wnk2 |
G |
A |
13: 49,224,478 (GRCm39) |
R268C |
probably damaging |
Het |
| Zfp438 |
C |
T |
18: 5,213,776 (GRCm39) |
C394Y |
possibly damaging |
Het |
|
| Other mutations in Ltn1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00328:Ltn1
|
APN |
16 |
87,215,378 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL01139:Ltn1
|
APN |
16 |
87,212,897 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01359:Ltn1
|
APN |
16 |
87,202,581 (GRCm39) |
splice site |
probably benign |
|
|
IGL01503:Ltn1
|
APN |
16 |
87,217,695 (GRCm39) |
critical splice donor site |
probably benign |
|
|
IGL01529:Ltn1
|
APN |
16 |
87,178,359 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02437:Ltn1
|
APN |
16 |
87,194,889 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL02658:Ltn1
|
APN |
16 |
87,212,662 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02890:Ltn1
|
APN |
16 |
87,206,185 (GRCm39) |
splice site |
probably null |
|
|
IGL02899:Ltn1
|
APN |
16 |
87,179,547 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL02902:Ltn1
|
APN |
16 |
87,176,693 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL03128:Ltn1
|
APN |
16 |
87,212,832 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL03392:Ltn1
|
APN |
16 |
87,222,499 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03046:Ltn1
|
UTSW |
16 |
87,202,509 (GRCm39) |
missense |
probably benign |
0.10 |
|
PIT4305001:Ltn1
|
UTSW |
16 |
87,217,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4366001:Ltn1
|
UTSW |
16 |
87,177,728 (GRCm39) |
nonsense |
probably null |
|
|
R0126:Ltn1
|
UTSW |
16 |
87,222,528 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0164:Ltn1
|
UTSW |
16 |
87,202,407 (GRCm39) |
splice site |
probably benign |
|
|
R0165:Ltn1
|
UTSW |
16 |
87,202,407 (GRCm39) |
splice site |
probably benign |
|
|
R0280:Ltn1
|
UTSW |
16 |
87,194,726 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0565:Ltn1
|
UTSW |
16 |
87,212,898 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0733:Ltn1
|
UTSW |
16 |
87,209,395 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1034:Ltn1
|
UTSW |
16 |
87,194,025 (GRCm39) |
splice site |
probably null |
|
|
R1252:Ltn1
|
UTSW |
16 |
87,212,918 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1524:Ltn1
|
UTSW |
16 |
87,178,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1746:Ltn1
|
UTSW |
16 |
87,208,669 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R1826:Ltn1
|
UTSW |
16 |
87,212,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1831:Ltn1
|
UTSW |
16 |
87,197,034 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1839:Ltn1
|
UTSW |
16 |
87,213,152 (GRCm39) |
nonsense |
probably null |
|
|
R1860:Ltn1
|
UTSW |
16 |
87,213,231 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1997:Ltn1
|
UTSW |
16 |
87,178,525 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2109:Ltn1
|
UTSW |
16 |
87,212,530 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2134:Ltn1
|
UTSW |
16 |
87,179,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2135:Ltn1
|
UTSW |
16 |
87,179,601 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2193:Ltn1
|
UTSW |
16 |
87,224,535 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2307:Ltn1
|
UTSW |
16 |
87,229,312 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2376:Ltn1
|
UTSW |
16 |
87,217,695 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3054:Ltn1
|
UTSW |
16 |
87,200,961 (GRCm39) |
missense |
probably benign |
0.32 |
|
R3404:Ltn1
|
UTSW |
16 |
87,213,103 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3405:Ltn1
|
UTSW |
16 |
87,213,103 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3618:Ltn1
|
UTSW |
16 |
87,217,787 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4065:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4066:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4067:Ltn1
|
UTSW |
16 |
87,213,118 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4288:Ltn1
|
UTSW |
16 |
87,194,876 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4436:Ltn1
|
UTSW |
16 |
87,202,502 (GRCm39) |
missense |
probably benign |
0.17 |
|
R4535:Ltn1
|
UTSW |
16 |
87,223,174 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4581:Ltn1
|
UTSW |
16 |
87,198,912 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4669:Ltn1
|
UTSW |
16 |
87,215,375 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R4715:Ltn1
|
UTSW |
16 |
87,215,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4830:Ltn1
|
UTSW |
16 |
87,176,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4961:Ltn1
|
UTSW |
16 |
87,194,679 (GRCm39) |
missense |
probably benign |
|
|
R4992:Ltn1
|
UTSW |
16 |
87,202,475 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R5073:Ltn1
|
UTSW |
16 |
87,224,628 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5288:Ltn1
|
UTSW |
16 |
87,212,899 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5802:Ltn1
|
UTSW |
16 |
87,212,569 (GRCm39) |
missense |
probably benign |
0.17 |
|
R5907:Ltn1
|
UTSW |
16 |
87,178,391 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6180:Ltn1
|
UTSW |
16 |
87,224,677 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6194:Ltn1
|
UTSW |
16 |
87,212,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6257:Ltn1
|
UTSW |
16 |
87,208,662 (GRCm39) |
missense |
possibly damaging |
0.74 |
|
R6301:Ltn1
|
UTSW |
16 |
87,217,194 (GRCm39) |
missense |
probably benign |
|
|
R6481:Ltn1
|
UTSW |
16 |
87,175,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6525:Ltn1
|
UTSW |
16 |
87,217,074 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6958:Ltn1
|
UTSW |
16 |
87,194,679 (GRCm39) |
missense |
probably benign |
|
|
R6969:Ltn1
|
UTSW |
16 |
87,212,578 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7002:Ltn1
|
UTSW |
16 |
87,220,361 (GRCm39) |
missense |
probably benign |
|
|
R7038:Ltn1
|
UTSW |
16 |
87,221,759 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7062:Ltn1
|
UTSW |
16 |
87,224,491 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7152:Ltn1
|
UTSW |
16 |
87,224,529 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7180:Ltn1
|
UTSW |
16 |
87,215,382 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7247:Ltn1
|
UTSW |
16 |
87,206,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7454:Ltn1
|
UTSW |
16 |
87,194,700 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7471:Ltn1
|
UTSW |
16 |
87,194,787 (GRCm39) |
missense |
probably benign |
|
|
R7511:Ltn1
|
UTSW |
16 |
87,205,716 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7691:Ltn1
|
UTSW |
16 |
87,195,574 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7702:Ltn1
|
UTSW |
16 |
87,223,166 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7761:Ltn1
|
UTSW |
16 |
87,208,681 (GRCm39) |
missense |
probably benign |
|
|
R8002:Ltn1
|
UTSW |
16 |
87,212,835 (GRCm39) |
missense |
probably benign |
0.17 |
|
R8101:Ltn1
|
UTSW |
16 |
87,215,385 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8142:Ltn1
|
UTSW |
16 |
87,178,529 (GRCm39) |
missense |
probably benign |
0.21 |
|
R8214:Ltn1
|
UTSW |
16 |
87,177,691 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8674:Ltn1
|
UTSW |
16 |
87,195,673 (GRCm39) |
missense |
probably benign |
|
|
R8783:Ltn1
|
UTSW |
16 |
87,207,247 (GRCm39) |
missense |
probably benign |
0.30 |
|
R8839:Ltn1
|
UTSW |
16 |
87,215,390 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8885:Ltn1
|
UTSW |
16 |
87,178,433 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8889:Ltn1
|
UTSW |
16 |
87,229,230 (GRCm39) |
intron |
probably benign |
|
|
R8892:Ltn1
|
UTSW |
16 |
87,229,230 (GRCm39) |
intron |
probably benign |
|
|
R8919:Ltn1
|
UTSW |
16 |
87,178,381 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8970:Ltn1
|
UTSW |
16 |
87,212,926 (GRCm39) |
missense |
probably benign |
|
|
R9113:Ltn1
|
UTSW |
16 |
87,224,532 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9206:Ltn1
|
UTSW |
16 |
87,197,298 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9208:Ltn1
|
UTSW |
16 |
87,197,298 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9234:Ltn1
|
UTSW |
16 |
87,194,089 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9421:Ltn1
|
UTSW |
16 |
87,215,375 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9558:Ltn1
|
UTSW |
16 |
87,220,295 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9654:Ltn1
|
UTSW |
16 |
87,207,227 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9738:Ltn1
|
UTSW |
16 |
87,222,524 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0028:Ltn1
|
UTSW |
16 |
87,199,022 (GRCm39) |
missense |
probably benign |
0.01 |
|
Z1177:Ltn1
|
UTSW |
16 |
87,198,925 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- AGACTGCCTCTAAGAAAGCAAG -3'
(R):5'- ACTATGGACTAAAACAGCCACTTTC -3'
Sequencing Primer
(F):5'- GTCAACAGCCATTTTCAATAATTACC -3'
(R):5'- GGACTAAAACAGCCACTTTCTTTTC -3'
|
| Posted On |
2016-03-17 |
Incidental Mutation