Incidental Mutation 'R4918:Fan1'
| ID |
378403 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Fan1
|
| Ensembl Gene |
ENSMUSG00000033458 |
| Gene Name |
FANCD2/FANCI-associated nuclease 1 |
| Synonyms |
Mtmr15, 6030441H18Rik |
| MMRRC Submission |
042520-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4918 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
7 |
| Chromosomal Location |
63996506-64023843 bp(-) (GRCm39) |
| Type of Mutation |
utr 5 prime |
| DNA Base Change (assembly) |
A to T
at 64023286 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000130012
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000032735]
[ENSMUST00000163289]
|
| AlphaFold |
Q69ZT1 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000032735
|
| SMART Domains |
Protein: ENSMUSP00000032735
Gene: ENSMUSG00000030521
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Mpp10
|
20 |
654 |
6.9e-217 |
PFAM |
|
low complexity region
|
666 |
671 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000107514
AA Change: I22N
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000123627
AA Change: D126E
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000163289
|
| SMART Domains |
Protein: ENSMUSP00000130012
Gene: ENSMUSG00000033458
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1ihga1
|
600 |
737 |
5e-5 |
SMART |
|
Blast:VRR_NUC
|
834 |
867 |
2e-12 |
BLAST |
|
VRR_NUC
|
896 |
1011 |
1.99e-37 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206047
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206329
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206730
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206778
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.4%
- 20x: 92.7%
|
| Validation Efficiency |
99% (116/117) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene plays a role in DNA interstrand cross-link repair and encodes a protein with 5' flap endonuclease and 5'-3' exonuclease activity. Mutations in this gene cause karyomegalic interstitial nephritis. Alternatively spliced transcript variants encoding distinct isoforms have been described. [provided by RefSeq, Feb 2016]
PHENOTYPE: Mice homozygous for mutations in this gene display renal tubular karyomegaly with polyploidy and defects in interstrand cross-link DNA repair. Some homozygous mice also display hepatocyte karyomegaly and liver dysfunction. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca6 |
T |
A |
11: 110,071,377 (GRCm39) |
I1492F |
probably damaging |
Het |
| Ago4 |
A |
C |
4: 126,400,635 (GRCm39) |
C693G |
probably damaging |
Het |
| Apobec2 |
T |
C |
17: 48,730,153 (GRCm39) |
E171G |
probably benign |
Het |
| Arfgef3 |
T |
A |
10: 18,492,638 (GRCm39) |
I1258F |
probably damaging |
Het |
| Arhgef40 |
A |
G |
14: 52,227,556 (GRCm39) |
E434G |
probably damaging |
Het |
| Baz2b |
T |
A |
2: 59,744,387 (GRCm39) |
T1373S |
possibly damaging |
Het |
| Bcas1 |
T |
C |
2: 170,220,806 (GRCm39) |
D324G |
probably damaging |
Het |
| Bdp1 |
A |
T |
13: 100,191,713 (GRCm39) |
V1422E |
probably damaging |
Het |
| Bfsp1 |
C |
T |
2: 143,669,391 (GRCm39) |
R396Q |
probably benign |
Het |
| Bnip1 |
C |
T |
17: 27,002,525 (GRCm39) |
|
probably benign |
Het |
| Bnip5 |
T |
G |
17: 29,127,337 (GRCm39) |
Q224P |
probably benign |
Het |
| Bpifb9b |
T |
A |
2: 154,156,026 (GRCm39) |
|
probably null |
Het |
| Casp8 |
T |
C |
1: 58,866,377 (GRCm39) |
F126S |
probably damaging |
Het |
| Cdh26 |
T |
C |
2: 178,091,614 (GRCm39) |
S58P |
probably benign |
Het |
| Cntnap2 |
T |
C |
6: 46,506,969 (GRCm39) |
|
probably benign |
Het |
| Col9a1 |
T |
C |
1: 24,276,339 (GRCm39) |
I749T |
possibly damaging |
Het |
| Ddx50 |
A |
T |
10: 62,463,450 (GRCm39) |
C414* |
probably null |
Het |
| Defb42 |
A |
G |
14: 63,285,790 (GRCm39) |
I57V |
probably benign |
Het |
| Dennd5a |
A |
G |
7: 109,500,296 (GRCm39) |
F943S |
probably damaging |
Het |
| Dhx40 |
G |
T |
11: 86,695,217 (GRCm39) |
H98N |
possibly damaging |
Het |
| Disp2 |
A |
T |
2: 118,620,935 (GRCm39) |
S556C |
probably damaging |
Het |
| Dpysl5 |
T |
G |
5: 30,949,612 (GRCm39) |
F461V |
probably damaging |
Het |
| Efcab11 |
T |
C |
12: 99,685,321 (GRCm39) |
D151G |
probably damaging |
Het |
| Egfem1 |
T |
C |
3: 29,206,042 (GRCm39) |
V93A |
probably damaging |
Het |
| Ehbp1 |
T |
C |
11: 22,096,592 (GRCm39) |
D299G |
probably benign |
Het |
| Esyt2 |
T |
C |
12: 116,287,760 (GRCm39) |
V226A |
probably benign |
Het |
| Fasn |
T |
G |
11: 120,707,472 (GRCm39) |
N799T |
probably benign |
Het |
| Fbxo3 |
T |
G |
2: 103,885,311 (GRCm39) |
N388K |
probably damaging |
Het |
| Fer1l4 |
T |
C |
2: 155,873,220 (GRCm39) |
K1287E |
probably benign |
Het |
| Fn1 |
A |
T |
1: 71,634,968 (GRCm39) |
|
probably null |
Het |
| Fsip2 |
G |
A |
2: 82,824,114 (GRCm39) |
V6616I |
possibly damaging |
Het |
| Fut8 |
G |
T |
12: 77,521,818 (GRCm39) |
A486S |
probably damaging |
Het |
| Glp2r |
G |
T |
11: 67,648,419 (GRCm39) |
Y94* |
probably null |
Het |
| Gm10764 |
A |
G |
10: 87,126,579 (GRCm39) |
|
noncoding transcript |
Het |
| Gm6788 |
C |
T |
19: 28,740,664 (GRCm39) |
|
noncoding transcript |
Het |
| Gm8122 |
T |
C |
14: 43,091,573 (GRCm39) |
N65S |
unknown |
Het |
| Golga4 |
C |
A |
9: 118,387,213 (GRCm39) |
S1445Y |
probably damaging |
Het |
| Gsdmd |
A |
G |
15: 75,736,241 (GRCm39) |
I123M |
probably benign |
Het |
| Hsf4 |
A |
G |
8: 105,999,367 (GRCm39) |
E235G |
probably benign |
Het |
| Ifi206 |
T |
A |
1: 173,309,610 (GRCm39) |
T129S |
possibly damaging |
Het |
| Jakmip1 |
G |
A |
5: 37,248,619 (GRCm39) |
R93Q |
probably damaging |
Het |
| Kcnj1 |
T |
A |
9: 32,308,056 (GRCm39) |
L160Q |
probably damaging |
Het |
| Kif1a |
T |
A |
1: 93,002,700 (GRCm39) |
E233V |
probably benign |
Het |
| Krt5 |
A |
T |
15: 101,618,742 (GRCm39) |
Y340N |
probably damaging |
Het |
| Krt90 |
T |
A |
15: 101,470,914 (GRCm39) |
H116L |
possibly damaging |
Het |
| Large2 |
A |
G |
2: 92,196,452 (GRCm39) |
|
probably benign |
Het |
| Marchf4 |
T |
G |
1: 72,467,938 (GRCm39) |
S365R |
probably benign |
Het |
| Mei4 |
A |
G |
9: 81,772,216 (GRCm39) |
T10A |
probably benign |
Het |
| Meis1 |
T |
C |
11: 18,959,222 (GRCm39) |
|
probably benign |
Het |
| Mllt1 |
T |
C |
17: 57,206,813 (GRCm39) |
T344A |
probably benign |
Het |
| Mrps28 |
A |
G |
3: 8,947,614 (GRCm39) |
|
probably benign |
Het |
| Ncdn |
G |
A |
4: 126,643,731 (GRCm39) |
L364F |
possibly damaging |
Het |
| Nckap1l |
A |
G |
15: 103,392,040 (GRCm39) |
N825S |
probably benign |
Het |
| Nfat5 |
T |
A |
8: 108,051,284 (GRCm39) |
D47E |
probably damaging |
Het |
| Nfix |
T |
C |
8: 85,498,458 (GRCm39) |
I172V |
probably benign |
Het |
| Nkx3-1 |
G |
A |
14: 69,428,367 (GRCm39) |
G72S |
probably benign |
Het |
| Nsf |
G |
A |
11: 103,801,185 (GRCm39) |
|
probably benign |
Het |
| Or1b1 |
A |
T |
2: 36,995,170 (GRCm39) |
I164N |
possibly damaging |
Het |
| Or1n1b |
A |
G |
2: 36,780,344 (GRCm39) |
I172T |
probably damaging |
Het |
| Or3a1b |
A |
T |
11: 74,012,705 (GRCm39) |
I197F |
probably benign |
Het |
| Or51g2 |
A |
T |
7: 102,622,614 (GRCm39) |
I195N |
possibly damaging |
Het |
| Or5ak20 |
C |
T |
2: 85,183,632 (GRCm39) |
V213I |
probably benign |
Het |
| Or5b106 |
T |
A |
19: 13,123,355 (GRCm39) |
I223L |
possibly damaging |
Het |
| Or5bw2 |
C |
T |
7: 6,573,643 (GRCm39) |
L218F |
possibly damaging |
Het |
| Or9g10 |
T |
C |
2: 85,584,465 (GRCm39) |
|
probably benign |
Het |
| Pcdh20 |
A |
C |
14: 88,705,104 (GRCm39) |
L732R |
probably damaging |
Het |
| Pgbd5 |
C |
A |
8: 125,097,305 (GRCm39) |
K408N |
probably benign |
Het |
| Pip4k2c |
T |
C |
10: 127,035,196 (GRCm39) |
T391A |
possibly damaging |
Het |
| Ppm1k |
T |
A |
6: 57,487,762 (GRCm39) |
N354Y |
probably damaging |
Het |
| Prpf18 |
T |
C |
2: 4,641,981 (GRCm39) |
D186G |
probably benign |
Het |
| Rab3gap1 |
T |
A |
1: 127,816,914 (GRCm39) |
W58R |
possibly damaging |
Het |
| Rbp3 |
T |
C |
14: 33,677,368 (GRCm39) |
Y439H |
probably damaging |
Het |
| Rere |
T |
A |
4: 150,703,601 (GRCm39) |
W1528R |
probably damaging |
Het |
| Rsf1 |
T |
C |
7: 97,311,612 (GRCm39) |
S781P |
probably damaging |
Het |
| Rufy4 |
T |
C |
1: 74,186,822 (GRCm39) |
C537R |
probably damaging |
Het |
| Ryr2 |
A |
G |
13: 11,609,872 (GRCm39) |
V753A |
probably damaging |
Het |
| Schip1 |
A |
T |
3: 68,315,818 (GRCm39) |
|
probably benign |
Het |
| Scin |
T |
A |
12: 40,119,373 (GRCm39) |
I552F |
possibly damaging |
Het |
| Scn3a |
T |
C |
2: 65,291,799 (GRCm39) |
N1649S |
probably damaging |
Het |
| Sh3rf3 |
A |
T |
10: 58,842,925 (GRCm39) |
D297V |
probably damaging |
Het |
| Slc20a2 |
C |
T |
8: 23,051,020 (GRCm39) |
S351L |
probably damaging |
Het |
| Slc35e2 |
C |
A |
4: 155,700,693 (GRCm39) |
P272Q |
probably damaging |
Het |
| Slc4a1 |
A |
G |
11: 102,243,279 (GRCm39) |
V784A |
probably damaging |
Het |
| Slco1b2 |
G |
A |
6: 141,615,096 (GRCm39) |
V334I |
probably benign |
Het |
| Slf2 |
T |
G |
19: 44,960,100 (GRCm39) |
D1022E |
probably damaging |
Het |
| Spag6 |
A |
T |
2: 18,750,360 (GRCm39) |
I469F |
probably benign |
Het |
| Spsb2 |
A |
C |
6: 124,786,711 (GRCm39) |
E148A |
probably benign |
Het |
| Sulf1 |
A |
G |
1: 12,888,720 (GRCm39) |
D335G |
probably damaging |
Het |
| Tchhl1 |
A |
G |
3: 93,377,623 (GRCm39) |
D109G |
possibly damaging |
Het |
| Thoc7 |
T |
C |
14: 13,953,154 (GRCm38) |
I83V |
probably damaging |
Het |
| Thsd7a |
A |
C |
6: 12,327,558 (GRCm39) |
I1438S |
probably damaging |
Het |
| Tm4sf1 |
C |
T |
3: 57,200,448 (GRCm39) |
G85S |
probably damaging |
Het |
| Tmem63a |
T |
A |
1: 180,794,086 (GRCm39) |
I541N |
probably benign |
Het |
| Trav6d-4 |
T |
C |
14: 52,991,240 (GRCm39) |
F95S |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,641,587 (GRCm39) |
L5176Q |
possibly damaging |
Het |
| Ttn |
T |
C |
2: 76,589,598 (GRCm39) |
T21219A |
probably damaging |
Het |
| Unc80 |
T |
C |
1: 66,685,709 (GRCm39) |
Y2278H |
possibly damaging |
Het |
| Usp8 |
A |
T |
2: 126,562,060 (GRCm39) |
K85* |
probably null |
Het |
| Vmn2r69 |
T |
A |
7: 85,055,967 (GRCm39) |
M724L |
probably benign |
Het |
| Zeb2 |
A |
G |
2: 44,886,894 (GRCm39) |
I706T |
probably damaging |
Het |
| Zfp512 |
T |
C |
5: 31,634,209 (GRCm39) |
S407P |
probably damaging |
Het |
| Zfp791 |
T |
A |
8: 85,837,580 (GRCm39) |
I95L |
probably benign |
Het |
|
| Other mutations in Fan1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01648:Fan1
|
APN |
7 |
64,022,297 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL01752:Fan1
|
APN |
7 |
64,022,542 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01971:Fan1
|
APN |
7 |
64,003,459 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02043:Fan1
|
APN |
7 |
64,021,367 (GRCm39) |
splice site |
probably null |
|
|
IGL02542:Fan1
|
APN |
7 |
64,014,408 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02731:Fan1
|
APN |
7 |
64,022,741 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
IGL03111:Fan1
|
APN |
7 |
63,999,816 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
hitched
|
UTSW |
7 |
64,014,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
stitched
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0270:Fan1
|
UTSW |
7 |
63,998,619 (GRCm39) |
missense |
probably benign |
0.26 |
|
R0632:Fan1
|
UTSW |
7 |
64,012,947 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R1714:Fan1
|
UTSW |
7 |
64,016,435 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1750:Fan1
|
UTSW |
7 |
64,022,761 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1822:Fan1
|
UTSW |
7 |
64,022,554 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2031:Fan1
|
UTSW |
7 |
64,004,172 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2107:Fan1
|
UTSW |
7 |
64,016,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2126:Fan1
|
UTSW |
7 |
63,996,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2869:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2869:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2870:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2870:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2871:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2871:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R2873:Fan1
|
UTSW |
7 |
64,012,938 (GRCm39) |
missense |
probably benign |
0.16 |
|
R3849:Fan1
|
UTSW |
7 |
64,022,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3850:Fan1
|
UTSW |
7 |
64,022,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3949:Fan1
|
UTSW |
7 |
64,021,292 (GRCm39) |
nonsense |
probably null |
|
|
R4007:Fan1
|
UTSW |
7 |
64,016,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4490:Fan1
|
UTSW |
7 |
64,018,928 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R4623:Fan1
|
UTSW |
7 |
64,023,301 (GRCm39) |
nonsense |
probably null |
|
|
R5328:Fan1
|
UTSW |
7 |
64,004,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5691:Fan1
|
UTSW |
7 |
64,004,118 (GRCm39) |
splice site |
probably null |
|
|
R5902:Fan1
|
UTSW |
7 |
64,023,070 (GRCm39) |
splice site |
probably null |
|
|
R5905:Fan1
|
UTSW |
7 |
64,003,399 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6126:Fan1
|
UTSW |
7 |
64,014,318 (GRCm39) |
nonsense |
probably null |
|
|
R6195:Fan1
|
UTSW |
7 |
64,004,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6233:Fan1
|
UTSW |
7 |
64,004,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6405:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6434:Fan1
|
UTSW |
7 |
64,004,129 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6460:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6469:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6471:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6473:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6696:Fan1
|
UTSW |
7 |
63,999,826 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6708:Fan1
|
UTSW |
7 |
64,022,554 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6713:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6714:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6749:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6841:Fan1
|
UTSW |
7 |
64,014,377 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6858:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6859:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6860:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6925:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6927:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6936:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6938:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R6939:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7040:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7120:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7290:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7292:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7459:Fan1
|
UTSW |
7 |
63,998,714 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7460:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7464:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7465:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7465:Fan1
|
UTSW |
7 |
64,003,386 (GRCm39) |
missense |
probably benign |
0.30 |
|
R7608:Fan1
|
UTSW |
7 |
64,003,979 (GRCm39) |
splice site |
probably null |
|
|
R7624:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7629:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7682:Fan1
|
UTSW |
7 |
64,022,512 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7731:Fan1
|
UTSW |
7 |
64,022,444 (GRCm39) |
missense |
probably benign |
0.17 |
|
R7863:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8054:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8055:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8057:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8058:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8101:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8241:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8262:Fan1
|
UTSW |
7 |
64,023,054 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8274:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8275:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8276:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8285:Fan1
|
UTSW |
7 |
64,016,348 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8318:Fan1
|
UTSW |
7 |
63,999,803 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8402:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8466:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8468:Fan1
|
UTSW |
7 |
64,022,234 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8799:Fan1
|
UTSW |
7 |
64,016,406 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8821:Fan1
|
UTSW |
7 |
64,004,249 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9030:Fan1
|
UTSW |
7 |
64,022,761 (GRCm39) |
missense |
probably benign |
0.14 |
|
R9181:Fan1
|
UTSW |
7 |
64,016,400 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9525:Fan1
|
UTSW |
7 |
64,022,007 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9564:Fan1
|
UTSW |
7 |
63,999,240 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9565:Fan1
|
UTSW |
7 |
63,999,240 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R9796:Fan1
|
UTSW |
7 |
64,022,278 (GRCm39) |
missense |
probably benign |
0.09 |
|
X0025:Fan1
|
UTSW |
7 |
64,022,583 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTCATCAAGGTGCCGAATGAG -3'
(R):5'- CACTTTGTATTAGTTCACGGCG -3'
Sequencing Primer
(F):5'- GTGCCGAATGAGGTCATACC -3'
(R):5'- CGGCGAGAGTAAAAGTAACCCTTTAG -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation