Incidental Mutation 'R4908:Nckap5'
| ID |
379152 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nckap5
|
| Ensembl Gene |
ENSMUSG00000049690 |
| Gene Name |
NCK-associated protein 5 |
| Synonyms |
LOC380609, D130011D22Rik, E030049G20Rik |
| MMRRC Submission |
042510-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4908 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
1 |
| Chromosomal Location |
125841373-126758529 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 125955324 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Arginine
at position 477
(S477R)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000108202
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000057846]
[ENSMUST00000094609]
[ENSMUST00000094610]
[ENSMUST00000112583]
[ENSMUST00000161954]
[ENSMUST00000162877]
|
| AlphaFold |
E9QAE1 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000057846
AA Change: S345R
PolyPhen 2
Score 0.988 (Sensitivity: 0.73; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000062229
Gene: ENSMUSG00000049690
AA Change: S345R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
321 |
332 |
N/A |
INTRINSIC |
|
low complexity region
|
755 |
771 |
N/A |
INTRINSIC |
|
low complexity region
|
950 |
971 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1085 |
N/A |
INTRINSIC |
|
low complexity region
|
1181 |
1200 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1298 |
1602 |
1.8e-120 |
PFAM |
|
low complexity region
|
1728 |
1742 |
N/A |
INTRINSIC |
|
low complexity region
|
1757 |
1771 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094609
|
| SMART Domains |
Protein: ENSMUSP00000092192
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
113 |
364 |
3.6e-36 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000094610
|
| SMART Domains |
Protein: ENSMUSP00000092193
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
1 |
101 |
8.8e-42 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112583
AA Change: S477R
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108202
Gene: ENSMUSG00000049690
AA Change: S477R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
70 |
93 |
N/A |
INTRINSIC |
|
coiled coil region
|
176 |
254 |
N/A |
INTRINSIC |
|
low complexity region
|
301 |
324 |
N/A |
INTRINSIC |
|
low complexity region
|
453 |
464 |
N/A |
INTRINSIC |
|
low complexity region
|
887 |
903 |
N/A |
INTRINSIC |
|
low complexity region
|
1082 |
1103 |
N/A |
INTRINSIC |
|
low complexity region
|
1202 |
1217 |
N/A |
INTRINSIC |
|
low complexity region
|
1313 |
1332 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1431 |
1733 |
5.3e-119 |
PFAM |
|
low complexity region
|
1860 |
1874 |
N/A |
INTRINSIC |
|
low complexity region
|
1889 |
1903 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000159934
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000161954
AA Change: S409R
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000125624
Gene: ENSMUSG00000049690
AA Change: S409R
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
25 |
N/A |
INTRINSIC |
|
coiled coil region
|
108 |
186 |
N/A |
INTRINSIC |
|
low complexity region
|
233 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
385 |
396 |
N/A |
INTRINSIC |
|
low complexity region
|
819 |
835 |
N/A |
INTRINSIC |
|
low complexity region
|
1014 |
1035 |
N/A |
INTRINSIC |
|
low complexity region
|
1134 |
1149 |
N/A |
INTRINSIC |
|
low complexity region
|
1245 |
1264 |
N/A |
INTRINSIC |
|
Pfam:NCKAP5
|
1362 |
1666 |
2.1e-120 |
PFAM |
|
low complexity region
|
1792 |
1806 |
N/A |
INTRINSIC |
|
low complexity region
|
1821 |
1835 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000162877
|
| SMART Domains |
Protein: ENSMUSP00000124748
Gene: ENSMUSG00000049690
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NCKAP5
|
9 |
296 |
6e-36 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.2%
- 20x: 92.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
All alleles(1) : Gene trapped(1) |
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110059G10Rik |
T |
A |
9: 122,778,008 (GRCm39) |
I79L |
probably benign |
Het |
| Ablim2 |
C |
T |
5: 35,959,766 (GRCm39) |
R73C |
possibly damaging |
Het |
| Acaa1a |
G |
A |
9: 119,177,772 (GRCm39) |
S218N |
probably benign |
Het |
| Acsm5 |
A |
T |
7: 119,137,314 (GRCm39) |
I377F |
probably damaging |
Het |
| Ahnak2 |
T |
C |
12: 112,741,706 (GRCm39) |
T789A |
probably benign |
Het |
| Ak9 |
A |
T |
10: 41,296,678 (GRCm39) |
T1475S |
unknown |
Het |
| AU040320 |
A |
T |
4: 126,747,081 (GRCm39) |
N1028Y |
probably damaging |
Het |
| Bahcc1 |
T |
A |
11: 120,178,580 (GRCm39) |
S2380T |
probably benign |
Het |
| Cadps |
A |
G |
14: 12,536,386 (GRCm38) |
Y525H |
probably damaging |
Het |
| Casp8ap2 |
A |
G |
4: 32,639,905 (GRCm39) |
T320A |
possibly damaging |
Het |
| Ccdc138 |
A |
G |
10: 58,380,817 (GRCm39) |
N483D |
possibly damaging |
Het |
| Ccdc39 |
G |
A |
3: 33,893,242 (GRCm39) |
|
probably null |
Het |
| Cd300c2 |
T |
C |
11: 114,887,772 (GRCm39) |
N210S |
probably damaging |
Het |
| Cd84 |
A |
G |
1: 171,700,432 (GRCm39) |
D183G |
probably damaging |
Het |
| Cep95 |
C |
T |
11: 106,702,172 (GRCm39) |
P390S |
probably damaging |
Het |
| Chd9 |
A |
T |
8: 91,741,877 (GRCm39) |
H1622L |
possibly damaging |
Het |
| Cilp |
C |
A |
9: 65,185,302 (GRCm39) |
Q466K |
probably benign |
Het |
| Cinp |
T |
A |
12: 110,850,487 (GRCm39) |
T5S |
probably damaging |
Het |
| Clec4a2 |
T |
C |
6: 123,119,462 (GRCm39) |
L238S |
probably damaging |
Het |
| Cntrob |
T |
C |
11: 69,211,732 (GRCm39) |
Y164C |
probably damaging |
Het |
| Col6a3 |
A |
G |
1: 90,735,246 (GRCm39) |
L1408P |
probably damaging |
Het |
| Cul3 |
G |
A |
1: 80,258,632 (GRCm39) |
S468L |
possibly damaging |
Het |
| Dnah11 |
T |
A |
12: 118,090,618 (GRCm39) |
D1081V |
probably benign |
Het |
| Dnah2 |
C |
A |
11: 69,411,973 (GRCm39) |
V263L |
probably benign |
Het |
| Efna3 |
C |
G |
3: 89,222,805 (GRCm39) |
R185P |
probably damaging |
Het |
| F5 |
A |
T |
1: 164,039,389 (GRCm39) |
I2000F |
probably damaging |
Het |
| Fancm |
G |
A |
12: 65,141,645 (GRCm39) |
G422E |
probably benign |
Het |
| Gcnt2 |
A |
T |
13: 41,014,210 (GRCm39) |
D127V |
probably damaging |
Het |
| Gm21798 |
G |
T |
15: 64,689,618 (GRCm39) |
|
probably benign |
Het |
| Gramd1a |
A |
C |
7: 30,838,292 (GRCm39) |
S320R |
probably benign |
Het |
| Grn |
T |
C |
11: 102,327,344 (GRCm39) |
|
probably benign |
Het |
| Helq |
A |
T |
5: 100,910,507 (GRCm39) |
|
probably null |
Het |
| Herc2 |
A |
G |
7: 55,827,660 (GRCm39) |
I2914V |
probably benign |
Het |
| Hnrnph1 |
T |
C |
11: 50,269,237 (GRCm39) |
V27A |
probably damaging |
Het |
| Hs1bp3 |
G |
T |
12: 8,374,007 (GRCm39) |
G182C |
probably damaging |
Het |
| Idnk |
C |
T |
13: 58,311,267 (GRCm39) |
P78L |
probably benign |
Het |
| Il10ra |
T |
C |
9: 45,166,919 (GRCm39) |
D544G |
probably benign |
Het |
| Inpp5e |
T |
C |
2: 26,290,918 (GRCm39) |
D383G |
probably damaging |
Het |
| Jak1 |
A |
T |
4: 101,036,911 (GRCm39) |
V243D |
probably damaging |
Het |
| Kcnma1 |
A |
T |
14: 23,359,220 (GRCm39) |
S1036T |
probably damaging |
Het |
| Kif26a |
G |
A |
12: 112,123,776 (GRCm39) |
C127Y |
probably damaging |
Het |
| Kif2c |
T |
C |
4: 117,023,608 (GRCm39) |
E368G |
probably damaging |
Het |
| Lasp1 |
T |
A |
11: 97,724,530 (GRCm39) |
|
probably null |
Het |
| Lcor |
T |
A |
19: 41,572,601 (GRCm39) |
V452D |
probably benign |
Het |
| Lrrtm1 |
C |
G |
6: 77,221,661 (GRCm39) |
H373D |
probably benign |
Het |
| Matr3 |
T |
A |
18: 35,705,754 (GRCm39) |
D226E |
probably damaging |
Het |
| Mmp17 |
G |
A |
5: 129,682,730 (GRCm39) |
W456* |
probably null |
Het |
| Mpp4 |
T |
C |
1: 59,164,748 (GRCm39) |
E463G |
probably damaging |
Het |
| Myh6 |
A |
C |
14: 55,194,419 (GRCm39) |
F737V |
probably damaging |
Het |
| Nars2 |
T |
A |
7: 96,672,948 (GRCm39) |
D271E |
probably benign |
Het |
| Nav2 |
A |
G |
7: 49,254,258 (GRCm39) |
E2352G |
probably damaging |
Het |
| Nckap1 |
A |
G |
2: 80,353,718 (GRCm39) |
|
probably null |
Het |
| Nek11 |
T |
G |
9: 105,175,488 (GRCm39) |
I319L |
probably benign |
Het |
| Neto2 |
A |
G |
8: 86,396,393 (GRCm39) |
I84T |
probably damaging |
Het |
| Nlrp9a |
A |
T |
7: 26,250,369 (GRCm39) |
I45F |
probably damaging |
Het |
| Numa1 |
G |
A |
7: 101,662,012 (GRCm39) |
R548H |
probably damaging |
Het |
| Or10a5 |
A |
C |
7: 106,635,364 (GRCm39) |
M1L |
probably benign |
Het |
| Or14c39 |
A |
C |
7: 86,344,395 (GRCm39) |
I244L |
probably benign |
Het |
| Or2ag1b |
A |
T |
7: 106,288,740 (GRCm39) |
L66H |
probably damaging |
Het |
| Or4c10 |
A |
T |
2: 89,760,923 (GRCm39) |
M257L |
probably benign |
Het |
| Or4c100 |
T |
A |
2: 88,356,254 (GRCm39) |
I109N |
probably damaging |
Het |
| Or4k36 |
T |
A |
2: 111,146,574 (GRCm39) |
F250Y |
probably benign |
Het |
| Or7g25 |
A |
G |
9: 19,160,149 (GRCm39) |
V182A |
probably benign |
Het |
| Or9m1 |
A |
T |
2: 87,733,533 (GRCm39) |
N162K |
probably damaging |
Het |
| Pcdhb16 |
T |
A |
18: 37,612,894 (GRCm39) |
|
probably null |
Het |
| Pdcd10 |
T |
C |
3: 75,448,553 (GRCm39) |
T4A |
probably damaging |
Het |
| Pgc |
A |
T |
17: 48,039,819 (GRCm39) |
Y71F |
probably damaging |
Het |
| Phlpp1 |
G |
A |
1: 106,317,481 (GRCm39) |
G1234E |
probably damaging |
Het |
| Prr27 |
T |
C |
5: 87,990,888 (GRCm39) |
F167L |
probably benign |
Het |
| Prrc2b |
T |
A |
2: 32,116,330 (GRCm39) |
S1421T |
possibly damaging |
Het |
| Pxmp2 |
A |
G |
5: 110,431,518 (GRCm39) |
V75A |
probably benign |
Het |
| Pygl |
A |
T |
12: 70,243,807 (GRCm39) |
M545K |
probably null |
Het |
| Ranbp9 |
A |
G |
13: 43,574,733 (GRCm39) |
Y412H |
possibly damaging |
Het |
| Rcc1 |
A |
G |
4: 132,065,064 (GRCm39) |
V140A |
probably damaging |
Het |
| Reln |
A |
G |
5: 22,184,718 (GRCm39) |
V1599A |
probably benign |
Het |
| Rhebl1 |
A |
T |
15: 98,776,903 (GRCm39) |
D122E |
probably damaging |
Het |
| Rock2 |
C |
T |
12: 17,009,492 (GRCm39) |
L676F |
probably benign |
Het |
| Scn9a |
A |
T |
2: 66,357,087 (GRCm39) |
D1062E |
probably benign |
Het |
| Sec63 |
T |
C |
10: 42,681,186 (GRCm39) |
I390T |
probably damaging |
Het |
| Slc10a6 |
T |
C |
5: 103,754,493 (GRCm39) |
E346G |
probably benign |
Het |
| Slc12a3 |
G |
A |
8: 95,075,216 (GRCm39) |
V737M |
possibly damaging |
Het |
| Slc12a8 |
T |
C |
16: 33,426,629 (GRCm39) |
|
probably null |
Het |
| Slc25a38 |
T |
A |
9: 119,949,354 (GRCm39) |
I102N |
probably damaging |
Het |
| Spg7 |
T |
A |
8: 123,807,394 (GRCm39) |
V390E |
probably damaging |
Het |
| Tbc1d20 |
T |
C |
2: 152,144,228 (GRCm39) |
V75A |
probably benign |
Het |
| Tesk1 |
T |
A |
4: 43,445,555 (GRCm39) |
C243* |
probably null |
Het |
| Ttk |
T |
A |
9: 83,725,739 (GRCm39) |
N220K |
possibly damaging |
Het |
| Ttll5 |
A |
G |
12: 85,965,948 (GRCm39) |
E651G |
probably benign |
Het |
| Tubd1 |
T |
C |
11: 86,457,879 (GRCm39) |
Y426H |
probably damaging |
Het |
| Uba6 |
T |
C |
5: 86,288,293 (GRCm39) |
|
silent |
Het |
| Ube2ql1 |
G |
A |
13: 69,852,289 (GRCm39) |
R263W |
probably damaging |
Het |
| Vmn2r117 |
C |
T |
17: 23,678,812 (GRCm39) |
G804D |
probably damaging |
Het |
| Vmn2r25 |
C |
T |
6: 123,805,406 (GRCm39) |
E484K |
probably benign |
Het |
| Vmn2r4 |
T |
A |
3: 64,296,476 (GRCm39) |
I770F |
possibly damaging |
Het |
| Vmn2r82 |
G |
A |
10: 79,214,589 (GRCm39) |
V191M |
probably benign |
Het |
| Zbtb45 |
C |
T |
7: 12,742,037 (GRCm39) |
V74M |
probably damaging |
Het |
| Zfp366 |
T |
C |
13: 99,370,609 (GRCm39) |
V443A |
possibly damaging |
Het |
| Zfyve1 |
A |
T |
12: 83,598,345 (GRCm39) |
C628S |
probably damaging |
Het |
| Zfyve26 |
A |
T |
12: 79,296,469 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Nckap5 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00833:Nckap5
|
APN |
1 |
125,954,889 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL00956:Nckap5
|
APN |
1 |
125,952,755 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01414:Nckap5
|
APN |
1 |
126,456,450 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01482:Nckap5
|
APN |
1 |
125,950,897 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01508:Nckap5
|
APN |
1 |
125,953,309 (GRCm39) |
missense |
probably damaging |
0.96 |
|
IGL02071:Nckap5
|
APN |
1 |
125,909,305 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL02129:Nckap5
|
APN |
1 |
125,955,432 (GRCm39) |
nonsense |
probably null |
|
|
IGL02821:Nckap5
|
APN |
1 |
125,955,553 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03174:Nckap5
|
APN |
1 |
125,909,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
F5493:Nckap5
|
UTSW |
1 |
125,953,564 (GRCm39) |
missense |
probably benign |
|
|
G5030:Nckap5
|
UTSW |
1 |
125,953,591 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0033:Nckap5
|
UTSW |
1 |
125,867,979 (GRCm39) |
intron |
probably benign |
|
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0164:Nckap5
|
UTSW |
1 |
125,952,144 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R0349:Nckap5
|
UTSW |
1 |
125,954,171 (GRCm39) |
missense |
probably benign |
|
|
R0482:Nckap5
|
UTSW |
1 |
125,954,102 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0508:Nckap5
|
UTSW |
1 |
125,909,121 (GRCm39) |
splice site |
probably null |
|
|
R0541:Nckap5
|
UTSW |
1 |
126,623,459 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R0609:Nckap5
|
UTSW |
1 |
125,955,025 (GRCm39) |
nonsense |
probably null |
|
|
R0701:Nckap5
|
UTSW |
1 |
125,953,094 (GRCm39) |
missense |
probably benign |
0.06 |
|
R0782:Nckap5
|
UTSW |
1 |
125,909,278 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1389:Nckap5
|
UTSW |
1 |
125,954,447 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1401:Nckap5
|
UTSW |
1 |
125,942,398 (GRCm39) |
splice site |
probably benign |
|
|
R1436:Nckap5
|
UTSW |
1 |
125,953,798 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R1506:Nckap5
|
UTSW |
1 |
125,953,650 (GRCm39) |
nonsense |
probably null |
|
|
R1528:Nckap5
|
UTSW |
1 |
125,952,659 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R1942:Nckap5
|
UTSW |
1 |
125,952,039 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1968:Nckap5
|
UTSW |
1 |
125,942,367 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2055:Nckap5
|
UTSW |
1 |
125,954,635 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2105:Nckap5
|
UTSW |
1 |
125,954,255 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2214:Nckap5
|
UTSW |
1 |
125,953,487 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R2311:Nckap5
|
UTSW |
1 |
126,456,489 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2403:Nckap5
|
UTSW |
1 |
125,955,146 (GRCm39) |
missense |
probably benign |
0.18 |
|
R2430:Nckap5
|
UTSW |
1 |
125,842,494 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2914:Nckap5
|
UTSW |
1 |
125,954,274 (GRCm39) |
splice site |
probably null |
|
|
R3782:Nckap5
|
UTSW |
1 |
125,952,811 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4133:Nckap5
|
UTSW |
1 |
126,150,443 (GRCm39) |
missense |
probably benign |
0.13 |
|
R4249:Nckap5
|
UTSW |
1 |
125,955,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4448:Nckap5
|
UTSW |
1 |
125,953,463 (GRCm39) |
nonsense |
probably null |
|
|
R4456:Nckap5
|
UTSW |
1 |
125,842,472 (GRCm39) |
unclassified |
probably benign |
|
|
R4682:Nckap5
|
UTSW |
1 |
126,030,279 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4817:Nckap5
|
UTSW |
1 |
125,954,952 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R4907:Nckap5
|
UTSW |
1 |
125,953,889 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4924:Nckap5
|
UTSW |
1 |
125,954,765 (GRCm39) |
nonsense |
probably null |
|
|
R4926:Nckap5
|
UTSW |
1 |
126,456,378 (GRCm39) |
intron |
probably benign |
|
|
R5032:Nckap5
|
UTSW |
1 |
125,904,786 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R5133:Nckap5
|
UTSW |
1 |
125,961,697 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5197:Nckap5
|
UTSW |
1 |
126,150,410 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5238:Nckap5
|
UTSW |
1 |
125,955,461 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5257:Nckap5
|
UTSW |
1 |
125,952,245 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5277:Nckap5
|
UTSW |
1 |
125,954,277 (GRCm39) |
nonsense |
probably null |
|
|
R5512:Nckap5
|
UTSW |
1 |
125,955,481 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5700:Nckap5
|
UTSW |
1 |
125,904,662 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5789:Nckap5
|
UTSW |
1 |
125,955,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6029:Nckap5
|
UTSW |
1 |
125,953,523 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6249:Nckap5
|
UTSW |
1 |
125,952,667 (GRCm39) |
missense |
probably benign |
|
|
R6292:Nckap5
|
UTSW |
1 |
125,842,752 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6521:Nckap5
|
UTSW |
1 |
126,309,909 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6875:Nckap5
|
UTSW |
1 |
125,950,931 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7017:Nckap5
|
UTSW |
1 |
126,030,398 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7018:Nckap5
|
UTSW |
1 |
125,952,785 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7054:Nckap5
|
UTSW |
1 |
126,186,449 (GRCm39) |
splice site |
probably null |
|
|
R7204:Nckap5
|
UTSW |
1 |
125,954,104 (GRCm39) |
missense |
probably benign |
|
|
R7336:Nckap5
|
UTSW |
1 |
125,953,786 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7544:Nckap5
|
UTSW |
1 |
125,953,948 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7590:Nckap5
|
UTSW |
1 |
125,954,270 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7684:Nckap5
|
UTSW |
1 |
125,954,594 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7749:Nckap5
|
UTSW |
1 |
125,952,383 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7773:Nckap5
|
UTSW |
1 |
125,954,581 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7813:Nckap5
|
UTSW |
1 |
125,953,163 (GRCm39) |
missense |
probably benign |
0.10 |
|
R7970:Nckap5
|
UTSW |
1 |
125,952,758 (GRCm39) |
nonsense |
probably null |
|
|
R7992:Nckap5
|
UTSW |
1 |
125,954,547 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8278:Nckap5
|
UTSW |
1 |
125,955,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8373:Nckap5
|
UTSW |
1 |
125,954,032 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8414:Nckap5
|
UTSW |
1 |
125,942,357 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8755:Nckap5
|
UTSW |
1 |
125,954,279 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R9016:Nckap5
|
UTSW |
1 |
126,623,491 (GRCm39) |
start codon destroyed |
probably null |
0.01 |
|
R9209:Nckap5
|
UTSW |
1 |
125,867,928 (GRCm39) |
missense |
unknown |
|
|
R9214:Nckap5
|
UTSW |
1 |
125,942,376 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9300:Nckap5
|
UTSW |
1 |
125,909,423 (GRCm39) |
nonsense |
probably null |
|
|
R9464:Nckap5
|
UTSW |
1 |
125,952,494 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9572:Nckap5
|
UTSW |
1 |
125,955,454 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9721:Nckap5
|
UTSW |
1 |
125,955,017 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9748:Nckap5
|
UTSW |
1 |
125,953,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Nckap5
|
UTSW |
1 |
125,952,569 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1176:Nckap5
|
UTSW |
1 |
126,456,418 (GRCm39) |
critical splice donor site |
probably null |
|
|
Z1177:Nckap5
|
UTSW |
1 |
126,150,396 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CCATGAACTTGGCTGTGTGG -3'
(R):5'- CTATTCGCCAGGAATTAAAACCAGC -3'
Sequencing Primer
(F):5'- AACTTGGCTGTGTGGGTCCC -3'
(R):5'- AGCAGCCTCAAGGAGTGTC -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation