Incidental Mutation 'R4908:Nlrp9a'
| ID |
379190 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nlrp9a
|
| Ensembl Gene |
ENSMUSG00000054102 |
| Gene Name |
NLR family, pyrin domain containing 9A |
| Synonyms |
Nalp9a, Nalp-theta, D7Ertd565e |
| MMRRC Submission |
042510-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.070)
|
| Stock # |
R4908 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
7 |
| Chromosomal Location |
26234448-26273573 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 26250369 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Isoleucine to Phenylalanine
at position 45
(I45F)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000113318
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000071780]
[ENSMUST00000108387]
[ENSMUST00000117252]
[ENSMUST00000122040]
[ENSMUST00000153452]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000071780
AA Change: I45F
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000071685
Gene: ENSMUSG00000054102
AA Change: I45F
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000108387
AA Change: I45F
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000104024
Gene: ENSMUSG00000054102
AA Change: I45F
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
7.7e-33 |
PFAM |
|
LRR
|
631 |
658 |
1.42e0 |
SMART |
|
LRR
|
692 |
719 |
1.42e0 |
SMART |
|
LRR
|
748 |
775 |
2.32e-1 |
SMART |
|
LRR
|
777 |
804 |
3e0 |
SMART |
|
LRR
|
805 |
832 |
1.12e-3 |
SMART |
|
LRR
|
834 |
861 |
2.17e0 |
SMART |
|
LRR
|
862 |
889 |
2.27e-4 |
SMART |
|
LRR
|
891 |
918 |
2.02e2 |
SMART |
|
LRR
|
919 |
946 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000117252
AA Change: I45F
PolyPhen 2
Score 0.978 (Sensitivity: 0.76; Specificity: 0.96)
|
| SMART Domains |
Protein: ENSMUSP00000112398
Gene: ENSMUSG00000054102
AA Change: I45F
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
8.8e-34 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
Blast:LRR
|
666 |
692 |
1e-5 |
BLAST |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.39e0 |
SMART |
|
LRR
|
807 |
834 |
6.24e1 |
SMART |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000122040
AA Change: I45F
PolyPhen 2
Score 0.997 (Sensitivity: 0.41; Specificity: 0.98)
|
| SMART Domains |
Protein: ENSMUSP00000113318
Gene: ENSMUSG00000054102
AA Change: I45F
| Domain | Start | End | E-Value | Type |
|---|
|
PYRIN
|
5 |
87 |
1.07e-25 |
SMART |
|
Pfam:NACHT
|
143 |
311 |
1e-32 |
PFAM |
|
LRR
|
637 |
664 |
1.42e0 |
SMART |
|
LRR
|
693 |
720 |
2.32e-1 |
SMART |
|
LRR
|
722 |
749 |
3e0 |
SMART |
|
LRR
|
750 |
777 |
1.12e-3 |
SMART |
|
LRR
|
779 |
806 |
2.17e0 |
SMART |
|
LRR
|
807 |
834 |
2.27e-4 |
SMART |
|
LRR
|
836 |
863 |
2.02e2 |
SMART |
|
LRR
|
864 |
891 |
6.24e1 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143149
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000153452
|
| SMART Domains |
Protein: ENSMUSP00000120498
Gene: ENSMUSG00000054102
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:NACHT
|
54 |
222 |
6.9e-33 |
PFAM |
|
LRR
|
542 |
569 |
1.42e0 |
SMART |
|
LRR
|
603 |
630 |
1.42e0 |
SMART |
|
Blast:LRR
|
632 |
657 |
1e-5 |
BLAST |
|
LRR
|
659 |
686 |
2.32e-1 |
SMART |
|
LRR
|
688 |
715 |
3e0 |
SMART |
|
LRR
|
716 |
743 |
1.12e-3 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.2%
- 20x: 92.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 99 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110059G10Rik |
T |
A |
9: 122,778,008 (GRCm39) |
I79L |
probably benign |
Het |
| Ablim2 |
C |
T |
5: 35,959,766 (GRCm39) |
R73C |
possibly damaging |
Het |
| Acaa1a |
G |
A |
9: 119,177,772 (GRCm39) |
S218N |
probably benign |
Het |
| Acsm5 |
A |
T |
7: 119,137,314 (GRCm39) |
I377F |
probably damaging |
Het |
| Ahnak2 |
T |
C |
12: 112,741,706 (GRCm39) |
T789A |
probably benign |
Het |
| Ak9 |
A |
T |
10: 41,296,678 (GRCm39) |
T1475S |
unknown |
Het |
| AU040320 |
A |
T |
4: 126,747,081 (GRCm39) |
N1028Y |
probably damaging |
Het |
| Bahcc1 |
T |
A |
11: 120,178,580 (GRCm39) |
S2380T |
probably benign |
Het |
| Cadps |
A |
G |
14: 12,536,386 (GRCm38) |
Y525H |
probably damaging |
Het |
| Casp8ap2 |
A |
G |
4: 32,639,905 (GRCm39) |
T320A |
possibly damaging |
Het |
| Ccdc138 |
A |
G |
10: 58,380,817 (GRCm39) |
N483D |
possibly damaging |
Het |
| Ccdc39 |
G |
A |
3: 33,893,242 (GRCm39) |
|
probably null |
Het |
| Cd300c2 |
T |
C |
11: 114,887,772 (GRCm39) |
N210S |
probably damaging |
Het |
| Cd84 |
A |
G |
1: 171,700,432 (GRCm39) |
D183G |
probably damaging |
Het |
| Cep95 |
C |
T |
11: 106,702,172 (GRCm39) |
P390S |
probably damaging |
Het |
| Chd9 |
A |
T |
8: 91,741,877 (GRCm39) |
H1622L |
possibly damaging |
Het |
| Cilp |
C |
A |
9: 65,185,302 (GRCm39) |
Q466K |
probably benign |
Het |
| Cinp |
T |
A |
12: 110,850,487 (GRCm39) |
T5S |
probably damaging |
Het |
| Clec4a2 |
T |
C |
6: 123,119,462 (GRCm39) |
L238S |
probably damaging |
Het |
| Cntrob |
T |
C |
11: 69,211,732 (GRCm39) |
Y164C |
probably damaging |
Het |
| Col6a3 |
A |
G |
1: 90,735,246 (GRCm39) |
L1408P |
probably damaging |
Het |
| Cul3 |
G |
A |
1: 80,258,632 (GRCm39) |
S468L |
possibly damaging |
Het |
| Dnah11 |
T |
A |
12: 118,090,618 (GRCm39) |
D1081V |
probably benign |
Het |
| Dnah2 |
C |
A |
11: 69,411,973 (GRCm39) |
V263L |
probably benign |
Het |
| Efna3 |
C |
G |
3: 89,222,805 (GRCm39) |
R185P |
probably damaging |
Het |
| F5 |
A |
T |
1: 164,039,389 (GRCm39) |
I2000F |
probably damaging |
Het |
| Fancm |
G |
A |
12: 65,141,645 (GRCm39) |
G422E |
probably benign |
Het |
| Gcnt2 |
A |
T |
13: 41,014,210 (GRCm39) |
D127V |
probably damaging |
Het |
| Gm21798 |
G |
T |
15: 64,689,618 (GRCm39) |
|
probably benign |
Het |
| Gramd1a |
A |
C |
7: 30,838,292 (GRCm39) |
S320R |
probably benign |
Het |
| Grn |
T |
C |
11: 102,327,344 (GRCm39) |
|
probably benign |
Het |
| Helq |
A |
T |
5: 100,910,507 (GRCm39) |
|
probably null |
Het |
| Herc2 |
A |
G |
7: 55,827,660 (GRCm39) |
I2914V |
probably benign |
Het |
| Hnrnph1 |
T |
C |
11: 50,269,237 (GRCm39) |
V27A |
probably damaging |
Het |
| Hs1bp3 |
G |
T |
12: 8,374,007 (GRCm39) |
G182C |
probably damaging |
Het |
| Idnk |
C |
T |
13: 58,311,267 (GRCm39) |
P78L |
probably benign |
Het |
| Il10ra |
T |
C |
9: 45,166,919 (GRCm39) |
D544G |
probably benign |
Het |
| Inpp5e |
T |
C |
2: 26,290,918 (GRCm39) |
D383G |
probably damaging |
Het |
| Jak1 |
A |
T |
4: 101,036,911 (GRCm39) |
V243D |
probably damaging |
Het |
| Kcnma1 |
A |
T |
14: 23,359,220 (GRCm39) |
S1036T |
probably damaging |
Het |
| Kif26a |
G |
A |
12: 112,123,776 (GRCm39) |
C127Y |
probably damaging |
Het |
| Kif2c |
T |
C |
4: 117,023,608 (GRCm39) |
E368G |
probably damaging |
Het |
| Lasp1 |
T |
A |
11: 97,724,530 (GRCm39) |
|
probably null |
Het |
| Lcor |
T |
A |
19: 41,572,601 (GRCm39) |
V452D |
probably benign |
Het |
| Lrrtm1 |
C |
G |
6: 77,221,661 (GRCm39) |
H373D |
probably benign |
Het |
| Matr3 |
T |
A |
18: 35,705,754 (GRCm39) |
D226E |
probably damaging |
Het |
| Mmp17 |
G |
A |
5: 129,682,730 (GRCm39) |
W456* |
probably null |
Het |
| Mpp4 |
T |
C |
1: 59,164,748 (GRCm39) |
E463G |
probably damaging |
Het |
| Myh6 |
A |
C |
14: 55,194,419 (GRCm39) |
F737V |
probably damaging |
Het |
| Nars2 |
T |
A |
7: 96,672,948 (GRCm39) |
D271E |
probably benign |
Het |
| Nav2 |
A |
G |
7: 49,254,258 (GRCm39) |
E2352G |
probably damaging |
Het |
| Nckap1 |
A |
G |
2: 80,353,718 (GRCm39) |
|
probably null |
Het |
| Nckap5 |
A |
T |
1: 125,955,324 (GRCm39) |
S477R |
probably damaging |
Het |
| Nek11 |
T |
G |
9: 105,175,488 (GRCm39) |
I319L |
probably benign |
Het |
| Neto2 |
A |
G |
8: 86,396,393 (GRCm39) |
I84T |
probably damaging |
Het |
| Numa1 |
G |
A |
7: 101,662,012 (GRCm39) |
R548H |
probably damaging |
Het |
| Or10a5 |
A |
C |
7: 106,635,364 (GRCm39) |
M1L |
probably benign |
Het |
| Or14c39 |
A |
C |
7: 86,344,395 (GRCm39) |
I244L |
probably benign |
Het |
| Or2ag1b |
A |
T |
7: 106,288,740 (GRCm39) |
L66H |
probably damaging |
Het |
| Or4c10 |
A |
T |
2: 89,760,923 (GRCm39) |
M257L |
probably benign |
Het |
| Or4c100 |
T |
A |
2: 88,356,254 (GRCm39) |
I109N |
probably damaging |
Het |
| Or4k36 |
T |
A |
2: 111,146,574 (GRCm39) |
F250Y |
probably benign |
Het |
| Or7g25 |
A |
G |
9: 19,160,149 (GRCm39) |
V182A |
probably benign |
Het |
| Or9m1 |
A |
T |
2: 87,733,533 (GRCm39) |
N162K |
probably damaging |
Het |
| Pcdhb16 |
T |
A |
18: 37,612,894 (GRCm39) |
|
probably null |
Het |
| Pdcd10 |
T |
C |
3: 75,448,553 (GRCm39) |
T4A |
probably damaging |
Het |
| Pgc |
A |
T |
17: 48,039,819 (GRCm39) |
Y71F |
probably damaging |
Het |
| Phlpp1 |
G |
A |
1: 106,317,481 (GRCm39) |
G1234E |
probably damaging |
Het |
| Prr27 |
T |
C |
5: 87,990,888 (GRCm39) |
F167L |
probably benign |
Het |
| Prrc2b |
T |
A |
2: 32,116,330 (GRCm39) |
S1421T |
possibly damaging |
Het |
| Pxmp2 |
A |
G |
5: 110,431,518 (GRCm39) |
V75A |
probably benign |
Het |
| Pygl |
A |
T |
12: 70,243,807 (GRCm39) |
M545K |
probably null |
Het |
| Ranbp9 |
A |
G |
13: 43,574,733 (GRCm39) |
Y412H |
possibly damaging |
Het |
| Rcc1 |
A |
G |
4: 132,065,064 (GRCm39) |
V140A |
probably damaging |
Het |
| Reln |
A |
G |
5: 22,184,718 (GRCm39) |
V1599A |
probably benign |
Het |
| Rhebl1 |
A |
T |
15: 98,776,903 (GRCm39) |
D122E |
probably damaging |
Het |
| Rock2 |
C |
T |
12: 17,009,492 (GRCm39) |
L676F |
probably benign |
Het |
| Scn9a |
A |
T |
2: 66,357,087 (GRCm39) |
D1062E |
probably benign |
Het |
| Sec63 |
T |
C |
10: 42,681,186 (GRCm39) |
I390T |
probably damaging |
Het |
| Slc10a6 |
T |
C |
5: 103,754,493 (GRCm39) |
E346G |
probably benign |
Het |
| Slc12a3 |
G |
A |
8: 95,075,216 (GRCm39) |
V737M |
possibly damaging |
Het |
| Slc12a8 |
T |
C |
16: 33,426,629 (GRCm39) |
|
probably null |
Het |
| Slc25a38 |
T |
A |
9: 119,949,354 (GRCm39) |
I102N |
probably damaging |
Het |
| Spg7 |
T |
A |
8: 123,807,394 (GRCm39) |
V390E |
probably damaging |
Het |
| Tbc1d20 |
T |
C |
2: 152,144,228 (GRCm39) |
V75A |
probably benign |
Het |
| Tesk1 |
T |
A |
4: 43,445,555 (GRCm39) |
C243* |
probably null |
Het |
| Ttk |
T |
A |
9: 83,725,739 (GRCm39) |
N220K |
possibly damaging |
Het |
| Ttll5 |
A |
G |
12: 85,965,948 (GRCm39) |
E651G |
probably benign |
Het |
| Tubd1 |
T |
C |
11: 86,457,879 (GRCm39) |
Y426H |
probably damaging |
Het |
| Uba6 |
T |
C |
5: 86,288,293 (GRCm39) |
|
silent |
Het |
| Ube2ql1 |
G |
A |
13: 69,852,289 (GRCm39) |
R263W |
probably damaging |
Het |
| Vmn2r117 |
C |
T |
17: 23,678,812 (GRCm39) |
G804D |
probably damaging |
Het |
| Vmn2r25 |
C |
T |
6: 123,805,406 (GRCm39) |
E484K |
probably benign |
Het |
| Vmn2r4 |
T |
A |
3: 64,296,476 (GRCm39) |
I770F |
possibly damaging |
Het |
| Vmn2r82 |
G |
A |
10: 79,214,589 (GRCm39) |
V191M |
probably benign |
Het |
| Zbtb45 |
C |
T |
7: 12,742,037 (GRCm39) |
V74M |
probably damaging |
Het |
| Zfp366 |
T |
C |
13: 99,370,609 (GRCm39) |
V443A |
possibly damaging |
Het |
| Zfyve1 |
A |
T |
12: 83,598,345 (GRCm39) |
C628S |
probably damaging |
Het |
| Zfyve26 |
A |
T |
12: 79,296,469 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Nlrp9a |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00659:Nlrp9a
|
APN |
7 |
26,257,050 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL00895:Nlrp9a
|
APN |
7 |
26,258,103 (GRCm39) |
missense |
probably benign |
|
|
IGL01081:Nlrp9a
|
APN |
7 |
26,257,519 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
IGL01148:Nlrp9a
|
APN |
7 |
26,257,006 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01368:Nlrp9a
|
APN |
7 |
26,257,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01914:Nlrp9a
|
APN |
7 |
26,256,689 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01952:Nlrp9a
|
APN |
7 |
26,257,444 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02245:Nlrp9a
|
APN |
7 |
26,257,318 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02449:Nlrp9a
|
APN |
7 |
26,264,396 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02702:Nlrp9a
|
APN |
7 |
26,264,381 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
IGL02944:Nlrp9a
|
APN |
7 |
26,258,076 (GRCm39) |
missense |
probably benign |
0.28 |
|
IGL03183:Nlrp9a
|
APN |
7 |
26,256,882 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0005:Nlrp9a
|
UTSW |
7 |
26,273,213 (GRCm39) |
splice site |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0007:Nlrp9a
|
UTSW |
7 |
26,250,515 (GRCm39) |
intron |
probably benign |
|
|
R0013:Nlrp9a
|
UTSW |
7 |
26,270,650 (GRCm39) |
splice site |
probably null |
|
|
R0086:Nlrp9a
|
UTSW |
7 |
26,257,972 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0659:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1126:Nlrp9a
|
UTSW |
7 |
26,260,166 (GRCm39) |
missense |
probably benign |
0.12 |
|
R1500:Nlrp9a
|
UTSW |
7 |
26,267,316 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1585:Nlrp9a
|
UTSW |
7 |
26,258,093 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1594:Nlrp9a
|
UTSW |
7 |
26,269,932 (GRCm39) |
nonsense |
probably null |
|
|
R1968:Nlrp9a
|
UTSW |
7 |
26,264,366 (GRCm39) |
missense |
probably benign |
0.23 |
|
R1989:Nlrp9a
|
UTSW |
7 |
26,273,338 (GRCm39) |
missense |
probably benign |
0.24 |
|
R2057:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2058:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2059:Nlrp9a
|
UTSW |
7 |
26,256,787 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R2188:Nlrp9a
|
UTSW |
7 |
26,264,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2318:Nlrp9a
|
UTSW |
7 |
26,273,277 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3110:Nlrp9a
|
UTSW |
7 |
26,257,297 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3112:Nlrp9a
|
UTSW |
7 |
26,257,297 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3237:Nlrp9a
|
UTSW |
7 |
26,270,810 (GRCm39) |
nonsense |
probably null |
|
|
R3545:Nlrp9a
|
UTSW |
7 |
26,256,757 (GRCm39) |
missense |
probably benign |
0.03 |
|
R3805:Nlrp9a
|
UTSW |
7 |
26,264,277 (GRCm39) |
nonsense |
probably null |
|
|
R4005:Nlrp9a
|
UTSW |
7 |
26,257,975 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4057:Nlrp9a
|
UTSW |
7 |
26,270,071 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4529:Nlrp9a
|
UTSW |
7 |
26,270,832 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4756:Nlrp9a
|
UTSW |
7 |
26,256,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4972:Nlrp9a
|
UTSW |
7 |
26,269,964 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4992:Nlrp9a
|
UTSW |
7 |
26,256,811 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5042:Nlrp9a
|
UTSW |
7 |
26,270,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5224:Nlrp9a
|
UTSW |
7 |
26,256,717 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5449:Nlrp9a
|
UTSW |
7 |
26,257,254 (GRCm39) |
missense |
probably benign |
0.04 |
|
R5644:Nlrp9a
|
UTSW |
7 |
26,257,993 (GRCm39) |
missense |
possibly damaging |
0.51 |
|
R5734:Nlrp9a
|
UTSW |
7 |
26,270,065 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5905:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5978:Nlrp9a
|
UTSW |
7 |
26,256,703 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6028:Nlrp9a
|
UTSW |
7 |
26,257,762 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6066:Nlrp9a
|
UTSW |
7 |
26,257,510 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6082:Nlrp9a
|
UTSW |
7 |
26,267,402 (GRCm39) |
missense |
probably benign |
0.41 |
|
R6171:Nlrp9a
|
UTSW |
7 |
26,258,188 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R6352:Nlrp9a
|
UTSW |
7 |
26,257,051 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6490:Nlrp9a
|
UTSW |
7 |
26,250,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6540:Nlrp9a
|
UTSW |
7 |
26,256,817 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7039:Nlrp9a
|
UTSW |
7 |
26,267,367 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7151:Nlrp9a
|
UTSW |
7 |
26,256,672 (GRCm39) |
nonsense |
probably null |
|
|
R7173:Nlrp9a
|
UTSW |
7 |
26,257,603 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7214:Nlrp9a
|
UTSW |
7 |
26,250,463 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7226:Nlrp9a
|
UTSW |
7 |
26,258,149 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7250:Nlrp9a
|
UTSW |
7 |
26,258,143 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7293:Nlrp9a
|
UTSW |
7 |
26,270,694 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7492:Nlrp9a
|
UTSW |
7 |
26,257,081 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7586:Nlrp9a
|
UTSW |
7 |
26,256,721 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7844:Nlrp9a
|
UTSW |
7 |
26,262,006 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8073:Nlrp9a
|
UTSW |
7 |
26,260,260 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8136:Nlrp9a
|
UTSW |
7 |
26,256,678 (GRCm39) |
missense |
probably benign |
0.34 |
|
R8400:Nlrp9a
|
UTSW |
7 |
26,264,431 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8415:Nlrp9a
|
UTSW |
7 |
26,256,925 (GRCm39) |
missense |
probably benign |
|
|
R8774:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8774-TAIL:Nlrp9a
|
UTSW |
7 |
26,257,984 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R8882:Nlrp9a
|
UTSW |
7 |
26,257,703 (GRCm39) |
nonsense |
probably null |
|
|
R9023:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9031:Nlrp9a
|
UTSW |
7 |
26,257,698 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9063:Nlrp9a
|
UTSW |
7 |
26,273,291 (GRCm39) |
missense |
possibly damaging |
0.62 |
|
R9090:Nlrp9a
|
UTSW |
7 |
26,261,944 (GRCm39) |
missense |
probably benign |
|
|
R9196:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9206:Nlrp9a
|
UTSW |
7 |
26,257,656 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R9265:Nlrp9a
|
UTSW |
7 |
26,258,038 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R9271:Nlrp9a
|
UTSW |
7 |
26,261,944 (GRCm39) |
missense |
probably benign |
|
|
R9384:Nlrp9a
|
UTSW |
7 |
26,258,158 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9402:Nlrp9a
|
UTSW |
7 |
26,270,030 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9424:Nlrp9a
|
UTSW |
7 |
26,260,178 (GRCm39) |
missense |
probably benign |
0.13 |
|
R9620:Nlrp9a
|
UTSW |
7 |
26,250,469 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9660:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9696:Nlrp9a
|
UTSW |
7 |
26,275,033 (GRCm39) |
missense |
unknown |
|
|
R9728:Nlrp9a
|
UTSW |
7 |
26,256,915 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9744:Nlrp9a
|
UTSW |
7 |
26,267,266 (GRCm39) |
missense |
probably benign |
0.07 |
|
R9794:Nlrp9a
|
UTSW |
7 |
26,264,302 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1176:Nlrp9a
|
UTSW |
7 |
26,257,654 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Nlrp9a
|
UTSW |
7 |
26,256,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACTGGACTCTCATGTCAAACC -3'
(R):5'- ACTTGGGTAACTTTCCTCATATGTC -3'
Sequencing Primer
(F):5'- GGACTCTCATGTCAAACCTCTTTG -3'
(R):5'- GTAACTTTCCTCATATGTCCCCTTTC -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation