Mutagenetix > Incidental Mutation

Incidental Mutation 'R4910:Arid1b'

379453

Institutional Source

Beutler Lab

Gene Symbol

Arid1b

Ensembl Gene

ENSMUSG00000069729

Gene Name

AT-rich interaction domain 1B

Synonyms

9330189K18Rik, B230217J03Rik

MMRRC Submission

042512-MU

Accession Numbers

Essential gene?

Probably essential (E-score: 0.783) question?

Stock #

R4910 (G1)

Quality Score

154

Status

Validated

Chromosome

Chromosomal Location

5044607-5397931 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to A at 5392478 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Threonine at position 2003 (S2003T)

Ref Sequence

ENSEMBL: ENSMUSP00000156119 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000092723] [ENSMUST00000115797] [ENSMUST00000115799] [ENSMUST00000232180]

AlphaFold

E9Q4N7

Predicted Effect

probably damaging
Transcript: ENSMUST00000092723
AA Change: S1950T

PolyPhen 2 Score 0.975 (Sensitivity: 0.76; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000090398
Gene: ENSMUSG00000069729
AA Change: S1950T

Domain	Start	End	E-Value	Type
low complexity region	2	51	N/A	INTRINSIC
low complexity region	69	132	N/A	INTRINSIC
low complexity region	139	150	N/A	INTRINSIC
low complexity region	201	224	N/A	INTRINSIC
low complexity region	232	247	N/A	INTRINSIC
low complexity region	257	276	N/A	INTRINSIC
low complexity region	301	371	N/A	INTRINSIC
low complexity region	379	407	N/A	INTRINSIC
low complexity region	438	476	N/A	INTRINSIC
low complexity region	485	499	N/A	INTRINSIC
low complexity region	538	558	N/A	INTRINSIC
low complexity region	574	591	N/A	INTRINSIC
low complexity region	596	611	N/A	INTRINSIC
low complexity region	615	640	N/A	INTRINSIC
low complexity region	691	707	N/A	INTRINSIC
low complexity region	719	740	N/A	INTRINSIC
low complexity region	743	773	N/A	INTRINSIC
low complexity region	805	816	N/A	INTRINSIC
low complexity region	912	930	N/A	INTRINSIC
low complexity region	936	952	N/A	INTRINSIC
low complexity region	974	985	N/A	INTRINSIC
low complexity region	1036	1045	N/A	INTRINSIC
ARID	1057	1147	9.9e-33	SMART
BRIGHT	1061	1152	7.62e-41	SMART
low complexity region	1166	1177	N/A	INTRINSIC
low complexity region	1257	1268	N/A	INTRINSIC
low complexity region	1336	1364	N/A	INTRINSIC
low complexity region	1426	1456	N/A	INTRINSIC
low complexity region	1473	1486	N/A	INTRINSIC
low complexity region	1579	1595	N/A	INTRINSIC
coiled coil region	1724	1745	N/A	INTRINSIC
low complexity region	1835	1843	N/A	INTRINSIC
Pfam:DUF3518	1933	2189	1.5e-152	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000115797
AA Change: S1951T

PolyPhen 2 Score 0.975 (Sensitivity: 0.76; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000111463
Gene: ENSMUSG00000069729
AA Change: S1951T

Domain	Start	End	E-Value	Type
low complexity region	17	80	N/A	INTRINSIC
low complexity region	87	98	N/A	INTRINSIC
low complexity region	149	172	N/A	INTRINSIC
low complexity region	180	195	N/A	INTRINSIC
low complexity region	205	224	N/A	INTRINSIC
low complexity region	249	319	N/A	INTRINSIC
low complexity region	327	355	N/A	INTRINSIC
low complexity region	386	424	N/A	INTRINSIC
low complexity region	433	447	N/A	INTRINSIC
low complexity region	486	506	N/A	INTRINSIC
low complexity region	522	539	N/A	INTRINSIC
low complexity region	544	559	N/A	INTRINSIC
low complexity region	563	588	N/A	INTRINSIC
low complexity region	639	655	N/A	INTRINSIC
low complexity region	667	688	N/A	INTRINSIC
low complexity region	691	721	N/A	INTRINSIC
low complexity region	753	764	N/A	INTRINSIC
low complexity region	860	878	N/A	INTRINSIC
low complexity region	884	900	N/A	INTRINSIC
low complexity region	922	933	N/A	INTRINSIC
Blast:ARID	981	1028	1e-8	BLAST
low complexity region	1029	1054	N/A	INTRINSIC
ARID	1058	1148	9.9e-33	SMART
BRIGHT	1062	1153	7.62e-41	SMART
low complexity region	1167	1178	N/A	INTRINSIC
low complexity region	1258	1269	N/A	INTRINSIC
low complexity region	1337	1365	N/A	INTRINSIC
low complexity region	1427	1457	N/A	INTRINSIC
low complexity region	1474	1487	N/A	INTRINSIC
low complexity region	1580	1596	N/A	INTRINSIC
coiled coil region	1725	1746	N/A	INTRINSIC
low complexity region	1836	1844	N/A	INTRINSIC
Pfam:DUF3518	1935	2190	6.3e-121	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000115799
AA Change: S1469T

PolyPhen 2 Score 0.975 (Sensitivity: 0.76; Specificity: 0.96)

SMART Domains

Protein: ENSMUSP00000111465
Gene: ENSMUSG00000069729
AA Change: S1469T

Domain	Start	End	E-Value	Type
low complexity region	34	54	N/A	INTRINSIC
low complexity region	70	87	N/A	INTRINSIC
low complexity region	92	107	N/A	INTRINSIC
low complexity region	111	136	N/A	INTRINSIC
low complexity region	187	203	N/A	INTRINSIC
low complexity region	215	236	N/A	INTRINSIC
low complexity region	271	282	N/A	INTRINSIC
low complexity region	378	396	N/A	INTRINSIC
low complexity region	402	418	N/A	INTRINSIC
low complexity region	440	451	N/A	INTRINSIC
Blast:ARID	499	546	1e-8	BLAST
low complexity region	547	572	N/A	INTRINSIC
ARID	576	666	9.9e-33	SMART
BRIGHT	580	671	7.62e-41	SMART
low complexity region	685	696	N/A	INTRINSIC
low complexity region	776	787	N/A	INTRINSIC
low complexity region	855	883	N/A	INTRINSIC
low complexity region	945	975	N/A	INTRINSIC
low complexity region	992	1005	N/A	INTRINSIC
low complexity region	1098	1114	N/A	INTRINSIC
coiled coil region	1243	1264	N/A	INTRINSIC
low complexity region	1354	1362	N/A	INTRINSIC
Pfam:DUF3518	1452	1708	1.1e-152	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000232180
AA Change: S2003T

PolyPhen 2 Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)

Meta Mutation Damage Score

0.3325

Coding Region Coverage

1x: 98.9%
3x: 97.9%
10x: 94.6%
20x: 86.1%

Validation Efficiency

95% (144/151)

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This locus encodes an AT-rich DNA interacting domain-containing protein. The encoded protein is a component of the SWI/SNF chromatin remodeling complex and may play a role in cell-cycle activation. The protein encoded by this locus is similar to AT-rich interactive domain-containing protein 1A. These two proteins function as alternative, mutually exclusive ARID-subunits of the SWI/SNF complex. The associated complexes play opposing roles. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Oct 2016]

Allele List at MGI

All alleles(61) : Targeted(2) Gene trapped(59)

Other mutations in this stock

Total: 123 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aadacl2fm3	T	A	3: 59,776,435 (GRCm39)		probably null	Het
Adam3	T	A	8: 25,184,321 (GRCm39)	I560L	probably benign	Het
Agxt	T	C	1: 93,063,436 (GRCm39)	F113L	probably benign	Het
Aknad1	T	A	3: 108,688,568 (GRCm39)		probably null	Het
Alpk2	T	A	18: 65,399,357 (GRCm39)	K2074*	probably null	Het
Apob	A	G	12: 8,057,848 (GRCm39)	Y2077C	probably damaging	Het
Arhgap17	A	T	7: 122,907,600 (GRCm39)	L254Q	probably damaging	Het
Arhgap26	T	A	18: 39,126,690 (GRCm39)		probably benign	Het
Arhgef5	A	G	6: 43,249,762 (GRCm39)	D171G	probably benign	Het
Armc5	T	G	7: 127,839,900 (GRCm39)	L406R	possibly damaging	Het
Arsb	T	C	13: 93,908,485 (GRCm39)	V67A	probably benign	Het
Aspm	A	G	1: 139,419,281 (GRCm39)	Y2982C	probably damaging	Het
Bltp1	C	A	3: 37,052,348 (GRCm39)	T3016K	probably damaging	Het
Btbd7	A	G	12: 102,774,307 (GRCm39)	L487P	probably damaging	Het
Card11	C	G	5: 140,860,169 (GRCm39)	D1063H	probably damaging	Het
Ccdc186	G	A	19: 56,787,123 (GRCm39)	T615M	probably damaging	Het
Cd101	T	A	3: 100,901,205 (GRCm39)	T960S	probably benign	Het
Cdca7l	C	A	12: 117,837,520 (GRCm39)	S191*	probably null	Het
Cemip	A	T	7: 83,646,619 (GRCm39)	I143N	probably damaging	Het
Cep170	C	T	1: 176,609,829 (GRCm39)	E161K	possibly damaging	Het
Cfhr4	T	G	1: 139,702,301 (GRCm39)	D61A	probably damaging	Het
Chrm2	A	T	6: 36,501,168 (GRCm39)	T342S	probably benign	Het
Cib2	A	G	9: 54,457,163 (GRCm39)	F34L	probably benign	Het
Cnot1	A	T	8: 96,459,859 (GRCm39)	I1836N	probably benign	Het
Col4a3	C	A	1: 82,650,400 (GRCm39)	P552Q	unknown	Het
Cp	T	A	3: 20,043,388 (GRCm39)		probably benign	Het
Cul3	C	T	1: 80,267,806 (GRCm39)	V112I	probably benign	Het
Dcdc5	A	G	2: 106,195,895 (GRCm39)		noncoding transcript	Het
Disp1	A	T	1: 182,917,027 (GRCm39)	V133E	probably damaging	Het
Dlg4	A	G	11: 69,921,751 (GRCm39)	D30G	probably damaging	Het
Dop1a	C	T	9: 86,374,114 (GRCm39)	T191I	probably damaging	Het
Enam	T	G	5: 88,650,173 (GRCm39)	S561A	probably benign	Het
Fbxw8	G	T	5: 118,263,092 (GRCm39)		probably null	Het
Filip1	A	G	9: 79,725,214 (GRCm39)	V1135A	probably benign	Het
Galnt6	T	C	15: 100,614,059 (GRCm39)	T81A	probably benign	Het
Ghdc	T	C	11: 100,657,814 (GRCm39)	K472E	probably benign	Het
Gm10568	T	G	1: 3,751,164 (GRCm39)		noncoding transcript	Het
Gm4953	T	A	1: 158,995,929 (GRCm39)		noncoding transcript	Het
Gm6871	T	A	7: 41,223,016 (GRCm39)	H24L	probably benign	Het
Gpr155	G	A	2: 73,197,882 (GRCm39)	Q413*	probably null	Het
Grhl2	A	G	15: 37,291,920 (GRCm39)		probably null	Het
Ighv1-31	G	C	12: 114,793,128 (GRCm39)	S36*	probably null	Het
Ighv8-5	A	G	12: 115,031,462 (GRCm39)	S26P	probably damaging	Het
Igkv17-134	A	C	6: 67,697,910 (GRCm39)		probably benign	Het
Igkv5-48	A	C	6: 69,703,833 (GRCm39)	L24R	probably damaging	Het
Isg20l2	T	A	3: 87,846,570 (GRCm39)	V340E	probably damaging	Het
Lrrtm1	A	G	6: 77,221,884 (GRCm39)	Y447C	probably damaging	Het
Ltbp1	T	C	17: 75,634,287 (GRCm39)	S855P	probably damaging	Het
Mgat4e	A	T	1: 134,469,602 (GRCm39)	N147K	probably damaging	Het
Mlc1	A	G	15: 88,842,415 (GRCm39)	L315P	possibly damaging	Het
Mrgpra2a	A	G	7: 47,076,292 (GRCm39)	V322A	probably benign	Het
Mroh7	T	C	4: 106,567,152 (GRCm39)		probably null	Het
Mybpc1	T	A	10: 88,391,586 (GRCm39)	K304*	probably null	Het
Nlrp14	A	C	7: 106,785,790 (GRCm39)	D622A	possibly damaging	Het
Nlrp1b	T	A	11: 71,108,103 (GRCm39)	H466L	probably benign	Het
Nlrp4d	T	A	7: 10,112,336 (GRCm39)		noncoding transcript	Het
Nrxn3	A	G	12: 89,227,130 (GRCm39)	E628G	possibly damaging	Het
Nup133	T	C	8: 124,653,870 (GRCm39)	R530G	possibly damaging	Het
Nup98	A	G	7: 101,845,007 (GRCm39)	S21P	unknown	Het
Or2h2b-ps1	T	C	17: 37,480,934 (GRCm39)	I202V	probably benign	Het
Or2l13b	T	C	16: 19,348,768 (GRCm39)	T301A	probably benign	Het
Or4f14b	A	T	2: 111,775,423 (GRCm39)	I126K	possibly damaging	Het
Or52e8	G	A	7: 104,624,686 (GRCm39)	P169S	possibly damaging	Het
Or5k1	T	A	16: 58,617,805 (GRCm39)	T135S	probably benign	Het
Or6c66	T	C	10: 129,461,676 (GRCm39)	T85A	probably damaging	Het
Or8c11	T	A	9: 38,290,038 (GRCm39)	V287E	probably null	Het
Otog	A	T	7: 45,913,486 (GRCm39)	Y773F	probably damaging	Het
Otog	A	T	7: 45,947,958 (GRCm39)	I2320F	probably damaging	Het
Otogl	T	C	10: 107,715,378 (GRCm39)	S433G	probably benign	Het
Pcdhb17	A	T	18: 37,618,212 (GRCm39)	M1L	possibly damaging	Het
Pde7b	T	A	10: 20,600,480 (GRCm39)		probably benign	Het
Pgm1	T	C	4: 99,820,724 (GRCm39)	V207A	probably damaging	Het
Pkd1	T	A	17: 24,791,661 (GRCm39)	V1116E	probably damaging	Het
Pkd1l1	T	A	11: 8,879,360 (GRCm39)	Y497F	possibly damaging	Het
Pomgnt2	T	C	9: 121,812,013 (GRCm39)	N256S	probably benign	Het
Pot1a	A	T	6: 25,746,020 (GRCm39)		probably benign	Het
Prdm9	T	C	17: 15,764,585 (GRCm39)	T732A	probably benign	Het
Prg4	T	A	1: 150,331,574 (GRCm39)		probably benign	Het
Ptpro	T	C	6: 137,345,336 (GRCm39)	V114A	probably damaging	Het
Pyurf	A	G	6: 57,668,933 (GRCm39)	S20P	unknown	Het
Rasgrf1	A	G	9: 89,858,805 (GRCm39)	T488A	probably benign	Het
Rassf8	A	T	6: 145,761,006 (GRCm39)	K111*	probably null	Het
Reps1	A	T	10: 17,983,436 (GRCm39)	E426D	probably damaging	Het
Robo2	T	C	16: 73,730,666 (GRCm39)	K982R	probably damaging	Het
Rps23	T	C	13: 91,071,871 (GRCm39)		probably null	Het
Scamp4	T	A	10: 80,445,505 (GRCm39)	V56E	probably damaging	Het
Serpina1c	C	T	12: 103,861,291 (GRCm39)	V408I	probably benign	Het
Sigirr	A	G	7: 140,673,701 (GRCm39)	W49R	probably damaging	Het
Slc17a6	A	T	7: 51,308,489 (GRCm39)	H271L	possibly damaging	Het
Slc7a5	G	T	8: 122,611,861 (GRCm39)	T389K	probably damaging	Het
Slf1	T	A	13: 77,191,999 (GRCm39)	H945L	probably benign	Het
Slit3	T	C	11: 35,523,549 (GRCm39)	S662P	probably damaging	Het
Snta1	C	A	2: 154,218,938 (GRCm39)	E466*	probably null	Het
Sowaha	A	G	11: 53,369,272 (GRCm39)	L488P	probably damaging	Het
Spata17	C	A	1: 186,926,208 (GRCm39)	V41F	probably damaging	Het
Spta1	T	A	1: 174,045,429 (GRCm39)		probably null	Het
Srrm2	T	A	17: 24,034,362 (GRCm39)		probably benign	Het
Stard13	T	C	5: 150,985,992 (GRCm39)	N388S	probably benign	Het
Stmn3	T	C	2: 180,950,630 (GRCm39)	K59E	probably damaging	Het
Sval1	A	G	6: 41,932,378 (GRCm39)	N76S	probably benign	Het
Svep1	T	C	4: 58,096,276 (GRCm39)	H1448R	possibly damaging	Het
Sycp2	A	T	2: 178,000,017 (GRCm39)	D986E	probably benign	Het
Sytl5	C	T	X: 9,781,841 (GRCm39)	P181L	possibly damaging	Het
Tbkbp1	G	A	11: 97,029,956 (GRCm39)	S400L	probably benign	Het
Tesc	G	T	5: 118,194,531 (GRCm39)		probably benign	Het
Tjp1	C	T	7: 64,993,475 (GRCm39)	G33R	probably damaging	Het
Tlr11	C	A	14: 50,600,346 (GRCm39)	F777L	probably benign	Het
Tmem156	A	G	5: 65,248,805 (GRCm39)		probably benign	Het
Top3a	A	G	11: 60,643,204 (GRCm39)		probably benign	Het
Tpcn1	A	G	5: 120,694,584 (GRCm39)	W162R	probably damaging	Het
Tpd52l2	A	T	2: 181,157,005 (GRCm39)		probably benign	Het
Trim80	G	A	11: 115,337,281 (GRCm39)	G381D	probably damaging	Het
Ugt1a10	C	T	1: 88,142,845 (GRCm39)	P113L	probably damaging	Het
Vmn2r117	TC	T	17: 23,698,487 (GRCm39)		probably null	Het
Vmn2r56	T	A	7: 12,449,462 (GRCm39)	I259F	possibly damaging	Het
Vmn2r59	T	C	7: 41,693,077 (GRCm39)	T508A	probably benign	Het
Wdr73	A	G	7: 80,541,456 (GRCm39)	V362A	probably damaging	Het
Zdhhc21	G	T	4: 82,738,568 (GRCm39)	T207K	possibly damaging	Het
Zfp120	T	A	2: 149,959,872 (GRCm39)	Q150L	probably damaging	Het
Zfp212	C	A	6: 47,908,433 (GRCm39)	Q471K	possibly damaging	Het
Zfp804b	C	T	5: 6,820,540 (GRCm39)	G841D	possibly damaging	Het
Znfx1	A	T	2: 166,878,724 (GRCm39)	M1884K	probably damaging	Het
Znfx1	G	T	2: 166,879,402 (GRCm39)	A1658D	probably benign	Het

Other mutations in Arid1b

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00325:Arid1b	APN	17	5,387,385 (GRCm39)	missense	possibly damaging	0.77
IGL00340:Arid1b	APN	17	5,371,559 (GRCm39)	missense	probably damaging	1.00
IGL00886:Arid1b	APN	17	5,177,254 (GRCm39)	missense	probably damaging	0.99
IGL01161:Arid1b	APN	17	5,392,674 (GRCm39)	missense	probably damaging	1.00
IGL01391:Arid1b	APN	17	5,369,133 (GRCm39)	splice site	probably benign
IGL01456:Arid1b	APN	17	5,341,510 (GRCm39)	missense	probably damaging	1.00
IGL02152:Arid1b	APN	17	5,364,243 (GRCm39)	missense	probably damaging	1.00
IGL02288:Arid1b	APN	17	5,314,315 (GRCm39)	missense	possibly damaging	0.88
IGL02713:Arid1b	APN	17	5,393,286 (GRCm39)	missense	probably damaging	1.00
IGL02858:Arid1b	APN	17	5,392,166 (GRCm39)	missense	possibly damaging	0.92
IGL02885:Arid1b	APN	17	5,392,428 (GRCm39)	missense	probably damaging	1.00
IGL02989:Arid1b	APN	17	5,385,322 (GRCm39)	missense	probably damaging	1.00
FR4449:Arid1b	UTSW	17	5,045,864 (GRCm39)	small insertion	probably benign
PIT4142001:Arid1b	UTSW	17	5,389,518 (GRCm39)	missense	probably damaging	1.00
R0048:Arid1b	UTSW	17	5,364,309 (GRCm39)	critical splice donor site	probably null
R0124:Arid1b	UTSW	17	5,389,605 (GRCm39)	missense	probably damaging	1.00
R0153:Arid1b	UTSW	17	5,393,207 (GRCm39)	missense	probably damaging	1.00
R0465:Arid1b	UTSW	17	5,046,535 (GRCm39)	missense	possibly damaging	0.68
R0825:Arid1b	UTSW	17	5,392,453 (GRCm39)	missense	probably damaging	1.00
R1172:Arid1b	UTSW	17	5,389,575 (GRCm39)	missense	probably damaging	1.00
R1468:Arid1b	UTSW	17	5,293,197 (GRCm39)	missense	probably damaging	0.99
R1468:Arid1b	UTSW	17	5,293,197 (GRCm39)	missense	probably damaging	0.99
R1616:Arid1b	UTSW	17	5,389,569 (GRCm39)	missense	probably damaging	1.00
R1754:Arid1b	UTSW	17	5,329,476 (GRCm39)	critical splice acceptor site	probably null
R1760:Arid1b	UTSW	17	5,392,088 (GRCm39)	missense	probably damaging	0.97
R1812:Arid1b	UTSW	17	5,387,304 (GRCm39)	missense	probably benign	0.10
R1911:Arid1b	UTSW	17	5,393,241 (GRCm39)	missense	probably damaging	1.00
R3874:Arid1b	UTSW	17	5,386,790 (GRCm39)	splice site	probably null
R3913:Arid1b	UTSW	17	5,392,532 (GRCm39)	missense	possibly damaging	0.94
R3916:Arid1b	UTSW	17	5,392,928 (GRCm39)	missense	probably benign	0.25
R3922:Arid1b	UTSW	17	5,393,316 (GRCm39)	missense	probably damaging	0.97
R4119:Arid1b	UTSW	17	5,046,069 (GRCm39)	unclassified	probably benign
R4290:Arid1b	UTSW	17	5,090,938 (GRCm39)	missense	probably damaging	1.00
R4291:Arid1b	UTSW	17	5,090,938 (GRCm39)	missense	probably damaging	1.00
R4352:Arid1b	UTSW	17	5,147,859 (GRCm39)	missense	possibly damaging	0.93
R4386:Arid1b	UTSW	17	5,045,247 (GRCm39)	unclassified	probably benign
R4458:Arid1b	UTSW	17	5,293,191 (GRCm39)	missense	probably damaging	0.99
R4524:Arid1b	UTSW	17	5,147,895 (GRCm39)	missense	possibly damaging	0.93
R4622:Arid1b	UTSW	17	5,045,325 (GRCm39)	unclassified	probably benign
R4723:Arid1b	UTSW	17	5,387,565 (GRCm39)	missense	probably benign	0.01
R4782:Arid1b	UTSW	17	5,389,496 (GRCm39)	missense	probably damaging	1.00
R4799:Arid1b	UTSW	17	5,389,496 (GRCm39)	missense	probably damaging	1.00
R4946:Arid1b	UTSW	17	5,393,118 (GRCm39)	missense	probably damaging	0.99
R5083:Arid1b	UTSW	17	5,364,293 (GRCm39)	missense	possibly damaging	0.54
R5204:Arid1b	UTSW	17	5,393,316 (GRCm39)	missense	probably damaging	0.97
R5347:Arid1b	UTSW	17	5,341,332 (GRCm39)	nonsense	probably null
R5553:Arid1b	UTSW	17	5,364,152 (GRCm39)	missense	probably damaging	1.00
R5713:Arid1b	UTSW	17	5,387,091 (GRCm39)	missense	probably damaging	1.00
R5820:Arid1b	UTSW	17	5,046,529 (GRCm39)	missense	possibly damaging	0.96
R5992:Arid1b	UTSW	17	5,045,231 (GRCm39)	unclassified	probably benign
R6038:Arid1b	UTSW	17	5,386,957 (GRCm39)	missense	probably benign	0.07
R6038:Arid1b	UTSW	17	5,386,957 (GRCm39)	missense	probably benign	0.07
R6153:Arid1b	UTSW	17	5,293,107 (GRCm39)	missense	probably damaging	1.00
R6222:Arid1b	UTSW	17	5,377,922 (GRCm39)	critical splice acceptor site	probably null
R6249:Arid1b	UTSW	17	5,329,636 (GRCm39)	missense	possibly damaging	0.61
R6279:Arid1b	UTSW	17	5,392,274 (GRCm39)	missense	probably damaging	1.00
R6329:Arid1b	UTSW	17	5,387,538 (GRCm39)	nonsense	probably null
R6368:Arid1b	UTSW	17	5,382,808 (GRCm39)	missense	possibly damaging	0.64
R6466:Arid1b	UTSW	17	5,377,953 (GRCm39)	missense	probably damaging	1.00
R6861:Arid1b	UTSW	17	5,377,961 (GRCm39)	missense	possibly damaging	0.93
R7008:Arid1b	UTSW	17	5,341,254 (GRCm39)	missense	probably damaging	1.00
R7270:Arid1b	UTSW	17	5,046,318 (GRCm39)	missense	unknown
R7514:Arid1b	UTSW	17	5,391,989 (GRCm39)	missense	probably benign	0.28
R7519:Arid1b	UTSW	17	5,046,128 (GRCm39)	small insertion	probably benign
R7519:Arid1b	UTSW	17	5,046,119 (GRCm39)	small insertion	probably benign
R7521:Arid1b	UTSW	17	5,392,865 (GRCm39)	missense	probably benign	0.06
R7521:Arid1b	UTSW	17	5,046,119 (GRCm39)	small insertion	probably benign
R7521:Arid1b	UTSW	17	5,046,135 (GRCm39)	small insertion	probably benign
R7616:Arid1b	UTSW	17	5,045,661 (GRCm39)	missense	unknown
R7654:Arid1b	UTSW	17	5,341,360 (GRCm39)	missense	possibly damaging	0.46
R7711:Arid1b	UTSW	17	5,387,095 (GRCm39)	missense	probably benign	0.28
R7828:Arid1b	UTSW	17	5,147,943 (GRCm39)	missense	probably damaging	1.00
R7864:Arid1b	UTSW	17	5,392,530 (GRCm39)	missense	probably damaging	1.00
R7998:Arid1b	UTSW	17	5,377,959 (GRCm39)	missense	probably damaging	1.00
R8105:Arid1b	UTSW	17	5,341,518 (GRCm39)	missense	possibly damaging	0.81
R8260:Arid1b	UTSW	17	5,382,788 (GRCm39)	missense	probably benign	0.03
R8374:Arid1b	UTSW	17	5,392,919 (GRCm39)	missense	possibly damaging	0.95
R8779:Arid1b	UTSW	17	5,391,809 (GRCm39)	missense	probably benign	0.03
R8801:Arid1b	UTSW	17	5,387,103 (GRCm39)	missense	probably benign	0.05
R8894:Arid1b	UTSW	17	5,377,668 (GRCm39)	missense	probably damaging	0.98
R8982:Arid1b	UTSW	17	5,293,316 (GRCm39)	missense	probably damaging	0.98
R9034:Arid1b	UTSW	17	5,387,180 (GRCm39)	missense	probably benign	0.01
R9272:Arid1b	UTSW	17	5,386,879 (GRCm39)	missense	possibly damaging	0.80
R9300:Arid1b	UTSW	17	5,293,274 (GRCm39)	missense	probably damaging	1.00
R9332:Arid1b	UTSW	17	5,045,584 (GRCm39)	missense	unknown
R9481:Arid1b	UTSW	17	5,369,007 (GRCm39)	missense	probably damaging	1.00
R9493:Arid1b	UTSW	17	5,046,423 (GRCm39)	missense	unknown
R9512:Arid1b	UTSW	17	5,391,864 (GRCm39)	missense	probably benign	0.00
R9548:Arid1b	UTSW	17	5,385,262 (GRCm39)	missense	probably damaging	1.00
RF007:Arid1b	UTSW	17	5,045,869 (GRCm39)	small insertion	probably benign
RF008:Arid1b	UTSW	17	5,045,870 (GRCm39)	small insertion	probably benign
RF008:Arid1b	UTSW	17	5,045,869 (GRCm39)	small insertion	probably benign
RF025:Arid1b	UTSW	17	5,045,871 (GRCm39)	small insertion	probably benign
RF025:Arid1b	UTSW	17	5,045,863 (GRCm39)	small insertion	probably benign
RF028:Arid1b	UTSW	17	5,045,873 (GRCm39)	small insertion	probably benign
RF032:Arid1b	UTSW	17	5,045,863 (GRCm39)	small insertion	probably benign
RF033:Arid1b	UTSW	17	5,045,860 (GRCm39)	small insertion	probably benign
RF041:Arid1b	UTSW	17	5,045,870 (GRCm39)	small insertion	probably benign
RF045:Arid1b	UTSW	17	5,045,858 (GRCm39)	small insertion	probably benign
RF046:Arid1b	UTSW	17	5,045,865 (GRCm39)	small insertion	probably benign
RF058:Arid1b	UTSW	17	5,045,858 (GRCm39)	small insertion	probably benign
X0023:Arid1b	UTSW	17	5,392,668 (GRCm39)	missense	probably benign	0.39
X0027:Arid1b	UTSW	17	5,392,647 (GRCm39)	nonsense	probably null
Z1177:Arid1b	UTSW	17	5,046,603 (GRCm39)	missense	possibly damaging	0.70

Predicted Primers

PCR Primer
(F):5'- AGCGGCAAGTTTCCCTTTGG -3'
(R):5'- CGGAAATGTTCGCCAACGTG -3'

Sequencing Primer
(F):5'- TCCCTTTGGAATCCAGCAGG -3'
(R):5'- AACGTGACCAGGGTGTTATCC -3'

Posted On

2016-04-15