Incidental Mutation 'R4916:Urb1'
| ID |
380123 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Urb1
|
| Ensembl Gene |
ENSMUSG00000039929 |
| Gene Name |
URB1 ribosome biogenesis 1 homolog (S. cerevisiae) |
| Synonyms |
5730405K23Rik, 4921511H13Rik |
| MMRRC Submission |
042518-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4916 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
16 |
| Chromosomal Location |
90548415-90607301 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 90580216 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Glutamic Acid
at position 649
(V649E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000114717
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000140920]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000140920
AA Change: V649E
PolyPhen 2
Score 0.999 (Sensitivity: 0.14; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000114717
Gene: ENSMUSG00000039929
AA Change: V649E
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
8 |
20 |
N/A |
INTRINSIC |
|
Pfam:Npa1
|
78 |
396 |
1.5e-86 |
PFAM |
|
low complexity region
|
751 |
761 |
N/A |
INTRINSIC |
|
low complexity region
|
955 |
966 |
N/A |
INTRINSIC |
|
low complexity region
|
1126 |
1137 |
N/A |
INTRINSIC |
|
low complexity region
|
1360 |
1375 |
N/A |
INTRINSIC |
|
Pfam:NopRA1
|
1670 |
1859 |
3.6e-60 |
PFAM |
|
low complexity region
|
2029 |
2040 |
N/A |
INTRINSIC |
|
low complexity region
|
2092 |
2111 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142955
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 95.9%
- 20x: 91.0%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 106 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4930595D18Rik |
G |
A |
12: 111,141,369 (GRCm39) |
Q19* |
probably null |
Het |
| 6030468B19Rik |
T |
A |
11: 117,697,092 (GRCm39) |
C230* |
probably null |
Het |
| Adcy10 |
A |
G |
1: 165,345,815 (GRCm39) |
E288G |
probably damaging |
Het |
| Adnp |
T |
A |
2: 168,029,537 (GRCm39) |
T51S |
possibly damaging |
Het |
| Agap3 |
C |
A |
5: 24,683,011 (GRCm39) |
A464D |
probably damaging |
Het |
| Ago4 |
A |
C |
4: 126,400,635 (GRCm39) |
C693G |
probably damaging |
Het |
| Ahi1 |
A |
G |
10: 20,860,303 (GRCm39) |
R675G |
probably damaging |
Het |
| Amigo1 |
T |
A |
3: 108,094,981 (GRCm39) |
L160Q |
probably damaging |
Het |
| Ankrd35 |
T |
C |
3: 96,591,438 (GRCm39) |
S575P |
probably benign |
Het |
| Ano3 |
T |
A |
2: 110,601,365 (GRCm39) |
T298S |
possibly damaging |
Het |
| Ap2b1 |
T |
G |
11: 83,281,532 (GRCm39) |
F813V |
probably damaging |
Het |
| Aplnr |
T |
G |
2: 84,967,261 (GRCm39) |
F95L |
probably damaging |
Het |
| Apobec2 |
T |
C |
17: 48,730,153 (GRCm39) |
E171G |
probably benign |
Het |
| Ascc1 |
A |
G |
10: 59,840,684 (GRCm39) |
N15S |
probably benign |
Het |
| AY358078 |
T |
A |
14: 52,040,108 (GRCm39) |
Y73N |
unknown |
Het |
| B3gnt8 |
C |
A |
7: 25,328,308 (GRCm39) |
P246Q |
probably damaging |
Het |
| C2cd2l |
T |
C |
9: 44,227,857 (GRCm39) |
Q250R |
probably damaging |
Het |
| Camk2d |
T |
C |
3: 126,577,624 (GRCm39) |
Y180H |
probably damaging |
Het |
| Ccdc170 |
A |
G |
10: 4,468,971 (GRCm39) |
E167G |
probably damaging |
Het |
| Cdcp3 |
T |
A |
7: 130,776,206 (GRCm39) |
|
probably null |
Het |
| Cdyl2 |
A |
G |
8: 117,305,926 (GRCm39) |
M445T |
probably damaging |
Het |
| Clca3a1 |
T |
C |
3: 144,721,605 (GRCm39) |
D322G |
probably benign |
Het |
| Cnot10 |
C |
T |
9: 114,458,202 (GRCm39) |
M101I |
possibly damaging |
Het |
| Cntrl |
C |
T |
2: 35,055,694 (GRCm39) |
T1196M |
probably benign |
Het |
| Cybb |
C |
G |
X: 9,316,989 (GRCm39) |
D246H |
probably benign |
Het |
| Dcaf6 |
T |
C |
1: 165,247,774 (GRCm39) |
D153G |
probably damaging |
Het |
| Dennd2c |
G |
A |
3: 103,039,140 (GRCm39) |
G96E |
probably benign |
Het |
| Dhrs9 |
T |
C |
2: 69,231,752 (GRCm39) |
F304S |
probably damaging |
Het |
| Dmxl1 |
T |
C |
18: 50,010,764 (GRCm39) |
S974P |
probably damaging |
Het |
| Dnah6 |
T |
C |
6: 73,169,659 (GRCm39) |
|
probably benign |
Het |
| Dnah7c |
T |
C |
1: 46,634,168 (GRCm39) |
L1049P |
probably damaging |
Het |
| Dnajc2 |
T |
C |
5: 21,962,338 (GRCm39) |
K621E |
probably damaging |
Het |
| Ehbp1 |
T |
C |
11: 22,096,592 (GRCm39) |
D299G |
probably benign |
Het |
| Erap1 |
A |
G |
13: 74,794,647 (GRCm39) |
E102G |
probably benign |
Het |
| Fasn |
T |
G |
11: 120,707,472 (GRCm39) |
N799T |
probably benign |
Het |
| Fbxl20 |
T |
C |
11: 98,019,186 (GRCm39) |
D22G |
probably damaging |
Het |
| Fgfr1 |
T |
C |
8: 26,053,542 (GRCm39) |
|
probably null |
Het |
| Frzb |
A |
T |
2: 80,276,871 (GRCm39) |
I105N |
probably damaging |
Het |
| Gabrb1 |
T |
A |
5: 72,026,764 (GRCm39) |
F55Y |
probably damaging |
Het |
| Gatd1 |
G |
T |
7: 140,989,010 (GRCm39) |
C216* |
probably null |
Het |
| Gnl2 |
A |
C |
4: 124,937,485 (GRCm39) |
N255T |
probably damaging |
Het |
| Golgb1 |
A |
T |
16: 36,736,480 (GRCm39) |
Q1909L |
probably benign |
Het |
| Gpnmb |
T |
C |
6: 49,028,904 (GRCm39) |
L474P |
probably damaging |
Het |
| H60b |
T |
C |
10: 22,163,115 (GRCm39) |
V230A |
possibly damaging |
Het |
| Hmcn2 |
T |
A |
2: 31,250,992 (GRCm39) |
V818D |
probably damaging |
Het |
| Irag2 |
C |
A |
6: 145,111,027 (GRCm39) |
S277R |
probably damaging |
Het |
| Itprid1 |
C |
T |
6: 55,955,175 (GRCm39) |
P928S |
possibly damaging |
Het |
| Jade2 |
G |
T |
11: 51,707,909 (GRCm39) |
T768K |
probably benign |
Het |
| Kif28 |
T |
C |
1: 179,530,085 (GRCm39) |
H692R |
probably benign |
Het |
| Kmt2b |
T |
C |
7: 30,277,942 (GRCm39) |
N1634S |
probably damaging |
Het |
| Knop1 |
A |
G |
7: 118,445,299 (GRCm39) |
W222R |
probably damaging |
Het |
| Map1b |
T |
C |
13: 99,569,808 (GRCm39) |
D971G |
unknown |
Het |
| Mapk7 |
G |
T |
11: 61,384,475 (GRCm39) |
T77K |
probably damaging |
Het |
| Mcm6 |
A |
G |
1: 128,276,714 (GRCm39) |
L292P |
probably damaging |
Het |
| Megf8 |
T |
C |
7: 25,039,089 (GRCm39) |
L900P |
probably benign |
Het |
| Meis1 |
G |
A |
11: 18,831,776 (GRCm39) |
H421Y |
possibly damaging |
Het |
| Minar2 |
A |
T |
18: 59,205,277 (GRCm39) |
I22F |
probably damaging |
Het |
| Mllt1 |
T |
C |
17: 57,206,813 (GRCm39) |
T344A |
probably benign |
Het |
| Mta1 |
T |
A |
12: 113,100,160 (GRCm39) |
S657T |
probably benign |
Het |
| Mtus1 |
C |
A |
8: 41,453,838 (GRCm39) |
K998N |
probably damaging |
Het |
| Ncdn |
G |
A |
4: 126,643,731 (GRCm39) |
L364F |
possibly damaging |
Het |
| Ndufb7 |
T |
C |
8: 84,297,534 (GRCm39) |
L63P |
probably damaging |
Het |
| Nfix |
T |
C |
8: 85,498,458 (GRCm39) |
I172V |
probably benign |
Het |
| Nos1 |
T |
C |
5: 118,085,635 (GRCm39) |
|
probably null |
Het |
| Nrp1 |
C |
A |
8: 129,229,285 (GRCm39) |
S921* |
probably null |
Het |
| Oma1 |
T |
C |
4: 103,176,727 (GRCm39) |
|
probably null |
Het |
| Or3a1b |
A |
T |
11: 74,012,705 (GRCm39) |
I197F |
probably benign |
Het |
| Or5b106 |
T |
A |
19: 13,123,355 (GRCm39) |
I223L |
possibly damaging |
Het |
| Pcp2 |
T |
A |
8: 3,675,534 (GRCm39) |
|
probably benign |
Het |
| Pdk4 |
T |
A |
6: 5,489,157 (GRCm39) |
H250L |
possibly damaging |
Het |
| Phldb3 |
A |
G |
7: 24,323,716 (GRCm39) |
H449R |
probably benign |
Het |
| Pip4k2c |
T |
C |
10: 127,035,196 (GRCm39) |
T391A |
possibly damaging |
Het |
| Polrmt |
A |
G |
10: 79,582,385 (GRCm39) |
M1T |
probably null |
Het |
| Ppfia2 |
G |
C |
10: 106,597,978 (GRCm39) |
L180F |
probably damaging |
Het |
| Prkcg |
T |
G |
7: 3,378,781 (GRCm39) |
Y624* |
probably null |
Het |
| Psmg2 |
A |
G |
18: 67,781,926 (GRCm39) |
E164G |
probably damaging |
Het |
| Rb1 |
A |
T |
14: 73,454,131 (GRCm39) |
L589H |
probably damaging |
Het |
| Rcvrn |
A |
T |
11: 67,586,591 (GRCm39) |
I117F |
probably damaging |
Het |
| Rere |
T |
A |
4: 150,703,601 (GRCm39) |
W1528R |
probably damaging |
Het |
| Robo2 |
A |
G |
16: 73,695,803 (GRCm39) |
S1447P |
possibly damaging |
Het |
| Scfd2 |
C |
A |
5: 74,623,319 (GRCm39) |
G405W |
probably damaging |
Het |
| Scin |
T |
A |
12: 40,119,373 (GRCm39) |
I552F |
possibly damaging |
Het |
| Serpina3k |
G |
A |
12: 104,309,269 (GRCm39) |
V238M |
probably damaging |
Het |
| Slc1a6 |
G |
A |
10: 78,632,085 (GRCm39) |
V304M |
probably damaging |
Het |
| Slc20a2 |
C |
T |
8: 23,051,020 (GRCm39) |
S351L |
probably damaging |
Het |
| Slc31a2 |
T |
C |
4: 62,215,325 (GRCm39) |
V124A |
probably damaging |
Het |
| Slc38a3 |
T |
C |
9: 107,533,426 (GRCm39) |
N244S |
probably benign |
Het |
| Slc4a1 |
A |
G |
11: 102,243,279 (GRCm39) |
V784A |
probably damaging |
Het |
| Slc6a5 |
T |
C |
7: 49,598,004 (GRCm39) |
F623L |
probably benign |
Het |
| Slf2 |
T |
G |
19: 44,960,100 (GRCm39) |
D1022E |
probably damaging |
Het |
| Slfn8 |
G |
A |
11: 82,907,704 (GRCm39) |
H280Y |
probably damaging |
Het |
| Smpdl3a |
A |
T |
10: 57,677,127 (GRCm39) |
D45V |
probably damaging |
Het |
| Ssh3 |
T |
C |
19: 4,315,170 (GRCm39) |
E342G |
probably damaging |
Het |
| Tacr1 |
A |
T |
6: 82,531,922 (GRCm39) |
I273F |
probably benign |
Het |
| Tfg |
T |
A |
16: 56,514,759 (GRCm39) |
|
probably null |
Het |
| Tmem179 |
A |
G |
12: 112,468,268 (GRCm39) |
L71P |
probably damaging |
Het |
| Tmem63a |
T |
A |
1: 180,794,086 (GRCm39) |
I541N |
probably benign |
Het |
| Traj20 |
G |
A |
14: 54,436,924 (GRCm39) |
|
probably benign |
Het |
| Trappc13 |
A |
T |
13: 104,290,802 (GRCm39) |
|
probably null |
Het |
| Ttn |
A |
T |
2: 76,641,587 (GRCm39) |
L5176Q |
possibly damaging |
Het |
| Tulp1 |
A |
G |
17: 28,578,109 (GRCm39) |
L310P |
probably damaging |
Het |
| Ube3d |
A |
G |
9: 86,304,925 (GRCm39) |
Y306H |
probably damaging |
Het |
| Vps13d |
A |
G |
4: 144,709,963 (GRCm39) |
L4211P |
probably damaging |
Het |
| Vwa5b1 |
T |
A |
4: 138,321,573 (GRCm39) |
I407F |
possibly damaging |
Het |
| Vwce |
G |
T |
19: 10,624,243 (GRCm39) |
C378F |
probably damaging |
Het |
| Zfp791 |
T |
A |
8: 85,837,580 (GRCm39) |
I95L |
probably benign |
Het |
|
| Other mutations in Urb1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00715:Urb1
|
APN |
16 |
90,550,209 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00915:Urb1
|
APN |
16 |
90,575,986 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
IGL01108:Urb1
|
APN |
16 |
90,589,702 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01122:Urb1
|
APN |
16 |
90,601,346 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL01387:Urb1
|
APN |
16 |
90,554,649 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL01484:Urb1
|
APN |
16 |
90,574,448 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01606:Urb1
|
APN |
16 |
90,557,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01989:Urb1
|
APN |
16 |
90,566,474 (GRCm39) |
splice site |
probably benign |
|
|
IGL02516:Urb1
|
APN |
16 |
90,569,583 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
IGL03018:Urb1
|
APN |
16 |
90,585,044 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL03165:Urb1
|
APN |
16 |
90,577,192 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03216:Urb1
|
APN |
16 |
90,585,002 (GRCm39) |
missense |
probably benign |
0.00 |
|
H8562:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
H8786:Urb1
|
UTSW |
16 |
90,566,357 (GRCm39) |
missense |
probably benign |
0.08 |
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0064:Urb1
|
UTSW |
16 |
90,576,028 (GRCm39) |
missense |
probably benign |
|
|
R0359:Urb1
|
UTSW |
16 |
90,588,048 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0386:Urb1
|
UTSW |
16 |
90,593,287 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0508:Urb1
|
UTSW |
16 |
90,580,150 (GRCm39) |
splice site |
probably benign |
|
|
R0517:Urb1
|
UTSW |
16 |
90,574,310 (GRCm39) |
nonsense |
probably null |
|
|
R0704:Urb1
|
UTSW |
16 |
90,573,095 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0755:Urb1
|
UTSW |
16 |
90,576,026 (GRCm39) |
missense |
probably benign |
|
|
R0755:Urb1
|
UTSW |
16 |
90,570,982 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0783:Urb1
|
UTSW |
16 |
90,607,185 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R0833:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0836:Urb1
|
UTSW |
16 |
90,592,336 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0970:Urb1
|
UTSW |
16 |
90,566,335 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1144:Urb1
|
UTSW |
16 |
90,573,206 (GRCm39) |
splice site |
probably null |
|
|
R1344:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1418:Urb1
|
UTSW |
16 |
90,566,354 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1453:Urb1
|
UTSW |
16 |
90,593,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1470:Urb1
|
UTSW |
16 |
90,548,902 (GRCm39) |
missense |
probably benign |
0.34 |
|
R1520:Urb1
|
UTSW |
16 |
90,571,633 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1521:Urb1
|
UTSW |
16 |
90,550,751 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1598:Urb1
|
UTSW |
16 |
90,574,328 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1617:Urb1
|
UTSW |
16 |
90,557,340 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R1625:Urb1
|
UTSW |
16 |
90,570,936 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1640:Urb1
|
UTSW |
16 |
90,569,514 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1664:Urb1
|
UTSW |
16 |
90,584,970 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1672:Urb1
|
UTSW |
16 |
90,584,285 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1694:Urb1
|
UTSW |
16 |
90,563,928 (GRCm39) |
missense |
probably benign |
|
|
R1856:Urb1
|
UTSW |
16 |
90,558,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2001:Urb1
|
UTSW |
16 |
90,559,232 (GRCm39) |
missense |
probably benign |
0.30 |
|
R2196:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2850:Urb1
|
UTSW |
16 |
90,571,144 (GRCm39) |
missense |
probably benign |
0.01 |
|
R3009:Urb1
|
UTSW |
16 |
90,571,686 (GRCm39) |
missense |
probably benign |
0.09 |
|
R3104:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3105:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3106:Urb1
|
UTSW |
16 |
90,592,331 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3160:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3162:Urb1
|
UTSW |
16 |
90,594,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3900:Urb1
|
UTSW |
16 |
90,580,264 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R4014:Urb1
|
UTSW |
16 |
90,566,353 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4036:Urb1
|
UTSW |
16 |
90,584,974 (GRCm39) |
missense |
probably benign |
|
|
R4332:Urb1
|
UTSW |
16 |
90,571,425 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4448:Urb1
|
UTSW |
16 |
90,566,282 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R4581:Urb1
|
UTSW |
16 |
90,585,034 (GRCm39) |
missense |
probably benign |
0.04 |
|
R4593:Urb1
|
UTSW |
16 |
90,584,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4610:Urb1
|
UTSW |
16 |
90,573,159 (GRCm39) |
missense |
probably benign |
0.43 |
|
R4659:Urb1
|
UTSW |
16 |
90,573,017 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4672:Urb1
|
UTSW |
16 |
90,569,522 (GRCm39) |
missense |
probably benign |
|
|
R4681:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4771:Urb1
|
UTSW |
16 |
90,550,406 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4790:Urb1
|
UTSW |
16 |
90,566,443 (GRCm39) |
nonsense |
probably null |
|
|
R4798:Urb1
|
UTSW |
16 |
90,554,715 (GRCm39) |
missense |
probably benign |
0.12 |
|
R4809:Urb1
|
UTSW |
16 |
90,556,730 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4850:Urb1
|
UTSW |
16 |
90,592,302 (GRCm39) |
nonsense |
probably null |
|
|
R4969:Urb1
|
UTSW |
16 |
90,602,299 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5032:Urb1
|
UTSW |
16 |
90,553,059 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5111:Urb1
|
UTSW |
16 |
90,548,905 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5122:Urb1
|
UTSW |
16 |
90,548,983 (GRCm39) |
nonsense |
probably null |
|
|
R5184:Urb1
|
UTSW |
16 |
90,580,162 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5199:Urb1
|
UTSW |
16 |
90,589,636 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5436:Urb1
|
UTSW |
16 |
90,589,650 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5767:Urb1
|
UTSW |
16 |
90,573,051 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5812:Urb1
|
UTSW |
16 |
90,601,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5872:Urb1
|
UTSW |
16 |
90,569,652 (GRCm39) |
nonsense |
probably null |
|
|
R6052:Urb1
|
UTSW |
16 |
90,559,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6063:Urb1
|
UTSW |
16 |
90,585,985 (GRCm39) |
missense |
probably benign |
0.02 |
|
R6065:Urb1
|
UTSW |
16 |
90,600,220 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6181:Urb1
|
UTSW |
16 |
90,575,982 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6268:Urb1
|
UTSW |
16 |
90,550,807 (GRCm39) |
missense |
probably benign |
0.03 |
|
R6429:Urb1
|
UTSW |
16 |
90,559,318 (GRCm39) |
splice site |
probably null |
|
|
R6572:Urb1
|
UTSW |
16 |
90,584,302 (GRCm39) |
missense |
probably benign |
0.37 |
|
R6606:Urb1
|
UTSW |
16 |
90,607,156 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6730:Urb1
|
UTSW |
16 |
90,575,971 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6838:Urb1
|
UTSW |
16 |
90,578,994 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7237:Urb1
|
UTSW |
16 |
90,588,054 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7238:Urb1
|
UTSW |
16 |
90,549,003 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7339:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7341:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7361:Urb1
|
UTSW |
16 |
90,571,656 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7365:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7366:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7440:Urb1
|
UTSW |
16 |
90,584,296 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7530:Urb1
|
UTSW |
16 |
90,558,522 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7553:Urb1
|
UTSW |
16 |
90,589,752 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7557:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7603:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7607:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7609:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7610:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7612:Urb1
|
UTSW |
16 |
90,594,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7613:Urb1
|
UTSW |
16 |
90,569,461 (GRCm39) |
critical splice donor site |
probably benign |
|
|
R7684:Urb1
|
UTSW |
16 |
90,583,006 (GRCm39) |
nonsense |
probably null |
|
|
R8029:Urb1
|
UTSW |
16 |
90,576,040 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8324:Urb1
|
UTSW |
16 |
90,588,078 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8680:Urb1
|
UTSW |
16 |
90,571,513 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8785:Urb1
|
UTSW |
16 |
90,600,311 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8914:Urb1
|
UTSW |
16 |
90,607,122 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8959:Urb1
|
UTSW |
16 |
90,571,005 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9005:Urb1
|
UTSW |
16 |
90,550,678 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9126:Urb1
|
UTSW |
16 |
90,566,290 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R9195:Urb1
|
UTSW |
16 |
90,589,638 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9276:Urb1
|
UTSW |
16 |
90,569,463 (GRCm39) |
splice site |
probably benign |
|
|
R9534:Urb1
|
UTSW |
16 |
90,583,096 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
Z1177:Urb1
|
UTSW |
16 |
90,571,750 (GRCm39) |
missense |
probably benign |
0.05 |
|
Z1177:Urb1
|
UTSW |
16 |
90,550,771 (GRCm39) |
missense |
probably benign |
0.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCTAGTCCTGACTGACTTTCATAG -3'
(R):5'- ATGATGAGCCTGGCAGTGTG -3'
Sequencing Primer
(F):5'- AGTCCTGACTGACTTTCATAGTTCAC -3'
(R):5'- GTAAGTACTGCCCCTTGT -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation