Incidental Mutation 'R0244:Ep300'
| ID |
38015 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Ep300
|
| Ensembl Gene |
ENSMUSG00000055024 |
| Gene Name |
E1A binding protein p300 |
| Synonyms |
p300, KAT3B |
| MMRRC Submission |
038482-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R0244 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
15 |
| Chromosomal Location |
81470329-81536278 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 81524329 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Proline to Serine
at position 1386
(P1386S)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000066789
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000068387]
|
| AlphaFold |
B2RWS6 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000068387
AA Change: P1386S
|
| SMART Domains |
Protein: ENSMUSP00000066789
Gene: ENSMUSG00000055024
AA Change: P1386S
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
18 |
28 |
N/A |
INTRINSIC |
|
low complexity region
|
162 |
178 |
N/A |
INTRINSIC |
|
low complexity region
|
223 |
242 |
N/A |
INTRINSIC |
|
low complexity region
|
296 |
309 |
N/A |
INTRINSIC |
|
ZnF_TAZ
|
333 |
418 |
2.85e-32 |
SMART |
|
low complexity region
|
475 |
488 |
N/A |
INTRINSIC |
|
low complexity region
|
492 |
503 |
N/A |
INTRINSIC |
|
Pfam:KIX
|
567 |
647 |
7.2e-44 |
PFAM |
|
low complexity region
|
722 |
735 |
N/A |
INTRINSIC |
|
low complexity region
|
831 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
852 |
882 |
N/A |
INTRINSIC |
|
low complexity region
|
884 |
920 |
N/A |
INTRINSIC |
|
low complexity region
|
924 |
943 |
N/A |
INTRINSIC |
|
low complexity region
|
1024 |
1039 |
N/A |
INTRINSIC |
|
BROMO
|
1047 |
1157 |
6.36e-42 |
SMART |
|
Blast:KAT11
|
1227 |
1300 |
9e-22 |
BLAST |
|
KAT11
|
1305 |
1610 |
1.19e-140 |
SMART |
|
ZnF_ZZ
|
1663 |
1704 |
2.67e-15 |
SMART |
|
ZnF_TAZ
|
1728 |
1806 |
5.53e-30 |
SMART |
|
low complexity region
|
1810 |
1836 |
N/A |
INTRINSIC |
|
low complexity region
|
1847 |
1881 |
N/A |
INTRINSIC |
|
low complexity region
|
1902 |
1927 |
N/A |
INTRINSIC |
|
low complexity region
|
1962 |
1979 |
N/A |
INTRINSIC |
|
Pfam:Creb_binding
|
1993 |
2099 |
3.5e-37 |
PFAM |
|
low complexity region
|
2146 |
2158 |
N/A |
INTRINSIC |
|
low complexity region
|
2187 |
2203 |
N/A |
INTRINSIC |
|
low complexity region
|
2205 |
2244 |
N/A |
INTRINSIC |
|
low complexity region
|
2254 |
2265 |
N/A |
INTRINSIC |
|
low complexity region
|
2303 |
2346 |
N/A |
INTRINSIC |
|
low complexity region
|
2390 |
2405 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000187776
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000205816
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000206431
|
| Meta Mutation Damage Score |
0.1442 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.5%
|
| Validation Efficiency |
99% (88/89) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes the adenovirus E1A-associated cellular p300 transcriptional co-activator protein. It functions as histone acetyltransferase that regulates transcription via chromatin remodeling and is important in the processes of cell proliferation and differentiation. It mediates cAMP-gene regulation by binding specifically to phosphorylated CREB protein. This gene has also been identified as a co-activator of HIF1A (hypoxia-inducible factor 1 alpha), and thus plays a role in the stimulation of hypoxia-induced genes such as VEGF. Defects in this gene are a cause of Rubinstein-Taybi syndrome and may also play a role in epithelial cancer. [provided by RefSeq, Jul 2008]
PHENOTYPE: Homozygotes for a targeted null mutation exhibit defects of the heart, lung, and small intestine and die at midgestation; heterozygotes also show some embryonic loss. Heterozygotes for an acetyltransferase-negative mutation die by the neonatal period. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 89 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adamdec1 |
A |
T |
14: 68,806,172 (GRCm39) |
C434* |
probably null |
Het |
| Adprhl1 |
A |
G |
8: 13,292,391 (GRCm39) |
|
probably benign |
Het |
| Ago1 |
T |
A |
4: 126,357,499 (GRCm39) |
I59F |
possibly damaging |
Het |
| Arel1 |
T |
C |
12: 84,967,467 (GRCm39) |
T786A |
probably damaging |
Het |
| Arhgap26 |
A |
G |
18: 39,496,184 (GRCm39) |
K117R |
probably benign |
Het |
| Atp6v0b |
C |
T |
4: 117,741,819 (GRCm39) |
G204D |
probably damaging |
Het |
| Bace2 |
T |
A |
16: 97,237,973 (GRCm39) |
|
probably null |
Het |
| Bltp2 |
T |
A |
11: 78,177,317 (GRCm39) |
|
probably null |
Het |
| Camk4 |
G |
A |
18: 33,312,678 (GRCm39) |
|
probably null |
Het |
| Cdh26 |
C |
T |
2: 178,123,425 (GRCm39) |
R675C |
possibly damaging |
Het |
| Cep152 |
T |
C |
2: 125,406,134 (GRCm39) |
E1466G |
probably benign |
Het |
| Ces3b |
T |
C |
8: 105,819,267 (GRCm39) |
F441S |
probably damaging |
Het |
| Cfap52 |
T |
C |
11: 67,817,208 (GRCm39) |
T562A |
possibly damaging |
Het |
| Clca3a2 |
C |
A |
3: 144,519,659 (GRCm39) |
M238I |
possibly damaging |
Het |
| Cntnap5c |
A |
T |
17: 58,409,163 (GRCm39) |
D467V |
probably damaging |
Het |
| Col7a1 |
T |
A |
9: 108,801,252 (GRCm39) |
|
probably null |
Het |
| Cstf1 |
A |
G |
2: 172,219,630 (GRCm39) |
N247S |
possibly damaging |
Het |
| Dffb |
G |
T |
4: 154,059,072 (GRCm39) |
N68K |
probably benign |
Het |
| Dnaaf10 |
T |
C |
11: 17,179,851 (GRCm39) |
L284P |
probably damaging |
Het |
| Duox2 |
C |
T |
2: 122,122,341 (GRCm39) |
G595S |
probably benign |
Het |
| Eftud2 |
T |
A |
11: 102,755,551 (GRCm39) |
I228F |
probably damaging |
Het |
| Elmo3 |
T |
C |
8: 106,035,803 (GRCm39) |
V578A |
probably benign |
Het |
| Elp2 |
A |
G |
18: 24,764,528 (GRCm39) |
D625G |
possibly damaging |
Het |
| Fam120b |
A |
G |
17: 15,637,899 (GRCm39) |
D610G |
probably damaging |
Het |
| Fastk |
A |
T |
5: 24,647,176 (GRCm39) |
|
probably benign |
Het |
| Fbxl6 |
A |
G |
15: 76,421,391 (GRCm39) |
S252P |
probably damaging |
Het |
| Fbxo43 |
T |
C |
15: 36,161,939 (GRCm39) |
K423E |
probably damaging |
Het |
| Filip1 |
T |
A |
9: 79,726,744 (GRCm39) |
E625V |
possibly damaging |
Het |
| Fkbp9 |
T |
A |
6: 56,833,363 (GRCm39) |
Y283* |
probably null |
Het |
| Gigyf2 |
T |
A |
1: 87,306,737 (GRCm39) |
D142E |
possibly damaging |
Het |
| Gm10142 |
T |
C |
10: 77,551,848 (GRCm39) |
|
probably null |
Het |
| Golga5 |
T |
C |
12: 102,442,447 (GRCm39) |
V262A |
probably benign |
Het |
| Hectd4 |
T |
C |
5: 121,467,668 (GRCm39) |
V2539A |
probably benign |
Het |
| Ica1 |
G |
T |
6: 8,653,632 (GRCm39) |
S335* |
probably null |
Het |
| Itga1 |
A |
T |
13: 115,143,433 (GRCm39) |
|
probably benign |
Het |
| Itgb1 |
T |
C |
8: 129,444,166 (GRCm39) |
|
probably benign |
Het |
| Itpr1 |
G |
A |
6: 108,450,550 (GRCm39) |
V1960I |
probably benign |
Het |
| Kcnh4 |
C |
T |
11: 100,637,758 (GRCm39) |
G633E |
probably benign |
Het |
| Kprp |
C |
T |
3: 92,732,718 (GRCm39) |
V111I |
probably benign |
Het |
| Lamc3 |
T |
C |
2: 31,830,733 (GRCm39) |
I1490T |
probably damaging |
Het |
| Lcp1 |
A |
T |
14: 75,464,441 (GRCm39) |
D554V |
possibly damaging |
Het |
| Lgi3 |
A |
G |
14: 70,772,138 (GRCm39) |
T228A |
probably benign |
Het |
| Lipa |
A |
T |
19: 34,478,941 (GRCm39) |
F260I |
probably damaging |
Het |
| Lrriq1 |
C |
T |
10: 103,051,634 (GRCm39) |
E373K |
probably damaging |
Het |
| Map6 |
G |
A |
7: 98,986,043 (GRCm39) |
G649D |
probably benign |
Het |
| Mccc1 |
A |
G |
3: 36,044,196 (GRCm39) |
|
probably null |
Het |
| Mical3 |
A |
T |
6: 120,934,683 (GRCm39) |
S1799T |
probably benign |
Het |
| Mmp23 |
T |
A |
4: 155,736,589 (GRCm39) |
T151S |
probably damaging |
Het |
| Myo1d |
T |
A |
11: 80,565,534 (GRCm39) |
N401I |
probably damaging |
Het |
| Myo9b |
T |
A |
8: 71,774,457 (GRCm39) |
S323T |
probably damaging |
Het |
| Nbn |
G |
T |
4: 15,979,353 (GRCm39) |
W446L |
probably benign |
Het |
| Nedd1 |
A |
T |
10: 92,552,127 (GRCm39) |
|
probably benign |
Het |
| Ngef |
C |
A |
1: 87,415,684 (GRCm39) |
|
probably benign |
Het |
| Nup153 |
A |
T |
13: 46,847,412 (GRCm39) |
N672K |
probably benign |
Het |
| Or10d1b |
T |
A |
9: 39,613,469 (GRCm39) |
I199F |
probably damaging |
Het |
| Or2z8 |
C |
T |
8: 72,812,244 (GRCm39) |
T240M |
probably damaging |
Het |
| Or4e2 |
T |
C |
14: 52,687,969 (GRCm39) |
V33A |
probably benign |
Het |
| Or4f57 |
T |
C |
2: 111,791,361 (GRCm39) |
N19S |
probably benign |
Het |
| Pakap |
T |
G |
4: 57,710,177 (GRCm39) |
V374G |
possibly damaging |
Het |
| Pdlim3 |
C |
A |
8: 46,361,497 (GRCm39) |
|
probably benign |
Het |
| Pmfbp1 |
G |
A |
8: 110,268,305 (GRCm39) |
E951K |
probably damaging |
Het |
| Pop1 |
T |
A |
15: 34,516,037 (GRCm39) |
C548* |
probably null |
Het |
| Ppp1r16a |
C |
T |
15: 76,574,999 (GRCm39) |
|
probably benign |
Het |
| Ptpdc1 |
A |
T |
13: 48,739,456 (GRCm39) |
N658K |
probably benign |
Het |
| Ptprk |
A |
C |
10: 28,082,221 (GRCm39) |
E63D |
possibly damaging |
Het |
| Rtf1 |
C |
T |
2: 119,563,358 (GRCm39) |
R712W |
probably damaging |
Het |
| Samd7 |
A |
C |
3: 30,805,222 (GRCm39) |
T2P |
probably benign |
Het |
| Sft2d1 |
A |
G |
17: 8,538,254 (GRCm39) |
T52A |
probably benign |
Het |
| Slc25a26 |
A |
G |
6: 94,487,814 (GRCm39) |
H91R |
probably damaging |
Het |
| Slc5a4a |
A |
G |
10: 76,024,986 (GRCm39) |
E621G |
possibly damaging |
Het |
| Slf1 |
A |
T |
13: 77,274,751 (GRCm39) |
L28* |
probably null |
Het |
| Snapc1 |
C |
T |
12: 74,021,806 (GRCm39) |
R81C |
probably damaging |
Het |
| Sorcs2 |
G |
A |
5: 36,554,897 (GRCm39) |
|
probably benign |
Het |
| Tacc2 |
T |
C |
7: 130,353,555 (GRCm39) |
|
probably benign |
Het |
| Tas2r140 |
A |
G |
6: 133,032,290 (GRCm39) |
V156A |
possibly damaging |
Het |
| Terf2ip |
C |
A |
8: 112,744,796 (GRCm39) |
T371K |
possibly damaging |
Het |
| Tifa |
C |
T |
3: 127,590,537 (GRCm39) |
L103F |
probably damaging |
Het |
| Tmco3 |
A |
G |
8: 13,342,037 (GRCm39) |
N104D |
probably damaging |
Het |
| Tmem259 |
T |
A |
10: 79,814,797 (GRCm39) |
D240V |
probably damaging |
Het |
| Trim60 |
C |
T |
8: 65,453,700 (GRCm39) |
R183H |
probably benign |
Het |
| Trps1 |
T |
C |
15: 50,528,139 (GRCm39) |
N725D |
probably damaging |
Het |
| Ttn |
C |
T |
2: 76,645,150 (GRCm39) |
V12902M |
probably damaging |
Het |
| Ubxn4 |
G |
A |
1: 128,190,641 (GRCm39) |
E256K |
probably benign |
Het |
| Unc79 |
A |
G |
12: 103,079,150 (GRCm39) |
K1772E |
probably damaging |
Het |
| Vwde |
C |
T |
6: 13,193,125 (GRCm39) |
V405I |
probably benign |
Het |
| Wdr18 |
T |
A |
10: 79,802,242 (GRCm39) |
D290E |
probably damaging |
Het |
| Wwc2 |
G |
A |
8: 48,353,756 (GRCm39) |
A126V |
probably benign |
Het |
| Zfp882 |
A |
T |
8: 72,667,367 (GRCm39) |
I105F |
possibly damaging |
Het |
| Zfp942 |
A |
T |
17: 22,147,553 (GRCm39) |
C359S |
probably benign |
Het |
|
| Other mutations in Ep300 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00236:Ep300
|
APN |
15 |
81,525,619 (GRCm39) |
missense |
unknown |
|
|
IGL01128:Ep300
|
APN |
15 |
81,514,207 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01151:Ep300
|
APN |
15 |
81,507,673 (GRCm39) |
intron |
probably benign |
|
|
IGL01414:Ep300
|
APN |
15 |
81,511,467 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01564:Ep300
|
APN |
15 |
81,516,665 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01875:Ep300
|
APN |
15 |
81,524,224 (GRCm39) |
missense |
unknown |
|
|
IGL01945:Ep300
|
APN |
15 |
81,500,310 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02022:Ep300
|
APN |
15 |
81,495,638 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02115:Ep300
|
APN |
15 |
81,533,019 (GRCm39) |
missense |
unknown |
|
|
IGL02129:Ep300
|
APN |
15 |
81,470,837 (GRCm39) |
missense |
unknown |
|
|
IGL02145:Ep300
|
APN |
15 |
81,485,367 (GRCm39) |
missense |
unknown |
|
|
IGL02149:Ep300
|
APN |
15 |
81,512,621 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02165:Ep300
|
APN |
15 |
81,525,592 (GRCm39) |
missense |
probably benign |
0.39 |
|
IGL02226:Ep300
|
APN |
15 |
81,497,613 (GRCm39) |
missense |
unknown |
|
|
IGL02610:Ep300
|
APN |
15 |
81,485,723 (GRCm39) |
missense |
unknown |
|
|
IGL02731:Ep300
|
APN |
15 |
81,532,615 (GRCm39) |
missense |
unknown |
|
|
IGL03239:Ep300
|
APN |
15 |
81,525,589 (GRCm39) |
missense |
unknown |
|
|
BB001:Ep300
|
UTSW |
15 |
81,533,703 (GRCm39) |
missense |
unknown |
|
|
BB011:Ep300
|
UTSW |
15 |
81,533,703 (GRCm39) |
missense |
unknown |
|
|
R0077:Ep300
|
UTSW |
15 |
81,525,514 (GRCm39) |
missense |
unknown |
|
|
R0145:Ep300
|
UTSW |
15 |
81,500,328 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0390:Ep300
|
UTSW |
15 |
81,524,317 (GRCm39) |
missense |
unknown |
|
|
R0534:Ep300
|
UTSW |
15 |
81,485,097 (GRCm39) |
splice site |
probably benign |
|
|
R0671:Ep300
|
UTSW |
15 |
81,500,335 (GRCm39) |
unclassified |
probably benign |
|
|
R0840:Ep300
|
UTSW |
15 |
81,529,134 (GRCm39) |
missense |
unknown |
|
|
R1166:Ep300
|
UTSW |
15 |
81,514,265 (GRCm39) |
unclassified |
probably benign |
|
|
R1737:Ep300
|
UTSW |
15 |
81,510,548 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1893:Ep300
|
UTSW |
15 |
81,515,847 (GRCm39) |
unclassified |
probably benign |
|
|
R2136:Ep300
|
UTSW |
15 |
81,524,648 (GRCm39) |
missense |
unknown |
|
|
R3427:Ep300
|
UTSW |
15 |
81,485,480 (GRCm39) |
missense |
unknown |
|
|
R3757:Ep300
|
UTSW |
15 |
81,532,790 (GRCm39) |
missense |
unknown |
|
|
R3892:Ep300
|
UTSW |
15 |
81,504,198 (GRCm39) |
unclassified |
probably benign |
|
|
R4554:Ep300
|
UTSW |
15 |
81,485,631 (GRCm39) |
missense |
unknown |
|
|
R4575:Ep300
|
UTSW |
15 |
81,495,611 (GRCm39) |
unclassified |
probably benign |
|
|
R4575:Ep300
|
UTSW |
15 |
81,533,210 (GRCm39) |
missense |
unknown |
|
|
R4577:Ep300
|
UTSW |
15 |
81,495,611 (GRCm39) |
unclassified |
probably benign |
|
|
R4577:Ep300
|
UTSW |
15 |
81,533,210 (GRCm39) |
missense |
unknown |
|
|
R4578:Ep300
|
UTSW |
15 |
81,495,611 (GRCm39) |
unclassified |
probably benign |
|
|
R4578:Ep300
|
UTSW |
15 |
81,533,210 (GRCm39) |
missense |
unknown |
|
|
R5021:Ep300
|
UTSW |
15 |
81,524,224 (GRCm39) |
missense |
unknown |
|
|
R5366:Ep300
|
UTSW |
15 |
81,500,301 (GRCm39) |
missense |
probably benign |
0.24 |
|
R5372:Ep300
|
UTSW |
15 |
81,521,031 (GRCm39) |
missense |
unknown |
|
|
R5393:Ep300
|
UTSW |
15 |
81,515,819 (GRCm39) |
unclassified |
probably benign |
|
|
R5410:Ep300
|
UTSW |
15 |
81,533,055 (GRCm39) |
missense |
unknown |
|
|
R5571:Ep300
|
UTSW |
15 |
81,527,418 (GRCm39) |
intron |
probably benign |
|
|
R5701:Ep300
|
UTSW |
15 |
81,485,696 (GRCm39) |
missense |
unknown |
|
|
R5772:Ep300
|
UTSW |
15 |
81,524,115 (GRCm39) |
intron |
probably benign |
|
|
R5825:Ep300
|
UTSW |
15 |
81,495,673 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5917:Ep300
|
UTSW |
15 |
81,512,808 (GRCm39) |
unclassified |
probably benign |
|
|
R5991:Ep300
|
UTSW |
15 |
81,532,667 (GRCm39) |
missense |
unknown |
|
|
R6019:Ep300
|
UTSW |
15 |
81,525,583 (GRCm39) |
missense |
unknown |
|
|
R6144:Ep300
|
UTSW |
15 |
81,485,435 (GRCm39) |
missense |
unknown |
|
|
R6291:Ep300
|
UTSW |
15 |
81,532,708 (GRCm39) |
missense |
unknown |
|
|
R6292:Ep300
|
UTSW |
15 |
81,500,935 (GRCm39) |
unclassified |
probably benign |
|
|
R6599:Ep300
|
UTSW |
15 |
81,470,914 (GRCm39) |
missense |
unknown |
|
|
R6804:Ep300
|
UTSW |
15 |
81,525,512 (GRCm39) |
nonsense |
probably null |
|
|
R6925:Ep300
|
UTSW |
15 |
81,534,182 (GRCm39) |
missense |
probably benign |
0.32 |
|
R7327:Ep300
|
UTSW |
15 |
81,511,515 (GRCm39) |
missense |
unknown |
|
|
R7378:Ep300
|
UTSW |
15 |
81,534,746 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7388:Ep300
|
UTSW |
15 |
81,532,567 (GRCm39) |
missense |
unknown |
|
|
R7419:Ep300
|
UTSW |
15 |
81,532,715 (GRCm39) |
missense |
unknown |
|
|
R7498:Ep300
|
UTSW |
15 |
81,524,044 (GRCm39) |
missense |
unknown |
|
|
R7584:Ep300
|
UTSW |
15 |
81,512,627 (GRCm39) |
missense |
unknown |
|
|
R7605:Ep300
|
UTSW |
15 |
81,505,353 (GRCm39) |
missense |
unknown |
|
|
R7619:Ep300
|
UTSW |
15 |
81,492,399 (GRCm39) |
missense |
unknown |
|
|
R7699:Ep300
|
UTSW |
15 |
81,470,594 (GRCm39) |
start gained |
probably benign |
|
|
R7763:Ep300
|
UTSW |
15 |
81,470,784 (GRCm39) |
start gained |
probably benign |
|
|
R7775:Ep300
|
UTSW |
15 |
81,470,887 (GRCm39) |
missense |
unknown |
|
|
R7778:Ep300
|
UTSW |
15 |
81,470,887 (GRCm39) |
missense |
unknown |
|
|
R7862:Ep300
|
UTSW |
15 |
81,534,954 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7924:Ep300
|
UTSW |
15 |
81,533,703 (GRCm39) |
missense |
unknown |
|
|
R8155:Ep300
|
UTSW |
15 |
81,505,269 (GRCm39) |
missense |
unknown |
|
|
R8259:Ep300
|
UTSW |
15 |
81,523,218 (GRCm39) |
missense |
unknown |
|
|
R8276:Ep300
|
UTSW |
15 |
81,534,229 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R8331:Ep300
|
UTSW |
15 |
81,485,411 (GRCm39) |
missense |
unknown |
|
|
R8554:Ep300
|
UTSW |
15 |
81,523,228 (GRCm39) |
missense |
unknown |
|
|
R9019:Ep300
|
UTSW |
15 |
81,532,730 (GRCm39) |
missense |
unknown |
|
|
R9128:Ep300
|
UTSW |
15 |
81,533,946 (GRCm39) |
missense |
unknown |
|
|
R9379:Ep300
|
UTSW |
15 |
81,532,760 (GRCm39) |
missense |
unknown |
|
|
R9380:Ep300
|
UTSW |
15 |
81,500,245 (GRCm39) |
missense |
unknown |
|
|
R9484:Ep300
|
UTSW |
15 |
81,521,026 (GRCm39) |
missense |
unknown |
|
|
R9659:Ep300
|
UTSW |
15 |
81,505,273 (GRCm39) |
missense |
unknown |
|
|
R9690:Ep300
|
UTSW |
15 |
81,520,396 (GRCm39) |
missense |
unknown |
|
|
R9721:Ep300
|
UTSW |
15 |
81,492,516 (GRCm39) |
missense |
unknown |
|
|
RF020:Ep300
|
UTSW |
15 |
81,470,772 (GRCm39) |
start gained |
probably benign |
|
|
Z1177:Ep300
|
UTSW |
15 |
81,514,298 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TTGCCATCTACCAGACTTGGGACC -3'
(R):5'- TCCGCAAGCATTTAGGACGGAAG -3'
Sequencing Primer
(F):5'- CTGAATCAGGAGAGGTCACTGTTC -3'
(R):5'- CGAGGTAAGATATGTATACCCTCC -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation