Mutagenetix > Incidental Mutation

Incidental Mutation 'R4937:Zfp646'

380473

Institutional Source

Beutler Lab

Gene Symbol

Zfp646

Ensembl Gene

ENSMUSG00000049739

Gene Name

zinc finger protein 646

Synonyms

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.251) question?

Stock #

R4937 (G1)

Quality Score

225

Status

Not validated

Chromosome

Chromosomal Location

127476081-127485168 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

C to T at 127478354 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Alanine to Valine at position 177 (A177V)

Ref Sequence

ENSEMBL: ENSMUSP00000115499 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000050383] [ENSMUST00000054415] [ENSMUST00000106261] [ENSMUST00000106262] [ENSMUST00000106263] [ENSMUST00000131000] [ENSMUST00000144721]

AlphaFold

Q6NV66

Predicted Effect

probably benign
Transcript: ENSMUST00000050383
AA Change: A177V

PolyPhen 2 Score 0.002 (Sensitivity: 0.99; Specificity: 0.30)

SMART Domains

Protein: ENSMUSP00000052641
Gene: ENSMUSG00000049739
AA Change: A177V

Domain	Start	End	E-Value	Type
ZnF_C2H2	8	31	1.36e-2	SMART
ZnF_C2H2	67	89	5.29e-5	SMART
ZnF_C2H2	231	253	3.21e-4	SMART
ZnF_C2H2	258	280	9.58e-3	SMART
ZnF_C2H2	286	308	2.24e-3	SMART
low complexity region	345	362	N/A	INTRINSIC
ZnF_C2H2	366	388	5.42e-2	SMART
ZnF_C2H2	393	415	8.34e-3	SMART
ZnF_C2H2	457	479	5.9e-3	SMART
ZnF_C2H2	484	506	4.87e-4	SMART
ZnF_C2H2	566	588	2.32e-1	SMART
ZnF_C2H2	606	628	6.32e-3	SMART
ZnF_C2H2	633	655	1.53e-1	SMART
low complexity region	737	750	N/A	INTRINSIC
low complexity region	786	797	N/A	INTRINSIC
ZnF_C2H2	806	828	2.17e-1	SMART
ZnF_C2H2	833	855	3.69e-4	SMART
ZnF_C2H2	866	889	1.16e-1	SMART
low complexity region	890	911	N/A	INTRINSIC
ZnF_C2H2	941	961	9.31e1	SMART
ZnF_C2H2	1035	1057	1.95e-3	SMART
ZnF_C2H2	1062	1084	3.39e-3	SMART
low complexity region	1149	1163	N/A	INTRINSIC
ZnF_C2H2	1170	1192	1.58e-3	SMART
ZnF_C2H2	1197	1219	5.42e-2	SMART
ZnF_C2H2	1225	1247	3.69e-4	SMART
ZnF_C2H2	1266	1286	5.12e1	SMART
ZnF_C2H2	1293	1315	3.69e-4	SMART
ZnF_C2H2	1333	1355	3.11e-2	SMART
ZnF_C2H2	1550	1572	5.9e-3	SMART
ZnF_C2H2	1640	1662	1.08e-1	SMART
ZnF_C2H2	1667	1689	4.11e-2	SMART
ZnF_C2H2	1695	1717	4.11e-2	SMART
ZnF_C2H2	1724	1746	1.45e-2	SMART
low complexity region	1751	1764	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000054415

SMART Domains

Protein: ENSMUSP00000056105
Gene: ENSMUSG00000049728

Domain	Start	End	E-Value	Type
ZnF_C2H2	22	44	7.67e-2	SMART
ZnF_C2H2	84	106	9.44e-2	SMART
ZnF_C2H2	112	134	3.63e-3	SMART
ZnF_C2H2	140	162	2.36e-2	SMART
ZnF_C2H2	168	190	1.98e-4	SMART
ZnF_C2H2	196	218	2.91e-2	SMART
ZnF_C2H2	224	246	1.26e-2	SMART
ZnF_C2H2	252	274	5.21e-4	SMART
ZnF_C2H2	280	302	2.57e-3	SMART
ZnF_C2H2	308	330	5.59e-4	SMART
ZnF_C2H2	336	358	1.79e-2	SMART
ZnF_C2H2	364	386	7.9e-4	SMART
ZnF_C2H2	392	414	5.5e-3	SMART
low complexity region	428	470	N/A	INTRINSIC
ZnF_C2H2	516	538	3.63e-3	SMART
ZnF_C2H2	544	566	1.3e-4	SMART
ZnF_C2H2	572	594	5.59e-4	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000106261

SMART Domains

Protein: ENSMUSP00000101868
Gene: ENSMUSG00000049728

Domain	Start	End	E-Value	Type
ZnF_C2H2	22	44	7.67e-2	SMART
ZnF_C2H2	84	106	9.44e-2	SMART
ZnF_C2H2	112	134	3.63e-3	SMART
ZnF_C2H2	140	162	2.36e-2	SMART
ZnF_C2H2	168	190	1.98e-4	SMART
ZnF_C2H2	196	218	2.91e-2	SMART
ZnF_C2H2	224	246	1.26e-2	SMART
ZnF_C2H2	252	274	5.21e-4	SMART
ZnF_C2H2	280	302	2.57e-3	SMART
ZnF_C2H2	308	330	5.59e-4	SMART
ZnF_C2H2	336	358	1.79e-2	SMART
ZnF_C2H2	364	386	7.9e-4	SMART
ZnF_C2H2	392	414	5.5e-3	SMART
low complexity region	428	470	N/A	INTRINSIC
ZnF_C2H2	516	538	3.63e-3	SMART
ZnF_C2H2	544	566	1.3e-4	SMART
ZnF_C2H2	572	594	5.59e-4	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000106262

SMART Domains

Protein: ENSMUSP00000101869
Gene: ENSMUSG00000049728

Domain	Start	End	E-Value	Type
ZnF_C2H2	22	44	7.67e-2	SMART
ZnF_C2H2	84	106	9.44e-2	SMART
ZnF_C2H2	112	134	3.63e-3	SMART
ZnF_C2H2	140	162	2.36e-2	SMART
ZnF_C2H2	168	190	1.98e-4	SMART
ZnF_C2H2	196	218	2.91e-2	SMART
ZnF_C2H2	224	246	1.26e-2	SMART
ZnF_C2H2	252	274	5.21e-4	SMART
ZnF_C2H2	280	302	2.57e-3	SMART
ZnF_C2H2	308	330	5.59e-4	SMART
ZnF_C2H2	336	358	1.79e-2	SMART
ZnF_C2H2	364	386	7.9e-4	SMART
ZnF_C2H2	392	414	5.5e-3	SMART
low complexity region	428	470	N/A	INTRINSIC
ZnF_C2H2	516	538	3.63e-3	SMART
ZnF_C2H2	544	566	1.3e-4	SMART
ZnF_C2H2	572	594	5.59e-4	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000106263

SMART Domains

Protein: ENSMUSP00000101870
Gene: ENSMUSG00000049728

Domain	Start	End	E-Value	Type
ZnF_C2H2	22	44	7.67e-2	SMART
ZnF_C2H2	84	106	9.44e-2	SMART
ZnF_C2H2	112	134	3.63e-3	SMART
ZnF_C2H2	140	162	2.36e-2	SMART
ZnF_C2H2	168	190	1.98e-4	SMART
ZnF_C2H2	196	218	2.91e-2	SMART
ZnF_C2H2	224	246	1.26e-2	SMART
ZnF_C2H2	252	274	5.21e-4	SMART
ZnF_C2H2	280	302	2.57e-3	SMART
ZnF_C2H2	308	330	5.59e-4	SMART
ZnF_C2H2	336	358	1.79e-2	SMART
ZnF_C2H2	364	386	7.9e-4	SMART
ZnF_C2H2	392	414	5.5e-3	SMART
low complexity region	428	470	N/A	INTRINSIC
ZnF_C2H2	516	538	3.63e-3	SMART
ZnF_C2H2	544	566	1.3e-4	SMART
ZnF_C2H2	572	594	5.59e-4	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000131000
AA Change: A177V

PolyPhen 2 Score 0.014 (Sensitivity: 0.96; Specificity: 0.79)

SMART Domains

Protein: ENSMUSP00000115499
Gene: ENSMUSG00000049739
AA Change: A177V

Domain	Start	End	E-Value	Type
ZnF_C2H2	8	31	1.36e-2	SMART
ZnF_C2H2	67	89	5.29e-5	SMART
ZnF_C2H2	231	253	3.21e-4	SMART
ZnF_C2H2	258	280	9.58e-3	SMART
ZnF_C2H2	286	308	2.24e-3	SMART
low complexity region	345	362	N/A	INTRINSIC
ZnF_C2H2	366	388	5.42e-2	SMART
ZnF_C2H2	393	415	8.34e-3	SMART
ZnF_C2H2	457	479	5.9e-3	SMART
ZnF_C2H2	484	506	4.87e-4	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000144721

SMART Domains

Protein: ENSMUSP00000116730
Gene: ENSMUSG00000049728

Domain	Start	End	E-Value	Type
ZnF_C2H2	22	44	7.67e-2	SMART
ZnF_C2H2	84	106	9.44e-2	SMART

Predicted Effect

probably benign
Transcript: ENSMUST00000206340

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000150961

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000205364

Coding Region Coverage

1x: 98.9%
3x: 98.0%
10x: 95.1%
20x: 88.3%

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 102 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930522L14Rik	A	G	5: 109,884,067 (GRCm39)	F597S	probably benign	Het
Aasdh	C	A	5: 77,036,501 (GRCm39)	E347*	probably null	Het
Abca16	G	T	7: 120,126,309 (GRCm39)	C1155F	probably damaging	Het
Adam26a	T	C	8: 44,021,918 (GRCm39)	D524G	probably damaging	Het
Adamts20	G	C	15: 94,277,656 (GRCm39)	H269D	probably benign	Het
Akap9	T	A	5: 4,100,145 (GRCm39)		probably null	Het
Akt3	T	C	1: 176,877,693 (GRCm39)	I358M	possibly damaging	Het
Aldh9a1	G	T	1: 167,189,376 (GRCm39)	A375S	probably damaging	Het
Alg2	A	G	4: 47,473,974 (GRCm39)	S105P	probably benign	Het
Amph	A	G	13: 19,288,515 (GRCm39)	T335A	probably damaging	Het
Ank2	C	T	3: 126,756,050 (GRCm39)	V1056M	probably damaging	Het
Apoh	A	G	11: 108,298,204 (GRCm39)	D168G	probably benign	Het
Arfgef3	C	T	10: 18,465,454 (GRCm39)	A2130T	probably damaging	Het
Arhgap30	A	G	1: 171,230,897 (GRCm39)	D218G	probably benign	Het
Ascc3	C	T	10: 50,699,894 (GRCm39)	P1906S	probably damaging	Het
Atp11b	T	G	3: 35,861,157 (GRCm39)		probably null	Het
B4galnt2	A	G	11: 95,759,255 (GRCm39)	V343A	probably damaging	Het
Barhl1	T	C	2: 28,799,785 (GRCm39)	Y280C	probably damaging	Het
Bcar1	A	T	8: 112,447,669 (GRCm39)	Y103N	probably damaging	Het
Bid	A	G	6: 120,872,707 (GRCm39)	I150T	probably benign	Het
Ccdc171	T	C	4: 83,467,876 (GRCm39)	S74P	probably damaging	Het
Ccni	A	T	5: 93,336,113 (GRCm39)		probably null	Het
Cct8l1	A	G	5: 25,721,891 (GRCm39)	E202G	probably benign	Het
Cd200r3	A	G	16: 44,774,622 (GRCm39)	K212E	probably benign	Het
Cdh19	A	G	1: 110,817,694 (GRCm39)	S683P	probably damaging	Het
Ces2b	A	T	8: 105,559,413 (GRCm39)	H93L	probably benign	Het
Cimip2b	T	A	4: 43,427,514 (GRCm39)	Q270L	possibly damaging	Het
Clec4a1	G	A	6: 122,907,654 (GRCm39)	C114Y	probably damaging	Het
Dcc	G	T	18: 71,675,320 (GRCm39)	S636*	probably null	Het
Dcdc2c	T	C	12: 28,580,472 (GRCm39)	D187G	possibly damaging	Het
Dgkb	G	T	12: 38,164,657 (GRCm39)	E150*	probably null	Het
Dhx30	A	G	9: 109,915,029 (GRCm39)	L884P	probably damaging	Het
Dmwd	T	G	7: 18,815,228 (GRCm39)		probably null	Het
Dnah17	T	A	11: 117,932,980 (GRCm39)	N3593Y	probably damaging	Het
Dnm2	G	A	9: 21,392,633 (GRCm39)	S447N	probably benign	Het
Elk4	G	A	1: 131,945,419 (GRCm39)	G99D	probably damaging	Het
Entpd1	A	T	19: 40,727,965 (GRCm39)		probably benign	Het
Fam114a1	T	A	5: 65,137,070 (GRCm39)	D4E	probably damaging	Het
Fbln2	A	G	6: 91,241,681 (GRCm39)	D754G	probably damaging	Het
Fhip2a	T	C	19: 57,367,069 (GRCm39)	V204A	probably benign	Het
Foxred2	T	C	15: 77,840,035 (GRCm39)	N85S	probably damaging	Het
Fut9	A	G	4: 25,799,591 (GRCm39)		probably benign	Het
Gm1818	G	A	12: 48,606,607 (GRCm39)		noncoding transcript	Het
Gm4894	C	A	9: 49,190,000 (GRCm39)	Q92K	unknown	Het
Gpx2	T	C	12: 76,839,574 (GRCm39)	I141M	probably benign	Het
Gusb	T	C	5: 130,024,326 (GRCm39)	T476A	probably damaging	Het
Hmmr	G	A	11: 40,612,667 (GRCm39)	T180I	possibly damaging	Het
Itgbl1	T	C	14: 124,210,780 (GRCm39)	Y493H	probably benign	Het
Klhdc9	G	T	1: 171,187,951 (GRCm39)	C93*	probably null	Het
Ldaf1	T	C	7: 119,715,535 (GRCm39)	S120P	probably damaging	Het
Lpar3	A	G	3: 145,990,506 (GRCm39)	K275E	probably damaging	Het
Lrp1b	A	G	2: 40,692,897 (GRCm39)		probably null	Het
Lrrc63	C	T	14: 75,322,389 (GRCm39)	G572S	probably damaging	Het
Mapk11	A	T	15: 89,030,685 (GRCm39)	D98E	probably benign	Het
Mgat4f	T	A	1: 134,317,714 (GRCm39)	M162K	probably benign	Het
Net1	G	A	13: 3,934,905 (GRCm39)	R374W	probably damaging	Het
Nlrp4g	T	A	9: 124,354,005 (GRCm38)		noncoding transcript	Het
Nrap	T	A	19: 56,335,652 (GRCm39)	Y923F	probably damaging	Het
Or13a20	T	A	7: 140,232,534 (GRCm39)	M214K	probably benign	Het
Or4c108	T	A	2: 88,803,834 (GRCm39)	I134F	probably damaging	Het
Or6c215	A	T	10: 129,637,932 (GRCm39)	V154E	probably benign	Het
Plxnc1	A	G	10: 94,677,335 (GRCm39)	V964A	probably damaging	Het
Pmfbp1	A	G	8: 110,262,498 (GRCm39)	I731V	probably benign	Het
Polq	T	A	16: 36,848,274 (GRCm39)	S294T	probably benign	Het
Pomgnt2	T	C	9: 121,811,620 (GRCm39)	D387G	probably benign	Het
Pramel25	T	C	4: 143,520,407 (GRCm39)	V53A	possibly damaging	Het
Prmt2	G	A	10: 76,056,842 (GRCm39)	T227I	probably damaging	Het
Psmd1	T	A	1: 86,010,947 (GRCm39)	F341I	probably damaging	Het
Ptpn23	T	C	9: 110,221,806 (GRCm39)	M127V	probably benign	Het
Ptprc	A	G	1: 138,017,238 (GRCm39)	F483L	probably damaging	Het
Rab35	A	C	5: 115,778,147 (GRCm39)	I38L	probably damaging	Het
Rapgef6	A	G	11: 54,548,143 (GRCm39)	T486A	probably damaging	Het
Rgl3	A	T	9: 21,899,004 (GRCm39)	C68*	probably null	Het
Rilpl1	T	C	5: 124,653,594 (GRCm39)	E189G	possibly damaging	Het
Rnf217	T	C	10: 31,393,520 (GRCm39)	I354V	probably benign	Het
Rspo3	T	C	10: 29,382,524 (GRCm39)	D50G	probably damaging	Het
Sbno1	A	G	5: 124,512,672 (GRCm39)	S1366P	possibly damaging	Het
Sema3c	A	G	5: 17,899,684 (GRCm39)	D392G	probably benign	Het
Serpinb9e	A	T	13: 33,436,935 (GRCm39)	Y85F	probably benign	Het
Shprh	C	T	10: 11,032,863 (GRCm39)	T283I	probably benign	Het
Sipa1l1	T	C	12: 82,388,103 (GRCm39)	S110P	probably benign	Het
Slc16a12	T	A	19: 34,652,643 (GRCm39)	I168F	probably damaging	Het
Slc23a3	A	G	1: 75,109,268 (GRCm39)	S221P	probably damaging	Het
Slc35b3	A	T	13: 39,116,887 (GRCm39)	I366K	possibly damaging	Het
Slc44a5	T	C	3: 153,949,252 (GRCm39)		probably null	Het
Slc5a12	A	T	2: 110,450,753 (GRCm39)	D316V	probably damaging	Het
Ssr3	A	G	3: 65,299,874 (GRCm39)	S29P	probably damaging	Het
Taf2	G	A	15: 54,890,619 (GRCm39)	Q1055*	probably null	Het
Them6	A	T	15: 74,593,367 (GRCm39)	D75V	probably damaging	Het
Tom1l2	A	G	11: 60,149,744 (GRCm39)	S239P	probably damaging	Het
Tspear	A	G	10: 77,710,877 (GRCm39)	T500A	probably damaging	Het
Tubgcp6	G	A	15: 88,985,752 (GRCm39)	A1487V	probably damaging	Het
Uba7	G	A	9: 107,856,190 (GRCm39)	V522I	possibly damaging	Het
Virma	C	A	4: 11,521,147 (GRCm39)	C901*	probably null	Het
Vmn1r172	A	T	7: 23,359,312 (GRCm39)	I66F	possibly damaging	Het
Vmn2r82	A	T	10: 79,215,010 (GRCm39)	Y331F	probably benign	Het
Wdr55	G	A	18: 36,895,451 (GRCm39)	V143I	probably benign	Het
Zbtb49	A	T	5: 38,371,307 (GRCm39)	D191E	possibly damaging	Het
Zfhx4	A	G	3: 5,307,071 (GRCm39)	H99R	probably damaging	Het
Zfp1005	C	T	2: 150,110,680 (GRCm39)	H457Y	unknown	Het
Zfp560	C	T	9: 20,259,263 (GRCm39)	C533Y	probably damaging	Het
Zfp653	C	T	9: 21,967,074 (GRCm39)	E604K	probably damaging	Het

Other mutations in Zfp646

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00930:Zfp646	APN	7	127,478,302 (GRCm39)	missense	possibly damaging	0.91
IGL01669:Zfp646	APN	7	127,478,137 (GRCm39)	missense	probably benign
IGL02571:Zfp646	APN	7	127,478,584 (GRCm39)	missense	probably damaging	1.00
R0009:Zfp646	UTSW	7	127,479,903 (GRCm39)	missense	probably damaging	0.96
R0084:Zfp646	UTSW	7	127,480,476 (GRCm39)	missense	possibly damaging	0.86
R0140:Zfp646	UTSW	7	127,482,678 (GRCm39)	missense	probably benign	0.41
R0394:Zfp646	UTSW	7	127,482,434 (GRCm39)	missense	possibly damaging	0.85
R0571:Zfp646	UTSW	7	127,481,138 (GRCm39)	missense	probably damaging	0.96
R0924:Zfp646	UTSW	7	127,482,982 (GRCm39)	nonsense	probably null
R0930:Zfp646	UTSW	7	127,482,982 (GRCm39)	nonsense	probably null
R1219:Zfp646	UTSW	7	127,482,292 (GRCm39)	missense	probably benign
R1221:Zfp646	UTSW	7	127,482,292 (GRCm39)	missense	probably benign
R1351:Zfp646	UTSW	7	127,482,683 (GRCm39)	missense	probably benign
R1370:Zfp646	UTSW	7	127,479,036 (GRCm39)	missense	probably damaging	1.00
R1503:Zfp646	UTSW	7	127,479,308 (GRCm39)	missense	probably damaging	1.00
R1605:Zfp646	UTSW	7	127,479,359 (GRCm39)	splice site	probably null
R1817:Zfp646	UTSW	7	127,482,292 (GRCm39)	missense	probably benign
R1818:Zfp646	UTSW	7	127,482,292 (GRCm39)	missense	probably benign
R1819:Zfp646	UTSW	7	127,482,292 (GRCm39)	missense	probably benign
R1838:Zfp646	UTSW	7	127,478,911 (GRCm39)	missense	probably damaging	1.00
R1870:Zfp646	UTSW	7	127,483,021 (GRCm39)	missense	possibly damaging	0.85
R2100:Zfp646	UTSW	7	127,481,359 (GRCm39)	missense	probably damaging	1.00
R2763:Zfp646	UTSW	7	127,479,210 (GRCm39)	nonsense	probably null
R4346:Zfp646	UTSW	7	127,478,681 (GRCm39)	missense	probably damaging	1.00
R4770:Zfp646	UTSW	7	127,482,649 (GRCm39)	missense	possibly damaging	0.83
R4824:Zfp646	UTSW	7	127,482,907 (GRCm39)	missense	probably benign	0.00
R4936:Zfp646	UTSW	7	127,480,933 (GRCm39)	missense	possibly damaging	0.93
R5062:Zfp646	UTSW	7	127,479,671 (GRCm39)	missense	probably damaging	0.99
R5424:Zfp646	UTSW	7	127,481,875 (GRCm39)	missense	possibly damaging	0.72
R5610:Zfp646	UTSW	7	127,478,530 (GRCm39)	missense	probably damaging	1.00
R5729:Zfp646	UTSW	7	127,484,626 (GRCm39)	missense	probably damaging	0.99
R6112:Zfp646	UTSW	7	127,478,190 (GRCm39)	missense	possibly damaging	0.71
R6161:Zfp646	UTSW	7	127,477,897 (GRCm39)	missense	probably damaging	1.00
R6310:Zfp646	UTSW	7	127,483,079 (GRCm39)	missense	probably benign	0.13
R6331:Zfp646	UTSW	7	127,482,853 (GRCm39)	missense	probably damaging	0.99
R6436:Zfp646	UTSW	7	127,479,113 (GRCm39)	missense	probably benign	0.00
R6814:Zfp646	UTSW	7	127,482,505 (GRCm39)	missense	probably benign	0.17
R6872:Zfp646	UTSW	7	127,482,505 (GRCm39)	missense	probably benign	0.17
R6903:Zfp646	UTSW	7	127,479,892 (GRCm39)	missense	possibly damaging	0.91
R7018:Zfp646	UTSW	7	127,481,494 (GRCm39)	missense	probably benign
R7049:Zfp646	UTSW	7	127,479,199 (GRCm39)	missense	possibly damaging	0.93
R7121:Zfp646	UTSW	7	127,478,944 (GRCm39)	missense	possibly damaging	0.95
R7405:Zfp646	UTSW	7	127,477,968 (GRCm39)	nonsense	probably null
R8345:Zfp646	UTSW	7	127,483,082 (GRCm39)	missense	probably benign	0.12
R8545:Zfp646	UTSW	7	127,484,662 (GRCm39)	missense	probably benign
R8909:Zfp646	UTSW	7	127,478,515 (GRCm39)	missense	probably damaging	0.99
R8983:Zfp646	UTSW	7	127,480,777 (GRCm39)	missense	probably benign
R9001:Zfp646	UTSW	7	127,478,856 (GRCm39)	missense	probably damaging	0.96
R9018:Zfp646	UTSW	7	127,478,243 (GRCm39)	missense	probably benign
R9118:Zfp646	UTSW	7	127,480,810 (GRCm39)	missense
R9414:Zfp646	UTSW	7	127,481,050 (GRCm39)	missense	probably damaging	0.99
Z1177:Zfp646	UTSW	7	127,479,804 (GRCm39)	missense	probably benign	0.12

Predicted Primers

PCR Primer
(F):5'- AGTGAGACCATGGCTACTGACTC -3'
(R):5'- CGGCATGCTTATAGGTCTTCC -3'

Sequencing Primer
(F):5'- TACTGACTCCTGGGGTCAGAG -3'
(R):5'- ATGCTTATAGGTCTTCCCGCAC -3'

Posted On

2016-04-15