Incidental Mutation 'R4932:Dip2c'
| ID |
380666 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dip2c
|
| Ensembl Gene |
ENSMUSG00000048264 |
| Gene Name |
disco interacting protein 2 homolog C |
| Synonyms |
2900024P20Rik |
| Accession Numbers |
|
| Essential gene? |
Possibly essential
(E-score: 0.590)
|
| Stock # |
R4932 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
13 |
| Chromosomal Location |
9326564-9718964 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 9674008 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Lysine to Glutamic Acid
at position 1091
(K1091E)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000131238
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000166299]
[ENSMUST00000169960]
[ENSMUST00000174552]
|
| AlphaFold |
E9PWR4 |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000157741
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000166299
AA Change: K1121E
PolyPhen 2
Score 0.697 (Sensitivity: 0.86; Specificity: 0.92)
|
| SMART Domains |
Protein: ENSMUSP00000126827
Gene: ENSMUSG00000048264
AA Change: K1121E
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
801 |
3.6e-23 |
PFAM |
|
Pfam:AMP-binding
|
977 |
1451 |
1.5e-72 |
PFAM |
|
low complexity region
|
1514 |
1526 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000169960
AA Change: K1091E
PolyPhen 2
Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000131238
Gene: ENSMUSG00000048264
AA Change: K1091E
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
176 |
3.02e-37 |
SMART |
|
low complexity region
|
226 |
243 |
N/A |
INTRINSIC |
|
low complexity region
|
331 |
343 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
380 |
637 |
5.9e-10 |
PFAM |
|
SCOP:d1lci__
|
675 |
875 |
2e-8 |
SMART |
|
Pfam:AMP-binding
|
947 |
1421 |
1.2e-56 |
PFAM |
|
low complexity region
|
1484 |
1496 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000174552
AA Change: K1120E
PolyPhen 2
Score 0.831 (Sensitivity: 0.84; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000133806
Gene: ENSMUSG00000048264
AA Change: K1120E
| Domain | Start | End | E-Value | Type |
|---|
|
DMAP_binding
|
7 |
120 |
3.55e-43 |
SMART |
|
low complexity region
|
170 |
187 |
N/A |
INTRINSIC |
|
low complexity region
|
275 |
287 |
N/A |
INTRINSIC |
|
Pfam:AMP-binding
|
324 |
800 |
2.7e-20 |
PFAM |
|
Pfam:AMP-binding
|
976 |
1450 |
1.3e-56 |
PFAM |
|
low complexity region
|
1513 |
1525 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000222280
AA Change: K223E
PolyPhen 2
Score 0.885 (Sensitivity: 0.82; Specificity: 0.94)
|
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.0%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the disco-interacting protein homolog 2 family. The protein shares strong similarity with a Drosophila protein which interacts with the transcription factor disco and is expressed in the nervous system. [provided by RefSeq, Oct 2008]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 84 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcf1 |
A |
T |
17: 36,270,342 (GRCm39) |
V616E |
possibly damaging |
Het |
| Adam21 |
A |
G |
12: 81,605,692 (GRCm39) |
V690A |
probably benign |
Het |
| Afg3l1 |
A |
T |
8: 124,228,119 (GRCm39) |
T635S |
probably damaging |
Het |
| Ahcyl2 |
T |
A |
6: 29,890,700 (GRCm39) |
M390K |
probably benign |
Het |
| Ank3 |
T |
A |
10: 69,734,053 (GRCm39) |
|
probably null |
Het |
| Antkmt |
T |
G |
17: 26,010,652 (GRCm39) |
|
probably null |
Het |
| Arhgef3 |
A |
T |
14: 27,106,170 (GRCm39) |
K151N |
probably damaging |
Het |
| Ccr3 |
T |
G |
9: 123,829,043 (GRCm39) |
F126C |
probably damaging |
Het |
| Ccser1 |
A |
G |
6: 61,695,175 (GRCm39) |
D170G |
possibly damaging |
Het |
| Celsr2 |
T |
A |
3: 108,310,074 (GRCm39) |
D1552V |
probably damaging |
Het |
| Cfap69 |
G |
A |
5: 5,675,820 (GRCm39) |
L265F |
probably damaging |
Het |
| Chrna9 |
C |
T |
5: 66,126,533 (GRCm39) |
R92* |
probably null |
Het |
| Cog3 |
A |
T |
14: 75,970,394 (GRCm39) |
V341D |
probably damaging |
Het |
| Csmd1 |
C |
A |
8: 16,073,779 (GRCm39) |
R2072L |
probably damaging |
Het |
| Dbf4 |
G |
T |
5: 8,448,039 (GRCm39) |
H390Q |
probably benign |
Het |
| Dcaf4 |
T |
A |
12: 83,579,078 (GRCm39) |
C166S |
possibly damaging |
Het |
| Dclk3 |
T |
A |
9: 111,297,110 (GRCm39) |
L218Q |
possibly damaging |
Het |
| Dip2b |
T |
A |
15: 100,069,603 (GRCm39) |
W643R |
probably damaging |
Het |
| Dis3 |
T |
A |
14: 99,326,340 (GRCm39) |
H415L |
probably damaging |
Het |
| Dnah7a |
T |
A |
1: 53,542,737 (GRCm39) |
I2478F |
possibly damaging |
Het |
| Dnah8 |
G |
A |
17: 30,967,542 (GRCm39) |
D2585N |
probably benign |
Het |
| Doc2a |
T |
C |
7: 126,447,752 (GRCm39) |
|
probably benign |
Het |
| Dph5 |
A |
T |
3: 115,693,456 (GRCm39) |
M125L |
probably benign |
Het |
| Dst |
A |
T |
1: 34,267,764 (GRCm39) |
T5247S |
possibly damaging |
Het |
| Eno4 |
T |
G |
19: 58,952,889 (GRCm39) |
V477G |
possibly damaging |
Het |
| Exosc8 |
T |
C |
3: 54,636,711 (GRCm39) |
I207V |
possibly damaging |
Het |
| Fat4 |
T |
A |
3: 39,061,352 (GRCm39) |
S4312T |
probably benign |
Het |
| Fgfr2 |
T |
C |
7: 129,843,007 (GRCm39) |
D126G |
probably damaging |
Het |
| Fgfr4 |
A |
G |
13: 55,315,983 (GRCm39) |
T799A |
unknown |
Het |
| Gcn1 |
A |
T |
5: 115,730,203 (GRCm39) |
D839V |
probably benign |
Het |
| Gprin3 |
A |
G |
6: 59,331,158 (GRCm39) |
V383A |
probably benign |
Het |
| Gpt |
T |
C |
15: 76,583,040 (GRCm39) |
V361A |
probably benign |
Het |
| Hepacam |
G |
A |
9: 37,293,060 (GRCm39) |
C217Y |
probably damaging |
Het |
| Hsp90aa1 |
A |
T |
12: 110,660,151 (GRCm39) |
Y382N |
probably damaging |
Het |
| Htr2a |
T |
A |
14: 74,879,462 (GRCm39) |
N30K |
probably benign |
Het |
| Jhy |
A |
T |
9: 40,872,299 (GRCm39) |
M70K |
possibly damaging |
Het |
| Lrrc19 |
T |
C |
4: 94,529,174 (GRCm39) |
Y36C |
probably damaging |
Het |
| Madcam1 |
C |
T |
10: 79,501,447 (GRCm39) |
Q171* |
probably null |
Het |
| Mcm8 |
G |
A |
2: 132,680,629 (GRCm39) |
M544I |
probably benign |
Het |
| Mdga1 |
C |
T |
17: 30,076,580 (GRCm39) |
G64E |
probably damaging |
Het |
| Mmp3 |
A |
G |
9: 7,446,994 (GRCm39) |
D58G |
probably benign |
Het |
| Ms4a10 |
T |
C |
19: 10,942,132 (GRCm39) |
Y123C |
probably damaging |
Het |
| Ms4a4d |
T |
A |
19: 11,535,296 (GRCm39) |
I198K |
probably benign |
Het |
| Mthfd1l |
A |
T |
10: 3,930,241 (GRCm39) |
D112V |
probably benign |
Het |
| N4bp2l2 |
A |
C |
5: 150,566,606 (GRCm39) |
S567R |
probably benign |
Het |
| Ndufaf2 |
A |
G |
13: 108,295,010 (GRCm39) |
Y32H |
probably damaging |
Het |
| Nup153 |
T |
A |
13: 46,866,213 (GRCm39) |
K182* |
probably null |
Het |
| Or4c100 |
A |
G |
2: 88,356,079 (GRCm39) |
T51A |
probably benign |
Het |
| Or52p2 |
A |
G |
7: 102,237,623 (GRCm39) |
F109S |
probably damaging |
Het |
| Or5p4 |
T |
A |
7: 107,680,781 (GRCm39) |
V260E |
probably damaging |
Het |
| Otoa |
T |
C |
7: 120,754,358 (GRCm39) |
S928P |
probably damaging |
Het |
| Oxct2a |
T |
C |
4: 123,216,496 (GRCm39) |
D295G |
probably benign |
Het |
| P4ha2 |
C |
A |
11: 54,015,846 (GRCm39) |
T411K |
probably benign |
Het |
| Plcg2 |
A |
T |
8: 118,333,822 (GRCm39) |
Q865L |
probably benign |
Het |
| Prepl |
G |
T |
17: 85,385,932 (GRCm39) |
T244K |
possibly damaging |
Het |
| Ptpro |
A |
T |
6: 137,388,103 (GRCm39) |
K776* |
probably null |
Het |
| Rc3h2 |
T |
C |
2: 37,279,844 (GRCm39) |
K462E |
possibly damaging |
Het |
| Scn10a |
A |
G |
9: 119,516,940 (GRCm39) |
|
probably null |
Het |
| Serpinb1c |
A |
G |
13: 33,066,147 (GRCm39) |
V266A |
probably damaging |
Het |
| Slc6a20b |
T |
A |
9: 123,433,861 (GRCm39) |
N326Y |
probably damaging |
Het |
| Spcs2 |
C |
T |
7: 99,508,038 (GRCm39) |
G16D |
possibly damaging |
Het |
| Spns3 |
T |
C |
11: 72,390,321 (GRCm39) |
D441G |
possibly damaging |
Het |
| Srsf4 |
A |
G |
4: 131,618,556 (GRCm39) |
D49G |
probably damaging |
Het |
| Tec |
A |
T |
5: 72,917,736 (GRCm39) |
C494* |
probably null |
Het |
| Tecpr1 |
A |
T |
5: 144,141,476 (GRCm39) |
Y798N |
probably damaging |
Het |
| Tex56 |
A |
T |
13: 35,116,613 (GRCm39) |
T121S |
possibly damaging |
Het |
| Tmt1a |
T |
A |
15: 100,202,987 (GRCm39) |
F87Y |
probably benign |
Het |
| Trim56 |
C |
T |
5: 137,143,343 (GRCm39) |
E58K |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,626,478 (GRCm39) |
D13146E |
probably damaging |
Het |
| Ube2q1 |
A |
T |
3: 89,686,790 (GRCm39) |
K46* |
probably null |
Het |
| Ucn |
G |
T |
5: 31,295,842 (GRCm39) |
T8K |
probably benign |
Het |
| Usp25 |
T |
C |
16: 76,830,870 (GRCm39) |
|
probably null |
Het |
| Usp48 |
A |
T |
4: 137,343,144 (GRCm39) |
Q430L |
probably benign |
Het |
| Usp48 |
A |
T |
4: 137,343,145 (GRCm39) |
|
probably null |
Het |
| Vill |
A |
T |
9: 118,890,579 (GRCm39) |
D164V |
probably damaging |
Het |
| Vmn2r91 |
T |
A |
17: 18,356,751 (GRCm39) |
M806K |
possibly damaging |
Het |
| Wdfy4 |
T |
A |
14: 32,750,970 (GRCm39) |
Y2256F |
probably damaging |
Het |
| Wsb1 |
A |
G |
11: 79,141,826 (GRCm39) |
S64P |
probably damaging |
Het |
| Zc3h11a |
C |
A |
1: 133,552,350 (GRCm39) |
V586F |
probably benign |
Het |
| Zc3h12d |
A |
G |
10: 7,729,014 (GRCm39) |
D126G |
probably damaging |
Het |
| Zfp296 |
G |
T |
7: 19,313,637 (GRCm39) |
C164F |
possibly damaging |
Het |
| Zfp442 |
T |
A |
2: 150,251,635 (GRCm39) |
H89L |
possibly damaging |
Het |
| Zfp82 |
T |
A |
7: 29,756,312 (GRCm39) |
|
probably null |
Het |
| Zmynd8 |
A |
G |
2: 165,676,871 (GRCm39) |
V249A |
possibly damaging |
Het |
|
| Other mutations in Dip2c |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00392:Dip2c
|
APN |
13 |
9,543,144 (GRCm39) |
missense |
probably damaging |
0.97 |
|
IGL00426:Dip2c
|
APN |
13 |
9,656,551 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00503:Dip2c
|
APN |
13 |
9,617,934 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00586:Dip2c
|
APN |
13 |
9,660,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01306:Dip2c
|
APN |
13 |
9,625,179 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
IGL01580:Dip2c
|
APN |
13 |
9,687,124 (GRCm39) |
splice site |
probably null |
|
|
IGL01985:Dip2c
|
APN |
13 |
9,603,303 (GRCm39) |
splice site |
probably benign |
|
|
IGL02060:Dip2c
|
APN |
13 |
9,672,666 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02122:Dip2c
|
APN |
13 |
9,556,695 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL02170:Dip2c
|
APN |
13 |
9,656,371 (GRCm39) |
missense |
probably benign |
0.03 |
|
IGL02211:Dip2c
|
APN |
13 |
9,660,883 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02755:Dip2c
|
APN |
13 |
9,600,356 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL02836:Dip2c
|
APN |
13 |
9,660,826 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02935:Dip2c
|
APN |
13 |
9,712,182 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03032:Dip2c
|
APN |
13 |
9,601,814 (GRCm39) |
missense |
probably damaging |
1.00 |
|
ANU23:Dip2c
|
UTSW |
13 |
9,625,179 (GRCm39) |
missense |
possibly damaging |
0.72 |
|
P0038:Dip2c
|
UTSW |
13 |
9,697,018 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0009:Dip2c
|
UTSW |
13 |
9,671,939 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0268:Dip2c
|
UTSW |
13 |
9,687,186 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0271:Dip2c
|
UTSW |
13 |
9,665,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0306:Dip2c
|
UTSW |
13 |
9,654,635 (GRCm39) |
missense |
probably benign |
0.09 |
|
R0415:Dip2c
|
UTSW |
13 |
9,618,325 (GRCm39) |
splice site |
probably benign |
|
|
R0519:Dip2c
|
UTSW |
13 |
9,613,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0557:Dip2c
|
UTSW |
13 |
9,603,495 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0964:Dip2c
|
UTSW |
13 |
9,618,699 (GRCm39) |
missense |
probably benign |
0.43 |
|
R0973:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0973:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0974:Dip2c
|
UTSW |
13 |
9,626,944 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1101:Dip2c
|
UTSW |
13 |
9,684,780 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1171:Dip2c
|
UTSW |
13 |
9,543,162 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1403:Dip2c
|
UTSW |
13 |
9,603,300 (GRCm39) |
splice site |
probably null |
|
|
R1403:Dip2c
|
UTSW |
13 |
9,603,300 (GRCm39) |
splice site |
probably null |
|
|
R1432:Dip2c
|
UTSW |
13 |
9,603,340 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1481:Dip2c
|
UTSW |
13 |
9,601,902 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1588:Dip2c
|
UTSW |
13 |
9,715,900 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1721:Dip2c
|
UTSW |
13 |
9,709,404 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1726:Dip2c
|
UTSW |
13 |
9,625,464 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1867:Dip2c
|
UTSW |
13 |
9,671,985 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R1909:Dip2c
|
UTSW |
13 |
9,583,386 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2013:Dip2c
|
UTSW |
13 |
9,617,882 (GRCm39) |
nonsense |
probably null |
|
|
R2022:Dip2c
|
UTSW |
13 |
9,601,836 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2517:Dip2c
|
UTSW |
13 |
9,659,041 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3746:Dip2c
|
UTSW |
13 |
9,651,509 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3794:Dip2c
|
UTSW |
13 |
9,654,597 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3884:Dip2c
|
UTSW |
13 |
9,601,894 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4019:Dip2c
|
UTSW |
13 |
9,664,401 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4110:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4111:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4113:Dip2c
|
UTSW |
13 |
9,687,137 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4256:Dip2c
|
UTSW |
13 |
9,659,092 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4300:Dip2c
|
UTSW |
13 |
9,660,747 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4494:Dip2c
|
UTSW |
13 |
9,621,098 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4739:Dip2c
|
UTSW |
13 |
9,583,375 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4812:Dip2c
|
UTSW |
13 |
9,687,166 (GRCm39) |
nonsense |
probably null |
|
|
R4814:Dip2c
|
UTSW |
13 |
9,586,896 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4816:Dip2c
|
UTSW |
13 |
9,625,186 (GRCm39) |
missense |
probably benign |
0.37 |
|
R4828:Dip2c
|
UTSW |
13 |
9,610,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4915:Dip2c
|
UTSW |
13 |
9,671,905 (GRCm39) |
splice site |
probably null |
|
|
R4917:Dip2c
|
UTSW |
13 |
9,671,905 (GRCm39) |
splice site |
probably null |
|
|
R4993:Dip2c
|
UTSW |
13 |
9,625,259 (GRCm39) |
nonsense |
probably null |
|
|
R5043:Dip2c
|
UTSW |
13 |
9,601,863 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R5349:Dip2c
|
UTSW |
13 |
9,672,689 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5744:Dip2c
|
UTSW |
13 |
9,618,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5840:Dip2c
|
UTSW |
13 |
9,556,712 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R6110:Dip2c
|
UTSW |
13 |
9,673,802 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6160:Dip2c
|
UTSW |
13 |
9,583,290 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6161:Dip2c
|
UTSW |
13 |
9,697,043 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6477:Dip2c
|
UTSW |
13 |
9,673,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6522:Dip2c
|
UTSW |
13 |
9,625,264 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6603:Dip2c
|
UTSW |
13 |
9,704,624 (GRCm39) |
splice site |
probably null |
|
|
R6658:Dip2c
|
UTSW |
13 |
9,543,213 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6672:Dip2c
|
UTSW |
13 |
9,617,866 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6697:Dip2c
|
UTSW |
13 |
9,671,949 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,684,868 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6991:Dip2c
|
UTSW |
13 |
9,601,896 (GRCm39) |
nonsense |
probably null |
|
|
R7018:Dip2c
|
UTSW |
13 |
9,709,314 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7053:Dip2c
|
UTSW |
13 |
9,660,740 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7102:Dip2c
|
UTSW |
13 |
9,654,572 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7171:Dip2c
|
UTSW |
13 |
9,556,684 (GRCm39) |
missense |
probably benign |
0.34 |
|
R7371:Dip2c
|
UTSW |
13 |
9,642,785 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7395:Dip2c
|
UTSW |
13 |
9,664,413 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7489:Dip2c
|
UTSW |
13 |
9,583,348 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7575:Dip2c
|
UTSW |
13 |
9,678,048 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R7642:Dip2c
|
UTSW |
13 |
9,672,741 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7687:Dip2c
|
UTSW |
13 |
9,654,617 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7699:Dip2c
|
UTSW |
13 |
9,709,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7700:Dip2c
|
UTSW |
13 |
9,709,347 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7715:Dip2c
|
UTSW |
13 |
9,664,427 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7842:Dip2c
|
UTSW |
13 |
9,656,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7845:Dip2c
|
UTSW |
13 |
9,659,080 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8354:Dip2c
|
UTSW |
13 |
9,671,918 (GRCm39) |
missense |
probably benign |
0.05 |
|
R8685:Dip2c
|
UTSW |
13 |
9,687,161 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8779:Dip2c
|
UTSW |
13 |
9,660,845 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8786:Dip2c
|
UTSW |
13 |
9,665,830 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8815:Dip2c
|
UTSW |
13 |
9,673,834 (GRCm39) |
nonsense |
probably null |
|
|
R8833:Dip2c
|
UTSW |
13 |
9,625,519 (GRCm39) |
critical splice donor site |
probably null |
|
|
R8868:Dip2c
|
UTSW |
13 |
9,625,503 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R8873:Dip2c
|
UTSW |
13 |
9,625,182 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8887:Dip2c
|
UTSW |
13 |
9,673,989 (GRCm39) |
splice site |
probably benign |
|
|
R8923:Dip2c
|
UTSW |
13 |
9,673,901 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9112:Dip2c
|
UTSW |
13 |
9,660,766 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9424:Dip2c
|
UTSW |
13 |
9,709,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9474:Dip2c
|
UTSW |
13 |
9,544,963 (GRCm39) |
missense |
unknown |
|
|
R9527:Dip2c
|
UTSW |
13 |
9,544,875 (GRCm39) |
missense |
unknown |
|
|
R9593:Dip2c
|
UTSW |
13 |
9,704,683 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R9615:Dip2c
|
UTSW |
13 |
9,625,191 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9801:Dip2c
|
UTSW |
13 |
9,626,936 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGTCGATCTGCTTGTCTCATG -3'
(R):5'- TCTCCATGCATCACTGGAATAC -3'
Sequencing Primer
(F):5'- CTGATATGTAAACTGCTTCGGTCCAG -3'
(R):5'- ATGCATCACTGGAATACAATCAC -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation