Incidental Mutation 'R4928:Dnajc13'
| ID |
381017 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dnajc13
|
| Ensembl Gene |
ENSMUSG00000032560 |
| Gene Name |
DnaJ heat shock protein family (Hsp40) member C13 |
| Synonyms |
Rme8, D030002L11Rik, LOC382100 |
| MMRRC Submission |
042529-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably essential
(E-score: 0.940)
|
| Stock # |
R4928 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
9 |
| Chromosomal Location |
104028481-104140129 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 104110837 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Aspartic acid
at position 145
(N145D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000035170
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000035170]
[ENSMUST00000186788]
|
| AlphaFold |
D4AFX7 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000035170
AA Change: N145D
PolyPhen 2
Score 0.925 (Sensitivity: 0.81; Specificity: 0.94)
|
| SMART Domains |
Protein: ENSMUSP00000035170
Gene: ENSMUSG00000032560
AA Change: N145D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
706 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
832 |
843 |
N/A |
INTRINSIC |
|
low complexity region
|
913 |
926 |
N/A |
INTRINSIC |
|
Blast:ARM
|
927 |
963 |
6e-12 |
BLAST |
|
Pfam:DUF4339
|
976 |
1020 |
1.5e-18 |
PFAM |
|
Blast:ARM
|
1071 |
1110 |
5e-12 |
BLAST |
|
DnaJ
|
1300 |
1358 |
5.69e-18 |
SMART |
|
low complexity region
|
1417 |
1426 |
N/A |
INTRINSIC |
|
low complexity region
|
1813 |
1829 |
N/A |
INTRINSIC |
|
Blast:ARM
|
1843 |
1884 |
6e-8 |
BLAST |
|
low complexity region
|
1968 |
1984 |
N/A |
INTRINSIC |
|
low complexity region
|
2006 |
2016 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000186788
AA Change: N145D
PolyPhen 2
Score 0.644 (Sensitivity: 0.87; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000139804
Gene: ENSMUSG00000032560
AA Change: N145D
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
706 |
719 |
N/A |
INTRINSIC |
|
low complexity region
|
837 |
848 |
N/A |
INTRINSIC |
|
low complexity region
|
918 |
931 |
N/A |
INTRINSIC |
|
Blast:ARM
|
932 |
968 |
6e-12 |
BLAST |
|
Pfam:DUF4339
|
980 |
1025 |
8.1e-14 |
PFAM |
|
Blast:ARM
|
1076 |
1115 |
5e-12 |
BLAST |
|
DnaJ
|
1305 |
1363 |
5.69e-18 |
SMART |
|
low complexity region
|
1422 |
1431 |
N/A |
INTRINSIC |
|
low complexity region
|
1818 |
1834 |
N/A |
INTRINSIC |
|
Blast:ARM
|
1848 |
1889 |
6e-8 |
BLAST |
|
low complexity region
|
1973 |
1989 |
N/A |
INTRINSIC |
|
low complexity region
|
2011 |
2021 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000189299
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000190600
|
| Meta Mutation Damage Score |
0.1234 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.3%
- 20x: 92.5%
|
| Validation Efficiency |
98% (123/126) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the Dnaj protein family whose members act as co-chaperones of a partner heat-shock protein by binding to the latter and stimulating ATP hydrolysis. The encoded protein associates with the heat-shock protein Hsc70 and plays a role in clathrin-mediated endocytosis. It may also be involved in post-endocytic transport mechanisms via its associations with other proteins, including the sorting nexin SNX1. Mutations in this gene are associated with Parkinson's disease. [provided by RefSeq, Jun 2016]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 110 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A530021J07Rik |
G |
T |
7: 82,805,086 (GRCm39) |
|
noncoding transcript |
Het |
| Aasdh |
T |
A |
5: 77,044,535 (GRCm39) |
K118N |
possibly damaging |
Het |
| Abca14 |
A |
T |
7: 119,923,803 (GRCm39) |
N1620I |
possibly damaging |
Het |
| Acap1 |
A |
T |
11: 69,776,641 (GRCm39) |
S149T |
possibly damaging |
Het |
| Adgre1 |
T |
A |
17: 57,751,064 (GRCm39) |
Y579* |
probably null |
Het |
| Aifm3 |
T |
C |
16: 17,318,296 (GRCm39) |
|
probably benign |
Het |
| Aldh16a1 |
A |
G |
7: 44,791,385 (GRCm39) |
W107R |
probably damaging |
Het |
| Amer2 |
A |
T |
14: 60,616,894 (GRCm39) |
H363L |
possibly damaging |
Het |
| Arhgap10 |
A |
G |
8: 78,152,957 (GRCm39) |
|
probably null |
Het |
| Arhgef6 |
A |
T |
X: 56,280,238 (GRCm39) |
D742E |
probably damaging |
Het |
| Astn2 |
A |
T |
4: 65,647,644 (GRCm39) |
N731K |
probably damaging |
Het |
| Atp1a2 |
T |
C |
1: 172,105,954 (GRCm39) |
T904A |
possibly damaging |
Het |
| Atr |
C |
T |
9: 95,789,352 (GRCm39) |
R1503W |
probably damaging |
Het |
| Cdh3 |
G |
T |
8: 107,263,242 (GRCm39) |
R97L |
probably benign |
Het |
| Chst2 |
C |
T |
9: 95,288,059 (GRCm39) |
V96I |
probably benign |
Het |
| Cit |
T |
A |
5: 116,123,856 (GRCm39) |
N1464K |
probably benign |
Het |
| Col17a1 |
A |
T |
19: 47,658,897 (GRCm39) |
|
probably null |
Het |
| Col4a3 |
G |
A |
1: 82,688,698 (GRCm39) |
|
probably benign |
Het |
| Copz1 |
T |
A |
15: 103,199,757 (GRCm39) |
S57R |
probably damaging |
Het |
| Cpped1 |
A |
T |
16: 11,646,143 (GRCm39) |
F227Y |
probably damaging |
Het |
| Cyp2j12 |
A |
T |
4: 95,990,388 (GRCm39) |
|
probably null |
Het |
| Dctn1 |
T |
A |
6: 83,166,189 (GRCm39) |
I195N |
possibly damaging |
Het |
| Dhrs7b |
A |
G |
11: 60,742,751 (GRCm39) |
I148V |
probably benign |
Het |
| Dnah17 |
T |
C |
11: 117,918,259 (GRCm39) |
D4096G |
probably damaging |
Het |
| Ecpas |
A |
G |
4: 58,827,073 (GRCm39) |
V1020A |
probably damaging |
Het |
| Entrep2 |
G |
T |
7: 64,409,116 (GRCm39) |
S426* |
probably null |
Het |
| Ercc6l2 |
T |
C |
13: 64,042,627 (GRCm39) |
|
probably benign |
Het |
| Fads6 |
T |
G |
11: 115,187,387 (GRCm39) |
I103L |
probably benign |
Het |
| Fat4 |
T |
G |
3: 39,064,614 (GRCm39) |
Y4857D |
probably damaging |
Het |
| Fbxl14 |
T |
A |
6: 119,457,671 (GRCm39) |
L284Q |
probably damaging |
Het |
| Fkbp9 |
T |
C |
6: 56,826,655 (GRCm39) |
V85A |
possibly damaging |
Het |
| Galnt13 |
T |
A |
2: 54,406,577 (GRCm39) |
V9E |
probably damaging |
Het |
| Gm14412 |
A |
T |
2: 177,006,373 (GRCm39) |
S507R |
probably benign |
Het |
| Gm15142 |
T |
A |
X: 153,421,415 (GRCm39) |
|
noncoding transcript |
Het |
| Gm4787 |
T |
C |
12: 81,425,612 (GRCm39) |
E182G |
probably benign |
Het |
| Gm6811 |
C |
A |
17: 21,314,893 (GRCm39) |
|
noncoding transcript |
Het |
| Gm9791 |
A |
T |
3: 34,059,218 (GRCm39) |
|
noncoding transcript |
Het |
| Hoxb7 |
A |
T |
11: 96,180,336 (GRCm39) |
|
probably null |
Het |
| Ift122 |
T |
A |
6: 115,892,819 (GRCm39) |
|
probably benign |
Het |
| Krt28 |
C |
T |
11: 99,265,458 (GRCm39) |
V70I |
probably benign |
Het |
| Lig1 |
T |
C |
7: 13,032,664 (GRCm39) |
S459P |
probably damaging |
Het |
| Lrfn3 |
C |
T |
7: 30,060,048 (GRCm39) |
R59H |
possibly damaging |
Het |
| Mavs |
T |
C |
2: 131,088,663 (GRCm39) |
V489A |
probably benign |
Het |
| Mcm8 |
C |
T |
2: 132,681,399 (GRCm39) |
P625L |
probably benign |
Het |
| Megf10 |
G |
T |
18: 57,373,745 (GRCm39) |
R181L |
probably benign |
Het |
| Mgrn1 |
G |
A |
16: 4,745,726 (GRCm39) |
G440D |
probably benign |
Het |
| Mllt3 |
T |
C |
4: 87,700,642 (GRCm39) |
|
probably null |
Het |
| Muc5ac |
T |
A |
7: 141,371,639 (GRCm39) |
Y2613* |
probably null |
Het |
| Myh14 |
C |
T |
7: 44,284,926 (GRCm39) |
G662S |
probably benign |
Het |
| Myod1 |
T |
A |
7: 46,026,474 (GRCm39) |
N126K |
probably damaging |
Het |
| Nae1 |
A |
T |
8: 105,242,774 (GRCm39) |
H439Q |
possibly damaging |
Het |
| Narf |
T |
A |
11: 121,135,765 (GRCm39) |
V136E |
possibly damaging |
Het |
| Ncapd3 |
T |
A |
9: 26,983,031 (GRCm39) |
C926* |
probably null |
Het |
| Ndufv2 |
C |
A |
17: 66,399,653 (GRCm39) |
|
probably null |
Het |
| Neb |
T |
C |
2: 52,102,987 (GRCm39) |
S449G |
possibly damaging |
Het |
| Nek10 |
C |
T |
14: 14,930,577 (GRCm38) |
P698L |
probably damaging |
Het |
| Nox3 |
T |
A |
17: 3,685,550 (GRCm39) |
E566V |
probably null |
Het |
| Oas1a |
C |
T |
5: 121,043,787 (GRCm39) |
R115H |
probably benign |
Het |
| Or10ag60 |
C |
A |
2: 87,438,487 (GRCm39) |
L252I |
probably benign |
Het |
| Or51b6 |
A |
G |
7: 103,555,879 (GRCm39) |
T78A |
probably damaging |
Het |
| Or5w19 |
A |
G |
2: 87,698,574 (GRCm39) |
M80V |
probably benign |
Het |
| Or8k30 |
T |
A |
2: 86,339,469 (GRCm39) |
L222H |
probably damaging |
Het |
| Pbld2 |
A |
G |
10: 62,883,778 (GRCm39) |
H142R |
probably damaging |
Het |
| Pcdha4 |
C |
T |
18: 37,087,869 (GRCm39) |
T684M |
probably benign |
Het |
| Phc3 |
G |
T |
3: 31,005,068 (GRCm39) |
T175N |
probably damaging |
Het |
| Pigs |
G |
T |
11: 78,219,828 (GRCm39) |
V68L |
probably damaging |
Het |
| Pik3c2g |
T |
A |
6: 139,913,528 (GRCm39) |
D857E |
possibly damaging |
Het |
| Pitpnm3 |
G |
A |
11: 71,953,998 (GRCm39) |
P550S |
probably damaging |
Het |
| Pla2g15 |
G |
A |
8: 106,889,850 (GRCm39) |
W374* |
probably null |
Het |
| Ptpn14 |
G |
A |
1: 189,554,839 (GRCm39) |
C133Y |
probably damaging |
Het |
| Ptpn20 |
A |
G |
14: 33,336,446 (GRCm39) |
N95S |
probably benign |
Het |
| Ptrh2 |
G |
T |
11: 86,580,862 (GRCm39) |
V160F |
probably damaging |
Het |
| Rapgef3 |
T |
C |
15: 97,655,256 (GRCm39) |
D486G |
probably damaging |
Het |
| Rev3l |
T |
G |
10: 39,699,981 (GRCm39) |
S1493A |
probably benign |
Het |
| Rgs9 |
T |
A |
11: 109,116,570 (GRCm39) |
D411V |
probably benign |
Het |
| Rgsl1 |
A |
T |
1: 153,669,514 (GRCm39) |
Y291N |
probably damaging |
Het |
| Rprd2 |
A |
G |
3: 95,671,849 (GRCm39) |
Y1185H |
probably damaging |
Het |
| Rpusd3 |
A |
G |
6: 113,393,167 (GRCm39) |
|
probably benign |
Het |
| Scnn1a |
T |
C |
6: 125,299,136 (GRCm39) |
I72T |
probably damaging |
Het |
| Sdk1 |
A |
T |
5: 141,842,758 (GRCm39) |
|
probably benign |
Het |
| Sfmbt2 |
T |
C |
2: 10,450,556 (GRCm39) |
L277P |
probably benign |
Het |
| Sgf29 |
A |
G |
7: 126,264,154 (GRCm39) |
E73G |
probably damaging |
Het |
| Slc12a6 |
T |
A |
2: 112,183,306 (GRCm39) |
F764L |
probably damaging |
Het |
| Slc4a2 |
T |
C |
5: 24,640,340 (GRCm39) |
|
probably null |
Het |
| Slc9a3 |
T |
G |
13: 74,305,838 (GRCm39) |
V285G |
probably damaging |
Het |
| Slc9c1 |
A |
G |
16: 45,395,772 (GRCm39) |
T608A |
probably benign |
Het |
| Slfnl1 |
C |
T |
4: 120,392,882 (GRCm39) |
R325C |
probably damaging |
Het |
| Smarcad1 |
T |
A |
6: 65,051,898 (GRCm39) |
F344I |
probably benign |
Het |
| Snrnp70 |
A |
T |
7: 45,026,705 (GRCm39) |
|
probably null |
Het |
| Sod2 |
C |
T |
17: 13,227,073 (GRCm39) |
T9M |
probably benign |
Het |
| Spag5 |
T |
A |
11: 78,205,199 (GRCm39) |
S633T |
probably damaging |
Het |
| Spta1 |
A |
T |
1: 174,018,622 (GRCm39) |
I531L |
probably benign |
Het |
| Stra8 |
A |
G |
6: 34,910,091 (GRCm39) |
E60G |
probably benign |
Het |
| Sult2a3 |
T |
A |
7: 13,845,482 (GRCm39) |
I126F |
probably benign |
Het |
| Syt1 |
T |
C |
10: 108,340,373 (GRCm39) |
H315R |
possibly damaging |
Het |
| Tanc2 |
T |
C |
11: 105,758,588 (GRCm39) |
L783P |
probably damaging |
Het |
| Thbs2 |
C |
T |
17: 14,899,162 (GRCm39) |
C646Y |
probably damaging |
Het |
| Ticam2 |
T |
A |
18: 46,693,989 (GRCm39) |
K33* |
probably null |
Het |
| Trim17 |
T |
C |
11: 58,845,127 (GRCm39) |
|
probably benign |
Het |
| Tsr1 |
G |
A |
11: 74,798,705 (GRCm39) |
M691I |
probably benign |
Het |
| Ttn |
T |
A |
2: 76,592,763 (GRCm39) |
I20790F |
probably damaging |
Het |
| Tubb2b |
A |
T |
13: 34,312,168 (GRCm39) |
Y208* |
probably null |
Het |
| Ubr1 |
T |
A |
2: 120,745,419 (GRCm39) |
I890F |
probably damaging |
Het |
| Usp54 |
T |
C |
14: 20,612,260 (GRCm39) |
E852G |
probably damaging |
Het |
| Vmn2r78 |
T |
C |
7: 86,603,835 (GRCm39) |
V671A |
probably damaging |
Het |
| Wipi1 |
T |
C |
11: 109,470,475 (GRCm39) |
K315E |
probably benign |
Het |
| Xrn2 |
T |
C |
2: 146,893,638 (GRCm39) |
V735A |
possibly damaging |
Het |
| Zdbf2 |
T |
A |
1: 63,347,973 (GRCm39) |
D2117E |
possibly damaging |
Het |
| Zfp287 |
A |
T |
11: 62,604,962 (GRCm39) |
C648* |
probably null |
Het |
| Zfp369 |
A |
G |
13: 65,444,614 (GRCm39) |
T586A |
possibly damaging |
Het |
|
| Other mutations in Dnajc13 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00743:Dnajc13
|
APN |
9 |
104,039,979 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL00754:Dnajc13
|
APN |
9 |
104,051,697 (GRCm39) |
nonsense |
probably null |
|
|
IGL00914:Dnajc13
|
APN |
9 |
104,090,081 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL01014:Dnajc13
|
APN |
9 |
104,080,417 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01077:Dnajc13
|
APN |
9 |
104,108,220 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL01137:Dnajc13
|
APN |
9 |
104,037,689 (GRCm39) |
missense |
probably benign |
|
|
IGL01305:Dnajc13
|
APN |
9 |
104,107,836 (GRCm39) |
splice site |
probably null |
|
|
IGL01707:Dnajc13
|
APN |
9 |
104,106,178 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01781:Dnajc13
|
APN |
9 |
104,039,558 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL01868:Dnajc13
|
APN |
9 |
104,039,944 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
IGL01950:Dnajc13
|
APN |
9 |
104,067,631 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
IGL02102:Dnajc13
|
APN |
9 |
104,106,208 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
IGL02350:Dnajc13
|
APN |
9 |
104,039,558 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02357:Dnajc13
|
APN |
9 |
104,039,558 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02470:Dnajc13
|
APN |
9 |
104,052,946 (GRCm39) |
missense |
probably benign |
0.17 |
|
IGL02888:Dnajc13
|
APN |
9 |
104,057,261 (GRCm39) |
splice site |
probably benign |
|
|
IGL03079:Dnajc13
|
APN |
9 |
104,090,068 (GRCm39) |
nonsense |
probably null |
|
|
IGL03179:Dnajc13
|
APN |
9 |
104,044,634 (GRCm39) |
missense |
probably benign |
0.42 |
|
IGL03293:Dnajc13
|
APN |
9 |
104,051,625 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
impressario
|
UTSW |
9 |
104,091,085 (GRCm39) |
missense |
probably benign |
0.12 |
|
Kaiser
|
UTSW |
9 |
104,091,387 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB008:Dnajc13
|
UTSW |
9 |
104,095,763 (GRCm39) |
missense |
probably benign |
0.02 |
|
BB018:Dnajc13
|
UTSW |
9 |
104,095,763 (GRCm39) |
missense |
probably benign |
0.02 |
|
PIT4142001:Dnajc13
|
UTSW |
9 |
104,115,672 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R0323:Dnajc13
|
UTSW |
9 |
104,034,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0361:Dnajc13
|
UTSW |
9 |
104,044,258 (GRCm39) |
missense |
probably benign |
0.18 |
|
R0480:Dnajc13
|
UTSW |
9 |
104,077,708 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0558:Dnajc13
|
UTSW |
9 |
104,079,151 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R0707:Dnajc13
|
UTSW |
9 |
104,049,781 (GRCm39) |
missense |
probably benign |
0.12 |
|
R0831:Dnajc13
|
UTSW |
9 |
104,049,811 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1234:Dnajc13
|
UTSW |
9 |
104,091,356 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R1433:Dnajc13
|
UTSW |
9 |
104,057,320 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1463:Dnajc13
|
UTSW |
9 |
104,056,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1464:Dnajc13
|
UTSW |
9 |
104,091,366 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1464:Dnajc13
|
UTSW |
9 |
104,091,366 (GRCm39) |
missense |
probably benign |
0.10 |
|
R1489:Dnajc13
|
UTSW |
9 |
104,108,234 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1575:Dnajc13
|
UTSW |
9 |
104,034,037 (GRCm39) |
missense |
probably benign |
0.29 |
|
R1750:Dnajc13
|
UTSW |
9 |
104,098,676 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1903:Dnajc13
|
UTSW |
9 |
104,106,136 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2066:Dnajc13
|
UTSW |
9 |
104,098,640 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2206:Dnajc13
|
UTSW |
9 |
104,080,717 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3160:Dnajc13
|
UTSW |
9 |
104,097,097 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R3162:Dnajc13
|
UTSW |
9 |
104,097,097 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4158:Dnajc13
|
UTSW |
9 |
104,067,641 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4460:Dnajc13
|
UTSW |
9 |
104,058,262 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R4537:Dnajc13
|
UTSW |
9 |
104,064,004 (GRCm39) |
intron |
probably benign |
|
|
R4538:Dnajc13
|
UTSW |
9 |
104,064,004 (GRCm39) |
intron |
probably benign |
|
|
R4631:Dnajc13
|
UTSW |
9 |
104,067,616 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4662:Dnajc13
|
UTSW |
9 |
104,084,957 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4722:Dnajc13
|
UTSW |
9 |
104,091,017 (GRCm39) |
missense |
probably benign |
|
|
R4731:Dnajc13
|
UTSW |
9 |
104,064,004 (GRCm39) |
intron |
probably benign |
|
|
R4732:Dnajc13
|
UTSW |
9 |
104,064,004 (GRCm39) |
intron |
probably benign |
|
|
R4758:Dnajc13
|
UTSW |
9 |
104,049,773 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4801:Dnajc13
|
UTSW |
9 |
104,052,926 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4802:Dnajc13
|
UTSW |
9 |
104,052,926 (GRCm39) |
missense |
probably benign |
0.16 |
|
R4944:Dnajc13
|
UTSW |
9 |
104,044,586 (GRCm39) |
unclassified |
probably benign |
|
|
R4979:Dnajc13
|
UTSW |
9 |
104,063,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5177:Dnajc13
|
UTSW |
9 |
104,108,185 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5190:Dnajc13
|
UTSW |
9 |
104,051,724 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5256:Dnajc13
|
UTSW |
9 |
104,080,528 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5452:Dnajc13
|
UTSW |
9 |
104,069,313 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5657:Dnajc13
|
UTSW |
9 |
104,105,736 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5752:Dnajc13
|
UTSW |
9 |
104,069,973 (GRCm39) |
splice site |
probably null |
|
|
R5789:Dnajc13
|
UTSW |
9 |
104,091,387 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5837:Dnajc13
|
UTSW |
9 |
104,053,865 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R5846:Dnajc13
|
UTSW |
9 |
104,067,584 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5982:Dnajc13
|
UTSW |
9 |
104,061,814 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R6189:Dnajc13
|
UTSW |
9 |
104,091,085 (GRCm39) |
missense |
probably benign |
0.12 |
|
R6355:Dnajc13
|
UTSW |
9 |
104,080,469 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6483:Dnajc13
|
UTSW |
9 |
104,085,003 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R6613:Dnajc13
|
UTSW |
9 |
104,091,076 (GRCm39) |
missense |
probably benign |
0.07 |
|
R6962:Dnajc13
|
UTSW |
9 |
104,058,208 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7048:Dnajc13
|
UTSW |
9 |
104,080,613 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7101:Dnajc13
|
UTSW |
9 |
104,042,221 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7304:Dnajc13
|
UTSW |
9 |
104,115,713 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7353:Dnajc13
|
UTSW |
9 |
104,107,230 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R7366:Dnajc13
|
UTSW |
9 |
104,061,905 (GRCm39) |
missense |
probably benign |
0.43 |
|
R7528:Dnajc13
|
UTSW |
9 |
104,056,164 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R7635:Dnajc13
|
UTSW |
9 |
104,039,566 (GRCm39) |
missense |
probably benign |
|
|
R7673:Dnajc13
|
UTSW |
9 |
104,110,891 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7856:Dnajc13
|
UTSW |
9 |
104,044,684 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7931:Dnajc13
|
UTSW |
9 |
104,095,763 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7995:Dnajc13
|
UTSW |
9 |
104,051,562 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8319:Dnajc13
|
UTSW |
9 |
104,067,590 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8354:Dnajc13
|
UTSW |
9 |
104,094,927 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8680:Dnajc13
|
UTSW |
9 |
104,057,338 (GRCm39) |
missense |
probably benign |
|
|
R8686:Dnajc13
|
UTSW |
9 |
104,048,004 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8707:Dnajc13
|
UTSW |
9 |
104,069,847 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8847:Dnajc13
|
UTSW |
9 |
104,057,360 (GRCm39) |
nonsense |
probably null |
|
|
R8868:Dnajc13
|
UTSW |
9 |
104,042,987 (GRCm39) |
missense |
probably benign |
0.13 |
|
R8986:Dnajc13
|
UTSW |
9 |
104,057,330 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9139:Dnajc13
|
UTSW |
9 |
104,085,039 (GRCm39) |
missense |
probably benign |
0.02 |
|
R9334:Dnajc13
|
UTSW |
9 |
104,051,659 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9353:Dnajc13
|
UTSW |
9 |
104,067,571 (GRCm39) |
missense |
probably benign |
0.31 |
|
R9470:Dnajc13
|
UTSW |
9 |
104,107,919 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9528:Dnajc13
|
UTSW |
9 |
104,114,904 (GRCm39) |
missense |
probably benign |
|
|
R9578:Dnajc13
|
UTSW |
9 |
104,115,726 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9658:Dnajc13
|
UTSW |
9 |
104,115,728 (GRCm39) |
missense |
probably benign |
0.11 |
|
R9691:Dnajc13
|
UTSW |
9 |
104,042,211 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0017:Dnajc13
|
UTSW |
9 |
104,115,677 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
X0028:Dnajc13
|
UTSW |
9 |
104,042,217 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTACAGTCATGTGTAGCCAAGTTC -3'
(R):5'- TGGTCCTTTCAGCAGTGATTAC -3'
Sequencing Primer
(F):5'- AGATCTATCTCAGGTCCTCAGG -3'
(R):5'- GTCCTTTCAGCAGTGATTACATAGTC -3'
|
| Posted On |
2016-04-15 |
Incidental Mutation