Incidental Mutation 'R4960:Anapc1'
| ID |
382232 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Anapc1
|
| Ensembl Gene |
ENSMUSG00000014355 |
| Gene Name |
anaphase promoting complex subunit 1 |
| Synonyms |
Apc1, tsg24, Mcpr, 2610021O03Rik |
| MMRRC Submission |
042557-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4960 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
128452024-128529311 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to T
at 128526514 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Methionine
at position 95
(V95M)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000105962
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000014499]
[ENSMUST00000110332]
[ENSMUST00000110333]
|
| AlphaFold |
P53995 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000014499
AA Change: V95M
PolyPhen 2
Score 0.014 (Sensitivity: 0.96; Specificity: 0.79)
|
| SMART Domains |
Protein: ENSMUSP00000014499
Gene: ENSMUSG00000014355
AA Change: V95M
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ANAPC1
|
150 |
214 |
1.7e-13 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
low complexity region
|
1404 |
1415 |
N/A |
INTRINSIC |
|
Pfam:PC_rep
|
1467 |
1501 |
8.3e-8 |
PFAM |
|
low complexity region
|
1516 |
1528 |
N/A |
INTRINSIC |
|
low complexity region
|
1924 |
1936 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110332
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000110333
AA Change: V95M
PolyPhen 2
Score 0.235 (Sensitivity: 0.91; Specificity: 0.88)
|
| SMART Domains |
Protein: ENSMUSP00000105962
Gene: ENSMUSG00000014355
AA Change: V95M
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Apc1
|
149 |
227 |
1.7e-22 |
PFAM |
|
low complexity region
|
323 |
345 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134485
|
| Coding Region Coverage |
- 1x: 99.3%
- 3x: 98.5%
- 10x: 96.8%
- 20x: 93.8%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a subunit of the anaphase-promoting complex. This complex is an E3 ubiquitin ligase that regulates progression through the metaphase to anaphase portion of the cell cycle by ubiquitinating proteins which targets them for degradation. [provided by RefSeq, Dec 2011]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abcc9 |
A |
T |
6: 142,566,509 (GRCm39) |
|
probably null |
Het |
| Abtb3 |
A |
C |
10: 85,487,526 (GRCm39) |
N998T |
probably benign |
Het |
| Adamts20 |
T |
C |
15: 94,277,655 (GRCm39) |
H269R |
probably benign |
Het |
| Adamtsl1 |
C |
T |
4: 86,342,410 (GRCm39) |
Q1642* |
probably null |
Het |
| Adamtsl3 |
A |
C |
7: 82,216,185 (GRCm39) |
T863P |
probably damaging |
Het |
| Adcy3 |
G |
T |
12: 4,184,896 (GRCm39) |
V191L |
probably benign |
Het |
| Akap9 |
G |
T |
5: 4,007,664 (GRCm39) |
R244L |
probably benign |
Het |
| Arhgap17 |
G |
T |
7: 122,886,149 (GRCm39) |
|
probably benign |
Het |
| Art2b |
T |
A |
7: 101,229,437 (GRCm39) |
Y154F |
probably damaging |
Het |
| Atrn |
C |
T |
2: 130,836,967 (GRCm39) |
R1144* |
probably null |
Het |
| Atxn3 |
T |
C |
12: 101,914,638 (GRCm39) |
S29G |
possibly damaging |
Het |
| Batf3 |
C |
T |
1: 190,830,707 (GRCm39) |
P18S |
probably benign |
Het |
| Bmal1 |
T |
A |
7: 112,898,642 (GRCm39) |
|
probably null |
Het |
| Bmpr1b |
A |
T |
3: 141,576,546 (GRCm39) |
C96S |
probably damaging |
Het |
| Bola1 |
A |
G |
3: 96,104,370 (GRCm39) |
S75P |
probably benign |
Het |
| Cela3a |
G |
A |
4: 137,129,959 (GRCm39) |
R221* |
probably null |
Het |
| Chat |
A |
G |
14: 32,142,771 (GRCm39) |
V406A |
possibly damaging |
Het |
| Chd1 |
T |
A |
17: 15,962,493 (GRCm39) |
M750K |
probably damaging |
Het |
| Clip1 |
T |
A |
5: 123,792,066 (GRCm39) |
K35* |
probably null |
Het |
| Cnr2 |
G |
A |
4: 135,644,918 (GRCm39) |
G332D |
probably benign |
Het |
| Cnrip1 |
A |
G |
11: 17,002,228 (GRCm39) |
D20G |
probably damaging |
Het |
| Col2a1 |
T |
C |
15: 97,874,030 (GRCm39) |
Y1384C |
unknown |
Het |
| Col6a3 |
T |
A |
1: 90,731,940 (GRCm39) |
I831F |
probably damaging |
Het |
| Cp |
G |
A |
3: 20,027,961 (GRCm39) |
V456I |
probably damaging |
Het |
| Cspp1 |
T |
A |
1: 10,196,688 (GRCm39) |
N900K |
probably damaging |
Het |
| Ctbp2 |
T |
C |
7: 132,615,967 (GRCm39) |
I323V |
probably benign |
Het |
| Ctnna2 |
C |
T |
6: 77,630,094 (GRCm39) |
R120H |
probably damaging |
Het |
| Cyp2a12 |
A |
G |
7: 26,733,575 (GRCm39) |
H318R |
probably benign |
Het |
| Cyp2c66 |
A |
T |
19: 39,151,766 (GRCm39) |
|
probably null |
Het |
| Cyp2j8 |
T |
C |
4: 96,395,614 (GRCm39) |
T4A |
probably benign |
Het |
| Cyp4v3 |
A |
G |
8: 45,773,674 (GRCm39) |
V165A |
possibly damaging |
Het |
| D5Ertd579e |
G |
A |
5: 36,773,571 (GRCm39) |
R275* |
probably null |
Het |
| Deup1 |
G |
T |
9: 15,512,264 (GRCm39) |
Q160K |
possibly damaging |
Het |
| Dhx36 |
A |
T |
3: 62,404,280 (GRCm39) |
I221K |
probably damaging |
Het |
| Dnah7b |
T |
A |
1: 46,272,886 (GRCm39) |
M2338K |
probably benign |
Het |
| Dync2li1 |
T |
G |
17: 84,940,969 (GRCm39) |
L62V |
probably benign |
Het |
| Ephb3 |
A |
G |
16: 21,039,245 (GRCm39) |
K367R |
probably benign |
Het |
| Etv3 |
A |
G |
3: 87,435,368 (GRCm39) |
K80E |
probably damaging |
Het |
| Flacc1 |
T |
A |
1: 58,706,965 (GRCm39) |
E234V |
probably damaging |
Het |
| Gdap1l1 |
T |
C |
2: 163,295,779 (GRCm39) |
F346L |
probably benign |
Het |
| Gm4787 |
C |
T |
12: 81,426,090 (GRCm39) |
V23M |
probably damaging |
Het |
| Greb1l |
T |
A |
18: 10,547,306 (GRCm39) |
I1508N |
probably damaging |
Het |
| Heatr5b |
G |
A |
17: 79,139,013 (GRCm39) |
T43I |
probably benign |
Het |
| Hephl1 |
T |
C |
9: 14,997,586 (GRCm39) |
Y360C |
probably damaging |
Het |
| Itgam |
A |
C |
7: 127,715,012 (GRCm39) |
T865P |
possibly damaging |
Het |
| Kcnma1 |
T |
C |
14: 24,054,186 (GRCm39) |
|
probably benign |
Het |
| Kidins220 |
T |
A |
12: 25,042,259 (GRCm39) |
C185* |
probably null |
Het |
| Klhl35 |
G |
T |
7: 99,118,275 (GRCm39) |
G273V |
probably damaging |
Het |
| Lama5 |
A |
G |
2: 179,850,045 (GRCm39) |
|
probably null |
Het |
| Lamc3 |
A |
G |
2: 31,805,966 (GRCm39) |
Q689R |
probably benign |
Het |
| Lnx2 |
C |
T |
5: 146,955,850 (GRCm39) |
V649I |
probably benign |
Het |
| Lrrc43 |
A |
G |
5: 123,637,675 (GRCm39) |
I281V |
probably benign |
Het |
| Ly6g6d |
C |
A |
17: 35,290,730 (GRCm39) |
A67S |
probably benign |
Het |
| Map1b |
A |
G |
13: 99,568,720 (GRCm39) |
S1334P |
probably benign |
Het |
| Mast1 |
T |
A |
8: 85,644,500 (GRCm39) |
T810S |
probably benign |
Het |
| Matcap1 |
G |
T |
8: 106,009,843 (GRCm39) |
R369S |
probably damaging |
Het |
| Mbnl1 |
A |
G |
3: 60,503,117 (GRCm39) |
M1V |
probably null |
Het |
| Mc5r |
T |
G |
18: 68,471,890 (GRCm39) |
M83R |
possibly damaging |
Het |
| Mkln1 |
T |
C |
6: 31,435,941 (GRCm39) |
F300S |
probably damaging |
Het |
| Mrgpre |
A |
T |
7: 143,335,088 (GRCm39) |
C138* |
probably null |
Het |
| Mtarc2 |
T |
A |
1: 184,566,116 (GRCm39) |
M186L |
probably benign |
Het |
| Ncbp1 |
C |
T |
4: 46,165,273 (GRCm39) |
Q529* |
probably null |
Het |
| Nherf1 |
A |
G |
11: 115,067,289 (GRCm39) |
D180G |
probably benign |
Het |
| Nrcam |
A |
G |
12: 44,613,082 (GRCm39) |
D591G |
probably benign |
Het |
| Nrxn3 |
A |
T |
12: 88,761,971 (GRCm39) |
H6L |
possibly damaging |
Het |
| Nsmaf |
T |
A |
4: 6,423,342 (GRCm39) |
D342V |
probably damaging |
Het |
| Oip5 |
TGAGAAA |
T |
2: 119,448,342 (GRCm39) |
|
probably benign |
Het |
| Omt2a |
T |
A |
9: 78,220,305 (GRCm39) |
E31D |
possibly damaging |
Het |
| Or4f62 |
A |
G |
2: 111,986,697 (GRCm39) |
T134A |
probably benign |
Het |
| Or52n2b |
A |
G |
7: 104,565,915 (GRCm39) |
I196T |
probably benign |
Het |
| Or5ac20 |
A |
G |
16: 59,104,348 (GRCm39) |
S171P |
probably benign |
Het |
| Or6c88 |
A |
C |
10: 129,406,895 (GRCm39) |
I124L |
probably damaging |
Het |
| Or9a2 |
C |
A |
6: 41,749,003 (GRCm39) |
V77F |
probably damaging |
Het |
| Phyhipl |
A |
G |
10: 70,404,815 (GRCm39) |
V131A |
probably benign |
Het |
| Pik3r5 |
A |
G |
11: 68,384,464 (GRCm39) |
M619V |
probably benign |
Het |
| Pramel19 |
T |
C |
4: 101,798,661 (GRCm39) |
Y211H |
probably benign |
Het |
| Ptprg |
A |
T |
14: 12,237,837 (GRCm38) |
E1431D |
probably benign |
Het |
| Rnf20 |
A |
G |
4: 49,638,029 (GRCm39) |
T85A |
probably damaging |
Het |
| Rtn3 |
A |
T |
19: 7,433,886 (GRCm39) |
I683K |
probably damaging |
Het |
| Rwdd3 |
A |
G |
3: 120,952,470 (GRCm39) |
F174L |
probably damaging |
Het |
| Ryr1 |
T |
C |
7: 28,778,208 (GRCm39) |
Q2096R |
possibly damaging |
Het |
| Scrn1 |
T |
C |
6: 54,511,407 (GRCm39) |
D111G |
probably damaging |
Het |
| Sema3e |
A |
G |
5: 14,302,646 (GRCm39) |
R724G |
possibly damaging |
Het |
| She |
A |
G |
3: 89,741,544 (GRCm39) |
M232V |
possibly damaging |
Het |
| Skic3 |
T |
A |
13: 76,333,275 (GRCm39) |
V1508E |
possibly damaging |
Het |
| Slc25a54 |
A |
T |
3: 109,020,132 (GRCm39) |
N382I |
possibly damaging |
Het |
| Slc26a2 |
T |
C |
18: 61,331,875 (GRCm39) |
M519V |
probably damaging |
Het |
| Slc9a1 |
T |
A |
4: 133,097,967 (GRCm39) |
L38H |
probably damaging |
Het |
| Snap47 |
A |
T |
11: 59,319,369 (GRCm39) |
D256E |
probably damaging |
Het |
| Tacc3 |
A |
G |
5: 33,829,326 (GRCm39) |
T610A |
probably benign |
Het |
| Tbc1d30 |
G |
A |
10: 121,103,121 (GRCm39) |
T637M |
probably benign |
Het |
| Tbcd |
T |
A |
11: 121,464,681 (GRCm39) |
M572K |
probably benign |
Het |
| Thoc7 |
A |
T |
14: 13,953,460 (GRCm38) |
D68E |
probably benign |
Het |
| Tmpo |
G |
A |
10: 90,989,171 (GRCm39) |
T250M |
probably damaging |
Het |
| Tmtc1 |
TGTCCGCCAGGCCCTTGCCCCAGAAGTC |
TGTC |
6: 148,345,445 (GRCm39) |
|
probably benign |
Het |
| Tnfaip1 |
A |
T |
11: 78,418,396 (GRCm39) |
C224S |
possibly damaging |
Het |
| Tshz1 |
T |
C |
18: 84,032,987 (GRCm39) |
T474A |
probably benign |
Het |
| Tspoap1 |
C |
T |
11: 87,657,222 (GRCm39) |
Q345* |
probably null |
Het |
| Ttc21a |
A |
G |
9: 119,774,067 (GRCm39) |
E258G |
possibly damaging |
Het |
| Ttyh1 |
T |
C |
7: 4,131,225 (GRCm39) |
L232P |
probably damaging |
Het |
| Usp2 |
T |
A |
9: 43,987,110 (GRCm39) |
L136Q |
probably damaging |
Het |
| Usp31 |
T |
C |
7: 121,247,868 (GRCm39) |
S1192G |
probably damaging |
Het |
|
| Other mutations in Anapc1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00232:Anapc1
|
APN |
2 |
128,487,050 (GRCm39) |
splice site |
probably benign |
|
|
IGL00704:Anapc1
|
APN |
2 |
128,505,904 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
IGL01023:Anapc1
|
APN |
2 |
128,471,649 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01432:Anapc1
|
APN |
2 |
128,475,328 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01549:Anapc1
|
APN |
2 |
128,495,090 (GRCm39) |
missense |
probably benign |
|
|
IGL02089:Anapc1
|
APN |
2 |
128,505,853 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02275:Anapc1
|
APN |
2 |
128,501,772 (GRCm39) |
missense |
probably benign |
|
|
IGL02570:Anapc1
|
APN |
2 |
128,487,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02597:Anapc1
|
APN |
2 |
128,465,851 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL02726:Anapc1
|
APN |
2 |
128,501,705 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL03265:Anapc1
|
APN |
2 |
128,469,117 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03304:Anapc1
|
APN |
2 |
128,469,033 (GRCm39) |
splice site |
probably benign |
|
|
IGL03327:Anapc1
|
APN |
2 |
128,465,854 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0023:Anapc1
|
UTSW |
2 |
128,520,138 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0027:Anapc1
|
UTSW |
2 |
128,483,431 (GRCm39) |
missense |
possibly damaging |
0.96 |
|
R0084:Anapc1
|
UTSW |
2 |
128,465,886 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0103:Anapc1
|
UTSW |
2 |
128,522,372 (GRCm39) |
splice site |
probably benign |
|
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0109:Anapc1
|
UTSW |
2 |
128,476,613 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0241:Anapc1
|
UTSW |
2 |
128,470,549 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0255:Anapc1
|
UTSW |
2 |
128,476,631 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0377:Anapc1
|
UTSW |
2 |
128,483,260 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0467:Anapc1
|
UTSW |
2 |
128,510,963 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0514:Anapc1
|
UTSW |
2 |
128,474,575 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0591:Anapc1
|
UTSW |
2 |
128,461,252 (GRCm39) |
missense |
probably benign |
0.17 |
|
R0919:Anapc1
|
UTSW |
2 |
128,459,651 (GRCm39) |
missense |
probably benign |
|
|
R1175:Anapc1
|
UTSW |
2 |
128,522,108 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1473:Anapc1
|
UTSW |
2 |
128,459,617 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R1547:Anapc1
|
UTSW |
2 |
128,459,476 (GRCm39) |
missense |
probably benign |
0.44 |
|
R1556:Anapc1
|
UTSW |
2 |
128,466,819 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1567:Anapc1
|
UTSW |
2 |
128,459,636 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1635:Anapc1
|
UTSW |
2 |
128,470,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1645:Anapc1
|
UTSW |
2 |
128,500,166 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1677:Anapc1
|
UTSW |
2 |
128,518,128 (GRCm39) |
missense |
probably benign |
0.09 |
|
R1854:Anapc1
|
UTSW |
2 |
128,517,810 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1856:Anapc1
|
UTSW |
2 |
128,501,708 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1959:Anapc1
|
UTSW |
2 |
128,475,335 (GRCm39) |
missense |
probably benign |
0.36 |
|
R1984:Anapc1
|
UTSW |
2 |
128,511,608 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R2034:Anapc1
|
UTSW |
2 |
128,490,378 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2283:Anapc1
|
UTSW |
2 |
128,484,468 (GRCm39) |
missense |
probably benign |
0.23 |
|
R2928:Anapc1
|
UTSW |
2 |
128,522,057 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3547:Anapc1
|
UTSW |
2 |
128,484,602 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R3904:Anapc1
|
UTSW |
2 |
128,484,439 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4156:Anapc1
|
UTSW |
2 |
128,469,149 (GRCm39) |
intron |
probably benign |
|
|
R4359:Anapc1
|
UTSW |
2 |
128,465,476 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
R4392:Anapc1
|
UTSW |
2 |
128,518,169 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4574:Anapc1
|
UTSW |
2 |
128,469,115 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4682:Anapc1
|
UTSW |
2 |
128,505,925 (GRCm39) |
missense |
probably benign |
0.05 |
|
R4770:Anapc1
|
UTSW |
2 |
128,527,980 (GRCm39) |
splice site |
probably benign |
|
|
R4824:Anapc1
|
UTSW |
2 |
128,470,610 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R5016:Anapc1
|
UTSW |
2 |
128,449,095 (GRCm39) |
unclassified |
probably benign |
|
|
R5063:Anapc1
|
UTSW |
2 |
128,471,469 (GRCm39) |
missense |
possibly damaging |
0.48 |
|
R5128:Anapc1
|
UTSW |
2 |
128,501,837 (GRCm39) |
missense |
probably benign |
|
|
R5271:Anapc1
|
UTSW |
2 |
128,527,905 (GRCm39) |
nonsense |
probably null |
|
|
R5363:Anapc1
|
UTSW |
2 |
128,492,114 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5469:Anapc1
|
UTSW |
2 |
128,517,621 (GRCm39) |
nonsense |
probably null |
|
|
R5473:Anapc1
|
UTSW |
2 |
128,449,115 (GRCm39) |
unclassified |
probably benign |
|
|
R5559:Anapc1
|
UTSW |
2 |
128,522,354 (GRCm39) |
nonsense |
probably null |
|
|
R5631:Anapc1
|
UTSW |
2 |
128,499,137 (GRCm39) |
missense |
possibly damaging |
0.85 |
|
R5747:Anapc1
|
UTSW |
2 |
128,466,836 (GRCm39) |
missense |
probably benign |
0.19 |
|
R5840:Anapc1
|
UTSW |
2 |
128,448,957 (GRCm39) |
unclassified |
probably benign |
|
|
R6226:Anapc1
|
UTSW |
2 |
128,492,292 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6526:Anapc1
|
UTSW |
2 |
128,514,055 (GRCm39) |
nonsense |
probably null |
|
|
R6561:Anapc1
|
UTSW |
2 |
128,505,919 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6743:Anapc1
|
UTSW |
2 |
128,526,454 (GRCm39) |
nonsense |
probably null |
|
|
R6799:Anapc1
|
UTSW |
2 |
128,501,657 (GRCm39) |
missense |
probably null |
0.38 |
|
R6887:Anapc1
|
UTSW |
2 |
128,501,688 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R6978:Anapc1
|
UTSW |
2 |
128,511,820 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7011:Anapc1
|
UTSW |
2 |
128,490,601 (GRCm39) |
splice site |
probably null |
|
|
R7041:Anapc1
|
UTSW |
2 |
128,470,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R7047:Anapc1
|
UTSW |
2 |
128,457,350 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7074:Anapc1
|
UTSW |
2 |
128,520,194 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7109:Anapc1
|
UTSW |
2 |
128,516,522 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7123:Anapc1
|
UTSW |
2 |
128,454,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7309:Anapc1
|
UTSW |
2 |
128,516,604 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R7693:Anapc1
|
UTSW |
2 |
128,483,457 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R7839:Anapc1
|
UTSW |
2 |
128,526,528 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7847:Anapc1
|
UTSW |
2 |
128,511,828 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R7960:Anapc1
|
UTSW |
2 |
128,516,513 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8061:Anapc1
|
UTSW |
2 |
128,490,408 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R8127:Anapc1
|
UTSW |
2 |
128,474,547 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8228:Anapc1
|
UTSW |
2 |
128,461,837 (GRCm39) |
nonsense |
probably null |
|
|
R8402:Anapc1
|
UTSW |
2 |
128,472,148 (GRCm39) |
missense |
probably benign |
0.02 |
|
R8422:Anapc1
|
UTSW |
2 |
128,517,757 (GRCm39) |
missense |
probably benign |
|
|
R8425:Anapc1
|
UTSW |
2 |
128,511,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8469:Anapc1
|
UTSW |
2 |
128,500,264 (GRCm39) |
splice site |
probably null |
|
|
R8553:Anapc1
|
UTSW |
2 |
128,461,833 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8688:Anapc1
|
UTSW |
2 |
128,527,748 (GRCm39) |
missense |
probably benign |
0.19 |
|
R8699:Anapc1
|
UTSW |
2 |
128,483,373 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8719:Anapc1
|
UTSW |
2 |
128,483,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8775:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8775-TAIL:Anapc1
|
UTSW |
2 |
128,499,093 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8806:Anapc1
|
UTSW |
2 |
128,464,333 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R8973:Anapc1
|
UTSW |
2 |
128,505,952 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8977:Anapc1
|
UTSW |
2 |
128,483,322 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9000:Anapc1
|
UTSW |
2 |
128,476,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9080:Anapc1
|
UTSW |
2 |
128,464,426 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9203:Anapc1
|
UTSW |
2 |
128,465,422 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9314:Anapc1
|
UTSW |
2 |
128,464,420 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R9386:Anapc1
|
UTSW |
2 |
128,459,642 (GRCm39) |
missense |
probably benign |
0.08 |
|
R9415:Anapc1
|
UTSW |
2 |
128,476,598 (GRCm39) |
missense |
probably benign |
|
|
R9436:Anapc1
|
UTSW |
2 |
128,518,045 (GRCm39) |
missense |
probably benign |
|
|
R9516:Anapc1
|
UTSW |
2 |
128,517,633 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9563:Anapc1
|
UTSW |
2 |
128,505,980 (GRCm39) |
nonsense |
probably null |
|
|
R9572:Anapc1
|
UTSW |
2 |
128,505,976 (GRCm39) |
missense |
probably benign |
|
|
R9757:Anapc1
|
UTSW |
2 |
128,517,676 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9766:Anapc1
|
UTSW |
2 |
128,500,221 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0066:Anapc1
|
UTSW |
2 |
128,516,621 (GRCm39) |
missense |
probably benign |
0.10 |
|
| Predicted Primers |
PCR Primer
(F):5'- ACCAGCTGCTACAATTGTTACAC -3'
(R):5'- GTGCTCACCTATGTATTGCAATC -3'
Sequencing Primer
(F):5'- CAGCTGCTACAATTGTTACACTGTTG -3'
(R):5'- CACCTATGTATTGCAATCCTTGTAGG -3'
|
| Posted On |
2016-04-27 |
Incidental Mutation