Incidental Mutation 'R4946:Adgre1'
| ID |
383459 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Adgre1
|
| Ensembl Gene |
ENSMUSG00000004730 |
| Gene Name |
adhesion G protein-coupled receptor E1 |
| Synonyms |
DD7A5-7, EGF-TM7, Emr1, Ly71, F4/80, TM7LN3 |
| MMRRC Submission |
042543-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.190)
|
| Stock # |
R4946 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
17 |
| Chromosomal Location |
57665691-57790527 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to A
at 57750918 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Isoleucine
at position 531
(V531I)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000083971
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000004850]
[ENSMUST00000086763]
|
| AlphaFold |
Q61549 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000004850
AA Change: V531I
PolyPhen 2
Score 0.334 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000004850
Gene: ENSMUSG00000004730
AA Change: V531I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
32 |
N/A |
INTRINSIC |
|
EGF
|
35 |
80 |
1.43e-1 |
SMART |
|
EGF_CA
|
81 |
122 |
3.59e-7 |
SMART |
|
EGF_CA
|
133 |
172 |
4.56e-9 |
SMART |
|
EGF_CA
|
173 |
221 |
1.29e-8 |
SMART |
|
EGF_CA
|
222 |
271 |
2.31e-10 |
SMART |
|
EGF_CA
|
272 |
318 |
1.06e-9 |
SMART |
|
EGF_CA
|
319 |
367 |
1.18e-7 |
SMART |
|
GPS
|
591 |
641 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
644 |
885 |
2.1e-63 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000086763
AA Change: V531I
PolyPhen 2
Score 0.334 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000083971
Gene: ENSMUSG00000004730
AA Change: V531I
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
19 |
32 |
N/A |
INTRINSIC |
|
EGF
|
35 |
80 |
1.43e-1 |
SMART |
|
EGF_CA
|
81 |
122 |
3.59e-7 |
SMART |
|
EGF_CA
|
133 |
172 |
4.56e-9 |
SMART |
|
EGF_CA
|
173 |
221 |
1.29e-8 |
SMART |
|
EGF_CA
|
222 |
271 |
2.31e-10 |
SMART |
|
EGF_CA
|
272 |
318 |
1.06e-9 |
SMART |
|
EGF_CA
|
319 |
367 |
1.18e-7 |
SMART |
|
GPS
|
591 |
641 |
2.57e-19 |
SMART |
|
Pfam:7tm_2
|
644 |
885 |
2.1e-63 |
PFAM |
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 96.0%
- 20x: 91.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that has a domain resembling seven transmembrane G protein-coupled hormone receptors (7TM receptors) at its C-terminus. The N-terminus of the encoded protein has six EGF-like modules, separated from the transmembrane segments by a serine/threonine-rich domain, a feature reminiscent of mucin-like, single-span, integral membrane glycoproteins with adhesive properties. Multiple alternatively spliced transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jan 2012]
PHENOTYPE: Homozygous null mice fail to develop peripheral tolerance after inoculation with antigen because of a lack of efferent regulatory T cell development. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(4) : Targeted(3) Chemically induced(1)
|
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8a |
T |
C |
11: 109,977,300 (GRCm39) |
D98G |
probably damaging |
Het |
| Aldoart2 |
A |
G |
12: 55,612,801 (GRCm39) |
Q242R |
probably benign |
Het |
| Ank2 |
A |
T |
3: 126,735,589 (GRCm39) |
|
probably benign |
Het |
| Ank3 |
C |
T |
10: 69,733,947 (GRCm39) |
A737V |
probably damaging |
Het |
| Ankle2 |
A |
G |
5: 110,401,704 (GRCm39) |
I789V |
probably benign |
Het |
| Ankrd13c |
T |
C |
3: 157,711,410 (GRCm39) |
V510A |
probably damaging |
Het |
| Arid1b |
T |
A |
17: 5,393,118 (GRCm39) |
M2216K |
probably damaging |
Het |
| Arrdc1 |
A |
G |
2: 24,815,860 (GRCm39) |
V380A |
probably benign |
Het |
| B3galt1 |
C |
A |
2: 67,948,913 (GRCm39) |
N209K |
possibly damaging |
Het |
| Cd300c2 |
A |
T |
11: 114,887,731 (GRCm39) |
C224S |
probably benign |
Het |
| Cdk4 |
T |
C |
10: 126,900,759 (GRCm39) |
|
probably null |
Het |
| Cdk5rap1 |
T |
C |
2: 154,210,794 (GRCm39) |
T115A |
possibly damaging |
Het |
| Clvs1 |
A |
T |
4: 9,281,831 (GRCm39) |
R92* |
probably null |
Het |
| Cnga1 |
A |
G |
5: 72,762,107 (GRCm39) |
V469A |
probably damaging |
Het |
| Ctns |
A |
G |
11: 73,087,479 (GRCm39) |
F16L |
probably benign |
Het |
| Dlg5 |
A |
T |
14: 24,204,429 (GRCm39) |
C1299S |
probably damaging |
Het |
| Dnah3 |
T |
A |
7: 119,530,783 (GRCm39) |
Y3690F |
probably damaging |
Het |
| Dnah5 |
A |
G |
15: 28,326,703 (GRCm39) |
M1971V |
probably damaging |
Het |
| Dnah5 |
G |
A |
15: 28,388,050 (GRCm39) |
V3170M |
probably damaging |
Het |
| Dpp8 |
T |
C |
9: 64,963,200 (GRCm39) |
Y485H |
probably benign |
Het |
| Dsc2 |
T |
C |
18: 20,183,214 (GRCm39) |
D68G |
probably damaging |
Het |
| Eeig2 |
A |
G |
3: 108,887,544 (GRCm39) |
V240A |
probably benign |
Het |
| Elavl1 |
A |
T |
8: 4,351,752 (GRCm39) |
D121E |
probably benign |
Het |
| Ermap |
A |
G |
4: 119,040,505 (GRCm39) |
V311A |
probably damaging |
Het |
| Fbxw11 |
C |
T |
11: 32,689,226 (GRCm39) |
R437C |
probably damaging |
Het |
| Gas2l3 |
T |
C |
10: 89,249,634 (GRCm39) |
M495V |
probably benign |
Het |
| Hacd1 |
C |
T |
2: 14,049,948 (GRCm39) |
|
probably null |
Het |
| Itgav |
A |
G |
2: 83,619,327 (GRCm39) |
R596G |
probably benign |
Het |
| Kars1 |
T |
C |
8: 112,728,352 (GRCm39) |
H215R |
possibly damaging |
Het |
| Kif26a |
G |
A |
12: 112,144,228 (GRCm39) |
R1494H |
probably damaging |
Het |
| Klf12 |
G |
A |
14: 100,260,393 (GRCm39) |
S112L |
possibly damaging |
Het |
| Krt77 |
T |
C |
15: 101,777,998 (GRCm39) |
Y19C |
unknown |
Het |
| Lrrc4c |
A |
G |
2: 97,460,834 (GRCm39) |
T487A |
probably benign |
Het |
| Lrrn1 |
A |
G |
6: 107,545,851 (GRCm39) |
M550V |
probably benign |
Het |
| Lsr |
C |
A |
7: 30,657,634 (GRCm39) |
R442L |
probably benign |
Het |
| Lysmd2 |
A |
C |
9: 75,542,728 (GRCm39) |
T112P |
probably damaging |
Het |
| Mctp2 |
A |
T |
7: 71,909,017 (GRCm39) |
S99T |
probably benign |
Het |
| Mettl4 |
A |
G |
17: 95,047,960 (GRCm39) |
V227A |
probably benign |
Het |
| Mill2 |
T |
A |
7: 18,590,608 (GRCm39) |
|
probably null |
Het |
| Mpp3 |
T |
C |
11: 101,895,848 (GRCm39) |
N476D |
probably benign |
Het |
| Mtmr6 |
C |
T |
14: 60,517,638 (GRCm39) |
P83L |
possibly damaging |
Het |
| Myh3 |
T |
C |
11: 66,984,364 (GRCm39) |
I1067T |
probably benign |
Het |
| Myh9 |
C |
A |
15: 77,657,540 (GRCm39) |
Q1068H |
probably damaging |
Het |
| Narf |
T |
A |
11: 121,141,179 (GRCm39) |
H304Q |
possibly damaging |
Het |
| Nfatc2ip |
G |
T |
7: 125,995,784 (GRCm39) |
P35Q |
possibly damaging |
Het |
| Npas3 |
C |
A |
12: 54,112,618 (GRCm39) |
P426Q |
probably damaging |
Het |
| Or10aa3 |
T |
G |
1: 173,878,400 (GRCm39) |
S154A |
possibly damaging |
Het |
| Or4e1 |
G |
A |
14: 52,700,740 (GRCm39) |
T242I |
probably damaging |
Het |
| Or4f4b |
T |
C |
2: 111,314,311 (GRCm39) |
Y207H |
possibly damaging |
Het |
| Or51i1 |
T |
A |
7: 103,671,219 (GRCm39) |
Q102L |
probably damaging |
Het |
| Or5p5 |
A |
G |
7: 107,414,589 (GRCm39) |
H266R |
possibly damaging |
Het |
| Pcdh10 |
A |
T |
3: 45,333,917 (GRCm39) |
E77V |
probably damaging |
Het |
| Pcnt |
C |
T |
10: 76,192,019 (GRCm39) |
R2764Q |
probably damaging |
Het |
| Pgbd5 |
T |
C |
8: 125,097,324 (GRCm39) |
D493G |
possibly damaging |
Het |
| Piezo2 |
G |
T |
18: 63,290,333 (GRCm39) |
T142N |
probably benign |
Het |
| Plcb1 |
A |
G |
2: 135,187,015 (GRCm39) |
I761V |
probably benign |
Het |
| Plekhg4 |
T |
G |
8: 106,108,628 (GRCm39) |
D1196E |
probably null |
Het |
| Pparg |
A |
G |
6: 115,427,989 (GRCm39) |
K159E |
probably damaging |
Het |
| Psmb1 |
A |
T |
17: 15,718,478 (GRCm39) |
M16K |
probably benign |
Het |
| Ptprq |
T |
C |
10: 107,361,595 (GRCm39) |
I2139V |
probably benign |
Het |
| Ralgapb |
T |
A |
2: 158,282,887 (GRCm39) |
S239T |
probably damaging |
Het |
| Serpina11 |
A |
G |
12: 103,950,923 (GRCm39) |
V266A |
probably damaging |
Het |
| Sf3a2 |
C |
G |
10: 80,639,947 (GRCm39) |
|
probably benign |
Het |
| Smim18 |
T |
C |
8: 34,232,587 (GRCm39) |
T11A |
possibly damaging |
Het |
| Snx6 |
G |
A |
12: 54,817,528 (GRCm39) |
T7I |
probably damaging |
Het |
| Srcin1 |
T |
A |
11: 97,442,768 (GRCm39) |
D75V |
probably damaging |
Het |
| Srsf12 |
T |
A |
4: 33,231,174 (GRCm39) |
S223T |
probably damaging |
Het |
| Taf4b |
G |
T |
18: 14,946,599 (GRCm39) |
C474F |
probably damaging |
Het |
| Tango6 |
T |
A |
8: 107,444,722 (GRCm39) |
C542* |
probably null |
Het |
| Tbc1d24 |
A |
G |
17: 24,427,510 (GRCm39) |
S151P |
possibly damaging |
Het |
| Tssk6 |
T |
C |
8: 70,355,714 (GRCm39) |
S253P |
probably benign |
Het |
| Ttc39c |
G |
A |
18: 12,857,999 (GRCm39) |
W300* |
probably null |
Het |
| Ttc6 |
T |
A |
12: 57,689,926 (GRCm39) |
W539R |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,582,770 (GRCm39) |
T22708A |
probably damaging |
Het |
| Ttn |
C |
A |
2: 76,749,053 (GRCm39) |
E3999* |
probably null |
Het |
| Vill |
T |
G |
9: 118,897,508 (GRCm39) |
L261R |
probably damaging |
Het |
| Vmn1r20 |
T |
C |
6: 57,409,159 (GRCm39) |
S162P |
probably damaging |
Het |
| Zfp516 |
T |
C |
18: 82,974,219 (GRCm39) |
I139T |
probably benign |
Het |
|
| Other mutations in Adgre1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00090:Adgre1
|
APN |
17 |
57,757,055 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL00966:Adgre1
|
APN |
17 |
57,726,335 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL01680:Adgre1
|
APN |
17 |
57,709,620 (GRCm39) |
missense |
unknown |
|
|
IGL01724:Adgre1
|
APN |
17 |
57,751,064 (GRCm39) |
nonsense |
probably null |
|
|
IGL02172:Adgre1
|
APN |
17 |
57,785,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02260:Adgre1
|
APN |
17 |
57,754,891 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02272:Adgre1
|
APN |
17 |
57,757,021 (GRCm39) |
nonsense |
probably null |
|
|
IGL02336:Adgre1
|
APN |
17 |
57,718,024 (GRCm39) |
nonsense |
probably null |
|
|
IGL02346:Adgre1
|
APN |
17 |
57,750,919 (GRCm39) |
missense |
probably benign |
0.15 |
|
IGL02398:Adgre1
|
APN |
17 |
57,709,824 (GRCm39) |
nonsense |
probably null |
|
|
IGL02618:Adgre1
|
APN |
17 |
57,751,021 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02690:Adgre1
|
APN |
17 |
57,787,921 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02936:Adgre1
|
APN |
17 |
57,785,833 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL03112:Adgre1
|
APN |
17 |
57,755,029 (GRCm39) |
splice site |
probably null |
|
|
IGL03350:Adgre1
|
APN |
17 |
57,708,908 (GRCm39) |
missense |
probably benign |
0.16 |
|
F480
|
UTSW |
17 |
57,751,063 (GRCm39) |
missense |
probably damaging |
1.00 |
|
lomax
|
UTSW |
17 |
57,709,811 (GRCm39) |
missense |
unknown |
|
|
Onion
|
UTSW |
17 |
57,709,841 (GRCm39) |
nonsense |
probably null |
|
|
Scallion
|
UTSW |
17 |
57,708,977 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0049:Adgre1
|
UTSW |
17 |
57,709,841 (GRCm39) |
nonsense |
probably null |
|
|
R0153:Adgre1
|
UTSW |
17 |
57,750,939 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R0277:Adgre1
|
UTSW |
17 |
57,751,060 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0278:Adgre1
|
UTSW |
17 |
57,754,872 (GRCm39) |
missense |
probably benign |
0.07 |
|
R0323:Adgre1
|
UTSW |
17 |
57,751,060 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0389:Adgre1
|
UTSW |
17 |
57,713,839 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R0492:Adgre1
|
UTSW |
17 |
57,709,742 (GRCm39) |
missense |
unknown |
|
|
R0621:Adgre1
|
UTSW |
17 |
57,748,359 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0647:Adgre1
|
UTSW |
17 |
57,718,003 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1310:Adgre1
|
UTSW |
17 |
57,754,936 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1601:Adgre1
|
UTSW |
17 |
57,748,353 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1689:Adgre1
|
UTSW |
17 |
57,756,921 (GRCm39) |
missense |
probably benign |
0.31 |
|
R1708:Adgre1
|
UTSW |
17 |
57,708,974 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R1796:Adgre1
|
UTSW |
17 |
57,748,350 (GRCm39) |
missense |
probably benign |
0.43 |
|
R1839:Adgre1
|
UTSW |
17 |
57,748,299 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1860:Adgre1
|
UTSW |
17 |
57,748,363 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2165:Adgre1
|
UTSW |
17 |
57,726,338 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2219:Adgre1
|
UTSW |
17 |
57,708,912 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R2519:Adgre1
|
UTSW |
17 |
57,717,956 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3874:Adgre1
|
UTSW |
17 |
57,708,925 (GRCm39) |
missense |
probably benign |
0.08 |
|
R3911:Adgre1
|
UTSW |
17 |
57,754,860 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4190:Adgre1
|
UTSW |
17 |
57,709,811 (GRCm39) |
missense |
unknown |
|
|
R4439:Adgre1
|
UTSW |
17 |
57,754,954 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4513:Adgre1
|
UTSW |
17 |
57,717,947 (GRCm39) |
missense |
probably benign |
0.34 |
|
R4529:Adgre1
|
UTSW |
17 |
57,727,519 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R4543:Adgre1
|
UTSW |
17 |
57,713,874 (GRCm39) |
missense |
probably benign |
0.07 |
|
R4610:Adgre1
|
UTSW |
17 |
57,757,073 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
R4665:Adgre1
|
UTSW |
17 |
57,787,947 (GRCm39) |
missense |
probably benign |
0.20 |
|
R4911:Adgre1
|
UTSW |
17 |
57,754,832 (GRCm39) |
missense |
possibly damaging |
0.57 |
|
R4928:Adgre1
|
UTSW |
17 |
57,751,064 (GRCm39) |
nonsense |
probably null |
|
|
R4942:Adgre1
|
UTSW |
17 |
57,713,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4953:Adgre1
|
UTSW |
17 |
57,748,321 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5107:Adgre1
|
UTSW |
17 |
57,708,977 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5366:Adgre1
|
UTSW |
17 |
57,709,817 (GRCm39) |
missense |
probably benign |
0.39 |
|
R5590:Adgre1
|
UTSW |
17 |
57,752,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5619:Adgre1
|
UTSW |
17 |
57,727,437 (GRCm39) |
missense |
probably benign |
0.15 |
|
R5699:Adgre1
|
UTSW |
17 |
57,788,007 (GRCm39) |
missense |
probably benign |
0.43 |
|
R5734:Adgre1
|
UTSW |
17 |
57,750,990 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5860:Adgre1
|
UTSW |
17 |
57,752,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6039:Adgre1
|
UTSW |
17 |
57,713,859 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6039:Adgre1
|
UTSW |
17 |
57,713,859 (GRCm39) |
missense |
probably benign |
0.28 |
|
R6149:Adgre1
|
UTSW |
17 |
57,752,018 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6478:Adgre1
|
UTSW |
17 |
57,708,955 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6709:Adgre1
|
UTSW |
17 |
57,713,917 (GRCm39) |
missense |
probably benign |
0.10 |
|
R6864:Adgre1
|
UTSW |
17 |
57,785,879 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6945:Adgre1
|
UTSW |
17 |
57,727,399 (GRCm39) |
missense |
probably benign |
0.39 |
|
R6945:Adgre1
|
UTSW |
17 |
57,717,844 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6988:Adgre1
|
UTSW |
17 |
57,715,445 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7019:Adgre1
|
UTSW |
17 |
57,717,945 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7154:Adgre1
|
UTSW |
17 |
57,751,087 (GRCm39) |
splice site |
probably null |
|
|
R7347:Adgre1
|
UTSW |
17 |
57,727,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7459:Adgre1
|
UTSW |
17 |
57,756,933 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7709:Adgre1
|
UTSW |
17 |
57,709,519 (GRCm39) |
missense |
unknown |
|
|
R7939:Adgre1
|
UTSW |
17 |
57,756,938 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7977:Adgre1
|
UTSW |
17 |
57,754,987 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R7987:Adgre1
|
UTSW |
17 |
57,754,987 (GRCm39) |
missense |
possibly damaging |
0.54 |
|
R8187:Adgre1
|
UTSW |
17 |
57,727,349 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8210:Adgre1
|
UTSW |
17 |
57,752,061 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8223:Adgre1
|
UTSW |
17 |
57,668,692 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8344:Adgre1
|
UTSW |
17 |
57,715,459 (GRCm39) |
missense |
probably benign |
0.12 |
|
R8698:Adgre1
|
UTSW |
17 |
57,709,003 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9236:Adgre1
|
UTSW |
17 |
57,709,782 (GRCm39) |
nonsense |
probably null |
|
|
R9262:Adgre1
|
UTSW |
17 |
57,754,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9303:Adgre1
|
UTSW |
17 |
57,748,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9305:Adgre1
|
UTSW |
17 |
57,748,275 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9605:Adgre1
|
UTSW |
17 |
57,718,083 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9661:Adgre1
|
UTSW |
17 |
57,748,368 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R9678:Adgre1
|
UTSW |
17 |
57,750,997 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9751:Adgre1
|
UTSW |
17 |
57,757,101 (GRCm39) |
missense |
probably null |
0.06 |
|
R9785:Adgre1
|
UTSW |
17 |
57,785,930 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Adgre1
|
UTSW |
17 |
57,668,729 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
Z1177:Adgre1
|
UTSW |
17 |
57,726,374 (GRCm39) |
missense |
probably damaging |
0.96 |
|
| Predicted Primers |
PCR Primer
(F):5'- CCTGCCTCAACTGATCTGAAAATTC -3'
(R):5'- AAACCTGGATGTGCTGGAGG -3'
Sequencing Primer
(F):5'- AGAGTCTGTGTATGTACATGTCAC -3'
(R):5'- CTGGAGGGTATAGATAATAGGCTTG -3'
|
| Posted On |
2016-04-27 |
Incidental Mutation