Incidental Mutation 'R4946:Dsc2'
| ID |
383463 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dsc2
|
| Ensembl Gene |
ENSMUSG00000024331 |
| Gene Name |
desmocollin 2 |
| Synonyms |
Dsc2a, Dsc2b |
| MMRRC Submission |
042543-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R4946 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
18 |
| Chromosomal Location |
20163690-20192611 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 20183214 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 68
(D68G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000074702
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000039247]
[ENSMUST00000075214]
[ENSMUST00000128464]
|
| AlphaFold |
P55292 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000039247
AA Change: D68G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000042905
Gene: ENSMUSG00000024331
AA Change: D68G
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000075214
AA Change: D68G
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000074702
Gene: ENSMUSG00000024331
AA Change: D68G
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
28 |
N/A |
INTRINSIC |
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
CA
|
156 |
241 |
4.66e-11 |
SMART |
|
CA
|
265 |
353 |
1.87e-24 |
SMART |
|
low complexity region
|
358 |
372 |
N/A |
INTRINSIC |
|
CA
|
376 |
470 |
1.27e-12 |
SMART |
|
CA
|
493 |
575 |
4.14e-17 |
SMART |
|
CA
|
594 |
676 |
1.49e-1 |
SMART |
|
transmembrane domain
|
696 |
718 |
N/A |
INTRINSIC |
|
Pfam:Cadherin_C
|
730 |
901 |
3.7e-9 |
PFAM |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000128464
AA Change: D68G
PolyPhen 2
Score 0.993 (Sensitivity: 0.70; Specificity: 0.97)
|
| SMART Domains |
Protein: ENSMUSP00000123010
Gene: ENSMUSG00000024331
AA Change: D68G
| Domain | Start | End | E-Value | Type |
|---|
|
Cadherin_pro
|
31 |
113 |
2.82e-37 |
SMART |
|
| Coding Region Coverage |
- 1x: 99.0%
- 3x: 98.2%
- 10x: 96.0%
- 20x: 91.3%
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: This gene encodes a member of the desmocollin protein subfamily. Desmocollins are cadherin-like transmembrane glycoproteins that are major components of the desmosome. Desmosomes are cell-cell junctions that help resist shearing forces and are found in high concentrations in cells subject to mechanical stress. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Dec 2015]
|
| Allele List at MGI |
All alleles(2) : Targeted, other(2) |
| Other mutations in this stock |
Total: 78 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Abca8a |
T |
C |
11: 109,977,300 (GRCm39) |
D98G |
probably damaging |
Het |
| Adgre1 |
G |
A |
17: 57,750,918 (GRCm39) |
V531I |
probably benign |
Het |
| Aldoart2 |
A |
G |
12: 55,612,801 (GRCm39) |
Q242R |
probably benign |
Het |
| Ank2 |
A |
T |
3: 126,735,589 (GRCm39) |
|
probably benign |
Het |
| Ank3 |
C |
T |
10: 69,733,947 (GRCm39) |
A737V |
probably damaging |
Het |
| Ankle2 |
A |
G |
5: 110,401,704 (GRCm39) |
I789V |
probably benign |
Het |
| Ankrd13c |
T |
C |
3: 157,711,410 (GRCm39) |
V510A |
probably damaging |
Het |
| Arid1b |
T |
A |
17: 5,393,118 (GRCm39) |
M2216K |
probably damaging |
Het |
| Arrdc1 |
A |
G |
2: 24,815,860 (GRCm39) |
V380A |
probably benign |
Het |
| B3galt1 |
C |
A |
2: 67,948,913 (GRCm39) |
N209K |
possibly damaging |
Het |
| Cd300c2 |
A |
T |
11: 114,887,731 (GRCm39) |
C224S |
probably benign |
Het |
| Cdk4 |
T |
C |
10: 126,900,759 (GRCm39) |
|
probably null |
Het |
| Cdk5rap1 |
T |
C |
2: 154,210,794 (GRCm39) |
T115A |
possibly damaging |
Het |
| Clvs1 |
A |
T |
4: 9,281,831 (GRCm39) |
R92* |
probably null |
Het |
| Cnga1 |
A |
G |
5: 72,762,107 (GRCm39) |
V469A |
probably damaging |
Het |
| Ctns |
A |
G |
11: 73,087,479 (GRCm39) |
F16L |
probably benign |
Het |
| Dlg5 |
A |
T |
14: 24,204,429 (GRCm39) |
C1299S |
probably damaging |
Het |
| Dnah3 |
T |
A |
7: 119,530,783 (GRCm39) |
Y3690F |
probably damaging |
Het |
| Dnah5 |
A |
G |
15: 28,326,703 (GRCm39) |
M1971V |
probably damaging |
Het |
| Dnah5 |
G |
A |
15: 28,388,050 (GRCm39) |
V3170M |
probably damaging |
Het |
| Dpp8 |
T |
C |
9: 64,963,200 (GRCm39) |
Y485H |
probably benign |
Het |
| Eeig2 |
A |
G |
3: 108,887,544 (GRCm39) |
V240A |
probably benign |
Het |
| Elavl1 |
A |
T |
8: 4,351,752 (GRCm39) |
D121E |
probably benign |
Het |
| Ermap |
A |
G |
4: 119,040,505 (GRCm39) |
V311A |
probably damaging |
Het |
| Fbxw11 |
C |
T |
11: 32,689,226 (GRCm39) |
R437C |
probably damaging |
Het |
| Gas2l3 |
T |
C |
10: 89,249,634 (GRCm39) |
M495V |
probably benign |
Het |
| Hacd1 |
C |
T |
2: 14,049,948 (GRCm39) |
|
probably null |
Het |
| Itgav |
A |
G |
2: 83,619,327 (GRCm39) |
R596G |
probably benign |
Het |
| Kars1 |
T |
C |
8: 112,728,352 (GRCm39) |
H215R |
possibly damaging |
Het |
| Kif26a |
G |
A |
12: 112,144,228 (GRCm39) |
R1494H |
probably damaging |
Het |
| Klf12 |
G |
A |
14: 100,260,393 (GRCm39) |
S112L |
possibly damaging |
Het |
| Krt77 |
T |
C |
15: 101,777,998 (GRCm39) |
Y19C |
unknown |
Het |
| Lrrc4c |
A |
G |
2: 97,460,834 (GRCm39) |
T487A |
probably benign |
Het |
| Lrrn1 |
A |
G |
6: 107,545,851 (GRCm39) |
M550V |
probably benign |
Het |
| Lsr |
C |
A |
7: 30,657,634 (GRCm39) |
R442L |
probably benign |
Het |
| Lysmd2 |
A |
C |
9: 75,542,728 (GRCm39) |
T112P |
probably damaging |
Het |
| Mctp2 |
A |
T |
7: 71,909,017 (GRCm39) |
S99T |
probably benign |
Het |
| Mettl4 |
A |
G |
17: 95,047,960 (GRCm39) |
V227A |
probably benign |
Het |
| Mill2 |
T |
A |
7: 18,590,608 (GRCm39) |
|
probably null |
Het |
| Mpp3 |
T |
C |
11: 101,895,848 (GRCm39) |
N476D |
probably benign |
Het |
| Mtmr6 |
C |
T |
14: 60,517,638 (GRCm39) |
P83L |
possibly damaging |
Het |
| Myh3 |
T |
C |
11: 66,984,364 (GRCm39) |
I1067T |
probably benign |
Het |
| Myh9 |
C |
A |
15: 77,657,540 (GRCm39) |
Q1068H |
probably damaging |
Het |
| Narf |
T |
A |
11: 121,141,179 (GRCm39) |
H304Q |
possibly damaging |
Het |
| Nfatc2ip |
G |
T |
7: 125,995,784 (GRCm39) |
P35Q |
possibly damaging |
Het |
| Npas3 |
C |
A |
12: 54,112,618 (GRCm39) |
P426Q |
probably damaging |
Het |
| Or10aa3 |
T |
G |
1: 173,878,400 (GRCm39) |
S154A |
possibly damaging |
Het |
| Or4e1 |
G |
A |
14: 52,700,740 (GRCm39) |
T242I |
probably damaging |
Het |
| Or4f4b |
T |
C |
2: 111,314,311 (GRCm39) |
Y207H |
possibly damaging |
Het |
| Or51i1 |
T |
A |
7: 103,671,219 (GRCm39) |
Q102L |
probably damaging |
Het |
| Or5p5 |
A |
G |
7: 107,414,589 (GRCm39) |
H266R |
possibly damaging |
Het |
| Pcdh10 |
A |
T |
3: 45,333,917 (GRCm39) |
E77V |
probably damaging |
Het |
| Pcnt |
C |
T |
10: 76,192,019 (GRCm39) |
R2764Q |
probably damaging |
Het |
| Pgbd5 |
T |
C |
8: 125,097,324 (GRCm39) |
D493G |
possibly damaging |
Het |
| Piezo2 |
G |
T |
18: 63,290,333 (GRCm39) |
T142N |
probably benign |
Het |
| Plcb1 |
A |
G |
2: 135,187,015 (GRCm39) |
I761V |
probably benign |
Het |
| Plekhg4 |
T |
G |
8: 106,108,628 (GRCm39) |
D1196E |
probably null |
Het |
| Pparg |
A |
G |
6: 115,427,989 (GRCm39) |
K159E |
probably damaging |
Het |
| Psmb1 |
A |
T |
17: 15,718,478 (GRCm39) |
M16K |
probably benign |
Het |
| Ptprq |
T |
C |
10: 107,361,595 (GRCm39) |
I2139V |
probably benign |
Het |
| Ralgapb |
T |
A |
2: 158,282,887 (GRCm39) |
S239T |
probably damaging |
Het |
| Serpina11 |
A |
G |
12: 103,950,923 (GRCm39) |
V266A |
probably damaging |
Het |
| Sf3a2 |
C |
G |
10: 80,639,947 (GRCm39) |
|
probably benign |
Het |
| Smim18 |
T |
C |
8: 34,232,587 (GRCm39) |
T11A |
possibly damaging |
Het |
| Snx6 |
G |
A |
12: 54,817,528 (GRCm39) |
T7I |
probably damaging |
Het |
| Srcin1 |
T |
A |
11: 97,442,768 (GRCm39) |
D75V |
probably damaging |
Het |
| Srsf12 |
T |
A |
4: 33,231,174 (GRCm39) |
S223T |
probably damaging |
Het |
| Taf4b |
G |
T |
18: 14,946,599 (GRCm39) |
C474F |
probably damaging |
Het |
| Tango6 |
T |
A |
8: 107,444,722 (GRCm39) |
C542* |
probably null |
Het |
| Tbc1d24 |
A |
G |
17: 24,427,510 (GRCm39) |
S151P |
possibly damaging |
Het |
| Tssk6 |
T |
C |
8: 70,355,714 (GRCm39) |
S253P |
probably benign |
Het |
| Ttc39c |
G |
A |
18: 12,857,999 (GRCm39) |
W300* |
probably null |
Het |
| Ttc6 |
T |
A |
12: 57,689,926 (GRCm39) |
W539R |
probably benign |
Het |
| Ttn |
T |
C |
2: 76,582,770 (GRCm39) |
T22708A |
probably damaging |
Het |
| Ttn |
C |
A |
2: 76,749,053 (GRCm39) |
E3999* |
probably null |
Het |
| Vill |
T |
G |
9: 118,897,508 (GRCm39) |
L261R |
probably damaging |
Het |
| Vmn1r20 |
T |
C |
6: 57,409,159 (GRCm39) |
S162P |
probably damaging |
Het |
| Zfp516 |
T |
C |
18: 82,974,219 (GRCm39) |
I139T |
probably benign |
Het |
|
| Other mutations in Dsc2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00802:Dsc2
|
APN |
18 |
20,174,854 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL00826:Dsc2
|
APN |
18 |
20,168,372 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00852:Dsc2
|
APN |
18 |
20,167,740 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01082:Dsc2
|
APN |
18 |
20,176,849 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01328:Dsc2
|
APN |
18 |
20,181,343 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL01338:Dsc2
|
APN |
18 |
20,180,214 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL01727:Dsc2
|
APN |
18 |
20,171,257 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01766:Dsc2
|
APN |
18 |
20,179,399 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL02228:Dsc2
|
APN |
18 |
20,176,790 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02560:Dsc2
|
APN |
18 |
20,178,596 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02794:Dsc2
|
APN |
18 |
20,174,788 (GRCm39) |
missense |
probably damaging |
1.00 |
|
3-1:Dsc2
|
UTSW |
18 |
20,180,136 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
PIT4305001:Dsc2
|
UTSW |
18 |
20,179,300 (GRCm39) |
missense |
probably damaging |
0.96 |
|
PIT4431001:Dsc2
|
UTSW |
18 |
20,179,334 (GRCm39) |
nonsense |
probably null |
|
|
R0288:Dsc2
|
UTSW |
18 |
20,166,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Dsc2
|
UTSW |
18 |
20,184,283 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0562:Dsc2
|
UTSW |
18 |
20,174,594 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0697:Dsc2
|
UTSW |
18 |
20,174,509 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0940:Dsc2
|
UTSW |
18 |
20,183,116 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1081:Dsc2
|
UTSW |
18 |
20,166,352 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1140:Dsc2
|
UTSW |
18 |
20,165,269 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1515:Dsc2
|
UTSW |
18 |
20,178,622 (GRCm39) |
missense |
probably benign |
0.40 |
|
R1515:Dsc2
|
UTSW |
18 |
20,167,758 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1558:Dsc2
|
UTSW |
18 |
20,183,208 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1654:Dsc2
|
UTSW |
18 |
20,179,303 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2061:Dsc2
|
UTSW |
18 |
20,165,456 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R2089:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2091:Dsc2
|
UTSW |
18 |
20,166,351 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R2172:Dsc2
|
UTSW |
18 |
20,178,559 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2247:Dsc2
|
UTSW |
18 |
20,168,369 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2472:Dsc2
|
UTSW |
18 |
20,178,526 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2927:Dsc2
|
UTSW |
18 |
20,178,558 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3611:Dsc2
|
UTSW |
18 |
20,165,408 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3961:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R3963:Dsc2
|
UTSW |
18 |
20,184,284 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4353:Dsc2
|
UTSW |
18 |
20,183,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4362:Dsc2
|
UTSW |
18 |
20,183,214 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4612:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4613:Dsc2
|
UTSW |
18 |
20,174,876 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4752:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5056:Dsc2
|
UTSW |
18 |
20,183,199 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5267:Dsc2
|
UTSW |
18 |
20,167,640 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5445:Dsc2
|
UTSW |
18 |
20,168,360 (GRCm39) |
missense |
possibly damaging |
0.76 |
|
R5507:Dsc2
|
UTSW |
18 |
20,179,336 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5575:Dsc2
|
UTSW |
18 |
20,168,447 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5781:Dsc2
|
UTSW |
18 |
20,165,567 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6102:Dsc2
|
UTSW |
18 |
20,180,165 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6129:Dsc2
|
UTSW |
18 |
20,178,487 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6362:Dsc2
|
UTSW |
18 |
20,168,520 (GRCm39) |
nonsense |
probably null |
|
|
R6433:Dsc2
|
UTSW |
18 |
20,184,232 (GRCm39) |
critical splice donor site |
probably null |
|
|
R6513:Dsc2
|
UTSW |
18 |
20,179,295 (GRCm39) |
missense |
probably benign |
|
|
R6615:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6619:Dsc2
|
UTSW |
18 |
20,165,335 (GRCm39) |
missense |
probably benign |
0.22 |
|
R6665:Dsc2
|
UTSW |
18 |
20,183,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6961:Dsc2
|
UTSW |
18 |
20,171,279 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7179:Dsc2
|
UTSW |
18 |
20,168,332 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7275:Dsc2
|
UTSW |
18 |
20,184,236 (GRCm39) |
nonsense |
probably null |
|
|
R7352:Dsc2
|
UTSW |
18 |
20,168,392 (GRCm39) |
missense |
probably benign |
0.39 |
|
R7386:Dsc2
|
UTSW |
18 |
20,174,983 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R7496:Dsc2
|
UTSW |
18 |
20,168,451 (GRCm39) |
nonsense |
probably null |
|
|
R7510:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R7580:Dsc2
|
UTSW |
18 |
20,183,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7718:Dsc2
|
UTSW |
18 |
20,174,835 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,373 (GRCm39) |
missense |
probably benign |
0.16 |
|
R7733:Dsc2
|
UTSW |
18 |
20,181,372 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7818:Dsc2
|
UTSW |
18 |
20,183,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7852:Dsc2
|
UTSW |
18 |
20,179,342 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R7998:Dsc2
|
UTSW |
18 |
20,167,720 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R8029:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8030:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8031:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8032:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8059:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8060:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8061:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8062:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8063:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8082:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8090:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8114:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8115:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8116:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8117:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8118:Dsc2
|
UTSW |
18 |
20,165,331 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R8328:Dsc2
|
UTSW |
18 |
20,165,576 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8545:Dsc2
|
UTSW |
18 |
20,167,722 (GRCm39) |
nonsense |
probably null |
|
|
R9005:Dsc2
|
UTSW |
18 |
20,171,151 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9017:Dsc2
|
UTSW |
18 |
20,176,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9111:Dsc2
|
UTSW |
18 |
20,167,764 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9396:Dsc2
|
UTSW |
18 |
20,174,773 (GRCm39) |
nonsense |
probably null |
|
|
R9487:Dsc2
|
UTSW |
18 |
20,180,276 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9663:Dsc2
|
UTSW |
18 |
20,171,205 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Dsc2
|
UTSW |
18 |
20,179,361 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1176:Dsc2
|
UTSW |
18 |
20,168,356 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCAGTTAGCCCTAAAGAAACAC -3'
(R):5'- TCACATGCCTTTATTTCAGGACAC -3'
Sequencing Primer
(F):5'- AATTACACTCCATGCATATCATCTC -3'
(R):5'- CATGCCTTTATTTCAGGACACATATC -3'
|
| Posted On |
2016-04-27 |
Incidental Mutation