Incidental Mutation 'R4981:Epha3'
| ID |
384870 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Epha3
|
| Ensembl Gene |
ENSMUSG00000052504 |
| Gene Name |
Eph receptor A3 |
| Synonyms |
End3, Tyro4, Cek4, Hek, Hek4, Mek4 |
| MMRRC Submission |
042576-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.225)
|
| Stock # |
R4981 (G1)
|
| Quality Score |
144 |
|
Status
|
Validated
|
| Chromosome |
16 |
| Chromosomal Location |
63363897-63684538 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 63472775 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Aspartic acid
at position 370
(V370D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000155997
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000064405]
[ENSMUST00000232049]
[ENSMUST00000232461]
[ENSMUST00000232654]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000064405
AA Change: V370D
PolyPhen 2
Score 0.011 (Sensitivity: 0.96; Specificity: 0.78)
|
| SMART Domains |
Protein: ENSMUSP00000066554
Gene: ENSMUSG00000052504
AA Change: V370D
| Domain | Start | End | E-Value | Type |
|---|
|
signal peptide
|
1 |
20 |
N/A |
INTRINSIC |
|
EPH_lbd
|
29 |
202 |
1.76e-127 |
SMART |
|
Pfam:GCC2_GCC3
|
263 |
306 |
6.6e-9 |
PFAM |
|
FN3
|
326 |
418 |
1.14e-5 |
SMART |
|
FN3
|
437 |
518 |
4.8e-13 |
SMART |
|
Pfam:EphA2_TM
|
543 |
619 |
8.2e-25 |
PFAM |
|
TyrKc
|
622 |
879 |
5.16e-140 |
SMART |
|
SAM
|
909 |
976 |
1.08e-13 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000232049
AA Change: V370D
PolyPhen 2
Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000232461
AA Change: V69D
PolyPhen 2
Score 0.011 (Sensitivity: 0.96; Specificity: 0.78)
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000232654
AA Change: V370D
PolyPhen 2
Score 0.042 (Sensitivity: 0.94; Specificity: 0.83)
|
| Meta Mutation Damage Score |
0.0898 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.2%
- 10x: 96.0%
- 20x: 91.3%
|
| Validation Efficiency |
100% (105/105) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene belongs to the ephrin receptor subfamily of the protein-tyrosine kinase family. EPH and EPH-related receptors have been implicated in mediating developmental events, particularly in the nervous system. Receptors in the EPH subfamily typically have a single kinase domain and an extracellular region containing a Cys-rich domain and 2 fibronectin type III repeats. The ephrin receptors are divided into 2 groups based on the similarity of their extracellular domain sequences and their affinities for binding ephrin-A and ephrin-B ligands. This gene encodes a protein that binds ephrin-A ligands. Two alternatively spliced transcript variants have been described for this gene. [provided by RefSeq, Jul 2008]
PHENOTYPE: Mice homozygous for disruptions in this gene usually die within 48 hours of birth of cardiac failure. Survivors develop normally with no indications of cardiac abnormalities. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(3) : Targeted, knock-out(1) Gene trapped(2) |
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2700097O09Rik |
A |
T |
12: 55,095,772 (GRCm39) |
|
probably null |
Het |
| Aatf |
T |
C |
11: 84,402,323 (GRCm39) |
D121G |
probably benign |
Het |
| Amer2 |
T |
A |
14: 60,617,176 (GRCm39) |
L331H |
probably damaging |
Het |
| Ang4 |
T |
G |
14: 52,001,829 (GRCm39) |
K40Q |
probably benign |
Het |
| Aspm |
A |
C |
1: 139,398,498 (GRCm39) |
|
probably null |
Het |
| Cacna1c |
A |
T |
6: 118,728,432 (GRCm39) |
D337E |
probably benign |
Het |
| Ccdc124 |
T |
C |
8: 71,321,429 (GRCm39) |
E134G |
probably benign |
Het |
| Ccdc7a |
G |
T |
8: 129,711,464 (GRCm39) |
A312E |
probably benign |
Het |
| Cd209g |
A |
G |
8: 4,186,845 (GRCm39) |
D130G |
probably damaging |
Het |
| Cd320 |
T |
C |
17: 34,066,549 (GRCm39) |
S96P |
probably benign |
Het |
| Cenatac |
A |
T |
9: 44,329,245 (GRCm39) |
F14Y |
probably damaging |
Het |
| Clu |
C |
G |
14: 66,210,815 (GRCm39) |
Q134E |
probably damaging |
Het |
| Cnksr3 |
T |
A |
10: 7,110,777 (GRCm39) |
H28L |
probably benign |
Het |
| Cntnap1 |
T |
C |
11: 101,067,159 (GRCm39) |
|
probably null |
Het |
| Col22a1 |
C |
T |
15: 71,732,915 (GRCm39) |
C546Y |
unknown |
Het |
| Col6a3 |
C |
T |
1: 90,706,565 (GRCm39) |
V2183I |
unknown |
Het |
| Cop1 |
A |
G |
1: 159,152,638 (GRCm39) |
|
probably benign |
Het |
| Cpne8 |
T |
C |
15: 90,563,438 (GRCm39) |
I24V |
probably benign |
Het |
| Cspp1 |
T |
A |
1: 10,196,688 (GRCm39) |
N900K |
probably damaging |
Het |
| Dennd5b |
G |
A |
6: 148,911,270 (GRCm39) |
L978F |
possibly damaging |
Het |
| Depdc1a |
G |
T |
3: 159,229,550 (GRCm39) |
M627I |
probably benign |
Het |
| Dnah3 |
A |
T |
7: 119,555,424 (GRCm39) |
N2721K |
probably benign |
Het |
| Dnase1l1 |
C |
T |
X: 73,320,644 (GRCm39) |
|
probably null |
Homo |
| Dsg1b |
A |
G |
18: 20,541,925 (GRCm39) |
T811A |
possibly damaging |
Het |
| Emilin1 |
C |
G |
5: 31,076,695 (GRCm39) |
Q847E |
probably benign |
Het |
| Epha5 |
T |
A |
5: 84,298,342 (GRCm39) |
T406S |
probably damaging |
Het |
| Ephb1 |
A |
T |
9: 101,918,159 (GRCm39) |
I450N |
probably benign |
Het |
| Ephb2 |
A |
G |
4: 136,423,321 (GRCm39) |
M319T |
probably benign |
Het |
| Eps15l1 |
A |
G |
8: 73,132,833 (GRCm39) |
|
probably null |
Het |
| Fbxo9 |
G |
A |
9: 77,993,168 (GRCm39) |
|
probably benign |
Het |
| Fgd5 |
T |
C |
6: 91,966,281 (GRCm39) |
I838T |
probably damaging |
Het |
| Fnbp4 |
T |
C |
2: 90,596,174 (GRCm39) |
F582L |
probably damaging |
Het |
| Frs3 |
T |
C |
17: 48,000,187 (GRCm39) |
|
probably null |
Het |
| Fscb |
C |
T |
12: 64,520,393 (GRCm39) |
V358I |
possibly damaging |
Het |
| Fus |
G |
T |
7: 127,566,727 (GRCm39) |
|
probably benign |
Het |
| Fyb1 |
CCTCTCTCTCTCTCTCTCTCT |
CCTCTCTCTCTCTCTCTCT |
15: 6,676,092 (GRCm39) |
|
probably benign |
Het |
| Glra3 |
A |
T |
8: 56,444,270 (GRCm39) |
I77F |
possibly damaging |
Het |
| Gm4454 |
C |
T |
7: 38,269,860 (GRCm39) |
|
noncoding transcript |
Het |
| Gng3 |
G |
A |
19: 8,815,625 (GRCm39) |
A37V |
possibly damaging |
Het |
| Grin3b |
T |
A |
10: 79,812,191 (GRCm39) |
|
probably benign |
Het |
| Herpud1 |
A |
G |
8: 95,118,422 (GRCm39) |
Y41C |
probably damaging |
Het |
| Igkv4-92 |
G |
C |
6: 68,732,028 (GRCm39) |
S115R |
possibly damaging |
Het |
| Ikbip |
T |
A |
10: 90,931,848 (GRCm39) |
I164N |
probably benign |
Het |
| Kank1 |
A |
G |
19: 25,388,759 (GRCm39) |
T783A |
probably benign |
Het |
| Kcnq3 |
A |
T |
15: 65,903,254 (GRCm39) |
V152E |
possibly damaging |
Het |
| Kif23 |
C |
T |
9: 61,839,153 (GRCm39) |
R314H |
probably damaging |
Het |
| Klc4 |
T |
C |
17: 46,955,287 (GRCm39) |
H49R |
probably benign |
Het |
| Klhl20 |
A |
T |
1: 160,930,575 (GRCm39) |
I309N |
possibly damaging |
Het |
| Lgals4 |
A |
G |
7: 28,540,701 (GRCm39) |
Y268C |
probably damaging |
Het |
| Lingo4 |
A |
G |
3: 94,306,761 (GRCm39) |
Q13R |
probably benign |
Het |
| Lmtk2 |
C |
A |
5: 144,113,265 (GRCm39) |
F1328L |
probably damaging |
Het |
| Mapk14 |
A |
G |
17: 28,960,765 (GRCm39) |
R179G |
probably damaging |
Het |
| Mbd3l1 |
A |
T |
9: 18,396,201 (GRCm39) |
T109S |
probably benign |
Het |
| Megf6 |
T |
C |
4: 154,351,907 (GRCm39) |
F1169L |
possibly damaging |
Het |
| Mrgpra1 |
A |
T |
7: 46,984,959 (GRCm39) |
V240D |
probably damaging |
Het |
| Muc6 |
G |
A |
7: 141,218,313 (GRCm39) |
S2120F |
possibly damaging |
Het |
| Myh1 |
T |
C |
11: 67,115,300 (GRCm39) |
|
probably benign |
Het |
| Nav3 |
T |
C |
10: 109,716,553 (GRCm39) |
I172V |
probably benign |
Het |
| Nemp1 |
T |
A |
10: 127,529,399 (GRCm39) |
L178Q |
probably damaging |
Het |
| Numa1 |
T |
C |
7: 101,641,881 (GRCm39) |
S110P |
probably damaging |
Het |
| Or4a75 |
A |
G |
2: 89,447,769 (GRCm39) |
Y256H |
probably damaging |
Het |
| Or4c117 |
T |
C |
2: 88,955,845 (GRCm39) |
T77A |
probably benign |
Het |
| Or51k1 |
A |
G |
7: 103,661,312 (GRCm39) |
I199T |
probably damaging |
Het |
| Or5ak25 |
A |
G |
2: 85,268,813 (GRCm39) |
S230P |
probably damaging |
Het |
| Or8k30 |
T |
C |
2: 86,339,171 (GRCm39) |
Y123H |
probably damaging |
Het |
| Or9q1 |
A |
T |
19: 13,805,458 (GRCm39) |
F101I |
probably damaging |
Het |
| Pard3b |
T |
G |
1: 62,383,219 (GRCm39) |
M771R |
probably damaging |
Het |
| Phkg2 |
A |
G |
7: 127,181,551 (GRCm39) |
I245V |
probably damaging |
Het |
| Pik3cg |
A |
T |
12: 32,254,103 (GRCm39) |
M628K |
possibly damaging |
Het |
| Poln |
A |
G |
5: 34,264,429 (GRCm39) |
|
probably null |
Het |
| Ppip5k1 |
A |
T |
2: 121,142,871 (GRCm39) |
S1172T |
probably damaging |
Het |
| Prdm5 |
A |
T |
6: 65,847,446 (GRCm39) |
H363L |
probably damaging |
Het |
| Prkdc |
A |
G |
16: 15,496,173 (GRCm39) |
Y788C |
probably damaging |
Het |
| Prrc2c |
T |
A |
1: 162,520,116 (GRCm39) |
R2076S |
probably damaging |
Het |
| Sh2d2a |
A |
G |
3: 87,756,728 (GRCm39) |
Y191C |
probably damaging |
Het |
| Slc20a1 |
T |
C |
2: 129,041,919 (GRCm39) |
I94T |
probably damaging |
Het |
| Sptbn2 |
T |
C |
19: 4,801,686 (GRCm39) |
V2366A |
probably benign |
Het |
| Stab2 |
T |
A |
10: 86,796,087 (GRCm39) |
M387L |
probably benign |
Het |
| Syne2 |
T |
G |
12: 75,987,993 (GRCm39) |
M1718R |
probably damaging |
Het |
| Synm |
G |
T |
7: 67,384,235 (GRCm39) |
F700L |
probably benign |
Het |
| Tmco4 |
T |
C |
4: 138,718,012 (GRCm39) |
F51L |
possibly damaging |
Het |
| Tmem104 |
C |
A |
11: 115,095,962 (GRCm39) |
P168T |
probably damaging |
Het |
| Tril |
G |
T |
6: 53,795,905 (GRCm39) |
T439K |
probably benign |
Het |
| Trim2 |
A |
G |
3: 84,085,042 (GRCm39) |
L559P |
probably damaging |
Het |
| Trim3 |
A |
G |
7: 105,268,335 (GRCm39) |
V149A |
probably damaging |
Het |
| Triml2 |
A |
G |
8: 43,640,717 (GRCm39) |
N191S |
probably benign |
Het |
| Usp4 |
A |
G |
9: 108,258,617 (GRCm39) |
D16G |
probably benign |
Het |
| Vmn2r58 |
G |
A |
7: 41,486,885 (GRCm39) |
T670I |
probably damaging |
Het |
| Vmn2r97 |
G |
T |
17: 19,160,436 (GRCm39) |
G524* |
probably null |
Het |
| Xpo5 |
C |
A |
17: 46,531,743 (GRCm39) |
F426L |
probably damaging |
Het |
| Zfp800 |
A |
G |
6: 28,247,190 (GRCm39) |
L84S |
probably damaging |
Het |
| Zranb2 |
T |
G |
3: 157,252,378 (GRCm39) |
|
probably benign |
Het |
| Zswim4 |
C |
T |
8: 84,953,296 (GRCm39) |
|
probably null |
Het |
|
| Other mutations in Epha3 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00773:Epha3
|
APN |
16 |
63,387,047 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01358:Epha3
|
APN |
16 |
63,416,109 (GRCm39) |
splice site |
probably benign |
|
|
IGL01713:Epha3
|
APN |
16 |
63,372,925 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02371:Epha3
|
APN |
16 |
63,405,383 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
IGL03111:Epha3
|
APN |
16 |
63,473,809 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL03208:Epha3
|
APN |
16 |
63,431,452 (GRCm39) |
missense |
probably damaging |
1.00 |
|
laterality
|
UTSW |
16 |
63,388,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
midline
|
UTSW |
16 |
63,664,507 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
stride
|
UTSW |
16 |
63,372,857 (GRCm39) |
missense |
probably benign |
0.00 |
|
F2404:Epha3
|
UTSW |
16 |
63,366,531 (GRCm39) |
missense |
probably benign |
0.14 |
|
P0041:Epha3
|
UTSW |
16 |
63,433,231 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4498001:Epha3
|
UTSW |
16 |
63,372,889 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4585001:Epha3
|
UTSW |
16 |
63,386,940 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0147:Epha3
|
UTSW |
16 |
63,433,307 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0148:Epha3
|
UTSW |
16 |
63,433,307 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R0336:Epha3
|
UTSW |
16 |
63,387,011 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0738:Epha3
|
UTSW |
16 |
63,415,975 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0833:Epha3
|
UTSW |
16 |
63,423,882 (GRCm39) |
splice site |
probably benign |
|
|
R0836:Epha3
|
UTSW |
16 |
63,423,882 (GRCm39) |
splice site |
probably benign |
|
|
R0969:Epha3
|
UTSW |
16 |
63,386,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1160:Epha3
|
UTSW |
16 |
63,593,431 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1205:Epha3
|
UTSW |
16 |
63,418,611 (GRCm39) |
frame shift |
probably null |
|
|
R1349:Epha3
|
UTSW |
16 |
63,431,416 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1372:Epha3
|
UTSW |
16 |
63,431,416 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1469:Epha3
|
UTSW |
16 |
63,473,857 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1469:Epha3
|
UTSW |
16 |
63,473,857 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R1500:Epha3
|
UTSW |
16 |
63,416,025 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1523:Epha3
|
UTSW |
16 |
63,431,311 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1532:Epha3
|
UTSW |
16 |
63,366,541 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1544:Epha3
|
UTSW |
16 |
63,593,416 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1681:Epha3
|
UTSW |
16 |
63,416,091 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1708:Epha3
|
UTSW |
16 |
63,403,870 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1803:Epha3
|
UTSW |
16 |
63,422,651 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1893:Epha3
|
UTSW |
16 |
63,388,762 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1957:Epha3
|
UTSW |
16 |
63,593,315 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2144:Epha3
|
UTSW |
16 |
63,593,680 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R2190:Epha3
|
UTSW |
16 |
63,366,552 (GRCm39) |
missense |
probably benign |
0.05 |
|
R2198:Epha3
|
UTSW |
16 |
63,664,507 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R2344:Epha3
|
UTSW |
16 |
63,472,746 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R2504:Epha3
|
UTSW |
16 |
63,423,988 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R2911:Epha3
|
UTSW |
16 |
63,472,775 (GRCm39) |
missense |
probably benign |
|
|
R3889:Epha3
|
UTSW |
16 |
63,431,327 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4223:Epha3
|
UTSW |
16 |
63,403,902 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4836:Epha3
|
UTSW |
16 |
63,403,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5044:Epha3
|
UTSW |
16 |
63,422,650 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
R5195:Epha3
|
UTSW |
16 |
63,366,510 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5248:Epha3
|
UTSW |
16 |
63,418,620 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5478:Epha3
|
UTSW |
16 |
63,403,896 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6052:Epha3
|
UTSW |
16 |
63,423,967 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R6167:Epha3
|
UTSW |
16 |
63,433,287 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6337:Epha3
|
UTSW |
16 |
63,388,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6342:Epha3
|
UTSW |
16 |
63,403,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6793:Epha3
|
UTSW |
16 |
63,593,818 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6908:Epha3
|
UTSW |
16 |
63,418,612 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7029:Epha3
|
UTSW |
16 |
63,593,698 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7059:Epha3
|
UTSW |
16 |
63,388,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7175:Epha3
|
UTSW |
16 |
63,403,863 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7204:Epha3
|
UTSW |
16 |
63,472,695 (GRCm39) |
missense |
probably benign |
|
|
R7217:Epha3
|
UTSW |
16 |
63,372,857 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7315:Epha3
|
UTSW |
16 |
63,372,972 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7389:Epha3
|
UTSW |
16 |
63,593,347 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7419:Epha3
|
UTSW |
16 |
63,418,657 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7572:Epha3
|
UTSW |
16 |
63,431,443 (GRCm39) |
nonsense |
probably null |
|
|
R7667:Epha3
|
UTSW |
16 |
63,386,963 (GRCm39) |
missense |
probably benign |
0.21 |
|
R7686:Epha3
|
UTSW |
16 |
63,593,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7855:Epha3
|
UTSW |
16 |
63,593,923 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8085:Epha3
|
UTSW |
16 |
63,403,873 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8167:Epha3
|
UTSW |
16 |
63,388,804 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8260:Epha3
|
UTSW |
16 |
63,403,917 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8290:Epha3
|
UTSW |
16 |
63,472,859 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8298:Epha3
|
UTSW |
16 |
63,386,961 (GRCm39) |
missense |
probably benign |
0.16 |
|
R8350:Epha3
|
UTSW |
16 |
63,472,853 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8450:Epha3
|
UTSW |
16 |
63,472,853 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R8470:Epha3
|
UTSW |
16 |
63,664,510 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8478:Epha3
|
UTSW |
16 |
63,593,444 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8724:Epha3
|
UTSW |
16 |
63,403,818 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8862:Epha3
|
UTSW |
16 |
63,431,348 (GRCm39) |
missense |
probably benign |
|
|
R8921:Epha3
|
UTSW |
16 |
63,472,838 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R9519:Epha3
|
UTSW |
16 |
63,472,668 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R9563:Epha3
|
UTSW |
16 |
63,366,510 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R9795:Epha3
|
UTSW |
16 |
63,372,910 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1176:Epha3
|
UTSW |
16 |
63,405,375 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- GCTGCCAATGTGTACTCACC -3'
(R):5'- CAACTGGAAGTGATGCTCATTAATC -3'
Sequencing Primer
(F):5'- CAATGTGTACTCACCAGCCTGATTAG -3'
(R):5'- CTTTGTGGAACTACTTTGCAGGACC -3'
|
| Posted On |
2016-05-10 |
Incidental Mutation