Incidental Mutation 'R4997:Prrc2b'
| ID |
385312 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Prrc2b
|
| Ensembl Gene |
ENSMUSG00000039262 |
| Gene Name |
proline-rich coiled-coil 2B |
| Synonyms |
5830434P21Rik, Bat2l |
| MMRRC Submission |
042591-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R4997 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
2 |
| Chromosomal Location |
32041094-32124549 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 32112323 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Tyrosine to Cysteine
at position 1929
(Y1929C)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000064892
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000036691]
[ENSMUST00000069817]
|
| AlphaFold |
Q7TPM1 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000036691
AA Change: Y1243C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000035734
Gene: ENSMUSG00000039262
AA Change: Y1243C
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
194 |
2.7e-85 |
PFAM |
|
low complexity region
|
359 |
374 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
394 |
N/A |
INTRINSIC |
|
low complexity region
|
413 |
424 |
N/A |
INTRINSIC |
|
coiled coil region
|
494 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
621 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
656 |
N/A |
INTRINSIC |
|
low complexity region
|
885 |
900 |
N/A |
INTRINSIC |
|
low complexity region
|
992 |
1007 |
N/A |
INTRINSIC |
|
low complexity region
|
1112 |
1126 |
N/A |
INTRINSIC |
|
low complexity region
|
1218 |
1233 |
N/A |
INTRINSIC |
|
low complexity region
|
1257 |
1275 |
N/A |
INTRINSIC |
|
low complexity region
|
1402 |
1421 |
N/A |
INTRINSIC |
|
low complexity region
|
1425 |
1437 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000069817
AA Change: Y1929C
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000064892
Gene: ENSMUSG00000039262
AA Change: Y1929C
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
191 |
3.1e-65 |
PFAM |
|
low complexity region
|
359 |
374 |
N/A |
INTRINSIC |
|
low complexity region
|
388 |
394 |
N/A |
INTRINSIC |
|
low complexity region
|
413 |
424 |
N/A |
INTRINSIC |
|
coiled coil region
|
494 |
544 |
N/A |
INTRINSIC |
|
low complexity region
|
600 |
621 |
N/A |
INTRINSIC |
|
low complexity region
|
638 |
656 |
N/A |
INTRINSIC |
|
low complexity region
|
960 |
977 |
N/A |
INTRINSIC |
|
low complexity region
|
1004 |
1018 |
N/A |
INTRINSIC |
|
low complexity region
|
1070 |
1094 |
N/A |
INTRINSIC |
|
low complexity region
|
1307 |
1325 |
N/A |
INTRINSIC |
|
low complexity region
|
1388 |
1401 |
N/A |
INTRINSIC |
|
low complexity region
|
1413 |
1426 |
N/A |
INTRINSIC |
|
low complexity region
|
1572 |
1587 |
N/A |
INTRINSIC |
|
low complexity region
|
1678 |
1693 |
N/A |
INTRINSIC |
|
low complexity region
|
1798 |
1812 |
N/A |
INTRINSIC |
|
low complexity region
|
1904 |
1919 |
N/A |
INTRINSIC |
|
low complexity region
|
1943 |
1961 |
N/A |
INTRINSIC |
|
low complexity region
|
2088 |
2107 |
N/A |
INTRINSIC |
|
low complexity region
|
2111 |
2123 |
N/A |
INTRINSIC |
|
low complexity region
|
2161 |
2174 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000083112
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000123270
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000128936
|
| SMART Domains |
Protein: ENSMUSP00000121664
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
53 |
68 |
N/A |
INTRINSIC |
|
low complexity region
|
159 |
174 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000129626
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000132459
AA Change: Y1170C
|
| SMART Domains |
Protein: ENSMUSP00000116429
Gene: ENSMUSG00000039262
AA Change: Y1170C
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:BAT2_N
|
1 |
119 |
9.8e-24 |
PFAM |
|
low complexity region
|
287 |
302 |
N/A |
INTRINSIC |
|
low complexity region
|
316 |
322 |
N/A |
INTRINSIC |
|
low complexity region
|
341 |
352 |
N/A |
INTRINSIC |
|
coiled coil region
|
421 |
471 |
N/A |
INTRINSIC |
|
low complexity region
|
528 |
549 |
N/A |
INTRINSIC |
|
low complexity region
|
566 |
584 |
N/A |
INTRINSIC |
|
low complexity region
|
813 |
828 |
N/A |
INTRINSIC |
|
low complexity region
|
920 |
935 |
N/A |
INTRINSIC |
|
low complexity region
|
1040 |
1054 |
N/A |
INTRINSIC |
|
low complexity region
|
1146 |
1161 |
N/A |
INTRINSIC |
|
low complexity region
|
1185 |
1203 |
N/A |
INTRINSIC |
|
low complexity region
|
1330 |
1349 |
N/A |
INTRINSIC |
|
low complexity region
|
1353 |
1365 |
N/A |
INTRINSIC |
|
low complexity region
|
1403 |
1416 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000175128
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000140015
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000141053
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000142219
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000156313
|
| SMART Domains |
Protein: ENSMUSP00000114994
Gene: ENSMUSG00000039262
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
125 |
140 |
N/A |
INTRINSIC |
|
low complexity region
|
231 |
246 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.1%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A630023A22Rik |
A |
T |
14: 33,775,623 (GRCm39) |
M1L |
probably benign |
Het |
| Abca7 |
C |
A |
10: 79,843,154 (GRCm39) |
Q1210K |
possibly damaging |
Het |
| Abcc4 |
C |
T |
14: 118,753,915 (GRCm39) |
W1024* |
probably null |
Het |
| Accs |
A |
T |
2: 93,672,228 (GRCm39) |
Y213* |
probably null |
Het |
| Adam6a |
G |
T |
12: 113,508,991 (GRCm39) |
G455C |
probably damaging |
Het |
| Adcy1 |
A |
C |
11: 7,111,298 (GRCm39) |
Y863S |
probably benign |
Het |
| Adgrg1 |
A |
G |
8: 95,736,148 (GRCm39) |
D434G |
probably damaging |
Het |
| Afap1l1 |
C |
T |
18: 61,884,879 (GRCm39) |
R202Q |
probably benign |
Het |
| Aldh3a1 |
T |
C |
11: 61,103,137 (GRCm39) |
V27A |
probably benign |
Het |
| Antxr2 |
A |
G |
5: 98,125,553 (GRCm39) |
F235L |
probably benign |
Het |
| Arhgap23 |
T |
A |
11: 97,342,846 (GRCm39) |
V376E |
probably damaging |
Het |
| Brca1 |
A |
C |
11: 101,415,159 (GRCm39) |
S992A |
probably damaging |
Het |
| Brcc3dc |
A |
G |
10: 108,535,649 (GRCm39) |
I102T |
probably benign |
Het |
| Calcrl |
A |
T |
2: 84,181,592 (GRCm39) |
C185* |
probably null |
Het |
| Cep152 |
T |
C |
2: 125,428,271 (GRCm39) |
T787A |
probably benign |
Het |
| Coch |
T |
A |
12: 51,649,964 (GRCm39) |
|
probably null |
Het |
| Col5a1 |
T |
A |
2: 27,922,794 (GRCm39) |
Y287* |
probably null |
Het |
| Dis3l |
A |
G |
9: 64,219,224 (GRCm39) |
S569P |
possibly damaging |
Het |
| Dnai1 |
A |
G |
4: 41,597,919 (GRCm39) |
I74V |
possibly damaging |
Het |
| Dpy19l4 |
A |
G |
4: 11,287,493 (GRCm39) |
V394A |
probably benign |
Het |
| Egfem1 |
A |
G |
3: 29,207,739 (GRCm39) |
H122R |
probably benign |
Het |
| Endou |
A |
G |
15: 97,617,458 (GRCm39) |
L164P |
probably damaging |
Het |
| Epgn |
A |
G |
5: 91,180,098 (GRCm39) |
E80G |
possibly damaging |
Het |
| Fcgbpl1 |
T |
G |
7: 27,843,349 (GRCm39) |
S746A |
possibly damaging |
Het |
| Fitm1 |
T |
C |
14: 55,814,364 (GRCm39) |
S287P |
probably benign |
Het |
| Foxm1 |
A |
G |
6: 128,342,731 (GRCm39) |
N22D |
probably benign |
Het |
| Gsdmc |
A |
T |
15: 63,648,629 (GRCm39) |
M426K |
probably damaging |
Het |
| Hmcn2 |
T |
A |
2: 31,291,720 (GRCm39) |
V2418D |
probably damaging |
Het |
| Hs3st2 |
T |
A |
7: 121,099,679 (GRCm39) |
L175Q |
possibly damaging |
Het |
| Il1r2 |
T |
C |
1: 40,160,206 (GRCm39) |
|
probably null |
Het |
| Il27ra |
A |
T |
8: 84,766,156 (GRCm39) |
Y209* |
probably null |
Het |
| Inpp5a |
A |
T |
7: 138,980,654 (GRCm39) |
S31C |
probably benign |
Het |
| Invs |
A |
G |
4: 48,396,332 (GRCm39) |
D335G |
probably damaging |
Het |
| Isg15 |
C |
T |
4: 156,284,154 (GRCm39) |
E125K |
possibly damaging |
Het |
| Klk14 |
G |
A |
7: 43,341,501 (GRCm39) |
C51Y |
probably damaging |
Het |
| Lama4 |
C |
A |
10: 38,968,262 (GRCm39) |
T1468K |
probably damaging |
Het |
| Lce1a2 |
A |
G |
3: 92,576,395 (GRCm39) |
S56P |
unknown |
Het |
| Llgl1 |
C |
T |
11: 60,600,394 (GRCm39) |
P581L |
probably benign |
Het |
| Lmf1 |
G |
A |
17: 25,807,650 (GRCm39) |
W164* |
probably null |
Het |
| Mad2l1bp |
G |
T |
17: 46,463,804 (GRCm39) |
C73* |
probably null |
Het |
| Mpzl1 |
A |
C |
1: 165,429,350 (GRCm39) |
V230G |
probably damaging |
Het |
| Myo3b |
A |
G |
2: 70,088,427 (GRCm39) |
T869A |
possibly damaging |
Het |
| Ncor2 |
T |
C |
5: 125,111,074 (GRCm39) |
H1316R |
probably damaging |
Het |
| Nlrp1b |
T |
A |
11: 71,109,160 (GRCm39) |
I114F |
probably damaging |
Het |
| Nsun7 |
A |
G |
5: 66,453,182 (GRCm39) |
I632M |
probably benign |
Het |
| Nubp1 |
T |
C |
16: 10,239,185 (GRCm39) |
I234T |
probably benign |
Het |
| Olfml1 |
A |
G |
7: 107,170,413 (GRCm39) |
D100G |
probably damaging |
Het |
| Or1e1b-ps1 |
T |
A |
11: 73,845,612 (GRCm39) |
L32Q |
probably damaging |
Het |
| Or5p73 |
C |
A |
7: 108,064,701 (GRCm39) |
Q57K |
probably benign |
Het |
| Or7g23 |
A |
T |
9: 19,086,627 (GRCm39) |
L115Q |
probably damaging |
Het |
| Osmr |
G |
T |
15: 6,845,120 (GRCm39) |
P882Q |
probably benign |
Het |
| Peg10 |
TCAGGATCC |
TCAGGATCCCCAGCAGGATCC |
6: 4,756,457 (GRCm39) |
|
probably benign |
Het |
| Per2 |
T |
A |
1: 91,378,505 (GRCm39) |
T15S |
probably benign |
Het |
| Piezo2 |
A |
G |
18: 63,216,184 (GRCm39) |
Y1184H |
probably damaging |
Het |
| Pik3c2b |
C |
T |
1: 133,032,819 (GRCm39) |
A1560V |
probably damaging |
Het |
| Pik3cd |
A |
C |
4: 149,743,441 (GRCm39) |
L256R |
probably damaging |
Het |
| Ppl |
C |
A |
16: 4,907,235 (GRCm39) |
R1020L |
probably damaging |
Het |
| Ppp1r10 |
A |
G |
17: 36,234,976 (GRCm39) |
N60S |
probably damaging |
Het |
| Prkcg |
T |
C |
7: 3,371,097 (GRCm39) |
|
probably null |
Het |
| Prkci |
T |
C |
3: 31,085,375 (GRCm39) |
|
probably null |
Het |
| Prss12 |
T |
C |
3: 123,240,857 (GRCm39) |
V17A |
probably benign |
Het |
| Qtrt1 |
A |
G |
9: 21,328,654 (GRCm39) |
N206S |
probably benign |
Het |
| Rad54l2 |
A |
C |
9: 106,600,108 (GRCm39) |
S50A |
possibly damaging |
Het |
| Rhov |
C |
T |
2: 119,100,949 (GRCm39) |
R96H |
probably damaging |
Het |
| Rph3a |
A |
T |
5: 121,101,906 (GRCm39) |
V110E |
probably damaging |
Het |
| Rufy4 |
T |
C |
1: 74,186,822 (GRCm39) |
C537R |
probably damaging |
Het |
| Ryr2 |
A |
T |
13: 11,610,192 (GRCm39) |
N646K |
probably benign |
Het |
| Scn8a |
A |
G |
15: 100,854,935 (GRCm39) |
T141A |
probably damaging |
Het |
| Serping1 |
T |
C |
2: 84,600,629 (GRCm39) |
R238G |
possibly damaging |
Het |
| Shank3 |
T |
A |
15: 89,433,901 (GRCm39) |
W1474R |
probably damaging |
Het |
| Slc16a12 |
T |
A |
19: 34,652,358 (GRCm39) |
M263L |
probably benign |
Het |
| Spata13 |
T |
C |
14: 60,946,908 (GRCm39) |
V652A |
probably damaging |
Het |
| Spata31 |
G |
A |
13: 65,067,537 (GRCm39) |
M66I |
probably benign |
Het |
| Spem2 |
T |
C |
11: 69,708,558 (GRCm39) |
I136V |
probably benign |
Het |
| Supt5 |
T |
C |
7: 28,015,462 (GRCm39) |
H925R |
probably benign |
Het |
| Syk |
A |
T |
13: 52,766,484 (GRCm39) |
K190* |
probably null |
Het |
| Thsd1 |
T |
A |
8: 22,733,340 (GRCm39) |
V129D |
probably damaging |
Het |
| Tiprl |
A |
G |
1: 165,047,759 (GRCm39) |
V174A |
possibly damaging |
Het |
| Tmed4 |
T |
A |
11: 6,224,500 (GRCm39) |
|
probably null |
Het |
| Tnfrsf19 |
T |
C |
14: 61,208,658 (GRCm39) |
T288A |
probably benign |
Het |
| Tnfrsf25 |
T |
C |
4: 152,202,153 (GRCm39) |
|
probably null |
Het |
| Tpd52 |
A |
G |
3: 9,000,056 (GRCm39) |
L121S |
probably damaging |
Het |
| Trim30a |
T |
A |
7: 104,060,827 (GRCm39) |
K316N |
probably benign |
Het |
| Ttc3 |
T |
G |
16: 94,253,841 (GRCm39) |
D1221E |
probably damaging |
Het |
| Ttn |
C |
T |
2: 76,714,403 (GRCm39) |
|
probably benign |
Het |
| Ttn |
T |
C |
2: 76,776,615 (GRCm39) |
I1514V |
probably benign |
Het |
| Ulk2 |
T |
C |
11: 61,689,982 (GRCm39) |
T671A |
probably benign |
Het |
| Wasf1 |
C |
T |
10: 40,810,600 (GRCm39) |
P281S |
probably damaging |
Het |
| Wnt10b |
C |
A |
15: 98,672,084 (GRCm39) |
R211L |
probably damaging |
Het |
| Xpnpep3 |
T |
A |
15: 81,332,577 (GRCm39) |
C371* |
probably null |
Het |
| Zfp41 |
C |
T |
15: 75,490,617 (GRCm39) |
|
probably benign |
Het |
| Zfp553 |
T |
A |
7: 126,834,683 (GRCm39) |
N79K |
probably benign |
Het |
| Zmynd8 |
G |
T |
2: 165,634,736 (GRCm39) |
D1096E |
probably benign |
Het |
|
| Other mutations in Prrc2b |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00156:Prrc2b
|
APN |
2 |
32,098,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00846:Prrc2b
|
APN |
2 |
32,089,109 (GRCm39) |
splice site |
probably benign |
|
|
IGL00977:Prrc2b
|
APN |
2 |
32,103,822 (GRCm39) |
missense |
probably benign |
0.05 |
|
IGL01372:Prrc2b
|
APN |
2 |
32,113,942 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01993:Prrc2b
|
APN |
2 |
32,114,057 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
IGL02097:Prrc2b
|
APN |
2 |
32,081,513 (GRCm39) |
splice site |
probably benign |
|
|
IGL02165:Prrc2b
|
APN |
2 |
32,104,652 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02184:Prrc2b
|
APN |
2 |
32,111,467 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02238:Prrc2b
|
APN |
2 |
32,103,429 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02338:Prrc2b
|
APN |
2 |
32,104,047 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL02399:Prrc2b
|
APN |
2 |
32,116,973 (GRCm39) |
nonsense |
probably null |
|
|
IGL02597:Prrc2b
|
APN |
2 |
32,109,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02729:Prrc2b
|
APN |
2 |
32,098,770 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02743:Prrc2b
|
APN |
2 |
32,084,441 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02815:Prrc2b
|
APN |
2 |
32,094,265 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03159:Prrc2b
|
APN |
2 |
32,084,498 (GRCm39) |
missense |
probably damaging |
0.98 |
|
BB002:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB012:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
FR4304:Prrc2b
|
UTSW |
2 |
32,111,179 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0082:Prrc2b
|
UTSW |
2 |
32,102,310 (GRCm39) |
splice site |
probably benign |
|
|
R0105:Prrc2b
|
UTSW |
2 |
32,103,323 (GRCm39) |
nonsense |
probably null |
|
|
R0276:Prrc2b
|
UTSW |
2 |
32,109,666 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R0325:Prrc2b
|
UTSW |
2 |
32,089,103 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0436:Prrc2b
|
UTSW |
2 |
32,120,672 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0595:Prrc2b
|
UTSW |
2 |
32,073,189 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0607:Prrc2b
|
UTSW |
2 |
32,103,882 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0650:Prrc2b
|
UTSW |
2 |
32,119,267 (GRCm39) |
splice site |
probably benign |
|
|
R1282:Prrc2b
|
UTSW |
2 |
32,113,456 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1421:Prrc2b
|
UTSW |
2 |
32,090,990 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
R1452:Prrc2b
|
UTSW |
2 |
32,084,997 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1535:Prrc2b
|
UTSW |
2 |
32,094,301 (GRCm39) |
missense |
probably benign |
0.06 |
|
R1709:Prrc2b
|
UTSW |
2 |
32,084,473 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1710:Prrc2b
|
UTSW |
2 |
32,102,234 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2094:Prrc2b
|
UTSW |
2 |
32,072,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2202:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2203:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2204:Prrc2b
|
UTSW |
2 |
32,113,476 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2428:Prrc2b
|
UTSW |
2 |
32,106,067 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2435:Prrc2b
|
UTSW |
2 |
32,109,741 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R3439:Prrc2b
|
UTSW |
2 |
32,096,359 (GRCm39) |
missense |
probably benign |
0.01 |
|
R4175:Prrc2b
|
UTSW |
2 |
32,108,820 (GRCm39) |
intron |
probably benign |
|
|
R4710:Prrc2b
|
UTSW |
2 |
32,083,869 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R4728:Prrc2b
|
UTSW |
2 |
32,120,637 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4791:Prrc2b
|
UTSW |
2 |
32,107,351 (GRCm39) |
splice site |
probably null |
|
|
R4876:Prrc2b
|
UTSW |
2 |
32,104,212 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4908:Prrc2b
|
UTSW |
2 |
32,116,330 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R5240:Prrc2b
|
UTSW |
2 |
32,096,408 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5276:Prrc2b
|
UTSW |
2 |
32,104,734 (GRCm39) |
missense |
probably benign |
0.09 |
|
R5455:Prrc2b
|
UTSW |
2 |
32,111,355 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R5821:Prrc2b
|
UTSW |
2 |
32,102,144 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5835:Prrc2b
|
UTSW |
2 |
32,096,485 (GRCm39) |
missense |
probably benign |
0.18 |
|
R5958:Prrc2b
|
UTSW |
2 |
32,102,092 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R6052:Prrc2b
|
UTSW |
2 |
32,102,297 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R6218:Prrc2b
|
UTSW |
2 |
32,098,823 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6428:Prrc2b
|
UTSW |
2 |
32,116,508 (GRCm39) |
splice site |
probably null |
|
|
R6505:Prrc2b
|
UTSW |
2 |
32,112,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6812:Prrc2b
|
UTSW |
2 |
32,103,153 (GRCm39) |
missense |
probably benign |
0.30 |
|
R6826:Prrc2b
|
UTSW |
2 |
32,112,300 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R6827:Prrc2b
|
UTSW |
2 |
32,090,963 (GRCm39) |
missense |
probably benign |
0.37 |
|
R7021:Prrc2b
|
UTSW |
2 |
32,111,498 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7078:Prrc2b
|
UTSW |
2 |
32,103,531 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7081:Prrc2b
|
UTSW |
2 |
32,103,075 (GRCm39) |
missense |
probably benign |
0.12 |
|
R7101:Prrc2b
|
UTSW |
2 |
32,117,005 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R7215:Prrc2b
|
UTSW |
2 |
32,119,309 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7228:Prrc2b
|
UTSW |
2 |
32,104,318 (GRCm39) |
nonsense |
probably null |
|
|
R7566:Prrc2b
|
UTSW |
2 |
32,084,402 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7719:Prrc2b
|
UTSW |
2 |
32,107,280 (GRCm39) |
nonsense |
probably null |
|
|
R7925:Prrc2b
|
UTSW |
2 |
32,094,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7999:Prrc2b
|
UTSW |
2 |
32,084,426 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8099:Prrc2b
|
UTSW |
2 |
32,098,686 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8154:Prrc2b
|
UTSW |
2 |
32,108,689 (GRCm39) |
missense |
probably benign |
0.42 |
|
R8252:Prrc2b
|
UTSW |
2 |
32,109,392 (GRCm39) |
missense |
possibly damaging |
0.80 |
|
R8379:Prrc2b
|
UTSW |
2 |
32,104,666 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8485:Prrc2b
|
UTSW |
2 |
32,102,105 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8845:Prrc2b
|
UTSW |
2 |
32,106,162 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R8845:Prrc2b
|
UTSW |
2 |
32,102,105 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8919:Prrc2b
|
UTSW |
2 |
32,104,953 (GRCm39) |
missense |
probably benign |
|
|
R8982:Prrc2b
|
UTSW |
2 |
32,102,134 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9065:Prrc2b
|
UTSW |
2 |
32,109,304 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9127:Prrc2b
|
UTSW |
2 |
32,103,764 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9217:Prrc2b
|
UTSW |
2 |
32,103,414 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9338:Prrc2b
|
UTSW |
2 |
32,098,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9344:Prrc2b
|
UTSW |
2 |
32,103,600 (GRCm39) |
missense |
probably benign |
0.28 |
|
R9386:Prrc2b
|
UTSW |
2 |
32,104,125 (GRCm39) |
missense |
probably benign |
|
|
R9601:Prrc2b
|
UTSW |
2 |
32,090,953 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9607:Prrc2b
|
UTSW |
2 |
32,098,794 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9670:Prrc2b
|
UTSW |
2 |
32,103,199 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9706:Prrc2b
|
UTSW |
2 |
32,107,300 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1088:Prrc2b
|
UTSW |
2 |
32,106,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Prrc2b
|
UTSW |
2 |
32,104,441 (GRCm39) |
missense |
probably benign |
0.03 |
|
Z1177:Prrc2b
|
UTSW |
2 |
32,116,364 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- CTCTCTTCCATAGGAAACAGCC -3'
(R):5'- CACTCTCTGGGTATCACATGGG -3'
Sequencing Primer
(F):5'- TGCACCTGCCTGGGTTTC -3'
(R):5'- CTGGGTATCACATGGGGCAGG -3'
|
| Posted On |
2016-05-10 |
Incidental Mutation