Incidental Mutation 'R5093:Hfm1'
| ID |
387917 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Hfm1
|
| Ensembl Gene |
ENSMUSG00000043410 |
| Gene Name |
HFM1, ATP-dependent DNA helicase homolog |
| Synonyms |
LOC381663, A330009G12Rik, Mer3, Sec63d1 |
| MMRRC Submission |
042682-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.089)
|
| Stock # |
R5093 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
5 |
| Chromosomal Location |
106988058-107074187 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 107049597 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Serine to Threonine
at position 455
(S455T)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000112590
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000112690]
[ENSMUST00000117588]
[ENSMUST00000148686]
[ENSMUST00000200249]
|
| AlphaFold |
D3Z4R1 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000112690
AA Change: S455T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000108310
Gene: ENSMUSG00000043410
AA Change: S455T
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000117588
AA Change: S455T
PolyPhen 2
Score 1.000 (Sensitivity: 0.00; Specificity: 1.00)
|
| SMART Domains |
Protein: ENSMUSP00000112590
Gene: ENSMUSG00000043410
AA Change: S455T
| Domain | Start | End | E-Value | Type |
|---|
|
DEXDc
|
276 |
490 |
3.66e-29 |
SMART |
|
HELICc
|
571 |
657 |
1.56e-14 |
SMART |
|
low complexity region
|
751 |
764 |
N/A |
INTRINSIC |
|
Sec63
|
775 |
1090 |
5.66e-60 |
SMART |
|
Blast:Sec63
|
1130 |
1188 |
2e-18 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134292
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000137795
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000148686
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000200249
|
| SMART Domains |
Protein: ENSMUSP00000142727
Gene: ENSMUSG00000043410
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:ResIII
|
260 |
410 |
9.9e-7 |
PFAM |
|
Pfam:DEAD
|
281 |
410 |
1.5e-19 |
PFAM |
|
| Meta Mutation Damage Score |
0.5176 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.9%
- 20x: 94.1%
|
| Validation Efficiency |
99% (90/91) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The protein encoded by this gene is thought to be an ATP-dependent DNA helicase and is expressed mainly in germ-line cells. Defects in this gene are a cause of premature ovarian failure 9 (POF9). [provided by RefSeq, Apr 2014]
PHENOTYPE: Meiosis ais disrupted in homozygotes and bothe sexes are sterile [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 81 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4833420G17Rik |
C |
T |
13: 119,610,573 (GRCm39) |
|
probably benign |
Het |
| Abca9 |
A |
T |
11: 110,032,358 (GRCm39) |
L753Q |
probably damaging |
Het |
| Acvrl1 |
A |
G |
15: 101,032,628 (GRCm39) |
|
probably null |
Het |
| Adgrv1 |
A |
T |
13: 81,740,704 (GRCm39) |
N141K |
probably damaging |
Het |
| Aftph |
C |
T |
11: 20,659,619 (GRCm39) |
|
probably null |
Het |
| Aifm1 |
C |
T |
X: 47,571,637 (GRCm39) |
G371S |
probably benign |
Het |
| Aldh3b2 |
A |
G |
19: 4,029,433 (GRCm39) |
M269V |
probably benign |
Het |
| Ankrd44 |
T |
C |
1: 54,802,877 (GRCm39) |
Y207C |
probably damaging |
Het |
| Arhgap15 |
G |
T |
2: 44,212,767 (GRCm39) |
M412I |
probably damaging |
Het |
| Auts2 |
A |
C |
5: 131,468,296 (GRCm39) |
L783R |
probably damaging |
Het |
| Baiap2l1 |
A |
T |
5: 144,215,363 (GRCm39) |
Y381N |
probably damaging |
Het |
| Baiap3 |
T |
C |
17: 25,469,243 (GRCm39) |
D180G |
probably damaging |
Het |
| Cant1 |
T |
C |
11: 118,302,038 (GRCm39) |
Y93C |
probably damaging |
Het |
| Catsperg2 |
T |
C |
7: 29,416,423 (GRCm39) |
S330G |
probably benign |
Het |
| Ccdc73 |
A |
T |
2: 104,848,111 (GRCm39) |
|
probably benign |
Het |
| Cdc5l |
A |
T |
17: 45,703,967 (GRCm39) |
F752L |
possibly damaging |
Het |
| Celsr2 |
G |
T |
3: 108,320,689 (GRCm39) |
H708N |
possibly damaging |
Het |
| Cep170 |
T |
A |
1: 176,596,896 (GRCm39) |
K487M |
possibly damaging |
Het |
| Cerkl |
A |
T |
2: 79,163,867 (GRCm39) |
N66K |
probably damaging |
Het |
| Cilk1 |
G |
A |
9: 78,047,303 (GRCm39) |
V68I |
probably benign |
Het |
| Clec11a |
C |
T |
7: 43,954,150 (GRCm39) |
A268T |
probably damaging |
Het |
| Ctnna2 |
C |
A |
6: 77,091,912 (GRCm39) |
|
probably null |
Het |
| Diaph3 |
C |
A |
14: 87,222,236 (GRCm39) |
R416L |
probably damaging |
Het |
| Dnmbp |
T |
A |
19: 43,838,315 (GRCm39) |
N1170I |
probably damaging |
Het |
| Erbb2 |
G |
T |
11: 98,318,279 (GRCm39) |
C505F |
probably damaging |
Het |
| Ercc6 |
T |
A |
14: 32,289,479 (GRCm39) |
F904L |
probably damaging |
Het |
| Exo5 |
C |
T |
4: 120,779,514 (GRCm39) |
G117D |
probably damaging |
Het |
| F2 |
CAGAAAG |
CAG |
2: 91,465,302 (GRCm39) |
|
probably benign |
Het |
| Fbxl5 |
A |
G |
5: 43,930,896 (GRCm39) |
Y64H |
probably damaging |
Het |
| Gabra4 |
T |
A |
5: 71,798,207 (GRCm39) |
M207L |
probably damaging |
Het |
| Galnt15 |
T |
C |
14: 31,771,786 (GRCm39) |
L277P |
probably damaging |
Het |
| Gclm |
T |
C |
3: 122,049,261 (GRCm39) |
|
probably null |
Het |
| Gm5493 |
T |
A |
17: 22,966,201 (GRCm39) |
C29S |
possibly damaging |
Het |
| Grik3 |
A |
G |
4: 125,564,382 (GRCm39) |
T455A |
probably benign |
Het |
| Grm3 |
A |
G |
5: 9,639,766 (GRCm39) |
V93A |
probably benign |
Het |
| Hdgfl2 |
C |
T |
17: 56,406,217 (GRCm39) |
A535V |
possibly damaging |
Het |
| Hmcn1 |
T |
A |
1: 150,613,007 (GRCm39) |
D1424V |
probably benign |
Het |
| Hsd3b6 |
C |
T |
3: 98,715,120 (GRCm39) |
V91I |
probably benign |
Het |
| Igdcc4 |
G |
A |
9: 65,030,039 (GRCm39) |
S363N |
possibly damaging |
Het |
| Intu |
T |
C |
3: 40,647,347 (GRCm39) |
V740A |
probably benign |
Het |
| Itga2 |
C |
T |
13: 114,992,717 (GRCm39) |
V838I |
probably benign |
Het |
| Kif9 |
A |
G |
9: 110,318,965 (GRCm39) |
E143G |
probably damaging |
Het |
| Kmt2c |
T |
A |
5: 25,614,205 (GRCm39) |
I172F |
probably benign |
Het |
| Kmt2d |
G |
A |
15: 98,754,043 (GRCm39) |
R21W |
probably damaging |
Het |
| Mdh1b |
A |
T |
1: 63,750,620 (GRCm39) |
D449E |
probably benign |
Het |
| Meis1 |
T |
C |
11: 18,831,785 (GRCm39) |
I418V |
probably benign |
Het |
| Nags |
T |
A |
11: 102,037,395 (GRCm39) |
M162K |
probably damaging |
Het |
| Nufip1 |
A |
G |
14: 76,348,413 (GRCm39) |
D14G |
probably benign |
Het |
| Or2l13 |
T |
A |
16: 19,306,227 (GRCm39) |
I213N |
probably damaging |
Het |
| Or2n1c |
A |
C |
17: 38,519,208 (GRCm39) |
E24A |
possibly damaging |
Het |
| Or7g28 |
T |
G |
9: 19,272,274 (GRCm39) |
I126L |
probably damaging |
Het |
| Osmr |
A |
C |
15: 6,850,560 (GRCm39) |
V681G |
probably damaging |
Het |
| Paxip1 |
G |
T |
5: 27,971,282 (GRCm39) |
Q356K |
unknown |
Het |
| Pcdhac1 |
T |
A |
18: 37,223,595 (GRCm39) |
F136Y |
probably damaging |
Het |
| Pla2g6 |
A |
G |
15: 79,171,328 (GRCm39) |
V699A |
probably benign |
Het |
| Plcb3 |
A |
T |
19: 6,943,578 (GRCm39) |
V107E |
probably damaging |
Het |
| Plch1 |
T |
A |
3: 63,681,136 (GRCm39) |
I164F |
probably damaging |
Het |
| Plpp3 |
A |
T |
4: 105,052,077 (GRCm39) |
I73F |
probably damaging |
Het |
| Plscr5 |
G |
A |
9: 92,080,574 (GRCm39) |
R20Q |
probably benign |
Het |
| Prdm10 |
G |
A |
9: 31,252,779 (GRCm39) |
R504Q |
probably damaging |
Het |
| Prss58 |
T |
C |
6: 40,874,751 (GRCm39) |
Y30C |
probably damaging |
Het |
| Psg19 |
T |
A |
7: 18,530,894 (GRCm39) |
T87S |
probably benign |
Het |
| Ptpn22 |
T |
G |
3: 103,789,418 (GRCm39) |
M294R |
probably benign |
Het |
| Rai1 |
T |
A |
11: 60,079,482 (GRCm39) |
M1182K |
probably benign |
Het |
| Sez6 |
T |
A |
11: 77,867,388 (GRCm39) |
V795D |
possibly damaging |
Het |
| Shcbp1 |
A |
G |
8: 4,789,214 (GRCm39) |
V535A |
possibly damaging |
Het |
| Skint9 |
A |
G |
4: 112,246,447 (GRCm39) |
Y222H |
probably benign |
Het |
| Slc13a3 |
T |
A |
2: 165,253,816 (GRCm39) |
I446F |
probably damaging |
Het |
| Slc2a3 |
C |
T |
6: 122,714,196 (GRCm39) |
R57H |
probably damaging |
Het |
| Slc44a4 |
A |
G |
17: 35,140,219 (GRCm39) |
D208G |
probably benign |
Het |
| Spata31d1b |
A |
T |
13: 59,863,838 (GRCm39) |
N329Y |
possibly damaging |
Het |
| Strbp |
C |
T |
2: 37,517,499 (GRCm39) |
R192K |
probably damaging |
Het |
| Tctn3 |
A |
T |
19: 40,600,548 (GRCm39) |
L14Q |
probably damaging |
Het |
| Tenm2 |
T |
A |
11: 36,834,989 (GRCm39) |
D2V |
probably damaging |
Het |
| Tln2 |
T |
G |
9: 67,241,596 (GRCm39) |
K1003T |
probably benign |
Het |
| Tmem63b |
T |
C |
17: 45,971,800 (GRCm39) |
E805G |
probably damaging |
Het |
| Trhr |
A |
T |
15: 44,060,980 (GRCm39) |
N167Y |
probably damaging |
Het |
| Trpc2 |
A |
G |
7: 101,744,390 (GRCm39) |
R721G |
probably benign |
Het |
| Ttn |
C |
A |
2: 76,701,267 (GRCm39) |
|
probably benign |
Het |
| Wdr91 |
A |
G |
6: 34,869,288 (GRCm39) |
I412T |
probably damaging |
Het |
| Zcchc4 |
T |
A |
5: 52,953,952 (GRCm39) |
S211T |
probably benign |
Het |
|
| Other mutations in Hfm1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00944:Hfm1
|
APN |
5 |
107,049,996 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
IGL01295:Hfm1
|
APN |
5 |
107,065,472 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
IGL01725:Hfm1
|
APN |
5 |
107,065,245 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01758:Hfm1
|
APN |
5 |
107,052,659 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01911:Hfm1
|
APN |
5 |
107,059,410 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL02337:Hfm1
|
APN |
5 |
107,052,133 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02472:Hfm1
|
APN |
5 |
107,021,794 (GRCm39) |
splice site |
probably benign |
|
|
IGL02496:Hfm1
|
APN |
5 |
107,049,627 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL02545:Hfm1
|
APN |
5 |
107,043,153 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02584:Hfm1
|
APN |
5 |
107,026,528 (GRCm39) |
splice site |
probably null |
|
|
IGL02728:Hfm1
|
APN |
5 |
107,026,689 (GRCm39) |
missense |
probably benign |
0.13 |
|
IGL02881:Hfm1
|
APN |
5 |
107,022,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03108:Hfm1
|
APN |
5 |
107,043,800 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03351:Hfm1
|
APN |
5 |
107,059,441 (GRCm39) |
nonsense |
probably null |
|
|
IGL03353:Hfm1
|
APN |
5 |
107,004,795 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0024:Hfm1
|
UTSW |
5 |
107,004,790 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0024:Hfm1
|
UTSW |
5 |
107,004,790 (GRCm39) |
missense |
probably benign |
0.41 |
|
R0094:Hfm1
|
UTSW |
5 |
107,065,344 (GRCm39) |
missense |
probably benign |
|
|
R0633:Hfm1
|
UTSW |
5 |
107,065,467 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R0644:Hfm1
|
UTSW |
5 |
107,046,122 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1078:Hfm1
|
UTSW |
5 |
107,026,696 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1120:Hfm1
|
UTSW |
5 |
107,052,084 (GRCm39) |
splice site |
probably benign |
|
|
R1166:Hfm1
|
UTSW |
5 |
107,059,277 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1242:Hfm1
|
UTSW |
5 |
107,022,767 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1414:Hfm1
|
UTSW |
5 |
107,020,219 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1450:Hfm1
|
UTSW |
5 |
107,066,324 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1529:Hfm1
|
UTSW |
5 |
107,000,989 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1622:Hfm1
|
UTSW |
5 |
107,041,389 (GRCm39) |
missense |
possibly damaging |
0.58 |
|
R1710:Hfm1
|
UTSW |
5 |
107,043,869 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1710:Hfm1
|
UTSW |
5 |
107,028,380 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1757:Hfm1
|
UTSW |
5 |
107,028,226 (GRCm39) |
splice site |
probably null |
|
|
R1856:Hfm1
|
UTSW |
5 |
106,995,542 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1984:Hfm1
|
UTSW |
5 |
107,046,442 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R1985:Hfm1
|
UTSW |
5 |
107,046,442 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2040:Hfm1
|
UTSW |
5 |
107,049,684 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2122:Hfm1
|
UTSW |
5 |
107,044,121 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2426:Hfm1
|
UTSW |
5 |
106,995,519 (GRCm39) |
splice site |
probably null |
|
|
R2474:Hfm1
|
UTSW |
5 |
107,020,282 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R2926:Hfm1
|
UTSW |
5 |
107,022,148 (GRCm39) |
nonsense |
probably null |
|
|
R2944:Hfm1
|
UTSW |
5 |
107,020,196 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3705:Hfm1
|
UTSW |
5 |
107,040,705 (GRCm39) |
unclassified |
probably benign |
|
|
R4256:Hfm1
|
UTSW |
5 |
107,052,663 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4455:Hfm1
|
UTSW |
5 |
107,034,374 (GRCm39) |
splice site |
probably null |
|
|
R4538:Hfm1
|
UTSW |
5 |
107,022,756 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R4540:Hfm1
|
UTSW |
5 |
107,022,087 (GRCm39) |
nonsense |
probably null |
|
|
R4591:Hfm1
|
UTSW |
5 |
106,995,533 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4745:Hfm1
|
UTSW |
5 |
107,049,709 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
R4747:Hfm1
|
UTSW |
5 |
107,065,389 (GRCm39) |
missense |
probably benign |
|
|
R4765:Hfm1
|
UTSW |
5 |
106,990,405 (GRCm39) |
missense |
probably benign |
0.21 |
|
R4821:Hfm1
|
UTSW |
5 |
107,002,606 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4842:Hfm1
|
UTSW |
5 |
107,040,617 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4944:Hfm1
|
UTSW |
5 |
107,022,079 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R5399:Hfm1
|
UTSW |
5 |
107,065,428 (GRCm39) |
missense |
possibly damaging |
0.91 |
|
R5414:Hfm1
|
UTSW |
5 |
107,049,942 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5436:Hfm1
|
UTSW |
5 |
107,040,638 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R5459:Hfm1
|
UTSW |
5 |
107,052,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5485:Hfm1
|
UTSW |
5 |
106,995,528 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5585:Hfm1
|
UTSW |
5 |
107,059,305 (GRCm39) |
missense |
probably benign |
0.05 |
|
R5631:Hfm1
|
UTSW |
5 |
107,052,629 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5705:Hfm1
|
UTSW |
5 |
107,059,319 (GRCm39) |
missense |
probably benign |
0.21 |
|
R5804:Hfm1
|
UTSW |
5 |
107,026,455 (GRCm39) |
splice site |
probably null |
|
|
R5959:Hfm1
|
UTSW |
5 |
107,022,783 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6046:Hfm1
|
UTSW |
5 |
107,046,509 (GRCm39) |
splice site |
probably null |
|
|
R6191:Hfm1
|
UTSW |
5 |
107,034,419 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R6345:Hfm1
|
UTSW |
5 |
106,989,504 (GRCm39) |
missense |
probably benign |
|
|
R6580:Hfm1
|
UTSW |
5 |
106,995,575 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6651:Hfm1
|
UTSW |
5 |
106,995,553 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6761:Hfm1
|
UTSW |
5 |
107,043,145 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6835:Hfm1
|
UTSW |
5 |
107,026,681 (GRCm39) |
nonsense |
probably null |
|
|
R6891:Hfm1
|
UTSW |
5 |
107,065,240 (GRCm39) |
missense |
possibly damaging |
0.49 |
|
R6924:Hfm1
|
UTSW |
5 |
106,998,276 (GRCm39) |
splice site |
probably null |
|
|
R6980:Hfm1
|
UTSW |
5 |
107,028,343 (GRCm39) |
missense |
probably benign |
0.31 |
|
R7054:Hfm1
|
UTSW |
5 |
107,043,909 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7058:Hfm1
|
UTSW |
5 |
107,059,306 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7189:Hfm1
|
UTSW |
5 |
107,049,569 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7250:Hfm1
|
UTSW |
5 |
107,052,197 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7376:Hfm1
|
UTSW |
5 |
107,043,084 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R7577:Hfm1
|
UTSW |
5 |
107,043,909 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7636:Hfm1
|
UTSW |
5 |
107,065,332 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7639:Hfm1
|
UTSW |
5 |
107,046,341 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7639:Hfm1
|
UTSW |
5 |
107,037,791 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7763:Hfm1
|
UTSW |
5 |
107,029,727 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7828:Hfm1
|
UTSW |
5 |
107,029,657 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7905:Hfm1
|
UTSW |
5 |
107,046,419 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8160:Hfm1
|
UTSW |
5 |
107,043,899 (GRCm39) |
missense |
probably null |
0.00 |
|
R8477:Hfm1
|
UTSW |
5 |
107,029,684 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8739:Hfm1
|
UTSW |
5 |
107,046,371 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R8968:Hfm1
|
UTSW |
5 |
107,065,439 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9072:Hfm1
|
UTSW |
5 |
107,046,146 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9073:Hfm1
|
UTSW |
5 |
107,046,146 (GRCm39) |
missense |
probably benign |
0.04 |
|
R9152:Hfm1
|
UTSW |
5 |
106,989,611 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9234:Hfm1
|
UTSW |
5 |
107,041,334 (GRCm39) |
missense |
probably benign |
|
|
R9244:Hfm1
|
UTSW |
5 |
107,022,766 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R9576:Hfm1
|
UTSW |
5 |
107,021,938 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9649:Hfm1
|
UTSW |
5 |
107,066,329 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9743:Hfm1
|
UTSW |
5 |
107,022,125 (GRCm39) |
missense |
possibly damaging |
0.55 |
|
R9782:Hfm1
|
UTSW |
5 |
107,021,896 (GRCm39) |
missense |
probably benign |
0.38 |
|
R9789:Hfm1
|
UTSW |
5 |
107,065,346 (GRCm39) |
missense |
probably benign |
0.00 |
|
Z1177:Hfm1
|
UTSW |
5 |
107,019,686 (GRCm39) |
missense |
probably benign |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TGTCAATGAGATCTGGCACTAATAA -3'
(R):5'- TCACTTTCAGAGATAAACACAGATGAT -3'
Sequencing Primer
(F):5'- GTGGGTATAAGATCCTCACCCTAG -3'
(R):5'- GTCCCTTAAAAATGTAAAATGCT -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation