Incidental Mutation 'R0433:Zdbf2'
| ID |
38886 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Zdbf2
|
| Ensembl Gene |
ENSMUSG00000027520 |
| Gene Name |
zinc finger, DBF-type containing 2 |
| Synonyms |
4930431J08Rik, 9330107J05Rik |
| MMRRC Submission |
038635-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.119)
|
| Stock # |
R0433 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
63312424-63353735 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to C
at 63345302 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Valine to Alanine
at position 1227
(V1227A)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109767
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000029025]
[ENSMUST00000114132]
|
| AlphaFold |
Q5SS00 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000029025
AA Change: V1227A
PolyPhen 2
Score 0.455 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000029025
Gene: ENSMUSG00000027520
AA Change: V1227A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
79 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
405 |
N/A |
INTRINSIC |
|
internal_repeat_6
|
407 |
565 |
7.68e-5 |
PROSPERO |
|
internal_repeat_5
|
418 |
768 |
5.53e-5 |
PROSPERO |
|
internal_repeat_1
|
618 |
873 |
3.17e-15 |
PROSPERO |
|
internal_repeat_4
|
621 |
885 |
2.09e-6 |
PROSPERO |
|
internal_repeat_3
|
642 |
886 |
1.52e-7 |
PROSPERO |
|
internal_repeat_2
|
650 |
912 |
5.87e-11 |
PROSPERO |
|
internal_repeat_6
|
722 |
891 |
7.68e-5 |
PROSPERO |
|
low complexity region
|
965 |
982 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
1061 |
1328 |
2.09e-6 |
PROSPERO |
|
internal_repeat_2
|
1215 |
1484 |
5.87e-11 |
PROSPERO |
|
internal_repeat_3
|
1287 |
1507 |
1.52e-7 |
PROSPERO |
|
internal_repeat_1
|
1307 |
1536 |
3.17e-15 |
PROSPERO |
|
internal_repeat_5
|
1388 |
1758 |
5.53e-5 |
PROSPERO |
|
low complexity region
|
1767 |
1778 |
N/A |
INTRINSIC |
|
low complexity region
|
2211 |
2235 |
N/A |
INTRINSIC |
|
low complexity region
|
2240 |
2399 |
N/A |
INTRINSIC |
|
low complexity region
|
2402 |
2420 |
N/A |
INTRINSIC |
|
low complexity region
|
2446 |
2458 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000114132
AA Change: V1227A
PolyPhen 2
Score 0.455 (Sensitivity: 0.89; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000109767
Gene: ENSMUSG00000027520
AA Change: V1227A
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
79 |
99 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
164 |
N/A |
INTRINSIC |
|
low complexity region
|
378 |
405 |
N/A |
INTRINSIC |
|
internal_repeat_6
|
407 |
565 |
7.68e-5 |
PROSPERO |
|
internal_repeat_5
|
418 |
768 |
5.53e-5 |
PROSPERO |
|
internal_repeat_1
|
618 |
873 |
3.17e-15 |
PROSPERO |
|
internal_repeat_4
|
621 |
885 |
2.09e-6 |
PROSPERO |
|
internal_repeat_3
|
642 |
886 |
1.52e-7 |
PROSPERO |
|
internal_repeat_2
|
650 |
912 |
5.87e-11 |
PROSPERO |
|
internal_repeat_6
|
722 |
891 |
7.68e-5 |
PROSPERO |
|
low complexity region
|
965 |
982 |
N/A |
INTRINSIC |
|
internal_repeat_4
|
1061 |
1328 |
2.09e-6 |
PROSPERO |
|
internal_repeat_2
|
1215 |
1484 |
5.87e-11 |
PROSPERO |
|
internal_repeat_3
|
1287 |
1507 |
1.52e-7 |
PROSPERO |
|
internal_repeat_1
|
1307 |
1536 |
3.17e-15 |
PROSPERO |
|
internal_repeat_5
|
1388 |
1758 |
5.53e-5 |
PROSPERO |
|
low complexity region
|
1767 |
1778 |
N/A |
INTRINSIC |
|
low complexity region
|
2211 |
2235 |
N/A |
INTRINSIC |
|
low complexity region
|
2240 |
2399 |
N/A |
INTRINSIC |
|
low complexity region
|
2402 |
2420 |
N/A |
INTRINSIC |
|
low complexity region
|
2446 |
2458 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.1795 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.5%
- 10x: 96.7%
- 20x: 94.3%
|
| Validation Efficiency |
99% (108/109) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein containing DBF4-type zinc finger domains. This gene is imprinted and paternally expressed in lymphocytes but is more stochastically expressed in the placenta. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Nov 2015]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 102 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 1110032F04Rik |
T |
C |
3: 68,777,636 (GRCm39) |
V199A |
possibly damaging |
Het |
| Abcb5 |
T |
C |
12: 118,841,545 (GRCm39) |
M967V |
probably benign |
Het |
| Adcy10 |
T |
A |
1: 165,379,591 (GRCm39) |
L951Q |
probably damaging |
Het |
| Amer2 |
A |
T |
14: 60,616,032 (GRCm39) |
S76C |
probably damaging |
Het |
| Atad1 |
T |
C |
19: 32,675,877 (GRCm39) |
I182M |
probably benign |
Het |
| Bpi |
A |
G |
2: 158,100,339 (GRCm39) |
D42G |
probably damaging |
Het |
| C7 |
G |
T |
15: 5,018,398 (GRCm39) |
T815K |
probably damaging |
Het |
| Cacna1g |
T |
A |
11: 94,350,033 (GRCm39) |
D604V |
probably benign |
Het |
| Camk1g |
A |
G |
1: 193,036,366 (GRCm39) |
F165L |
probably damaging |
Het |
| Ccdc69 |
C |
T |
11: 54,943,716 (GRCm39) |
|
probably null |
Het |
| Ccser2 |
A |
C |
14: 36,640,486 (GRCm39) |
F37L |
probably damaging |
Het |
| Cfap43 |
A |
G |
19: 47,814,210 (GRCm39) |
F208S |
probably benign |
Het |
| Cfap54 |
G |
A |
10: 92,814,942 (GRCm39) |
|
probably benign |
Het |
| Cfap69 |
A |
C |
5: 5,699,853 (GRCm39) |
D62E |
probably damaging |
Het |
| Cnksr2 |
A |
T |
X: 156,671,554 (GRCm39) |
M483K |
probably benign |
Het |
| Cnksr2 |
C |
A |
X: 156,671,553 (GRCm39) |
M483I |
probably benign |
Het |
| Cog8 |
T |
C |
8: 107,783,110 (GRCm39) |
S60G |
possibly damaging |
Het |
| Col4a3 |
C |
T |
1: 82,647,940 (GRCm39) |
P484S |
unknown |
Het |
| Col6a4 |
C |
T |
9: 105,945,193 (GRCm39) |
G974R |
probably damaging |
Het |
| Cplane1 |
T |
C |
15: 8,246,046 (GRCm39) |
S1473P |
probably benign |
Het |
| Dbnl |
T |
G |
11: 5,746,825 (GRCm39) |
|
probably null |
Het |
| Dhcr7 |
T |
C |
7: 143,394,200 (GRCm39) |
C114R |
possibly damaging |
Het |
| Dnah2 |
C |
A |
11: 69,350,114 (GRCm39) |
D2340Y |
probably damaging |
Het |
| Dnai4 |
T |
C |
4: 102,960,450 (GRCm39) |
N67D |
probably benign |
Het |
| Dusp10 |
T |
A |
1: 183,801,393 (GRCm39) |
Y387N |
probably damaging |
Het |
| Eipr1 |
C |
T |
12: 28,909,330 (GRCm39) |
T199I |
possibly damaging |
Het |
| Emc2 |
T |
G |
15: 43,360,520 (GRCm39) |
|
probably null |
Het |
| Enpp3 |
A |
G |
10: 24,696,495 (GRCm39) |
S147P |
probably benign |
Het |
| Fam133b |
T |
A |
5: 3,608,560 (GRCm39) |
|
probably benign |
Het |
| Fat1 |
C |
A |
8: 45,477,686 (GRCm39) |
T2244K |
possibly damaging |
Het |
| Fbn1 |
A |
G |
2: 125,190,135 (GRCm39) |
S1453P |
possibly damaging |
Het |
| Fez2 |
A |
T |
17: 78,725,476 (GRCm39) |
F13I |
probably damaging |
Het |
| Ggnbp2 |
T |
C |
11: 84,727,246 (GRCm39) |
K530R |
probably damaging |
Het |
| Gpa33 |
T |
C |
1: 165,991,330 (GRCm39) |
|
probably benign |
Het |
| Gpr142 |
T |
C |
11: 114,696,823 (GRCm39) |
I123T |
probably damaging |
Het |
| Il21 |
T |
G |
3: 37,286,684 (GRCm39) |
I11L |
possibly damaging |
Het |
| Klhl7 |
A |
G |
5: 24,332,700 (GRCm39) |
E86G |
probably damaging |
Het |
| Klk10 |
G |
T |
7: 43,430,989 (GRCm39) |
A11S |
possibly damaging |
Het |
| Knl1 |
A |
T |
2: 118,934,542 (GRCm39) |
D2115V |
probably damaging |
Het |
| Lonp2 |
A |
G |
8: 87,360,582 (GRCm39) |
D185G |
probably damaging |
Het |
| Lrrc47 |
T |
C |
4: 154,102,822 (GRCm39) |
|
probably benign |
Het |
| Lrrcc1 |
A |
G |
3: 14,624,434 (GRCm39) |
I698V |
probably damaging |
Het |
| Lzts2 |
T |
C |
19: 45,010,115 (GRCm39) |
V83A |
possibly damaging |
Het |
| Melk |
C |
A |
4: 44,340,614 (GRCm39) |
|
probably benign |
Het |
| Mical1 |
G |
A |
10: 41,355,486 (GRCm39) |
V150I |
probably benign |
Het |
| Morn3 |
C |
A |
5: 123,177,396 (GRCm39) |
M129I |
probably benign |
Het |
| Mroh2b |
T |
A |
15: 4,971,116 (GRCm39) |
D1040E |
probably benign |
Het |
| Mroh5 |
T |
C |
15: 73,661,877 (GRCm39) |
N438S |
probably benign |
Het |
| Mroh5 |
T |
A |
15: 73,662,657 (GRCm39) |
Q387L |
probably damaging |
Het |
| Myh15 |
A |
G |
16: 48,965,599 (GRCm39) |
D1168G |
probably damaging |
Het |
| Nek10 |
A |
G |
14: 14,860,927 (GRCm38) |
E493G |
probably benign |
Het |
| Nipsnap3a |
A |
G |
4: 53,000,316 (GRCm39) |
Y227C |
probably damaging |
Het |
| Nlrp9c |
T |
A |
7: 26,085,244 (GRCm39) |
T112S |
probably benign |
Het |
| Nphp4 |
T |
C |
4: 152,602,629 (GRCm39) |
V401A |
probably benign |
Het |
| Nr1h2 |
A |
G |
7: 44,199,411 (GRCm39) |
*365Q |
probably null |
Het |
| Or13p5 |
T |
C |
4: 118,592,287 (GRCm39) |
V187A |
probably benign |
Het |
| Or5p54 |
T |
C |
7: 107,554,469 (GRCm39) |
I207T |
probably damaging |
Het |
| Pacs2 |
T |
A |
12: 113,020,464 (GRCm39) |
V279D |
possibly damaging |
Het |
| Pdcd2 |
C |
T |
17: 15,746,646 (GRCm39) |
C171Y |
probably benign |
Het |
| Pde11a |
T |
A |
2: 76,168,050 (GRCm39) |
D301V |
possibly damaging |
Het |
| Pfpl |
T |
G |
19: 12,406,839 (GRCm39) |
N363K |
probably damaging |
Het |
| Phf14 |
T |
A |
6: 11,933,742 (GRCm39) |
S201R |
probably damaging |
Het |
| Pip4k2c |
G |
A |
10: 127,044,815 (GRCm39) |
P66S |
probably benign |
Het |
| Pou2f3 |
G |
T |
9: 43,038,693 (GRCm39) |
H392N |
probably benign |
Het |
| Pou3f1 |
G |
T |
4: 124,552,697 (GRCm39) |
G400C |
probably damaging |
Het |
| Ptprg |
T |
C |
14: 12,220,620 (GRCm38) |
I1219T |
probably damaging |
Het |
| Rfx6 |
A |
G |
10: 51,596,124 (GRCm39) |
D435G |
probably damaging |
Het |
| Rhpn2 |
T |
A |
7: 35,084,899 (GRCm39) |
S598T |
probably benign |
Het |
| Sdccag8 |
C |
A |
1: 176,672,387 (GRCm39) |
|
probably null |
Het |
| Sec16b |
C |
A |
1: 157,362,279 (GRCm39) |
Y43* |
probably null |
Het |
| Sele |
T |
C |
1: 163,876,813 (GRCm39) |
Y30H |
possibly damaging |
Het |
| Sgsm2 |
C |
T |
11: 74,749,016 (GRCm39) |
|
probably null |
Het |
| Slc45a2 |
T |
C |
15: 11,025,831 (GRCm39) |
Y394H |
probably benign |
Het |
| Slc4a10 |
T |
G |
2: 62,120,327 (GRCm39) |
I788S |
probably benign |
Het |
| Slmap |
A |
T |
14: 26,174,749 (GRCm39) |
L161* |
probably null |
Het |
| Slx4 |
A |
T |
16: 3,803,882 (GRCm39) |
D977E |
probably benign |
Het |
| Spata31e5 |
A |
T |
1: 28,816,423 (GRCm39) |
Y536* |
probably null |
Het |
| Spata31f3 |
A |
G |
4: 42,874,013 (GRCm39) |
|
probably benign |
Het |
| Spen |
A |
T |
4: 141,211,069 (GRCm39) |
M608K |
unknown |
Het |
| St8sia4 |
G |
C |
1: 95,519,429 (GRCm39) |
T353R |
probably damaging |
Het |
| Stab2 |
G |
T |
10: 86,679,355 (GRCm39) |
|
probably benign |
Het |
| Stx12 |
C |
T |
4: 132,585,741 (GRCm39) |
G213D |
probably damaging |
Het |
| Synj2 |
A |
T |
17: 6,084,123 (GRCm39) |
N270Y |
probably damaging |
Het |
| Tdrd9 |
C |
T |
12: 111,992,015 (GRCm39) |
R438* |
probably null |
Het |
| Tert |
T |
C |
13: 73,775,200 (GRCm39) |
Y18H |
probably damaging |
Het |
| Tph1 |
A |
T |
7: 46,303,245 (GRCm39) |
F244L |
probably damaging |
Het |
| Triobp |
T |
C |
15: 78,852,401 (GRCm39) |
F852L |
possibly damaging |
Het |
| Trpv1 |
T |
C |
11: 73,143,834 (GRCm39) |
|
probably benign |
Het |
| Uggt2 |
A |
T |
14: 119,312,741 (GRCm39) |
|
probably null |
Het |
| Ulk4 |
A |
G |
9: 120,873,885 (GRCm39) |
I1182T |
probably benign |
Het |
| Uqcc1 |
A |
G |
2: 155,752,288 (GRCm39) |
Y98H |
probably damaging |
Het |
| Usp25 |
A |
G |
16: 76,906,105 (GRCm39) |
I854V |
probably benign |
Het |
| Usp50 |
T |
C |
2: 126,603,464 (GRCm39) |
S361G |
probably damaging |
Het |
| Uspl1 |
C |
A |
5: 149,151,625 (GRCm39) |
Q743K |
probably damaging |
Het |
| Vmn2r3 |
A |
G |
3: 64,183,054 (GRCm39) |
V215A |
possibly damaging |
Het |
| Vmn2r61 |
A |
T |
7: 41,915,335 (GRCm39) |
H94L |
probably benign |
Het |
| Vps37c |
T |
C |
19: 10,690,393 (GRCm39) |
V285A |
probably benign |
Het |
| Vwa8 |
T |
C |
14: 79,300,116 (GRCm39) |
V983A |
probably damaging |
Het |
| Zcchc9 |
C |
T |
13: 91,954,081 (GRCm39) |
R58H |
probably benign |
Het |
| Zfp292 |
T |
C |
4: 34,839,959 (GRCm39) |
K64E |
probably damaging |
Het |
| Zfp948 |
A |
G |
17: 21,807,764 (GRCm39) |
T319A |
probably benign |
Het |
| Zp3r |
T |
G |
1: 130,504,870 (GRCm39) |
|
probably benign |
Het |
|
| Other mutations in Zdbf2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00790:Zdbf2
|
APN |
1 |
63,345,673 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
IGL00796:Zdbf2
|
APN |
1 |
63,346,364 (GRCm39) |
missense |
probably benign |
0.04 |
|
IGL00801:Zdbf2
|
APN |
1 |
63,342,197 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
IGL02803:Zdbf2
|
APN |
1 |
63,342,236 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R0143:Zdbf2
|
UTSW |
1 |
63,347,233 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0147:Zdbf2
|
UTSW |
1 |
63,343,165 (GRCm39) |
nonsense |
probably null |
|
|
R0148:Zdbf2
|
UTSW |
1 |
63,343,165 (GRCm39) |
nonsense |
probably null |
|
|
R0502:Zdbf2
|
UTSW |
1 |
63,344,449 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R0645:Zdbf2
|
UTSW |
1 |
63,344,109 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R0765:Zdbf2
|
UTSW |
1 |
63,344,882 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1068:Zdbf2
|
UTSW |
1 |
63,342,589 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1216:Zdbf2
|
UTSW |
1 |
63,342,161 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1235:Zdbf2
|
UTSW |
1 |
63,348,232 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1352:Zdbf2
|
UTSW |
1 |
63,342,212 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1402:Zdbf2
|
UTSW |
1 |
63,342,786 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1402:Zdbf2
|
UTSW |
1 |
63,342,786 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1435:Zdbf2
|
UTSW |
1 |
63,342,199 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1562:Zdbf2
|
UTSW |
1 |
63,342,747 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R1624:Zdbf2
|
UTSW |
1 |
63,343,018 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1635:Zdbf2
|
UTSW |
1 |
63,343,493 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R1644:Zdbf2
|
UTSW |
1 |
63,348,131 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R1662:Zdbf2
|
UTSW |
1 |
63,343,408 (GRCm39) |
nonsense |
probably null |
|
|
R1700:Zdbf2
|
UTSW |
1 |
63,341,900 (GRCm39) |
missense |
unknown |
|
|
R1720:Zdbf2
|
UTSW |
1 |
63,342,436 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R1853:Zdbf2
|
UTSW |
1 |
63,344,701 (GRCm39) |
frame shift |
probably null |
|
|
R1854:Zdbf2
|
UTSW |
1 |
63,344,701 (GRCm39) |
frame shift |
probably null |
|
|
R1973:Zdbf2
|
UTSW |
1 |
63,348,860 (GRCm39) |
missense |
unknown |
|
|
R2336:Zdbf2
|
UTSW |
1 |
63,342,623 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2428:Zdbf2
|
UTSW |
1 |
63,344,774 (GRCm39) |
missense |
probably benign |
0.04 |
|
R3010:Zdbf2
|
UTSW |
1 |
63,342,224 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R3034:Zdbf2
|
UTSW |
1 |
63,343,364 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R3079:Zdbf2
|
UTSW |
1 |
63,346,636 (GRCm39) |
missense |
probably benign |
0.05 |
|
R3196:Zdbf2
|
UTSW |
1 |
63,347,579 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R3711:Zdbf2
|
UTSW |
1 |
63,347,830 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R3845:Zdbf2
|
UTSW |
1 |
63,347,483 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4093:Zdbf2
|
UTSW |
1 |
63,348,940 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R4250:Zdbf2
|
UTSW |
1 |
63,342,020 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4592:Zdbf2
|
UTSW |
1 |
63,345,750 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R4721:Zdbf2
|
UTSW |
1 |
63,347,951 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R4779:Zdbf2
|
UTSW |
1 |
63,342,397 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R4928:Zdbf2
|
UTSW |
1 |
63,347,973 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R4943:Zdbf2
|
UTSW |
1 |
63,342,073 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R5025:Zdbf2
|
UTSW |
1 |
63,342,809 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R5095:Zdbf2
|
UTSW |
1 |
63,348,232 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5149:Zdbf2
|
UTSW |
1 |
63,344,062 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R5326:Zdbf2
|
UTSW |
1 |
63,343,570 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5341:Zdbf2
|
UTSW |
1 |
63,347,092 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5511:Zdbf2
|
UTSW |
1 |
63,344,836 (GRCm39) |
missense |
probably benign |
0.03 |
|
R5809:Zdbf2
|
UTSW |
1 |
63,345,035 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R5902:Zdbf2
|
UTSW |
1 |
63,345,685 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6162:Zdbf2
|
UTSW |
1 |
63,319,977 (GRCm39) |
start gained |
probably benign |
|
|
R6245:Zdbf2
|
UTSW |
1 |
63,343,592 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6332:Zdbf2
|
UTSW |
1 |
63,346,981 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6361:Zdbf2
|
UTSW |
1 |
63,342,480 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6489:Zdbf2
|
UTSW |
1 |
63,346,637 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6517:Zdbf2
|
UTSW |
1 |
63,344,679 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
R6624:Zdbf2
|
UTSW |
1 |
63,343,073 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6643:Zdbf2
|
UTSW |
1 |
63,343,667 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6786:Zdbf2
|
UTSW |
1 |
63,343,679 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R6808:Zdbf2
|
UTSW |
1 |
63,347,687 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R6896:Zdbf2
|
UTSW |
1 |
63,348,031 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R6997:Zdbf2
|
UTSW |
1 |
63,329,925 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7011:Zdbf2
|
UTSW |
1 |
63,345,925 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7058:Zdbf2
|
UTSW |
1 |
63,346,563 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7066:Zdbf2
|
UTSW |
1 |
63,346,718 (GRCm39) |
missense |
probably benign |
|
|
R7177:Zdbf2
|
UTSW |
1 |
63,334,120 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R7184:Zdbf2
|
UTSW |
1 |
63,345,664 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R7273:Zdbf2
|
UTSW |
1 |
63,342,563 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7387:Zdbf2
|
UTSW |
1 |
63,343,198 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7468:Zdbf2
|
UTSW |
1 |
63,346,669 (GRCm39) |
missense |
probably benign |
|
|
R7695:Zdbf2
|
UTSW |
1 |
63,346,529 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7712:Zdbf2
|
UTSW |
1 |
63,344,530 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R7735:Zdbf2
|
UTSW |
1 |
63,343,264 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R7736:Zdbf2
|
UTSW |
1 |
63,347,166 (GRCm39) |
nonsense |
probably null |
|
|
R7759:Zdbf2
|
UTSW |
1 |
63,347,535 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7796:Zdbf2
|
UTSW |
1 |
63,342,583 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R7908:Zdbf2
|
UTSW |
1 |
63,345,986 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7970:Zdbf2
|
UTSW |
1 |
63,343,330 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8076:Zdbf2
|
UTSW |
1 |
63,345,260 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8152:Zdbf2
|
UTSW |
1 |
63,345,572 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8195:Zdbf2
|
UTSW |
1 |
63,343,225 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8272:Zdbf2
|
UTSW |
1 |
63,345,142 (GRCm39) |
missense |
probably benign |
|
|
R8306:Zdbf2
|
UTSW |
1 |
63,343,234 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R8309:Zdbf2
|
UTSW |
1 |
63,345,750 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8323:Zdbf2
|
UTSW |
1 |
63,342,073 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R8400:Zdbf2
|
UTSW |
1 |
63,344,135 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R8443:Zdbf2
|
UTSW |
1 |
63,345,166 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R8460:Zdbf2
|
UTSW |
1 |
63,348,729 (GRCm39) |
small deletion |
probably benign |
|
|
R8528:Zdbf2
|
UTSW |
1 |
63,342,545 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8812:Zdbf2
|
UTSW |
1 |
63,347,272 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8962:Zdbf2
|
UTSW |
1 |
63,347,162 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9061:Zdbf2
|
UTSW |
1 |
63,346,296 (GRCm39) |
missense |
|
|
|
R9072:Zdbf2
|
UTSW |
1 |
63,344,923 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R9232:Zdbf2
|
UTSW |
1 |
63,347,168 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R9257:Zdbf2
|
UTSW |
1 |
63,345,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9411:Zdbf2
|
UTSW |
1 |
63,343,288 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R9470:Zdbf2
|
UTSW |
1 |
63,344,784 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R9606:Zdbf2
|
UTSW |
1 |
63,342,536 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
R9621:Zdbf2
|
UTSW |
1 |
63,342,635 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
RF021:Zdbf2
|
UTSW |
1 |
63,341,811 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
X0018:Zdbf2
|
UTSW |
1 |
63,344,510 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
X0027:Zdbf2
|
UTSW |
1 |
63,347,166 (GRCm39) |
nonsense |
probably null |
|
|
X0057:Zdbf2
|
UTSW |
1 |
63,344,549 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
X0063:Zdbf2
|
UTSW |
1 |
63,344,696 (GRCm39) |
missense |
probably benign |
0.04 |
|
Z1176:Zdbf2
|
UTSW |
1 |
63,343,404 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
Z1177:Zdbf2
|
UTSW |
1 |
63,348,362 (GRCm39) |
missense |
unknown |
|
|
Z1177:Zdbf2
|
UTSW |
1 |
63,343,245 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- CACTCCCTGCCTAAACAAGAGTTCG -3'
(R):5'- TCTTGTGTTGCGTTAGTCACAGCC -3'
Sequencing Primer
(F):5'- TGTCCTTGGAAGATAACAGCC -3'
(R):5'- ACAGCCTGAAGTGGTTCATC -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation