Incidental Mutation 'R5008:Dync2i2'
| ID |
390260 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Dync2i2
|
| Ensembl Gene |
ENSMUSG00000039715 |
| Gene Name |
dynein 2 intermediate chain 2 |
| Synonyms |
3200002I06Rik, Wdr34 |
| MMRRC Submission |
042599-MU
|
| Accession Numbers |
|
| Essential gene? |
Possibly non essential
(E-score: 0.449)
|
| Stock # |
R5008 (G1)
|
| Quality Score |
179 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
29921563-29938891 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
C to A
at 29922781 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Arginine to Leucine
at position 322
(R322L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000109340
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046257]
[ENSMUST00000095083]
[ENSMUST00000100225]
[ENSMUST00000113711]
[ENSMUST00000113717]
[ENSMUST00000113719]
[ENSMUST00000129241]
|
| AlphaFold |
Q5U4F6 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000046257
|
| SMART Domains |
Protein: ENSMUSP00000047792
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1068 |
1.18e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1074 |
1210 |
6.52e-27 |
SMART |
|
SPEC
|
1216 |
1316 |
1.44e-37 |
SMART |
|
SPEC
|
1322 |
1422 |
4.43e-29 |
SMART |
|
SPEC
|
1428 |
1528 |
7.54e-32 |
SMART |
|
SPEC
|
1534 |
1635 |
9.65e-30 |
SMART |
|
SPEC
|
1641 |
1741 |
2.32e-32 |
SMART |
|
SPEC
|
1747 |
1847 |
6.98e-36 |
SMART |
|
SPEC
|
1853 |
1953 |
1.53e-32 |
SMART |
|
SPEC
|
1959 |
2060 |
6.23e-24 |
SMART |
|
SPEC
|
2074 |
2174 |
2.08e-11 |
SMART |
|
SPEC
|
2188 |
2289 |
1.07e-4 |
SMART |
|
EFh
|
2307 |
2335 |
5.78e-7 |
SMART |
|
EFh
|
2350 |
2378 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2382 |
2451 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000095083
|
| SMART Domains |
Protein: ENSMUSP00000092697
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1088 |
1.56e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1094 |
1230 |
6.52e-27 |
SMART |
|
SPEC
|
1236 |
1336 |
1.44e-37 |
SMART |
|
SPEC
|
1342 |
1442 |
4.43e-29 |
SMART |
|
SPEC
|
1448 |
1548 |
7.54e-32 |
SMART |
|
SPEC
|
1554 |
1655 |
9.65e-30 |
SMART |
|
SPEC
|
1661 |
1761 |
2.32e-32 |
SMART |
|
SPEC
|
1767 |
1867 |
6.98e-36 |
SMART |
|
SPEC
|
1873 |
1973 |
1.53e-32 |
SMART |
|
SPEC
|
1979 |
2080 |
6.23e-24 |
SMART |
|
SPEC
|
2094 |
2194 |
2.08e-11 |
SMART |
|
SPEC
|
2208 |
2309 |
1.07e-4 |
SMART |
|
EFh
|
2327 |
2355 |
5.78e-7 |
SMART |
|
EFh
|
2370 |
2398 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2402 |
2471 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000100225
|
| SMART Domains |
Protein: ENSMUSP00000097797
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1088 |
1.56e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1094 |
1230 |
6.52e-27 |
SMART |
|
SPEC
|
1236 |
1336 |
1.44e-37 |
SMART |
|
SPEC
|
1342 |
1442 |
4.43e-29 |
SMART |
|
SPEC
|
1448 |
1548 |
7.54e-32 |
SMART |
|
SPEC
|
1554 |
1660 |
2.06e-24 |
SMART |
|
SPEC
|
1666 |
1766 |
2.32e-32 |
SMART |
|
SPEC
|
1772 |
1872 |
6.98e-36 |
SMART |
|
SPEC
|
1878 |
1978 |
1.53e-32 |
SMART |
|
SPEC
|
1984 |
2085 |
6.23e-24 |
SMART |
|
SPEC
|
2099 |
2199 |
2.08e-11 |
SMART |
|
SPEC
|
2213 |
2314 |
1.07e-4 |
SMART |
|
EFh
|
2332 |
2360 |
5.78e-7 |
SMART |
|
EFh
|
2375 |
2403 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2407 |
2476 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113711
AA Change: R322L
PolyPhen 2
Score 0.137 (Sensitivity: 0.92; Specificity: 0.86)
|
| SMART Domains |
Protein: ENSMUSP00000109340
Gene: ENSMUSG00000039715
AA Change: R322L
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
11 |
36 |
N/A |
INTRINSIC |
|
low complexity region
|
90 |
100 |
N/A |
INTRINSIC |
|
Blast:WD40
|
146 |
200 |
3e-28 |
BLAST |
|
WD40
|
207 |
247 |
2e-1 |
SMART |
|
WD40
|
256 |
300 |
3.42e1 |
SMART |
|
Blast:WD40
|
323 |
364 |
8e-10 |
BLAST |
|
WD40
|
382 |
422 |
1.66e-5 |
SMART |
|
WD40
|
425 |
465 |
3.09e-1 |
SMART |
|
WD40
|
470 |
512 |
4.18e-2 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113717
|
| SMART Domains |
Protein: ENSMUSP00000109346
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1068 |
1.18e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1074 |
1210 |
6.52e-27 |
SMART |
|
SPEC
|
1216 |
1316 |
1.44e-37 |
SMART |
|
SPEC
|
1322 |
1422 |
4.43e-29 |
SMART |
|
SPEC
|
1428 |
1528 |
7.54e-32 |
SMART |
|
SPEC
|
1534 |
1640 |
2.06e-24 |
SMART |
|
SPEC
|
1646 |
1746 |
2.32e-32 |
SMART |
|
SPEC
|
1752 |
1852 |
6.98e-36 |
SMART |
|
SPEC
|
1858 |
1958 |
1.53e-32 |
SMART |
|
SPEC
|
1964 |
2065 |
6.23e-24 |
SMART |
|
SPEC
|
2079 |
2179 |
2.08e-11 |
SMART |
|
SPEC
|
2193 |
2294 |
1.07e-4 |
SMART |
|
EFh
|
2312 |
2340 |
5.78e-7 |
SMART |
|
EFh
|
2355 |
2383 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2387 |
2456 |
6.74e-32 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000113719
|
| SMART Domains |
Protein: ENSMUSP00000109348
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
SPEC
|
47 |
146 |
2.1e-30 |
SMART |
|
SPEC
|
152 |
252 |
2.6e-35 |
SMART |
|
SPEC
|
258 |
358 |
4.93e-36 |
SMART |
|
SPEC
|
364 |
464 |
1.08e-27 |
SMART |
|
SPEC
|
470 |
570 |
9.01e-30 |
SMART |
|
SPEC
|
576 |
675 |
3.52e-32 |
SMART |
|
SPEC
|
681 |
781 |
2.15e-36 |
SMART |
|
SPEC
|
787 |
887 |
2.45e-40 |
SMART |
|
SPEC
|
893 |
1068 |
1.18e-24 |
SMART |
|
SH3
|
970 |
1025 |
8.24e-18 |
SMART |
|
SPEC
|
1074 |
1210 |
6.52e-27 |
SMART |
|
SPEC
|
1216 |
1316 |
1.44e-37 |
SMART |
|
SPEC
|
1322 |
1422 |
4.43e-29 |
SMART |
|
SPEC
|
1428 |
1528 |
7.54e-32 |
SMART |
|
SPEC
|
1534 |
1640 |
2.06e-24 |
SMART |
|
SPEC
|
1646 |
1746 |
2.32e-32 |
SMART |
|
SPEC
|
1752 |
1852 |
6.98e-36 |
SMART |
|
SPEC
|
1858 |
1958 |
1.53e-32 |
SMART |
|
SPEC
|
1964 |
2065 |
6.23e-24 |
SMART |
|
SPEC
|
2079 |
2179 |
2.08e-11 |
SMART |
|
SPEC
|
2193 |
2315 |
3.27e0 |
SMART |
|
EFh
|
2333 |
2361 |
5.78e-7 |
SMART |
|
EFh
|
2376 |
2404 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
2408 |
2477 |
6.74e-32 |
SMART |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000124494
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000201758
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000139145
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000152453
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000143892
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129241
|
| SMART Domains |
Protein: ENSMUSP00000121116
Gene: ENSMUSG00000057738
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:Spectrin
|
1 |
65 |
9.9e-10 |
PFAM |
|
SPEC
|
78 |
178 |
2.08e-11 |
SMART |
|
SPEC
|
192 |
314 |
3.27e0 |
SMART |
|
EFh
|
332 |
360 |
5.78e-7 |
SMART |
|
EFh
|
375 |
403 |
3.85e-3 |
SMART |
|
efhand_Ca_insen
|
407 |
476 |
6.74e-32 |
SMART |
|
| Meta Mutation Damage Score |
0.3280 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.6%
- 10x: 97.1%
- 20x: 94.7%
|
| Validation Efficiency |
97% (73/75) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a member of the WD repeat protein family. WD repeats are minimally conserved regions of approximately 40 amino acids typically bracketed by gly-his and trp-asp (GH-WD), which may facilitate formation of heterotrimeric or multiprotein complexes. Members of this family are involved in a variety of cellular processes, including cell cycle progression, signal transduction, apoptosis, and gene regulation. Defects in this gene are a cause of short-rib thoracic dysplasia 11 with or without polydactyly. [provided by RefSeq, Mar 2014]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 62 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 2310022A10Rik |
C |
G |
7: 27,278,192 (GRCm39) |
T242R |
probably damaging |
Het |
| 2310057N15Rik |
A |
G |
16: 88,570,663 (GRCm39) |
Y126H |
probably damaging |
Het |
| Catsperg1 |
A |
T |
7: 28,894,859 (GRCm39) |
Y579* |
probably null |
Het |
| Chchd5 |
A |
T |
2: 128,972,319 (GRCm39) |
|
probably null |
Het |
| Chd1l |
T |
C |
3: 97,491,224 (GRCm39) |
N423D |
probably damaging |
Het |
| Cntnap1 |
G |
A |
11: 101,079,567 (GRCm39) |
W1268* |
probably null |
Het |
| Col2a1 |
G |
A |
15: 97,877,550 (GRCm39) |
A1011V |
probably benign |
Het |
| Cst11 |
A |
G |
2: 148,612,325 (GRCm39) |
I104T |
probably benign |
Het |
| Dctd |
C |
T |
8: 48,590,449 (GRCm39) |
|
probably benign |
Het |
| Dnaaf4 |
T |
C |
9: 72,879,600 (GRCm39) |
|
probably benign |
Het |
| Dnah17 |
A |
G |
11: 118,001,403 (GRCm39) |
F847L |
probably benign |
Het |
| Dspp |
A |
T |
5: 104,323,439 (GRCm39) |
H194L |
possibly damaging |
Het |
| Frmd5 |
C |
A |
2: 121,379,341 (GRCm39) |
R414L |
probably damaging |
Het |
| Galnt3 |
C |
A |
2: 65,915,585 (GRCm39) |
R592L |
probably benign |
Het |
| Gm38706 |
T |
A |
6: 130,461,580 (GRCm39) |
|
noncoding transcript |
Het |
| Gm38706 |
T |
A |
6: 130,461,983 (GRCm39) |
|
noncoding transcript |
Het |
| Hivep3 |
A |
G |
4: 119,956,114 (GRCm39) |
K1477E |
probably benign |
Het |
| Igsf3 |
C |
T |
3: 101,358,233 (GRCm39) |
T708M |
probably damaging |
Het |
| Ikzf4 |
T |
G |
10: 128,477,119 (GRCm39) |
E64A |
probably benign |
Het |
| Klhl28 |
C |
T |
12: 65,004,001 (GRCm39) |
E171K |
probably damaging |
Het |
| Krt87 |
T |
A |
15: 101,389,105 (GRCm39) |
I76F |
probably damaging |
Het |
| Lat2 |
A |
G |
5: 134,631,991 (GRCm39) |
V152A |
probably benign |
Het |
| Lrp12 |
C |
T |
15: 39,741,852 (GRCm39) |
D288N |
probably damaging |
Het |
| Mdp1 |
C |
T |
14: 55,896,683 (GRCm39) |
R126Q |
probably damaging |
Het |
| Msh2 |
C |
A |
17: 88,030,841 (GRCm39) |
A906E |
probably benign |
Het |
| Muc6 |
G |
A |
7: 141,223,981 (GRCm39) |
|
probably benign |
Het |
| Myh4 |
T |
A |
11: 67,144,358 (GRCm39) |
S1243T |
probably benign |
Het |
| Myo3b |
T |
A |
2: 70,088,412 (GRCm39) |
F892I |
probably damaging |
Het |
| Nckap5l |
T |
C |
15: 99,323,731 (GRCm39) |
N924S |
possibly damaging |
Het |
| Npnt |
C |
T |
3: 132,612,218 (GRCm39) |
C218Y |
probably damaging |
Het |
| Or2a20 |
T |
A |
6: 43,193,991 (GRCm39) |
I48N |
probably damaging |
Het |
| Or2d2b |
A |
T |
7: 106,705,288 (GRCm39) |
M260K |
probably damaging |
Het |
| Or7a42 |
T |
A |
10: 78,791,905 (GRCm39) |
F289I |
probably damaging |
Het |
| Pfkm |
G |
A |
15: 98,020,570 (GRCm39) |
C233Y |
probably benign |
Het |
| Pigq |
A |
G |
17: 26,153,177 (GRCm39) |
V338A |
probably benign |
Het |
| Pld4 |
A |
T |
12: 112,734,484 (GRCm39) |
N415I |
possibly damaging |
Het |
| Pmm1 |
A |
T |
15: 81,842,095 (GRCm39) |
|
probably null |
Het |
| Polg |
G |
T |
7: 79,109,822 (GRCm39) |
P394T |
probably damaging |
Het |
| Polq |
A |
T |
16: 36,882,749 (GRCm39) |
I1359L |
probably benign |
Het |
| Pramel30 |
A |
G |
4: 144,057,836 (GRCm39) |
S148G |
probably benign |
Het |
| Pros1 |
A |
G |
16: 62,748,548 (GRCm39) |
N674D |
possibly damaging |
Het |
| Psme4 |
T |
A |
11: 30,806,896 (GRCm39) |
|
probably benign |
Het |
| Rasa3 |
A |
T |
8: 13,634,959 (GRCm39) |
C453* |
probably null |
Het |
| Repin1 |
T |
C |
6: 48,573,542 (GRCm39) |
V101A |
probably damaging |
Het |
| Rnf186 |
A |
T |
4: 138,694,540 (GRCm39) |
M27L |
probably benign |
Het |
| Rpa1 |
A |
G |
11: 75,204,125 (GRCm39) |
|
probably null |
Het |
| Rph3a |
G |
T |
5: 121,083,454 (GRCm39) |
N605K |
probably damaging |
Het |
| Rps18 |
A |
T |
17: 34,171,258 (GRCm39) |
|
probably null |
Het |
| Scgn |
A |
G |
13: 24,174,958 (GRCm39) |
I20T |
probably damaging |
Het |
| Skint6 |
A |
T |
4: 112,848,452 (GRCm39) |
V652E |
possibly damaging |
Het |
| Slc23a2 |
T |
C |
2: 131,943,414 (GRCm39) |
H29R |
probably damaging |
Het |
| Slc34a3 |
C |
T |
2: 25,120,854 (GRCm39) |
V383I |
possibly damaging |
Het |
| Slc5a1 |
A |
G |
5: 33,309,917 (GRCm39) |
M382V |
possibly damaging |
Het |
| Slc5a3 |
T |
A |
16: 91,874,169 (GRCm39) |
S75R |
probably damaging |
Het |
| Stat5b |
G |
C |
11: 100,693,309 (GRCm39) |
H111D |
probably benign |
Het |
| Tanc2 |
G |
A |
11: 105,515,886 (GRCm39) |
M1I |
probably null |
Het |
| Tbcel |
C |
T |
9: 42,327,419 (GRCm39) |
G328E |
probably damaging |
Het |
| Tecta |
C |
A |
9: 42,284,358 (GRCm39) |
R909L |
possibly damaging |
Het |
| Tnip1 |
A |
T |
11: 54,828,810 (GRCm39) |
M119K |
probably benign |
Het |
| Zbbx |
A |
C |
3: 75,058,755 (GRCm39) |
S51A |
possibly damaging |
Het |
| Zc3h12c |
T |
C |
9: 52,028,000 (GRCm39) |
N454S |
probably benign |
Het |
| Zfp980 |
G |
A |
4: 145,428,653 (GRCm39) |
G461S |
probably benign |
Het |
|
| Other mutations in Dync2i2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL02007:Dync2i2
|
APN |
2 |
29,928,402 (GRCm39) |
missense |
probably benign |
0.11 |
|
IGL02165:Dync2i2
|
APN |
2 |
29,922,172 (GRCm39) |
missense |
probably benign |
|
|
IGL02600:Dync2i2
|
APN |
2 |
29,923,314 (GRCm39) |
missense |
possibly damaging |
0.65 |
|
PIT1430001:Dync2i2
|
UTSW |
2 |
29,922,147 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0542:Dync2i2
|
UTSW |
2 |
29,921,837 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R4065:Dync2i2
|
UTSW |
2 |
29,922,820 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4067:Dync2i2
|
UTSW |
2 |
29,922,820 (GRCm39) |
missense |
probably benign |
0.03 |
|
R4750:Dync2i2
|
UTSW |
2 |
29,923,932 (GRCm39) |
missense |
probably benign |
0.00 |
|
R4907:Dync2i2
|
UTSW |
2 |
29,922,472 (GRCm39) |
splice site |
probably null |
|
|
R5253:Dync2i2
|
UTSW |
2 |
29,922,375 (GRCm39) |
unclassified |
probably benign |
|
|
R6014:Dync2i2
|
UTSW |
2 |
29,921,763 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6456:Dync2i2
|
UTSW |
2 |
29,922,779 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6789:Dync2i2
|
UTSW |
2 |
29,923,284 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7024:Dync2i2
|
UTSW |
2 |
29,928,278 (GRCm39) |
missense |
possibly damaging |
0.61 |
|
R7319:Dync2i2
|
UTSW |
2 |
29,928,341 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7576:Dync2i2
|
UTSW |
2 |
29,938,790 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7640:Dync2i2
|
UTSW |
2 |
29,921,780 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8025:Dync2i2
|
UTSW |
2 |
29,938,730 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8111:Dync2i2
|
UTSW |
2 |
29,921,859 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8273:Dync2i2
|
UTSW |
2 |
29,921,903 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8277:Dync2i2
|
UTSW |
2 |
29,923,886 (GRCm39) |
missense |
probably benign |
|
|
R8309:Dync2i2
|
UTSW |
2 |
29,922,201 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8724:Dync2i2
|
UTSW |
2 |
29,923,961 (GRCm39) |
missense |
probably benign |
0.11 |
|
R8732:Dync2i2
|
UTSW |
2 |
29,922,220 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R8837:Dync2i2
|
UTSW |
2 |
29,928,374 (GRCm39) |
missense |
probably benign |
0.03 |
|
R9149:Dync2i2
|
UTSW |
2 |
29,923,953 (GRCm39) |
missense |
probably benign |
0.26 |
|
R9190:Dync2i2
|
UTSW |
2 |
29,922,211 (GRCm39) |
missense |
probably benign |
0.05 |
|
R9557:Dync2i2
|
UTSW |
2 |
29,922,534 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
| Predicted Primers |
PCR Primer
(F):5'- TGCCCAGAACGAAAAGGCTG -3'
(R):5'- CTGATACTGGGGATGCTTCTC -3'
Sequencing Primer
(F):5'- CTGGAGAAGGCCACTGATGTC -3'
(R):5'- GATACTGGGGATGCTTCTCTCTATC -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation