Incidental Mutation 'R5009:Nisch'
| ID |
390388 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Nisch
|
| Ensembl Gene |
ENSMUSG00000021910 |
| Gene Name |
nischarin |
| Synonyms |
1200007D05Rik, edsn, 3202002H23Rik |
| MMRRC Submission |
042600-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5009 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
14 |
| Chromosomal Location |
30892885-30928783 bp(-) (GRCm39) |
| Type of Mutation |
unclassified |
| DNA Base Change (assembly) |
C to T
at 30909186 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000022469]
[ENSMUST00000164989]
[ENSMUST00000165981]
[ENSMUST00000172142]
[ENSMUST00000168206]
|
| AlphaFold |
Q80TM9 |
| Predicted Effect |
unknown
Transcript: ENSMUST00000022469
AA Change: V337M
|
| SMART Domains |
Protein: ENSMUSP00000022469
Gene: ENSMUSG00000021910
AA Change: V337M
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
15 |
119 |
2.17e-26 |
SMART |
|
PDB:4PQ8|A
|
287 |
420 |
9e-8 |
PDB |
|
SCOP:d1h6ta2
|
291 |
421 |
6e-29 |
SMART |
|
Blast:LRR
|
311 |
332 |
5e-6 |
BLAST |
|
Blast:LRR
|
333 |
355 |
6e-6 |
BLAST |
|
Blast:LRR
|
378 |
403 |
5e-7 |
BLAST |
|
Blast:LRR
|
403 |
429 |
6e-7 |
BLAST |
|
low complexity region
|
489 |
501 |
N/A |
INTRINSIC |
|
low complexity region
|
517 |
534 |
N/A |
INTRINSIC |
|
coiled coil region
|
625 |
650 |
N/A |
INTRINSIC |
|
low complexity region
|
662 |
695 |
N/A |
INTRINSIC |
|
low complexity region
|
1038 |
1069 |
N/A |
INTRINSIC |
|
low complexity region
|
1081 |
1193 |
N/A |
INTRINSIC |
|
low complexity region
|
1491 |
1509 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000163846
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000164000
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000164956
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000164989
|
| SMART Domains |
Protein: ENSMUSP00000126982
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
15 |
119 |
2.17e-26 |
SMART |
|
Pfam:LRR_4
|
289 |
332 |
3.2e-8 |
PFAM |
|
Pfam:LRR_1
|
290 |
311 |
2.9e-3 |
PFAM |
|
Pfam:LRR_1
|
313 |
332 |
4.2e-2 |
PFAM |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000165981
AA Change: V337M
|
| SMART Domains |
Protein: ENSMUSP00000130210
Gene: ENSMUSG00000021910
AA Change: V337M
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
15 |
119 |
2.17e-26 |
SMART |
|
Pfam:LRR_7
|
289 |
305 |
7.4e-2 |
PFAM |
|
Pfam:LRR_6
|
289 |
309 |
3.8e-2 |
PFAM |
|
Pfam:LRR_4
|
289 |
333 |
5.9e-8 |
PFAM |
|
Pfam:LRR_8
|
289 |
346 |
6.8e-10 |
PFAM |
|
Pfam:LRR_1
|
290 |
311 |
4.4e-3 |
PFAM |
|
Pfam:LRR_8
|
312 |
369 |
7.3e-9 |
PFAM |
|
Pfam:LRR_1
|
313 |
333 |
1.8e-2 |
PFAM |
|
Pfam:LRR_4
|
329 |
377 |
2.3e-8 |
PFAM |
|
Pfam:LRR_6
|
333 |
354 |
2e-3 |
PFAM |
|
Pfam:LRR_7
|
334 |
350 |
1.9e-1 |
PFAM |
|
Pfam:LRR_1
|
335 |
354 |
1.2e-2 |
PFAM |
|
Blast:LRR
|
378 |
403 |
1e-6 |
BLAST |
|
Blast:LRR
|
403 |
429 |
1e-7 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000167223
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000167979
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000172142
AA Change: V337M
|
| SMART Domains |
Protein: ENSMUSP00000132413
Gene: ENSMUSG00000021910
AA Change: V337M
| Domain | Start | End | E-Value | Type |
|---|
|
PX
|
15 |
119 |
2.17e-26 |
SMART |
|
Pfam:LRR_7
|
289 |
305 |
8.2e-2 |
PFAM |
|
Pfam:LRR_6
|
289 |
309 |
4.2e-2 |
PFAM |
|
Pfam:LRR_4
|
289 |
333 |
6.6e-8 |
PFAM |
|
Pfam:LRR_8
|
289 |
346 |
7.6e-10 |
PFAM |
|
Pfam:LRR_1
|
290 |
311 |
4.9e-3 |
PFAM |
|
Pfam:LRR_8
|
312 |
369 |
7.7e-9 |
PFAM |
|
Pfam:LRR_1
|
313 |
333 |
2e-2 |
PFAM |
|
Pfam:LRR_4
|
329 |
377 |
2.7e-8 |
PFAM |
|
Pfam:LRR_6
|
333 |
354 |
2.2e-3 |
PFAM |
|
Pfam:LRR_7
|
334 |
350 |
2.1e-1 |
PFAM |
|
Pfam:LRR_1
|
335 |
354 |
1.3e-2 |
PFAM |
|
Blast:LRR
|
378 |
403 |
1e-6 |
BLAST |
|
Blast:LRR
|
403 |
429 |
1e-7 |
BLAST |
|
low complexity region
|
489 |
501 |
N/A |
INTRINSIC |
|
| Predicted Effect |
unknown
Transcript: ENSMUST00000168206
AA Change: V92M
|
| SMART Domains |
Protein: ENSMUSP00000132842
Gene: ENSMUSG00000021910
AA Change: V92M
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:LRR_8
|
44 |
101 |
3.9e-9 |
PFAM |
|
Pfam:LRR_1
|
45 |
66 |
2.6e-2 |
PFAM |
|
Pfam:LRR_6
|
88 |
109 |
1.1e-2 |
PFAM |
|
Pfam:LRR_4
|
89 |
132 |
6.5e-8 |
PFAM |
|
Pfam:LRR_1
|
90 |
109 |
6.9e-2 |
PFAM |
|
Blast:LRR
|
133 |
158 |
4e-7 |
BLAST |
|
Blast:LRR
|
158 |
184 |
6e-7 |
BLAST |
|
low complexity region
|
244 |
256 |
N/A |
INTRINSIC |
|
low complexity region
|
272 |
289 |
N/A |
INTRINSIC |
|
coiled coil region
|
380 |
405 |
N/A |
INTRINSIC |
|
low complexity region
|
417 |
450 |
N/A |
INTRINSIC |
|
low complexity region
|
793 |
824 |
N/A |
INTRINSIC |
|
low complexity region
|
836 |
948 |
N/A |
INTRINSIC |
|
low complexity region
|
1246 |
1264 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000170343
|
| SMART Domains |
Protein: ENSMUSP00000130246
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:LRR_8
|
74 |
131 |
2.3e-8 |
PFAM |
|
Blast:LRR
|
140 |
165 |
7e-7 |
BLAST |
|
Blast:LRR
|
165 |
191 |
6e-8 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000172370
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170436
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000170253
|
| SMART Domains |
Protein: ENSMUSP00000129547
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1dcea3
|
2 |
86 |
3e-11 |
SMART |
|
Blast:LRR
|
13 |
34 |
1e-5 |
BLAST |
|
Blast:LRR
|
35 |
60 |
1e-7 |
BLAST |
|
Blast:LRR
|
60 |
86 |
2e-8 |
BLAST |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000168451
|
| SMART Domains |
Protein: ENSMUSP00000132912
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:PX
|
4 |
53 |
5.5e-8 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000169149
|
| SMART Domains |
Protein: ENSMUSP00000131623
Gene: ENSMUSG00000021910
| Domain | Start | End | E-Value | Type |
|---|
|
Blast:PX
|
2 |
27 |
1e-10 |
BLAST |
|
PDB:3P0C|B
|
2 |
33 |
7e-12 |
PDB |
|
| Meta Mutation Damage Score |
0.1454 |
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.6%
- 20x: 93.5%
|
| Validation Efficiency |
100% (91/91) |
| MGI Phenotype |
PHENOTYPE: Mice homozygous for either a knock-out or hypomorphic allele exhibit hearing loss associated with increased susceptibility to otitis media. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Afg2a |
T |
A |
3: 37,487,426 (GRCm39) |
|
probably benign |
Het |
| Aim2 |
T |
C |
1: 173,282,932 (GRCm39) |
Y5H |
probably damaging |
Het |
| Atosa |
G |
A |
9: 74,916,171 (GRCm39) |
E257K |
probably damaging |
Het |
| Atp7b |
A |
G |
8: 22,517,714 (GRCm39) |
S375P |
possibly damaging |
Het |
| BC106179 |
C |
A |
16: 23,043,192 (GRCm39) |
|
probably benign |
Het |
| Brinp3 |
T |
A |
1: 146,776,787 (GRCm39) |
N411K |
probably benign |
Het |
| Cacna1d |
A |
G |
14: 29,801,289 (GRCm39) |
V1386A |
probably damaging |
Het |
| Cuzd1 |
T |
A |
7: 130,913,252 (GRCm39) |
Y455F |
probably damaging |
Het |
| Dctd |
C |
T |
8: 48,590,449 (GRCm39) |
|
probably benign |
Het |
| Dip2b |
T |
A |
15: 100,093,665 (GRCm39) |
|
probably null |
Het |
| Dot1l |
G |
T |
10: 80,607,030 (GRCm39) |
R108L |
probably benign |
Het |
| Dysf |
T |
C |
6: 84,128,968 (GRCm39) |
S1413P |
probably damaging |
Het |
| Eea1 |
C |
A |
10: 95,846,883 (GRCm39) |
R388S |
probably benign |
Het |
| Elavl1 |
C |
T |
8: 4,351,723 (GRCm39) |
R131Q |
probably benign |
Het |
| Erich6b |
A |
G |
14: 75,902,596 (GRCm39) |
T138A |
possibly damaging |
Het |
| Esr1 |
C |
T |
10: 4,662,394 (GRCm39) |
T4I |
probably damaging |
Het |
| Ets1 |
T |
C |
9: 32,644,295 (GRCm39) |
S152P |
possibly damaging |
Het |
| Fcsk |
C |
T |
8: 111,614,462 (GRCm39) |
C609Y |
probably damaging |
Het |
| Flrt2 |
T |
C |
12: 95,746,547 (GRCm39) |
V295A |
probably damaging |
Het |
| Gm13196 |
A |
G |
2: 4,705,149 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5965 |
T |
A |
16: 88,575,312 (GRCm39) |
Y162N |
probably benign |
Het |
| Gm7853 |
A |
T |
14: 35,811,466 (GRCm39) |
|
noncoding transcript |
Het |
| Gm8126 |
C |
T |
14: 43,119,065 (GRCm39) |
A178V |
probably benign |
Het |
| Gpihbp1 |
A |
T |
15: 75,469,570 (GRCm39) |
|
probably benign |
Het |
| Greb1 |
T |
C |
12: 16,774,858 (GRCm39) |
T180A |
possibly damaging |
Het |
| Gsdme |
C |
T |
6: 50,222,992 (GRCm39) |
V108M |
possibly damaging |
Het |
| Gtpbp4 |
T |
C |
13: 9,039,102 (GRCm39) |
Y157C |
probably benign |
Het |
| Gvin3 |
A |
G |
7: 106,200,767 (GRCm39) |
|
noncoding transcript |
Het |
| Hivep1 |
T |
A |
13: 42,312,229 (GRCm39) |
F1490I |
probably benign |
Het |
| Il17ra |
T |
C |
6: 120,459,168 (GRCm39) |
V773A |
probably benign |
Het |
| Kctd8 |
T |
A |
5: 69,268,076 (GRCm39) |
T345S |
probably benign |
Het |
| Kdm3b |
T |
C |
18: 34,957,763 (GRCm39) |
S1243P |
probably benign |
Het |
| Klhdc1 |
T |
C |
12: 69,298,712 (GRCm39) |
V99A |
possibly damaging |
Het |
| Lars1 |
T |
G |
18: 42,354,612 (GRCm39) |
E778D |
probably benign |
Het |
| Map7 |
C |
T |
10: 20,137,664 (GRCm39) |
R279* |
probably null |
Het |
| Mdp1 |
C |
T |
14: 55,896,683 (GRCm39) |
R126Q |
probably damaging |
Het |
| Mtbp |
A |
G |
15: 55,466,583 (GRCm39) |
D532G |
probably benign |
Het |
| Mylk |
G |
A |
16: 34,719,877 (GRCm39) |
V597I |
probably benign |
Het |
| Necab1 |
A |
G |
4: 14,947,503 (GRCm39) |
|
probably benign |
Het |
| Nlrp1a |
T |
C |
11: 71,013,531 (GRCm39) |
D573G |
probably benign |
Het |
| Noct |
C |
A |
3: 51,155,482 (GRCm39) |
N83K |
probably damaging |
Het |
| Or10am5 |
A |
G |
7: 6,517,546 (GRCm39) |
L294P |
probably damaging |
Het |
| Or1b1 |
C |
T |
2: 36,995,467 (GRCm39) |
R65H |
possibly damaging |
Het |
| Or2a12 |
C |
A |
6: 42,904,367 (GRCm39) |
D67E |
probably damaging |
Het |
| Or2ad1 |
T |
C |
13: 21,326,435 (GRCm39) |
N264S |
probably benign |
Het |
| Or52n4b |
A |
G |
7: 108,144,055 (GRCm39) |
I106V |
probably benign |
Het |
| Or6b13 |
C |
T |
7: 139,781,751 (GRCm39) |
A311T |
probably benign |
Het |
| Or6c201 |
T |
C |
10: 128,969,484 (GRCm39) |
H51R |
probably benign |
Het |
| Osgepl1 |
T |
A |
1: 53,357,339 (GRCm39) |
V167D |
probably damaging |
Het |
| Pabpc6 |
T |
C |
17: 9,887,489 (GRCm39) |
E354G |
probably damaging |
Het |
| Pgghg |
A |
C |
7: 140,523,303 (GRCm39) |
D194A |
probably benign |
Het |
| Podnl1 |
A |
T |
8: 84,852,887 (GRCm39) |
H19L |
probably benign |
Het |
| Pold1 |
G |
T |
7: 44,183,326 (GRCm39) |
A977E |
probably benign |
Het |
| Poldip3 |
T |
C |
15: 83,017,395 (GRCm39) |
T227A |
probably damaging |
Het |
| Prss43 |
A |
G |
9: 110,656,489 (GRCm39) |
S59G |
possibly damaging |
Het |
| Ptpn14 |
T |
A |
1: 189,582,731 (GRCm39) |
I526N |
probably benign |
Het |
| Ptprb |
T |
C |
10: 116,184,032 (GRCm39) |
S1615P |
possibly damaging |
Het |
| Ptpro |
A |
G |
6: 137,354,130 (GRCm39) |
K169E |
probably damaging |
Het |
| Rab15 |
T |
C |
12: 76,847,341 (GRCm39) |
E114G |
probably damaging |
Het |
| Rcvrn |
A |
G |
11: 67,586,550 (GRCm39) |
E103G |
probably benign |
Het |
| Repin1 |
T |
A |
6: 48,571,779 (GRCm39) |
|
probably benign |
Het |
| Rita1 |
T |
A |
5: 120,749,448 (GRCm39) |
K88N |
probably damaging |
Het |
| Rtkn2 |
T |
C |
10: 67,877,239 (GRCm39) |
V433A |
probably benign |
Het |
| Runx1t1 |
T |
C |
4: 13,865,231 (GRCm39) |
I314T |
possibly damaging |
Het |
| Serpinb9c |
A |
C |
13: 33,338,414 (GRCm39) |
S190A |
probably benign |
Het |
| Shank2 |
C |
A |
7: 143,623,916 (GRCm39) |
H300Q |
probably benign |
Het |
| Slc4a4 |
A |
G |
5: 89,297,157 (GRCm39) |
|
probably null |
Het |
| Slc5a8 |
T |
C |
10: 88,745,516 (GRCm39) |
S375P |
probably benign |
Het |
| Spns3 |
C |
A |
11: 72,428,027 (GRCm39) |
W251L |
probably damaging |
Het |
| Spta1 |
A |
G |
1: 174,067,789 (GRCm39) |
N2072S |
possibly damaging |
Het |
| Sptbn1 |
A |
G |
11: 30,074,016 (GRCm39) |
V1351A |
probably benign |
Het |
| Sytl2 |
A |
T |
7: 90,030,523 (GRCm39) |
|
probably benign |
Het |
| Tax1bp1 |
A |
G |
6: 52,706,478 (GRCm39) |
|
probably benign |
Het |
| Tg |
A |
G |
15: 66,568,435 (GRCm39) |
D1374G |
probably benign |
Het |
| Tlr1 |
A |
G |
5: 65,083,567 (GRCm39) |
S337P |
probably damaging |
Het |
| Trp63 |
A |
T |
16: 25,686,977 (GRCm39) |
D303V |
probably damaging |
Het |
| Ttn |
G |
A |
2: 76,683,250 (GRCm39) |
|
probably benign |
Het |
| Txndc5 |
T |
C |
13: 38,712,160 (GRCm39) |
|
probably null |
Het |
| Vmn2r77 |
T |
G |
7: 86,451,015 (GRCm39) |
D300E |
possibly damaging |
Het |
| Zfp729a |
A |
T |
13: 67,768,365 (GRCm39) |
N621K |
probably benign |
Het |
|
| Other mutations in Nisch |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01782:Nisch
|
APN |
14 |
30,898,596 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01934:Nisch
|
APN |
14 |
30,898,696 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02201:Nisch
|
APN |
14 |
30,909,051 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02964:Nisch
|
APN |
14 |
30,902,769 (GRCm39) |
unclassified |
probably benign |
|
|
IGL03340:Nisch
|
APN |
14 |
30,895,101 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R0092:Nisch
|
UTSW |
14 |
30,913,410 (GRCm39) |
unclassified |
probably benign |
|
|
R0119:Nisch
|
UTSW |
14 |
30,893,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0196:Nisch
|
UTSW |
14 |
30,925,351 (GRCm39) |
unclassified |
probably benign |
|
|
R0299:Nisch
|
UTSW |
14 |
30,893,881 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0452:Nisch
|
UTSW |
14 |
30,899,421 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R1529:Nisch
|
UTSW |
14 |
30,902,895 (GRCm39) |
unclassified |
probably benign |
|
|
R1643:Nisch
|
UTSW |
14 |
30,895,125 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1656:Nisch
|
UTSW |
14 |
30,899,228 (GRCm39) |
unclassified |
probably benign |
|
|
R1663:Nisch
|
UTSW |
14 |
30,913,478 (GRCm39) |
unclassified |
probably benign |
|
|
R1676:Nisch
|
UTSW |
14 |
30,902,859 (GRCm39) |
unclassified |
probably benign |
|
|
R1750:Nisch
|
UTSW |
14 |
30,896,839 (GRCm39) |
unclassified |
probably benign |
|
|
R1799:Nisch
|
UTSW |
14 |
30,899,228 (GRCm39) |
unclassified |
probably benign |
|
|
R1824:Nisch
|
UTSW |
14 |
30,898,389 (GRCm39) |
unclassified |
probably benign |
|
|
R1876:Nisch
|
UTSW |
14 |
30,895,594 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2107:Nisch
|
UTSW |
14 |
30,894,097 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2117:Nisch
|
UTSW |
14 |
30,899,242 (GRCm39) |
unclassified |
probably benign |
|
|
R2276:Nisch
|
UTSW |
14 |
30,898,803 (GRCm39) |
unclassified |
probably benign |
|
|
R2402:Nisch
|
UTSW |
14 |
30,906,971 (GRCm39) |
intron |
probably benign |
|
|
R3703:Nisch
|
UTSW |
14 |
30,898,702 (GRCm39) |
unclassified |
probably benign |
|
|
R3704:Nisch
|
UTSW |
14 |
30,898,702 (GRCm39) |
unclassified |
probably benign |
|
|
R3705:Nisch
|
UTSW |
14 |
30,898,702 (GRCm39) |
unclassified |
probably benign |
|
|
R3897:Nisch
|
UTSW |
14 |
30,912,957 (GRCm39) |
unclassified |
probably benign |
|
|
R4024:Nisch
|
UTSW |
14 |
30,898,776 (GRCm39) |
unclassified |
probably benign |
|
|
R4412:Nisch
|
UTSW |
14 |
30,908,615 (GRCm39) |
intron |
probably benign |
|
|
R4752:Nisch
|
UTSW |
14 |
30,914,545 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4832:Nisch
|
UTSW |
14 |
30,899,587 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R5043:Nisch
|
UTSW |
14 |
30,898,422 (GRCm39) |
unclassified |
probably benign |
|
|
R5062:Nisch
|
UTSW |
14 |
30,894,397 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5254:Nisch
|
UTSW |
14 |
30,928,524 (GRCm39) |
splice site |
probably null |
|
|
R5754:Nisch
|
UTSW |
14 |
30,913,373 (GRCm39) |
unclassified |
probably benign |
|
|
R5906:Nisch
|
UTSW |
14 |
30,893,985 (GRCm39) |
splice site |
probably null |
|
|
R5930:Nisch
|
UTSW |
14 |
30,895,102 (GRCm39) |
missense |
probably benign |
0.11 |
|
R6246:Nisch
|
UTSW |
14 |
30,894,516 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6258:Nisch
|
UTSW |
14 |
30,899,085 (GRCm39) |
unclassified |
probably benign |
|
|
R6260:Nisch
|
UTSW |
14 |
30,899,085 (GRCm39) |
unclassified |
probably benign |
|
|
R6327:Nisch
|
UTSW |
14 |
30,893,444 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R6671:Nisch
|
UTSW |
14 |
30,926,420 (GRCm39) |
unclassified |
probably benign |
|
|
R6874:Nisch
|
UTSW |
14 |
30,898,641 (GRCm39) |
unclassified |
probably benign |
|
|
R6887:Nisch
|
UTSW |
14 |
30,907,301 (GRCm39) |
unclassified |
probably benign |
|
|
R7273:Nisch
|
UTSW |
14 |
30,896,364 (GRCm39) |
missense |
unknown |
|
|
R7401:Nisch
|
UTSW |
14 |
30,928,537 (GRCm39) |
missense |
probably benign |
0.18 |
|
R7423:Nisch
|
UTSW |
14 |
30,893,658 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7822:Nisch
|
UTSW |
14 |
30,896,608 (GRCm39) |
unclassified |
probably benign |
|
|
R7870:Nisch
|
UTSW |
14 |
30,894,052 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7887:Nisch
|
UTSW |
14 |
30,898,652 (GRCm39) |
nonsense |
probably null |
|
|
R8215:Nisch
|
UTSW |
14 |
30,908,658 (GRCm39) |
missense |
possibly damaging |
0.59 |
|
R8672:Nisch
|
UTSW |
14 |
30,895,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9082:Nisch
|
UTSW |
14 |
30,899,331 (GRCm39) |
missense |
unknown |
|
|
R9134:Nisch
|
UTSW |
14 |
30,896,637 (GRCm39) |
unclassified |
probably benign |
|
|
R9153:Nisch
|
UTSW |
14 |
30,896,782 (GRCm39) |
missense |
unknown |
|
|
R9240:Nisch
|
UTSW |
14 |
30,906,988 (GRCm39) |
missense |
unknown |
|
|
R9652:Nisch
|
UTSW |
14 |
30,893,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9653:Nisch
|
UTSW |
14 |
30,893,628 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9663:Nisch
|
UTSW |
14 |
30,895,625 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9667:Nisch
|
UTSW |
14 |
30,895,646 (GRCm39) |
missense |
probably damaging |
1.00 |
|
X0027:Nisch
|
UTSW |
14 |
30,909,041 (GRCm39) |
unclassified |
probably benign |
|
|
Z1177:Nisch
|
UTSW |
14 |
30,899,395 (GRCm39) |
frame shift |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GCTTACCTGCTCAATCCGGTTG -3'
(R):5'- AGGCAGATCTTCAGTGCTCAC -3'
Sequencing Primer
(F):5'- TGTCTCGTAGGTCCACATTAACCAAG -3'
(R):5'- ATGCCAGCAGGTTATATCATGG -3'
|
| Posted On |
2016-06-06 |
Incidental Mutation