Mutagenetix > Incidental Mutation

Incidental Mutation 'R5119:Prrc2c'

392775

Institutional Source

Beutler Lab

Gene Symbol

Prrc2c

Ensembl Gene

ENSMUSG00000040225

Gene Name

proline-rich coiled-coil 2C

Synonyms

9630039I18Rik, Bat2d, 1810043M20Rik, Bat2l2

MMRRC Submission

042707-MU

Accession Numbers

Essential gene?

Possibly non essential (E-score: 0.410) question?

Stock #

R5119 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

162499354-162568125 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

T to C at 162533009 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000138698 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000028016] [ENSMUST00000182149] [ENSMUST00000182393] [ENSMUST00000182593] [ENSMUST00000182660] [ENSMUST00000183011] [ENSMUST00000183223]

AlphaFold

no structure available at present

Predicted Effect

unknown
Transcript: ENSMUST00000028016
AA Change: E1200G

SMART Domains

Protein: ENSMUSP00000028016
Gene: ENSMUSG00000040225
AA Change: E1200G

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	164	7.7e-56	PFAM
internal_repeat_2	167	349	4.39e-5	PROSPERO
internal_repeat_1	336	391	2.14e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	2.14e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	4.39e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC
low complexity region	2811	2828	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000182149
AA Change: E1202G

SMART Domains

Protein: ENSMUSP00000138548
Gene: ENSMUSG00000040225
AA Change: E1202G

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	167	5.6e-73	PFAM
internal_repeat_1	336	391	1.49e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
internal_repeat_3	754	925	9.16e-5	PROSPERO
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	1.49e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	3.08e-5	PROSPERO
internal_repeat_3	1983	2153	9.16e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000182393

SMART Domains

Protein: ENSMUSP00000138451
Gene: ENSMUSG00000040225

Domain	Start	End	E-Value	Type
low complexity region	24	51	N/A	INTRINSIC
low complexity region	104	125	N/A	INTRINSIC
low complexity region	431	462	N/A	INTRINSIC
low complexity region	481	519	N/A	INTRINSIC
low complexity region	531	548	N/A	INTRINSIC
low complexity region	560	625	N/A	INTRINSIC
low complexity region	879	893	N/A	INTRINSIC
low complexity region	946	968	N/A	INTRINSIC
low complexity region	988	1002	N/A	INTRINSIC
low complexity region	1037	1054	N/A	INTRINSIC
low complexity region	1143	1154	N/A	INTRINSIC
low complexity region	1274	1297	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000182593
AA Change: E1200G

SMART Domains

Protein: ENSMUSP00000138674
Gene: ENSMUSG00000040225
AA Change: E1200G

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	165	4.1e-70	PFAM
internal_repeat_1	334	389	9.57e-6	PROSPERO
low complexity region	405	412	N/A	INTRINSIC
SCOP:d1eq1a_	445	589	3e-5	SMART
low complexity region	647	667	N/A	INTRINSIC
low complexity region	731	743	N/A	INTRINSIC
internal_repeat_3	752	923	6.11e-5	PROSPERO
coiled coil region	994	1024	N/A	INTRINSIC
low complexity region	1155	1184	N/A	INTRINSIC
low complexity region	1210	1220	N/A	INTRINSIC
internal_repeat_1	1238	1293	9.57e-6	PROSPERO
low complexity region	1306	1333	N/A	INTRINSIC
low complexity region	1386	1407	N/A	INTRINSIC
low complexity region	1713	1744	N/A	INTRINSIC
low complexity region	1763	1801	N/A	INTRINSIC
low complexity region	1813	1830	N/A	INTRINSIC
low complexity region	1842	1907	N/A	INTRINSIC
internal_repeat_2	1960	2146	2.01e-5	PROSPERO
internal_repeat_3	1981	2151	6.11e-5	PROSPERO
low complexity region	2161	2175	N/A	INTRINSIC
low complexity region	2228	2250	N/A	INTRINSIC
low complexity region	2270	2284	N/A	INTRINSIC
low complexity region	2319	2336	N/A	INTRINSIC
low complexity region	2425	2436	N/A	INTRINSIC
low complexity region	2551	2574	N/A	INTRINSIC
low complexity region	2671	2682	N/A	INTRINSIC
low complexity region	2730	2747	N/A	INTRINSIC

Predicted Effect

unknown
Transcript: ENSMUST00000182660
AA Change: E1202G

SMART Domains

Protein: ENSMUSP00000138433
Gene: ENSMUSG00000040225
AA Change: E1202G

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	167	7e-73	PFAM
internal_repeat_1	336	391	2.14e-5	PROSPERO
low complexity region	407	414	N/A	INTRINSIC
SCOP:d1eq1a_	447	591	2e-5	SMART
low complexity region	649	669	N/A	INTRINSIC
low complexity region	733	745	N/A	INTRINSIC
coiled coil region	996	1026	N/A	INTRINSIC
low complexity region	1157	1186	N/A	INTRINSIC
low complexity region	1212	1222	N/A	INTRINSIC
internal_repeat_1	1240	1295	2.14e-5	PROSPERO
low complexity region	1308	1335	N/A	INTRINSIC
low complexity region	1388	1409	N/A	INTRINSIC
low complexity region	1715	1746	N/A	INTRINSIC
low complexity region	1765	1803	N/A	INTRINSIC
low complexity region	1815	1832	N/A	INTRINSIC
low complexity region	1844	1909	N/A	INTRINSIC
internal_repeat_2	1962	2148	4.39e-5	PROSPERO
low complexity region	2163	2177	N/A	INTRINSIC
low complexity region	2230	2252	N/A	INTRINSIC
low complexity region	2272	2286	N/A	INTRINSIC
low complexity region	2321	2338	N/A	INTRINSIC
low complexity region	2427	2438	N/A	INTRINSIC
low complexity region	2553	2576	N/A	INTRINSIC
low complexity region	2811	2828	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000183011

SMART Domains

Protein: ENSMUSP00000138609
Gene: ENSMUSG00000040225

Domain	Start	End	E-Value	Type
Pfam:BAT2_N	1	160	3.2e-64	PFAM
low complexity region	400	407	N/A	INTRINSIC
coiled coil region	443	560	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000183223

SMART Domains

Protein: ENSMUSP00000138698
Gene: ENSMUSG00000040225

Domain	Start	End	E-Value	Type
low complexity region	289	320	N/A	INTRINSIC
low complexity region	339	377	N/A	INTRINSIC
low complexity region	389	406	N/A	INTRINSIC
low complexity region	418	483	N/A	INTRINSIC
low complexity region	739	761	N/A	INTRINSIC
low complexity region	781	795	N/A	INTRINSIC
low complexity region	830	847	N/A	INTRINSIC
low complexity region	936	947	N/A	INTRINSIC
low complexity region	1062	1085	N/A	INTRINSIC
low complexity region	1182	1193	N/A	INTRINSIC
low complexity region	1241	1258	N/A	INTRINSIC

Meta Mutation Damage Score

0.0987

Coding Region Coverage

1x: 99.2%
3x: 98.5%
10x: 96.8%
20x: 94.1%

Validation Efficiency

100% (127/127)

Allele List at MGI

Other mutations in this stock

Total: 120 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
4930470P17Rik	C	A	2: 170,421,505 (GRCm39)	G125V	unknown	Het
Actr6	A	T	10: 89,561,717 (GRCm39)	L143Q	probably damaging	Het
Adamts18	A	G	8: 114,425,642 (GRCm39)	Y1207H	probably benign	Het
Adamts5	T	A	16: 85,696,466 (GRCm39)	R230S	probably benign	Het
Adat2	A	T	10: 13,432,650 (GRCm39)	N51Y	probably damaging	Het
Adgrv1	T	C	13: 81,567,546 (GRCm39)	Y5209C	possibly damaging	Het
Ahnak	G	T	19: 8,991,008 (GRCm39)	M4097I	probably benign	Het
Akap13	A	G	7: 75,337,000 (GRCm39)	T820A	probably damaging	Het
Als2cl	C	T	9: 110,719,887 (GRCm39)	R492C	probably damaging	Het
Aox3	G	A	1: 58,227,683 (GRCm39)		probably null	Het
Arid4b	G	A	13: 14,338,866 (GRCm39)	V446M	probably benign	Het
Armc2	A	G	10: 41,798,144 (GRCm39)	L794P	probably damaging	Het
Atp6v0a1	T	A	11: 100,911,341 (GRCm39)	M80K	probably benign	Het
Aup1	T	C	6: 83,032,115 (GRCm39)	V94A	probably damaging	Het
Bank1	A	T	3: 135,940,443 (GRCm39)	I180K	possibly damaging	Het
Becn1	A	G	11: 101,182,221 (GRCm39)	L116P	probably damaging	Het
Bsg	A	G	10: 79,546,057 (GRCm39)		probably benign	Het
Camk2a	A	T	18: 61,076,208 (GRCm39)		probably benign	Het
Ccdc180	A	G	4: 45,914,603 (GRCm39)	E706G	possibly damaging	Het
Cdk8	A	T	5: 146,220,437 (GRCm39)		probably null	Het
Cpne4	A	G	9: 104,778,720 (GRCm39)		probably null	Het
Cspp1	T	A	1: 10,196,688 (GRCm39)	N900K	probably damaging	Het
Cyp2c38	C	A	19: 39,449,065 (GRCm39)	G96V	probably damaging	Het
Dhx40	A	G	11: 86,667,462 (GRCm39)	I261T	probably damaging	Het
Dnah10	T	C	5: 124,856,322 (GRCm39)	F2038L	probably damaging	Het
Dnah7a	A	T	1: 53,737,851 (GRCm39)	D27E	probably benign	Het
Dock10	A	T	1: 80,545,711 (GRCm39)		probably null	Het
Dst	A	T	1: 34,235,050 (GRCm39)	K3710*	probably null	Het
Dtl	G	T	1: 191,273,618 (GRCm39)	A430D	probably damaging	Het
Ece2	T	C	16: 20,437,381 (GRCm39)	L241P	probably damaging	Het
Ecel1	T	A	1: 87,078,861 (GRCm39)	Y526F	probably benign	Het
Enpp2	T	A	15: 54,733,701 (GRCm39)	R420*	probably null	Het
Epb41	A	C	4: 131,664,747 (GRCm39)		probably benign	Het
Eppin	T	C	2: 164,431,371 (GRCm39)	Y85C	probably damaging	Het
Fam171a2	G	A	11: 102,329,559 (GRCm39)	A400V	probably damaging	Het
Fem1c	A	C	18: 46,639,436 (GRCm39)	C189G	probably damaging	Het
Frmd4b	A	G	6: 97,277,275 (GRCm39)	V560A	probably benign	Het
Fsip2	A	T	2: 82,818,535 (GRCm39)	D4756V	probably damaging	Het
Gabbr1	T	C	17: 37,359,330 (GRCm39)	S102P	probably damaging	Het
Garin3	G	A	11: 46,297,863 (GRCm39)	G389D	probably damaging	Het
Gm28042	G	A	2: 119,865,124 (GRCm39)	A250T	probably damaging	Het
Gm30275	T	C	14: 54,312,978 (GRCm39)		probably benign	Het
Gm9762	A	T	3: 78,873,707 (GRCm39)		noncoding transcript	Het
Gpr183	G	T	14: 122,192,275 (GRCm39)	T82N	possibly damaging	Het
Gps2	A	G	11: 69,805,617 (GRCm39)	K45R	probably benign	Het
Gramd2a	A	G	9: 59,621,603 (GRCm39)		probably benign	Het
Grap2	G	A	15: 80,530,345 (GRCm39)	R155Q	possibly damaging	Het
Hsdl1	T	A	8: 120,292,606 (GRCm39)	Y203F	possibly damaging	Het
Ifi204	A	T	1: 173,583,234 (GRCm39)	I328N	probably damaging	Het
Igsf3	T	A	3: 101,346,677 (GRCm39)		probably null	Het
Il1rap	T	C	16: 26,442,949 (GRCm39)	I15T	probably benign	Het
Il23r	A	T	6: 67,443,300 (GRCm39)	C268S	probably damaging	Het
Irx4	A	G	13: 73,417,040 (GRCm39)	T479A	probably benign	Het
Kcnk7	G	A	19: 5,756,352 (GRCm39)	V193I	probably benign	Het
Kcnt1	G	T	2: 25,799,334 (GRCm39)		probably benign	Het
Kif13b	T	G	14: 64,994,902 (GRCm39)	C885G	probably benign	Het
Kif21b	C	A	1: 136,090,838 (GRCm39)	D1215E	probably benign	Het
Klhdc2	A	G	12: 69,343,736 (GRCm39)		probably benign	Het
Kmt2d	G	A	15: 98,745,075 (GRCm39)		probably benign	Het
Lama4	A	G	10: 38,924,050 (GRCm39)	N486S	probably benign	Het
Ldah	G	A	12: 8,277,237 (GRCm39)	A58T	probably benign	Het
Lrrc24	T	C	15: 76,600,200 (GRCm39)	Q313R	probably benign	Het
Luzp1	A	G	4: 136,270,708 (GRCm39)	D977G	possibly damaging	Het
Meak7	A	C	8: 120,494,882 (GRCm39)	L292R	probably damaging	Het
Mrgpra4	A	G	7: 47,631,466 (GRCm39)	L45P	probably damaging	Het
Mrps28	C	T	3: 8,988,756 (GRCm39)	G34D	possibly damaging	Het
Myh8	A	G	11: 67,189,184 (GRCm39)	E1120G	probably damaging	Het
Myt1l	A	G	12: 29,882,302 (GRCm39)	E499G	unknown	Het
Ncan	C	T	8: 70,567,675 (GRCm39)	E146K	probably damaging	Het
Nlgn1	A	T	3: 25,487,958 (GRCm39)	D763E	probably damaging	Het
Or11g26	T	C	14: 50,752,966 (GRCm39)	F102L	probably benign	Het
Or13c7c	G	T	4: 43,836,433 (GRCm39)	A19D	probably benign	Het
Or1e17	A	T	11: 73,831,378 (GRCm39)	Y102F	possibly damaging	Het
Or4c12	A	T	2: 89,774,147 (GRCm39)	I104N	possibly damaging	Het
Or5b118	C	T	19: 13,448,910 (GRCm39)	T192I	probably benign	Het
Or6c8b	T	A	10: 128,882,711 (GRCm39)	I74F	possibly damaging	Het
Pak6	A	T	2: 118,525,029 (GRCm39)	I552F	probably damaging	Het
Pcbp1	G	A	6: 86,501,897 (GRCm39)	A334V	probably damaging	Het
Pclaf	T	C	9: 65,798,062 (GRCm39)	V32A	probably benign	Het
Pga5	T	A	19: 10,654,053 (GRCm39)	H50L	probably benign	Het
Phyhipl	A	T	10: 70,404,904 (GRCm39)	D56E	probably damaging	Het
Pik3ap1	C	T	19: 41,270,415 (GRCm39)	R758H	probably benign	Het
Plekha1	A	G	7: 130,507,094 (GRCm39)		probably benign	Het
Plekhm1	A	T	11: 103,278,141 (GRCm39)	N318K	possibly damaging	Het
Ppargc1b	G	A	18: 61,440,725 (GRCm39)	A731V	probably benign	Het
Pptc7	T	C	5: 122,451,844 (GRCm39)	V100A	possibly damaging	Het
Prl7a1	A	T	13: 27,817,564 (GRCm39)	H233Q	possibly damaging	Het
Prpf40a	A	G	2: 53,034,861 (GRCm39)	F776L	probably damaging	Het
Psmb1	T	C	17: 15,718,524 (GRCm39)	M1V	probably null	Het
Ptpn3	A	G	4: 57,218,513 (GRCm39)	F650S	possibly damaging	Het
Ranbp17	A	T	11: 33,354,181 (GRCm39)	*577R	probably null	Het
Reln	T	A	5: 22,176,868 (GRCm39)	N1933Y	probably benign	Het
Rgl2	T	A	17: 34,156,094 (GRCm39)	H727Q	probably benign	Het
Rhpn2	A	G	7: 35,070,549 (GRCm39)	T160A	probably damaging	Het
Rlf	G	A	4: 121,004,652 (GRCm39)	H1443Y	probably damaging	Het
Rpgrip1l	T	C	8: 92,007,444 (GRCm39)	E382G	probably damaging	Het
Rxrb	T	C	17: 34,252,562 (GRCm39)	S50P	probably benign	Het
Scn4b	A	T	9: 45,059,056 (GRCm39)	E109V	probably damaging	Het
Scrib	C	T	15: 75,923,602 (GRCm39)		probably null	Het
Slc22a29	A	T	19: 8,195,194 (GRCm39)	V147D	probably damaging	Het
Slc4a4	A	T	5: 89,102,721 (GRCm39)	E53V	probably null	Het
Slx4	A	G	16: 3,819,063 (GRCm39)	S37P	possibly damaging	Het
Spag9	G	A	11: 94,013,548 (GRCm39)	G1127D	probably damaging	Het
Srek1	T	A	13: 103,889,064 (GRCm39)		probably benign	Het
Supt5	G	T	7: 28,015,795 (GRCm39)	P849Q	probably damaging	Het
Tex14	T	C	11: 87,324,639 (GRCm39)	S2P	probably damaging	Het
Them7	A	G	2: 105,209,153 (GRCm39)	T158A	probably benign	Het
Tll2	A	G	19: 41,118,948 (GRCm39)	V260A	possibly damaging	Het
Tlr6	A	G	5: 65,111,644 (GRCm39)	V421A	probably benign	Het
Tmc3	T	G	7: 83,264,218 (GRCm39)	C649G	probably damaging	Het
Tnn	A	G	1: 159,948,122 (GRCm39)	W864R	probably damaging	Het
Tsc2	A	C	17: 24,822,254 (GRCm39)	V1095G	probably benign	Het
Vmn1r124	C	T	7: 20,994,172 (GRCm39)	G124D	probably damaging	Het
Vmn2r116	T	C	17: 23,606,138 (GRCm39)	V350A	probably benign	Het
Vps13d	A	G	4: 144,832,468 (GRCm39)	S2813P	possibly damaging	Het
Wrap53	T	A	11: 69,454,758 (GRCm39)	M204L	possibly damaging	Het
Zfp277	A	G	12: 40,378,687 (GRCm39)	V390A	possibly damaging	Het
Zfp687	A	T	3: 94,918,987 (GRCm39)	S262T	probably benign	Het
Zfp831	T	A	2: 174,547,103 (GRCm39)	S1429T	probably benign	Het
Znfx1	G	A	2: 166,907,307 (GRCm39)		probably benign	Het

Other mutations in Prrc2c

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00425:Prrc2c	APN	1	162,548,182 (GRCm39)	splice site	probably null
IGL00577:Prrc2c	APN	1	162,525,685 (GRCm39)	missense	unknown
IGL00580:Prrc2c	APN	1	162,525,685 (GRCm39)	missense	unknown
IGL01295:Prrc2c	APN	1	162,510,061 (GRCm39)	missense	probably damaging	1.00
IGL01554:Prrc2c	APN	1	162,538,355 (GRCm39)	missense	probably damaging	0.99
IGL01684:Prrc2c	APN	1	162,534,031 (GRCm39)	unclassified	probably benign
IGL01745:Prrc2c	APN	1	162,552,297 (GRCm39)	missense	probably damaging	1.00
IGL01770:Prrc2c	APN	1	162,532,068 (GRCm39)	missense	probably benign	0.23
IGL01905:Prrc2c	APN	1	162,532,898 (GRCm39)	unclassified	probably benign
IGL02304:Prrc2c	APN	1	162,511,705 (GRCm39)	missense	probably benign	0.05
IGL02389:Prrc2c	APN	1	162,520,439 (GRCm39)	missense	probably damaging	1.00
IGL02540:Prrc2c	APN	1	162,550,706 (GRCm39)	missense	probably damaging	1.00
IGL02681:Prrc2c	APN	1	162,533,181 (GRCm39)	unclassified	probably benign
IGL02686:Prrc2c	APN	1	162,535,516 (GRCm39)	unclassified	probably benign
IGL02795:Prrc2c	APN	1	162,541,868 (GRCm39)	missense	probably benign
IGL02894:Prrc2c	APN	1	162,505,626 (GRCm39)	missense	probably damaging	1.00
IGL02957:Prrc2c	APN	1	162,534,104 (GRCm39)	unclassified	probably benign
IGL02981:Prrc2c	APN	1	162,532,748 (GRCm39)	unclassified	probably benign
IGL03070:Prrc2c	APN	1	162,504,978 (GRCm39)	missense	probably damaging	1.00
IGL03096:Prrc2c	APN	1	162,529,928 (GRCm39)	missense	unknown
R0058:Prrc2c	UTSW	1	162,526,453 (GRCm39)	missense	unknown
R0058:Prrc2c	UTSW	1	162,526,453 (GRCm39)	missense	unknown
R0135:Prrc2c	UTSW	1	162,543,052 (GRCm39)	splice site	probably benign
R0279:Prrc2c	UTSW	1	162,543,033 (GRCm39)	missense	probably damaging	1.00
R0363:Prrc2c	UTSW	1	162,525,380 (GRCm39)	missense	unknown
R0436:Prrc2c	UTSW	1	162,532,883 (GRCm39)	unclassified	probably benign
R0605:Prrc2c	UTSW	1	162,509,995 (GRCm39)	missense	probably damaging	1.00
R0696:Prrc2c	UTSW	1	162,536,421 (GRCm39)	critical splice donor site	probably null
R0981:Prrc2c	UTSW	1	162,533,550 (GRCm39)	unclassified	probably benign
R1693:Prrc2c	UTSW	1	162,546,282 (GRCm39)	missense	probably damaging	0.98
R1714:Prrc2c	UTSW	1	162,504,945 (GRCm39)	missense	probably damaging	1.00
R1791:Prrc2c	UTSW	1	162,532,551 (GRCm39)	unclassified	probably benign
R1794:Prrc2c	UTSW	1	162,533,528 (GRCm39)	unclassified	probably benign
R1998:Prrc2c	UTSW	1	162,532,487 (GRCm39)	unclassified	probably benign
R2040:Prrc2c	UTSW	1	162,525,126 (GRCm39)	missense	probably damaging	1.00
R2168:Prrc2c	UTSW	1	162,537,903 (GRCm39)	unclassified	probably benign
R2246:Prrc2c	UTSW	1	162,535,360 (GRCm39)	unclassified	probably benign
R2830:Prrc2c	UTSW	1	162,536,485 (GRCm39)	unclassified	probably benign
R2926:Prrc2c	UTSW	1	162,533,696 (GRCm39)	unclassified	probably benign
R3703:Prrc2c	UTSW	1	162,538,260 (GRCm39)	missense	probably damaging	1.00
R3745:Prrc2c	UTSW	1	162,525,754 (GRCm39)	missense	unknown
R3760:Prrc2c	UTSW	1	162,520,420 (GRCm39)	missense	probably damaging	1.00
R3784:Prrc2c	UTSW	1	162,537,238 (GRCm39)	unclassified	probably benign
R3959:Prrc2c	UTSW	1	162,536,461 (GRCm39)	unclassified	probably benign
R4255:Prrc2c	UTSW	1	162,533,895 (GRCm39)	unclassified	probably benign
R4276:Prrc2c	UTSW	1	162,501,160 (GRCm39)	missense	probably damaging	1.00
R4421:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R4593:Prrc2c	UTSW	1	162,525,101 (GRCm39)	missense	probably damaging	1.00
R4651:Prrc2c	UTSW	1	162,550,843 (GRCm39)	missense	probably damaging	1.00
R4652:Prrc2c	UTSW	1	162,550,843 (GRCm39)	missense	probably damaging	1.00
R4660:Prrc2c	UTSW	1	162,508,464 (GRCm39)	missense	probably damaging	1.00
R4677:Prrc2c	UTSW	1	162,532,748 (GRCm39)	unclassified	probably benign
R4688:Prrc2c	UTSW	1	162,525,256 (GRCm39)	missense	unknown
R4753:Prrc2c	UTSW	1	162,518,799 (GRCm39)	missense	probably damaging	1.00
R4790:Prrc2c	UTSW	1	162,538,050 (GRCm39)	missense	unknown
R4981:Prrc2c	UTSW	1	162,520,116 (GRCm39)	missense	probably damaging	1.00
R4995:Prrc2c	UTSW	1	162,532,879 (GRCm39)	unclassified	probably benign
R5127:Prrc2c	UTSW	1	162,525,415 (GRCm39)	missense	unknown
R5291:Prrc2c	UTSW	1	162,533,151 (GRCm39)	unclassified	probably benign
R5474:Prrc2c	UTSW	1	162,537,213 (GRCm39)	unclassified	probably benign
R5543:Prrc2c	UTSW	1	162,501,080 (GRCm39)	missense	probably damaging	0.99
R5579:Prrc2c	UTSW	1	162,508,327 (GRCm39)	critical splice donor site	probably null
R5594:Prrc2c	UTSW	1	162,526,600 (GRCm39)	missense	unknown
R5620:Prrc2c	UTSW	1	162,501,098 (GRCm39)	missense	probably damaging	1.00
R5994:Prrc2c	UTSW	1	162,501,725 (GRCm39)	splice site	probably null
R6142:Prrc2c	UTSW	1	162,537,956 (GRCm39)	missense	unknown
R6199:Prrc2c	UTSW	1	162,510,085 (GRCm39)	missense	probably damaging	1.00
R6277:Prrc2c	UTSW	1	162,541,883 (GRCm39)	missense	probably benign
R6504:Prrc2c	UTSW	1	162,525,364 (GRCm39)	missense	unknown
R6671:Prrc2c	UTSW	1	162,525,154 (GRCm39)	missense	probably damaging	1.00
R6785:Prrc2c	UTSW	1	162,536,670 (GRCm39)	unclassified	probably benign
R6799:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6801:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6850:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6851:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6856:Prrc2c	UTSW	1	162,509,940 (GRCm39)	missense	probably damaging	1.00
R6869:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6882:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6884:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R6897:Prrc2c	UTSW	1	162,533,075 (GRCm39)	unclassified	probably benign
R6934:Prrc2c	UTSW	1	162,548,074 (GRCm39)	missense	probably benign	0.10
R6976:Prrc2c	UTSW	1	162,520,413 (GRCm39)	missense	probably damaging	1.00
R7132:Prrc2c	UTSW	1	162,508,850 (GRCm39)	missense	possibly damaging	0.77
R7165:Prrc2c	UTSW	1	162,501,086 (GRCm39)	missense	possibly damaging	0.94
R7282:Prrc2c	UTSW	1	162,507,543 (GRCm39)	missense	possibly damaging	0.59
R7467:Prrc2c	UTSW	1	162,504,932 (GRCm39)	missense	possibly damaging	0.84
R7915:Prrc2c	UTSW	1	162,519,977 (GRCm39)	missense	probably benign	0.39
R8068:Prrc2c	UTSW	1	162,536,630 (GRCm39)	unclassified	probably benign
R8529:Prrc2c	UTSW	1	162,536,663 (GRCm39)	unclassified	probably benign
R8734:Prrc2c	UTSW	1	162,507,081 (GRCm39)	missense	possibly damaging	0.92
R8735:Prrc2c	UTSW	1	162,537,127 (GRCm39)	missense	unknown
R8813:Prrc2c	UTSW	1	162,532,812 (GRCm39)	missense	unknown
R8946:Prrc2c	UTSW	1	162,536,478 (GRCm39)	unclassified	probably benign
R8975:Prrc2c	UTSW	1	162,533,630 (GRCm39)	missense	unknown
R9035:Prrc2c	UTSW	1	162,503,295 (GRCm39)	missense	possibly damaging	0.96
R9185:Prrc2c	UTSW	1	162,532,212 (GRCm39)	missense	unknown
R9261:Prrc2c	UTSW	1	162,505,622 (GRCm39)	missense	possibly damaging	0.48
R9287:Prrc2c	UTSW	1	162,541,843 (GRCm39)	missense	probably benign	0.34
R9289:Prrc2c	UTSW	1	162,507,130 (GRCm39)	missense	probably benign	0.33
R9466:Prrc2c	UTSW	1	162,503,258 (GRCm39)	missense	possibly damaging	0.53
R9523:Prrc2c	UTSW	1	162,525,298 (GRCm39)	missense	unknown
R9542:Prrc2c	UTSW	1	162,508,359 (GRCm39)	missense	possibly damaging	0.88
R9629:Prrc2c	UTSW	1	162,519,959 (GRCm39)	missense	possibly damaging	0.95
R9744:Prrc2c	UTSW	1	162,505,733 (GRCm39)	missense	possibly damaging	0.96
R9748:Prrc2c	UTSW	1	162,535,435 (GRCm39)	missense	unknown
X0020:Prrc2c	UTSW	1	162,535,416 (GRCm39)	unclassified	probably benign
X0039:Prrc2c	UTSW	1	162,532,362 (GRCm39)	frame shift	probably null

Predicted Primers

PCR Primer
(F):5'- GGAAGTTTCCCTTTGCTTACACTG -3'
(R):5'- CGCCCAGATTCTAGACTAGCAG -3'

Sequencing Primer
(F):5'- ACACTGTCTTTGTCACTCGCAC -3'
(R):5'- GCCCAGATTCTAGACTAGCAGTTAAG -3'

Posted On

2016-06-15