Mutagenetix > Incidental Mutation

Incidental Mutation 'R5145:Gm38706'

395081

Institutional Source

Beutler Lab

Gene Symbol

Gm38706

Ensembl Gene

Gene Name

predicted gene, 38706

Synonyms

MMRRC Submission

042729-MU

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.207) question?

Stock #

R5145 (G1)

Quality Score

225

Status

Validated

Chromosome

Chromosomal Location

130554505-130556654 bp(-) (GRCm39)

Type of Mutation

exon

DNA Base Change (assembly)

G to A at 130460731 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Gene Model

predicted gene model for transcript(s):

AlphaFold

no structure available at present

Predicted Effect

noncoding transcript
Transcript: ENSMUST00000182397

Meta Mutation Damage Score

0.0869

Coding Region Coverage

1x: 99.3%
3x: 98.6%
10x: 97.2%
20x: 94.8%

Validation Efficiency

100% (37/37)

Allele List at MGI

Other mutations in this stock

Total: 32 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Adamts12	G	A	15: 11,285,962 (GRCm39)	G724R	probably damaging	Het
Adgrg7	T	A	16: 56,562,682 (GRCm39)	I552L	probably benign	Het
Ankrd11	A	G	8: 123,617,943 (GRCm39)		probably benign	Het
Col12a1	T	C	9: 79,613,582 (GRCm39)	T88A	probably benign	Het
Col6a5	T	G	9: 105,811,444 (GRCm39)	I692L	unknown	Het
Cry2	T	C	2: 92,243,405 (GRCm39)	I479V	probably benign	Het
Ddx21	T	C	10: 62,423,318 (GRCm39)		probably null	Het
Efcab12	T	A	6: 115,800,238 (GRCm39)	I262F	probably damaging	Het
Eif2ak2	T	C	17: 79,183,633 (GRCm39)	D72G	possibly damaging	Het
Fry	T	C	5: 150,293,689 (GRCm39)	F461L	probably damaging	Het
Gm9772	C	T	17: 22,226,107 (GRCm39)	C59Y	probably damaging	Het
Meig1	T	C	2: 3,410,263 (GRCm39)	E79G	probably damaging	Het
Mfng	C	T	15: 78,648,588 (GRCm39)	R163H	probably benign	Het
Mfsd2b	T	A	12: 4,915,908 (GRCm39)		probably benign	Het
Nfatc2	A	C	2: 168,431,987 (GRCm39)	I42S	probably benign	Het
Nlgn3	G	A	X: 100,361,891 (GRCm39)	V287I	probably benign	Het
Npy6r	C	T	18: 44,409,686 (GRCm39)	T369I	probably benign	Het
Or7a36	A	G	10: 78,820,143 (GRCm39)	E173G	probably benign	Het
Ptprb	A	G	10: 116,179,820 (GRCm39)	T1413A	probably benign	Het
Ptprc	A	G	1: 138,017,304 (GRCm39)	S624P	probably benign	Het
Pum3	A	G	19: 27,377,169 (GRCm39)	V441A	probably damaging	Het
Ranbp2	T	A	10: 58,315,860 (GRCm39)	D2193E	probably damaging	Het
Rbl1	A	T	2: 157,017,397 (GRCm39)		probably benign	Het
Rnf167	T	C	11: 70,540,906 (GRCm39)		probably benign	Het
Sdr9c7	T	C	10: 127,738,259 (GRCm39)	V179A	probably damaging	Het
Sema3c	A	G	5: 17,932,615 (GRCm39)	N706S	possibly damaging	Het
Stt3a	T	C	9: 36,646,762 (GRCm39)	Y617C	probably damaging	Het
Tdrd6	T	A	17: 43,936,966 (GRCm39)	S1361C	probably damaging	Het
Tha1	A	C	11: 117,760,502 (GRCm39)	S241A	probably damaging	Het
Tti1	G	A	2: 157,850,432 (GRCm39)	A269V	probably benign	Het
Ugt2a1	A	G	5: 87,633,886 (GRCm39)		probably null	Het
Vmn2r10	T	C	5: 109,143,761 (GRCm39)	T730A	possibly damaging	Het

Other mutations in Gm38706

Allele	Source	Chr	Coord	Type	Predicted Effect
R4078:Gm38706	UTSW	6	130,460,700 (GRCm39)	exon	noncoding transcript
R4446:Gm38706	UTSW	6	130,460,273 (GRCm39)	exon	noncoding transcript
R5008:Gm38706	UTSW	6	130,461,983 (GRCm39)	exon	noncoding transcript
R5008:Gm38706	UTSW	6	130,461,580 (GRCm39)	exon	noncoding transcript
R5161:Gm38706	UTSW	6	130,459,868 (GRCm39)	unclassified	noncoding transcript
R5382:Gm38706	UTSW	6	130,460,744 (GRCm39)	exon	noncoding transcript
R5724:Gm38706	UTSW	6	130,459,963 (GRCm39)	unclassified	noncoding transcript
R5790:Gm38706	UTSW	6	130,461,961 (GRCm39)	exon	noncoding transcript

Predicted Primers

PCR Primer
(F):5'- AGTGAACTTGAAGTGTTGAGGA -3'
(R):5'- TTCAAGTTCATTACAGAATCCACAC -3'

Sequencing Primer
(F):5'- AGTGAACAGTAAGCTCTGCGTTC -3'
(R):5'- CTCAGATCTTAAAGTTCACCACAG -3'

Posted On

2016-06-21