Incidental Mutation 'R0453:Usp40'
| ID |
39733 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Usp40
|
| Ensembl Gene |
ENSMUSG00000005501 |
| Gene Name |
ubiquitin specific peptidase 40 |
| Synonyms |
B230215L03Rik |
| MMRRC Submission |
038653-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0453 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
1 |
| Chromosomal Location |
87872841-87936273 bp(-) (GRCm39) |
| Type of Mutation |
makesense |
| DNA Base Change (assembly) |
A to G
at 87874320 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Stop codon to Glutamine
at position 1236
(*1236Q)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000140107
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000027517]
[ENSMUST00000040783]
[ENSMUST00000187758]
[ENSMUST00000188332]
[ENSMUST00000189448]
[ENSMUST00000190061]
|
| AlphaFold |
Q8BWR4 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000027517
|
| SMART Domains |
Protein: ENSMUSP00000027517
Gene: ENSMUSG00000070738
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
36 |
N/A |
INTRINSIC |
|
PH
|
54 |
148 |
1.7e-16 |
SMART |
|
C1
|
164 |
213 |
2.48e-15 |
SMART |
|
low complexity region
|
221 |
232 |
N/A |
INTRINSIC |
|
C1
|
236 |
286 |
8.56e-10 |
SMART |
|
DAGKc
|
321 |
446 |
9.44e-62 |
SMART |
|
low complexity region
|
691 |
710 |
N/A |
INTRINSIC |
|
DAGKa
|
765 |
922 |
1.25e-98 |
SMART |
|
low complexity region
|
1128 |
1139 |
N/A |
INTRINSIC |
|
SAM
|
1148 |
1214 |
2.16e-22 |
SMART |
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000040783
AA Change: *1147Q
|
| SMART Domains |
Protein: ENSMUSP00000038533
Gene: ENSMUSG00000005501
AA Change: *1147Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:UCH
|
40 |
344 |
1.1e-31 |
PFAM |
|
Pfam:UCH_1
|
41 |
320 |
1.2e-20 |
PFAM |
|
low complexity region
|
641 |
650 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000186670
|
| Predicted Effect |
probably null
Transcript: ENSMUST00000187758
AA Change: *1236Q
|
| SMART Domains |
Protein: ENSMUSP00000140107
Gene: ENSMUSG00000005501
AA Change: *1236Q
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:UCH
|
40 |
346 |
8.7e-41 |
PFAM |
|
Pfam:UCH_1
|
41 |
319 |
2.4e-22 |
PFAM |
|
low complexity region
|
641 |
650 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000188332
|
| SMART Domains |
Protein: ENSMUSP00000140574
Gene: ENSMUSG00000005501
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:UCH
|
40 |
70 |
5.9e-6 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000189409
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000189448
|
| SMART Domains |
Protein: ENSMUSP00000139626
Gene: ENSMUSG00000070738
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
82 |
93 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000190061
|
| SMART Domains |
Protein: ENSMUSP00000139658
Gene: ENSMUSG00000070738
| Domain | Start | End | E-Value | Type |
|---|
|
DAGKa
|
1 |
95 |
7.6e-26 |
SMART |
|
Blast:DAGKa
|
119 |
188 |
1e-23 |
BLAST |
|
low complexity region
|
301 |
312 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.8596 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.4%
- 20x: 93.6%
|
| Validation Efficiency |
99% (97/98) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] Modification of cellular proteins by ubiquitin is an essential regulatory mechanism controlled by the coordinated action of multiple ubiquitin-conjugating and deubiquitinating enzymes. USP40 belongs to a large family of cysteine proteases that function as deubiquitinating enzymes (Quesada et al., 2004 [PubMed 14715245]).[supplied by OMIM, Mar 2008]
|
| Allele List at MGI |
All alleles(4) : Targeted, other(2) Gene trapped(2) |
| Other mutations in this stock |
Total: 97 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Acad10 |
T |
A |
5: 121,765,445 (GRCm39) |
K843* |
probably null |
Het |
| Adam26b |
T |
C |
8: 43,973,387 (GRCm39) |
I538M |
probably benign |
Het |
| Adamtsl1 |
T |
C |
4: 86,150,852 (GRCm39) |
Y337H |
probably damaging |
Het |
| Ak7 |
T |
C |
12: 105,682,307 (GRCm39) |
M156T |
probably damaging |
Het |
| Aldh3a1 |
A |
G |
11: 61,106,338 (GRCm39) |
M238V |
probably benign |
Het |
| Asic4 |
T |
A |
1: 75,450,155 (GRCm39) |
|
probably benign |
Het |
| AW551984 |
A |
G |
9: 39,511,937 (GRCm39) |
S25P |
probably damaging |
Het |
| Bbs7 |
T |
A |
3: 36,661,818 (GRCm39) |
Y127F |
possibly damaging |
Het |
| Bco1 |
G |
A |
8: 117,835,516 (GRCm39) |
E156K |
possibly damaging |
Het |
| Becn1 |
T |
C |
11: 101,181,275 (GRCm39) |
D342G |
probably damaging |
Het |
| Birc6 |
T |
A |
17: 74,956,749 (GRCm39) |
I3575N |
probably damaging |
Het |
| Brd10 |
T |
C |
19: 29,731,068 (GRCm39) |
Y715C |
probably damaging |
Het |
| Cc2d2a |
A |
T |
5: 43,860,636 (GRCm39) |
M522L |
probably benign |
Het |
| Cerkl |
A |
G |
2: 79,172,795 (GRCm39) |
F293L |
probably benign |
Het |
| Chil3 |
T |
G |
3: 106,056,221 (GRCm39) |
N311T |
probably benign |
Het |
| Cpeb2 |
T |
A |
5: 43,443,056 (GRCm39) |
|
probably benign |
Het |
| Cpxm2 |
A |
G |
7: 131,730,134 (GRCm39) |
S162P |
probably damaging |
Het |
| Cracr2b |
A |
C |
7: 141,044,176 (GRCm39) |
E136A |
probably damaging |
Het |
| Cyp2a4 |
T |
A |
7: 26,012,258 (GRCm39) |
M347K |
probably benign |
Het |
| Dicer1 |
C |
A |
12: 104,668,889 (GRCm39) |
R1264S |
probably benign |
Het |
| Dlgap1 |
T |
A |
17: 71,068,341 (GRCm39) |
N609K |
probably benign |
Het |
| Dnhd1 |
A |
G |
7: 105,323,651 (GRCm39) |
T641A |
probably benign |
Het |
| Egfl8 |
T |
C |
17: 34,833,856 (GRCm39) |
Y74C |
probably damaging |
Het |
| Esyt1 |
A |
G |
10: 128,348,078 (GRCm39) |
S901P |
probably benign |
Het |
| Fam83e |
A |
T |
7: 45,373,372 (GRCm39) |
D246V |
probably damaging |
Het |
| Galnt2 |
T |
C |
8: 125,065,323 (GRCm39) |
|
probably benign |
Het |
| Hdc |
A |
G |
2: 126,436,871 (GRCm39) |
|
probably benign |
Het |
| Herc1 |
A |
C |
9: 66,307,054 (GRCm39) |
Q958P |
probably benign |
Het |
| Iqcg |
T |
A |
16: 32,870,213 (GRCm39) |
|
probably benign |
Het |
| Iqub |
A |
T |
6: 24,450,829 (GRCm39) |
F590Y |
probably damaging |
Het |
| Jak2 |
T |
C |
19: 29,289,238 (GRCm39) |
I1130T |
probably benign |
Het |
| Kbtbd11 |
G |
A |
8: 15,077,499 (GRCm39) |
A33T |
probably benign |
Het |
| Kcnip4 |
A |
G |
5: 48,667,054 (GRCm39) |
L37P |
probably damaging |
Het |
| Klk6 |
A |
G |
7: 43,477,963 (GRCm39) |
N112D |
probably damaging |
Het |
| Kmt2c |
G |
A |
5: 25,559,745 (GRCm39) |
T1011I |
probably damaging |
Het |
| Knl1 |
A |
T |
2: 118,898,869 (GRCm39) |
K190M |
probably damaging |
Het |
| Lama3 |
T |
A |
18: 12,598,535 (GRCm39) |
S981T |
possibly damaging |
Het |
| Lrrc18 |
T |
C |
14: 32,730,608 (GRCm39) |
L49P |
probably damaging |
Het |
| Lrrc31 |
T |
C |
3: 30,741,674 (GRCm39) |
E245G |
probably damaging |
Het |
| Lypd10 |
T |
A |
7: 24,413,712 (GRCm39) |
S243T |
probably benign |
Het |
| Macf1 |
T |
C |
4: 123,338,737 (GRCm39) |
I2456M |
probably benign |
Het |
| Mcm6 |
T |
A |
1: 128,261,292 (GRCm39) |
T771S |
probably benign |
Het |
| Met |
A |
C |
6: 17,534,197 (GRCm39) |
Y680S |
possibly damaging |
Het |
| Mixl1 |
T |
A |
1: 180,524,211 (GRCm39) |
T123S |
probably damaging |
Het |
| Myh8 |
A |
T |
11: 67,183,731 (GRCm39) |
I787F |
probably benign |
Het |
| Myocd |
A |
G |
11: 65,087,051 (GRCm39) |
F292S |
probably damaging |
Het |
| Neb |
T |
C |
2: 52,203,902 (GRCm39) |
|
probably null |
Het |
| Nfe2l1 |
A |
G |
11: 96,718,194 (GRCm39) |
S114P |
probably damaging |
Het |
| Nrxn2 |
T |
C |
19: 6,541,551 (GRCm39) |
S986P |
probably damaging |
Het |
| Oprl1 |
T |
C |
2: 181,360,527 (GRCm39) |
|
probably null |
Het |
| Or11h6 |
T |
C |
14: 50,880,461 (GRCm39) |
V241A |
possibly damaging |
Het |
| Or4a73 |
A |
T |
2: 89,421,095 (GRCm39) |
Y121* |
probably null |
Het |
| Or5b101 |
T |
G |
19: 13,005,295 (GRCm39) |
T133P |
probably damaging |
Het |
| Or6c8 |
A |
G |
10: 128,915,640 (GRCm39) |
F64S |
probably damaging |
Het |
| Or8b53 |
G |
A |
9: 38,667,425 (GRCm39) |
G147D |
probably damaging |
Het |
| Or8c9 |
A |
T |
9: 38,241,467 (GRCm39) |
T195S |
probably benign |
Het |
| Panx2 |
T |
A |
15: 88,952,610 (GRCm39) |
I359N |
probably damaging |
Het |
| Pik3c2b |
T |
A |
1: 133,005,134 (GRCm39) |
V545E |
probably damaging |
Het |
| Piwil4 |
T |
C |
9: 14,638,748 (GRCm39) |
N259S |
probably benign |
Het |
| Plcxd2 |
A |
T |
16: 45,800,919 (GRCm39) |
F102I |
probably damaging |
Het |
| Pld5 |
A |
T |
1: 175,917,522 (GRCm39) |
M75K |
possibly damaging |
Het |
| Pmp22 |
T |
A |
11: 63,041,929 (GRCm39) |
|
probably benign |
Het |
| Polr2a |
A |
G |
11: 69,631,845 (GRCm39) |
S1074P |
possibly damaging |
Het |
| Pop1 |
T |
A |
15: 34,526,352 (GRCm39) |
V649E |
possibly damaging |
Het |
| Prc1 |
A |
G |
7: 79,962,850 (GRCm39) |
N548S |
probably damaging |
Het |
| Prss51 |
T |
C |
14: 64,334,588 (GRCm39) |
L202P |
probably damaging |
Het |
| Rhpn1 |
T |
C |
15: 75,585,428 (GRCm39) |
S576P |
possibly damaging |
Het |
| Rictor |
A |
G |
15: 6,738,123 (GRCm39) |
D20G |
probably benign |
Het |
| Rpl13a-ps1 |
A |
T |
19: 50,018,645 (GRCm39) |
L177* |
probably null |
Het |
| Rpl23a-ps1 |
T |
G |
1: 46,021,087 (GRCm39) |
|
noncoding transcript |
Het |
| Saa2 |
A |
G |
7: 46,402,902 (GRCm39) |
D51G |
probably damaging |
Het |
| Sec31a |
A |
T |
5: 100,551,977 (GRCm39) |
|
probably benign |
Het |
| Secisbp2 |
G |
A |
13: 51,837,361 (GRCm39) |
E841K |
possibly damaging |
Het |
| Serinc1 |
A |
G |
10: 57,393,306 (GRCm39) |
Y437H |
probably damaging |
Het |
| Slc39a12 |
A |
T |
2: 14,440,492 (GRCm39) |
H481L |
probably benign |
Het |
| Suz12 |
T |
A |
11: 79,920,859 (GRCm39) |
N586K |
probably damaging |
Het |
| Synm |
T |
C |
7: 67,386,630 (GRCm39) |
Y344C |
possibly damaging |
Het |
| Tas2r104 |
A |
G |
6: 131,662,304 (GRCm39) |
V135A |
probably benign |
Het |
| Tdrd9 |
T |
C |
12: 112,034,673 (GRCm39) |
S1371P |
probably benign |
Het |
| Tg |
T |
A |
15: 66,700,382 (GRCm39) |
D893E |
probably benign |
Het |
| Thoc5 |
C |
A |
11: 4,868,217 (GRCm39) |
D423E |
possibly damaging |
Het |
| Trim11 |
G |
A |
11: 58,881,361 (GRCm39) |
R418H |
probably damaging |
Het |
| Trim52 |
T |
G |
14: 106,344,399 (GRCm39) |
V19G |
probably damaging |
Het |
| Tuba4a |
C |
A |
1: 75,192,502 (GRCm39) |
V371L |
probably damaging |
Het |
| Ugt8a |
A |
G |
3: 125,708,606 (GRCm39) |
V168A |
probably benign |
Het |
| Ulk1 |
C |
T |
5: 110,938,951 (GRCm39) |
G496R |
probably damaging |
Het |
| Vmn2r100 |
C |
A |
17: 19,742,382 (GRCm39) |
P252Q |
possibly damaging |
Het |
| Vmn2r24 |
A |
G |
6: 123,757,350 (GRCm39) |
|
probably null |
Het |
| Vmn2r53 |
A |
G |
7: 12,316,338 (GRCm39) |
Y494H |
probably damaging |
Het |
| Vmn2r65 |
T |
A |
7: 84,595,442 (GRCm39) |
D414V |
probably benign |
Het |
| Wdr26 |
A |
T |
1: 181,010,444 (GRCm39) |
L519* |
probably null |
Het |
| Wnk1 |
A |
G |
6: 119,940,112 (GRCm39) |
V173A |
probably damaging |
Het |
| Zfp217 |
C |
T |
2: 169,957,382 (GRCm39) |
A539T |
probably benign |
Het |
| Zfp318 |
T |
C |
17: 46,707,634 (GRCm39) |
S231P |
probably damaging |
Het |
| Zfp398 |
T |
C |
6: 47,842,782 (GRCm39) |
V146A |
probably benign |
Het |
| Zfp410 |
T |
C |
12: 84,378,486 (GRCm39) |
M270T |
probably damaging |
Het |
| Zfp445 |
A |
T |
9: 122,682,578 (GRCm39) |
H454Q |
possibly damaging |
Het |
|
| Other mutations in Usp40 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00264:Usp40
|
APN |
1 |
87,931,960 (GRCm39) |
splice site |
probably benign |
|
|
IGL00828:Usp40
|
APN |
1 |
87,906,028 (GRCm39) |
unclassified |
probably benign |
|
|
IGL01090:Usp40
|
APN |
1 |
87,890,187 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01123:Usp40
|
APN |
1 |
87,913,845 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01401:Usp40
|
APN |
1 |
87,921,920 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02506:Usp40
|
APN |
1 |
87,909,738 (GRCm39) |
missense |
probably damaging |
0.98 |
|
IGL02580:Usp40
|
APN |
1 |
87,908,688 (GRCm39) |
splice site |
probably null |
|
|
IGL02625:Usp40
|
APN |
1 |
87,877,739 (GRCm39) |
missense |
probably benign |
0.19 |
|
IGL02811:Usp40
|
APN |
1 |
87,923,458 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02958:Usp40
|
APN |
1 |
87,906,207 (GRCm39) |
missense |
probably damaging |
0.99 |
|
Brink
|
UTSW |
1 |
87,908,755 (GRCm39) |
missense |
probably benign |
0.11 |
|
void
|
UTSW |
1 |
87,923,435 (GRCm39) |
nonsense |
probably null |
|
|
G5030:Usp40
|
UTSW |
1 |
87,921,941 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0019:Usp40
|
UTSW |
1 |
87,906,133 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0282:Usp40
|
UTSW |
1 |
87,908,680 (GRCm39) |
splice site |
probably benign |
|
|
R0646:Usp40
|
UTSW |
1 |
87,906,244 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1440:Usp40
|
UTSW |
1 |
87,909,808 (GRCm39) |
missense |
probably benign |
0.01 |
|
R1490:Usp40
|
UTSW |
1 |
87,916,687 (GRCm39) |
nonsense |
probably null |
|
|
R1620:Usp40
|
UTSW |
1 |
87,921,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1881:Usp40
|
UTSW |
1 |
87,921,993 (GRCm39) |
missense |
probably benign |
0.08 |
|
R1903:Usp40
|
UTSW |
1 |
87,909,778 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1912:Usp40
|
UTSW |
1 |
87,874,368 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1919:Usp40
|
UTSW |
1 |
87,923,564 (GRCm39) |
missense |
possibly damaging |
0.75 |
|
R1976:Usp40
|
UTSW |
1 |
87,906,258 (GRCm39) |
missense |
probably benign |
0.00 |
|
R2111:Usp40
|
UTSW |
1 |
87,877,936 (GRCm39) |
missense |
probably benign |
0.17 |
|
R2112:Usp40
|
UTSW |
1 |
87,877,936 (GRCm39) |
missense |
probably benign |
0.17 |
|
R2163:Usp40
|
UTSW |
1 |
87,923,580 (GRCm39) |
splice site |
probably benign |
|
|
R2432:Usp40
|
UTSW |
1 |
87,909,804 (GRCm39) |
missense |
probably benign |
|
|
R2865:Usp40
|
UTSW |
1 |
87,877,701 (GRCm39) |
nonsense |
probably null |
|
|
R3885:Usp40
|
UTSW |
1 |
87,894,991 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4360:Usp40
|
UTSW |
1 |
87,880,083 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4370:Usp40
|
UTSW |
1 |
87,925,597 (GRCm39) |
missense |
probably benign |
|
|
R4496:Usp40
|
UTSW |
1 |
87,923,459 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R4714:Usp40
|
UTSW |
1 |
87,894,901 (GRCm39) |
splice site |
probably null |
|
|
R4888:Usp40
|
UTSW |
1 |
87,913,923 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R4944:Usp40
|
UTSW |
1 |
87,880,077 (GRCm39) |
missense |
probably benign |
0.10 |
|
R5269:Usp40
|
UTSW |
1 |
87,923,504 (GRCm39) |
missense |
probably benign |
0.01 |
|
R5629:Usp40
|
UTSW |
1 |
87,908,731 (GRCm39) |
missense |
probably benign |
|
|
R5696:Usp40
|
UTSW |
1 |
87,923,474 (GRCm39) |
missense |
probably benign |
0.27 |
|
R5756:Usp40
|
UTSW |
1 |
87,879,413 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
R5887:Usp40
|
UTSW |
1 |
87,927,592 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5910:Usp40
|
UTSW |
1 |
87,896,122 (GRCm39) |
nonsense |
probably null |
|
|
R6014:Usp40
|
UTSW |
1 |
87,907,738 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6044:Usp40
|
UTSW |
1 |
87,917,872 (GRCm39) |
missense |
probably benign |
|
|
R6083:Usp40
|
UTSW |
1 |
87,906,281 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6299:Usp40
|
UTSW |
1 |
87,925,649 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6625:Usp40
|
UTSW |
1 |
87,894,935 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6757:Usp40
|
UTSW |
1 |
87,907,759 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6810:Usp40
|
UTSW |
1 |
87,908,755 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7110:Usp40
|
UTSW |
1 |
87,913,884 (GRCm39) |
missense |
probably benign |
0.11 |
|
R7573:Usp40
|
UTSW |
1 |
87,913,794 (GRCm39) |
missense |
probably benign |
0.09 |
|
R7575:Usp40
|
UTSW |
1 |
87,877,682 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7634:Usp40
|
UTSW |
1 |
87,890,152 (GRCm39) |
nonsense |
probably null |
|
|
R7756:Usp40
|
UTSW |
1 |
87,894,922 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7767:Usp40
|
UTSW |
1 |
87,909,900 (GRCm39) |
missense |
probably benign |
0.01 |
|
R7861:Usp40
|
UTSW |
1 |
87,909,852 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7881:Usp40
|
UTSW |
1 |
87,923,435 (GRCm39) |
nonsense |
probably null |
|
|
R7896:Usp40
|
UTSW |
1 |
87,906,201 (GRCm39) |
missense |
possibly damaging |
0.77 |
|
R8119:Usp40
|
UTSW |
1 |
87,895,400 (GRCm39) |
splice site |
probably null |
|
|
R8354:Usp40
|
UTSW |
1 |
87,908,694 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8358:Usp40
|
UTSW |
1 |
87,908,770 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8425:Usp40
|
UTSW |
1 |
87,887,558 (GRCm39) |
missense |
probably benign |
|
|
R8446:Usp40
|
UTSW |
1 |
87,906,190 (GRCm39) |
missense |
probably benign |
|
|
R8454:Usp40
|
UTSW |
1 |
87,908,694 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8744:Usp40
|
UTSW |
1 |
87,911,491 (GRCm39) |
missense |
probably benign |
|
|
R9002:Usp40
|
UTSW |
1 |
87,935,063 (GRCm39) |
missense |
probably benign |
|
|
R9033:Usp40
|
UTSW |
1 |
87,923,499 (GRCm39) |
utr 3 prime |
probably benign |
|
|
R9210:Usp40
|
UTSW |
1 |
87,885,035 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R9245:Usp40
|
UTSW |
1 |
87,878,009 (GRCm39) |
missense |
probably benign |
|
|
R9331:Usp40
|
UTSW |
1 |
87,901,828 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9378:Usp40
|
UTSW |
1 |
87,885,032 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9379:Usp40
|
UTSW |
1 |
87,881,889 (GRCm39) |
missense |
probably benign |
|
|
R9501:Usp40
|
UTSW |
1 |
87,925,557 (GRCm39) |
missense |
probably benign |
0.01 |
|
R9535:Usp40
|
UTSW |
1 |
87,935,161 (GRCm39) |
start gained |
probably benign |
|
|
R9537:Usp40
|
UTSW |
1 |
87,935,117 (GRCm39) |
missense |
probably benign |
0.01 |
|
RF006:Usp40
|
UTSW |
1 |
87,894,917 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
Z1177:Usp40
|
UTSW |
1 |
87,896,136 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AGAAGTGCCATCCCTTCGCCTATC -3'
(R):5'- TGGGAGCCATTCTAAGTACCCTCAAC -3'
Sequencing Primer
(F):5'- GCCTATCACAAAGCTGAAGACTTG -3'
(R):5'- tgccctctttctgacctcc -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation