Incidental Mutation 'R5256:Atrn'
| ID |
399587 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Atrn
|
| Ensembl Gene |
ENSMUSG00000027312 |
| Gene Name |
attractin |
| Synonyms |
Mgca |
| MMRRC Submission |
042827-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R5256 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
2 |
| Chromosomal Location |
130748415-130872253 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 130787939 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 247
(D247G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000028781
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000028781]
|
| AlphaFold |
Q9WU60 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000028781
AA Change: D247G
PolyPhen 2
Score 0.394 (Sensitivity: 0.90; Specificity: 0.89)
|
| SMART Domains |
Protein: ENSMUSP00000028781
Gene: ENSMUSG00000027312
AA Change: D247G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
9 |
N/A |
INTRINSIC |
|
low complexity region
|
51 |
97 |
N/A |
INTRINSIC |
|
EGF
|
99 |
129 |
9.85e-5 |
SMART |
|
CUB
|
131 |
247 |
7.85e-18 |
SMART |
|
EGF
|
248 |
282 |
1.47e1 |
SMART |
|
Pfam:Kelch_1
|
339 |
382 |
1.1e-7 |
PFAM |
|
Pfam:Kelch_5
|
389 |
434 |
2.5e-7 |
PFAM |
|
Pfam:Kelch_6
|
390 |
439 |
3.3e-8 |
PFAM |
|
Pfam:Kelch_1
|
553 |
606 |
8.4e-8 |
PFAM |
|
PSI
|
646 |
693 |
7.41e-7 |
SMART |
|
PSI
|
702 |
747 |
8.64e-8 |
SMART |
|
PSI
|
754 |
799 |
2.11e-2 |
SMART |
|
CLECT
|
787 |
918 |
6.14e-20 |
SMART |
|
PSI
|
931 |
982 |
1.11e-5 |
SMART |
|
PSI
|
985 |
1060 |
1.2e-6 |
SMART |
|
EGF_Lam
|
1062 |
1105 |
1.97e-4 |
SMART |
|
EGF_like
|
1108 |
1154 |
3.9e0 |
SMART |
|
transmembrane domain
|
1278 |
1300 |
N/A |
INTRINSIC |
|
low complexity region
|
1310 |
1322 |
N/A |
INTRINSIC |
|
low complexity region
|
1373 |
1385 |
N/A |
INTRINSIC |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000134964
|
| Meta Mutation Damage Score |
0.0997 |
| Coding Region Coverage |
- 1x: 99.1%
- 3x: 98.3%
- 10x: 96.4%
- 20x: 92.8%
|
| Validation Efficiency |
97% (95/98) |
| MGI Phenotype |
FUNCTION: This gene encodes a widely expressed transmembrane glycoprotein that plays important roles in diverse physiological processes such as regulation of hair pigmentation, monocyte-T cell interaction and control of energy homeostasis. The encoded preproprotein undergoes proteolytic processing to generate a mature, functional protein. Certain mutations in this gene are responsible for the mahogany mouse phenotype of dark brown or black coat on a normally agouti background. Mice with loss-of-function mutations in this gene exhibit black coat color, tremor, adiposity, higher basal metabolic rate, juvenile-onset hypomyelination and age-dependent spongiform neurodegeneration of the central nervous system. [provided by RefSeq, Jul 2016]
PHENOTYPE: Some mutant homozygotes exhibit decreases in phaeomelanin synthesis, body weight, and adiposity; increases in locomotion, and abnormal myelination and vacuolation of the central nervous system resulting in tremors. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 92 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| A730015C16Rik |
C |
A |
4: 108,705,262 (GRCm39) |
|
probably benign |
Het |
| Actr1b |
T |
C |
1: 36,739,173 (GRCm39) |
H372R |
probably benign |
Het |
| Ampd2 |
C |
A |
3: 107,986,865 (GRCm39) |
|
probably benign |
Het |
| Anapc4 |
A |
G |
5: 53,020,936 (GRCm39) |
S612G |
probably benign |
Het |
| Arhgef7 |
T |
C |
8: 11,850,811 (GRCm39) |
L141P |
probably damaging |
Het |
| Atl1 |
A |
G |
12: 70,006,107 (GRCm39) |
D471G |
probably damaging |
Het |
| Bag1 |
T |
A |
4: 40,948,022 (GRCm39) |
R61W |
probably damaging |
Het |
| Card10 |
C |
T |
15: 78,662,451 (GRCm39) |
R898H |
probably damaging |
Het |
| Cct6b |
G |
A |
11: 82,655,046 (GRCm39) |
A3V |
probably damaging |
Het |
| Cfap54 |
A |
T |
10: 92,770,953 (GRCm39) |
L2097* |
probably null |
Het |
| Cfap54 |
T |
C |
10: 92,880,885 (GRCm39) |
|
probably null |
Het |
| Chd5 |
T |
C |
4: 152,456,554 (GRCm39) |
F964L |
probably benign |
Het |
| Cog5 |
A |
G |
12: 31,936,204 (GRCm39) |
T584A |
probably benign |
Het |
| Cpa2 |
T |
A |
6: 30,547,196 (GRCm39) |
N157K |
probably damaging |
Het |
| Cpeb1 |
A |
T |
7: 81,001,587 (GRCm39) |
M440K |
probably damaging |
Het |
| Cracr2a |
G |
A |
6: 127,580,992 (GRCm39) |
C56Y |
probably damaging |
Het |
| Ddb2 |
A |
C |
2: 91,067,073 (GRCm39) |
L30R |
probably damaging |
Het |
| Dlk1 |
T |
A |
12: 109,425,697 (GRCm39) |
I190N |
probably damaging |
Het |
| Dnaaf4 |
T |
C |
9: 72,879,362 (GRCm39) |
|
probably null |
Het |
| Dnajc13 |
T |
A |
9: 104,080,528 (GRCm39) |
Y851F |
possibly damaging |
Het |
| Dop1a |
T |
A |
9: 86,397,381 (GRCm39) |
L895Q |
probably damaging |
Het |
| F7 |
G |
A |
8: 13,080,763 (GRCm39) |
C122Y |
probably damaging |
Het |
| Frrs1 |
T |
C |
3: 116,696,749 (GRCm39) |
V573A |
possibly damaging |
Het |
| Galnt2l |
T |
C |
8: 122,997,175 (GRCm39) |
|
probably benign |
Het |
| Gm17541 |
A |
T |
12: 4,739,672 (GRCm39) |
|
probably benign |
Het |
| Gm5519 |
A |
T |
19: 33,800,576 (GRCm39) |
H90L |
probably damaging |
Het |
| Gm5526 |
T |
A |
1: 45,896,569 (GRCm39) |
|
noncoding transcript |
Het |
| Gm5709 |
A |
T |
3: 59,509,971 (GRCm39) |
|
noncoding transcript |
Het |
| Golga4 |
T |
A |
9: 118,385,569 (GRCm39) |
V869D |
possibly damaging |
Het |
| Grm7 |
A |
T |
6: 111,335,182 (GRCm39) |
Q531L |
probably benign |
Het |
| Hnrnpu |
C |
A |
1: 178,163,458 (GRCm39) |
C265F |
unknown |
Het |
| Hoxd3 |
G |
A |
2: 74,577,211 (GRCm39) |
V364I |
possibly damaging |
Het |
| Hspb8 |
T |
C |
5: 116,547,532 (GRCm39) |
D150G |
probably damaging |
Het |
| Hydin |
C |
A |
8: 111,313,855 (GRCm39) |
N4244K |
possibly damaging |
Het |
| Ik |
A |
G |
18: 36,881,926 (GRCm39) |
D136G |
probably benign |
Het |
| Il11ra1 |
T |
C |
4: 41,767,932 (GRCm39) |
|
probably benign |
Het |
| Jph1 |
T |
C |
1: 17,161,622 (GRCm39) |
I347V |
probably benign |
Het |
| Klk1 |
T |
A |
7: 43,870,985 (GRCm39) |
|
probably benign |
Het |
| Lmcd1 |
T |
A |
6: 112,265,087 (GRCm39) |
|
probably benign |
Het |
| Lnx1 |
C |
T |
5: 74,846,315 (GRCm39) |
C45Y |
probably damaging |
Het |
| Macc1 |
T |
A |
12: 119,410,264 (GRCm39) |
M344K |
possibly damaging |
Het |
| Madcam1 |
A |
G |
10: 79,500,779 (GRCm39) |
E32G |
possibly damaging |
Het |
| Mat2a |
T |
C |
6: 72,411,316 (GRCm39) |
D383G |
probably benign |
Het |
| Mpst |
T |
A |
15: 78,297,849 (GRCm39) |
I289N |
probably damaging |
Het |
| Myh6 |
C |
T |
14: 55,190,118 (GRCm39) |
R1055Q |
probably damaging |
Het |
| Myh7 |
T |
C |
14: 55,216,965 (GRCm39) |
K1131E |
probably damaging |
Het |
| Ndrg3 |
A |
T |
2: 156,773,125 (GRCm39) |
|
probably benign |
Het |
| Nebl |
A |
G |
2: 17,438,786 (GRCm39) |
S209P |
probably benign |
Het |
| Nid2 |
A |
G |
14: 19,818,276 (GRCm39) |
|
probably null |
Het |
| Nup188 |
A |
T |
2: 30,220,761 (GRCm39) |
S945C |
probably damaging |
Het |
| Or1j21 |
A |
G |
2: 36,683,685 (GRCm39) |
M146V |
probably benign |
Het |
| Or5g23 |
C |
T |
2: 85,438,817 (GRCm39) |
V146I |
probably benign |
Het |
| Or8c11 |
A |
G |
9: 38,289,213 (GRCm39) |
N12S |
probably benign |
Het |
| Otx1 |
C |
A |
11: 21,947,037 (GRCm39) |
A91S |
probably damaging |
Het |
| Patl2 |
A |
G |
2: 121,959,368 (GRCm39) |
L32P |
probably damaging |
Het |
| Pcdh20 |
T |
A |
14: 88,705,813 (GRCm39) |
M496L |
probably benign |
Het |
| Pdzd2 |
A |
G |
15: 12,373,028 (GRCm39) |
V2369A |
possibly damaging |
Het |
| Pfn2 |
A |
G |
3: 57,754,812 (GRCm39) |
V31A |
probably damaging |
Het |
| Plxna4 |
T |
C |
6: 32,228,007 (GRCm39) |
N533S |
probably benign |
Het |
| Plxnb1 |
T |
C |
9: 108,943,661 (GRCm39) |
F1916S |
probably damaging |
Het |
| Ppp4r3b |
T |
C |
11: 29,138,293 (GRCm39) |
F214L |
probably benign |
Het |
| Prox1 |
T |
C |
1: 189,893,638 (GRCm39) |
D269G |
probably benign |
Het |
| Rapgef4 |
T |
C |
2: 71,864,378 (GRCm39) |
F71S |
probably damaging |
Het |
| Rft1 |
A |
G |
14: 30,383,243 (GRCm39) |
I94M |
probably benign |
Het |
| S100z |
T |
C |
13: 95,615,127 (GRCm39) |
I13V |
probably damaging |
Het |
| Serhl |
T |
A |
15: 82,986,835 (GRCm39) |
V117E |
probably damaging |
Het |
| Shroom1 |
G |
A |
11: 53,356,334 (GRCm39) |
R336Q |
probably benign |
Het |
| Sik3 |
A |
T |
9: 46,123,552 (GRCm39) |
Q1067L |
probably damaging |
Het |
| Slc22a30 |
G |
A |
19: 8,321,757 (GRCm39) |
Q436* |
probably null |
Het |
| Slc28a1 |
G |
A |
7: 80,771,869 (GRCm39) |
V118M |
probably damaging |
Het |
| Slco1a6 |
T |
A |
6: 142,078,427 (GRCm39) |
I153F |
probably benign |
Het |
| Ss18l1 |
T |
C |
2: 179,703,735 (GRCm39) |
Y323H |
unknown |
Het |
| Susd4 |
G |
T |
1: 182,719,824 (GRCm39) |
A480S |
possibly damaging |
Het |
| Syne3 |
A |
T |
12: 104,942,139 (GRCm39) |
M1K |
probably null |
Het |
| Synpo2l |
A |
T |
14: 20,711,082 (GRCm39) |
S513T |
probably benign |
Het |
| Tat |
A |
T |
8: 110,724,966 (GRCm39) |
N388I |
probably benign |
Het |
| Tbc1d1 |
A |
G |
5: 64,439,352 (GRCm39) |
Y619C |
probably damaging |
Het |
| Tbk1 |
G |
A |
10: 121,406,590 (GRCm39) |
T216M |
probably damaging |
Het |
| Tns1 |
C |
T |
1: 74,034,585 (GRCm39) |
|
probably benign |
Het |
| Trbv5 |
T |
C |
6: 41,039,318 (GRCm39) |
V9A |
possibly damaging |
Het |
| Trpm5 |
A |
G |
7: 142,636,040 (GRCm39) |
Y575H |
probably damaging |
Het |
| Ttn |
A |
T |
2: 76,570,045 (GRCm39) |
Y25203* |
probably null |
Het |
| Tubb3 |
C |
A |
8: 124,148,391 (GRCm39) |
D441E |
probably benign |
Het |
| Usp33 |
T |
A |
3: 152,097,333 (GRCm39) |
C850* |
probably null |
Het |
| Vdac1 |
G |
A |
11: 52,274,905 (GRCm39) |
|
probably null |
Het |
| Vmn1r232 |
T |
C |
17: 21,133,846 (GRCm39) |
I251M |
probably damaging |
Het |
| Vmn2r11 |
T |
G |
5: 109,202,658 (GRCm39) |
I140L |
probably benign |
Het |
| Vmn2r6 |
A |
T |
3: 64,464,263 (GRCm39) |
N190K |
probably benign |
Het |
| Vps51 |
T |
A |
19: 6,120,518 (GRCm39) |
H465L |
probably benign |
Het |
| Zfp318 |
T |
G |
17: 46,722,995 (GRCm39) |
I1666S |
probably benign |
Het |
| Zfp446 |
C |
T |
7: 12,713,231 (GRCm39) |
R90* |
probably null |
Het |
| Zgrf1 |
T |
A |
3: 127,396,094 (GRCm39) |
F547I |
probably damaging |
Het |
|
| Other mutations in Atrn |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00337:Atrn
|
APN |
2 |
130,799,999 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00571:Atrn
|
APN |
2 |
130,836,968 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01092:Atrn
|
APN |
2 |
130,789,556 (GRCm39) |
nonsense |
probably null |
|
|
IGL01572:Atrn
|
APN |
2 |
130,844,715 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01924:Atrn
|
APN |
2 |
130,777,485 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02116:Atrn
|
APN |
2 |
130,800,009 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02372:Atrn
|
APN |
2 |
130,844,674 (GRCm39) |
splice site |
probably benign |
|
|
IGL02390:Atrn
|
APN |
2 |
130,862,897 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
IGL02548:Atrn
|
APN |
2 |
130,814,202 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02749:Atrn
|
APN |
2 |
130,789,654 (GRCm39) |
splice site |
probably benign |
|
|
IGL02749:Atrn
|
APN |
2 |
130,812,064 (GRCm39) |
nonsense |
probably null |
|
|
BB010:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
BB020:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0026:Atrn
|
UTSW |
2 |
130,799,840 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0403:Atrn
|
UTSW |
2 |
130,748,779 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0479:Atrn
|
UTSW |
2 |
130,841,085 (GRCm39) |
nonsense |
probably null |
|
|
R0544:Atrn
|
UTSW |
2 |
130,828,746 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0570:Atrn
|
UTSW |
2 |
130,822,054 (GRCm39) |
missense |
probably benign |
0.01 |
|
R0606:Atrn
|
UTSW |
2 |
130,748,776 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R0617:Atrn
|
UTSW |
2 |
130,837,005 (GRCm39) |
critical splice donor site |
probably null |
|
|
R0658:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R1108:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1112:Atrn
|
UTSW |
2 |
130,841,081 (GRCm39) |
missense |
probably benign |
0.04 |
|
R1219:Atrn
|
UTSW |
2 |
130,862,927 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R1422:Atrn
|
UTSW |
2 |
130,799,834 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1524:Atrn
|
UTSW |
2 |
130,799,000 (GRCm39) |
missense |
probably benign |
0.15 |
|
R1653:Atrn
|
UTSW |
2 |
130,777,544 (GRCm39) |
missense |
probably benign |
|
|
R1795:Atrn
|
UTSW |
2 |
130,814,208 (GRCm39) |
missense |
probably benign |
|
|
R1807:Atrn
|
UTSW |
2 |
130,824,692 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R1920:Atrn
|
UTSW |
2 |
130,836,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1921:Atrn
|
UTSW |
2 |
130,836,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1935:Atrn
|
UTSW |
2 |
130,799,955 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1982:Atrn
|
UTSW |
2 |
130,812,142 (GRCm39) |
missense |
probably benign |
|
|
R2000:Atrn
|
UTSW |
2 |
130,777,508 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2143:Atrn
|
UTSW |
2 |
130,799,916 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2336:Atrn
|
UTSW |
2 |
130,799,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2679:Atrn
|
UTSW |
2 |
130,803,595 (GRCm39) |
critical splice donor site |
probably null |
|
|
R3426:Atrn
|
UTSW |
2 |
130,862,876 (GRCm39) |
missense |
probably benign |
0.06 |
|
R3909:Atrn
|
UTSW |
2 |
130,836,127 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4077:Atrn
|
UTSW |
2 |
130,806,850 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4162:Atrn
|
UTSW |
2 |
130,836,148 (GRCm39) |
splice site |
probably benign |
|
|
R4195:Atrn
|
UTSW |
2 |
130,775,332 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4364:Atrn
|
UTSW |
2 |
130,812,128 (GRCm39) |
missense |
probably benign |
0.39 |
|
R4465:Atrn
|
UTSW |
2 |
130,802,388 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4510:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4511:Atrn
|
UTSW |
2 |
130,777,497 (GRCm39) |
nonsense |
probably null |
|
|
R4527:Atrn
|
UTSW |
2 |
130,815,424 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4586:Atrn
|
UTSW |
2 |
130,823,962 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4592:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R4658:Atrn
|
UTSW |
2 |
130,775,349 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4735:Atrn
|
UTSW |
2 |
130,862,910 (GRCm39) |
missense |
probably benign |
0.06 |
|
R4960:Atrn
|
UTSW |
2 |
130,836,967 (GRCm39) |
nonsense |
probably null |
|
|
R4999:Atrn
|
UTSW |
2 |
130,817,874 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5066:Atrn
|
UTSW |
2 |
130,836,113 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R5080:Atrn
|
UTSW |
2 |
130,812,044 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5141:Atrn
|
UTSW |
2 |
130,841,050 (GRCm39) |
intron |
probably benign |
|
|
R5494:Atrn
|
UTSW |
2 |
130,864,995 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5678:Atrn
|
UTSW |
2 |
130,811,936 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R5752:Atrn
|
UTSW |
2 |
130,748,464 (GRCm39) |
unclassified |
probably benign |
|
|
R5931:Atrn
|
UTSW |
2 |
130,775,356 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R6023:Atrn
|
UTSW |
2 |
130,862,900 (GRCm39) |
missense |
probably benign |
0.25 |
|
R6176:Atrn
|
UTSW |
2 |
130,788,011 (GRCm39) |
missense |
probably benign |
0.31 |
|
R6377:Atrn
|
UTSW |
2 |
130,821,889 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6433:Atrn
|
UTSW |
2 |
130,864,947 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7226:Atrn
|
UTSW |
2 |
130,828,664 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7402:Atrn
|
UTSW |
2 |
130,789,520 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7541:Atrn
|
UTSW |
2 |
130,803,491 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7587:Atrn
|
UTSW |
2 |
130,822,034 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7872:Atrn
|
UTSW |
2 |
130,812,147 (GRCm39) |
critical splice donor site |
probably null |
|
|
R7910:Atrn
|
UTSW |
2 |
130,806,807 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7913:Atrn
|
UTSW |
2 |
130,812,131 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7933:Atrn
|
UTSW |
2 |
130,836,986 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8044:Atrn
|
UTSW |
2 |
130,777,449 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8079:Atrn
|
UTSW |
2 |
130,855,561 (GRCm39) |
missense |
probably null |
1.00 |
|
R8093:Atrn
|
UTSW |
2 |
130,817,908 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8203:Atrn
|
UTSW |
2 |
130,802,469 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8234:Atrn
|
UTSW |
2 |
130,864,920 (GRCm39) |
critical splice acceptor site |
probably null |
|
|
R8462:Atrn
|
UTSW |
2 |
130,777,504 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,846,494 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8816:Atrn
|
UTSW |
2 |
130,748,798 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8831:Atrn
|
UTSW |
2 |
130,748,521 (GRCm39) |
missense |
probably benign |
0.22 |
|
R8937:Atrn
|
UTSW |
2 |
130,841,157 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9161:Atrn
|
UTSW |
2 |
130,777,470 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9722:Atrn
|
UTSW |
2 |
130,803,536 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9786:Atrn
|
UTSW |
2 |
130,786,809 (GRCm39) |
missense |
probably damaging |
1.00 |
|
RF009:Atrn
|
UTSW |
2 |
130,748,842 (GRCm39) |
missense |
probably benign |
0.12 |
|
X0024:Atrn
|
UTSW |
2 |
130,800,059 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1088:Atrn
|
UTSW |
2 |
130,815,319 (GRCm39) |
missense |
probably benign |
|
|
Z1176:Atrn
|
UTSW |
2 |
130,788,113 (GRCm39) |
missense |
probably benign |
0.27 |
|
Z1177:Atrn
|
UTSW |
2 |
130,787,962 (GRCm39) |
missense |
probably damaging |
0.99 |
|
| Predicted Primers |
PCR Primer
(F):5'- TTCATTACTTGAGCCTGGGG -3'
(R):5'- TTTGAAGGGCAGCTCCTACC -3'
Sequencing Primer
(F):5'- GCTCTAGCTACACAGAGCTCTG -3'
(R):5'- CTACCCTGCCAGTGAGGAAAG -3'
|
| Posted On |
2016-07-06 |
Incidental Mutation