Incidental Mutation 'R5304:Kirrel1'
| ID |
404407 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Kirrel1
|
| Ensembl Gene |
ENSMUSG00000041734 |
| Gene Name |
kirre like nephrin family adhesion molecule 1 |
| Synonyms |
6720469N11Rik, Neph1, Kirrel1, Kirrel |
| MMRRC Submission |
042887-MU
|
| Accession Numbers |
|
| Essential gene? |
Essential
(E-score: 1.000)
|
| Stock # |
R5304 (G1)
|
| Quality Score |
225 |
|
Status
|
Validated
|
| Chromosome |
3 |
| Chromosomal Location |
86985900-87082054 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
T to A
at 86996902 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Histidine to Leucine
at position 300
(H300L)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000125525
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041732]
[ENSMUST00000107618]
[ENSMUST00000159976]
|
| AlphaFold |
Q80W68 |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000041732
AA Change: H300L
PolyPhen 2
Score 0.018 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000043756
Gene: ENSMUSG00000041734
AA Change: H300L
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000107618
AA Change: H300L
PolyPhen 2
Score 0.018 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000103243
Gene: ENSMUSG00000041734
AA Change: H300L
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000159976
AA Change: H300L
PolyPhen 2
Score 0.018 (Sensitivity: 0.95; Specificity: 0.80)
|
| SMART Domains |
Protein: ENSMUSP00000125525
Gene: ENSMUSG00000041734
AA Change: H300L
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
59 |
149 |
3.62e-10 |
SMART |
|
IG_like
|
160 |
252 |
1.27e1 |
SMART |
|
IG_like
|
261 |
337 |
1.89e1 |
SMART |
|
IGc2
|
352 |
410 |
3.28e-8 |
SMART |
|
IG_like
|
430 |
522 |
5.71e0 |
SMART |
|
transmembrane domain
|
529 |
551 |
N/A |
INTRINSIC |
|
low complexity region
|
694 |
712 |
N/A |
INTRINSIC |
|
| Meta Mutation Damage Score |
0.0998 |
| Coding Region Coverage |
- 1x: 99.4%
- 3x: 98.8%
- 10x: 97.5%
- 20x: 95.9%
|
| Validation Efficiency |
99% (87/88) |
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] NEPH1 is a member of the nephrin-like protein family, which includes NEPH2 (MIM 607761) and NEPH3 (MIM 607762). The cytoplasmic domains of these proteins interact with the C terminus of podocin (NPHS2; MIM 604766), and the genes are expressed in kidney podocytes, cells involved in ensuring size- and charge-selective ultrafiltration (Sellin et al., 2003 [PubMed 12424224]).[supplied by OMIM, Mar 2008]
PHENOTYPE: Mice homozygous for a gene trap insertion exhibit postnatal lethality and are small and sickly. Glomerular and tubular defects in the kidney result in severe proteinuria. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(121) : Targeted, other(2) Gene trapped(119) |
| Other mutations in this stock |
Total: 80 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adcy1 |
C |
T |
11: 7,014,198 (GRCm39) |
A200V |
probably benign |
Het |
| Adgrv1 |
T |
C |
13: 81,726,372 (GRCm39) |
D551G |
possibly damaging |
Het |
| Aldh3a2 |
A |
G |
11: 61,144,538 (GRCm39) |
V340A |
probably damaging |
Het |
| Amy1 |
C |
A |
3: 113,352,013 (GRCm39) |
C393F |
probably damaging |
Het |
| Ankrd16 |
T |
C |
2: 11,794,545 (GRCm39) |
V310A |
probably benign |
Het |
| Arhgef15 |
T |
C |
11: 68,838,063 (GRCm39) |
S686G |
probably null |
Het |
| Arid4b |
T |
A |
13: 14,361,514 (GRCm39) |
N659K |
probably benign |
Het |
| Asz1 |
C |
T |
6: 18,076,619 (GRCm39) |
R191Q |
probably benign |
Het |
| Atp2a3 |
A |
G |
11: 72,879,383 (GRCm39) |
I947V |
probably damaging |
Het |
| AW011738 |
G |
A |
4: 156,287,969 (GRCm39) |
|
probably benign |
Het |
| Bfsp1 |
G |
T |
2: 143,669,211 (GRCm39) |
T456K |
probably benign |
Het |
| Cdc25c |
T |
C |
18: 34,883,864 (GRCm39) |
T40A |
possibly damaging |
Het |
| Cdh20 |
G |
A |
1: 110,036,569 (GRCm39) |
C583Y |
probably damaging |
Het |
| Ceacam23 |
A |
C |
7: 17,636,617 (GRCm39) |
E231D |
probably benign |
Het |
| Cfap54 |
A |
T |
10: 92,656,968 (GRCm39) |
L3028Q |
probably damaging |
Het |
| Chd1 |
A |
G |
17: 15,975,213 (GRCm39) |
S1088G |
probably benign |
Het |
| Chd1 |
A |
T |
17: 15,990,530 (GRCm39) |
H1694L |
possibly damaging |
Het |
| Cstf3 |
G |
T |
2: 104,493,735 (GRCm39) |
E580* |
probably null |
Het |
| Dip2a |
A |
T |
10: 76,130,357 (GRCm39) |
M622K |
possibly damaging |
Het |
| Dlgap1 |
A |
T |
17: 71,122,202 (GRCm39) |
H877L |
probably damaging |
Het |
| Egfr |
G |
T |
11: 16,834,260 (GRCm39) |
M122I |
probably benign |
Het |
| Etfbkmt |
T |
A |
6: 149,048,704 (GRCm39) |
D114E |
probably damaging |
Het |
| Eva1c |
T |
C |
16: 90,666,551 (GRCm39) |
L158P |
probably damaging |
Het |
| Exo1 |
G |
A |
1: 175,720,542 (GRCm39) |
V287M |
probably damaging |
Het |
| Fam171a1 |
T |
C |
2: 3,226,654 (GRCm39) |
Y471H |
probably damaging |
Het |
| Fermt1 |
T |
A |
2: 132,783,986 (GRCm39) |
T8S |
probably benign |
Het |
| Fgfr2 |
G |
T |
7: 129,769,504 (GRCm39) |
P630T |
probably damaging |
Het |
| Fmo5 |
G |
A |
3: 97,558,938 (GRCm39) |
G466E |
probably damaging |
Het |
| Hcn4 |
A |
G |
9: 58,751,215 (GRCm39) |
I280M |
probably benign |
Het |
| Ifi208 |
A |
C |
1: 173,511,174 (GRCm39) |
K443T |
probably benign |
Het |
| Irs3 |
A |
G |
5: 137,643,003 (GRCm39) |
F145S |
probably benign |
Het |
| Krit1 |
A |
G |
5: 3,869,326 (GRCm39) |
Q340R |
probably damaging |
Het |
| Lipo5 |
T |
C |
19: 33,445,149 (GRCm39) |
D140G |
unknown |
Het |
| Lrrtm4 |
A |
T |
6: 79,999,683 (GRCm39) |
Q365L |
probably benign |
Het |
| Lrwd1 |
G |
T |
5: 136,160,004 (GRCm39) |
T353K |
possibly damaging |
Het |
| Lsm14a |
A |
T |
7: 34,053,154 (GRCm39) |
S240R |
possibly damaging |
Het |
| Map3k5 |
A |
G |
10: 19,983,984 (GRCm39) |
I870V |
probably benign |
Het |
| Matcap2 |
A |
T |
9: 22,335,528 (GRCm39) |
T49S |
probably benign |
Het |
| Mmp17 |
A |
T |
5: 129,671,678 (GRCm39) |
E76V |
probably null |
Het |
| Mphosph10 |
A |
G |
7: 64,038,732 (GRCm39) |
F272L |
probably damaging |
Het |
| Mtcl2 |
G |
A |
2: 156,865,737 (GRCm39) |
Q1127* |
probably null |
Het |
| Myh10 |
A |
G |
11: 68,655,071 (GRCm39) |
K380R |
probably damaging |
Het |
| Myo3b |
C |
T |
2: 70,257,232 (GRCm39) |
P1282L |
probably damaging |
Het |
| Nemp2 |
T |
C |
1: 52,682,238 (GRCm39) |
|
probably benign |
Het |
| Ola1 |
T |
C |
2: 73,029,778 (GRCm39) |
I114V |
probably damaging |
Het |
| Or4c3d |
T |
A |
2: 89,882,257 (GRCm39) |
H137L |
probably benign |
Het |
| Or8k28 |
T |
A |
2: 86,285,779 (GRCm39) |
T279S |
probably damaging |
Het |
| Pabpc4 |
T |
G |
4: 123,184,100 (GRCm39) |
D204E |
probably benign |
Het |
| Pigr |
A |
T |
1: 130,777,230 (GRCm39) |
M679L |
probably benign |
Het |
| Pik3c2b |
A |
T |
1: 132,998,146 (GRCm39) |
M341L |
possibly damaging |
Het |
| Plin4 |
T |
A |
17: 56,413,132 (GRCm39) |
T498S |
probably benign |
Het |
| Ppp2r5e |
A |
G |
12: 75,562,459 (GRCm39) |
S15P |
possibly damaging |
Het |
| Prdm13 |
T |
C |
4: 21,678,984 (GRCm39) |
Y502C |
probably damaging |
Het |
| Ptprk |
T |
C |
10: 28,468,050 (GRCm39) |
|
probably null |
Het |
| Rapgef6 |
T |
C |
11: 54,548,200 (GRCm39) |
S505P |
probably benign |
Het |
| Rgmb |
G |
T |
17: 16,040,990 (GRCm39) |
S199* |
probably null |
Het |
| Rgsl1 |
T |
C |
1: 153,703,238 (GRCm39) |
T173A |
probably damaging |
Het |
| Rhobtb1 |
G |
T |
10: 69,105,742 (GRCm39) |
K102N |
probably damaging |
Het |
| Ripor2 |
A |
T |
13: 24,858,649 (GRCm39) |
D147V |
probably damaging |
Het |
| Rsad2 |
A |
T |
12: 26,500,681 (GRCm39) |
V202E |
probably damaging |
Het |
| Slc1a6 |
A |
G |
10: 78,629,141 (GRCm39) |
N186S |
probably damaging |
Het |
| Sorbs3 |
G |
A |
14: 70,422,345 (GRCm39) |
R622* |
probably null |
Het |
| Spag9 |
C |
A |
11: 93,959,838 (GRCm39) |
D342E |
probably damaging |
Het |
| Srgap3 |
T |
C |
6: 112,743,900 (GRCm39) |
Y446C |
probably damaging |
Het |
| Thsd7b |
C |
T |
1: 129,605,980 (GRCm39) |
R574* |
probably null |
Het |
| Tmem74 |
A |
T |
15: 43,730,217 (GRCm39) |
Y275* |
probably null |
Het |
| Topors |
A |
T |
4: 40,262,541 (GRCm39) |
S248T |
possibly damaging |
Het |
| Trpm1 |
A |
T |
7: 63,858,694 (GRCm39) |
Y239F |
probably benign |
Het |
| Ttn |
T |
A |
2: 76,548,527 (GRCm39) |
Y30179F |
possibly damaging |
Het |
| Ugt2b34 |
A |
T |
5: 87,040,724 (GRCm39) |
F399L |
probably damaging |
Het |
| Ush2a |
A |
T |
1: 188,088,995 (GRCm39) |
I317F |
probably damaging |
Het |
| Usp1 |
T |
C |
4: 98,822,855 (GRCm39) |
V723A |
probably benign |
Het |
| Usp34 |
T |
G |
11: 23,293,616 (GRCm39) |
L237V |
probably damaging |
Het |
| Vgf |
A |
T |
5: 137,061,140 (GRCm39) |
D434V |
probably damaging |
Het |
| Vmn1r179 |
A |
G |
7: 23,628,100 (GRCm39) |
N97S |
probably benign |
Het |
| Vps13a |
A |
G |
19: 16,687,751 (GRCm39) |
L899P |
possibly damaging |
Het |
| Vps33b |
A |
T |
7: 79,924,001 (GRCm39) |
I41F |
probably damaging |
Het |
| Zap70 |
A |
T |
1: 36,817,299 (GRCm39) |
H210L |
probably damaging |
Het |
| Zc3h8 |
T |
C |
2: 128,770,835 (GRCm39) |
D300G |
probably benign |
Het |
| Zfp958 |
C |
A |
8: 4,676,196 (GRCm39) |
H55N |
possibly damaging |
Het |
|
| Other mutations in Kirrel1 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL01310:Kirrel1
|
APN |
3 |
86,997,182 (GRCm39) |
missense |
probably benign |
0.22 |
|
IGL01865:Kirrel1
|
APN |
3 |
86,993,731 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01875:Kirrel1
|
APN |
3 |
87,003,037 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02337:Kirrel1
|
APN |
3 |
86,996,519 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL02724:Kirrel1
|
APN |
3 |
86,997,780 (GRCm39) |
nonsense |
probably null |
|
|
IGL02825:Kirrel1
|
APN |
3 |
86,996,595 (GRCm39) |
splice site |
probably benign |
|
|
IGL02826:Kirrel1
|
APN |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03102:Kirrel1
|
APN |
3 |
86,990,807 (GRCm39) |
missense |
probably damaging |
0.98 |
|
D4043:Kirrel1
|
UTSW |
3 |
86,990,510 (GRCm39) |
missense |
probably benign |
0.02 |
|
R0360:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0364:Kirrel1
|
UTSW |
3 |
86,997,106 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0421:Kirrel1
|
UTSW |
3 |
86,990,914 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R0503:Kirrel1
|
UTSW |
3 |
87,005,109 (GRCm39) |
missense |
probably benign |
0.20 |
|
R1112:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1116:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1144:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1147:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1190:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1226:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1501:Kirrel1
|
UTSW |
3 |
86,997,779 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1538:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1546:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1628:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1630:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1631:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1664:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1671:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1695:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1769:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1807:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1808:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1840:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R1995:Kirrel1
|
UTSW |
3 |
87,003,093 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R2014:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2086:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2108:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2354:Kirrel1
|
UTSW |
3 |
86,995,792 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R2407:Kirrel1
|
UTSW |
3 |
86,992,150 (GRCm39) |
missense |
probably benign |
0.03 |
|
R2904:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2905:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2958:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2959:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2960:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R2961:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3026:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3028:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3034:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R3149:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3195:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3196:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3499:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3699:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3720:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3721:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3788:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3793:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3876:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3877:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3901:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3910:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3911:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3912:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3913:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3930:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R3931:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4022:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4067:Kirrel1
|
UTSW |
3 |
86,995,774 (GRCm39) |
nonsense |
probably null |
|
|
R4077:Kirrel1
|
UTSW |
3 |
86,992,387 (GRCm39) |
critical splice donor site |
probably null |
|
|
R4198:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4328:Kirrel1
|
UTSW |
3 |
86,992,081 (GRCm39) |
intron |
probably benign |
|
|
R4355:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4363:Kirrel1
|
UTSW |
3 |
86,997,792 (GRCm39) |
nonsense |
probably null |
|
|
R4378:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4386:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4460:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4468:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4469:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4650:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4652:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4734:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4748:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R4749:Kirrel1
|
UTSW |
3 |
86,996,458 (GRCm39) |
missense |
probably null |
0.46 |
|
R5534:Kirrel1
|
UTSW |
3 |
86,997,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5604:Kirrel1
|
UTSW |
3 |
86,996,462 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
R7199:Kirrel1
|
UTSW |
3 |
86,990,695 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7221:Kirrel1
|
UTSW |
3 |
86,993,704 (GRCm39) |
nonsense |
probably null |
|
|
R7284:Kirrel1
|
UTSW |
3 |
86,990,694 (GRCm39) |
missense |
probably benign |
0.02 |
|
R7332:Kirrel1
|
UTSW |
3 |
86,995,705 (GRCm39) |
missense |
probably benign |
0.14 |
|
R7369:Kirrel1
|
UTSW |
3 |
87,048,391 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7371:Kirrel1
|
UTSW |
3 |
86,995,729 (GRCm39) |
missense |
probably benign |
0.44 |
|
R7508:Kirrel1
|
UTSW |
3 |
86,990,746 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
R7566:Kirrel1
|
UTSW |
3 |
86,995,791 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7567:Kirrel1
|
UTSW |
3 |
87,002,988 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7621:Kirrel1
|
UTSW |
3 |
86,995,528 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R8030:Kirrel1
|
UTSW |
3 |
87,005,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8141:Kirrel1
|
UTSW |
3 |
86,993,735 (GRCm39) |
nonsense |
probably null |
|
|
R8261:Kirrel1
|
UTSW |
3 |
86,995,309 (GRCm39) |
intron |
probably benign |
|
|
R8477:Kirrel1
|
UTSW |
3 |
86,992,138 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
R8512:Kirrel1
|
UTSW |
3 |
86,995,534 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8954:Kirrel1
|
UTSW |
3 |
86,997,173 (GRCm39) |
missense |
probably benign |
0.25 |
|
R8987:Kirrel1
|
UTSW |
3 |
86,992,400 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9058:Kirrel1
|
UTSW |
3 |
86,992,442 (GRCm39) |
missense |
probably benign |
0.18 |
|
R9146:Kirrel1
|
UTSW |
3 |
87,003,015 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9311:Kirrel1
|
UTSW |
3 |
87,005,123 (GRCm39) |
missense |
probably benign |
0.29 |
|
R9527:Kirrel1
|
UTSW |
3 |
86,996,912 (GRCm39) |
nonsense |
probably null |
|
|
R9629:Kirrel1
|
UTSW |
3 |
87,003,025 (GRCm39) |
nonsense |
probably null |
|
|
Z1177:Kirrel1
|
UTSW |
3 |
86,991,182 (GRCm39) |
nonsense |
probably null |
|
|
| Predicted Primers |
PCR Primer
(F):5'- GGAGTTTTCGTCCCCTGTAC -3'
(R):5'- ATCTTGGGCTACAGGTGAGG -3'
Sequencing Primer
(F):5'- TGTACCCCAGGACCTTCGAAG -3'
(R):5'- GCTACAGGTGAGGGGATTG -3'
|
| Posted On |
2016-07-22 |
Incidental Mutation