Incidental Mutation 'IGL03030:Cobl'
| ID |
408412 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Cobl
|
| Ensembl Gene |
ENSMUSG00000020173 |
| Gene Name |
cordon-bleu WH2 repeat |
| Synonyms |
C530045F18Rik |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL03030
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
11 |
| Chromosomal Location |
12186676-12415022 bp(-) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
G to T
at 12204241 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Asparagine to Lysine
at position 813
(N813K)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000133470
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000046755]
[ENSMUST00000109650]
[ENSMUST00000109651]
[ENSMUST00000172919]
[ENSMUST00000172956]
[ENSMUST00000174874]
|
| AlphaFold |
Q5NBX1 |
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000046755
AA Change: N820K
PolyPhen 2
Score 0.795 (Sensitivity: 0.85; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000045693
Gene: ENSMUSG00000020173
AA Change: N820K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
14 |
30 |
N/A |
INTRINSIC |
|
Pfam:Cobl
|
144 |
235 |
2.2e-46 |
PFAM |
|
low complexity region
|
328 |
333 |
N/A |
INTRINSIC |
|
low complexity region
|
360 |
376 |
N/A |
INTRINSIC |
|
low complexity region
|
408 |
433 |
N/A |
INTRINSIC |
|
low complexity region
|
468 |
482 |
N/A |
INTRINSIC |
|
low complexity region
|
526 |
541 |
N/A |
INTRINSIC |
|
coiled coil region
|
564 |
589 |
N/A |
INTRINSIC |
|
WH2
|
1185 |
1205 |
1.32e0 |
SMART |
|
WH2
|
1225 |
1245 |
6.36e-3 |
SMART |
|
low complexity region
|
1276 |
1296 |
N/A |
INTRINSIC |
|
WH2
|
1313 |
1333 |
3.91e-3 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000109650
AA Change: N738K
PolyPhen 2
Score 0.551 (Sensitivity: 0.88; Specificity: 0.91)
|
| SMART Domains |
Protein: ENSMUSP00000105277
Gene: ENSMUSG00000020173
AA Change: N738K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
14 |
30 |
N/A |
INTRINSIC |
|
Pfam:Cobl
|
182 |
260 |
1.6e-40 |
PFAM |
|
low complexity region
|
303 |
308 |
N/A |
INTRINSIC |
|
low complexity region
|
335 |
351 |
N/A |
INTRINSIC |
|
low complexity region
|
386 |
400 |
N/A |
INTRINSIC |
|
low complexity region
|
444 |
459 |
N/A |
INTRINSIC |
|
coiled coil region
|
482 |
507 |
N/A |
INTRINSIC |
|
WH2
|
1103 |
1123 |
1.32e0 |
SMART |
|
WH2
|
1143 |
1163 |
6.36e-3 |
SMART |
|
low complexity region
|
1194 |
1214 |
N/A |
INTRINSIC |
|
WH2
|
1231 |
1251 |
3.91e-3 |
SMART |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000109651
AA Change: N795K
PolyPhen 2
Score 0.485 (Sensitivity: 0.88; Specificity: 0.90)
|
| SMART Domains |
Protein: ENSMUSP00000105278
Gene: ENSMUSG00000020173
AA Change: N795K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
14 |
30 |
N/A |
INTRINSIC |
|
Pfam:Cobl
|
182 |
260 |
1.2e-40 |
PFAM |
|
low complexity region
|
303 |
308 |
N/A |
INTRINSIC |
|
low complexity region
|
335 |
351 |
N/A |
INTRINSIC |
|
low complexity region
|
383 |
408 |
N/A |
INTRINSIC |
|
low complexity region
|
443 |
457 |
N/A |
INTRINSIC |
|
low complexity region
|
501 |
516 |
N/A |
INTRINSIC |
|
coiled coil region
|
539 |
564 |
N/A |
INTRINSIC |
|
WH2
|
1160 |
1180 |
1.32e0 |
SMART |
|
WH2
|
1200 |
1220 |
6.36e-3 |
SMART |
|
low complexity region
|
1251 |
1271 |
N/A |
INTRINSIC |
|
WH2
|
1288 |
1308 |
3.91e-3 |
SMART |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172919
|
| SMART Domains |
Protein: ENSMUSP00000133669
Gene: ENSMUSG00000020173
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
14 |
30 |
N/A |
INTRINSIC |
|
Pfam:Cobl
|
182 |
260 |
2.6e-41 |
PFAM |
|
low complexity region
|
328 |
333 |
N/A |
INTRINSIC |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000172956
|
| SMART Domains |
Protein: ENSMUSP00000134372
Gene: ENSMUSG00000020173
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
14 |
30 |
N/A |
INTRINSIC |
|
Pfam:Cobl
|
182 |
260 |
2.4e-41 |
PFAM |
|
low complexity region
|
303 |
308 |
N/A |
INTRINSIC |
|
low complexity region
|
335 |
351 |
N/A |
INTRINSIC |
|
| Predicted Effect |
possibly damaging
Transcript: ENSMUST00000174874
AA Change: N813K
PolyPhen 2
Score 0.795 (Sensitivity: 0.85; Specificity: 0.93)
|
| SMART Domains |
Protein: ENSMUSP00000133470
Gene: ENSMUSG00000020173
AA Change: N813K
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
6 |
23 |
N/A |
INTRINSIC |
|
Pfam:Cobl
|
175 |
253 |
1.2e-40 |
PFAM |
|
low complexity region
|
321 |
326 |
N/A |
INTRINSIC |
|
low complexity region
|
353 |
369 |
N/A |
INTRINSIC |
|
low complexity region
|
401 |
426 |
N/A |
INTRINSIC |
|
low complexity region
|
461 |
475 |
N/A |
INTRINSIC |
|
low complexity region
|
519 |
534 |
N/A |
INTRINSIC |
|
coiled coil region
|
557 |
582 |
N/A |
INTRINSIC |
|
WH2
|
1178 |
1198 |
1.32e0 |
SMART |
|
WH2
|
1218 |
1238 |
6.36e-3 |
SMART |
|
low complexity region
|
1269 |
1289 |
N/A |
INTRINSIC |
|
WH2
|
1306 |
1326 |
3.91e-3 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| MGI Phenotype |
FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] This gene encodes a protein that contains WH2 domains (WASP, Wiskott-Aldrich syndrome protein, homology domain-2) that interact with actin. The encoded actin regulator protein is required for growth and assembly of brush border microvilli that play a role in maintaining intestinal homeostasis. A similar protein in mouse functions in midbrain neural tube closure. A pseudogene of this gene is located on chromosome X. [provided by RefSeq, Oct 2016]
PHENOTYPE: Animals homozygous for this mutation do not display a phenotype. However, the allele exacerbates the neural tube defects seen in the loop tail mouse. [provided by MGI curators]
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 68 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| 4931406B18Rik |
A |
G |
7: 43,145,057 (GRCm39) |
V367A |
possibly damaging |
Het |
| Abcb5 |
A |
T |
12: 118,904,104 (GRCm39) |
S200R |
possibly damaging |
Het |
| Adam29 |
T |
C |
8: 56,326,100 (GRCm39) |
D118G |
probably damaging |
Het |
| Adh4 |
A |
G |
3: 138,134,906 (GRCm39) |
D360G |
probably benign |
Het |
| Ankle2 |
A |
G |
5: 110,399,476 (GRCm39) |
Q611R |
possibly damaging |
Het |
| Ankra2 |
C |
T |
13: 98,409,881 (GRCm39) |
|
probably benign |
Het |
| Ap1g2 |
T |
A |
14: 55,343,504 (GRCm39) |
I28F |
probably damaging |
Het |
| Baz2a |
C |
T |
10: 127,961,015 (GRCm39) |
T1608I |
possibly damaging |
Het |
| Cacnb4 |
T |
C |
2: 52,364,894 (GRCm39) |
D123G |
probably damaging |
Het |
| Cage1 |
G |
A |
13: 38,212,123 (GRCm39) |
T51M |
probably benign |
Het |
| Ccdc63 |
A |
G |
5: 122,260,876 (GRCm39) |
V216A |
probably benign |
Het |
| Ccnd2 |
A |
G |
6: 127,125,841 (GRCm39) |
V65A |
probably damaging |
Het |
| Cfap20dc |
A |
G |
14: 8,511,113 (GRCm38) |
S434P |
probably damaging |
Het |
| Chd3 |
T |
A |
11: 69,245,230 (GRCm39) |
T1163S |
possibly damaging |
Het |
| Cmbl |
A |
G |
15: 31,589,823 (GRCm39) |
|
probably benign |
Het |
| Cog5 |
G |
A |
12: 31,840,921 (GRCm39) |
V249M |
probably damaging |
Het |
| Cps1 |
A |
G |
1: 67,182,080 (GRCm39) |
N98S |
probably damaging |
Het |
| Cracd |
A |
G |
5: 77,005,463 (GRCm39) |
D608G |
unknown |
Het |
| D630045J12Rik |
A |
T |
6: 38,126,648 (GRCm39) |
I1454N |
probably damaging |
Het |
| Elmo2 |
A |
G |
2: 165,136,237 (GRCm39) |
V603A |
possibly damaging |
Het |
| F12 |
A |
G |
13: 55,569,332 (GRCm39) |
|
probably benign |
Het |
| Ficd |
G |
A |
5: 113,874,990 (GRCm39) |
V20I |
probably benign |
Het |
| Gatad2b |
G |
T |
3: 90,249,244 (GRCm39) |
G94V |
probably benign |
Het |
| Gm4845 |
G |
A |
1: 141,184,403 (GRCm39) |
|
noncoding transcript |
Het |
| Hrnr |
G |
A |
3: 93,227,908 (GRCm39) |
V9I |
possibly damaging |
Het |
| Kifc3 |
A |
G |
8: 95,829,040 (GRCm39) |
S584P |
probably damaging |
Het |
| Klk1b24 |
C |
A |
7: 43,840,790 (GRCm39) |
Q73K |
probably benign |
Het |
| Lrp10 |
C |
A |
14: 54,706,619 (GRCm39) |
N518K |
possibly damaging |
Het |
| Lsr |
A |
G |
7: 30,658,706 (GRCm39) |
V247A |
possibly damaging |
Het |
| Mfsd6 |
A |
T |
1: 52,748,862 (GRCm39) |
M1K |
probably null |
Het |
| Mprip |
T |
A |
11: 59,631,941 (GRCm39) |
|
probably null |
Het |
| Myo3b |
G |
T |
2: 70,257,160 (GRCm39) |
|
probably benign |
Het |
| Oprd1 |
A |
G |
4: 131,844,696 (GRCm39) |
F104S |
possibly damaging |
Het |
| Or1l4 |
T |
C |
2: 37,091,883 (GRCm39) |
V210A |
probably benign |
Het |
| Or2g1 |
T |
A |
17: 38,107,162 (GRCm39) |
Y276N |
probably damaging |
Het |
| Or4b1d |
A |
T |
2: 89,969,006 (GRCm39) |
I159N |
possibly damaging |
Het |
| Or5ar1 |
T |
C |
2: 85,671,416 (GRCm39) |
T240A |
probably damaging |
Het |
| Or5b109 |
C |
T |
19: 13,212,418 (GRCm39) |
S268L |
probably damaging |
Het |
| Palb2 |
A |
G |
7: 121,712,479 (GRCm39) |
V591A |
probably damaging |
Het |
| Pcdhb18 |
A |
T |
18: 37,623,786 (GRCm39) |
D372V |
probably damaging |
Het |
| Phc3 |
A |
G |
3: 30,991,002 (GRCm39) |
V405A |
probably damaging |
Het |
| Phf20l1 |
A |
T |
15: 66,513,796 (GRCm39) |
|
probably benign |
Het |
| Pik3ip1 |
A |
G |
11: 3,283,259 (GRCm39) |
K57E |
possibly damaging |
Het |
| Pkhd1l1 |
G |
A |
15: 44,455,372 (GRCm39) |
M4044I |
probably benign |
Het |
| Pkhd1l1 |
T |
C |
15: 44,460,298 (GRCm39) |
V4169A |
probably benign |
Het |
| Pklr |
A |
T |
3: 89,049,963 (GRCm39) |
I313F |
probably damaging |
Het |
| Plxna4 |
T |
A |
6: 32,179,160 (GRCm39) |
T952S |
probably benign |
Het |
| Pop4 |
A |
T |
7: 37,962,730 (GRCm39) |
I178N |
probably damaging |
Het |
| Prorp |
A |
G |
12: 55,351,429 (GRCm39) |
D246G |
probably damaging |
Het |
| Prss40 |
A |
C |
1: 34,597,182 (GRCm39) |
V122G |
probably damaging |
Het |
| Rapgef2 |
C |
A |
3: 78,981,614 (GRCm39) |
|
probably null |
Het |
| Rbm19 |
A |
G |
5: 120,269,311 (GRCm39) |
D538G |
probably damaging |
Het |
| Rnf44 |
G |
A |
13: 54,829,803 (GRCm39) |
R312* |
probably null |
Het |
| Rock1 |
T |
C |
18: 10,070,215 (GRCm39) |
|
probably benign |
Het |
| Rrp1b |
A |
G |
17: 32,275,875 (GRCm39) |
E474G |
probably damaging |
Het |
| Ryr2 |
T |
A |
13: 11,699,365 (GRCm39) |
I2959F |
probably damaging |
Het |
| Sidt2 |
A |
G |
9: 45,850,803 (GRCm39) |
S801P |
probably damaging |
Het |
| Skint6 |
T |
C |
4: 112,870,153 (GRCm39) |
I602V |
probably benign |
Het |
| Slc6a19 |
C |
A |
13: 73,848,590 (GRCm39) |
V55L |
probably damaging |
Het |
| Smarca4 |
C |
T |
9: 21,547,132 (GRCm39) |
T219I |
probably benign |
Het |
| Trappc11 |
C |
A |
8: 47,966,964 (GRCm39) |
V440F |
probably damaging |
Het |
| Vmn1r236 |
G |
A |
17: 21,507,108 (GRCm39) |
W75* |
probably null |
Het |
| Vmn2r52 |
A |
G |
7: 9,892,799 (GRCm39) |
F780S |
probably benign |
Het |
| Vmn2r82 |
G |
T |
10: 79,217,149 (GRCm39) |
A494S |
possibly damaging |
Het |
| Vwa3b |
A |
T |
1: 37,084,049 (GRCm39) |
K74M |
probably damaging |
Het |
| Wrn |
T |
A |
8: 33,738,989 (GRCm39) |
I1037F |
possibly damaging |
Het |
| Zfp13 |
T |
C |
17: 23,799,819 (GRCm39) |
T82A |
probably benign |
Het |
| Zfp82 |
T |
C |
7: 29,756,890 (GRCm39) |
E64G |
probably benign |
Het |
|
| Other mutations in Cobl |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00338:Cobl
|
APN |
11 |
12,325,813 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
IGL00698:Cobl
|
APN |
11 |
12,203,722 (GRCm39) |
missense |
probably benign |
0.41 |
|
IGL00772:Cobl
|
APN |
11 |
12,216,985 (GRCm39) |
missense |
probably benign |
0.02 |
|
IGL00922:Cobl
|
APN |
11 |
12,204,866 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL00985:Cobl
|
APN |
11 |
12,204,843 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL01641:Cobl
|
APN |
11 |
12,259,641 (GRCm39) |
nonsense |
probably null |
|
|
IGL01722:Cobl
|
APN |
11 |
12,203,987 (GRCm39) |
missense |
probably benign |
0.00 |
|
IGL01734:Cobl
|
APN |
11 |
12,204,980 (GRCm39) |
splice site |
probably benign |
|
|
IGL01924:Cobl
|
APN |
11 |
12,204,596 (GRCm39) |
missense |
probably benign |
0.30 |
|
IGL02105:Cobl
|
APN |
11 |
12,199,651 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02326:Cobl
|
APN |
11 |
12,336,712 (GRCm39) |
missense |
possibly damaging |
0.69 |
|
IGL02342:Cobl
|
APN |
11 |
12,203,672 (GRCm39) |
missense |
possibly damaging |
0.64 |
|
IGL02426:Cobl
|
APN |
11 |
12,204,351 (GRCm39) |
nonsense |
probably null |
|
|
IGL02754:Cobl
|
APN |
11 |
12,204,370 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02754:Cobl
|
APN |
11 |
12,204,371 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02811:Cobl
|
APN |
11 |
12,203,285 (GRCm39) |
missense |
possibly damaging |
0.56 |
|
IGL02859:Cobl
|
APN |
11 |
12,319,602 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL02999:Cobl
|
APN |
11 |
12,293,869 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL03191:Cobl
|
APN |
11 |
12,203,364 (GRCm39) |
missense |
probably benign |
0.00 |
|
PIT4418001:Cobl
|
UTSW |
11 |
12,206,240 (GRCm39) |
missense |
possibly damaging |
0.79 |
|
PIT4480001:Cobl
|
UTSW |
11 |
12,203,592 (GRCm39) |
missense |
probably benign |
|
|
PIT4495001:Cobl
|
UTSW |
11 |
12,204,596 (GRCm39) |
missense |
probably benign |
0.00 |
|
R0031:Cobl
|
UTSW |
11 |
12,204,945 (GRCm39) |
missense |
probably benign |
0.36 |
|
R0241:Cobl
|
UTSW |
11 |
12,204,524 (GRCm39) |
missense |
probably benign |
0.25 |
|
R0241:Cobl
|
UTSW |
11 |
12,204,524 (GRCm39) |
missense |
probably benign |
0.25 |
|
R0322:Cobl
|
UTSW |
11 |
12,217,072 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0597:Cobl
|
UTSW |
11 |
12,204,699 (GRCm39) |
missense |
probably benign |
0.24 |
|
R0733:Cobl
|
UTSW |
11 |
12,315,167 (GRCm39) |
missense |
probably benign |
0.31 |
|
R0734:Cobl
|
UTSW |
11 |
12,325,971 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0784:Cobl
|
UTSW |
11 |
12,216,843 (GRCm39) |
splice site |
probably benign |
|
|
R0884:Cobl
|
UTSW |
11 |
12,325,908 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R1065:Cobl
|
UTSW |
11 |
12,204,327 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R1331:Cobl
|
UTSW |
11 |
12,325,853 (GRCm39) |
missense |
probably damaging |
0.96 |
|
R1892:Cobl
|
UTSW |
11 |
12,203,258 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R2847:Cobl
|
UTSW |
11 |
12,328,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2848:Cobl
|
UTSW |
11 |
12,328,342 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3407:Cobl
|
UTSW |
11 |
12,325,830 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4627:Cobl
|
UTSW |
11 |
12,201,093 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4662:Cobl
|
UTSW |
11 |
12,203,672 (GRCm39) |
missense |
probably benign |
0.08 |
|
R4677:Cobl
|
UTSW |
11 |
12,336,665 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4844:Cobl
|
UTSW |
11 |
12,204,740 (GRCm39) |
missense |
probably benign |
0.10 |
|
R4942:Cobl
|
UTSW |
11 |
12,204,185 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5158:Cobl
|
UTSW |
11 |
12,206,198 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R5195:Cobl
|
UTSW |
11 |
12,203,565 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5255:Cobl
|
UTSW |
11 |
12,325,825 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5588:Cobl
|
UTSW |
11 |
12,293,886 (GRCm39) |
nonsense |
probably null |
|
|
R5637:Cobl
|
UTSW |
11 |
12,246,531 (GRCm39) |
intron |
probably benign |
|
|
R5643:Cobl
|
UTSW |
11 |
12,256,948 (GRCm39) |
splice site |
probably benign |
|
|
R5749:Cobl
|
UTSW |
11 |
12,216,965 (GRCm39) |
missense |
possibly damaging |
0.86 |
|
R5953:Cobl
|
UTSW |
11 |
12,206,220 (GRCm39) |
missense |
probably benign |
0.00 |
|
R6000:Cobl
|
UTSW |
11 |
12,319,684 (GRCm39) |
missense |
probably benign |
0.08 |
|
R6373:Cobl
|
UTSW |
11 |
12,203,118 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7034:Cobl
|
UTSW |
11 |
12,204,177 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7071:Cobl
|
UTSW |
11 |
12,204,795 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7077:Cobl
|
UTSW |
11 |
12,203,441 (GRCm39) |
missense |
probably benign |
0.04 |
|
R7078:Cobl
|
UTSW |
11 |
12,328,271 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7099:Cobl
|
UTSW |
11 |
12,246,540 (GRCm39) |
missense |
|
|
|
R7153:Cobl
|
UTSW |
11 |
12,204,128 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7448:Cobl
|
UTSW |
11 |
12,206,225 (GRCm39) |
missense |
possibly damaging |
0.46 |
|
R7519:Cobl
|
UTSW |
11 |
12,203,124 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7767:Cobl
|
UTSW |
11 |
12,362,117 (GRCm39) |
start gained |
probably benign |
|
|
R7772:Cobl
|
UTSW |
11 |
12,204,488 (GRCm39) |
missense |
probably benign |
0.29 |
|
R7841:Cobl
|
UTSW |
11 |
12,203,324 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R7845:Cobl
|
UTSW |
11 |
12,315,139 (GRCm39) |
missense |
probably benign |
0.35 |
|
R8026:Cobl
|
UTSW |
11 |
12,203,459 (GRCm39) |
missense |
probably benign |
0.01 |
|
R8118:Cobl
|
UTSW |
11 |
12,204,834 (GRCm39) |
missense |
probably benign |
0.03 |
|
R8192:Cobl
|
UTSW |
11 |
12,199,745 (GRCm39) |
missense |
probably benign |
0.07 |
|
R8320:Cobl
|
UTSW |
11 |
12,217,001 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8338:Cobl
|
UTSW |
11 |
12,203,696 (GRCm39) |
missense |
probably benign |
0.41 |
|
R9319:Cobl
|
UTSW |
11 |
12,203,648 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9497:Cobl
|
UTSW |
11 |
12,203,501 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9501:Cobl
|
UTSW |
11 |
12,328,235 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
Z1176:Cobl
|
UTSW |
11 |
12,325,827 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Cobl
|
UTSW |
11 |
12,319,645 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1176:Cobl
|
UTSW |
11 |
12,203,433 (GRCm39) |
missense |
probably benign |
0.02 |
|
| Posted On |
2016-08-02 |
Incidental Mutation