Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03144:Unc79'

410809

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Unc79

Ensembl Gene

ENSMUSG00000021198

Gene Name

unc-79 homolog

Synonyms

9030205A07Rik, Mlca3

Accession Numbers

Essential gene?

Essential (E-score: 1.000) question?

Stock #

IGL03144

Quality Score

Status

Chromosome

Chromosomal Location

102915118-103150324 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to C at 103008401 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Isoleucine to Threonine at position 256 (I256T)

Ref Sequence

ENSEMBL: ENSMUSP00000136332 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000085079] [ENSMUST00000101099] [ENSMUST00000178001] [ENSMUST00000178076] [ENSMUST00000179002]

AlphaFold

Q0KK59

Predicted Effect

possibly damaging
Transcript: ENSMUST00000085079
AA Change: I132T

PolyPhen 2 Score 0.518 (Sensitivity: 0.88; Specificity: 0.90)

SMART Domains

Protein: ENSMUSP00000082156
Gene: ENSMUSG00000021198
AA Change: I132T

Domain	Start	End	E-Value	Type
Pfam:UNC-79	1	469	3.1e-223	PFAM
low complexity region	732	737	N/A	INTRINSIC
low complexity region	846	862	N/A	INTRINSIC
low complexity region	968	977	N/A	INTRINSIC
low complexity region	1114	1125	N/A	INTRINSIC
low complexity region	1313	1325	N/A	INTRINSIC
low complexity region	1428	1440	N/A	INTRINSIC
low complexity region	1471	1476	N/A	INTRINSIC
low complexity region	1477	1489	N/A	INTRINSIC
low complexity region	1490	1504	N/A	INTRINSIC
low complexity region	1541	1556	N/A	INTRINSIC
low complexity region	1861	1870	N/A	INTRINSIC
low complexity region	2237	2246	N/A	INTRINSIC

Predicted Effect

possibly damaging
Transcript: ENSMUST00000101099
AA Change: I309T

PolyPhen 2 Score 0.931 (Sensitivity: 0.81; Specificity: 0.94)

SMART Domains

Protein: ENSMUSP00000098659
Gene: ENSMUSG00000021198
AA Change: I309T

Domain	Start	End	E-Value	Type
Pfam:UNC-79	113	646	1.2e-226	PFAM
low complexity region	909	914	N/A	INTRINSIC
low complexity region	1023	1039	N/A	INTRINSIC
low complexity region	1145	1154	N/A	INTRINSIC
low complexity region	1291	1302	N/A	INTRINSIC
low complexity region	1490	1502	N/A	INTRINSIC
low complexity region	1605	1617	N/A	INTRINSIC
low complexity region	1648	1653	N/A	INTRINSIC
low complexity region	1654	1666	N/A	INTRINSIC
low complexity region	1667	1681	N/A	INTRINSIC
low complexity region	1718	1733	N/A	INTRINSIC
low complexity region	1999	2008	N/A	INTRINSIC
low complexity region	2375	2384	N/A	INTRINSIC

Predicted Effect

probably benign
Transcript: ENSMUST00000178001
AA Change: I87T

PolyPhen 2 Score 0.004 (Sensitivity: 0.98; Specificity: 0.59)

SMART Domains

Protein: ENSMUSP00000137132
Gene: ENSMUSG00000021198
AA Change: I87T

Domain	Start	End	E-Value	Type
Pfam:UNC-79	1	80	1.2e-30	PFAM
Pfam:UNC-79	78	188	2.1e-53	PFAM

Predicted Effect

probably damaging
Transcript: ENSMUST00000178076
AA Change: I113T

PolyPhen 2 Score 0.990 (Sensitivity: 0.72; Specificity: 0.97)

SMART Domains

Protein: ENSMUSP00000136888
Gene: ENSMUSG00000021198
AA Change: I113T

Domain	Start	End	E-Value	Type
Pfam:UNC-79	1	450	4.2e-213	PFAM
low complexity region	713	718	N/A	INTRINSIC
low complexity region	827	843	N/A	INTRINSIC
low complexity region	949	958	N/A	INTRINSIC
low complexity region	1117	1128	N/A	INTRINSIC
low complexity region	1316	1328	N/A	INTRINSIC
low complexity region	1431	1443	N/A	INTRINSIC
low complexity region	1474	1479	N/A	INTRINSIC
low complexity region	1480	1492	N/A	INTRINSIC
low complexity region	1493	1507	N/A	INTRINSIC
low complexity region	1544	1559	N/A	INTRINSIC
low complexity region	1864	1873	N/A	INTRINSIC
low complexity region	2240	2249	N/A	INTRINSIC

Predicted Effect

probably damaging
Transcript: ENSMUST00000179002
AA Change: I256T

PolyPhen 2 Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)

SMART Domains

Protein: ENSMUSP00000136332
Gene: ENSMUSG00000021198
AA Change: I256T

Domain	Start	End	E-Value	Type
Pfam:UNC-79	60	593	1.3e-226	PFAM
low complexity region	856	861	N/A	INTRINSIC
low complexity region	970	986	N/A	INTRINSIC
low complexity region	1092	1101	N/A	INTRINSIC
low complexity region	1260	1271	N/A	INTRINSIC
low complexity region	1509	1521	N/A	INTRINSIC
low complexity region	1624	1636	N/A	INTRINSIC
low complexity region	1667	1672	N/A	INTRINSIC
low complexity region	1673	1685	N/A	INTRINSIC
low complexity region	1686	1700	N/A	INTRINSIC
low complexity region	1737	1752	N/A	INTRINSIC
low complexity region	2057	2066	N/A	INTRINSIC
low complexity region	2433	2442	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

MGI Phenotype

FUNCTION: [Summary is not available for the mouse gene. This summary is for the human ortholog.] The NALCN channel is responsible for Na(+) leak currents. The protein encoded by this gene, along with UNC80, is an accessory subunit of the NALCN channel that contributes to the Ca(2+) sensitivity of the channel. [provided by RefSeq, Sep 2016]
PHENOTYPE: Homozygous mutation results in lethality within the first week after birth, mostly at P0 or P1. Pups fail to nurse and have no milk in stomachs resulting in weakness, inactivity and no weight gain. [provided by MGI curators]

Allele List at MGI

All alleles(2) : Targeted, knock-out(1) Chemically induced(1)

Other mutations in this stock

Total: 49 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Abca3	C	A	17: 24,600,938 (GRCm39)	Q451K	probably benign	Het
Acly	A	T	11: 100,405,909 (GRCm39)	D294E	possibly damaging	Het
Arid3a	C	T	10: 79,782,316 (GRCm39)		probably benign	Het
Ascc3	T	C	10: 50,643,539 (GRCm39)	V1830A	probably benign	Het
Atp6v1b1	T	C	6: 83,735,333 (GRCm39)	V467A	probably benign	Het
Ccdc171	A	T	4: 83,736,327 (GRCm39)	I1233L	probably damaging	Het
Ccdc74a	C	A	16: 17,466,730 (GRCm39)	Q146K	possibly damaging	Het
Cdh26	A	G	2: 178,109,967 (GRCm39)	D420G	probably damaging	Het
Ceacam20	T	C	7: 19,705,444 (GRCm39)	V145A	possibly damaging	Het
Cmya5	C	A	13: 93,227,376 (GRCm39)	A2571S	probably damaging	Het
Cog2	T	C	8: 125,267,763 (GRCm39)	S360P	probably damaging	Het
Col26a1	G	T	5: 136,794,202 (GRCm39)	T132N	probably damaging	Het
Col6a2	T	A	10: 76,450,259 (GRCm39)	H224L	probably benign	Het
Cpm	C	T	10: 117,519,319 (GRCm39)	S409L	probably benign	Het
Dock4	G	T	12: 40,742,906 (GRCm39)		probably benign	Het
Dpy19l2	T	A	9: 24,557,603 (GRCm39)	N391Y	possibly damaging	Het
Exosc9	G	A	3: 36,608,284 (GRCm39)	G126D	probably damaging	Het
Eya3	T	C	4: 132,420,453 (GRCm39)	S256P	probably benign	Het
Fat3	T	C	9: 16,286,541 (GRCm39)	D994G	probably damaging	Het
Fat4	A	G	3: 39,011,008 (GRCm39)	Q2036R	possibly damaging	Het
Fryl	T	C	5: 73,258,798 (GRCm39)	Q662R	probably null	Het
Gm13271	A	G	4: 88,673,636 (GRCm39)	R178G	probably benign	Het
Gpr165	T	A	X: 95,760,560 (GRCm39)	L279Q	probably damaging	Het
Htr1b	A	G	9: 81,513,998 (GRCm39)	L203P	probably damaging	Het
Kcnb2	T	C	1: 15,780,112 (GRCm39)	L328P	probably damaging	Het
Klhl26	C	T	8: 70,905,214 (GRCm39)	R198H	probably damaging	Het
Nhsl2	A	G	X: 101,123,115 (GRCm39)	R973G	possibly damaging	Het
Nmi	A	T	2: 51,842,546 (GRCm39)	F182Y	probably damaging	Het
Nop2	T	A	6: 125,114,475 (GRCm39)		probably null	Het
Nrn1	C	A	13: 36,914,080 (GRCm39)		probably null	Het
Ooep	G	T	9: 78,285,289 (GRCm39)	A109E	possibly damaging	Het
Or1j21	A	G	2: 36,684,093 (GRCm39)	T282A	probably benign	Het
Pan3	T	C	5: 147,387,591 (GRCm39)		probably benign	Het
Pcdhb6	A	G	18: 37,467,459 (GRCm39)	N127D	probably damaging	Het
Rabgap1	G	A	2: 37,430,544 (GRCm39)	R695H	probably damaging	Het
Rxrg	G	A	1: 167,426,327 (GRCm39)	G3R	possibly damaging	Het
Slc17a3	T	C	13: 24,030,423 (GRCm39)	M178T	probably benign	Het
Slc39a8	A	G	3: 135,589,971 (GRCm39)	E287G	probably benign	Het
Slc44a5	G	T	3: 153,949,177 (GRCm39)	D217Y	possibly damaging	Het
Slc4a10	G	T	2: 62,080,810 (GRCm39)	V346L	probably benign	Het
Slc9a4	T	C	1: 40,651,362 (GRCm39)	Y547H	probably damaging	Het
St6galnac3	A	C	3: 152,911,164 (GRCm39)	Y266D	probably damaging	Het
Stard6	A	T	18: 70,609,182 (GRCm39)	Y3F	possibly damaging	Het
Stk25	C	A	1: 93,556,858 (GRCm39)	L53F	probably damaging	Het
Tep1	A	T	14: 51,081,474 (GRCm39)		probably benign	Het
Tmem151a	T	A	19: 5,135,400 (GRCm39)	M1L	probably benign	Het
Trim10	T	C	17: 37,187,740 (GRCm39)	S319P	probably damaging	Het
Trmt44	G	T	5: 35,721,766 (GRCm39)	P466T	probably benign	Het
Vmn2r125	G	T	4: 156,702,314 (GRCm39)	L33F	possibly damaging	Het

Other mutations in Unc79

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00718:Unc79	APN	12	103,135,906 (GRCm39)	missense	possibly damaging	0.68
IGL00835:Unc79	APN	12	103,108,149 (GRCm39)	splice site	probably benign
IGL00917:Unc79	APN	12	103,054,766 (GRCm39)	missense	possibly damaging	0.53
IGL01012:Unc79	APN	12	103,078,714 (GRCm39)	missense	probably damaging	1.00
IGL01121:Unc79	APN	12	103,131,890 (GRCm39)	missense	probably damaging	0.99
IGL01303:Unc79	APN	12	103,128,126 (GRCm39)	missense	possibly damaging	0.94
IGL01305:Unc79	APN	12	102,968,130 (GRCm39)	missense	probably damaging	0.99
IGL01315:Unc79	APN	12	103,054,780 (GRCm39)	missense	possibly damaging	0.66
IGL01388:Unc79	APN	12	103,136,018 (GRCm39)	splice site	probably benign
IGL01415:Unc79	APN	12	103,074,944 (GRCm39)	missense	probably damaging	1.00
IGL01447:Unc79	APN	12	103,045,177 (GRCm39)	missense	probably damaging	1.00
IGL01655:Unc79	APN	12	103,134,546 (GRCm39)	missense	probably benign	0.00
IGL01662:Unc79	APN	12	103,115,279 (GRCm39)	missense	possibly damaging	0.92
IGL01728:Unc79	APN	12	103,131,943 (GRCm39)	missense	probably damaging	0.98
IGL01767:Unc79	APN	12	103,108,256 (GRCm39)	missense	probably damaging	1.00
IGL02080:Unc79	APN	12	102,968,234 (GRCm39)	missense	probably damaging	1.00
IGL02115:Unc79	APN	12	102,964,933 (GRCm39)	missense	probably damaging	1.00
IGL02176:Unc79	APN	12	102,965,006 (GRCm39)	splice site	probably null
IGL02186:Unc79	APN	12	102,977,542 (GRCm39)	missense	probably benign	0.04
IGL02205:Unc79	APN	12	103,045,260 (GRCm39)	missense	probably damaging	1.00
IGL02337:Unc79	APN	12	103,122,705 (GRCm39)	splice site	probably benign
IGL02498:Unc79	APN	12	103,137,837 (GRCm39)	missense	probably damaging	0.99
IGL02508:Unc79	APN	12	103,078,535 (GRCm39)	missense	probably damaging	0.97
IGL02508:Unc79	APN	12	103,078,277 (GRCm39)	splice site	probably benign
IGL02557:Unc79	APN	12	103,148,418 (GRCm39)	splice site	probably benign
IGL02589:Unc79	APN	12	103,139,755 (GRCm39)	missense	probably damaging	1.00
IGL02611:Unc79	APN	12	103,131,967 (GRCm39)	missense	probably damaging	0.97
IGL02728:Unc79	APN	12	103,088,688 (GRCm39)	missense	possibly damaging	0.53
IGL02827:Unc79	APN	12	103,041,105 (GRCm39)	missense	possibly damaging	0.88
IGL03028:Unc79	APN	12	103,139,785 (GRCm39)	missense	possibly damaging	0.83
IGL03229:Unc79	APN	12	103,100,798 (GRCm39)	missense	probably damaging	0.99
IGL03269:Unc79	APN	12	103,054,936 (GRCm39)	missense	probably damaging	1.00
IGL03325:Unc79	APN	12	103,135,869 (GRCm39)	missense	probably damaging	0.98
pencil-thin	UTSW	12	103,075,040 (GRCm39)	splice site	probably null
sweetpea	UTSW	12	103,025,777 (GRCm39)	missense	probably damaging	1.00
3-1:Unc79	UTSW	12	103,039,009 (GRCm39)	nonsense	probably null
ANU22:Unc79	UTSW	12	102,968,130 (GRCm39)	missense	probably damaging	0.99
R0046:Unc79	UTSW	12	103,091,940 (GRCm39)	missense	probably damaging	0.99
R0046:Unc79	UTSW	12	103,091,940 (GRCm39)	missense	probably damaging	0.99
R0067:Unc79	UTSW	12	103,025,777 (GRCm39)	missense	probably damaging	1.00
R0067:Unc79	UTSW	12	103,025,777 (GRCm39)	missense	probably damaging	1.00
R0107:Unc79	UTSW	12	103,100,784 (GRCm39)	missense	possibly damaging	0.70
R0110:Unc79	UTSW	12	103,045,329 (GRCm39)	critical splice donor site	probably null
R0128:Unc79	UTSW	12	103,054,693 (GRCm39)	splice site	probably benign
R0166:Unc79	UTSW	12	103,122,812 (GRCm39)	missense	probably damaging	1.00
R0208:Unc79	UTSW	12	103,058,286 (GRCm39)	missense	probably benign	0.00
R0211:Unc79	UTSW	12	103,039,051 (GRCm39)	missense	probably benign	0.01
R0211:Unc79	UTSW	12	103,039,051 (GRCm39)	missense	probably benign	0.01
R0218:Unc79	UTSW	12	103,075,040 (GRCm39)	splice site	probably null
R0244:Unc79	UTSW	12	103,079,150 (GRCm39)	missense	probably damaging	1.00
R0305:Unc79	UTSW	12	103,079,459 (GRCm39)	missense	probably benign	0.18
R0310:Unc79	UTSW	12	103,027,666 (GRCm39)	missense	probably damaging	1.00
R0325:Unc79	UTSW	12	103,137,903 (GRCm39)	missense	probably damaging	0.98
R0369:Unc79	UTSW	12	103,055,031 (GRCm39)	critical splice donor site	probably null
R0450:Unc79	UTSW	12	103,045,329 (GRCm39)	critical splice donor site	probably null
R0503:Unc79	UTSW	12	103,045,127 (GRCm39)	missense	probably benign	0.01
R0542:Unc79	UTSW	12	103,060,437 (GRCm39)	splice site	probably benign
R0845:Unc79	UTSW	12	103,139,703 (GRCm39)	splice site	probably benign
R0893:Unc79	UTSW	12	102,957,687 (GRCm39)	missense	probably damaging	1.00
R1078:Unc79	UTSW	12	103,041,112 (GRCm39)	missense	probably benign	0.03
R1148:Unc79	UTSW	12	103,078,926 (GRCm39)	missense	probably damaging	1.00
R1148:Unc79	UTSW	12	103,078,926 (GRCm39)	missense	probably damaging	1.00
R1159:Unc79	UTSW	12	103,013,311 (GRCm39)	splice site	probably benign
R1191:Unc79	UTSW	12	103,013,271 (GRCm39)	nonsense	probably null
R1307:Unc79	UTSW	12	103,036,335 (GRCm39)	missense	probably damaging	1.00
R1368:Unc79	UTSW	12	103,122,772 (GRCm39)	missense	probably damaging	1.00
R1476:Unc79	UTSW	12	103,149,784 (GRCm39)	missense	probably damaging	1.00
R1650:Unc79	UTSW	12	103,079,052 (GRCm39)	missense	possibly damaging	0.85
R1777:Unc79	UTSW	12	103,078,714 (GRCm39)	missense	probably damaging	1.00
R1796:Unc79	UTSW	12	103,109,005 (GRCm39)	missense	probably damaging	0.99
R1824:Unc79	UTSW	12	103,025,579 (GRCm39)	missense	probably damaging	1.00
R1830:Unc79	UTSW	12	103,100,737 (GRCm39)	missense	probably damaging	1.00
R1927:Unc79	UTSW	12	103,135,951 (GRCm39)	missense	probably damaging	1.00
R1958:Unc79	UTSW	12	103,041,178 (GRCm39)	missense	probably benign	0.19
R1958:Unc79	UTSW	12	102,957,621 (GRCm39)	missense	probably damaging	1.00
R1980:Unc79	UTSW	12	102,977,538 (GRCm39)	nonsense	probably null
R2019:Unc79	UTSW	12	103,137,830 (GRCm39)	critical splice acceptor site	probably null
R2290:Unc79	UTSW	12	103,112,625 (GRCm39)	missense	probably damaging	1.00
R2939:Unc79	UTSW	12	102,957,684 (GRCm39)	missense	probably damaging	1.00
R2962:Unc79	UTSW	12	103,061,378 (GRCm39)	missense	possibly damaging	0.72
R3176:Unc79	UTSW	12	103,079,476 (GRCm39)	missense	probably damaging	1.00
R3276:Unc79	UTSW	12	103,079,476 (GRCm39)	missense	probably damaging	1.00
R3683:Unc79	UTSW	12	103,041,062 (GRCm39)	missense	probably benign	0.00
R3684:Unc79	UTSW	12	103,041,062 (GRCm39)	missense	probably benign	0.00
R3686:Unc79	UTSW	12	103,054,920 (GRCm39)	missense	probably damaging	1.00
R3760:Unc79	UTSW	12	103,058,964 (GRCm39)	missense	probably damaging	1.00
R4031:Unc79	UTSW	12	103,039,018 (GRCm39)	missense	possibly damaging	0.46
R4039:Unc79	UTSW	12	103,041,208 (GRCm39)	missense	possibly damaging	0.88
R4110:Unc79	UTSW	12	103,025,629 (GRCm39)	missense	probably damaging	1.00
R4113:Unc79	UTSW	12	103,025,629 (GRCm39)	missense	probably damaging	1.00
R4159:Unc79	UTSW	12	103,036,512 (GRCm39)	intron	probably benign
R4273:Unc79	UTSW	12	103,088,612 (GRCm39)	missense	probably damaging	0.99
R4292:Unc79	UTSW	12	103,149,703 (GRCm39)	missense	probably damaging	0.99
R4334:Unc79	UTSW	12	103,045,233 (GRCm39)	missense	probably benign
R4513:Unc79	UTSW	12	102,988,019 (GRCm39)	missense	probably damaging	1.00
R4562:Unc79	UTSW	12	102,957,720 (GRCm39)	missense	probably damaging	1.00
R4576:Unc79	UTSW	12	102,968,062 (GRCm39)	splice site	probably benign
R4645:Unc79	UTSW	12	103,079,081 (GRCm39)	missense	probably benign
R4758:Unc79	UTSW	12	103,128,080 (GRCm39)	nonsense	probably null
R4787:Unc79	UTSW	12	103,013,257 (GRCm39)	missense	probably damaging	1.00
R4852:Unc79	UTSW	12	103,139,725 (GRCm39)	missense	probably damaging	0.98
R4883:Unc79	UTSW	12	103,060,592 (GRCm39)	missense	probably damaging	0.99
R4898:Unc79	UTSW	12	103,128,079 (GRCm39)	missense	probably damaging	0.99
R4979:Unc79	UTSW	12	103,078,691 (GRCm39)	missense	probably benign
R5044:Unc79	UTSW	12	103,078,962 (GRCm39)	missense	probably benign	0.32
R5053:Unc79	UTSW	12	103,071,007 (GRCm39)	missense	probably damaging	1.00
R5061:Unc79	UTSW	12	103,134,700 (GRCm39)	missense	possibly damaging	0.94
R5075:Unc79	UTSW	12	103,041,213 (GRCm39)	missense	possibly damaging	0.63
R5101:Unc79	UTSW	12	103,078,769 (GRCm39)	missense	probably damaging	1.00
R5236:Unc79	UTSW	12	103,060,654 (GRCm39)	critical splice donor site	probably null
R5240:Unc79	UTSW	12	103,037,010 (GRCm39)	missense	probably damaging	0.99
R5383:Unc79	UTSW	12	103,070,886 (GRCm39)	missense	possibly damaging	0.53
R5461:Unc79	UTSW	12	103,078,397 (GRCm39)	missense	probably damaging	1.00
R5535:Unc79	UTSW	12	103,135,962 (GRCm39)	missense	possibly damaging	0.84
R5609:Unc79	UTSW	12	103,094,527 (GRCm39)	missense	probably benign
R5639:Unc79	UTSW	12	103,137,831 (GRCm39)	missense	probably damaging	1.00
R5704:Unc79	UTSW	12	102,968,202 (GRCm39)	missense	probably damaging	1.00
R5923:Unc79	UTSW	12	103,078,727 (GRCm39)	missense	probably damaging	1.00
R5925:Unc79	UTSW	12	103,091,989 (GRCm39)	splice site	probably null
R5975:Unc79	UTSW	12	103,091,885 (GRCm39)	missense	possibly damaging	0.53
R6047:Unc79	UTSW	12	103,027,717 (GRCm39)	missense	probably damaging	1.00
R6156:Unc79	UTSW	12	103,027,717 (GRCm39)	missense	probably damaging	1.00
R6175:Unc79	UTSW	12	103,149,708 (GRCm39)	missense	probably damaging	0.98
R6292:Unc79	UTSW	12	103,108,991 (GRCm39)	missense	possibly damaging	0.88
R6313:Unc79	UTSW	12	103,078,878 (GRCm39)	missense	probably damaging	1.00
R6391:Unc79	UTSW	12	102,987,269 (GRCm39)	missense	probably damaging	1.00
R6405:Unc79	UTSW	12	103,134,595 (GRCm39)	missense	probably damaging	0.97
R6416:Unc79	UTSW	12	103,097,905 (GRCm39)	missense	possibly damaging	0.86
R6467:Unc79	UTSW	12	103,139,771 (GRCm39)	missense	probably damaging	1.00
R6573:Unc79	UTSW	12	103,027,647 (GRCm39)	missense	probably damaging	1.00
R6614:Unc79	UTSW	12	102,957,689 (GRCm39)	missense	probably damaging	1.00
R6654:Unc79	UTSW	12	103,045,308 (GRCm39)	missense	probably damaging	1.00
R6654:Unc79	UTSW	12	103,045,307 (GRCm39)	missense	probably damaging	0.99
R6700:Unc79	UTSW	12	103,091,962 (GRCm39)	missense	possibly damaging	0.92
R6724:Unc79	UTSW	12	103,071,120 (GRCm39)	missense	probably damaging	1.00
R6819:Unc79	UTSW	12	103,108,267 (GRCm39)	missense	probably benign	0.12
R6869:Unc79	UTSW	12	103,079,331 (GRCm39)	missense	probably benign	0.33
R6879:Unc79	UTSW	12	103,115,046 (GRCm39)	splice site	probably null
R6942:Unc79	UTSW	12	103,088,704 (GRCm39)	critical splice donor site	probably null
R6961:Unc79	UTSW	12	103,079,174 (GRCm39)	missense	probably damaging	1.00
R6973:Unc79	UTSW	12	102,964,699 (GRCm39)	missense	possibly damaging	0.86
R6980:Unc79	UTSW	12	103,025,759 (GRCm39)	missense	probably damaging	1.00
R7124:Unc79	UTSW	12	103,027,652 (GRCm39)	missense	probably damaging	0.99
R7144:Unc79	UTSW	12	103,108,885 (GRCm39)	missense	probably benign	0.06
R7197:Unc79	UTSW	12	103,078,765 (GRCm39)	missense	probably benign
R7209:Unc79	UTSW	12	103,091,883 (GRCm39)	missense	probably benign
R7232:Unc79	UTSW	12	103,100,734 (GRCm39)	missense	possibly damaging	0.49
R7304:Unc79	UTSW	12	103,029,449 (GRCm39)	missense	probably damaging	1.00
R7354:Unc79	UTSW	12	103,108,961 (GRCm39)	missense	possibly damaging	0.79
R7384:Unc79	UTSW	12	103,137,837 (GRCm39)	missense	probably benign	0.11
R7400:Unc79	UTSW	12	103,070,889 (GRCm39)	missense	probably damaging	1.00
R7417:Unc79	UTSW	12	103,055,017 (GRCm39)	missense	possibly damaging	0.85
R7470:Unc79	UTSW	12	103,061,235 (GRCm39)	missense	probably damaging	1.00
R7842:Unc79	UTSW	12	103,058,313 (GRCm39)	missense	probably damaging	1.00
R8037:Unc79	UTSW	12	103,016,178 (GRCm39)	missense	probably damaging	1.00
R8041:Unc79	UTSW	12	103,054,726 (GRCm39)	missense	probably benign	0.06
R8146:Unc79	UTSW	12	103,036,416 (GRCm39)	missense	probably damaging	0.98
R8276:Unc79	UTSW	12	102,968,122 (GRCm39)	missense	possibly damaging	0.94
R8427:Unc79	UTSW	12	103,045,297 (GRCm39)	missense	probably benign	0.24
R8501:Unc79	UTSW	12	103,058,897 (GRCm39)	missense	probably damaging	1.00
R8510:Unc79	UTSW	12	103,070,898 (GRCm39)	missense	probably damaging	1.00
R8531:Unc79	UTSW	12	103,013,922 (GRCm39)	missense	probably damaging	1.00
R8531:Unc79	UTSW	12	103,049,855 (GRCm39)	missense	probably benign	0.13
R8795:Unc79	UTSW	12	103,074,513 (GRCm39)	missense	probably damaging	1.00
R9017:Unc79	UTSW	12	103,074,874 (GRCm39)	critical splice acceptor site	probably null
R9121:Unc79	UTSW	12	102,968,095 (GRCm39)	missense	probably damaging	1.00
R9196:Unc79	UTSW	12	103,078,613 (GRCm39)	missense	probably benign
R9443:Unc79	UTSW	12	103,037,035 (GRCm39)	missense	probably damaging	1.00
R9548:Unc79	UTSW	12	102,977,495 (GRCm39)	missense	probably damaging	1.00
R9600:Unc79	UTSW	12	103,135,972 (GRCm39)	missense	probably benign	0.07
R9767:Unc79	UTSW	12	103,079,234 (GRCm39)	missense	probably benign
R9787:Unc79	UTSW	12	103,112,620 (GRCm39)	missense	probably benign	0.00
RF010:Unc79	UTSW	12	103,079,046 (GRCm39)	missense	probably benign	0.17
X0017:Unc79	UTSW	12	103,074,520 (GRCm39)	missense	probably damaging	0.99
X0028:Unc79	UTSW	12	102,957,662 (GRCm39)	missense	probably damaging	1.00
Z1088:Unc79	UTSW	12	102,987,271 (GRCm39)	missense	probably damaging	1.00
Z1176:Unc79	UTSW	12	103,108,312 (GRCm39)	missense	probably benign	0.03
Z1176:Unc79	UTSW	12	103,054,937 (GRCm39)	missense	probably damaging	1.00
Z1177:Unc79	UTSW	12	103,131,948 (GRCm39)	missense	probably benign

Posted On

2016-08-02