Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03178:Pate12'

412066

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Pate12

Ensembl Gene

ENSMUSG00000023093

Gene Name

prostate and testis expressed 12

Synonyms

Gm7257

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.053) question?

Stock #

IGL03178

Quality Score

Status

Chromosome

Chromosomal Location

36343180-36346234 bp(+) (GRCm39)

Type of Mutation

missense

DNA Base Change (assembly)

T to G at 36344132 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Serine to Arginine at position 38 (S38R)

Ref Sequence

ENSEMBL: ENSMUSP00000048154 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000041537]

AlphaFold

D3YX25

Predicted Effect

probably benign
Transcript: ENSMUST00000041537
AA Change: S38R

PolyPhen 2 Score 0.000 (Sensitivity: 1.00; Specificity: 0.00)

SMART Domains

Protein: ENSMUSP00000048154
Gene: ENSMUSG00000023093
AA Change: S38R

Domain	Start	End	E-Value	Type
signal peptide	1	21	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 47 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Add1	A	G	5: 34,771,589 (GRCm39)		probably null	Het
Afg2a	T	C	3: 37,632,932 (GRCm39)	L846P	probably damaging	Het
Alpk1	A	T	3: 127,473,870 (GRCm39)	L711*	probably null	Het
Arfgef3	A	T	10: 18,488,973 (GRCm39)	W1291R	probably damaging	Het
Arhgef10l	A	G	4: 140,271,739 (GRCm39)	V545A	possibly damaging	Het
Best3	A	G	10: 116,824,684 (GRCm39)	Y50C	probably damaging	Het
C1qtnf2	C	A	11: 43,381,816 (GRCm39)	D179E	probably damaging	Het
Cdc40	A	T	10: 40,723,985 (GRCm39)	S268T	probably benign	Het
Ces1a	C	T	8: 93,747,517 (GRCm39)	G505R	probably damaging	Het
Cpd	A	T	11: 76,696,877 (GRCm39)	N683K	probably benign	Het
D430041D05Rik	A	T	2: 104,051,556 (GRCm39)	I767N	probably damaging	Het
Diras1	G	T	10: 80,858,211 (GRCm39)	F13L	possibly damaging	Het
Dnah7c	A	G	1: 46,506,525 (GRCm39)	N201D	probably benign	Het
Dpy19l3	A	T	7: 35,429,154 (GRCm39)	Y9*	probably null	Het
Ect2	T	A	3: 27,203,009 (GRCm39)	I79L	probably benign	Het
Eif2b4	A	T	5: 31,344,997 (GRCm39)	I550N	probably damaging	Het
Enpp2	T	A	15: 54,729,402 (GRCm39)	M476L	probably benign	Het
Gm20425	A	G	9: 103,087,751 (GRCm39)	Y654H	probably damaging	Het
Gm5884	T	C	6: 128,622,690 (GRCm39)		noncoding transcript	Het
Gtf3c6	A	T	10: 40,125,718 (GRCm39)	D166E	probably benign	Het
Gucy2c	A	T	6: 136,706,237 (GRCm39)		probably benign	Het
Inpp5b	A	G	4: 124,679,047 (GRCm39)	T485A	probably benign	Het
Insrr	A	G	3: 87,709,848 (GRCm39)		probably null	Het
Lig3	T	C	11: 82,680,548 (GRCm39)		probably benign	Het
Lmo7	T	A	14: 102,166,696 (GRCm39)	Y1047*	probably null	Het
Map4k4	A	G	1: 40,025,853 (GRCm39)	E281G	possibly damaging	Het
Mmel1	A	G	4: 154,975,311 (GRCm39)	T431A	possibly damaging	Het
Myh10	T	C	11: 68,590,239 (GRCm39)	V58A	probably benign	Het
Myo1e	A	T	9: 70,194,231 (GRCm39)	H14L	possibly damaging	Het
Myo1g	C	T	11: 6,462,181 (GRCm39)	V594M	probably damaging	Het
Nr4a2	G	A	2: 57,000,778 (GRCm39)	R226C	probably damaging	Het
Obox3	A	G	7: 15,361,202 (GRCm39)	L21P	probably benign	Het
Or2y13	A	G	11: 49,414,817 (GRCm39)	D89G	possibly damaging	Het
Phlpp1	T	A	1: 106,320,118 (GRCm39)	I1371N	probably damaging	Het
Pramel29	A	G	4: 143,934,821 (GRCm39)		probably null	Het
Proser3	G	A	7: 30,243,034 (GRCm39)	A181V	probably damaging	Het
Pudp	A	T	18: 50,701,472 (GRCm39)	L87Q	probably benign	Het
Siglecf	T	C	7: 43,008,163 (GRCm39)	S559P	probably damaging	Het
Slc22a16	A	G	10: 40,449,756 (GRCm39)	H85R	probably benign	Het
Spata32	T	C	11: 103,101,588 (GRCm39)	D15G	probably benign	Het
Szt2	G	A	4: 118,239,886 (GRCm39)	A1899V	unknown	Het
Tomm40	C	T	7: 19,435,759 (GRCm39)	V324M	probably damaging	Het
Trgv7	C	A	13: 19,362,211 (GRCm39)		probably benign	Het
Ttll4	C	T	1: 74,719,567 (GRCm39)	P25S	probably damaging	Het
Vps13b	G	T	15: 35,869,446 (GRCm39)	C2650F	probably damaging	Het
Wdr83os	T	C	8: 85,807,870 (GRCm39)	L40P	probably damaging	Het
Zfp977	T	C	7: 42,232,072 (GRCm39)	R64G	probably damaging	Het

Other mutations in Pate12

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00329:Pate12	APN	9	36,344,198 (GRCm39)	splice site	probably benign
IGL01799:Pate12	APN	9	36,344,179 (GRCm39)	missense	possibly damaging	0.59
IGL03018:Pate12	APN	9	36,344,723 (GRCm39)	missense	possibly damaging	0.89
IGL03284:Pate12	APN	9	36,344,759 (GRCm39)	missense	probably damaging	1.00
R1157:Pate12	UTSW	9	36,344,143 (GRCm39)	missense	probably benign	0.01
R2032:Pate12	UTSW	9	36,344,195 (GRCm39)	critical splice donor site	probably null
R4879:Pate12	UTSW	9	36,344,089 (GRCm39)	missense	probably damaging	1.00
R4954:Pate12	UTSW	9	36,344,156 (GRCm39)	missense	probably benign	0.28
R5019:Pate12	UTSW	9	36,343,198 (GRCm39)	missense	probably benign	0.05

Posted On

2016-08-02