Incidental Mutation 'IGL03182:Slit2'
ID 412296
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Slit2
Ensembl Gene ENSMUSG00000031558
Gene Name slit guidance ligand 2
Synonyms E030015M03Rik, Drad-1, b2b1200.1Clo, Slil3, E130320P19Rik
Accession Numbers
Essential gene? Essential (E-score: 1.000) question?
Stock # IGL03182
Quality Score
Status
Chromosome 5
Chromosomal Location 48140480-48465075 bp(+) (GRCm39)
Type of Mutation missense
DNA Base Change (assembly) A to G at 48377395 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change Isoleucine to Valine at position 475 (I475V)
Ref Sequence ENSEMBL: ENSMUSP00000133912 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000033967] [ENSMUST00000170109] [ENSMUST00000173107] [ENSMUST00000174313] [ENSMUST00000174421]
AlphaFold Q9R1B9
Predicted Effect possibly damaging
Transcript: ENSMUST00000033967
AA Change: I471V

PolyPhen 2 Score 0.580 (Sensitivity: 0.88; Specificity: 0.91)
SMART Domains Protein: ENSMUSP00000033967
Gene: ENSMUSG00000031558
AA Change: I471V

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
LRRNT 27 59 6.53e-9 SMART
LRR 53 77 1.41e2 SMART
LRR_TYP 78 101 1.79e-2 SMART
LRR 102 125 2.45e0 SMART
LRR 126 149 9.96e-1 SMART
LRR 154 173 1.29e2 SMART
LRR_TYP 174 197 2.05e-2 SMART
LRRCT 209 258 3.42e-9 SMART
LRRNT 272 304 4.55e-8 SMART
LRR 298 322 3e1 SMART
LRR_TYP 323 346 1.95e-3 SMART
LRR_TYP 347 370 2.24e-3 SMART
LRR 371 394 1.31e0 SMART
LRR 395 418 2.49e-1 SMART
LRRCT 430 479 1.88e-6 SMART
LRRNT 497 529 1.45e-6 SMART
LRR_TYP 549 572 1.38e-3 SMART
LRR 597 620 9.96e-1 SMART
LRR_TYP 621 644 2.71e-2 SMART
LRRCT 656 705 3.56e-7 SMART
LRRNT 718 750 3.69e-8 SMART
LRR 768 791 7.36e0 SMART
LRR_TYP 792 815 5.59e-4 SMART
LRR_TYP 816 839 7.9e-4 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000083669
Predicted Effect possibly damaging
Transcript: ENSMUST00000170109
AA Change: I475V

PolyPhen 2 Score 0.766 (Sensitivity: 0.85; Specificity: 0.92)
SMART Domains Protein: ENSMUSP00000127615
Gene: ENSMUSG00000031558
AA Change: I475V

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
LRRNT 27 59 6.53e-9 SMART
LRR 53 77 1.41e2 SMART
LRR_TYP 78 101 1.79e-2 SMART
LRR 102 125 2.45e0 SMART
LRR 126 149 9.96e-1 SMART
LRR 154 173 1.29e2 SMART
LRR_TYP 174 197 2.05e-2 SMART
LRRCT 209 258 3.42e-9 SMART
LRRNT 272 304 4.55e-8 SMART
LRR 298 322 3e1 SMART
LRR_TYP 323 346 1.95e-3 SMART
LRR_TYP 347 370 2.24e-3 SMART
LRR 371 394 1.31e0 SMART
LRR 395 418 2.49e-1 SMART
LRRCT 430 479 1.88e-6 SMART
LRRNT 497 529 1.45e-6 SMART
LRR_TYP 549 572 1.38e-3 SMART
LRR 597 620 9.96e-1 SMART
LRR_TYP 621 644 2.71e-2 SMART
LRRCT 656 705 3.56e-7 SMART
LRRNT 718 750 3.69e-8 SMART
LRR 768 791 7.36e0 SMART
LRR_TYP 792 815 5.59e-4 SMART
LRR_TYP 816 839 7.9e-4 SMART
LRRCT 851 900 3.9e-13 SMART
EGF 913 947 3.73e-5 SMART
EGF 952 988 4.35e-6 SMART
EGF_CA 990 1026 2.21e-7 SMART
FOLN 993 1015 5.84e1 SMART
EGF 1031 1066 1.07e-5 SMART
EGF_CA 1068 1104 3.97e-9 SMART
FOLN 1116 1138 2.22e0 SMART
EGF 1116 1149 1.62e-5 SMART
LamG 1172 1308 4.82e-39 SMART
EGF 1327 1360 3.68e-4 SMART
EGF 1366 1399 3.88e-3 SMART
FOLN 1407 1429 3.34e0 SMART
EGF 1407 1440 4.46e-3 SMART
CT 1451 1520 4.23e-4 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000172824
Predicted Effect probably benign
Transcript: ENSMUST00000173107
AA Change: I471V

PolyPhen 2 Score 0.102 (Sensitivity: 0.93; Specificity: 0.86)
SMART Domains Protein: ENSMUSP00000133840
Gene: ENSMUSG00000031558
AA Change: I471V

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
LRRNT 27 59 6.53e-9 SMART
LRR 53 77 1.41e2 SMART
LRR_TYP 78 101 1.79e-2 SMART
LRR 102 125 2.45e0 SMART
LRR 126 149 9.96e-1 SMART
LRR 154 173 1.29e2 SMART
LRR_TYP 174 197 2.05e-2 SMART
LRRCT 209 258 3.42e-9 SMART
LRRNT 272 304 4.55e-8 SMART
LRR 298 322 3e1 SMART
LRR_TYP 323 346 1.95e-3 SMART
LRR_TYP 347 370 2.24e-3 SMART
LRR 371 394 1.31e0 SMART
LRR 395 418 2.49e-1 SMART
LRRCT 430 479 1.88e-6 SMART
LRRNT 505 537 1.45e-6 SMART
LRR_TYP 557 580 1.38e-3 SMART
LRR 605 628 9.96e-1 SMART
LRR_TYP 629 652 2.71e-2 SMART
LRRCT 664 713 3.56e-7 SMART
LRRNT 726 758 3.69e-8 SMART
LRR 776 799 7.36e0 SMART
LRR_TYP 800 823 5.59e-4 SMART
LRR_TYP 824 847 7.9e-4 SMART
LRRCT 859 908 3.9e-13 SMART
EGF 921 955 3.73e-5 SMART
EGF 960 996 4.35e-6 SMART
EGF_CA 998 1034 2.21e-7 SMART
FOLN 1001 1023 5.84e1 SMART
EGF 1039 1074 1.07e-5 SMART
EGF_CA 1076 1112 3.97e-9 SMART
FOLN 1124 1146 2.22e0 SMART
EGF 1124 1157 1.62e-5 SMART
LamG 1180 1316 4.82e-39 SMART
EGF 1335 1368 3.68e-4 SMART
EGF 1374 1407 3.88e-3 SMART
FOLN 1415 1437 3.34e0 SMART
EGF 1415 1448 4.46e-3 SMART
CT 1459 1528 4.23e-4 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000173303
Predicted Effect possibly damaging
Transcript: ENSMUST00000174313
AA Change: I475V

PolyPhen 2 Score 0.766 (Sensitivity: 0.85; Specificity: 0.92)
SMART Domains Protein: ENSMUSP00000133912
Gene: ENSMUSG00000031558
AA Change: I475V

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
LRRNT 27 59 6.53e-9 SMART
LRR 53 77 1.41e2 SMART
LRR_TYP 78 101 1.79e-2 SMART
LRR 102 125 2.45e0 SMART
LRR 126 149 9.96e-1 SMART
LRR 154 173 1.29e2 SMART
LRR_TYP 174 197 2.05e-2 SMART
LRRCT 209 258 3.42e-9 SMART
LRRNT 276 308 4.55e-8 SMART
LRR 302 326 3e1 SMART
LRR_TYP 327 350 1.95e-3 SMART
LRR_TYP 351 374 2.24e-3 SMART
LRR 375 398 1.31e0 SMART
LRR 399 422 2.49e-1 SMART
LRRCT 434 483 1.88e-6 SMART
LRRNT 501 533 1.45e-6 SMART
LRR_TYP 553 576 1.38e-3 SMART
LRR 601 624 9.96e-1 SMART
LRR_TYP 625 648 2.71e-2 SMART
LRRCT 660 709 3.56e-7 SMART
LRRNT 722 754 3.69e-8 SMART
LRR 772 795 7.36e0 SMART
LRR_TYP 796 819 5.59e-4 SMART
LRR_TYP 820 843 7.9e-4 SMART
LRRCT 855 904 3.9e-13 SMART
EGF 917 951 3.73e-5 SMART
EGF 956 992 4.35e-6 SMART
EGF_CA 994 1030 2.21e-7 SMART
FOLN 997 1019 5.84e1 SMART
EGF 1035 1070 1.07e-5 SMART
EGF_CA 1072 1108 3.97e-9 SMART
FOLN 1120 1142 2.22e0 SMART
EGF 1120 1153 1.62e-5 SMART
LamG 1176 1312 4.82e-39 SMART
EGF 1331 1364 3.68e-4 SMART
EGF 1370 1403 3.88e-3 SMART
FOLN 1411 1433 3.34e0 SMART
EGF 1411 1444 4.46e-3 SMART
CT 1455 1524 4.23e-4 SMART
Predicted Effect probably benign
Transcript: ENSMUST00000174421
AA Change: I475V

PolyPhen 2 Score 0.020 (Sensitivity: 0.95; Specificity: 0.80)
SMART Domains Protein: ENSMUSP00000134263
Gene: ENSMUSG00000031558
AA Change: I475V

DomainStartEndE-ValueType
signal peptide 1 18 N/A INTRINSIC
LRRNT 27 59 6.53e-9 SMART
LRR 53 77 1.41e2 SMART
LRR_TYP 78 101 1.79e-2 SMART
LRR 102 125 2.45e0 SMART
LRR 126 149 9.96e-1 SMART
LRR 154 173 1.29e2 SMART
LRR_TYP 174 197 2.05e-2 SMART
LRRCT 209 258 3.42e-9 SMART
LRRNT 276 308 4.55e-8 SMART
LRR 302 326 3e1 SMART
LRR_TYP 327 350 1.95e-3 SMART
LRR_TYP 351 374 2.24e-3 SMART
LRR 375 398 1.31e0 SMART
LRR 399 422 2.49e-1 SMART
LRRCT 434 483 1.88e-6 SMART
LRRNT 509 541 1.45e-6 SMART
LRR_TYP 561 584 1.38e-3 SMART
LRR 609 632 9.96e-1 SMART
LRR_TYP 633 656 2.71e-2 SMART
LRRCT 668 717 3.56e-7 SMART
LRRNT 730 762 3.69e-8 SMART
LRR 780 803 7.36e0 SMART
LRR_TYP 804 827 5.59e-4 SMART
LRR_TYP 828 851 7.9e-4 SMART
LRRCT 863 912 3.9e-13 SMART
EGF 925 959 3.73e-5 SMART
EGF 964 1000 4.35e-6 SMART
EGF_CA 1002 1047 4.74e-7 SMART
FOLN 1005 1027 5.84e1 SMART
EGF 1052 1087 1.07e-5 SMART
EGF_CA 1089 1125 3.97e-9 SMART
FOLN 1137 1159 2.22e0 SMART
EGF 1137 1170 1.62e-5 SMART
LamG 1193 1329 4.82e-39 SMART
EGF 1348 1381 3.68e-4 SMART
EGF 1387 1420 3.88e-3 SMART
FOLN 1428 1450 3.34e0 SMART
EGF 1428 1461 4.46e-3 SMART
CT 1472 1541 4.23e-4 SMART
Predicted Effect noncoding transcript
Transcript: ENSMUST00000174487
Coding Region Coverage
Validation Efficiency
MGI Phenotype FUNCTION: The protein encoded by this gene is a member of the Slit family of secreted glycoproteins, which function as ligands for the Robo family of immunoglobulin receptors. Slit proteins play highly conserved roles in axon guidance and neuronal migration and may also have functions during other cell migration processes including leukocyte migration. In mammals, members of the slit family are characterized by an N-terminal signal peptide, four leucine-rich repeats, nine epidermal growth factor repeats, and a C-terminal cysteine knot. Mice deficient for this gene exhibit abnormal axonal projections in the embryonic forebrain and develop supernumerary uretic buds that maintain improper connections to the nephric duct. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015]
PHENOTYPE: Homozygous mutants display perinatal lethality, abnormal ureteric bud development, multiple fused kidneys, multiple ureters, and hydroureter. [provided by MGI curators]
Allele List at MGI

All alleles(4) : Targeted(4)
Other mutations in this stock
Total: 42 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Agbl3 A T 6: 34,780,435 (GRCm39) K469N probably damaging Het
Aldh2 A G 5: 121,718,787 (GRCm39) probably benign Het
Ankfy1 T C 11: 72,619,580 (GRCm39) probably benign Het
Ankhd1 C T 18: 36,711,827 (GRCm39) T209I probably benign Het
Aox3 G A 1: 58,205,046 (GRCm39) V754I probably benign Het
Arfgef3 C T 10: 18,476,292 (GRCm39) R1509H probably damaging Het
Ccdc157 A G 11: 4,101,832 (GRCm39) S30P probably damaging Het
Cept1 T A 3: 106,411,866 (GRCm39) E369D probably damaging Het
Clcnka T C 4: 141,121,798 (GRCm39) Y236C probably damaging Het
Ddx42 A T 11: 106,138,353 (GRCm39) L717F probably benign Het
Dnah11 A T 12: 117,994,026 (GRCm39) I2340N probably damaging Het
Dsel T C 1: 111,787,868 (GRCm39) E889G probably damaging Het
Fasn T C 11: 120,703,552 (GRCm39) Y1560C probably damaging Het
Fermt2 A T 14: 45,699,225 (GRCm39) M623K possibly damaging Het
Gm21970 T A 16: 91,190,726 (GRCm39) S110T possibly damaging Het
Gm826 T A 2: 160,169,035 (GRCm39) R91S unknown Het
Lrrn3 A G 12: 41,504,020 (GRCm39) L99S probably damaging Het
Megf8 T A 7: 25,046,773 (GRCm39) M1552K possibly damaging Het
Mgll G T 6: 88,800,173 (GRCm39) V191F probably damaging Het
Nkapd1 T C 9: 50,523,698 (GRCm39) N50S possibly damaging Het
Nol8 C A 13: 49,817,557 (GRCm39) H778N probably damaging Het
Or1e26 T A 11: 73,480,268 (GRCm39) T99S probably benign Het
Or5b116 A C 19: 13,422,807 (GRCm39) T144P possibly damaging Het
Or8g30 A T 9: 39,230,277 (GRCm39) M211K probably benign Het
Or8k40 A T 2: 86,584,366 (GRCm39) S239T probably damaging Het
Pfkfb3 A T 2: 11,506,474 (GRCm39) I13N probably damaging Het
Pim1 T A 17: 29,710,740 (GRCm39) D114E possibly damaging Het
Pkd1 T C 17: 24,792,792 (GRCm39) L1493P probably damaging Het
Plb1 A T 5: 32,502,259 (GRCm39) probably benign Het
Plch1 A T 3: 63,610,015 (GRCm39) Y872* probably null Het
Rictor A G 15: 6,819,079 (GRCm39) D1434G probably benign Het
Rptor G A 11: 119,615,971 (GRCm39) G162R probably damaging Het
Serping1 T C 2: 84,596,162 (GRCm39) D424G probably damaging Het
Snx31 G T 15: 36,525,833 (GRCm39) Q289K probably benign Het
Tbc1d13 G A 2: 30,037,379 (GRCm39) A254T probably damaging Het
Tek T C 4: 94,740,002 (GRCm39) I750T probably damaging Het
Tet2 A T 3: 133,177,159 (GRCm39) L1296* probably null Het
Tmem145 T A 7: 25,014,304 (GRCm39) F459I probably damaging Het
Uba5 A T 9: 103,931,328 (GRCm39) V247D possibly damaging Het
Vmn1r83 T C 7: 12,055,617 (GRCm39) M147V probably benign Het
Vwde T C 6: 13,187,138 (GRCm39) D783G probably damaging Het
Zfp609 A G 9: 65,608,287 (GRCm39) S1198P probably benign Het
Other mutations in Slit2
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00791:Slit2 APN 5 48,461,374 (GRCm39) missense possibly damaging 0.86
IGL00809:Slit2 APN 5 48,146,493 (GRCm39) missense possibly damaging 0.88
IGL00811:Slit2 APN 5 48,146,493 (GRCm39) missense possibly damaging 0.88
IGL00813:Slit2 APN 5 48,146,493 (GRCm39) missense possibly damaging 0.88
IGL00815:Slit2 APN 5 48,146,493 (GRCm39) missense possibly damaging 0.88
IGL00816:Slit2 APN 5 48,146,493 (GRCm39) missense possibly damaging 0.88
IGL00817:Slit2 APN 5 48,146,493 (GRCm39) missense possibly damaging 0.88
IGL00819:Slit2 APN 5 48,146,493 (GRCm39) missense possibly damaging 0.88
IGL00820:Slit2 APN 5 48,146,493 (GRCm39) missense possibly damaging 0.88
IGL00822:Slit2 APN 5 48,146,493 (GRCm39) missense possibly damaging 0.88
IGL01077:Slit2 APN 5 48,374,785 (GRCm39) splice site probably null
IGL01375:Slit2 APN 5 48,439,056 (GRCm39) splice site probably benign
IGL01481:Slit2 APN 5 48,460,273 (GRCm39) missense probably benign 0.05
IGL01934:Slit2 APN 5 48,395,747 (GRCm39) missense possibly damaging 0.93
IGL01992:Slit2 APN 5 48,395,759 (GRCm39) missense probably benign 0.01
IGL02315:Slit2 APN 5 48,145,213 (GRCm39) missense probably damaging 0.98
IGL02328:Slit2 APN 5 48,387,646 (GRCm39) missense probably damaging 1.00
IGL02366:Slit2 APN 5 48,461,410 (GRCm39) missense possibly damaging 0.53
IGL02526:Slit2 APN 5 48,461,565 (GRCm39) nonsense probably null
IGL02852:Slit2 APN 5 48,402,014 (GRCm39) missense probably damaging 1.00
IGL02887:Slit2 APN 5 48,374,816 (GRCm39) missense probably benign 0.44
IGL03123:Slit2 APN 5 48,368,681 (GRCm39) missense probably damaging 1.00
P0025:Slit2 UTSW 5 48,461,377 (GRCm39) missense probably damaging 0.96
R0032:Slit2 UTSW 5 48,414,198 (GRCm39) missense probably damaging 0.99
R0032:Slit2 UTSW 5 48,414,198 (GRCm39) missense probably damaging 0.99
R0055:Slit2 UTSW 5 48,439,068 (GRCm39) nonsense probably null
R0055:Slit2 UTSW 5 48,439,068 (GRCm39) nonsense probably null
R0267:Slit2 UTSW 5 48,339,673 (GRCm39) splice site probably benign
R0552:Slit2 UTSW 5 48,395,721 (GRCm39) missense probably damaging 1.00
R0610:Slit2 UTSW 5 48,433,016 (GRCm39) missense possibly damaging 0.77
R0883:Slit2 UTSW 5 48,402,915 (GRCm39) splice site probably benign
R1390:Slit2 UTSW 5 48,374,832 (GRCm39) missense probably benign 0.06
R1442:Slit2 UTSW 5 48,395,725 (GRCm39) missense probably damaging 0.96
R1453:Slit2 UTSW 5 48,414,393 (GRCm39) missense possibly damaging 0.88
R1508:Slit2 UTSW 5 48,349,591 (GRCm39) missense probably damaging 0.98
R1639:Slit2 UTSW 5 48,416,996 (GRCm39) missense probably damaging 1.00
R1705:Slit2 UTSW 5 48,346,814 (GRCm39) missense probably damaging 0.99
R1828:Slit2 UTSW 5 48,461,372 (GRCm39) missense probably damaging 1.00
R1897:Slit2 UTSW 5 48,395,765 (GRCm39) missense probably damaging 1.00
R1908:Slit2 UTSW 5 48,439,330 (GRCm39) missense probably damaging 1.00
R1919:Slit2 UTSW 5 48,348,358 (GRCm39) unclassified probably benign
R1982:Slit2 UTSW 5 48,407,178 (GRCm39) missense probably damaging 1.00
R2013:Slit2 UTSW 5 48,459,832 (GRCm39) missense probably damaging 1.00
R2136:Slit2 UTSW 5 48,461,567 (GRCm39) missense probably benign 0.03
R2655:Slit2 UTSW 5 48,346,917 (GRCm39) missense possibly damaging 0.88
R3402:Slit2 UTSW 5 48,440,763 (GRCm39) missense probably damaging 0.98
R3724:Slit2 UTSW 5 48,414,225 (GRCm39) critical splice donor site probably null
R4176:Slit2 UTSW 5 48,394,586 (GRCm39) splice site probably null
R4306:Slit2 UTSW 5 48,460,125 (GRCm39) missense possibly damaging 0.83
R4397:Slit2 UTSW 5 48,377,423 (GRCm39) critical splice donor site probably null
R4525:Slit2 UTSW 5 48,407,215 (GRCm39) missense probably damaging 1.00
R4688:Slit2 UTSW 5 48,414,345 (GRCm39) splice site probably null
R5026:Slit2 UTSW 5 48,414,147 (GRCm39) missense probably damaging 0.99
R5138:Slit2 UTSW 5 48,439,309 (GRCm39) missense probably damaging 1.00
R5465:Slit2 UTSW 5 48,407,254 (GRCm39) missense probably damaging 1.00
R5471:Slit2 UTSW 5 48,346,897 (GRCm39) missense probably damaging 1.00
R5699:Slit2 UTSW 5 48,378,333 (GRCm39) critical splice donor site probably null
R5735:Slit2 UTSW 5 48,416,958 (GRCm39) missense probably damaging 1.00
R5834:Slit2 UTSW 5 48,416,989 (GRCm39) missense probably damaging 1.00
R5967:Slit2 UTSW 5 48,142,506 (GRCm39) missense probably damaging 0.99
R6150:Slit2 UTSW 5 48,461,516 (GRCm39) missense probably damaging 1.00
R6219:Slit2 UTSW 5 48,459,770 (GRCm39) missense possibly damaging 0.53
R6344:Slit2 UTSW 5 48,377,023 (GRCm39) missense probably benign 0.07
R6408:Slit2 UTSW 5 48,142,328 (GRCm39) unclassified probably benign
R6479:Slit2 UTSW 5 48,389,331 (GRCm39) missense probably damaging 1.00
R6526:Slit2 UTSW 5 48,461,509 (GRCm39) missense probably damaging 0.99
R6959:Slit2 UTSW 5 48,395,727 (GRCm39) missense possibly damaging 0.83
R7139:Slit2 UTSW 5 48,402,025 (GRCm39) missense probably benign 0.19
R7201:Slit2 UTSW 5 48,394,627 (GRCm39) missense probably null 0.85
R7472:Slit2 UTSW 5 48,414,180 (GRCm39) missense probably damaging 0.97
R7491:Slit2 UTSW 5 48,377,336 (GRCm39) missense probably benign 0.18
R7566:Slit2 UTSW 5 48,407,239 (GRCm39) missense probably damaging 0.99
R7622:Slit2 UTSW 5 48,142,547 (GRCm39) missense probably damaging 0.98
R7831:Slit2 UTSW 5 48,402,025 (GRCm39) missense probably benign 0.19
R7870:Slit2 UTSW 5 48,459,649 (GRCm39) missense probably damaging 0.99
R7899:Slit2 UTSW 5 48,404,527 (GRCm39) missense possibly damaging 0.89
R7969:Slit2 UTSW 5 48,461,378 (GRCm39) missense possibly damaging 0.47
R7984:Slit2 UTSW 5 48,333,465 (GRCm39) intron probably benign
R8021:Slit2 UTSW 5 48,459,834 (GRCm39) nonsense probably null
R8253:Slit2 UTSW 5 48,433,013 (GRCm39) missense probably benign 0.00
R8321:Slit2 UTSW 5 48,387,609 (GRCm39) missense probably damaging 1.00
R8426:Slit2 UTSW 5 48,382,105 (GRCm39) missense probably benign 0.00
R8513:Slit2 UTSW 5 48,382,050 (GRCm39) nonsense probably null
R8756:Slit2 UTSW 5 48,459,829 (GRCm39) nonsense probably null
R8796:Slit2 UTSW 5 48,460,190 (GRCm39) missense probably benign 0.01
R8799:Slit2 UTSW 5 48,461,524 (GRCm39) missense possibly damaging 0.73
R8947:Slit2 UTSW 5 48,407,140 (GRCm39) missense probably damaging 1.00
R9005:Slit2 UTSW 5 48,459,860 (GRCm39) missense possibly damaging 0.73
R9173:Slit2 UTSW 5 48,377,285 (GRCm39) missense probably damaging 0.98
R9310:Slit2 UTSW 5 48,349,568 (GRCm39) missense possibly damaging 0.59
R9365:Slit2 UTSW 5 48,461,534 (GRCm39) missense probably benign 0.04
Z1088:Slit2 UTSW 5 48,459,695 (GRCm39) missense probably damaging 1.00
Posted On 2016-08-02