Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03202:Vmn2r108'

413007

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Vmn2r108

Ensembl Gene

ENSMUSG00000091805

Gene Name

vomeronasal 2, receptor 108

Synonyms

EG627805

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.073) question?

Stock #

IGL03202

Quality Score

Status

Chromosome

Chromosomal Location

20682635-20701498 bp(-) (GRCm39)

Type of Mutation

nonsense

DNA Base Change (assembly)

A to T at 20691319 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Tyrosine to Stop codon at position 401 (Y401*)

Ref Sequence

ENSEMBL: ENSMUSP00000130373 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000167314]

AlphaFold

E9PYS0

Predicted Effect

probably null
Transcript: ENSMUST00000167314
AA Change: Y401*

SMART Domains

Protein: ENSMUSP00000130373
Gene: ENSMUSG00000091805
AA Change: Y401*

Domain	Start	End	E-Value	Type
signal peptide	1	19	N/A	INTRINSIC
Pfam:ANF_receptor	83	467	6e-33	PFAM
Pfam:NCD3G	510	563	9.2e-22	PFAM
Pfam:7tm_3	593	831	2.2e-51	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 35 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
1700113H08Rik	T	C	10: 86,909,911 (GRCm39)	M1T	probably null	Het
Ace	T	A	11: 105,867,788 (GRCm39)	I168N	probably damaging	Het
Actr10	T	G	12: 70,987,605 (GRCm39)	C37W	probably damaging	Het
Atp10b	T	C	11: 43,125,268 (GRCm39)		probably null	Het
Bend5	A	G	4: 111,290,441 (GRCm39)	N146D	possibly damaging	Het
Cacna1b	A	G	2: 24,541,124 (GRCm39)	F1347L	probably damaging	Het
Crybg3	T	A	16: 59,315,072 (GRCm39)	I2910F	probably damaging	Het
Cspg4	T	C	9: 56,805,023 (GRCm39)	S1945P	possibly damaging	Het
Cxcr4	T	G	1: 128,516,641 (GRCm39)	K340T	probably damaging	Het
Dnah6	T	A	6: 73,121,683 (GRCm39)	Y1433F	probably damaging	Het
Eif2ak4	T	C	2: 118,231,101 (GRCm39)	V77A	probably damaging	Het
Fscn3	A	T	6: 28,434,451 (GRCm39)	H342L	probably benign	Het
Gm9843	T	C	16: 76,200,234 (GRCm39)		noncoding transcript	Het
Hdac9	T	C	12: 34,423,950 (GRCm39)	E520G	probably damaging	Het
Itm2b	G	A	14: 73,603,229 (GRCm39)	P120L	probably damaging	Het
Itpa	T	A	2: 130,509,859 (GRCm39)		probably benign	Het
Lce1l	A	T	3: 92,757,631 (GRCm39)	C76S	unknown	Het
Lin54	A	G	5: 100,623,673 (GRCm39)	S55P	possibly damaging	Het
Lrrc37	T	A	11: 103,506,199 (GRCm39)	E1923V	probably benign	Het
Mtfmt	C	A	9: 65,356,008 (GRCm39)	P303Q	probably damaging	Het
Nae1	A	T	8: 105,244,811 (GRCm39)		probably benign	Het
Ncapd3	T	A	9: 26,983,011 (GRCm39)		probably benign	Het
Or13a19	A	G	7: 139,903,019 (GRCm39)	M136V	possibly damaging	Het
Or1e22	G	A	11: 73,377,351 (GRCm39)	Q100*	probably null	Het
Pcnx2	A	C	8: 126,498,783 (GRCm39)	I1572S	probably damaging	Het
Piezo2	A	T	18: 63,144,669 (GRCm39)	Y2809N	probably damaging	Het
Pygl	G	T	12: 70,246,420 (GRCm39)	Q376K	probably benign	Het
Resf1	G	A	6: 149,227,937 (GRCm39)	V328I	probably benign	Het
Rrp12	T	C	19: 41,857,205 (GRCm39)		probably null	Het
Sephs1	A	T	2: 4,894,074 (GRCm39)	I92F	possibly damaging	Het
Taar4	T	C	10: 23,836,692 (GRCm39)	F101L	probably damaging	Het
Tenm2	A	G	11: 35,915,375 (GRCm39)	I2053T	probably damaging	Het
Tgfbr3	T	G	5: 107,257,630 (GRCm39)		probably benign	Het
Vmn2r87	A	G	10: 130,333,091 (GRCm39)	M53T	probably benign	Het
Zfp941	A	G	7: 140,392,966 (GRCm39)	V131A	probably benign	Het

Other mutations in Vmn2r108

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00903:Vmn2r108	APN	17	20,682,774 (GRCm39)	missense	probably damaging	0.98
IGL01143:Vmn2r108	APN	17	20,682,727 (GRCm39)	missense	possibly damaging	0.82
IGL01311:Vmn2r108	APN	17	20,682,939 (GRCm39)	nonsense	probably null
IGL01411:Vmn2r108	APN	17	20,691,282 (GRCm39)	missense	probably benign	0.01
IGL01414:Vmn2r108	APN	17	20,691,942 (GRCm39)	missense	probably benign	0.00
IGL01536:Vmn2r108	APN	17	20,683,543 (GRCm39)	missense	probably damaging	1.00
IGL01748:Vmn2r108	APN	17	20,683,476 (GRCm39)	missense	probably benign	0.03
IGL01769:Vmn2r108	APN	17	20,691,280 (GRCm39)	missense	probably benign	0.02
IGL02022:Vmn2r108	APN	17	20,691,987 (GRCm39)	missense	possibly damaging	0.77
IGL02041:Vmn2r108	APN	17	20,683,398 (GRCm39)	missense	probably damaging	1.00
IGL02049:Vmn2r108	APN	17	20,691,608 (GRCm39)	missense	probably benign	0.00
IGL02344:Vmn2r108	APN	17	20,689,405 (GRCm39)	missense	probably damaging	1.00
IGL02939:Vmn2r108	APN	17	20,691,545 (GRCm39)	missense	probably benign	0.05
PIT4498001:Vmn2r108	UTSW	17	20,683,279 (GRCm39)	missense	probably damaging	1.00
R0112:Vmn2r108	UTSW	17	20,691,897 (GRCm39)	missense	probably benign	0.07
R0505:Vmn2r108	UTSW	17	20,683,096 (GRCm39)	missense	possibly damaging	0.77
R0833:Vmn2r108	UTSW	17	20,691,721 (GRCm39)	missense	probably benign
R0836:Vmn2r108	UTSW	17	20,691,721 (GRCm39)	missense	probably benign
R0943:Vmn2r108	UTSW	17	20,691,397 (GRCm39)	nonsense	probably null
R1411:Vmn2r108	UTSW	17	20,683,107 (GRCm39)	missense	probably damaging	0.98
R1442:Vmn2r108	UTSW	17	20,692,623 (GRCm39)	nonsense	probably null
R1587:Vmn2r108	UTSW	17	20,692,383 (GRCm39)	missense	probably damaging	1.00
R1751:Vmn2r108	UTSW	17	20,682,786 (GRCm39)	missense	probably damaging	1.00
R1773:Vmn2r108	UTSW	17	20,689,335 (GRCm39)	missense	probably damaging	1.00
R2021:Vmn2r108	UTSW	17	20,691,252 (GRCm39)	missense	probably benign	0.00
R2159:Vmn2r108	UTSW	17	20,689,363 (GRCm39)	missense	probably benign	0.41
R2224:Vmn2r108	UTSW	17	20,701,295 (GRCm39)	nonsense	probably null
R2226:Vmn2r108	UTSW	17	20,701,295 (GRCm39)	nonsense	probably null
R2517:Vmn2r108	UTSW	17	20,692,577 (GRCm39)	missense	probably damaging	1.00
R3710:Vmn2r108	UTSW	17	20,682,932 (GRCm39)	missense	probably benign
R4470:Vmn2r108	UTSW	17	20,682,990 (GRCm39)	missense	probably damaging	1.00
R4686:Vmn2r108	UTSW	17	20,691,636 (GRCm39)	missense	probably damaging	0.99
R4729:Vmn2r108	UTSW	17	20,692,632 (GRCm39)	missense	probably damaging	0.99
R4799:Vmn2r108	UTSW	17	20,682,891 (GRCm39)	missense	probably damaging	1.00
R4993:Vmn2r108	UTSW	17	20,701,449 (GRCm39)	missense	probably benign	0.04
R5088:Vmn2r108	UTSW	17	20,690,454 (GRCm39)	missense	possibly damaging	0.46
R5213:Vmn2r108	UTSW	17	20,691,755 (GRCm39)	missense	probably benign	0.00
R5289:Vmn2r108	UTSW	17	20,691,866 (GRCm39)	missense	probably damaging	1.00
R5290:Vmn2r108	UTSW	17	20,691,665 (GRCm39)	missense	probably benign	0.00
R5713:Vmn2r108	UTSW	17	20,691,290 (GRCm39)	missense	probably damaging	1.00
R5753:Vmn2r108	UTSW	17	20,683,179 (GRCm39)	missense	probably damaging	0.99
R5792:Vmn2r108	UTSW	17	20,683,398 (GRCm39)	missense	probably damaging	0.99
R5798:Vmn2r108	UTSW	17	20,692,545 (GRCm39)	missense	probably benign	0.39
R5897:Vmn2r108	UTSW	17	20,691,580 (GRCm39)	missense	probably benign	0.01
R6018:Vmn2r108	UTSW	17	20,683,268 (GRCm39)	missense	possibly damaging	0.83
R6093:Vmn2r108	UTSW	17	20,701,402 (GRCm39)	missense	probably benign	0.00
R6156:Vmn2r108	UTSW	17	20,692,447 (GRCm39)	missense	probably benign	0.03
R6199:Vmn2r108	UTSW	17	20,682,644 (GRCm39)	missense	probably benign	0.01
R6259:Vmn2r108	UTSW	17	20,683,371 (GRCm39)	missense	possibly damaging	0.95
R6309:Vmn2r108	UTSW	17	20,691,660 (GRCm39)	missense	probably damaging	0.98
R6324:Vmn2r108	UTSW	17	20,691,977 (GRCm39)	nonsense	probably null
R6364:Vmn2r108	UTSW	17	20,691,260 (GRCm39)	missense	probably benign	0.00
R6446:Vmn2r108	UTSW	17	20,692,609 (GRCm39)	nonsense	probably null
R6541:Vmn2r108	UTSW	17	20,701,480 (GRCm39)	missense	probably benign	0.02
R7025:Vmn2r108	UTSW	17	20,691,345 (GRCm39)	missense	possibly damaging	0.67
R7063:Vmn2r108	UTSW	17	20,701,410 (GRCm39)	missense	probably damaging	1.00
R7092:Vmn2r108	UTSW	17	20,701,338 (GRCm39)	missense	probably benign	0.10
R7096:Vmn2r108	UTSW	17	20,682,762 (GRCm39)	missense	probably damaging	1.00
R7203:Vmn2r108	UTSW	17	20,683,038 (GRCm39)	missense	probably benign	0.12
R7458:Vmn2r108	UTSW	17	20,692,532 (GRCm39)	missense	probably benign	0.17
R7619:Vmn2r108	UTSW	17	20,692,457 (GRCm39)	missense	probably benign	0.02
R7841:Vmn2r108	UTSW	17	20,690,305 (GRCm39)	critical splice donor site	probably null
R7944:Vmn2r108	UTSW	17	20,691,890 (GRCm39)	missense	probably damaging	0.99
R8048:Vmn2r108	UTSW	17	20,691,762 (GRCm39)	missense	probably benign	0.29
R8213:Vmn2r108	UTSW	17	20,690,350 (GRCm39)	missense	probably benign	0.03
R8218:Vmn2r108	UTSW	17	20,683,465 (GRCm39)	missense	probably damaging	1.00
R8507:Vmn2r108	UTSW	17	20,683,195 (GRCm39)	nonsense	probably null
R8708:Vmn2r108	UTSW	17	20,682,687 (GRCm39)	missense	probably damaging	0.98
R8845:Vmn2r108	UTSW	17	20,691,361 (GRCm39)	missense	probably benign	0.03
R9030:Vmn2r108	UTSW	17	20,690,312 (GRCm39)	missense	probably benign	0.01
R9226:Vmn2r108	UTSW	17	20,691,330 (GRCm39)	missense	probably benign
R9278:Vmn2r108	UTSW	17	20,692,561 (GRCm39)	missense	probably benign	0.11
X0022:Vmn2r108	UTSW	17	20,691,371 (GRCm39)	missense	probably damaging	1.00
Z1088:Vmn2r108	UTSW	17	20,691,375 (GRCm39)	missense	probably benign	0.01
Z1177:Vmn2r108	UTSW	17	20,691,219 (GRCm39)	missense	probably damaging	0.99

Posted On

2016-08-02