Incidental Mutation 'R0462:Flg2'
| ID |
41349 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Flg2
|
| Ensembl Gene |
ENSMUSG00000049133 |
| Gene Name |
filaggrin family member 2 |
| Synonyms |
EG229574 |
| MMRRC Submission |
038662-MU
|
| Accession Numbers |
|
| Essential gene? |
Probably non essential
(E-score: 0.126)
|
| Stock # |
R0462 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
3 |
| Chromosomal Location |
93104585-93128698 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to T
at 93108744 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Glutamic Acid to Aspartic acid
at position 257
(E257D)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000096482
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000098884]
[ENSMUST00000194707]
|
| AlphaFold |
no structure available at present |
| Predicted Effect |
probably benign
Transcript: ENSMUST00000098884
AA Change: E257D
PolyPhen 2
Score 0.178 (Sensitivity: 0.92; Specificity: 0.87)
|
| SMART Domains |
Protein: ENSMUSP00000096482
Gene: ENSMUSG00000049133
AA Change: E257D
| Domain | Start | End | E-Value | Type |
|---|
|
Pfam:S_100
|
4 |
46 |
1.2e-17 |
PFAM |
|
low complexity region
|
58 |
70 |
N/A |
INTRINSIC |
|
low complexity region
|
110 |
121 |
N/A |
INTRINSIC |
|
low complexity region
|
131 |
146 |
N/A |
INTRINSIC |
|
low complexity region
|
207 |
223 |
N/A |
INTRINSIC |
|
internal_repeat_2
|
230 |
347 |
7.36e-7 |
PROSPERO |
|
internal_repeat_2
|
349 |
466 |
7.36e-7 |
PROSPERO |
|
internal_repeat_3
|
366 |
392 |
6.93e-6 |
PROSPERO |
|
internal_repeat_6
|
419 |
471 |
4.17e-5 |
PROSPERO |
|
low complexity region
|
474 |
550 |
N/A |
INTRINSIC |
|
low complexity region
|
567 |
589 |
N/A |
INTRINSIC |
|
low complexity region
|
593 |
679 |
N/A |
INTRINSIC |
|
low complexity region
|
680 |
705 |
N/A |
INTRINSIC |
|
low complexity region
|
719 |
748 |
N/A |
INTRINSIC |
|
low complexity region
|
749 |
768 |
N/A |
INTRINSIC |
|
low complexity region
|
772 |
800 |
N/A |
INTRINSIC |
|
internal_repeat_5
|
804 |
825 |
4.17e-5 |
PROSPERO |
|
internal_repeat_3
|
810 |
836 |
6.93e-6 |
PROSPERO |
|
low complexity region
|
846 |
860 |
N/A |
INTRINSIC |
|
low complexity region
|
863 |
885 |
N/A |
INTRINSIC |
|
internal_repeat_5
|
895 |
919 |
4.17e-5 |
PROSPERO |
|
internal_repeat_4
|
899 |
939 |
1.7e-5 |
PROSPERO |
|
internal_repeat_1
|
944 |
1461 |
8.08e-127 |
PROSPERO |
|
internal_repeat_6
|
1335 |
1386 |
4.17e-5 |
PROSPERO |
|
low complexity region
|
1465 |
1485 |
N/A |
INTRINSIC |
|
internal_repeat_1
|
1486 |
2009 |
8.08e-127 |
PROSPERO |
|
internal_repeat_4
|
2123 |
2173 |
1.7e-5 |
PROSPERO |
|
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000194707
|
| SMART Domains |
Protein: ENSMUSP00000141201
Gene: ENSMUSG00000049133
| Domain | Start | End | E-Value | Type |
|---|
|
SCOP:d1qlka_
|
1 |
35 |
6e-10 |
SMART |
|
low complexity region
|
53 |
64 |
N/A |
INTRINSIC |
|
low complexity region
|
74 |
89 |
N/A |
INTRINSIC |
|
low complexity region
|
150 |
166 |
N/A |
INTRINSIC |
|
low complexity region
|
339 |
354 |
N/A |
INTRINSIC |
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.2%
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aarsd1 |
A |
T |
11: 101,304,917 (GRCm39) |
D190E |
probably damaging |
Het |
| Acnat2 |
A |
G |
4: 49,383,084 (GRCm39) |
|
probably null |
Het |
| Acot10 |
T |
G |
15: 20,666,712 (GRCm39) |
T10P |
possibly damaging |
Het |
| Aldh7a1 |
T |
C |
18: 56,667,286 (GRCm39) |
|
probably null |
Het |
| Alkbh7 |
G |
A |
17: 57,305,443 (GRCm39) |
V87I |
probably benign |
Het |
| Ano2 |
A |
T |
6: 125,689,238 (GRCm39) |
H121L |
probably benign |
Het |
| Apob |
A |
T |
12: 8,050,896 (GRCm39) |
Y1040F |
probably damaging |
Het |
| Arhgap25 |
A |
T |
6: 87,436,942 (GRCm39) |
V636E |
possibly damaging |
Het |
| Atad2b |
A |
T |
12: 4,991,973 (GRCm39) |
T191S |
possibly damaging |
Het |
| Atpsckmt |
T |
C |
15: 31,617,018 (GRCm39) |
M161T |
probably damaging |
Het |
| Btbd9 |
A |
T |
17: 30,749,191 (GRCm39) |
V41D |
possibly damaging |
Het |
| Bzw2 |
G |
A |
12: 36,174,023 (GRCm39) |
R25C |
probably damaging |
Het |
| Carmil1 |
T |
C |
13: 24,206,494 (GRCm39) |
S1326G |
probably benign |
Het |
| Cdh18 |
A |
G |
15: 23,366,971 (GRCm39) |
R226G |
probably damaging |
Het |
| Cdh3 |
A |
G |
8: 107,282,012 (GRCm39) |
N800S |
possibly damaging |
Het |
| Cep152 |
A |
T |
2: 125,425,854 (GRCm39) |
V837E |
possibly damaging |
Het |
| Cep85 |
G |
A |
4: 133,858,732 (GRCm39) |
T713M |
possibly damaging |
Het |
| Chd7 |
T |
C |
4: 8,850,821 (GRCm39) |
Y1736H |
probably damaging |
Het |
| Chst3 |
T |
C |
10: 60,022,535 (GRCm39) |
E104G |
probably benign |
Het |
| Cic |
T |
A |
7: 24,986,565 (GRCm39) |
S1299T |
probably damaging |
Het |
| Cic |
C |
A |
7: 24,986,566 (GRCm39) |
S1299Y |
probably damaging |
Het |
| Cmah |
T |
A |
13: 24,620,724 (GRCm39) |
S319R |
possibly damaging |
Het |
| Cnbd1 |
A |
G |
4: 18,895,044 (GRCm39) |
F233L |
probably benign |
Het |
| Cpne5 |
T |
C |
17: 29,395,163 (GRCm39) |
E251G |
probably benign |
Het |
| Csf2rb2 |
G |
A |
15: 78,169,373 (GRCm39) |
P485L |
probably damaging |
Het |
| Dimt1 |
T |
C |
13: 107,085,264 (GRCm39) |
M70T |
possibly damaging |
Het |
| Dlk2 |
A |
G |
17: 46,614,024 (GRCm39) |
*383W |
probably null |
Het |
| Dnah2 |
G |
A |
11: 69,350,027 (GRCm39) |
R2369C |
probably damaging |
Het |
| Dock2 |
A |
G |
11: 34,218,052 (GRCm39) |
F1173L |
possibly damaging |
Het |
| Dok7 |
A |
G |
5: 35,223,806 (GRCm39) |
H115R |
possibly damaging |
Het |
| Dpy19l1 |
A |
G |
9: 24,325,645 (GRCm39) |
I720T |
probably benign |
Het |
| Eps8 |
A |
T |
6: 137,491,309 (GRCm39) |
D356E |
probably benign |
Het |
| Exoc1 |
A |
G |
5: 76,691,464 (GRCm39) |
N263D |
probably benign |
Het |
| Fbxl3 |
T |
C |
14: 103,320,322 (GRCm39) |
D375G |
probably damaging |
Het |
| Fcgbpl1 |
A |
T |
7: 27,836,765 (GRCm39) |
D228V |
probably damaging |
Het |
| Fstl4 |
A |
G |
11: 53,077,229 (GRCm39) |
D662G |
probably benign |
Het |
| Gbp10 |
G |
T |
5: 105,366,390 (GRCm39) |
Q505K |
possibly damaging |
Het |
| Gemin2 |
C |
T |
12: 59,060,305 (GRCm39) |
P15S |
probably damaging |
Het |
| Grhl2 |
A |
G |
15: 37,344,919 (GRCm39) |
M514V |
probably benign |
Het |
| Hgs |
A |
G |
11: 120,369,970 (GRCm39) |
N413D |
possibly damaging |
Het |
| Il12rb2 |
T |
C |
6: 67,280,594 (GRCm39) |
S538G |
possibly damaging |
Het |
| Kdm5a |
A |
G |
6: 120,379,561 (GRCm39) |
D623G |
probably damaging |
Het |
| Kifbp |
A |
T |
10: 62,395,235 (GRCm39) |
I469N |
probably damaging |
Het |
| Matk |
G |
T |
10: 81,095,527 (GRCm39) |
V116F |
probably damaging |
Het |
| Mcm3 |
T |
C |
1: 20,875,556 (GRCm39) |
T694A |
probably benign |
Het |
| Mctp1 |
C |
A |
13: 76,949,520 (GRCm39) |
H260Q |
probably damaging |
Het |
| Mios |
T |
A |
6: 8,215,743 (GRCm39) |
I313K |
probably benign |
Het |
| Muc4 |
T |
A |
16: 32,582,910 (GRCm39) |
Y2562N |
possibly damaging |
Het |
| Naip5 |
T |
A |
13: 100,358,240 (GRCm39) |
I999F |
probably damaging |
Het |
| Or11h4 |
T |
A |
14: 50,974,554 (GRCm39) |
I22L |
probably benign |
Het |
| Or14j7 |
A |
T |
17: 38,234,667 (GRCm39) |
D70V |
probably damaging |
Het |
| Or1x6 |
A |
G |
11: 50,939,336 (GRCm39) |
Y134C |
probably damaging |
Het |
| Or52a5 |
A |
T |
7: 103,426,770 (GRCm39) |
S261T |
probably benign |
Het |
| Or7g12 |
A |
T |
9: 18,900,198 (GRCm39) |
I305F |
probably benign |
Het |
| Or8g52 |
T |
A |
9: 39,630,706 (GRCm39) |
F61Y |
probably benign |
Het |
| Pafah1b1 |
A |
G |
11: 74,568,541 (GRCm39) |
V396A |
probably benign |
Het |
| Pard6b |
T |
A |
2: 167,929,467 (GRCm39) |
I91N |
possibly damaging |
Het |
| Pdzd2 |
T |
C |
15: 12,592,246 (GRCm39) |
S133G |
probably damaging |
Het |
| Plcg2 |
T |
G |
8: 118,312,044 (GRCm39) |
S445R |
probably benign |
Het |
| Plekhd1 |
G |
T |
12: 80,768,352 (GRCm39) |
V396L |
probably damaging |
Het |
| Ppp4r2 |
A |
G |
6: 100,843,518 (GRCm39) |
D294G |
possibly damaging |
Het |
| Ppwd1 |
T |
C |
13: 104,359,468 (GRCm39) |
|
probably null |
Het |
| Prr22 |
A |
G |
17: 57,077,551 (GRCm39) |
|
probably benign |
Het |
| Psme4 |
A |
G |
11: 30,798,117 (GRCm39) |
D1370G |
probably damaging |
Het |
| Rac3 |
T |
A |
11: 120,613,684 (GRCm39) |
V86D |
probably damaging |
Het |
| Rnf207 |
T |
C |
4: 152,397,829 (GRCm39) |
S335G |
possibly damaging |
Het |
| Rxfp3 |
A |
G |
15: 11,037,063 (GRCm39) |
L103P |
probably damaging |
Het |
| Slc17a3 |
C |
T |
13: 24,039,841 (GRCm39) |
S293F |
probably damaging |
Het |
| Smpdl3a |
G |
T |
10: 57,670,827 (GRCm39) |
C17F |
probably benign |
Het |
| Spaca7b |
T |
A |
8: 11,711,749 (GRCm39) |
|
probably benign |
Het |
| Spata31g1 |
T |
A |
4: 42,973,429 (GRCm39) |
F921I |
probably benign |
Het |
| Spen |
A |
T |
4: 141,200,962 (GRCm39) |
I2555N |
probably damaging |
Het |
| Srpk2 |
G |
T |
5: 23,723,424 (GRCm39) |
T564K |
probably damaging |
Het |
| Stard4 |
C |
T |
18: 33,338,202 (GRCm39) |
R116H |
probably damaging |
Het |
| Supt7l |
A |
T |
5: 31,677,640 (GRCm39) |
S175R |
probably damaging |
Het |
| Sycp1 |
A |
T |
3: 102,726,422 (GRCm39) |
Y932N |
possibly damaging |
Het |
| Tas2r122 |
T |
C |
6: 132,688,141 (GRCm39) |
M251V |
probably benign |
Het |
| Tbx15 |
A |
T |
3: 99,223,634 (GRCm39) |
E274V |
probably damaging |
Het |
| Tex52 |
A |
G |
6: 128,361,917 (GRCm39) |
E298G |
probably benign |
Het |
| Tmem101 |
T |
C |
11: 102,046,693 (GRCm39) |
M59V |
probably benign |
Het |
| Tmem132b |
T |
C |
5: 125,862,990 (GRCm39) |
V665A |
probably damaging |
Het |
| Trim23 |
T |
C |
13: 104,334,541 (GRCm39) |
V347A |
probably damaging |
Het |
| Ush2a |
A |
G |
1: 188,643,136 (GRCm39) |
H4166R |
probably benign |
Het |
| Vmn2r101 |
G |
T |
17: 19,810,431 (GRCm39) |
V406L |
probably benign |
Het |
| Vrk3 |
A |
G |
7: 44,413,624 (GRCm39) |
D166G |
possibly damaging |
Het |
| Washc4 |
T |
A |
10: 83,392,777 (GRCm39) |
M259K |
probably benign |
Het |
| Wdr70 |
T |
C |
15: 8,108,645 (GRCm39) |
D167G |
probably benign |
Het |
| Zfp1005 |
A |
G |
2: 150,111,122 (GRCm39) |
E604G |
possibly damaging |
Het |
| Zfp28 |
A |
T |
7: 6,395,239 (GRCm39) |
Q248L |
possibly damaging |
Het |
| Zfp39 |
A |
G |
11: 58,781,232 (GRCm39) |
I510T |
probably benign |
Het |
| Zfp710 |
T |
A |
7: 79,740,089 (GRCm39) |
*646R |
probably null |
Het |
| Zfp90 |
C |
T |
8: 107,151,892 (GRCm39) |
S535L |
possibly damaging |
Het |
| Zfp949 |
C |
T |
9: 88,450,787 (GRCm39) |
T119I |
possibly damaging |
Het |
|
| Other mutations in Flg2 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00090:Flg2
|
APN |
3 |
93,109,416 (GRCm39) |
nonsense |
probably null |
|
|
IGL00092:Flg2
|
APN |
3 |
93,127,162 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
IGL00985:Flg2
|
APN |
3 |
93,110,585 (GRCm39) |
missense |
unknown |
|
|
IGL01077:Flg2
|
APN |
3 |
93,127,513 (GRCm39) |
missense |
unknown |
|
|
IGL01093:Flg2
|
APN |
3 |
93,109,678 (GRCm39) |
missense |
unknown |
|
|
IGL01120:Flg2
|
APN |
3 |
93,108,475 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL01473:Flg2
|
APN |
3 |
93,110,327 (GRCm39) |
missense |
unknown |
|
|
IGL01584:Flg2
|
APN |
3 |
93,122,777 (GRCm39) |
missense |
unknown |
|
|
IGL01584:Flg2
|
APN |
3 |
93,120,773 (GRCm39) |
missense |
unknown |
|
|
IGL01686:Flg2
|
APN |
3 |
93,109,591 (GRCm39) |
missense |
unknown |
|
|
IGL02207:Flg2
|
APN |
3 |
93,127,435 (GRCm39) |
missense |
unknown |
|
|
IGL02294:Flg2
|
APN |
3 |
93,111,053 (GRCm39) |
missense |
unknown |
|
|
IGL02418:Flg2
|
APN |
3 |
93,108,361 (GRCm39) |
missense |
probably benign |
0.26 |
|
IGL02581:Flg2
|
APN |
3 |
93,127,199 (GRCm39) |
missense |
unknown |
|
|
IGL02719:Flg2
|
APN |
3 |
93,127,438 (GRCm39) |
nonsense |
probably null |
|
|
IGL02795:Flg2
|
APN |
3 |
93,110,920 (GRCm39) |
missense |
unknown |
|
|
IGL02893:Flg2
|
APN |
3 |
93,110,920 (GRCm39) |
missense |
unknown |
|
|
IGL02958:Flg2
|
APN |
3 |
93,110,920 (GRCm39) |
missense |
unknown |
|
|
IGL03060:Flg2
|
APN |
3 |
93,110,920 (GRCm39) |
missense |
unknown |
|
|
IGL03088:Flg2
|
APN |
3 |
93,110,498 (GRCm39) |
missense |
unknown |
|
|
IGL03165:Flg2
|
APN |
3 |
93,121,918 (GRCm39) |
missense |
unknown |
|
|
IGL03342:Flg2
|
APN |
3 |
93,108,542 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03352:Flg2
|
APN |
3 |
93,109,801 (GRCm39) |
missense |
unknown |
|
|
IGL02796:Flg2
|
UTSW |
3 |
93,110,920 (GRCm39) |
missense |
unknown |
|
|
IGL02837:Flg2
|
UTSW |
3 |
93,109,044 (GRCm39) |
missense |
probably damaging |
1.00 |
|
PIT4618001:Flg2
|
UTSW |
3 |
93,111,088 (GRCm39) |
missense |
unknown |
|
|
R0087:Flg2
|
UTSW |
3 |
93,109,738 (GRCm39) |
missense |
unknown |
|
|
R0233:Flg2
|
UTSW |
3 |
93,109,104 (GRCm39) |
nonsense |
probably null |
|
|
R0233:Flg2
|
UTSW |
3 |
93,109,104 (GRCm39) |
nonsense |
probably null |
|
|
R0315:Flg2
|
UTSW |
3 |
93,122,029 (GRCm39) |
missense |
unknown |
|
|
R0390:Flg2
|
UTSW |
3 |
93,107,662 (GRCm39) |
splice site |
probably benign |
|
|
R0553:Flg2
|
UTSW |
3 |
93,110,891 (GRCm39) |
missense |
unknown |
|
|
R0828:Flg2
|
UTSW |
3 |
93,110,639 (GRCm39) |
missense |
unknown |
|
|
R1006:Flg2
|
UTSW |
3 |
93,108,514 (GRCm39) |
missense |
probably benign |
0.41 |
|
R1444:Flg2
|
UTSW |
3 |
93,109,620 (GRCm39) |
missense |
unknown |
|
|
R1497:Flg2
|
UTSW |
3 |
93,127,076 (GRCm39) |
missense |
unknown |
|
|
R1518:Flg2
|
UTSW |
3 |
93,110,445 (GRCm39) |
missense |
unknown |
|
|
R1737:Flg2
|
UTSW |
3 |
93,110,928 (GRCm39) |
missense |
unknown |
|
|
R1780:Flg2
|
UTSW |
3 |
93,110,306 (GRCm39) |
missense |
unknown |
|
|
R1797:Flg2
|
UTSW |
3 |
93,108,283 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2065:Flg2
|
UTSW |
3 |
93,109,538 (GRCm39) |
missense |
unknown |
|
|
R2168:Flg2
|
UTSW |
3 |
93,109,244 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R2220:Flg2
|
UTSW |
3 |
93,109,492 (GRCm39) |
missense |
unknown |
|
|
R2292:Flg2
|
UTSW |
3 |
93,127,984 (GRCm39) |
missense |
unknown |
|
|
R2327:Flg2
|
UTSW |
3 |
93,110,913 (GRCm39) |
nonsense |
probably null |
|
|
R2512:Flg2
|
UTSW |
3 |
93,109,082 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R3177:Flg2
|
UTSW |
3 |
93,122,195 (GRCm39) |
missense |
unknown |
|
|
R3277:Flg2
|
UTSW |
3 |
93,122,195 (GRCm39) |
missense |
unknown |
|
|
R3522:Flg2
|
UTSW |
3 |
93,127,334 (GRCm39) |
missense |
unknown |
|
|
R3779:Flg2
|
UTSW |
3 |
93,109,730 (GRCm39) |
missense |
unknown |
|
|
R3926:Flg2
|
UTSW |
3 |
93,110,522 (GRCm39) |
missense |
unknown |
|
|
R4082:Flg2
|
UTSW |
3 |
93,110,828 (GRCm39) |
missense |
unknown |
|
|
R4407:Flg2
|
UTSW |
3 |
93,122,176 (GRCm39) |
missense |
unknown |
|
|
R5152:Flg2
|
UTSW |
3 |
93,122,284 (GRCm39) |
missense |
unknown |
|
|
R5253:Flg2
|
UTSW |
3 |
93,108,119 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5290:Flg2
|
UTSW |
3 |
93,127,873 (GRCm39) |
missense |
unknown |
|
|
R5464:Flg2
|
UTSW |
3 |
93,109,277 (GRCm39) |
missense |
possibly damaging |
0.73 |
|
R5539:Flg2
|
UTSW |
3 |
93,127,753 (GRCm39) |
missense |
unknown |
|
|
R5622:Flg2
|
UTSW |
3 |
93,109,871 (GRCm39) |
missense |
unknown |
|
|
R5788:Flg2
|
UTSW |
3 |
93,108,296 (GRCm39) |
missense |
probably benign |
0.41 |
|
R5792:Flg2
|
UTSW |
3 |
93,110,804 (GRCm39) |
missense |
unknown |
|
|
R5831:Flg2
|
UTSW |
3 |
93,107,541 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5877:Flg2
|
UTSW |
3 |
93,110,756 (GRCm39) |
missense |
unknown |
|
|
R6041:Flg2
|
UTSW |
3 |
93,127,668 (GRCm39) |
missense |
probably benign |
0.01 |
|
R6189:Flg2
|
UTSW |
3 |
93,127,381 (GRCm39) |
missense |
unknown |
|
|
R6214:Flg2
|
UTSW |
3 |
93,109,166 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6215:Flg2
|
UTSW |
3 |
93,109,166 (GRCm39) |
missense |
possibly damaging |
0.83 |
|
R6239:Flg2
|
UTSW |
3 |
93,108,579 (GRCm39) |
missense |
probably benign |
0.36 |
|
R6288:Flg2
|
UTSW |
3 |
93,111,092 (GRCm39) |
missense |
unknown |
|
|
R6413:Flg2
|
UTSW |
3 |
93,127,683 (GRCm39) |
missense |
unknown |
|
|
R6457:Flg2
|
UTSW |
3 |
93,127,789 (GRCm39) |
missense |
unknown |
|
|
R6468:Flg2
|
UTSW |
3 |
93,121,728 (GRCm39) |
missense |
unknown |
|
|
R6667:Flg2
|
UTSW |
3 |
93,109,068 (GRCm39) |
missense |
possibly damaging |
0.88 |
|
R6930:Flg2
|
UTSW |
3 |
93,108,642 (GRCm39) |
nonsense |
probably null |
|
|
R6996:Flg2
|
UTSW |
3 |
93,110,256 (GRCm39) |
missense |
unknown |
|
|
R6996:Flg2
|
UTSW |
3 |
93,109,977 (GRCm39) |
missense |
unknown |
|
|
R7100:Flg2
|
UTSW |
3 |
93,111,018 (GRCm39) |
missense |
unknown |
|
|
R7133:Flg2
|
UTSW |
3 |
93,127,069 (GRCm39) |
missense |
unknown |
|
|
R7180:Flg2
|
UTSW |
3 |
93,110,140 (GRCm39) |
missense |
unknown |
|
|
R7325:Flg2
|
UTSW |
3 |
93,110,679 (GRCm39) |
missense |
unknown |
|
|
R7349:Flg2
|
UTSW |
3 |
93,127,513 (GRCm39) |
missense |
unknown |
|
|
R7531:Flg2
|
UTSW |
3 |
93,108,177 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7571:Flg2
|
UTSW |
3 |
93,127,303 (GRCm39) |
nonsense |
probably null |
|
|
R7684:Flg2
|
UTSW |
3 |
93,126,956 (GRCm39) |
missense |
unknown |
|
|
R7810:Flg2
|
UTSW |
3 |
93,107,548 (GRCm39) |
missense |
possibly damaging |
0.70 |
|
R7853:Flg2
|
UTSW |
3 |
93,128,054 (GRCm39) |
missense |
unknown |
|
|
R8031:Flg2
|
UTSW |
3 |
93,127,521 (GRCm39) |
missense |
unknown |
|
|
R8078:Flg2
|
UTSW |
3 |
93,107,582 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8142:Flg2
|
UTSW |
3 |
93,122,782 (GRCm39) |
nonsense |
probably null |
|
|
R8156:Flg2
|
UTSW |
3 |
93,127,390 (GRCm39) |
missense |
unknown |
|
|
R8172:Flg2
|
UTSW |
3 |
93,108,468 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
R8204:Flg2
|
UTSW |
3 |
93,110,074 (GRCm39) |
missense |
unknown |
|
|
R8262:Flg2
|
UTSW |
3 |
93,127,517 (GRCm39) |
missense |
unknown |
|
|
R8269:Flg2
|
UTSW |
3 |
93,109,187 (GRCm39) |
missense |
possibly damaging |
0.68 |
|
R8290:Flg2
|
UTSW |
3 |
93,110,069 (GRCm39) |
missense |
unknown |
|
|
R8444:Flg2
|
UTSW |
3 |
93,107,585 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8670:Flg2
|
UTSW |
3 |
93,108,791 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R8755:Flg2
|
UTSW |
3 |
93,108,120 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9039:Flg2
|
UTSW |
3 |
93,110,899 (GRCm39) |
missense |
unknown |
|
|
R9116:Flg2
|
UTSW |
3 |
93,109,591 (GRCm39) |
missense |
unknown |
|
|
R9214:Flg2
|
UTSW |
3 |
93,110,884 (GRCm39) |
missense |
unknown |
|
|
R9231:Flg2
|
UTSW |
3 |
93,109,508 (GRCm39) |
missense |
unknown |
|
|
R9553:Flg2
|
UTSW |
3 |
93,121,901 (GRCm39) |
missense |
unknown |
|
|
R9607:Flg2
|
UTSW |
3 |
93,108,719 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R9735:Flg2
|
UTSW |
3 |
93,127,669 (GRCm39) |
missense |
unknown |
|
|
R9752:Flg2
|
UTSW |
3 |
93,108,467 (GRCm39) |
missense |
probably damaging |
0.98 |
|
Z1177:Flg2
|
UTSW |
3 |
93,110,045 (GRCm39) |
missense |
unknown |
|
|
Z1177:Flg2
|
UTSW |
3 |
93,109,727 (GRCm39) |
missense |
unknown |
|
|
| Predicted Primers |
PCR Primer
(F):5'- TCACGGGGACCTGCAAAACATAG -3'
(R):5'- AGAGGACTGACCTTCTGAGACACAC -3'
Sequencing Primer
(F):5'- GGCAAGATGAATTATCCAGCTC -3'
(R):5'- CACTAGTTCCTGATTGACAGTTTGAC -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation