Incidental Mutation 'IGL03221:Lilr4b'
ID413666
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Lilr4b
Ensembl Gene ENSMUSG00000112023
Gene Nameleukocyte immunoglobulin-like receptor, subfamily B, member 4B
SynonymsGp49a, gp49
Accession Numbers
Is this an essential gene? Probably non essential (E-score: 0.191) question?
Stock #IGL03221
Quality Score
Status
Chromosome10
Chromosomal Location51480632-51486703 bp(+) (GRCm38)
Type of Mutationsplice site
DNA Base Change (assembly) A to G at 51481428 bp
ZygosityHeterozygous
Amino Acid Change
Ref Sequence ENSEMBL: ENSMUSP00000151563 (fasta)
Gene Model predicted gene model for transcript(s): [ENSMUST00000102894] [ENSMUST00000217706] [ENSMUST00000218123] [ENSMUST00000218704] [ENSMUST00000219661] [ENSMUST00000219696] [ENSMUST00000219960]
Predicted Effect probably benign
Transcript: ENSMUST00000102894
SMART Domains Protein: ENSMUSP00000099958
Gene: ENSMUSG00000112023

DomainStartEndE-ValueType
signal peptide 1 23 N/A INTRINSIC
SCOP:d1nkr_2 24 118 3e-14 SMART
Blast:IG_like 28 118 5e-49 BLAST
Pfam:Ig_3 123 200 6.5e-8 PFAM
Pfam:Ig_2 123 218 5.9e-8 PFAM
Pfam:ig 127 211 8.4e-9 PFAM
transmembrane domain 239 261 N/A INTRINSIC
Predicted Effect noncoding transcript
Transcript: ENSMUST00000139982
Predicted Effect probably benign
Transcript: ENSMUST00000217706
Predicted Effect probably benign
Transcript: ENSMUST00000218123
Predicted Effect noncoding transcript
Transcript: ENSMUST00000218179
Predicted Effect noncoding transcript
Transcript: ENSMUST00000218649
Predicted Effect probably benign
Transcript: ENSMUST00000218704
Predicted Effect noncoding transcript
Transcript: ENSMUST00000218900
Predicted Effect noncoding transcript
Transcript: ENSMUST00000219053
Predicted Effect noncoding transcript
Transcript: ENSMUST00000219151
Predicted Effect noncoding transcript
Transcript: ENSMUST00000219178
Predicted Effect noncoding transcript
Transcript: ENSMUST00000219262
Predicted Effect noncoding transcript
Transcript: ENSMUST00000219598
Predicted Effect probably benign
Transcript: ENSMUST00000219661
Predicted Effect probably benign
Transcript: ENSMUST00000219696
Predicted Effect noncoding transcript
Transcript: ENSMUST00000219717
Predicted Effect probably benign
Transcript: ENSMUST00000219960
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 30 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Atp2b2 C T 6: 113,760,859 probably benign Het
BC051665 T A 13: 60,784,428 K116* probably null Het
Birc6 A T 17: 74,627,007 T2538S probably benign Het
Btn2a2 A G 13: 23,478,449 S435P probably damaging Het
Efhb A G 17: 53,398,986 L841P probably damaging Het
Etv4 C T 11: 101,774,162 R155K probably damaging Het
Fam126b C A 1: 58,540,186 V231L probably benign Het
Fnbp4 T A 2: 90,777,718 M928K possibly damaging Het
Grin2c A G 11: 115,254,044 probably benign Het
Grip1 A T 10: 119,986,394 M342L probably benign Het
H60c T A 10: 3,259,799 K163* probably null Het
Lyl1 C T 8: 84,702,671 P3L possibly damaging Het
Mast4 A G 13: 102,754,256 V838A possibly damaging Het
Mypn C A 10: 63,131,123 D925Y probably damaging Het
Nol6 T C 4: 41,124,166 D27G probably benign Het
Olfr1202 T C 2: 88,817,437 S89P possibly damaging Het
Olfr1447 G T 19: 12,901,541 P80T probably damaging Het
Olfr916 A T 9: 38,658,365 V9E probably damaging Het
Pik3c2g A G 6: 139,772,407 probably null Het
Pik3c3 G T 18: 30,302,931 M394I probably benign Het
Rfx7 C T 9: 72,618,806 R1093C probably damaging Het
Scin A G 12: 40,076,974 V458A probably benign Het
Slc34a1 T C 13: 55,400,778 V39A probably benign Het
Slc6a4 A G 11: 77,027,105 M558V probably benign Het
Smpx T C X: 157,720,998 V65A probably damaging Het
Tmem200a A T 10: 25,994,024 F116I possibly damaging Het
Tnfrsf19 A T 14: 61,024,778 V12E probably benign Het
Trpc1 C T 9: 95,706,900 R757H probably damaging Het
Ttc38 T A 15: 85,834,541 S51T probably benign Het
Wee1 G A 7: 110,126,817 C378Y probably damaging Het
Other mutations in Lilr4b
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL00323:Lilr4b APN 10 51481251 missense probably benign 0.00
IGL02457:Lilr4b APN 10 51481238 missense probably benign 0.04
IGL03396:Lilr4b APN 10 51481157 missense possibly damaging 0.71
R0145:Lilr4b UTSW 10 51484518 missense probably benign 0.00
R0336:Lilr4b UTSW 10 51481293 missense probably benign 0.28
R1313:Lilr4b UTSW 10 51480736 missense probably benign 0.25
R1543:Lilr4b UTSW 10 51481421 missense probably damaging 0.98
R1984:Lilr4b UTSW 10 51481735 missense possibly damaging 0.68
R1985:Lilr4b UTSW 10 51481735 missense possibly damaging 0.68
R2243:Lilr4b UTSW 10 51481608 missense possibly damaging 0.88
R4094:Lilr4b UTSW 10 51481410 missense probably damaging 0.99
R4887:Lilr4b UTSW 10 51484520 missense possibly damaging 0.81
R5588:Lilr4b UTSW 10 51481326 missense probably benign
R6404:Lilr4b UTSW 10 51485729 missense probably damaging 0.99
Posted On2016-08-02