Incidental Mutation 'R0462:Psme4'
| ID |
41399 |
| Institutional Source |
Beutler Lab
|
| Gene Symbol |
Psme4
|
| Ensembl Gene |
ENSMUSG00000040850 |
| Gene Name |
proteasome (prosome, macropain) activator subunit 4 |
| Synonyms |
|
| MMRRC Submission |
038662-MU
|
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
R0462 (G1)
|
| Quality Score |
225 |
|
Status
|
Not validated
|
| Chromosome |
11 |
| Chromosomal Location |
30721726-30830361 bp(+) (GRCm39) |
| Type of Mutation |
missense |
| DNA Base Change (assembly) |
A to G
at 30798117 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
Aspartic acid to Glycine
at position 1370
(D1370G)
|
| Ref Sequence |
ENSEMBL: ENSMUSP00000045460
(fasta)
|
| Gene Model |
predicted gene model for transcript(s):
[ENSMUST00000041231]
[ENSMUST00000129824]
|
| AlphaFold |
Q5SSW2 |
| Predicted Effect |
probably damaging
Transcript: ENSMUST00000041231
AA Change: D1370G
PolyPhen 2
Score 0.998 (Sensitivity: 0.27; Specificity: 0.99)
|
| SMART Domains |
Protein: ENSMUSP00000045460
Gene: ENSMUSG00000040850
AA Change: D1370G
| Domain | Start | End | E-Value | Type |
|---|
|
low complexity region
|
2 |
19 |
N/A |
INTRINSIC |
|
low complexity region
|
122 |
133 |
N/A |
INTRINSIC |
|
Pfam:BLM10_mid
|
330 |
828 |
8.8e-119 |
PFAM |
|
SCOP:d1b3ua_
|
1183 |
1716 |
3e-14 |
SMART |
|
Pfam:DUF3437
|
1756 |
1843 |
5.3e-39 |
PFAM |
|
| Predicted Effect |
probably benign
Transcript: ENSMUST00000129824
|
| Coding Region Coverage |
- 1x: 99.2%
- 3x: 98.4%
- 10x: 96.5%
- 20x: 93.2%
|
| Validation Efficiency |
|
| MGI Phenotype |
PHENOTYPE: Mice homozygous for a knock-out allele show normal repair of DNA double-strand breaks but exhibit significantly reduced male fertility due to defects in spermatogenesis observed in both meiotic spermatocytes and postmeiotic haploid spermatids. [provided by MGI curators]
|
| Allele List at MGI |
All alleles(25) : Targeted, knock-out(1) Gene trapped(24) |
| Other mutations in this stock |
Total: 93 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Aarsd1 |
A |
T |
11: 101,304,917 (GRCm39) |
D190E |
probably damaging |
Het |
| Acnat2 |
A |
G |
4: 49,383,084 (GRCm39) |
|
probably null |
Het |
| Acot10 |
T |
G |
15: 20,666,712 (GRCm39) |
T10P |
possibly damaging |
Het |
| Aldh7a1 |
T |
C |
18: 56,667,286 (GRCm39) |
|
probably null |
Het |
| Alkbh7 |
G |
A |
17: 57,305,443 (GRCm39) |
V87I |
probably benign |
Het |
| Ano2 |
A |
T |
6: 125,689,238 (GRCm39) |
H121L |
probably benign |
Het |
| Apob |
A |
T |
12: 8,050,896 (GRCm39) |
Y1040F |
probably damaging |
Het |
| Arhgap25 |
A |
T |
6: 87,436,942 (GRCm39) |
V636E |
possibly damaging |
Het |
| Atad2b |
A |
T |
12: 4,991,973 (GRCm39) |
T191S |
possibly damaging |
Het |
| Atpsckmt |
T |
C |
15: 31,617,018 (GRCm39) |
M161T |
probably damaging |
Het |
| Btbd9 |
A |
T |
17: 30,749,191 (GRCm39) |
V41D |
possibly damaging |
Het |
| Bzw2 |
G |
A |
12: 36,174,023 (GRCm39) |
R25C |
probably damaging |
Het |
| Carmil1 |
T |
C |
13: 24,206,494 (GRCm39) |
S1326G |
probably benign |
Het |
| Cdh18 |
A |
G |
15: 23,366,971 (GRCm39) |
R226G |
probably damaging |
Het |
| Cdh3 |
A |
G |
8: 107,282,012 (GRCm39) |
N800S |
possibly damaging |
Het |
| Cep152 |
A |
T |
2: 125,425,854 (GRCm39) |
V837E |
possibly damaging |
Het |
| Cep85 |
G |
A |
4: 133,858,732 (GRCm39) |
T713M |
possibly damaging |
Het |
| Chd7 |
T |
C |
4: 8,850,821 (GRCm39) |
Y1736H |
probably damaging |
Het |
| Chst3 |
T |
C |
10: 60,022,535 (GRCm39) |
E104G |
probably benign |
Het |
| Cic |
T |
A |
7: 24,986,565 (GRCm39) |
S1299T |
probably damaging |
Het |
| Cic |
C |
A |
7: 24,986,566 (GRCm39) |
S1299Y |
probably damaging |
Het |
| Cmah |
T |
A |
13: 24,620,724 (GRCm39) |
S319R |
possibly damaging |
Het |
| Cnbd1 |
A |
G |
4: 18,895,044 (GRCm39) |
F233L |
probably benign |
Het |
| Cpne5 |
T |
C |
17: 29,395,163 (GRCm39) |
E251G |
probably benign |
Het |
| Csf2rb2 |
G |
A |
15: 78,169,373 (GRCm39) |
P485L |
probably damaging |
Het |
| Dimt1 |
T |
C |
13: 107,085,264 (GRCm39) |
M70T |
possibly damaging |
Het |
| Dlk2 |
A |
G |
17: 46,614,024 (GRCm39) |
*383W |
probably null |
Het |
| Dnah2 |
G |
A |
11: 69,350,027 (GRCm39) |
R2369C |
probably damaging |
Het |
| Dock2 |
A |
G |
11: 34,218,052 (GRCm39) |
F1173L |
possibly damaging |
Het |
| Dok7 |
A |
G |
5: 35,223,806 (GRCm39) |
H115R |
possibly damaging |
Het |
| Dpy19l1 |
A |
G |
9: 24,325,645 (GRCm39) |
I720T |
probably benign |
Het |
| Eps8 |
A |
T |
6: 137,491,309 (GRCm39) |
D356E |
probably benign |
Het |
| Exoc1 |
A |
G |
5: 76,691,464 (GRCm39) |
N263D |
probably benign |
Het |
| Fbxl3 |
T |
C |
14: 103,320,322 (GRCm39) |
D375G |
probably damaging |
Het |
| Fcgbpl1 |
A |
T |
7: 27,836,765 (GRCm39) |
D228V |
probably damaging |
Het |
| Flg2 |
A |
T |
3: 93,108,744 (GRCm39) |
E257D |
probably benign |
Het |
| Fstl4 |
A |
G |
11: 53,077,229 (GRCm39) |
D662G |
probably benign |
Het |
| Gbp10 |
G |
T |
5: 105,366,390 (GRCm39) |
Q505K |
possibly damaging |
Het |
| Gemin2 |
C |
T |
12: 59,060,305 (GRCm39) |
P15S |
probably damaging |
Het |
| Grhl2 |
A |
G |
15: 37,344,919 (GRCm39) |
M514V |
probably benign |
Het |
| Hgs |
A |
G |
11: 120,369,970 (GRCm39) |
N413D |
possibly damaging |
Het |
| Il12rb2 |
T |
C |
6: 67,280,594 (GRCm39) |
S538G |
possibly damaging |
Het |
| Kdm5a |
A |
G |
6: 120,379,561 (GRCm39) |
D623G |
probably damaging |
Het |
| Kifbp |
A |
T |
10: 62,395,235 (GRCm39) |
I469N |
probably damaging |
Het |
| Matk |
G |
T |
10: 81,095,527 (GRCm39) |
V116F |
probably damaging |
Het |
| Mcm3 |
T |
C |
1: 20,875,556 (GRCm39) |
T694A |
probably benign |
Het |
| Mctp1 |
C |
A |
13: 76,949,520 (GRCm39) |
H260Q |
probably damaging |
Het |
| Mios |
T |
A |
6: 8,215,743 (GRCm39) |
I313K |
probably benign |
Het |
| Muc4 |
T |
A |
16: 32,582,910 (GRCm39) |
Y2562N |
possibly damaging |
Het |
| Naip5 |
T |
A |
13: 100,358,240 (GRCm39) |
I999F |
probably damaging |
Het |
| Or11h4 |
T |
A |
14: 50,974,554 (GRCm39) |
I22L |
probably benign |
Het |
| Or14j7 |
A |
T |
17: 38,234,667 (GRCm39) |
D70V |
probably damaging |
Het |
| Or1x6 |
A |
G |
11: 50,939,336 (GRCm39) |
Y134C |
probably damaging |
Het |
| Or52a5 |
A |
T |
7: 103,426,770 (GRCm39) |
S261T |
probably benign |
Het |
| Or7g12 |
A |
T |
9: 18,900,198 (GRCm39) |
I305F |
probably benign |
Het |
| Or8g52 |
T |
A |
9: 39,630,706 (GRCm39) |
F61Y |
probably benign |
Het |
| Pafah1b1 |
A |
G |
11: 74,568,541 (GRCm39) |
V396A |
probably benign |
Het |
| Pard6b |
T |
A |
2: 167,929,467 (GRCm39) |
I91N |
possibly damaging |
Het |
| Pdzd2 |
T |
C |
15: 12,592,246 (GRCm39) |
S133G |
probably damaging |
Het |
| Plcg2 |
T |
G |
8: 118,312,044 (GRCm39) |
S445R |
probably benign |
Het |
| Plekhd1 |
G |
T |
12: 80,768,352 (GRCm39) |
V396L |
probably damaging |
Het |
| Ppp4r2 |
A |
G |
6: 100,843,518 (GRCm39) |
D294G |
possibly damaging |
Het |
| Ppwd1 |
T |
C |
13: 104,359,468 (GRCm39) |
|
probably null |
Het |
| Prr22 |
A |
G |
17: 57,077,551 (GRCm39) |
|
probably benign |
Het |
| Rac3 |
T |
A |
11: 120,613,684 (GRCm39) |
V86D |
probably damaging |
Het |
| Rnf207 |
T |
C |
4: 152,397,829 (GRCm39) |
S335G |
possibly damaging |
Het |
| Rxfp3 |
A |
G |
15: 11,037,063 (GRCm39) |
L103P |
probably damaging |
Het |
| Slc17a3 |
C |
T |
13: 24,039,841 (GRCm39) |
S293F |
probably damaging |
Het |
| Smpdl3a |
G |
T |
10: 57,670,827 (GRCm39) |
C17F |
probably benign |
Het |
| Spaca7b |
T |
A |
8: 11,711,749 (GRCm39) |
|
probably benign |
Het |
| Spata31g1 |
T |
A |
4: 42,973,429 (GRCm39) |
F921I |
probably benign |
Het |
| Spen |
A |
T |
4: 141,200,962 (GRCm39) |
I2555N |
probably damaging |
Het |
| Srpk2 |
G |
T |
5: 23,723,424 (GRCm39) |
T564K |
probably damaging |
Het |
| Stard4 |
C |
T |
18: 33,338,202 (GRCm39) |
R116H |
probably damaging |
Het |
| Supt7l |
A |
T |
5: 31,677,640 (GRCm39) |
S175R |
probably damaging |
Het |
| Sycp1 |
A |
T |
3: 102,726,422 (GRCm39) |
Y932N |
possibly damaging |
Het |
| Tas2r122 |
T |
C |
6: 132,688,141 (GRCm39) |
M251V |
probably benign |
Het |
| Tbx15 |
A |
T |
3: 99,223,634 (GRCm39) |
E274V |
probably damaging |
Het |
| Tex52 |
A |
G |
6: 128,361,917 (GRCm39) |
E298G |
probably benign |
Het |
| Tmem101 |
T |
C |
11: 102,046,693 (GRCm39) |
M59V |
probably benign |
Het |
| Tmem132b |
T |
C |
5: 125,862,990 (GRCm39) |
V665A |
probably damaging |
Het |
| Trim23 |
T |
C |
13: 104,334,541 (GRCm39) |
V347A |
probably damaging |
Het |
| Ush2a |
A |
G |
1: 188,643,136 (GRCm39) |
H4166R |
probably benign |
Het |
| Vmn2r101 |
G |
T |
17: 19,810,431 (GRCm39) |
V406L |
probably benign |
Het |
| Vrk3 |
A |
G |
7: 44,413,624 (GRCm39) |
D166G |
possibly damaging |
Het |
| Washc4 |
T |
A |
10: 83,392,777 (GRCm39) |
M259K |
probably benign |
Het |
| Wdr70 |
T |
C |
15: 8,108,645 (GRCm39) |
D167G |
probably benign |
Het |
| Zfp1005 |
A |
G |
2: 150,111,122 (GRCm39) |
E604G |
possibly damaging |
Het |
| Zfp28 |
A |
T |
7: 6,395,239 (GRCm39) |
Q248L |
possibly damaging |
Het |
| Zfp39 |
A |
G |
11: 58,781,232 (GRCm39) |
I510T |
probably benign |
Het |
| Zfp710 |
T |
A |
7: 79,740,089 (GRCm39) |
*646R |
probably null |
Het |
| Zfp90 |
C |
T |
8: 107,151,892 (GRCm39) |
S535L |
possibly damaging |
Het |
| Zfp949 |
C |
T |
9: 88,450,787 (GRCm39) |
T119I |
possibly damaging |
Het |
|
| Other mutations in Psme4 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00228:Psme4
|
APN |
11 |
30,765,710 (GRCm39) |
critical splice donor site |
probably null |
|
|
IGL00401:Psme4
|
APN |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
IGL00475:Psme4
|
APN |
11 |
30,795,252 (GRCm39) |
missense |
probably benign |
0.14 |
|
IGL00576:Psme4
|
APN |
11 |
30,773,145 (GRCm39) |
missense |
possibly damaging |
0.50 |
|
IGL00817:Psme4
|
APN |
11 |
30,770,129 (GRCm39) |
missense |
probably benign |
0.01 |
|
IGL01525:Psme4
|
APN |
11 |
30,759,936 (GRCm39) |
splice site |
probably benign |
|
|
IGL01862:Psme4
|
APN |
11 |
30,762,038 (GRCm39) |
nonsense |
probably null |
|
|
IGL02310:Psme4
|
APN |
11 |
30,787,484 (GRCm39) |
missense |
probably benign |
0.06 |
|
IGL02477:Psme4
|
APN |
11 |
30,792,083 (GRCm39) |
missense |
probably damaging |
0.99 |
|
IGL02545:Psme4
|
APN |
11 |
30,791,586 (GRCm39) |
missense |
possibly damaging |
0.81 |
|
IGL02608:Psme4
|
APN |
11 |
30,770,944 (GRCm39) |
missense |
probably benign |
0.34 |
|
IGL02621:Psme4
|
APN |
11 |
30,798,131 (GRCm39) |
missense |
probably benign |
|
|
IGL02822:Psme4
|
APN |
11 |
30,798,204 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02833:Psme4
|
APN |
11 |
30,800,715 (GRCm39) |
unclassified |
probably benign |
|
|
IGL02964:Psme4
|
APN |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
IGL03273:Psme4
|
APN |
11 |
30,798,130 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03348:Psme4
|
APN |
11 |
30,826,796 (GRCm39) |
missense |
probably damaging |
1.00 |
|
IGL03382:Psme4
|
APN |
11 |
30,757,788 (GRCm39) |
missense |
possibly damaging |
0.94 |
|
H2330:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
PIT4378001:Psme4
|
UTSW |
11 |
30,771,079 (GRCm39) |
splice site |
probably benign |
|
|
R0276:Psme4
|
UTSW |
11 |
30,761,980 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0685:Psme4
|
UTSW |
11 |
30,828,415 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R0766:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R0830:Psme4
|
UTSW |
11 |
30,757,797 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R0940:Psme4
|
UTSW |
11 |
30,765,264 (GRCm39) |
missense |
possibly damaging |
0.53 |
|
R1018:Psme4
|
UTSW |
11 |
30,754,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1312:Psme4
|
UTSW |
11 |
30,757,687 (GRCm39) |
splice site |
probably null |
|
|
R1448:Psme4
|
UTSW |
11 |
30,802,744 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1713:Psme4
|
UTSW |
11 |
30,756,310 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1732:Psme4
|
UTSW |
11 |
30,798,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R1813:Psme4
|
UTSW |
11 |
30,754,353 (GRCm39) |
missense |
probably benign |
0.14 |
|
R1905:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1907:Psme4
|
UTSW |
11 |
30,760,922 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R1911:Psme4
|
UTSW |
11 |
30,765,658 (GRCm39) |
missense |
probably benign |
0.02 |
|
R1956:Psme4
|
UTSW |
11 |
30,782,424 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R1974:Psme4
|
UTSW |
11 |
30,769,011 (GRCm39) |
missense |
probably benign |
0.00 |
|
R1980:Psme4
|
UTSW |
11 |
30,782,615 (GRCm39) |
missense |
possibly damaging |
0.84 |
|
R1986:Psme4
|
UTSW |
11 |
30,780,352 (GRCm39) |
missense |
probably benign |
0.01 |
|
R2046:Psme4
|
UTSW |
11 |
30,767,723 (GRCm39) |
splice site |
probably benign |
|
|
R2142:Psme4
|
UTSW |
11 |
30,770,998 (GRCm39) |
missense |
possibly damaging |
0.89 |
|
R2698:Psme4
|
UTSW |
11 |
30,824,282 (GRCm39) |
critical splice donor site |
probably null |
|
|
R2844:Psme4
|
UTSW |
11 |
30,795,173 (GRCm39) |
splice site |
probably benign |
|
|
R3807:Psme4
|
UTSW |
11 |
30,806,027 (GRCm39) |
splice site |
probably null |
|
|
R3876:Psme4
|
UTSW |
11 |
30,806,068 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R4420:Psme4
|
UTSW |
11 |
30,762,028 (GRCm39) |
missense |
possibly damaging |
0.67 |
|
R4584:Psme4
|
UTSW |
11 |
30,784,318 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R4615:Psme4
|
UTSW |
11 |
30,784,287 (GRCm39) |
missense |
probably benign |
0.02 |
|
R4714:Psme4
|
UTSW |
11 |
30,782,573 (GRCm39) |
missense |
probably benign |
0.02 |
|
R5008:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R5109:Psme4
|
UTSW |
11 |
30,741,095 (GRCm39) |
nonsense |
probably null |
|
|
R5155:Psme4
|
UTSW |
11 |
30,826,806 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5199:Psme4
|
UTSW |
11 |
30,803,272 (GRCm39) |
missense |
probably benign |
0.00 |
|
R5205:Psme4
|
UTSW |
11 |
30,782,666 (GRCm39) |
intron |
probably benign |
|
|
R5452:Psme4
|
UTSW |
11 |
30,741,168 (GRCm39) |
missense |
probably benign |
|
|
R5491:Psme4
|
UTSW |
11 |
30,765,246 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R5685:Psme4
|
UTSW |
11 |
30,759,837 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R5764:Psme4
|
UTSW |
11 |
30,722,364 (GRCm39) |
intron |
probably benign |
|
|
R5853:Psme4
|
UTSW |
11 |
30,741,234 (GRCm39) |
critical splice donor site |
probably null |
|
|
R5865:Psme4
|
UTSW |
11 |
30,741,993 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R5903:Psme4
|
UTSW |
11 |
30,791,589 (GRCm39) |
missense |
probably benign |
0.28 |
|
R5927:Psme4
|
UTSW |
11 |
30,754,294 (GRCm39) |
missense |
possibly damaging |
0.82 |
|
R6004:Psme4
|
UTSW |
11 |
30,806,896 (GRCm39) |
intron |
probably benign |
|
|
R6102:Psme4
|
UTSW |
11 |
30,815,567 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6247:Psme4
|
UTSW |
11 |
30,803,245 (GRCm39) |
missense |
possibly damaging |
0.60 |
|
R6527:Psme4
|
UTSW |
11 |
30,782,175 (GRCm39) |
missense |
probably benign |
|
|
R6750:Psme4
|
UTSW |
11 |
30,803,203 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R6885:Psme4
|
UTSW |
11 |
30,784,307 (GRCm39) |
nonsense |
probably null |
|
|
R6939:Psme4
|
UTSW |
11 |
30,787,291 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R6945:Psme4
|
UTSW |
11 |
30,787,437 (GRCm39) |
missense |
probably benign |
0.06 |
|
R7029:Psme4
|
UTSW |
11 |
30,722,474 (GRCm39) |
intron |
probably benign |
|
|
R7049:Psme4
|
UTSW |
11 |
30,763,904 (GRCm39) |
splice site |
probably null |
|
|
R7098:Psme4
|
UTSW |
11 |
30,800,661 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7107:Psme4
|
UTSW |
11 |
30,798,105 (GRCm39) |
missense |
probably benign |
0.03 |
|
R7223:Psme4
|
UTSW |
11 |
30,824,226 (GRCm39) |
missense |
probably benign |
0.33 |
|
R7319:Psme4
|
UTSW |
11 |
30,757,790 (GRCm39) |
missense |
probably benign |
0.00 |
|
R7375:Psme4
|
UTSW |
11 |
30,722,700 (GRCm39) |
splice site |
probably null |
|
|
R7410:Psme4
|
UTSW |
11 |
30,765,279 (GRCm39) |
nonsense |
probably null |
|
|
R7469:Psme4
|
UTSW |
11 |
30,752,837 (GRCm39) |
missense |
probably benign |
0.20 |
|
R7651:Psme4
|
UTSW |
11 |
30,787,334 (GRCm39) |
missense |
probably damaging |
0.98 |
|
R7679:Psme4
|
UTSW |
11 |
30,828,425 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R7681:Psme4
|
UTSW |
11 |
30,741,975 (GRCm39) |
missense |
possibly damaging |
0.63 |
|
R7822:Psme4
|
UTSW |
11 |
30,824,245 (GRCm39) |
missense |
probably benign |
|
|
R8013:Psme4
|
UTSW |
11 |
30,754,320 (GRCm39) |
missense |
probably benign |
0.06 |
|
R8130:Psme4
|
UTSW |
11 |
30,792,026 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8323:Psme4
|
UTSW |
11 |
30,793,532 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8330:Psme4
|
UTSW |
11 |
30,793,583 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8363:Psme4
|
UTSW |
11 |
30,762,139 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8491:Psme4
|
UTSW |
11 |
30,722,161 (GRCm39) |
missense |
possibly damaging |
0.90 |
|
R8690:Psme4
|
UTSW |
11 |
30,787,319 (GRCm39) |
missense |
probably benign |
0.00 |
|
R8696:Psme4
|
UTSW |
11 |
30,759,896 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R8743:Psme4
|
UTSW |
11 |
30,828,467 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R8998:Psme4
|
UTSW |
11 |
30,788,957 (GRCm39) |
missense |
possibly damaging |
0.78 |
|
R9241:Psme4
|
UTSW |
11 |
30,815,576 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R9657:Psme4
|
UTSW |
11 |
30,788,980 (GRCm39) |
missense |
probably benign |
0.00 |
|
R9736:Psme4
|
UTSW |
11 |
30,797,411 (GRCm39) |
missense |
probably damaging |
0.99 |
|
R9744:Psme4
|
UTSW |
11 |
30,765,294 (GRCm39) |
critical splice donor site |
probably null |
|
|
R9746:Psme4
|
UTSW |
11 |
30,826,868 (GRCm39) |
nonsense |
probably null |
|
|
V5088:Psme4
|
UTSW |
11 |
30,801,210 (GRCm39) |
missense |
probably benign |
0.17 |
|
X0063:Psme4
|
UTSW |
11 |
30,782,600 (GRCm39) |
missense |
possibly damaging |
0.66 |
|
Z1176:Psme4
|
UTSW |
11 |
30,793,522 (GRCm39) |
missense |
possibly damaging |
0.87 |
|
Z1177:Psme4
|
UTSW |
11 |
30,762,138 (GRCm39) |
missense |
probably damaging |
1.00 |
|
Z1177:Psme4
|
UTSW |
11 |
30,756,311 (GRCm39) |
missense |
probably damaging |
1.00 |
|
| Predicted Primers |
PCR Primer
(F):5'- AAGTTTAGTCCCCGGCGTTTCTG -3'
(R):5'- CGAGTCTTGGTATGACTTATGTGACCTG -3'
Sequencing Primer
(F):5'- gttcagttcccagcgacc -3'
(R):5'- CCTGGATAAATGATTAACAAAAACCC -3'
|
| Posted On |
2013-05-23 |
Incidental Mutation