Incidental Mutation 'IGL03243:Ceacam23'
| ID |
414297 |
| Institutional Source |
Australian Phenomics Network
(link to record)
|
| Gene Symbol |
Ceacam23
|
| Ensembl Gene |
ENSMUSG00000078793 |
| Gene Name |
CEA cell adhesion moleculen23 |
| Synonyms |
Gm5155 |
| Accession Numbers |
|
| Essential gene? |
Non essential
(E-score: 0.000)
|
| Stock # |
IGL03243
|
| Quality Score |
|
|
Status
|
|
| Chromosome |
7 |
| Chromosomal Location |
17605692-17652935 bp(+) (GRCm39) |
| Type of Mutation |
exon |
| DNA Base Change (assembly) |
A to T
at 17652574 bp (GRCm39)
|
| Zygosity |
Heterozygous |
| Amino Acid Change |
|
| Gene Model |
predicted gene model for transcript(s):
|
| AlphaFold |
A0A3Q4EGJ1 |
| Predicted Effect |
noncoding transcript
Transcript: ENSMUST00000072381
|
| SMART Domains |
Protein: ENSMUSP00000072218
Gene: ENSMUSG00000078793
| Domain | Start | End | E-Value | Type |
|---|
|
IG
|
40 |
141 |
2.27e-2 |
SMART |
|
IG_like
|
160 |
261 |
2.73e1 |
SMART |
|
IG_like
|
277 |
378 |
6.69e0 |
SMART |
|
IG_like
|
397 |
498 |
4.07e1 |
SMART |
|
IG_like
|
514 |
615 |
6.52e0 |
SMART |
|
IG_like
|
634 |
735 |
1.05e1 |
SMART |
|
IG
|
753 |
853 |
1.28e-1 |
SMART |
|
IGc2
|
869 |
933 |
3.82e-9 |
SMART |
|
| Coding Region Coverage |
|
| Validation Efficiency |
|
| Allele List at MGI |
|
| Other mutations in this stock |
Total: 31 list
| Gene | Ref | Var | Chr/Loc | Mutation | Predicted Effect | Zygosity |
|---|
| Adam26a |
T |
C |
8: 44,021,733 (GRCm39) |
T586A |
probably benign |
Het |
| Agtr1b |
T |
C |
3: 20,369,959 (GRCm39) |
T216A |
probably benign |
Het |
| Ankdd1a |
T |
C |
9: 65,408,752 (GRCm39) |
R505G |
probably benign |
Het |
| Anxa3 |
A |
T |
5: 96,976,551 (GRCm39) |
|
probably benign |
Het |
| Atp6v1c2 |
C |
T |
12: 17,339,122 (GRCm39) |
V210I |
probably benign |
Het |
| BC034090 |
G |
A |
1: 155,101,401 (GRCm39) |
P288S |
possibly damaging |
Het |
| Catsper2 |
T |
C |
2: 121,237,300 (GRCm39) |
H200R |
probably benign |
Het |
| Cntnap5c |
G |
T |
17: 58,409,171 (GRCm39) |
A470S |
probably benign |
Het |
| Fcho2 |
G |
A |
13: 98,913,892 (GRCm39) |
|
probably benign |
Het |
| Frem1 |
A |
C |
4: 82,932,206 (GRCm39) |
L165R |
probably damaging |
Het |
| Gpn1 |
G |
A |
5: 31,668,175 (GRCm39) |
|
probably null |
Het |
| Gpr179 |
T |
C |
11: 97,242,301 (GRCm39) |
N181S |
probably benign |
Het |
| Heatr5b |
A |
T |
17: 79,070,509 (GRCm39) |
|
probably benign |
Het |
| Kat6a |
A |
G |
8: 23,400,238 (GRCm39) |
N333S |
possibly damaging |
Het |
| Lrp5 |
T |
C |
19: 3,680,159 (GRCm39) |
T442A |
probably benign |
Het |
| Myo15a |
G |
T |
11: 60,387,344 (GRCm39) |
L722F |
probably damaging |
Het |
| Nlrp9c |
T |
G |
7: 26,064,457 (GRCm39) |
D957A |
probably damaging |
Het |
| Nup58 |
T |
A |
14: 60,459,065 (GRCm39) |
T521S |
probably benign |
Het |
| Or7e165 |
T |
G |
9: 19,694,564 (GRCm39) |
I45S |
probably damaging |
Het |
| Plek |
C |
A |
11: 16,945,319 (GRCm39) |
V4L |
possibly damaging |
Het |
| Sell |
T |
A |
1: 163,892,911 (GRCm39) |
H42Q |
possibly damaging |
Het |
| Slfn8 |
A |
T |
11: 82,894,533 (GRCm39) |
I702K |
probably damaging |
Het |
| Svep1 |
T |
C |
4: 58,133,387 (GRCm39) |
I573V |
probably benign |
Het |
| Tgm1 |
T |
A |
14: 55,943,364 (GRCm39) |
I526F |
probably damaging |
Het |
| Tmem30c |
A |
T |
16: 57,096,513 (GRCm39) |
S203T |
probably benign |
Het |
| Tox |
T |
C |
4: 6,697,597 (GRCm39) |
N402S |
possibly damaging |
Het |
| Trav7d-4 |
C |
A |
14: 53,007,555 (GRCm39) |
|
probably benign |
Het |
| Unc13d |
A |
T |
11: 115,958,670 (GRCm39) |
V784D |
probably benign |
Het |
| Vmn2r68 |
A |
G |
7: 84,882,963 (GRCm39) |
V263A |
possibly damaging |
Het |
| Zfp385c |
A |
T |
11: 100,525,573 (GRCm39) |
V56D |
probably damaging |
Het |
| Znrf2 |
A |
T |
6: 54,861,754 (GRCm39) |
I222L |
possibly damaging |
Het |
|
| Other mutations in Ceacam23 |
| Allele | Source | Chr | Coord | Type | Predicted Effect | PPH Score |
|---|
|
IGL00480:Ceacam23
|
APN |
7 |
17,644,622 (GRCm39) |
missense |
probably benign |
0.32 |
|
IGL01085:Ceacam23
|
APN |
7 |
17,649,616 (GRCm39) |
missense |
possibly damaging |
0.71 |
|
IGL01135:Ceacam23
|
APN |
7 |
17,636,396 (GRCm39) |
exon |
noncoding transcript |
|
|
IGL01291:Ceacam23
|
APN |
7 |
17,639,041 (GRCm39) |
exon |
noncoding transcript |
|
|
IGL02252:Ceacam23
|
APN |
7 |
17,644,457 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R0113:Ceacam23
|
UTSW |
7 |
17,642,873 (GRCm39) |
exon |
noncoding transcript |
|
|
R0833:Ceacam23
|
UTSW |
7 |
17,638,906 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R0836:Ceacam23
|
UTSW |
7 |
17,638,906 (GRCm39) |
missense |
possibly damaging |
0.95 |
|
R1462:Ceacam23
|
UTSW |
7 |
17,649,516 (GRCm39) |
exon |
noncoding transcript |
|
|
R1473:Ceacam23
|
UTSW |
7 |
17,639,016 (GRCm39) |
exon |
noncoding transcript |
|
|
R1817:Ceacam23
|
UTSW |
7 |
17,607,255 (GRCm39) |
exon |
noncoding transcript |
|
|
R1905:Ceacam23
|
UTSW |
7 |
17,607,477 (GRCm39) |
exon |
noncoding transcript |
|
|
R2362:Ceacam23
|
UTSW |
7 |
17,636,398 (GRCm39) |
exon |
noncoding transcript |
|
|
R3721:Ceacam23
|
UTSW |
7 |
17,636,663 (GRCm39) |
missense |
probably benign |
0.41 |
|
R4305:Ceacam23
|
UTSW |
7 |
17,639,118 (GRCm39) |
missense |
probably benign |
0.19 |
|
R4567:Ceacam23
|
UTSW |
7 |
17,642,891 (GRCm39) |
missense |
probably damaging |
0.97 |
|
R4587:Ceacam23
|
UTSW |
7 |
17,620,149 (GRCm39) |
missense |
possibly damaging |
0.47 |
|
R4691:Ceacam23
|
UTSW |
7 |
17,642,891 (GRCm39) |
missense |
possibly damaging |
0.93 |
|
R4989:Ceacam23
|
UTSW |
7 |
17,639,143 (GRCm39) |
splice site |
probably null |
|
|
R5023:Ceacam23
|
UTSW |
7 |
17,636,631 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5024:Ceacam23
|
UTSW |
7 |
17,644,607 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5274:Ceacam23
|
UTSW |
7 |
17,649,642 (GRCm39) |
splice site |
probably null |
|
|
R5279:Ceacam23
|
UTSW |
7 |
17,607,214 (GRCm39) |
splice site |
noncoding transcript |
|
|
R5304:Ceacam23
|
UTSW |
7 |
17,636,617 (GRCm39) |
missense |
probably benign |
0.06 |
|
R5312:Ceacam23
|
UTSW |
7 |
17,643,067 (GRCm39) |
missense |
probably damaging |
1.00 |
|
R5899:Ceacam23
|
UTSW |
7 |
17,651,369 (GRCm39) |
missense |
possibly damaging |
0.92 |
|
| Posted On |
2016-08-02 |
Incidental Mutation