Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03273:Gm11937'

415332

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Gm11937

Ensembl Gene

ENSMUSG00000058725

Gene Name

predicted gene 11937

Synonyms

Accession Numbers

Essential gene?

Not available question?

Stock #

IGL03273

Quality Score

Status

Chromosome

Chromosomal Location

99500620-99501015 bp(-) (GRCm39)

Type of Mutation

unclassified

DNA Base Change (assembly)

C to T at 99500627 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000074461 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000074926] [ENSMUST00000076478]

AlphaFold

no structure available at present

Predicted Effect

probably benign
Transcript: ENSMUST00000074926

SMART Domains

Protein: ENSMUSP00000074461
Gene: ENSMUSG00000060756

Domain	Start	End	E-Value	Type
Pfam:Keratin_B2_2	1	56	5.8e-4	PFAM
Pfam:Keratin_B2	1	72	2.6e-12	PFAM
Pfam:Keratin_B2_2	53	101	1.3e-5	PFAM
Pfam:Keratin_B2_2	92	131	6.1e-4	PFAM

Predicted Effect

unknown
Transcript: ENSMUST00000076478
AA Change: C130Y

SMART Domains

Protein: ENSMUSP00000075802
Gene: ENSMUSG00000058725
AA Change: C130Y

Domain	Start	End	E-Value	Type
Pfam:Keratin_B2_2	1	56	5.8e-4	PFAM
Pfam:Keratin_B2	1	72	2.6e-12	PFAM
Pfam:Keratin_B2_2	53	101	1.3e-5	PFAM
Pfam:Keratin_B2_2	92	131	6.1e-4	PFAM

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 26 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Aaas	A	G	15: 102,258,430 (GRCm39)	I29T	probably damaging	Het
Adam32	T	A	8: 25,411,356 (GRCm39)	I102F	probably damaging	Het
Aldoart1	T	C	4: 72,770,346 (GRCm39)	K154R	probably benign	Het
Cdin1	A	G	2: 115,462,472 (GRCm39)	Y68C	probably damaging	Het
Cep63	T	C	9: 102,479,666 (GRCm39)	K349E	probably benign	Het
Col28a1	A	G	6: 8,103,484 (GRCm39)		probably benign	Het
Dennd4c	A	G	4: 86,696,033 (GRCm39)	N130S	probably damaging	Het
Dnah5	T	G	15: 28,458,795 (GRCm39)	F4477L	probably damaging	Het
Fbln7	A	T	2: 128,737,390 (GRCm39)	T402S	probably benign	Het
Frem2	A	C	3: 53,444,930 (GRCm39)	Y2400*	probably null	Het
Guca1a	T	C	17: 47,706,098 (GRCm39)	D127G	probably benign	Het
Hrh3	T	A	2: 179,742,441 (GRCm39)	T396S	possibly damaging	Het
Map1a	A	G	2: 121,130,719 (GRCm39)	N512D	probably damaging	Het
Mysm1	A	C	4: 94,853,955 (GRCm39)	S215A	probably damaging	Het
Nelfcd	G	A	2: 174,268,625 (GRCm39)	A559T	possibly damaging	Het
Nup93	T	A	8: 95,032,905 (GRCm39)	D556E	probably benign	Het
Ofcc1	T	A	13: 40,334,001 (GRCm39)	K363N	probably damaging	Het
Psme4	T	A	11: 30,798,130 (GRCm39)	S1374R	probably damaging	Het
Samt2b	A	T	X: 153,122,697 (GRCm39)	F114L	probably benign	Het
Slitrk2	T	C	X: 65,697,602 (GRCm39)	I31T	probably benign	Het
Stk40	A	G	4: 126,017,599 (GRCm39)	N42S	possibly damaging	Het
Tarbp1	A	G	8: 127,180,574 (GRCm39)	L600P	probably damaging	Het
Tjp1	T	C	7: 64,949,547 (GRCm39)	S1692G	probably damaging	Het
Tmem63c	G	T	12: 87,128,576 (GRCm39)	V534L	probably damaging	Het
Vmn2r77	A	G	7: 86,460,494 (GRCm39)	K607E	probably damaging	Het
Zfp292	A	T	4: 34,806,163 (GRCm39)	S2299T	probably benign	Het

Other mutations in Gm11937

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
R1355:Gm11937	UTSW	11	99,500,733 (GRCm39)	missense	possibly damaging	0.94
R4401:Gm11937	UTSW	11	99,500,901 (GRCm39)	missense	probably damaging	1.00
R6736:Gm11937	UTSW	11	99,500,900 (GRCm39)	missense	probably damaging	0.97
R9495:Gm11937	UTSW	11	99,500,646 (GRCm39)	missense	unknown

Posted On

2016-08-02