Incidental Mutation 'IGL03274:Gm5422'
ID 415353
Institutional Source Australian Phenomics Network (link to record)
Gene Symbol Gm5422
Ensembl Gene ENSMUSG00000039684
Gene Name predicted pseudogene 5422
Synonyms
Accession Numbers
Essential gene? Probably essential (E-score: 0.915) question?
Stock # IGL03274
Quality Score
Status
Chromosome 10
Chromosomal Location 31124133-31127039 bp(+) (GRCm39)
Type of Mutation exon
DNA Base Change (assembly) G to T at 31126348 bp (GRCm39)
Zygosity Heterozygous
Amino Acid Change
Gene Model predicted gene model for transcript(s):
AlphaFold no structure available at present
Predicted Effect noncoding transcript
Transcript: ENSMUST00000050717
SMART Domains Protein: ENSMUSP00000135967
Gene: ENSMUSG00000039684

DomainStartEndE-ValueType
low complexity region 44 61 N/A INTRINSIC
Pfam:PC_rep 438 474 6.8e-9 PFAM
Pfam:PC_rep 475 509 1.1e-8 PFAM
SCOP:d1gw5a_ 603 760 4e-4 SMART
PDB:4CR4|Z 648 901 1e-50 PDB
Predicted Effect noncoding transcript
Transcript: ENSMUST00000216161
Coding Region Coverage
Validation Efficiency
Allele List at MGI
Other mutations in this stock
Total: 32 list
GeneRefVarChr/LocMutationPredicted EffectZygosity
Adissp A T 2: 130,995,512 (GRCm39) probably null Het
Anln C A 9: 22,293,565 (GRCm39) R26M probably damaging Het
Capn15 A T 17: 26,180,812 (GRCm39) S753T probably damaging Het
Ccdc62 A G 5: 124,092,743 (GRCm39) N576S probably benign Het
Csmd3 T C 15: 47,508,900 (GRCm39) D2895G probably damaging Het
Dspp T A 5: 104,322,814 (GRCm39) V37E probably damaging Het
Efcab3 A T 11: 104,611,919 (GRCm39) D587V probably benign Het
Efcab6 T C 15: 83,752,450 (GRCm39) D1473G probably damaging Het
Ehhadh T C 16: 21,582,090 (GRCm39) probably benign Het
Fbln1 T C 15: 85,116,879 (GRCm39) probably null Het
Gbp9 A G 5: 105,230,652 (GRCm39) V424A possibly damaging Het
Gda T C 19: 21,394,371 (GRCm39) Y236C possibly damaging Het
Gm4884 A G 7: 40,693,969 (GRCm39) E646G probably damaging Het
Gm4952 C A 19: 12,600,960 (GRCm39) probably benign Het
Grin2b C T 6: 135,757,253 (GRCm39) D403N possibly damaging Het
Hsf2bp G A 17: 32,226,744 (GRCm39) R204C probably damaging Het
Il16 T C 7: 83,310,442 (GRCm39) E488G probably damaging Het
Kat6b G T 14: 21,659,831 (GRCm39) D212Y possibly damaging Het
Kctd2 A C 11: 115,320,208 (GRCm39) I247L possibly damaging Het
Kel T A 6: 41,664,929 (GRCm39) probably null Het
Krt20 A T 11: 99,320,855 (GRCm39) probably benign Het
Litaf T C 16: 10,784,433 (GRCm39) T26A probably damaging Het
N4bp2l2 G T 5: 150,584,931 (GRCm39) Q350K probably damaging Het
Nav2 T G 7: 49,011,847 (GRCm39) I26S probably damaging Het
Nfya A G 17: 48,698,375 (GRCm39) Y162H probably damaging Het
Or2g25 C T 17: 37,970,646 (GRCm39) A193T probably benign Het
Pbx4 A T 8: 70,319,200 (GRCm39) S244C probably damaging Het
Pcdhb16 T C 18: 37,612,285 (GRCm39) V415A probably benign Het
Rbbp8 A G 18: 11,874,133 (GRCm39) probably benign Het
Sp100 T C 1: 85,635,025 (GRCm39) probably benign Het
Spag16 A G 1: 69,883,540 (GRCm39) probably benign Het
Star A G 8: 26,301,082 (GRCm39) D138G possibly damaging Het
Other mutations in Gm5422
AlleleSourceChrCoordTypePredicted EffectPPH Score
IGL01306:Gm5422 APN 10 31,125,432 (GRCm39) exon noncoding transcript
IGL01569:Gm5422 APN 10 31,125,897 (GRCm39) exon noncoding transcript
IGL01645:Gm5422 APN 10 31,126,069 (GRCm39) exon noncoding transcript
IGL02273:Gm5422 APN 10 31,126,003 (GRCm39) exon noncoding transcript
IGL02603:Gm5422 APN 10 31,125,436 (GRCm39) exon noncoding transcript
IGL02928:Gm5422 APN 10 31,126,250 (GRCm39) exon noncoding transcript
IGL03003:Gm5422 APN 10 31,126,840 (GRCm39) exon noncoding transcript
IGL03297:Gm5422 APN 10 31,125,727 (GRCm39) exon noncoding transcript
ANU23:Gm5422 UTSW 10 31,125,432 (GRCm39) exon noncoding transcript
R0010:Gm5422 UTSW 10 31,125,750 (GRCm39) exon noncoding transcript
R0506:Gm5422 UTSW 10 31,126,318 (GRCm39) exon noncoding transcript
R0560:Gm5422 UTSW 10 31,125,240 (GRCm39) exon noncoding transcript
R0573:Gm5422 UTSW 10 31,126,156 (GRCm39) exon noncoding transcript
R0652:Gm5422 UTSW 10 31,125,277 (GRCm39) exon noncoding transcript
R1210:Gm5422 UTSW 10 31,126,719 (GRCm39) intron noncoding transcript
R1259:Gm5422 UTSW 10 31,125,111 (GRCm39) exon noncoding transcript
R1352:Gm5422 UTSW 10 31,126,731 (GRCm39) intron noncoding transcript
R1631:Gm5422 UTSW 10 31,125,802 (GRCm39) exon noncoding transcript
R1707:Gm5422 UTSW 10 31,124,458 (GRCm39) exon noncoding transcript
R1893:Gm5422 UTSW 10 31,125,609 (GRCm39) exon noncoding transcript
R2011:Gm5422 UTSW 10 31,124,764 (GRCm39) exon noncoding transcript
R2132:Gm5422 UTSW 10 31,124,929 (GRCm39) exon noncoding transcript
R3427:Gm5422 UTSW 10 31,124,842 (GRCm39) exon noncoding transcript
R3772:Gm5422 UTSW 10 31,124,510 (GRCm39) exon noncoding transcript
R4703:Gm5422 UTSW 10 31,125,608 (GRCm39) exon noncoding transcript
R5539:Gm5422 UTSW 10 31,124,646 (GRCm39) exon noncoding transcript
R5603:Gm5422 UTSW 10 31,126,840 (GRCm39) exon noncoding transcript
R5660:Gm5422 UTSW 10 31,126,048 (GRCm39) exon noncoding transcript
R6124:Gm5422 UTSW 10 31,125,396 (GRCm39) exon noncoding transcript
R6178:Gm5422 UTSW 10 31,125,688 (GRCm39) exon noncoding transcript
R8263:Gm5422 UTSW 10 31,125,099 (GRCm39) missense noncoding transcript
Posted On 2016-08-02