Mutagenetix > Incidental Mutation

Incidental Mutation 'IGL03288:Prr11'

415810

Institutional Source

Australian Phenomics Network (link to record)

Gene Symbol

Prr11

Ensembl Gene

ENSMUSG00000020493

Gene Name

proline rich 11

Synonyms

B930067F20Rik

Accession Numbers

Essential gene?

Probably non essential (E-score: 0.071) question?

Stock #

IGL03288

Quality Score

Status

Chromosome

Chromosomal Location

86979979-86999534 bp(-) (GRCm39)

Type of Mutation

critical splice donor site (2 bp from exon)

DNA Base Change (assembly)

A to C at 86987787 bp (GRCm39)

Zygosity

Heterozygous

Amino Acid Change

Ref Sequence

ENSEMBL: ENSMUSP00000060803 (fasta)

Gene Model

predicted gene model for transcript(s): [ENSMUST00000051395]

AlphaFold

Q8BHE0

Predicted Effect

probably null
Transcript: ENSMUST00000051395

SMART Domains

Protein: ENSMUSP00000060803
Gene: ENSMUSG00000020493

Domain	Start	End	E-Value	Type
low complexity region	3	25	N/A	INTRINSIC
low complexity region	28	42	N/A	INTRINSIC
low complexity region	135	152	N/A	INTRINSIC
low complexity region	184	212	N/A	INTRINSIC
low complexity region	350	363	N/A	INTRINSIC

Coding Region Coverage

Validation Efficiency

Allele List at MGI

Other mutations in this stock

Total: 42 list
Gene	Ref	Var	Chr/Loc	Mutation	Predicted Effect	Zygosity
Arap2	T	C	5: 62,761,959 (GRCm39)	K1589R	probably benign	Het
Armc3	T	C	2: 19,240,293 (GRCm39)	F17L	probably damaging	Het
Ccdc17	T	A	4: 116,456,626 (GRCm39)	L465H	probably damaging	Het
Cdh9	A	T	15: 16,856,135 (GRCm39)	D725V	probably damaging	Het
Cert1	T	A	13: 96,770,700 (GRCm39)	D536E	probably benign	Het
Chl1	C	T	6: 103,652,058 (GRCm39)	R309C	probably damaging	Het
Dbt	T	A	3: 116,341,847 (GRCm39)	*483K	probably null	Het
Ddx46	A	G	13: 55,785,907 (GRCm39)	D29G	unknown	Het
Des	T	C	1: 75,338,985 (GRCm39)	I222T	possibly damaging	Het
Dnah8	A	G	17: 30,891,323 (GRCm39)	N776S	probably benign	Het
Fbn1	A	T	2: 125,145,103 (GRCm39)	L2712Q	probably benign	Het
Glb1l3	A	C	9: 26,729,601 (GRCm39)	V622G	probably damaging	Het
Grin2a	T	C	16: 9,487,704 (GRCm39)	D398G	possibly damaging	Het
Itgb3	T	C	11: 104,524,293 (GRCm39)	M143T	probably damaging	Het
Lama2	G	A	10: 27,245,047 (GRCm39)	R245C	probably damaging	Het
Lgals9	G	A	11: 78,875,626 (GRCm39)	A6V	probably benign	Het
Lman2l	A	T	1: 36,482,628 (GRCm39)	Y83N	probably damaging	Het
Lrp2	T	A	2: 69,256,383 (GRCm39)	T4586S	probably benign	Het
Med10	T	C	13: 69,963,816 (GRCm39)		probably benign	Het
Myo18b	A	C	5: 112,937,863 (GRCm39)	L1754R	probably damaging	Het
Myom2	T	C	8: 15,172,679 (GRCm39)	L1202S	probably damaging	Het
Nav3	T	C	10: 109,594,878 (GRCm39)	E1441G	probably damaging	Het
Nme8	T	C	13: 19,880,776 (GRCm39)	E60G	possibly damaging	Het
Npffr2	G	T	5: 89,731,020 (GRCm39)	A317S	probably damaging	Het
Nrxn2	A	G	19: 6,540,726 (GRCm39)	D893G	probably damaging	Het
Nup153	T	C	13: 46,858,681 (GRCm39)	E410G	possibly damaging	Het
Or11h7	T	C	14: 50,890,832 (GRCm39)	I46T	possibly damaging	Het
Or7e178	A	G	9: 20,247,207 (GRCm39)		probably null	Het
Pcdhb10	A	G	18: 37,546,358 (GRCm39)	D478G	probably damaging	Het
Phf13	T	C	4: 152,076,826 (GRCm39)	D122G	possibly damaging	Het
Pkhd1	A	T	1: 20,271,243 (GRCm39)	H3103Q	probably benign	Het
Rac3	C	T	11: 120,614,092 (GRCm39)	T118M	possibly damaging	Het
Rad54b	T	C	4: 11,569,833 (GRCm39)	S50P	possibly damaging	Het
Rp1	T	C	1: 4,419,747 (GRCm39)	Q455R	possibly damaging	Het
Semp2l1	T	A	1: 32,584,841 (GRCm39)	E356D	probably benign	Het
Sorl1	T	C	9: 41,944,858 (GRCm39)		probably benign	Het
Spink5	A	T	18: 44,147,827 (GRCm39)	I858F	possibly damaging	Het
Stxbp5	A	T	10: 9,742,447 (GRCm39)		probably null	Het
Svep1	A	C	4: 58,116,532 (GRCm39)	V906G	probably benign	Het
Tlr4	A	G	4: 66,757,990 (GRCm39)	E261G	probably damaging	Het
Zfp704	C	T	3: 9,504,951 (GRCm39)		probably benign	Het
Zfyve9	A	T	4: 108,580,996 (GRCm39)		probably benign	Het

Other mutations in Prr11

Allele	Source	Chr	Coord	Type	Predicted Effect	PPH Score
IGL00797:Prr11	APN	11	86,989,505 (GRCm39)	missense	probably benign
IGL02106:Prr11	APN	11	86,994,141 (GRCm39)	splice site	probably benign
IGL02733:Prr11	APN	11	86,994,371 (GRCm39)	missense	possibly damaging	0.90
IGL03052:Prr11	APN	11	86,994,478 (GRCm39)	missense	possibly damaging	0.66
R1931:Prr11	UTSW	11	86,996,868 (GRCm39)	nonsense	probably null
R1972:Prr11	UTSW	11	86,989,580 (GRCm39)	missense	possibly damaging	0.94
R1981:Prr11	UTSW	11	86,994,116 (GRCm39)	missense	probably damaging	0.99
R4499:Prr11	UTSW	11	86,989,533 (GRCm39)	missense	possibly damaging	0.82
R4500:Prr11	UTSW	11	86,989,533 (GRCm39)	missense	possibly damaging	0.82
R4837:Prr11	UTSW	11	86,989,517 (GRCm39)	missense	probably benign	0.00
R6163:Prr11	UTSW	11	86,994,454 (GRCm39)	missense	possibly damaging	0.92
R6172:Prr11	UTSW	11	86,994,449 (GRCm39)	missense	probably benign	0.02
R6389:Prr11	UTSW	11	86,989,564 (GRCm39)	missense	possibly damaging	0.92
R6469:Prr11	UTSW	11	86,988,003 (GRCm39)	missense	possibly damaging	0.46
R6505:Prr11	UTSW	11	86,996,950 (GRCm39)	nonsense	probably null
R7372:Prr11	UTSW	11	86,989,600 (GRCm39)	missense	probably benign	0.01
R7710:Prr11	UTSW	11	86,994,433 (GRCm39)	missense	probably benign	0.10
R7983:Prr11	UTSW	11	86,982,637 (GRCm39)	missense	possibly damaging	0.90
R8798:Prr11	UTSW	11	86,996,881 (GRCm39)	missense	unknown
R9065:Prr11	UTSW	11	86,992,249 (GRCm39)	missense	probably damaging	0.96
R9416:Prr11	UTSW	11	86,992,254 (GRCm39)	nonsense	probably null
R9602:Prr11	UTSW	11	86,987,998 (GRCm39)	missense	possibly damaging	0.90
R9752:Prr11	UTSW	11	86,994,416 (GRCm39)	missense	possibly damaging	0.66
Z1176:Prr11	UTSW	11	86,987,968 (GRCm39)	missense	possibly damaging	0.46

Posted On

2016-08-02